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https://www.readbyqxmd.com/read/28334520/new-approach-for-vertical-bone-regeneration-using-in-situ-gelling-and-sustained-bmp-2-releasing-poly-phosphazene-hydrogel-system-on-peri-implant-site-with-critical-defect-in-a-canine-model
#1
Bo-Bae Seo, Hae-Im Chang, Hyuck Choi, Jeong-Tae Koh, Kwi-Dug Yun, Jae-Yeol Lee, Soo-Chang Song
An injectable hydrogel system with sustained bone morphogenetic protein 2 (BMP-2) release ability was developed for vertical bone regeneration at peri-implant sites and enhanced osseointegration of dental implants. In three young male beagle dogs, a pair of defects was created on both sides of the mandibular bone. Next, two implants were transplanted into each defect. In situ gelling polymer solutions with or without BMP-2 were applied to cover the implants and mandibular defects. The effects of the in situ gelling and sustained BMP-2 releasing (IGSR) hydrogel system on peri-implant bone regeneration were evaluated by radiologic examination, micro-computed tomography, and histomorphometric analysis...
March 23, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28334450/short-term-effects-of-arthrotomy-with-and-without-infrapatellar-fat-pad-resection-on-the-normal-canine-stifle
#2
Yukihiro Fujita, Tetsuya Nakajo, Makoto Muto
OBJECTIVE: To investigate the short-term effects of infrapatellar fat pad (IFP) resection in normal dogs. STUDY DESIGN: Experimental in vivo study. ANIMALS: Five normal adult female beagle dogs. METHODS: The IFP was resected via arthrotomy in the left stifle joint (experimental side) while the right stifle underwent arthrotomy alone (sham side). An orthopedic examination was performed every week for 4 weeks and synovial fluid was analyzed before and 4 weeks after the procedure...
March 23, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28334448/carotid-artery-bursting-pressure-and-seal-time-after-multiple-uses-of-a-vessel-sealing-device
#3
Jocelin S Blake, Brian J Trumpatori, Kyle G Mathews, Emily H Griffith
OBJECTIVE: To determine any loss of function of a single-use bipolar vessel sealing device after repeated sterilization and use on canine carotid arteries. STUDY DESIGN: Ex vivo; randomized block design (dog). SAMPLE POPULATION: Carotid artery segments (n = 90) from 15 canine cadavers. METHODS: Six 10-mm LigaSure Atlas 20 cm devices (Covidien Inc, Minneapolis, Minnesota) were used to seal canine carotid artery segments in one cadaver, then resterilized using ethylene oxide and reused in a second cadaver, and so on, for a total of 15 uses/15 cadavers per LigaSure...
March 23, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28333306/protein-aggregation-in-ehrlichia-chaffeensis-during-infection-of-mammalian-cells
#4
Dorota Kuczynska-Wisnik, Chuanmin Cheng, Roman R Ganta, Michal Zolkiewski
Ehrlichia chaffeensis is an obligatory intracellular pathogen transmitted through infected ticks to humans and other vertebrates. We investigated the extent of protein aggregation in E. chaffeensis during infection of canine macrophage cell line, DH82. We discovered that the size of the aggregated fraction of E. chaffeensis proteins increased during the first 48 h post infection. We also incubated the infected cells with guanidinium chloride (GuHCl), a known inhibitor of the protein-disaggregating molecular chaperone ClpB...
March 15, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28332211/a-multi-channel-block-matching-denoising-algorithm-for-spectral-photon-counting-ct-images
#5
Adam P Harrison, Ziyue Xu, David A Bluemke, Amir Pourmorteza, Daniel J Mollura
PURPOSE: We present a denoising algorithm designed for a whole-body prototype photon-counting computed tomography (PCCT) scanner with up to 4 energy thresholds and associated energy-binned images. METHODS: Spectral PCCT images can exhibit low signal to noise ratios (SNRs) due to the limited photon counts in each simultaneously-acquired energy bin. To help address this, our denoising method exploits the correlation and exact alignment between energy bins, adapting the highly-effective block-matching 3D (BM3D) denoising algorithm for PCCT...
March 23, 2017: Medical Physics
https://www.readbyqxmd.com/read/28331832/glucosamine-and-chondroitin-use-in-canines-for-osteoarthritis-a-review
#6
REVIEW
Angel Bhathal, Meredith Spryszak, Christopher Louizos, Grace Frankel
Osteoarthritis is a slowly progressive and debilitating disease that affects canines of all breeds. Pain and decreased mobility resulting from osteoarthritis often have a negative impact on the affected canine's quality of life, level of comfort, daily functioning, activity, behaviour, and client-pet companionship. Despite limited and conflicting evidence, the natural products glucosamine hydrochloride (HCl) and chondroitin sulfate are commonly recommended by veterinarians for treating osteoarthritis in dogs...
2017: Open veterinary journal
https://www.readbyqxmd.com/read/28331282/reduced-phosphocreb-in-m%C3%A3-ller-glia-during-retinal-degeneration-in-rd10-mice
#7
Enheng Dong, Amelia Bachleda, Yubin Xiong, Shoji Osawa, Ellen R Weiss
PURPOSE: The mechanisms that trigger retinal degeneration are not well understood, despite the availability of several animal models with different mutations. In the present report, the rd10 mouse, a model for retinitis pigmentosa (RP) that contains a mutation in the gene for PDE6β (Pde6b), is used to evaluate gliosis, as a marker for retinal stress, and cyclic AMP response element binding protein (CREB) phosphorylation, which may be important early in retinal degeneration. METHODS: Wild-type C57Bl6J and rd10 mice raised under cyclic light were examined for changes in gliosis and CREB phosphorylation for approximately 3 weeks beginning at P14 to P17 using immunocytochemistry...
2017: Molecular Vision
https://www.readbyqxmd.com/read/28330574/bi-maxillary-dentigerous-cyst-in-a-non-syndromic-child%C3%A2-%C3%A2-review-of-literature-with-a-case-presentation
#8
A Dhupar, S Yadav, V Dhupar, H C Mittal, S Malik, P Rana
Dentigerous cysts are the most common developmental odontogenic cysts of the jaw, which usually occur in the second and third decade of life. It is most frequently associated with impacted mandibular third molar teeth and impacted canines. Bilateral/multiple dentigerous cysts are rare and typically associated with developmental syndromes. Non-syndromic dentigerous cyst occurring bilaterally or involving both arches at the same time is very rare. Here, we discuss the review of literature with a case of unusual occurrence of non-syndromic bi-maxillary dentigerous cysts in a child...
February 2017: J Stomatol Oral Maxillofac Surg
https://www.readbyqxmd.com/read/28327849/-effect-of-free-roaming-dogs-culling-on-the-control-of-canine-rabies
#9
Ricardo Castillo-Neyra, Michael Z Levy, Cesar Náquira
In the Peruvian city of Arequipa, rabid dogs have been detected since March 2015, signaling the reintroduction of the rabies virus (RV) in this previously officially-declared rabies free zone. High dog density is considered one of the causes for the continuous transmission of the RV in the outbreak in the city of Arequipa, which seemingly lends support to the culling of dogs as a public health measure. However, the effectiveness of culling free-roaming dogs to control urban rabies has not been evaluated. Objective to determine the effectiveness of free-roaming dog culling as a control measure of urban rabies...
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28327803/serodiagnosis-of-visceral-and-cutaneous-leishmaniasis-in-human-and-canine-populations-living-in-indigenous-reserves-in-the-brazilian-amazon-region
#10
Julia Teresa Ribeiro de Lima, Solange Maria Gennari, Herbert Sousa Soares, Antonio Humberto Hamad Minervino, Antonio Francisco Malheiros, Fernando Silveira Marques, Márcia Dalastra Laurenti, Rosangela Zacarias Machado, Arlei Marcili, Marcelo Bahia Labruna, Rodrigo Martins Soares
INTRODUCTION: Leishmaniasis is endemic to the Northern, Northeastern, Central-Western, and Southeastern regions of Brazil. We aimed to assess the epidemiological situation of leishmaniasis in humans and dogs in indigenous villages located in the States of Mato Grosso and Tocantins using a serological survey conducted in May 2011. METHODS: Serum samples were collected from 470 humans and 327 dogs living in villages of the Urubu Branco and Tapirapé Karajá indigenous reserves...
January 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28327794/seasonality-of-sand-flies-diptera-psychodidae-and-leishmania-dna-detection-in-vector-species-in-an-area-with-endemic-visceral-leishmaniasis
#11
Lara Saraiva, Camila Gonçalves Leite, Ana Cristina Vianna Mariano da Rocha Lima, Luiz Otávio Alves de Carvalho, Agnes Antônia Sampaio Pereira, Jerônimo Marteleto Nunes Rugani, Felipe Dutra Rego, Célia Maria Ferreira Gontijo, José Dilermando Andrade
BACKGROUND: Leishmaniases are a serious health problem in southeast Brazil, including the city of Belo Horizonte (BH), Minas Gerais state (MG), where there are high rates of incidence and mortality due to visceral leishmaniases. BH is divided into nine sanitary districts (SD) of which one, the Venda Nova SD, was selected for this study because it has high rates of positivity for canine leishmaniasis and high incidence of human leishmaniasis. OBJECTIVES: This study aimed to survey the sand fly fauna in Venda Nova SD from August 2011 to July 2013 and perform a descriptive analysis of the vector population...
April 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28327525/prevalence-of-malocclusion-in-3-to-5-year-old-children-in-shanghai-china
#12
Xinhua Zhou, Ying Zhang, Yan Wang, Hao Zhang, Li Chen, Yuehua Liu
The aim of the present study was to obtain the prevalence of malocclusions in preschool children in Shanghai, China. A cross-sectional survey was conducted among 2335 children aged 3-5 years from kindergartens. Several occlusal parameters were clinically assessed, including second deciduous molar terminal plane, canine relationship, degree of overjet and overbite, anterior and posterior crossbite, and the presence or absence of physiologic spaces and crowding. All parents of subjects were asked to fill in the oral health knowledge questionnaires...
March 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28327262/clinical-performance-of-pedo-jacket-crowns-in-maxillary-anterior-primary-teeth
#13
Aimee Castro, Sherine B Y Badr, Wafa El-Badrawy, Gajanan Kulkarni
PURPOSES: To assess the clinical performance of Pedo Jacket crowns for restoration of carious primary anterior teeth. METHODS: A total of 129 carious primary incisors and canines of 48 children younger than 71 months of age- were restored with Pedo Jacket crowns and resin-modified glass ionomer cementation. They were assessed for: ease of use; presence of recurrent decay; wear; partial or complete loss of the crown; color stability; gingival health; and overall clinical success over a 12-month follow-up...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28327134/the-effect-of-intra-articular-botulinum-toxin-a-on-substance-p-prostaglandin-e2-and-tumor-necrosis-factor-alpha-in-the-canine-osteoarthritic-joint
#14
Helka M Heikkilä, Anna K Hielm-Björkman, John F Innes, Outi M Laitinen-Vapaavuori
BACKGROUND: Recently, intra-articular botulinum toxin A (IA BoNT A) has been shown to reduce joint pain in osteoarthritic dogs. Similar results have been reported in human patients with arthritis. However, the mechanism of the antinociceptive action of IA BoNT A is currently not known. The aim of this study was to explore this mechanism of action by investigating the effect of IA BoNT A on synovial fluid (SF) and serum substance P (SP), prostaglandin E2 (PGE2), and tumor necrosis factor alpha (TNF-α) in osteoarthritic dogs...
March 21, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28327073/the-influence-of-axial-grooves-on-dislodgment-resistance-of-prosthetic-metal-crowns-in-canine-teeth-of-dogs
#15
Stephanie Goldschmidt, Caitlyn J Collins, Scott Hetzel, Heidi-Lynn Ploeg, Jason W Soukup
The reported failure rate for full veneer crowns of canine teeth of dogs is suboptimal, particularly in teeth with naturally poor retentive features, such as those with low height/diameter (H/D) ratios or high convergence angles (CAs). The objective of the present study was to evaluate the application of axial grooves in an effort to develop a crown preparation design that enhances the retention of full veneer crowns in dogs. Crown dislodgment testing was performed on cast alloy dies of canine teeth with unfavorable retention features (low H/D and high CA) prepared with (n = 14) and without axial grooves (n = 15) to evaluate the force required to dislodge a cemented full veneer crown...
September 2016: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28327068/management-of-mesioverted-maxillary-canine-teeth-and-linguoverted-mandibular-canine-teeth
#16
Mary Krakowski Volker, Ira R Luskin
Mesioverted maxillary canine teeth in combination with linguoverted mandibular canine teeth are a common ramification of persistent deciduous maxillary and mandibular canine teeth. Without the physical presence of the mandibular canine teeth, the maxillary third incisor and canine teeth diastemata are frequently narrowed. The creation of normal occlusion requires treatment of all 4 canine teeth; the mandibular canine teeth must be tipped labially and the maxillary canine teeth must be tipped and/or partially translated distally...
September 2016: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28327065/the-influence-of-axial-grooves-on-dislodgment-resistance-of-prosthetic-metal-crowns-in-maxillary-fourth-premolar-teeth-of-dogs
#17
Stephanie Goldschmidt, Caitlyn J Collins, Scott Hetzel, Heidi-Lynn Ploeg, Jason W Soukup
The reported failure rate for full veneer crowns in dogs is suboptimal, particularly in teeth with naturally poor retentive features such as the maxillary fourth premolar tooth of dogs. Although the data regarding crown retention on the maxillary fourth premolar in dogs are limited, there are data that suggest the crown failure rate could be similar to that of the canine tooth. Thus, methods to improve retentive features of the preparation design should be pursued. The objective of the present study is to quantify the influence of axial grooves on the dislodgment resistance of full veneer metal crowns in dogs...
September 2016: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28326982/maxillary-canine-tooth-extraction-for-class-2-malocclusion-in-a-dog
#18
Molly Angel
Malocclusion in dogs is commonly diagnosed in puppies when the primary dentition is present. Interceptive orthodontic treatment may be elected to temporarily resolve painful contact points with the primary dentition. However, the adult dentition must be monitored closely and treated to achieve a lifelong, pain-free occlusion. This case report illustrates interceptive orthodontic treatment of deciduous and permanent dentition to treat a class 2 malocclusion in a dog. Extraction of the permanent maxillary canine tooth was elected to resolve abnormal contact from the mandibular canine in a single anesthetic episode...
June 2016: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28326663/a-morphometric-study-of-the-canine-skull-and-periorbita-and-its-implications-for-regional-ocular-anesthesia
#19
Paulo Roberto Klaumann, Juan Carlos Duque Moreno, Fabiano Montiani-Ferreira
OBJECTIVE: A hypothetical relationship between canine cranial length and the length of the periorbita could be used for intraconal anesthetic volume estimation. STUDY SUBJECTS: Forty-one canine cadaver heads and one macerated dog skull. PROCEDURES: Inion and nasion points were recognized in the macerated skull and used as landmarks for cranial length measure. Thirty cadavers classified as dolichocephalic, mesaticephalic and brachycephalic were distributed in three study groups...
March 22, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28326102/impacted-maxillary-canine-prevalence-and-its-association-with-other-dental-anomalies-in-a-mexican-population
#20
José Rubén Herrera-Atoche, María Del Rosario Agüayo-de-Pau, Mauricio Escoffié-Ramírez, Fernando Javier Aguilar-Ayala, Bertha Arelly Carrillo-Ávila, Marina Eduviges Rejón-Peraza
Objective. We quantified the prevalence of impacted maxillary canines (IMC) and their association with other dental anomalies (DAs). Materials and Methods. A retrospective study was done with 860 patients 12 to 39 years of age. The prevalence of IMC was calculated and compared by sex. The sample was divided into a control group and an impaction group, and the prevalence was calculated in both for a series of anomalies: agenesis, supernumerary teeth, shape anomalies of the upper laterals (microdontia, peg and barrel shape, and talon cusp), fusion, gemination, other impacted teeth, transposition, and amelogenesis imperfecta...
2017: International Journal of Dentistry
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