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https://www.readbyqxmd.com/read/28814848/pathophysiological-mechanism-of-long-term-noninvasive-ventilation-in-stable-hypercapnic-patients-with-copd-using-functional-respiratory-imaging
#1
Bita Hajian, Jan De Backer, Claire Sneyers, Francisca Ferreira, Katherine C Barboza, Glenn Leemans, Wim Vos, Wilfried De Backer
INTRODUCTION: Patients with severe COPD often develop chronic hypercapnic respiratory failure. Their prognosis worsens and they are more likely to develop exacerbations. This has major influence on the health-related quality of life. Currently, there is no information about the success of long-term noninvasive ventilation (NIV) among patients who receive NIV in acute settings. Also, little is known about the pathophysiological mechanism of NIV. METHODS: Ten Global Initiative for Obstructive Lung Disease stage III and IV COPD patients with respiratory failure who were hospitalized following acute exacerbation were treated with NIV using a Synchrony BiPAP device for 6 months...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28806999/trading-certainty-for-speed-how-much-uncertainty-are-decisionmakers-and-guideline-developers-willing-to-accept-when-using-rapid-reviews-an-international-survey
#2
Gernot Wagner, Barbara Nussbaumer-Streit, Judith Greimel, Agustín Ciapponi, Gerald Gartlehner
BACKGROUND: Decisionmakers and guideline developers demand rapid syntheses of the evidence when time sensitive evidence-informed decisions are required. A potential trade-off of such rapid reviews is that their results can have less reliability than results of systematic reviews that can lead to an increased risk of making incorrect decisions or recommendations. We sought to determine how much incremental uncertainty about the correctness of an answer guideline developers and health policy decisionmakers are willing to accept in exchange for a rapid evidence-synthesis...
August 14, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28799798/abstracts-from-dietetic-research-event-june-8-and-9-2017
#3
(no author information available yet)
St John's, Newfoundland was the host city of the 2017 Dietitians of Canada Annual Conference. Through the support of Dietitians of Canada and CFDR, the 2017 event was both an exciting and informative exchange of research and experience-sharing efforts that inspired attendees. The submissions for this year's Canadian Foundation for Dietetic Research (CFDR) event represented the diversity of dietetic research conducted within Canada. The topics highlighted from this year's abstracts included: Clinical Research; Community-based Nutritional Care; Determinants of Food Choice; Dietary Intake; Dietetic Practice and Education; Food Security; Nutrition and Health Education; Nutritional Assessment and Therapy; Nutrition Attitudes; Nutrition Strategy Development Patient Services; Professional Development; Vulnerable Groups and their Nutritional Needs; and, Wellness and Public Health...
September 2017: Canadian Journal of Dietetic Practice and Research
https://www.readbyqxmd.com/read/28797853/european-association-for-palliative-care-forging-a-vision-of-excellence-in-palliative-care-in-central-and-eastern-european-and-former-sovjet-union-countries-cee-fsu
#4
Lukas Radbruch, Julie Ling, Katalin Hegedus, Philip Larkin
The European Association for Palliative Care (EAPC) represents many thousands of health care workers and volunteers working in or with an interest in palliative care. In 2016, the EAPC has individual members from 48 nations across the world, and collective members from 57 national palliative care associations in 32 European Countries. Throughout its history, the EAPC has produced guidance on a range of palliative care issues. The biennial congresses and research congresses and the comprehensive website (www...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28796578/sharing-sex-secrets-on-facebook-a-content-analysis-of-youth-peer-communication-and-advice-exchange-on-social-media-about-sexual-health-and-intimate-relations
#5
Tien Ee Dominic Yeo, Tsz Hang Chu
Social media present opportunities and challenges for sexual health communication among young people. This study is one of the first to examine the actual use of Facebook for peer communication of sexual health and intimate relations. Content analysis of 2186 anonymous posts in a "sex secrets" Facebook page unofficially affiliated with a Hong Kong University shows gender balance among posters, inclusiveness of sexual minorities, and frequent sharing of personal experiences in storytelling or advice seeking...
August 10, 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/28792514/network-analysis-for-science-and-technology-management-evidence-from-tuberculosis-research-in-fiocruz-brazil
#6
Bruna de Paula Fonseca E Fonseca, Marcus Vinicius Pereira da Silva, Kizi Mendonça de Araújo, Ricardo Barros Sampaio, Milton Ozório Moraes
Collaborative networks are of great value for science and technology (S&T) institutions as a way of sharing, generating and disseminating new knowledge that could ultimately lead to innovations. Driven by the need to assess the contribution and effectiveness of these networks in informing S&T management, we explored the evolution and dynamics of tuberculosis scientific networks involving the Oswaldo Cruz Foundation (Fiocruz), the major public health S&T Institution in Brazil. Social network analysis (SNA) was used to produce a 10-year (2005-2009, 2010-2014) retrospective longitudinal mapping of Brazilian tuberculosis research networks within the country and internationally, highlighting Fiocruz collaborations...
2017: PloS One
https://www.readbyqxmd.com/read/28764728/how-do-stakeholders-from-multiple-hierarchical-levels-of-a-large-provincial-health-system-define-engagement-a-qualitative-study
#7
Jill M Norris, Deborah E White, Lorelli Nowell, Kelly Mrklas, Henry T Stelfox
BACKGROUND: Engaging stakeholders from varied organizational levels is essential to successful healthcare quality improvement. However, engagement has been hard to achieve and to measure across diverse stakeholders. Further, current implementation science models provide little clarity about what engagement means, despite its importance. The aim of this study was to understand how stakeholders of healthcare improvement initiatives defined engagement. METHODS: Participants (n = 86) in this qualitative thematic study were purposively sampled for individual interviews...
August 1, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28760725/what-patients-can-tell-us-topic-analysis-for-social-media-on-breast-cancer
#8
Mike Donald Tapi Nzali, Sandra Bringay, Christian Lavergne, Caroline Mollevi, Thomas Opitz
BACKGROUND: Social media dedicated to health are increasingly used by patients and health professionals. They are rich textual resources with content generated through free exchange between patients. We are proposing a method to tackle the problem of retrieving clinically relevant information from such social media in order to analyze the quality of life of patients with breast cancer. OBJECTIVE: Our aim was to detect the different topics discussed by patients on social media and to relate them to functional and symptomatic dimensions assessed in the internationally standardized self-administered questionnaires used in cancer clinical trials (European Organization for Research and Treatment of Cancer [EORTC] Quality of Life Questionnaire Core 30 [QLQ-C30] and breast cancer module [QLQ-BR23])...
July 31, 2017: JMIR Medical Informatics
https://www.readbyqxmd.com/read/28755097/provider-experiences-with-chronic-care-management-ccm-services-and-fees-a-qualitative-research-study
#9
Ann S O'Malley, Rumin Sarwar, Rosalind Keith, Patrick Balke, Sai Ma, Nancy McCall
BACKGROUND: Support for ongoing care management and coordination between office visits for patients with multiple chronic conditions has been inadequate. In January 2015, Medicare introduced the Chronic Care Management (CCM) payment policy, which reimburses providers for CCM activities for Medicare beneficiaries occurring outside of office visits. OBJECTIVE: To explore the experiences, facilitators, and challenges of practices providing CCM services, and their implications going forward...
July 28, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28754130/teasing-apart-the-tangled-web-of-influence-of-policy-dialogues-lessons-from-a-case-study-of-dialogues-about-healthcare-reform-options-for-canada
#10
Gillian Mulvale, Samantha A McRae, Sandra Milicic
BACKGROUND: The knowledge exchange literature suggests that policy dialogues are intended to enhance short-, medium- and long-term capacities of individuals, organizations and health systems to use evidence to inform policy-making. Key features of effective dialogues have been suggested, but the linkages between these features and the realization of improved capacities for evidence-informed policy-making among dialogue attendees and the subsequent influence on policy-making activities are not well understood...
July 28, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28749315/connecting-medical-records-an-evaluation-of-benefits-and-challenges-for-primary-care-practices
#11
Deborah Ruth Compeau, Amanda Terry
BACKGROUND: Implementation of systems to support health information sharing has lagged other areas of healthcare IT, yet offers a strong possibility for benefit.  Clinical acceptance is a key limiting factor in health IT adoption. OBJECTIVES: To assess the benefits and challenges experienced by clinicians using a custom-developed health information exchange system, and to show how perceptions of benefits and challenges influence perceptions of productivity and care-related outcomes...
June 30, 2017: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28747298/estimating-one-year-risk-of-incident-chronic-kidney-disease-retrospective-development-and-validation-study-using-electronic-medical-record-data-from-the-state-of-maine
#12
Shiying Hao, Tianyun Fu, Qian Wu, Bo Jin, Chunqing Zhu, Zhongkai Hu, Yanting Guo, Yan Zhang, Yunxian Yu, Terry Fouts, Phillip Ng, Devore S Culver, Shaun T Alfreds, Frank Stearns, Karl G Sylvester, Eric Widen, Doff B McElhinney, Xuefeng B Ling
BACKGROUND: Chronic kidney disease (CKD) is a major public health concern in the United States with high prevalence, growing incidence, and serious adverse outcomes. OBJECTIVE: We aimed to develop and validate a model to identify patients at risk of receiving a new diagnosis of CKD (incident CKD) during the next 1 year in a general population. METHODS: The study population consisted of patients who had visited any care facility in the Maine Health Information Exchange network any time between January 1, 2013, and December 31, 2015, and had no history of CKD diagnosis...
July 26, 2017: JMIR Medical Informatics
https://www.readbyqxmd.com/read/28745563/validity-of-routinely-collected-data-in-identifying-hip-fractures-at-a-major-tertiary-hospital-in-australia
#13
Lieu Thi Thuy Trinh, Helen Achat, Sze Ming Loh, Robert Pascoe, Hassan Assareh, Joanne Stubbs, Veth Guevarra
OBJECTIVES: To examine the validity of routinely collected data in identifying hip fractures (HFs) and to identify factors associated with incorrect coding. METHOD: In a prospective cohort study between January 2014 and June 2016, HFs were identified using physician diagnosis and diagnostic imaging and were recorded in a Registry. Records of HFs in the health information exchange (HIE) were identified using International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification/Australian Classification of Health Interventions/Australian Coding Standards codes...
January 1, 2017: HIM Journal
https://www.readbyqxmd.com/read/28744848/systems-and-precision-medicine-approaches-to-diabetes-heterogeneity-a-big-data-perspective
#14
Enrico Capobianco
Big Data, and in particular Electronic Health Records, provide the medical community with a great opportunity to analyze multiple pathological conditions at an unprecedented depth for many complex diseases, including diabetes. How can we infer on diabetes from large heterogeneous datasets? A possible solution is provided by invoking next-generation computational methods and data analytics tools within systems medicine approaches. By deciphering the multi-faceted complexity of biological systems, the potential of emerging diagnostic tools and therapeutic functions can be ultimately revealed...
December 2017: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/28741740/ultrafine-fine-and-black-carbon-particle-concentrations-in-california-child-care-facilities
#15
Fraser W Gaspar, Randy Maddalena, Jeffery Williams, Rosemary Castorina, Zhong-Min Wang, Kazukiyo Kumagai, Thomas E McKone, Asa Bradman
Although many U.S. children spend time in child care, little information exists on exposures to airborne particulate matter (PM) in this environment, even though PM may be associated with asthma and other respiratory illness, which is a key concern for young children. To address this data gap, we measured ultrafine particles (UFP), PM2.5 , PM10 , and black carbon in 40 California child care facilities and examined associations with potential determinants. We also tested a low-cost optical particle measuring device (Dylos monitor)...
July 25, 2017: Indoor Air
https://www.readbyqxmd.com/read/28737905/metabolism-of-t-2-toxin-in-farm-animals-and-human-in-vitro-and-in-chickens-in-vivo-using-ultra-high-performance-liquid-chromatography-quadrupole-time-of-flight-hybrid-mass-spectrometry-along-with-online-hydrogen-deuterium-exchange-technique
#16
Shupeng Yang, Marthe De Boevre, Huiyan Zhang, Karl De Ruyck, Feifei Sun, Jinzhen Zhang, Yue Jin, Yanshen Li, Zhanhui Wang, Suxia Zhang, Jinhui Zhou, Yi Li, Sarah De Saeger
After incubated with animals' and human liver microsomes, metabolites of phase I and II were investigated. A comparison was performed by ultrahigh performance liquid chromatography-quadrupole/time-of-flight coupled to mass spectrometry (UHPLC-Q/TOF). Consequently, a total of four phase I metabolites and three glucuronide binding metabolites of T-2 toxin were discovered. Although a significant metabolic difference was observed among six species, HT-2 toxin was the major product in all species. In addition, the in vivo metabolism of T-2 toxin after oral administration was also investigated in chickens, In total, 18 metabolites were detected, of which 13 were novel, to our knowledge, and reported for the first time...
July 24, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28734682/how-have-systematic-priority-setting-approaches-influenced-policy-making-a-synthesis-of-the-current-literature
#17
REVIEW
Lydia Kapiriri, Donya Razavi
BACKGROUND: There is a growing body of literature on systematic approaches to healthcare priority setting from various countries and different levels of decision making. This paper synthesizes the current literature in order to assess the extent to which program budgeting and marginal analysis (PBMA), burden of disease & cost-effectiveness analysis (BOD/CEA), multi-criteria decision analysis (MCDA), and accountability for reasonableness (A4R), are reported to have been institutionalized and influenced policy making and practice...
July 12, 2017: Health Policy
https://www.readbyqxmd.com/read/28733155/implementation-of-a-health-information-exchange-into-community-pharmacy-workflow
#18
Kenneth C Hohmeier, Christina A Spivey, Samantha Boldin, Tara B Moore, Marie Chisholm-Burns
OBJECTIVES: To explore the feasibility and report preliminary outcomes of the integration of a health information exchange (HIE) into community pharmacy workflow clinical service delivery. SETTING: Independent pharmacy in eastern Tennessee. PRACTICE DESCRIPTION: The pharmacy offers medication reconciliation services via HIE access, as well as other clinical pharmacy services. The average number of prescriptions filled weekly is 1900, and staffing included 3...
July 18, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28728473/parents-views-on-childhood-obesity-qualitative-analysis-of-discussion-board-postings
#19
Jessica Appleton, Cathrine Fowler, Nicola Brown
BACKGROUND: Childhood obesity is an increasing concern for parents and health professionals alike. Parents' perception of obesity as a current health issue for their children is important for the everyday parenting and health choices parents make. As parents are frequently going online to seek and exchange information about parenting and child health, asynchronous online discussion forums provide an opportunity to investigate their perceptions and concerns. Understanding parents' perceptions, beliefs and attitudes is important in any childhood obesity prevention and intervention...
July 21, 2017: Contemporary Nurse
https://www.readbyqxmd.com/read/28727441/adsorption-induced-changes-of-human-hemoglobin-on-ferric-pyrophosphate-nanoparticle-surface-probed-by-isotope-exchange-mass-spectrometry-an-implication-on-structure-function-correlation
#20
Bindu Y Srinivasu, Beena Bose, Gopa Mitra, Anura V Kurpad, Amit K Mandal
In general, proteins in the biological system interact with nanoparticles (NPs) via adsorption on the particle surface. Understanding the adsorption at the molecular level is crucial to explore NP-protein interactions. The increasing concerns about the risk to human health on NP exposure have been explored through the discovery of a handful protein biomarkers and biochemical analysis. However, detailed information on structural perturbation and associated functional changes of proteins on interaction with NPs is limited...
August 2, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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