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https://www.readbyqxmd.com/read/28219725/planar-implantable-sensor-for-in-vivo-measurement-of-cellular-oxygen-metabolism-in-brain-tissue
#1
Vassiliy Tsytsarev, Fatih Akkenti, Elena Pumbo, Qinggong Tang, Yu Chen, Reha S Erzurumlu, Dmitri B Papkovsky
BACKGROUND: Brain imaging methods are continually improving. Imaging of the cerebral cortex is widely used in both animal experiments and charting human brain function in health and disease. Among the animal models, the rodent cerebral cortex has been widely used because of patterned neural representation of the whiskers on the snout and relative ease of activating cortical tissue with whisker stimulation. NEW METHOD: We tested a new planar solid-state oxygen sensor comprising a polymeric film with a phosphorescent oxygen-sensitive coating on the working side, to monitor dynamics of oxygen metabolism in the cerebral cortex following sensory stimulation...
February 17, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28215387/dissemination-of-technology-to-evaluate-healthy-food-incentive-programs
#2
Darcy A Freedman, Alan R Hunt, Katie Merritt, En-Jung Shon, Stephanie N Pike
INTRODUCTION: Federal policy supports increased implementation of monetary incentive interventions for chronic disease prevention among low-income populations. This study describes how a Prevention Research Center, working with a dissemination partner, developed and distributed technology to support nationwide implementation and evaluation of healthy food incentive programming focused on Supplemental Nutrition Assistance Program recipients. METHODS: FM Tracks, an iOS-based application and website, was developed to standardize evaluation methods for healthy food incentive program implementation at direct-to-consumer markets...
March 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28197800/small-airway-obstruction-in-chronic-obstructive-pulmonary-disease-potential-parameters-for-early-detection
#3
Tomasz Piorunek, Magdalena Kostrzewska, Marta Stelmach-Mardas, Marcin Mardas, Sławomir Michalak, Joanna Goździk-Spychalska, Halina Batura-Gabryel
The impulse oscillometry (IOS) is recognized as a complementary method to spirometry in the diagnostics of obstructive pulmonary disorders. The IOS enables to measure total respiratory resistance (R5) and proximal respiratory resistance (R20), with the R5-R20 difference reflecting small airway resistance. This study seeks to evaluate the usefulness of R5-R20, maximal mid-expiratory flow (MMEF), and forced expiratory volume in 3 s/forced vital capacity ratio (FEV3/FVC), in the assessment of small airway obstruction in chronic obstructive pulmonary disease (COPD)...
February 15, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28168609/a-comparison-of-the-characteristics-of-ios-and-android-users-of-a-smoking-cessation-app
#4
Harveen Kaur Ubhi, Daniel Kotz, Susan Michie, Onno C P van Schayck, Robert West
iOS and Android smartphone users may differ in ways that affect their use and likelihood of success when using a smoking cessation application (app). If so, it may be necessary to take the device type (iOS and Android) into account when designing smoking cessation apps and in studies evaluating app effectiveness. How do socio-demographic and smoking characteristics, potentially relevant to engagement and cessation outcomes, of the SF28 app users differ between those using the iOS version and those using the Android version? Data were collected between October 2013 and April 2015...
February 6, 2017: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/28164839/apps-for-radiation-oncology-a-comprehensive-review
#5
REVIEW
J J Calero, L F Oton, C A Oton
INTRODUCTION: Software applications executed on a smart-phone or mobile device ("Apps") are increasingly used by oncologists in their daily work. A comprehensive critical review was conducted on Apps specifically designed for Radiation Oncology, which aims to provide scientific support for these tools and to guide users in choosing the most suited to their needs. MATERIAL AND METHODS: A systematic search was conducted in mobile platforms, iOS and Android, returning 157 Apps...
February 2017: Translational Oncology
https://www.readbyqxmd.com/read/28163346/in-vivo-intrinsic-optical-signal-imaging-of-mouse-retinas
#6
Benquan Wang, Xincheng Yao
Intrinsic optical signal (IOS) imaging is a promising noninvasive method for advanced study and diagnosis of eye diseases. Before pursuing clinical applications, more IOS studies employing animal models are necessary to establish the relationship between IOS distortions and eye diseases. Ample mouse models are available for investigating the relationship between IOS distortions and eye diseases. However, in vivo IOS imaging of mouse retinas is challenging due to the small ocular lens (compared to frog eyes) and inevitable eye movements...
February 13, 2016: Proceedings of SPIE
https://www.readbyqxmd.com/read/28145859/phytochemical-properties-of-iranian-organic-saffron-stigma-antioxidant-anticancer-and-apoptotic-approaches
#7
M A Behdani, R Hoshyar
Agronomic and environmental factors affect quality and quantity of constituents in Saffron.  In this study, we compared chemical and antioxidant compounds of organic (OS) and inorganic (IOS) stigma of saffron and evaluated their anti-proliferative and apoptosis effects on cancer cells. Total antioxidant capacity of both saffron were characterized by FRAP, DPPH and Folin-Ciocalteu. HPLC and MTT methods were used to assay the amount of their secondary metabolites and anticancer effects, respectively. The expression of two apoptosis-related genes in treated cells evaluated by quantitative Real Time-PCR analysis...
December 30, 2016: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28140766/connected-cane-tactile-button-input-for-controlling-gestures-of-ios-voiceover-embedded-in-a-white-cane
#8
Jared M Batterman, Vincent F Martin, Derek Yeung, Bruce N Walker
Accessibility of assistive consumer devices is an emerging research area with potential to benefit both users with and without visual impairments. In this article, we discuss the research and evaluation of using a tactile button interface to control an iOS device's native VoiceOver Gesture navigations (Apple Accessibility, 2014). This research effort identified potential safety and accessibility issues for users trying to interact and control their touchscreen mobile iOS devices while traveling independently...
January 31, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28129625/upregulation-of-the-long-non-coding-rna-spry4-it1-indicates-a-poor-prognosis-and-promotes-tumorigenesis-in-ovarian-cancer
#9
Hongxia Li, Chunhua Liu, Zhanbin Lu, Li Chen, Juan Wang, Yindi Li, Huiping Ma
Long non-coding RNAs (lncRNAs) have been identified to be critical mediators in various tumors associated with cancer progression. LncRNA SPRY4-IT1 serves as a novel prognostic biomarker for hepatocellular carcinoma. However, the biological role and clinical significance of lncRNA SPRY4-IT1 in human ovarian cancer (OC) need to be completely elucidated. The aim of the present study was to explore the lncRNA SPRY4-IT1 expression in human OC patients and its role in OC cells. We show that lncRNA SPRY4-IT1 expression is significantly upregulated in ovarian tumor tissues and OC cell lines in comparison with adjacent non-tumor control tissues and the human ovarian immortalized nontumorigenic ovarian surface epithelial (IOSE), respectively...
January 24, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28125985/consensus-on-draft-omeract-core-domains-for-clinical-trials-of-total-joint-replacement-outcome-by-orthopaedic-surgeons-a-report-from-the-international-consensus-on-outcome-measures-in-tjr-trials-i-comitt-group
#10
Jasvinder A Singh, Michael Dohm, Peter F Choong
BACKGROUND: There are no core outcome domain or measurement sets for Total Joint Replacement (TJR) clinical trials. Our objective was to achieve an International consensus by orthopaedic surgeons on the OMERACT core domain/area set for TJR clinical trials. METHODS: We conducted surveys of two orthopaedic surgeon cohorts, which included (1) the leadership of international orthopaedic societies and surgeons (IOS; cohort 1), and (2) the members of the American Academy of Orthopaedic Surgeons' Outcome Special Interest Group (AAOS-Outcome SIG), and/or the Outcome Research Interest Group of the Orthopaedic Research Society (ORS; cohort 2)...
January 26, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28118917/opening-the-duke-electronic-health-record-to-apps-implementing-smart-on-fhir
#11
Richard A Bloomfield, Felipe Polo-Wood, Joshua C Mandel, Kenneth D Mandl
OBJECTIVE: Recognizing a need for our EHR to be highly interoperable, our team at Duke Health enabled our Epic-based electronic health record to be compatible with the Boston Children's project called Substitutable Medical Apps and Reusable Technologies (SMART), which employed Health Level Seven International's (HL7) Fast Healthcare Interoperability Resources (FHIR), commonly known as SMART on FHIR. METHODS: We created a custom SMART on FHIR-compatible server infrastructure written in Node...
March 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28108790/-treatment-of-supine-position-related-obstructive-sleep-apnea-with-smartphone-applications
#12
D Haas, R Birk, J T Maurer, K Hörmann, B A Stuck, J U Sommer
BACKGROUND: Positional obstructive sleep apnea (POSA) is common in mild and moderate forms of obstructive sleep apnea (OSA). Two smartphone applications (apps) professing to avoid the supine position (SP) are available: for Android the "Apnea Sleep Position Trainer" and for iOS the "SomnoPose-Sleep Position Monitor". The smartphone needs to be attached to the chest to recognize SP, which then triggers a vibration alarm. This is intended to encourage the patient to change position and the vibration stops as soon as SP is left...
January 20, 2017: HNO
https://www.readbyqxmd.com/read/28106832/plaimos-a-remote-mobile-healthcare-platform-to-monitor-cardiovascular-and-respiratory-variables
#13
Ramses Miramontes, Raúl Aquino, Arturo Flores, Guillermo Rodríguez, Rafael Anguiano, Arturo Ríos, Arthur Edwards
The number of elderly and chronically ill patients has grown significantly over the past few decades as life expectancy has increased worldwide, leading to increased demands on the health care system and significantly taxing traditional health care practices. Consequently, there is an urgent need to use technology to innovate and more constantly and intensely monitor, report and analyze critical patient physiological parameters beyond conventional clinical settings in a more efficient and cost effective manner...
January 19, 2017: Sensors
https://www.readbyqxmd.com/read/28102532/time-to-epinephrine-in-out-of-hospital-cardiac-arrest-a-retrospective-analysis-of-intraosseous-versus-intravenous-access
#14
Elliot M Ross, Julian Mapp, Chetan Kharod, David A Wampler, Christopher Velasquez, David A Miramontes
INTRODUCTION: The 2015 advanced cardiac life support update continues to advocate administering epinephrine during cardiac arrest. The goal of our study is to determine if prehospital intraosseous (IO) access results in shorter time to epinephrine than prehospital peripheral intravenous (PIV) access. METHODS: The out-of-hospital cardiac arrest (OHCA) database of a large, urban, fire-based emergency medical services system was searched for consecutive cases of OHCA between January 2013 and December 2015...
April 2016: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28093860/monolithic-implant-supported-lithium-disilicate-ls2-crowns-in-a-complete-digital-workflow-a-prospective-clinical-trial-with-a-2-year-follow-up
#15
Tim Joda, Marco Ferrari, Urs Brägger
BACKGROUND: The technical development of digital processing allows the production of anatomically full-contoured implant-supported restorations. PURPOSE: The aim of this prospective clinical trial was to analyze the treatment concept of monolithic lithium disilicate (LS2) single-unit restorations in a complete digital workflow. MATERIAL AND METHODS: Forty-four patients were restored with 50 screw-retained monolithic implant LS2 crowns bonded to pre-fabricated titanium abutments on soft tissue level implants (Institut Straumann AG, Basel, Switzerland) in premolar and molar sites...
January 16, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28072463/pilot-study-of-mobile-phone-technology-in-allergic-rhinitis-in-european-countries-the-mask-rhinitis-study
#16
J Bousquet, D P Caimmi, A Bedbrook, M Bewick, P W Hellings, P Devillier, S Arnavielhe, C Bachert, K C Bergmann, G W Canonica, N Chavannes, A A Cruz, R Dahl, P Demoly, G De Vries, E Mathieu-Dupas, A Fink Wagner, J Fonseca, N Guldemond, T Haahtela, B Hellqvist-Dahl, J Just, T Keil, L Klimek, M L Kowalski, M Kuitunen, P Kuna, V Kvedariene, D Laune, A M Pereira, P Carreiro-Martins, E Melén, M Morais-Almeida, J Mullol, A Muraro, R Murray, L Nogueira-Silva, N G Papadopoulos, G Passalacqua, F Portejoie, D Price, D Ryan, B Samolinski, A Sheikh, V Siroux, O Spranger, A Todo Bom, P V Tomazic, A Valero, E Valovirta, A Valiulis, O VandenPlas, S van der Meulen, M van Eerd, M Wickman, T Zuberbier
BACKGROUND: The use of Apps running on smartphones and tablets profoundly affects medicine. The MASK-rhinitis (MACVIA-ARIA Sentinel NetworK for allergic rhinitis) App (Allergy Diary) assesses allergic rhinitis symptoms, disease control and impact on patients' lives. It is freely available in 20 countries (iOS and Android platforms). AIMS: To assess in a pilot study whether (i) Allergy Diary users were able to properly provide baseline characteristics (ii) simple phenotypic characteristics based upon data captured by the Allergy Diary could be identified and (iii) information gathered by this study could suggest novel research questions...
January 10, 2017: Allergy
https://www.readbyqxmd.com/read/28067287/smartphone-based-low-light-detection-for-bioluminescence-application
#17
Huisung Kim, Youngkee Jung, Iyll-Joon Doh, Roxana Andrea Lozano-Mahecha, Bruce Applegate, Euiwon Bae
We report a smartphone-based device and associated imaging-processing algorithm to maximize the sensitivity of standard smartphone cameras, that can detect the presence of single-digit pW of radiant flux intensity. The proposed hardware and software, called bioluminescent-based analyte quantitation by smartphone (BAQS), provides an opportunity for onsite analysis and quantitation of luminescent signals from biological and non-biological sensing elements which emit photons in response to an analyte. A simple cradle that houses the smartphone, sample tube, and collection lens supports the measuring platform, while noise reduction by ensemble averaging simultaneously lowers the background and enhances the signal from emitted photons...
January 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28065896/ge-mini-a-mobile-app-for-large-scale-gene-expression-visualization
#18
Zefang Tang, Chenwei Li, Karena Zhang, Mingyu Yang, Xueda Hu
: The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) projects produced large-scale RNA sequencing data, which provides an opportunity for performing integrated expression analysis for all genes across tens of thousands of tumor and normal tissue specimens. Rapid access to and easy visualization of such valuable data could facilitate research in a wide biological area. Here, we present the GE-mini APP for smart phones, a mobile visualization tool for integrated gene expression data based on both TCGA and GTEx...
January 8, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28018210/measuring-the-moment-to-moment-variability-of-tinnitus-the-trackyourtinnitus-smart-phone-app
#19
Winfried Schlee, Rüdiger C Pryss, Thomas Probst, Johannes Schobel, Alexander Bachmeier, Manfred Reichert, Berthold Langguth
Tinnitus, the phantom perception of sound without a corresponding external sound, is a frequent disorder which causes significant morbidity. So far there is no treatment available that reliably reduces the tinnitus perception. The research is hampered by the large heterogeneity of tinnitus and the fact that the tinnitus perception fluctuates over time. It is therefore necessary to develop tools for measuring fluctuations of tinnitus perception over time and for analyzing data on single subject basis. However, this type of longitudinal measurement is difficult to perform using the traditional research methods such as paper-and-pencil questionnaires or clinical interviews...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28012017/surgical-exploration-in-persistent-inferior-oblique-overactions
#20
Feray Koc
PURPOSE: To report the causes of persistent inferior oblique (IO) overactions after disinsertion procedure. METHODS: Surgical findings of nine eyes of eight patients who needed secondary surgery to the IO muscles because of persistent overaction after IO disinsertion were evaluated retrospectively. Inferior obliques were found partially retracted into their sheath, and some parts of the proximal muscle stumps were found to have established attachments through scar tissues to the sclera in five eyes...
December 24, 2016: International Ophthalmology
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