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Appendiceal mucinous neoplasm

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https://www.readbyqxmd.com/read/29719746/sister-mary-joseph-nodule-as-a-cutaneous-manifestation-of-metastatic-appendiceal-adenocarcinoma-case-report-and-literature-review
#1
Raghavendra L Girijala, Ryan R Riahi, Philip R Cohen
Sister Mary Joseph nodule (SMJN) is an uncommon pattern of superficial periumbilical tumor metastasis, with the primary tumor most commonly associated with gynecological or gastrointestinal origins. This manifestation can represent extensive tumor development from any of the intra-abdominal or pelvic structures. Therefore, SMJN carries a poor prognosis, with a two-year survival rate of only 13.5 percent regardless of the etiology of primary cancer. In this case, a 67-year-old man with metastatic mucinous adenocarcinoma of the appendix involving the umbilicus presenting more than five years after the initial cancer diagnosis is reported...
February 28, 2018: Curēus
https://www.readbyqxmd.com/read/29698881/goblet-cell-carcinoid-of-the-appendix-case-report-of-a-high-grade-tumor-in-a-20-year-old
#2
Ameen Barghi, John Grabbe, Arundhati Ghosh
INTRODUCTION: Goblet cell carcinoid (GCC) is an extraordinarily rare appendiceal tumor that is usually an incidental diagnosis on post-operative histology. It typically presents in the fifth or sixth decade of life. Our patient is the only reported case study of GCC in a pediatric-young adult. Due to its potentially poor prognosis, GCC is surgically treated as an adenocarcinoma, with right hemicolectomy as the mainstay of treatment. PRESENTATION OF CASE: The patient was a 20-year-old male who presented with a history, physical exam, and work up consistent with acute appendicitis...
April 16, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29676706/-a-man-with-abdominal-pain-diarrhoea-and-rectal-bleeding
#3
A J M Oosterwijk, J W van den Berg, C C van Rossem
A 49-year-old man came to the emergency room with abdominal pain, vomiting, diarrhoea and rectal bleeding. Both colonoscopy and CT of the abdomen showed cecocolic intussusception caused by an appendiceal mucocele. An ileocecal resection was performed via a laparoscopic approach and microscopy of the tissue showed a low-grade mucinous neoplasm.
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29580358/clinicopathological-features-and-management-of-appendiceal-mucoceles-a-systematic-review
#4
REVIEW
William F Morano, Elizabeth M Gleeson, Sean H Sullivan, Vennila Padmanaban, Beth L Mapow, Patricia A Shewokis, Jesus Esquivel, Wilbur B Bowne
Appendiceal mucoceles (AMs) are rare mucin-containing neoplasms with malignant potential. Lack of evidence-based data exists defining clinicopathological features for management. MEDLINE search between 1995 and 2015 was performed using search criteria "Appendix mucocele." Systematic review of patient-, pathologic-, and treatment-related characteristics was performed and data analyzed. Among 276 cases of non-perforated AMs, 163 (59%) patients were female, with variable and nonspecific presentation...
February 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29564494/mucinous-appendiceal-neoplasms-pathologic-classification-clinical-implications-imaging-spectrum-and-mimics
#5
REVIEW
Alanna Van Hooser, Todd R Williams, Daniel T Myers
Mucinous appendiceal neoplasms are uncommon, but important to recognize with imaging due to malignant potential. Peritoneal seeding and pseudomyxoma peritonei can occur with both frankly malignant as well as low-grade appendiceal neoplasms. Prospective imaging identification of potential appendiceal neoplasm is paramount to clinical/surgical management. When a mucinous appendiceal neoplasm is suspected, a right hemicolectomy with lymph node dissection is the preferred surgical management. Unfortunately, accurate preoperative diagnosis can be challenging due to a wide range of clinical presentations and overlapping imaging appearances of appendiceal neoplasms with benign entities...
March 21, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29487003/satb2-is-a-supportive-marker-for-the-differentiation-of-a-primary-mucinous-tumor-of-the-ovary-and-an-ovarian-metastasis-of-a-low-grade-appendiceal-mucinous-neoplasm-lamn-a-series-of-seven-cases
#6
Elisa Schmoeckel, Thomas Kirchner, Doris Mayr
The differentiation between a primary mucinous ovarian neoplasm and an extra-ovarian metastasis in the ovary is often challenging in the histopathologic practice. Among various ovarian metastases from the gastro-intestinal tract the low-grade appendiceal mucinous neoplasm (LAMN) is an important differential diagnosis to consider particularly in case of pseudomyxoma peritonei. A newly recognized marker in the routine diagnostic of a mucinous neoplasm in the ovary is SATB2 (Special AT-rich sequence-binding protein 2)...
March 2018: Pathology, Research and Practice
https://www.readbyqxmd.com/read/29428475/peritoneal-metastases-invading-the-seminal-vesicles-radiologic-appearance-and-outcome-of-treatment
#7
Paul H Sugarbaker
BACKGROUND: Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) may be of greatest benefit if all visible evidence of disease is resected. In some male patients the peritoneal metastases within the pelvis are invasive into the seminal vesicles and complete cytoreduction requires resection of these structures. PATIENTS AND METHODS: From a prospective database of colorectal and appendiceal cancer patients who had CT evidence of seminal vesicle involvement and then had cytoreduction including resection of the seminal vesicles were reviewed...
January 12, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29352970/an-uncommon-cecal-bulge-caused-by-a-large-appendiceal-mucinous-neoplasm
#8
Michael Xiang Ma, Jee Kong, Simon Hillery, Kim Cheah
No abstract text is available yet for this article.
January 17, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29352430/correction-to-clinical-surveillance-after-macroscopically-complete-surgery-for-low-grade-appendiceal-mucinous-neoplasms-lamn-with-or-without-limited-peritoneal-spread-long-term-results-in-a-prospective-series
#9
Marcello Guaglio, Snita Sinukumar, Shigeki Kusamura, Massimo Milione, Filippo Pietrantonio, Luigi Battaglia, Stefano Guadagni, Dario Baratti, Marcello Deraco
In the original article Massimo Milione's last name was spelled incorrectly. It is correct as reflected here. The original article has also been updated.
January 19, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29331663/a-multicenter-randomized-trial-to-evaluate-hematologic-toxicities-after-hyperthermic-intraperitoneal-chemotherapy-with-oxaliplatin-or-mitomycin-in-patients-with-appendiceal-tumors
#10
Edward A Levine, Konstantinos I Votanopoulos, Perry Shen, Greg Russell, Joyce Fenstermaker, Paul Mansfield, David Bartlett, John H Stewart
BACKGROUND: Appendiceal cancer is a rare disease that has proven difficult to study in prospective trials. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) is an established therapy for peritoneal dissemination from appendiceal cancer. The optimal chemotherapeutic agent to use in the HIPEC is not clear. Mitomycin has long been used, however, our previous phase I experience and European retrospective studies suggest oxaliplatin as an alternative. Therefore, we initiated a multicenter randomized trial to compare mitomycin with oxaliplatin HIPEC for appendiceal cancer...
April 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29317549/appendiceal-mucinous-neoplasms-diagnosis-and-management
#11
Walid L Shaib, Rita Assi, Ali Shamseddine, Olatunji B Alese, Charles Staley, Bahar Memis, Volkan Adsay, Tanios Bekaii-Saab, Bassel F El-Rayes
No abstract text is available yet for this article.
January 2018: Oncologist
https://www.readbyqxmd.com/read/29316120/low-grade-appendiceal-mucinous-neoplasm-within-an-amyand-s-hernia
#12
Han Boon Oh, Yudong Chen, Yuen Soon
No abstract text is available yet for this article.
January 8, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29282599/histologic-predictors-of-recurrence-in-mucinous-appendiceal-tumors-with-peritoneal-dissemination-after-hipec
#13
Meera Reghunathan, Kaitlyn J Kelly, Mark A Valasek, Andrew M Lowy, Joel M Baumgartner
BACKGROUND: Mucinous appendiceal tumors (MAT) are rare neoplasms that can metastasize to the peritoneum and often are treated with cytoreductive surgery (CRS) and HIPEC. Pathologic classification and outcomes vary, but standardized histologic definitions are emerging. We sought to evaluate outcomes in this disease after CRS/HIPEC using standardized pathologic criteria. METHOD: Outcomes of MAT with peritoneal metastases (PM) after CRS/HIPEC from 2007 to 2015 were reviewed at our institution...
March 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29258523/low-grade-appendiceal-mucinous-neoplasm-and-endometriosis-of-the-appendix
#14
Kyle D Klingbeil, Basem Azab, Mecker G Moller
BACKGROUND: A distended, mucous-filled appendix is known as an appendiceal mucocele. They are a rare form of an appendiceal mass and develop from both benign and malignant processes. Mucoceles can develop secondarily to an obstruction, such as from a fecalith, scarring or, rarely, endometriosis. Only 12 cases of non-neoplastic appendiceal mucoceles caused by endometriosis have been previously described. The association between neoplastic appendiceal mucoceles in the presence of endometriosis is described for the first time in this report...
December 19, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29159742/validation-of-the-recent-psogi-pathological-classification-of-pseudomyxoma-peritonei-in-a-single-center-series-of-265-patients-treated-by-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy
#15
Dario Baratti, Shigeki Kusamura, Massimo Milione, Federica Bruno, Marcello Guaglio, Marcello Deraco
BACKGROUND: Controversies still persist regarding the terminology and pathologic classification of appendiceal mucinous neoplasms and associated pseudomyxoma peritonei (PMP). We assessed reproducibility and prognostic significance of the classification recently proposed by the Peritoneal Surface Oncology Group International (PSOGI). METHODS: A prospective database of 265 PMP patients uniformly treated by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) from 1995 to 2017 was reviewed...
February 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29098385/incidental-appendectomy-during-robotic-laparoscopic-prostatectomy-safe-and-worth-to-perform
#16
C Hüttenbrink, G Hatiboglu, T Simpfendörfer, J P Radtke, R Becker, D Teber, B Hadaschik, S Pahernik, M Hohenfellner
PURPOSE: The purpose of this study is to investigate the safety and patients' benefit of incidental appendectomy during robot-assisted laparoscopic radical prostatectomy (RALRP). METHODS: Fifty-three patients, who had incidental appendectomy during RALRP between January 2012 and March 2014, were enrolled to this study. To evaluate the safety of the procedure, following parameters were evaluated: patient age, duration of surgery, perioperative complications (classified by Clavien-Dindo), time to bowel movement, and length of hospital stay...
November 2, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29070005/cecal-endometriosis-with-intestinal-metaplasia-misdiagnosed-as-neoplasm-of-the-cecum-by-intraoperative-histological-examination
#17
Xinge Fu, Juhong Jiang, Bin Li, Xiao-Ying Tian, Zhi Li
Appendiceal or cecal endometriosis with intestinal metaplasia is uncommon and may mimic mucinous tumors of the appendix. A 50-year-old woman was found incidentally to have an ileocecal lesion. In the intraoperative histological examination, a diagnosis of neoplasm of the cecum was made predominantly based on mucin extrusion with scattered lining mucinous epithelium. However, postoperative histological diagnosis of the lesion was cecal endometriosis with intestinal metaplasia as determined by thoroughly microscopic inspection and the presence of typical endometrial glands with surrounding endometrial-type stroma...
February 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29016471/an-update-on-the-diagnosis-grading-and-staging-of-appendiceal-mucinous-neoplasms
#18
Mark A Valasek, Reetesh K Pai
Despite advances in our understanding of appendiceal mucinous neoplasms and their relationship to the pseudomyxoma peritonei syndrome, the classification of mucinous tumors of the appendix is still confusing. This review will provide an update on the various classification systems that have been recently proposed for appendiceal mucinous neoplasia, with a particular emphasis on how to handle and report the histologic findings for these tumors using the newly published Peritoneal Surface Oncology Group International (PSOGI) and American Joint Committee on Cancer (AJCC) eighth edition guidelines...
January 2018: Advances in Anatomic Pathology
https://www.readbyqxmd.com/read/28993033/ca-19-9-to-peritoneal-carcinomatosis-index-pci-ratio-is-prognostic-in-patients-with-epithelial-appendiceal-mucinous-neoplasms-and-peritoneal-dissemination-undergoing-cytoreduction-surgery-and-intraperitoneal-chemotherapy-a-retrospective-cohort-study
#19
Mathew A Kozman, Oliver M Fisher, Bree-Anne J Rebolledo, Sarah J Valle, Nayef Alzahrani, Winston Liauw, David L Morris
BACKGROUND: Serum tumour levels have been shown to be prognostic in patients with epithelial appendiceal mucinous neoplasms with peritoneal dissemination (pseudomyxoma peritonei (PMP)). A singular index which incorporates both tumour activity (as depicted by serum tumour marker levels) and tumour volume (as depicted by peritoneal carcinomatosis index (PCI)), may give a more precise surrogate of tumour biological behaviour. The prognostic implication of this index has not yet been reported...
December 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28988021/two-concurrent-appendiceal-neoplasms-in-an-elderly-patient-a-case-report
#20
Riva Das, Joshua P Cantor, Thai Q Vu
INTRODUCTION: Acute appendicitis, one of the commonest surgical diagnoses, is rare and more complex presentation in the elderly. Physicians must consider atypical causes appendicitis in this population, which could affect the management of the patient. PRESENTATION OF CASE: An elderly female presented with a two-day history of lower abdominal pain, associated with low-grade fevers and chills. Studies showed leukocytosis and computed tomography (CT) findings consistent with appendicitis...
2017: International Journal of Surgery Case Reports
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