A Emery, S Moore, J Crowe, J Murray, O Peacock, D Thompson, F Betts, S Rapps, L Ross, D Rothschild-Rodriguez, A Arana Echarri, R Davies, R Lewis, D X Augustine, A Whiteway, Z Afzal, Jlj Heaney, M T Drayson, J E Turner, J P Campbell
BACKGROUND: High levels of physical activity are associated with reduced risk of the blood cancer multiple myeloma (MM). MM is preceded by the asymptomatic stages of monoclonal gammopathy of undetermined significance (MGUS) and smouldering multiple myeloma (SMM) which are clinically managed by watchful waiting. A case study (N = 1) of a former elite athlete aged 44 years previously indicated that a multi-modal exercise programme reversed SMM disease activity. To build from this prior case study, the present pilot study firstly examined if short-term exercise training was feasible and safe for a group of MGUS and SMM patients, and secondly investigated the effects on MGUS/SMM disease activity...
February 5, 2024: BMC Cancer