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https://www.readbyqxmd.com/read/29054122/assessing-the-reporting-quality-of-influenza-outbreaks-in-the-community
#1
Calvin Lo, Dominik Mertz, Mark Loeb
BACKGROUND: High quality reporting of outbreak characteristics is fundamental to understand the behavior of various strains of influenza virus and the impact of outbreak management strategies. However, few studies have systematically evaluated the quality of outbreak reporting. OBJECTIVES: To conduct a systematic analysis and assessment for reporting quality of influenza outbreaks based on a modified version of the STROBE statement, and to examine characteristics associated with reporting quality...
October 20, 2017: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/29054113/post-operative-corticosteroid-irrigation-for-chronic-rhinosinusitis-after-endoscopic-sinus-surgery-a-meta-analysis
#2
Ho Young Yoon, Ho Seok Lee, In Hye Kim, Se Hwan Hwang
BACKGROUND: Recently, topical steroid therapy delivery using high-volume sinonasal irrigations has been used more frequently, following endoscopic sinus surgery (ESS), to improve drug delivery into the paranasal sinuses. OBJECTIVE: The goal of this study was to perform a systematic review with meta-analysis of the efficacy of steroid nasal irrigation on postoperative management of CRS following ESS. METHODS: Five databases (PubMed, SCOPUS, Embase, Web of Science, and the Cochrane database) from inception to March 2017 were independently reviewed by two researchers...
October 20, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29054107/characterization-of-flower-coloration-in-30-rhododendron-species-via-anthocyanin-and-flavonol-identification-and-quantitative-traits
#3
Hui Du, Liming Lai, Fei Wang, Weibang Sun, Lehua Zhang, Xiaohua Li, Liangsheng Wang, Lianhe Jiang, Yuanrun Zheng
• Floral color is a key reproductive character, often associates with environmental adaptation, and undergoes human intervention. A large number of Rhododendron species spread widely with various flower colors, which makes a good model for flower coloration. The chromatic features and anthocyanin compositions of 30 species from seven subgenera were systematically analyzed. • The Royal Horticultural Society Color Chart and CIE L*a*b* system were employed to describe and investigate flower colors. The UPLC-PDA/ESI-MS(n) system was used to identify and quantify anthocyanins in petal extracts...
October 20, 2017: Plant Biology
https://www.readbyqxmd.com/read/29054093/the-role-of-pazopanib-on-tumour-angiogenesis-and-in-the-management-of-cancers-a-review
#4
REVIEW
Dinesh Kumar Chellappan, Jestin Chellian, Zhao Yin Ng, Yan Jinn Sim, Chiu Wei Theng, Joyce Ling, Mei Wong, Jia Hui Foo, Goh Jun Yang, Li Yu Hang, Saranyah Nathan, Yogendra Singh, Gaurav Gupta
Pazopanib is a relatively new compound to be introduced into the chemotherapy field. It is thought to have decent anti-angiogenic properties, which gives an additional hope for the treatment of certain types of cancers. A systematic review solely discussing about pazopanib and its anti-angiogenic effect is yet to be published to date, despite several relevant clinical trials being conducted over the recent years. In this review, we aim to investigate the mechanism of pazopanib's anti-angiogenic effect and its effectiveness in treating several cancers...
October 17, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29054083/modulation-of-valence-band-maximum-edge-and-photocatalytic-activity-of-biox-by-incorporation-of-halides
#5
Jiaxin Lv, Qingsong Hu, Chengjin Cao, Yaping Zhao
To better know the photocatalytic performance of bismuth oxyhalides (BiOX, X = Cl, Br, I) regulated by incorporation of halides within nanostructures, BiOX nanosheets were synthesized through morphology controllable solvothermal method and characterized systematically. The organic structural property greatly influences the photocatalytic activity of BiOX: 1) as for neutral molecular phenol, BiOX shows photocatalytic activity in the order of BiOCl > BiOBr > BiOI under simulated sun light irradiation, and the photo-oxidation kinetics follow Eley-Rideal mechanism; and 2) for adsorbed anionic orange II (OII) and cationic methylene blue (MB), BiOX shows photocatalytic activity in the order of BiOCl > BiOBr > BiOI, and the photo-oxidation kinetics follow Langmuir-Hinshelwood mechanism...
October 1, 2017: Chemosphere
https://www.readbyqxmd.com/read/29054065/investigating-desorption-during-ethanol-elution-to-improve-the-quality-and-antioxidant-activity-of-xylo-oligosaccharides-from-corn-stalk
#6
Jie Zhang, Yue-Hai Wang, Quan-Yuan Wei, Xiao-Jia Du, Yong-Shui Qu
As the most representative of lignocellulosic materials, corn stalk (CS) will be a great candidate to produce xylo-oligosaccharides (XOS). Owing to the high impurity content of the XOS produced by directly enzymatic hydrolysis of xylan extracted from CS, subsequent refining steps are essential. The present study was aimed to investigate desorption during ethanol elution to improve the quality and antioxidant activity of XOS from CS. The desorption was systematically investigated after optimizing the elution conditions...
October 4, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29054043/systematic-approaches-for-targeting-an-atom-probe-tomography-sample-fabricated-in-a-thin-tem-specimen-correlative-structural-chemical-and-3-d-reconstruction-analyses
#7
Sung-Il Baik, Dieter Isheim, David N Seidman
Atom-probe tomography (APT) is a unique analysis tool that enables true three-dimensional (3-D) analyses with sub-nano scale spatial resolution. Recent implementations of the local-electrode atom-probe (LEAP) tomograph with ultraviolet laser pulsing have significantly expanded the research applications of APT. The small field-of-view of a needle-shaped specimen with a less than 100 nm diam. is, however, a major limitation for analyzing materials. The systematic approaches for site-specific targeting of an APT nanotip in a transmission electron microscope (TEM) of a thin sample are introduced to solve the geometrical limitations of a sharpened APT nanotip...
October 12, 2017: Ultramicroscopy
https://www.readbyqxmd.com/read/29054042/spontaneous-hemoperitoneum-in-pregnancy-ship-and-endometriosis-a-systematic-review-of-the-recent-literature
#8
REVIEW
Marit C I Lier, Romana F Malik, Johannes C F Ket, Cornelis B Lambalk, Ivo A Brosens, Velja Mijatovic
Spontaneous Hemoperitoneum in Pregnancy (SHiP), an unprovoked (nontraumatic) intraperitoneal bleeding in pregnancy (up to 42days postpartum), is associated with serious adverse pregnancy outcomes. To evaluate the clinical consequences of SHiP and its association with endometriosis, a systematic review was conducted according to the PRISMA guidelines. PubMed, Embase.com and Thomson Reuters/Web of Science were searched for articles published since the latest review (August 2008) until September 2016. After assessment for eligibility, forty-four articles were included in this systematic review, describing 59 cases of SHiP...
October 12, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29054017/hyperventilation-and-electroconvulsive-therapy-a-literature-review
#9
REVIEW
Jorge Gómez-Arnau, Aida de Arriba-Arnau, Javier Correas-Lauffer, Mikel Urretavizcaya
BACKGROUND: Hyperventilation has been proposed as an augmentation strategy in electroconvulsive therapy (ECT) in accordance with its proconvulsant effect. OBJECTIVE: This study reviews the existing literature on the application of hyperventilation in ECT, its efficacy, and tolerance. METHODS: A systematic search was performed in PubMed and EMBASE databases. Search terms ('electroconvulsive therapy' and 'hyperventilation', 'ventilation', 'hyperoxygenation', 'hyperoxia', 'hypocapnia') were used to retrieve works from 1966 to June 2016...
September 23, 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29053984/ecological-content-validation-of-the-information-assessment-method-for-parents-iam-parent-a-mixed-methods-study
#10
M Bujold, R El Sherif, P L Bush, J Johnson-Lafleur, G Doray, P Pluye
This mixed methods study content validated the Information Assessment Method for parents (IAM-parent) that allows users to systematically rate and comment on online parenting information. Quantitative data and results: 22,407 IAM ratings were collected; of the initial 32 items, descriptive statistics showed that 10 had low relevance. Qualitative data and results: IAM-based comments were collected, and 20 IAM users were interviewed (maximum variation sample); the qualitative data analysis assessed the representativeness of IAM items, and identified items with problematic wording...
October 4, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/29053904/a-direct-aspiration-first-pass-technique-adapt-for-acute-stroke-therapy-a-systematic-review-and-meta-analysis
#11
Benjamin Gory, Xavier Armoiry, Rotem Sivan-Hoffman, Michel Piotin, Mikael Mazighi, Bertrand Lapergue, Raphaël Blanc, Francis Turjman
BACKGROUND AND PURPOSE: ADAPT (A Direct Aspiration First Pass Technique), involving the first-line use of large-bore distal aspiration catheter, is a new strategy in the mechanical thrombectomy of acute ischemic stroke caused by large vessel occlusion. However, its impact on reperfusion rates, clinical outcomes, and complication rates is not fully examined. METHOD: We conducted a systematic review of the literature searching multiple databases for reports on thrombectomy of acute stroke with the ADAPT technique and performed meta-analyses of clinical and radiographic outcomes...
October 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29053903/galectin-3-an-emerging-biomarker-in-stroke-and-cerebrovascular-diseases
#12
Anand Venkatraman, Shalaka Hardas, Nirav Patel, Navkaranbir Singh Bajaj, Garima Arora, Pankaj Arora
BACKGROUND: The carbohydrate-binding molecule Galectin-3 has garnered significant attention recently as a biomarker for various conditions ranging from cardiac disease to obesity. Though there have been several recent studies investigating its role in stroke and other cerebrovascular diseases, awareness of this emerging biomarker in the wider neurology community is limited. METHODS: We performed a systematic search in PubMed, EMBASE, Scopus, CINAHL, Clinicaltrials...
October 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29053901/familial-hypercholesterolaemia-in-patients-with-ischemic-stroke-or-transient-ischemic-attack
#13
Thomas Toell, Lukas Mayer, Raimund Pechlaner, Stefan Krebs, Karin Willeit, Clemens Lang, Christian Boehme, Barbara Prantl, Michael Knoflach, Julia Ferrari, Philipp Fuchs, Wolfgang Prokop, Andrea Griesmacher, Wilfried Lang, Stefan Kiechl, Johann Willeit
BACKGROUND AND AIMS: Identification of patients with familial hypercholesterolemia (FH) is a prerequisite for the appropriate management of their excess cardiovascular risk. It is currently unknown how many patients with acute ischemic stroke or transient ischemic attack (TIA) are affected by FH and whether systematic screening for FH is warranted in these patients. METHODS: The prevalence of a clinical diagnosis of FH was estimated in a large representative series of patients with acute ischemic stroke or TIA (ABCD2 score ≥3) using the Dutch Lipid Clinic Network Algorithm (DLCNA; possible FH ≥3, probable/definite FH ≥6)...
October 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29053873/exercise-for-the-prevention-of-low-back-pain-systematic-review-and-meta-analysis-of-controlled-trials
#14
Rahman Shiri, David Coggon, Kobra Falah-Hassani
The aim of this systematic review and meta-analysis was to assess the effect of exercise in population-based interventions to prevent low back pain (LBP) and associated disability. Comprehensive literature searches were conducted in multiple databases including PubMed, Embase, and Cochrane Library from their inception through June 2017. Thirteen randomized controlled trials and three non-randomized controlled trials qualified for meta-analyses. Exercise alone reduced the risk of LBP by 33% (risk ratio = 0...
October 19, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29053849/a-network-meta-analysis-comparing-effects-of-various-antidepressant-classes-on-the-digit-symbol-substitution-test-dsst-as-a-measure-of-cognitive-dysfunction-in-patients-with-major-depressive-disorder
#15
Bernhard T Baune, Mélanie Brignone, Klaus Groes Larsen
Background: Major depressive disorder (MDD) is a common condition that often includes cognitive dysfunction. A systematic literature review of studies and a network meta-analysis (NMA) were carried out to assess the relative effect of antidepressants on cognitive dysfunction in MDD. Methods: MEDLINE ®, Embase ®, Cochrane, CDSR, PsychINFO ® databases, clinical trial registries, and relevant conference abstracts were searched for randomised controlled trials (RCTs) assessing the effects of antidepressants/placebo on cognition...
October 19, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29053807/systematic-review-of-the-concentrations-of-oligosaccharides-in-human-milk
#16
Stephan Thurl, Manfred Munzert, Günther Boehm, Catherine Matthews, Bernd Stahl
Context: Oligosaccharides are the third largest solid component in human milk. These diverse compounds are thought to have numerous beneficial functions in infants, including protection against infectious diseases. The structures of more than 100 oligosaccharides in human milk have been elucidated so far. Objective: The aim of this review was to identify the main factors that affect the concentrations of oligosaccharides in human milk and to determine whether it is possible to calculate representative and reliable mean concentrations...
October 19, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29053783/systematic-assessment-of-multiple-routine-and-near-real-time-indicators-to-classify-the-severity-of-influenza-seasons-and-pandemics-in-the-united-states-2003-04-through-2015-2016
#17
Matthew Biggerstaff, Krista Kniss, Daniel B Jernigan, Lynnette Brammer, Joseph Bresee, Shikha Garg, Erin Burns, Carrie Reed
Assessments of influenza season severity can guide public health action. We used the Moving Epidemic Method to develop intensity thresholds (IT) for 3 US surveillance indicators from the 2003-04-2014-15 influenza season (excluding the 2009 pandemic): 1) outpatient visits for influenza-like illness, 2) influenza-related hospitalizations, and 3) influenza- and pneumonia-related deaths. ITs were developed for the overall population and children, adults, and older adults separately and were the upper limit of the 50% (IT50), 90% (IT90), and 98% (IT98) one-sided CIs of the geometric mean of each season's 3 highest values...
October 19, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29053759/molecular-dynamic-simulations-reveal-suboptimal-binding-of-salbutamol-in-t164i-variant-of-%C3%AE-2-adrenergic-receptor
#18
Srinivas Bandaru, Mallika Alvala, Anuraj Nayarisseri, Saphy Sharda, Himshikha Goud, Hema Prasad Mundluru, Sanjeev Kumar Singh
The natural variant C491T (rs1800088) in ADRB2 gene substitutes Threonine to Isoleucine at 164th position in β2AR and results in receptor sequestration and altered binding of agonists. Present investigation pursues to identify the effect of T164I variation on function and structure of β2AR through systematic computational approaches. The study, in addition, addresses altered binding of salbutamol in T164I variant through molecular dynamic simulations. Methods involving changes in free energy, solvent accessibility surface area, root mean square deviations and analysis of binding cavity revealed structural perturbations in receptor to incur upon T164I substitution...
2017: PloS One
https://www.readbyqxmd.com/read/29053758/sex-differences-in-long-term-mortality-among-acute-myocardial-infarction-patients-results-from-the-isar-risk-and-art-studies
#19
Romy Ubrich, Petra Barthel, Bernhard Haller, Katerina Hnatkova, Katharina Maria Huster, Alexander Steger, Alexander Müller, Marek Malik, Georg Schmidt
BACKGROUND: Mortality rates in females who survived acute myocardial infarction (AMI) exceed those in males. Differences between sexes in age, cardiovascular risk factors and revascularization therapy have been proposed as possible reasons. OBJECTIVE: To select sets of female and male patients comparable in respect of relevant risk factors in order to compare the sex-specific risk in a systematic manner. METHODS: Data of the ISAR-RISK and ART studies were investigated...
2017: PloS One
https://www.readbyqxmd.com/read/29053744/transition-to-reconstructibility-in-weakly-coupled-networks
#20
Benedict J Lünsmann, Christoph Kirst, Marc Timme
Across scientific disciplines, thresholded pairwise measures of statistical dependence between time series are taken as proxies for the interactions between the dynamical units of a network. Yet such correlation measures often fail to reflect the underlying physical interactions accurately. Here we systematically study the problem of reconstructing direct physical interaction networks from thresholding correlations. We explicate how local common cause and relay structures, heterogeneous in-degrees and non-local structural properties of the network generally hinder reconstructibility...
2017: PloS One
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