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Visceral pain

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https://www.readbyqxmd.com/read/28727709/transforaminal-percutaneous-endoscopic-discectomy-and-foraminoplasty-after-lumbar-spinal-fusion-surgery
#1
Jian-Jun Wu, Hui-Zhen Chen, Changkun Zheng
BACKGROUND: The most common causes of pain following lumbar spinal fusions are residual herniation, or foraminal fibrosis and foraminal stenosis that is ignored, untreated, or undertreated. The original surgeon may advise his patient that nothing more can be done in his opinion that the nerve was visually decompressed by the original surgery. Post-operative imaging or electrophysiological assessment may be inadequate to explain all the reasons for residual or recurrent symptoms. Treatment of failed lumbar spinal fusions by repeat traditional open revision surgery usually incorporates more extensive decompression causing increased instability and back pain...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28701860/noradrenaline-serotonin-gaba-and-glycine-in-cerebrospinal-fluid-during-labor-pain-a-cross-sectional-prospective-study
#2
Pornpan Chalermkitpanit, Atikun Thonnagith, Phatthanaphol Engsusophon, Somrat Charuluxananan, Sittisak Honsawek
BACKGROUND AND AIMS: The inhibitory pathways that play a role in spinal modulation include local interneurons and descending control. Clinical data regarding the role of these pathways in acute pain is lacking. Accordingly, the aim of this study was to evaluate cerebrospinal fluid (CSF) levels of noradrenaline, serotonin, gamma-aminobutyric acid (GABA), and glycine in parturients with labor pain compared to those without labor pain. METHODS: One hundred term uncomplicated pregnant women receiving spinal anesthesia for cesarean section were enrolled in this prospective cross-sectional study...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/28700339/trypsin-protease-activated-receptor-2-signaling-contributes-to-pancreatic-cancer-pain
#3
Jiao Zhu, Xue-Rong Miao, Kun-Ming Tao, Hai Zhu, Zhi-Yun Liu, Da-Wei Yu, Qian-Bo Chen, Hai-Bo Qiu, Zhi-Jie Lu
Pain treatment is a critical aspect of pancreatic cancer patient clinical care. This study investigated the role of trypsin-protease activated receptor-2 (PAR-2) in pancreatic cancer pain. Pancreatic tissue samples were collected from pancreatic cancer (n=22) and control patients (n=22). Immunofluorescence analyses confirmed colocalization of PAR-2 and neuronal markers in pancreatic cancer tissues. Trypsin levels and protease activities were higher in pancreatic cancer tissue specimens than in the controls...
June 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28696855/don-t-forget-the-abdominal-wall-imaging-spectrum-of-abdominal-wall-injuries-after-nonpenetrating-trauma
#4
Shanna A Matalon, Reza Askari, Jonathan D Gates, Ketan Patel, Aaron D Sodickson, Bharti Khurana
Abdominal wall injuries occur in nearly one of 10 patients coming to the emergency department after nonpenetrating trauma. Injuries range from minor, such as abdominal wall contusion, to severe, such as abdominal wall rupture with evisceration of abdominal contents. Examples of specific injuries that can be detected at cross-sectional imaging include abdominal muscle strain, tear, or hematoma, including rectus sheath hematoma (RSH); traumatic abdominal wall hernia (TAWH); and Morel-Lavallée lesion (MLL) (closed degloving injury)...
July 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28695708/targeting-fatty-acid-amide-hydrolase-and-transient-receptor-potential-vanilloid-1-simultaneously-to-modulate-colonic-motility-and-visceral-sensation-in-the-mouse-a-pharmacological-intervention-with-n-arachidonoyl-serotonin-aa-5-ht
#5
M Bashashati, J Fichna, F Piscitelli, R Capasso, A A Izzo, A Sibaev, J-P Timmermans, N Cenac, N Vergnolle, V Di Marzo, M Storr
BACKGROUND: Endocannabinoid anandamide (AEA) inhibits intestinal motility and visceral pain, but it may also be proalgesic through transient receptor potential vanilloid-1 (TRPV1). AEA is degraded by fatty acid amide hydrolase (FAAH). This study explored whether dual inhibition of FAAH and TRPV1 reduces diarrhea and abdominal pain. METHODS: Immunostaining was performed on myenteric plexus of the mouse colon. The effects of the dual FAAH/TRPV1 inhibitor AA-5-HT on electrically induced contractility, excitatory junction potential (EJP) and fast (f) and slow (s) inhibitory junction potentials (IJP) in the mouse colon, colonic propulsion and visceromotor response (VMR) to rectal distension were studied...
July 11, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28690772/bladder-urothelial-carcinoma-extending-to-rectal-mucosa-and-presenting-with-rectal-bleeding
#6
Andrew M Aneese, Vinayata Manuballa, Mitual Amin, Mitchell S Cappell
An 87-year-old-man with prostate-cancer-stage-T1c-Gleason-6 treated with radiotherapy in 1996, recurrent prostate cancer treated with leuprolide hormonal therapy in 2009, and bladder-urothelial-carcinoma in situ treated with Bacillus-Calmette-Guerin and adriamycin in 2010, presented in 2015 with painless, bright red blood per rectum coating stools daily for 5 mo. Rectal examination revealed bright red blood per rectum; and a hard, fixed, 2.5 cm × 2.5 cm mass at the normal prostate location. The hemoglobin was 7...
June 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28687502/endovascular-treatment-of-distal-tears-located-in-the-reno-viseceral-segment-with-bare-metal-stents-and-coils-in-a-complicated-type-b-aortic-dissection
#7
Qingsheng Lu, Yanqing Chen, Yongxue Zhang, Hongfei Wang, Hanyan Li, Jiaxuan Feng, Huajuan Mao, Zaiping Jing
PURPOSE: To provide an endovascular strategy of treating patent re-entries adjacent to visceral branches in the management of aortic dissections. CASE REPORT: A 45-year-old male who had received endovascular treatment for a type B aortic dissection was again admitted for his intermittent abdominal pain. Distal tears located in the reno-visceral segment was left untreated in the initial procedure, and was thought to be related to the expansion of the false lumen during follow-up...
July 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28683025/visceral-pain-as-a-triggering-factor-for-fibromyalgia-symptoms-in-comorbid-patients
#8
Raffaele Costantini, Giannapia Affaitati, Ursula Wesselmann, Peter Czakanski, Maria Adele Giamberardino
Fibromyalgia (FMS) is a central sensitization syndrome, however peripheral pain sources potentially exacerbate its symptoms of chronic diffuse musculoskeletal pain and hyperalgesia. This prospective study evaluated visceral pain as a possible triggering factor for FMS pain/hyperalgesia in comorbid patients. Women with: a) FMS+irritable bowel syndrome (IBS); b) FMS+primary dysmenorrhea (Dys); c) FMS+dysmenorrhea secondary to endometriosis (Endo); d) FMS+colon diverticulosis (Div) were compared with FMS-only women, for fibromyalgia pain (number/intensity of episodes, analgesic consumption) over comparable time periods and for somatic hyperalgesia (electrical/pressure pain thresholds) in painful (Tender Points, TePs) and control areas (trapezius, deltoid, quadriceps muscles and overlying subcutis and skin)...
July 3, 2017: Pain
https://www.readbyqxmd.com/read/28677871/well-leg-compartment-syndrome-after-laparoscopic-low-anterior-resection-for-lower-rectal-cancer-in-the-lithotomy-position-a-case-report
#9
Masaya Nishino, Miho Okano, Junji Kawada, Yongkook Kim, Mami Yamada, Toshimasa Tsujinaka
A 64-year-old man underwent laparoscopic low anterior resection for lower rectal cancer. Because he was overweight (BMI, 28.1 kg/m(2) ) with rich visceral fat and a narrow pelvic cavity, the operation was technically difficult and the operation time was 686 min. Postoperatively, the patient immediately complained of pain and swelling of the left lower limb. Laboratory examination showed that serum creatinine kinase was markedly increased and urine myoglobin was positive on postoperative day 1. He was diagnosed with well-leg compartment syndrome and was transported to the trauma and critical care center for emergency fasciotomy...
July 5, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28676362/musculoskeletal-approach-to-pelvic-pain
#10
REVIEW
Kate E Temme, Jason Pan
Visceral and somatic causes of pelvic pain are often inter-related, and a musculoskeletal examination should always be considered for the successful diagnosis and treatment of pelvic pain. For the diverse etiologies of hip pain, there are many unique considerations for the diagnosis and treatment of these various disorders. Pelvic pain is often multidimensional due to the overlap between lumbo-hip-pelvic diagnoses and may require a multidisciplinary approach to evaluation and management.
August 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/28675524/biomarkers-for-visceral-hypersensitivity-in-patients-with-irritable-bowel-syndrome
#11
Z Mujagic, D M A E Jonkers, S Ludidi, D Keszthelyi, M A Hesselink, Z Z R M Weerts, R N Kievit, J F Althof, C Leue, J W Kruimel, F J van Schooten, A A M Masclee
BACKGROUND: Increased visceral sensitivity is observed in up to 60% of patients with Irritable Bowel Syndrome (IBS). Mucosal inflammation, altered neuroendocrine activity and intraluminal metabolic processes may contribute to the development of visceral hypersensitivity. Previously, we demonstrated that biomarkers, indicative for these biological processes, were altered in IBS patients compared to healthy controls. However, how these processes relate to visceral hypersensitivity is unknown...
July 3, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28666812/single-agent-oral-vinorelbine-as-first-line-chemotherapy-for-endocrine-pretreated-breast-cancer-with-bone-metastases-and-no-visceral-involvement-norbreast-228-phase-ii-study
#12
Guenther G Steger, Adriana Dominguez, Natalia Dobrovolskaya, Francesco Giotta, Nicole Tubiana-Mathieu, Martin Pecherstorfer, Antonio Ardizzoia, Maria Blasinska-Morawiec, Enrique Espinosa, Gustavo Villanova
PURPOSE: Single-agent oral chemotherapy is widely used in patients with bone metastases without visceral involvement, especially in hormone receptor-positive metastatic breast cancer (mBC). However, this option has been poorly evaluated in clinical trials. METHODS: Eligible patients had mBC with predominantly bone but not visceral metastases, were receiving bisphosphonate therapy, and had previously received endocrine therapy (any setting) but not chemotherapy for mBC...
June 27, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28665377/-the-novel-approaches-to-the-rehabilitation-of-the-patients-presenting-with-gastroesophageal-reflux-disease-and-co-morbid-pathology
#13
N E Komleva, A A Marjanovsky, A N Danilov, L G Agasarov
This paper was designed to discuss the problems of co-morbidity and approaches to the rehabilitation of the patients presenting with gastroesophageal reflux disease and a concomitant pathology and to analyze the issues concerning the possible vertebro-visceral correlations inherent in the diseases of the internal organs. AIM: To evaluate the vertebro-neurological status of the thoracic segment of the vertebral column in the patients suffering from gastroesophageal reflux disease and to further improve the methods for their treatment taking into consideration the concomitant pathology, if any...
2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/28660823/glisson-s-capsule-cauterisation-is-associated-with-increased-postoperative-pain-after-laparoscopic-cholecystectomy-a-prospective-case-control-study
#14
F Basak, M Hasbahceci, A Sisik, A Acar, Y Ozel, T Canbak, M Yucel, F Ezberci, G Bas
INTRODUCTION Postoperative pain after laparoscopic cholecystectomy has three components: parietal, visceral and referred pain felt at the shoulder. Visceral peritoneal injury on the liver (Glisson's capsule) during cauterisation sometimes occurs as an unavoidable complication of the operation. Its effect on postoperative pain has not been quantified. In this study, we aimed to evaluate the association between Glisson's capsule injury and postoperative pain following laparoscopic cholecystectomy. METHODS The study was a prospective case-control of planned standard laparoscopic cholecystectomy with standardized anaesthesia protocol in patients with benign gallbladder disease...
July 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28660464/respiratory-tract-infection-caused-by-fonsecaea-monophora-after-kidney-transplantation
#15
Isabella Barbosa Cleinman, Sarah Santos Gonçalves, Marcio Nucci, Danielle Carvalho Quintella, Márcia Halpern, Tiyomi Akiti, Glória Barreiros, Arnaldo Lopes Colombo, Guilherme Santoro-Lopes
Fonsecaea spp. are melanized fungi which cause most cases of chromoblastomycosis. The taxonomy of this genus has been revised, now encompassing four species, with different pathogenic potential: F. pedrosoi, F. nubica, F. pugnacius, and F. monophora. The latter two species present wider clinical spectrum and have been associated with cases of visceral infection, most often affecting the brain. To our knowledge, this is the first report of proven case of F. monophora respiratory tract infection. A Brazilian 57-year-old-female patient underwent kidney transplantation on January 12, 2013...
June 28, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28658164/the-analgesic-efficacy-of-oxycodone-hydrochloride-versus-fentanyl-during-outpatient-artificial-abortion-operation-a-randomized-trial
#16
RANDOMIZED CONTROLLED TRIAL
Kangjie Xie, Wen Zhang, Wumei Fang, Yanhong Lian, Sufeng Lin, Jun Fang
BACKGROUND: Problems like body movement, respiratory depression, and complained of pain are still common phenomenon in outpatient artificial abortion general anesthesia. Oxycodone hydrochloride is a semisynthetic opioid and has a good therapeutic effect on visceral pain. We hypothesize that oxycodone hydrochloride would be superior to fentanyl in outpatient artificial abortion surgery. METHODS: In this clinical trial 149 American Society of Anesthesiologists (ASA) I or II female outpatients scheduled for elective artificial abortion surgeries under general anesthesia were randomly divided into 3 groups: oxycodone hydrochloride 0...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28654824/visceral-sensitivity-anxiety-and-smoking-among-treatment-seeking-smokers
#17
Michael J Zvolensky, Jafar Bakhshaie, Peter J Norton, Jasper A J Smits, Julia D Buckner, Lorra Garey, Kara Manning
It is widely recognized that smoking is related to abdominal pain and discomfort, as well as gastrointestinal disorders. Research has shown that visceral sensitivity, experiencing anxiety around gastrointestinal sensations, is associated with poorer gastrointestinal health and related health outcomes. Visceral sensitivity also increases anxiety symptoms and mediates the relation with other risk factors, including gastrointestinal distress. No work to date, however, has evaluated visceral sensitivity in the context of smoking despite the strong association between smoking and poor physical and mental health...
June 20, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28653374/a-familial-mediterranean-fever-flare-induced-by-a-drug-reaction-with-eosinophilia-and-systemic-symptoms
#18
A Deschamps, A Samain, P Carvalho, P Courville, H Levesque, P Musette, P Joly
Familial Mediterranean Fever (FMF) is an autosomal recessive inherited auto-inflammatory disease revealed by flare episodes characterized by systemic symptoms (pleural, joint serositis, abdominal pain…) that are triggered by infections, cold or menstruations. Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a severe cutaneous adverse reaction characterized by visceral involvement and viral reactivation including HHV6, HHV7, EBV, CMV… and may be associated with certain HLA alleles. This article is protected by copyright...
June 27, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28649695/neuronal-aromatase-expression-in-pain-processing-regions-of-the-medullary-and-spinal-cord-dorsal-horn
#19
May Tran, Julia A Kuhn, João M Bráz, Allan I Basbaum
In both acute and chronic pain conditions, women tend to be more sensitive than men. This sex difference may be regulated by estrogens, such as estradiol, that are synthesized in the spinal cord and brainstem and act locally to influence pain processing. To identify a potential cellular source of local estrogen, here we examined the expression of aromatase, the enzyme that catalyzes the conversion of testosterone to estradiol. Our studies focused on primary afferent neurons and on their central targets in the spinal cord and medulla as well as in the nucleus of the solitary tract, the target of nodose ganglion-derived visceral afferents...
June 26, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28644200/electrical-stimulations-of-the-human-insula-their-contribution-to-the-ictal-semiology-of-insular-seizures
#20
Laure Mazzola, François Mauguière, Jean Isnard
INTRODUCTION: Stereotactic stimulations of the insular cortex through intracranial electrodes aim at characterizing the semiology of insular seizures. These stimulations, carried out in the context of Stereo-Electro-Encephalography (SEEG) during presurgical monitoring of epilepsy, reproduce the ictal symptoms observed during the development of insular seizures. METHODS: The authors reviewed the results of insular stimulations performed in 222 patients admitted between 1997 and 2015 for presurgical SEEG exploration of atypical temporal or perisylvian epilepsy...
July 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
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