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https://www.readbyqxmd.com/read/28209138/using-whole-genome-sequencing-to-investigate-transmission-in-a-multi-host-system-bovine-tuberculosis-in-new-zealand
#1
Joseph Crispell, Ruth N Zadoks, Simon R Harris, Brent Paterson, Desmond M Collins, Geoffrey W de-Lisle, Paul Livingstone, Mark A Neill, Roman Biek, Samantha J Lycett, Rowland R Kao, Marian Price-Carter
BACKGROUND: Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is an important livestock disease raising public health and economic concerns around the world. In New Zealand, a number of wildlife species are implicated in the spread and persistence of bTB in cattle populations, most notably the brushtail possum (Trichosurus vulpecula). Whole Genome Sequenced (WGS) M. bovis isolates sourced from infected cattle and wildlife across New Zealand were analysed. Bayesian phylogenetic analyses were conducted to estimate the substitution rate of the sampled population and investigate the role of wildlife...
February 16, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28207198/integrated-precision-medicine-the-role-of-electronic-health-records-in-delivering-personalized-treatment
#2
REVIEW
Amy Sitapati, Hyeoneui Kim, Barbara Berkovich, Rebecca Marmor, Siddharth Singh, Robert El-Kareh, Brian Clay, Lucila Ohno-Machado
Precision Medicine involves the delivery of a targeted, personalized treatment for a given patient. By harnessing the power of electronic health records (EHRs), we are increasingly able to practice precision medicine to improve patient outcomes. In this article, we introduce the scientific community at large to important building blocks for personalized treatment, such as terminology standards that are the foundation of the EHR and allow for exchange of health information across systems. We briefly review different types of clinical decision support (CDS) and present the current state of CDS, which is already improving the care patients receive with genetic profile-based tailored recommendations regarding diagnostic and treatment plans...
February 16, 2017: Wiley Interdisciplinary Reviews. Systems Biology and Medicine
https://www.readbyqxmd.com/read/28202595/image-based-modelling-of-skeletal-muscle-oxygenation
#3
REVIEW
B Zeller-Plumhoff, T Roose, G F Clough, P Schneider
The supply of oxygen in sufficient quantity is vital for the correct functioning of all organs in the human body, in particular for skeletal muscle during exercise. Disease is often associated with both an inhibition of the microvascular supply capability and is thought to relate to changes in the structure of blood vessel networks. Different methods exist to investigate the influence of the microvascular structure on tissue oxygenation, varying over a range of application areas, i.e. biological in vivo and in vitro experiments, imaging and mathematical modelling...
February 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28186059/information-exchange-between-providers-during-transitions-of-surgical-care-communication-documentation-and-sometimes-both
#4
Stacey Slager, Julie Beckstrom, Charlene Weir, Guilherme Del Fiol, Benjamin S Brooke
Poor communication of health information between healthcare providers is associated with over 80% of medical errors that occur during transitions of care [1]. We interviewed a diverse sample of primary care providers and surgical providers during their patient's transitions of care before and after surgery at a Veteran's Health Administration hospital and a large tertiary academic medical center to understand how providers communicate and exchange health information for medically complex older patient across different care settings...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28186039/integration-of-health-information-systems-using-hl7-a-case-study
#5
Jessica Wan-Yi Kuo, Alex Mu-Hsing Kuo
Interoperability is a prerequisite for health information systems (HIS) that will reduce waste of unnecessary costs, errors, delays, and futile repetition. Many previous studies had proposed different approaches in the attempt to solve interoperability challenges. In this paper, we report our experiences in using Health Level 7 (HL7) standard and adopting the Common Gateway Model for exchanging heath data. The benefits and challenges of using standards for data interoperability are also described.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28186016/collaborators-and-communication-channels-in-eight-patient-centered-medical-homes
#6
Dian A Chase, David A Dorr, Deborah J Cohen, Joan S Ash
BACKGROUND: The patient-centered medical home (PCMH) concept requires collaboration among clinicians both within the medical home clinic, and outside the clinic. As we redesign health information technology (HIT) to support transformation to the PCMH, we need to better understand these collaboration patterns. This study provides quantitative data describing these collaborations in order to facilitate the design of systems to allow for more efficient collaboration. APPROACH: Eighty-four clinicians in eight clinics identified their two most recent significant collaborators - one each within the clinic and in the medical neighborhood...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28183857/coexistent-sickle-cell-disease-has-no-impact-on-the-safety-or-outcome-of-lytic-therapy-in-acute-ischemic-stroke-findings-from-get-with-the-guidelines-stroke
#7
Robert J Adams, Margueritte Cox, Shelly D Ozark, Julie Kanter, Phillip J Schulte, Ying Xian, Gregg C Fonarow, Eric E Smith, Lee H Schwamm
BACKGROUND AND PURPOSE: The recommended treatment for ischemic stroke is tPA (tissue-type plasminogen activator). Although sickle cell disease (SCD) represents no known contraindication to tPA, National Heart Lung and Blood Institute of the National Institutes of Health recommended acute exchange transfusion for stroke in SCD, not tPA. Data on safety and outcomes of tPA in patients are needed to guide tPA use in SCD. METHODS: We matched patients from the American Heart Association and American Stroke Association Get With The Guidelines-Stroke registry with SCD to patients without SCD and compared usage, complications, and discharge outcomes after tPA...
February 9, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28173820/therapeutic-arthropods-and-other-largely-terrestrial-folk-medicinally-important-invertebrates-a-comparative-survey-and-review
#8
REVIEW
V Benno Meyer-Rochow
Traditional healing methods involving hundreds of insect and other invertebrate species are reviewed. Some of the uses are based on the tenet of "similia similibus" (let likes be cured by likes), but not all non-conventional health promoting practices should be dismissed as superstition or wishful thinking, for they have stood the test of time. Two questions are addressed: how can totally different organ systems in a human possibly benefit from extracts, potions, powders, secretions, ashes, etc. of a single species and how can different target organs, e...
February 7, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28173635/an-assessment-of-the-experiences-and-needs-of-adolescents-with-chronic-conditions-in-transitional-care-a-qualitative-study-to-develop-a-patient-education-programme
#9
Franziska Bomba, Carsten Herrmann-Garitz, Julia Schmidt, Silke Schmidt, Ute Thyen
The transition of adolescents with chronic conditions is a challenging task. This study aimed to explore the experiences and needs of adolescents with chronic conditions in the transition period and to apply these findings to the design of a generic patient education programme. Data were collected from a sample of 29 adolescents with chronic conditions from Northern Germany and Switzerland including a broad range of views due to variation in disease management and organisation of care both in paediatric and adult populations...
March 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28169176/breast-health-services-accuracy-of-benefit%C3%A2-coverage-information-in-the-individual-insurance-marketplace
#10
Mariam S Hamid, Giselle E Kolenic, Jessica Dozier, Vanessa K Dalton, Ruth C Carlos
PURPOSE: The aim of this study was to determine if breast health coverage information provided by customer service representatives employed by insurers offering plans in the 2015 federal and state health insurance marketplaces is consistent with Patient Protection and Affordable Care Act (ACA) and state-specific legislation. METHODS: One hundred fifty-eight unique customer service numbers were identified for insurers offering plans through the federal marketplace, augmented with four additional numbers representing the Connecticut state-run exchange...
January 27, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28167713/health-care-use-and-spending-patterns-vary-by-wage-level-in-employer-sponsored-plans
#11
Bruce W Sherman, Teresa B Gibson, Wendy D Lynch, Carol Addy
Employees face an increasing financial burden for health services as health care costs increase relative to earnings. Yet little is known about health care utilization patterns relative to employee wages. To better understand this association and the resulting implications, we examined patterns of health care use and spending by wage category during 2014 among 42,936 employees of four self-insured employers enrolled in a private health insurance exchange. When demographics and other characteristics were controlled for, employees in the lowest-wage group had half the usage of preventive care (19 percent versus 38 percent), nearly twice the hospital admission rate (31 individuals per 1,000 versus 17 per 1,000), more than four times the rate of avoidable admissions (4...
February 1, 2017: Health Affairs
https://www.readbyqxmd.com/read/28159008/unravelling-networks-in-local-public-health-policymaking-in-three-european-countries-a-systems-analysis
#12
Hilde P E M Spitters, Cathrine J Lau, Petru Sandu, Marcel Quanjel, Diana Dulf, Charlotte Glümer, Hans A M van Oers, Ien A M van de Goor
BACKGROUND: Facilitating and enhancing interaction between stakeholders involved in the policymaking process to stimulate collaboration and use of evidence, is important to foster the development of effective Health Enhancing Physical Activity (HEPA) policies. Performing an analysis of real-world policymaking processes will help reveal the complexity of a network of stakeholders. Therefore, the main objectives were to unravel the stakeholder network in the policy process by conducting three systems analyses, and to increase insight into the similarities and differences in the policy processes of these European country cases...
February 3, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28153027/a-call-for-collaboration-on-respectful-person-centered-health-care-in-family-planning-and-maternal-health
#13
Kelsey Holt, Jacquelyn M Caglia, Emily Peca, James M Sherry, Ana Langer
BACKGROUND: Striking tales of people judged, disrespected, or abused in reproductive, maternal, newborn, child, and adolescent health (RMNCAH) services are commonly exchanged among friends and families throughout the world while remaining sorely under-addressed in global health. Disrespect and abuse of individuals and providers in health services across the RMNCAH continuum must be stopped through collaborative, multi-tiered efforts. CALL FOR COLLABORATION: A new focus on health care quality in the Sustainable Development Goals offers an opportunity to seriously reexamine user experiences and their impact on health care utilization...
February 2, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28152865/patient-surveys-for-cancer-populations-initial-experiences-with-cancer-cahps
#14
Mark W Friedberg, Shelley Fuld Nasso, Lindsey M Roth, Aaron Smith-McLallen, Ellen L Stovall, Sarah Hudson Scholle
: 281 Background: Patient experiences are an important component of quality, but information on how well oncology providers meet the specific needs of patients with cancer is limited. This study reports on the patient experiences among patients undergoing drug therapy treatment for cancer in diverse outpatient settings. METHODS: We assessed patient experiences using a modified version of the CAHPS Survey for Cancer Caredeveloped by the American Institutes for Research...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152789/does-oncology-patient-reported-healthcare-experience-vary-by-site-of-care-soc
#15
Adrianne Waldman Casebeer, Sari Hopson, Joseph Dye, Zhuliang Tao, Andrew M Howe, Stephen Stemkowski, Jeffrey Patton, Art Small, Anthony Masaquel
: 71 Background: Patients with cancer are increasingly receiving chemotherapy infusions in a hospital outpatient (HO) as compared to the physician practice setting (PO). Previous research has focused on SOC differences in economic measures, such as healthcare costs, in commercially insured populations. This study investigates SOC differences in patients' reported healthcare experience for a mostly Medicare population. METHODS: A convenience sample of 2,604 Humana members with cancer of the breast, lung, colon/rectum or NHL/CLL and treated in 2014 received a survey by mail to capture patient reported healthcare experiences...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152226/medication-errors-in-home-care-a-qualitative-focus-group-study
#16
Astrid Berland, Signe Berit Bentsen
AIMS AND OBJECTIVES: To explore registered nurses' experiences of medication errors and patient safety in home care. BACKGROUND: The focus of care for older patients has shifted from institutional care toward a model of home care. Medication errors are common in this situation and can result in patient morbidity and mortality. DESIGN: An exploratory qualitative design with focus group interviews was used. METHODS: Four focus group interviews were conducted with 20 registered nurses in home care...
February 2, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28148228/health-economic-evaluation-of-human-papillomavirus-vaccines-in-women-from-venezuela-by-a-lifetime-markov-cohort-model
#17
Ariel Esteban Bardach, Osvaldo Ulises Garay, María Calderón, Andrés Pichón-Riviére, Federico Augustovski, Sebastián García Martí, Paula Cortiñas, Marino Gonzalez, Laura T Naranjo, Jorge Alberto Gomez, Joaquín Enzo Caporale
BACKGROUND: Cervical cancer (CC) and genital warts (GW) are a significant public health issue in Venezuela. Our objective was to assess the cost-effectiveness of the two available vaccines, bivalent and quadrivalent, against Human Papillomavirus (HPV) in Venezuelan girls in order to inform decision-makers. METHODS: A previously published Markov cohort model, informed by the best available evidence, was adapted to the Venezuelan context to evaluate the effects of vaccination on health and healthcare costs from the perspective of the healthcare payer in an 11-year-old girls cohort of 264,489...
February 2, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28144972/views-of-patient-healthcare-professionals-and-administrative-staff-on-flow-of-information-and-collaboration-in-a-regional-health-information-exchange-a-qualitative-study
#18
Tiina Mäenpää, Paula Asikainen, Tarja Suominen
BACKGROUND: Nowadays, patients can be more involved in developing healthcare services with their healthcare professionals. Patient-centred information is a key part of improving regional health information exchange (HIE), giving patients an active role in care management. AIM: The aim was to get a deeper understanding of the flow of information and collaboration in one hospital district area from the viewpoint of patients, healthcare professionals and administrative staff...
January 31, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/28144284/balancing-health-care-needs-in-a-changing-context-nursing-highlights-from-the-2016-european-oncology-nursing-society-congress-eons10-17-18-october-2016-dublin-ireland
#19
Danuta Lichosik, Rosario Caruso
European cancer nurses have to face many challenges as a result of the rapidly changing economic and political context in which balancing health care needs has become strategic for healthcare delivery. Currently, cancer nurses must overcome many obstacles arising from clinical, organisational, and educational issues. Within this scenario, the European Oncology Nursing Society (EONS) shaped its tenth congress programme to boost discussion and reflections, to share experiences and research, and to see how cancer nurses try to anticipate and embrace changes...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28138444/conscience-imperative-of-providing-information-and-knowledge-in-hepatology-the-portuguese-approach
#20
Guilherme Macedo, Marco Silva
The last 25 years have been a thrilling time for the Portuguese hepatologists. Our national meetings have been providing the forum for the exchange of scientific ideas and the presentation of clinical research in clinical Hepatology, a growing world of knowledge in medical care. Bridging the gaps between technology and clinical daily practice, the latest development and the almost humble bedside care, has been a challenge for the increasing numbers of doctors devoted to the diagnostic and treatment of liver disease...
January 16, 2017: World Journal of Clinical Cases
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