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https://www.readbyqxmd.com/read/28527056/pathogenesis-of-chronic-cluster-headache-and-bouts-role-of-tryptamine-arginine-metabolism-and-%C3%AE-1-agonists
#1
G D'Andrea, G Bussone, P Di Fiore, F Perini, A Gucciardi, A Bolner, M Aguggia, G Saracco, E Galloni, G Giordano, A Leon
The aim of this study was to explore the possible role of tryptamine in the pathogenesis of chronic cluster headache along with that of adrenaline and noradrenaline (α-agonists) together with arginine metabolism in the origin of cluster bouts. Plasma levels of tyramine, tryptamine, serotonin, 5-hydroxyindolacetic acid, noradrenalin, adrenalin and the markers of arginine metabolism such as arginine, homoarginine, citrulline, ADMA and NMMA, were measured in 23 chronic cluster headache patients (10 chronic cluster ab initio and 13 transformed from episodic cluster) and 28 control subjects...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28522678/cigarette-smoking-associated-alterations-in-serotonin-adrenalin-signaling-pathways-of-platelets
#2
Curtis Lee Lowery, Clay Elliott, Anthonya Cooper, Coedy Hadden, Roberto N Sonon, Parastoo Azadi, D Keith Williams, James D Marsh, Donna S Woulfe, Fusun Kilic
BACKGROUND: Cigarette smoking plays a major role in cardiovascular diseases. The acute effects of cigarette smoking produce central nervous system-mediated activation of the sympathetic nervous system. The overactive sympathetic nervous system stimulates the secretion of serotonin (5-HT) and catecholamine into blood at supraphysiological levels. The correlation between these pathological conditions induced by smoking and the increased risk of thrombosis has not been thoroughly investigated...
May 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28512033/bifidobacterium-cect-7765-modulates-early-stress-induced-immune-neuroendocrine-and-behavioral-alterations-in-mice
#3
A Moya-Pérez, A Perez-Villalba, A Benítez-Páez, I Campillo, Y Sanz
Emerging evidence suggests that there is a window of opportunity within the early developmental period, when microbiota-based interventions could play a major role in modulating the gut-brain axis and, thereby, in preventing mood disorders. This study aims at evaluating the effects and mode of action of Bifidobacterium pseudocatenulatum CECT 7765 in a murine model of chronic stress induced by maternal separation (MS). C57Bl/6J male breast-fed pups were divided into four groups, which were subjected or not to MS and supplemented with placebo or B...
May 13, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28511742/predictors-for-routine-admission-to-paediatric-intensive-care-for-post-supraglottoplasty-laryngomalacia-patients
#4
S Chan, G Siou, A Welch, S Powell
OBJECTIVES: Supraglottoplasty for the treatment of laryngomalacia has little current evidence regarding post-operative care. Our study aimed to: (1) retrospectively assess what proportion of patients required paediatric intensive care unit level of care; (2) identify pre-operative predictive factors common to these cases; and (3) report patient outcomes at six weeks' follow up. METHODS: A 10-year retrospective case series analysis was conducted of all patients diagnosed with laryngomalacia and subsequently treated with supraglottoplasty...
May 17, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28510350/real-life-comparison-of-three-general-paediatric-wards-showed-similar-outcomes-for-children-with-bronchiolitis-despite-different-treatment-regimens
#5
Einat Shmueli, Tal Berger, Yonatan A Herman, Gabriel Chodick, Eran Rom, Efraim Bilavsky, Liat Ashkenazi-Hoffnung, Shai Ashkenazi, Jacob Amir, Dario Prais
AIM: This study evaluated the effectiveness of three different treatments for bronchiolitis in a tertiary pediatric facility. METHODS: Patients with bronchiolitis who were younger than two years of age and were randomly allocated to three general wards at Schneider Children's Medical Center, Israel, after admission were included. Different treatment protocols in the wards were retrospectively compared. RESULTS: The study comprised 286 children...
May 16, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28503322/changes-in-oxidized-ldl-during-a-half-marathon-in-athletes-with-spinal-cord-injuries
#6
Toshihito Mitsui, Tomoyuki Ito, Yusuke Sasaki, Takashi Kawasaki, Takeshi Nakamura, Yukihide Nishimura, Tatsuru Ibusuki, Yukiharu Higuchi, Sayoko Hosoe, Fumiaki Ito, Fumihiro Tajima
INTRODUCTION: We reported previously that exercise significantly increases plasma adrenaline and oxidized low-density lipoprotein (oxLDL) in healthy subjects but not in persons with spinal cord injury (SCI). Since oxLDL and adrenaline levels are associated with oxidant/antioxidant balance, and exercise training elicits production of reactive oxygen species, we elucidated the effects of exercise on adrenaline, oxidant/antioxidant balance and oxLDL in individuals with SCI. CASE PRESENTATION: Eight subjects with cervical spinal cord injury (CSCI) and nine subjects with lower lesion of SCI (lower SCI (LSCI)) participated in a wheelchair half marathon race, and blood samples were collected before (pre), immediately after (post) and 1 h after the race (post 1 h)...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28498273/effects-of-preoperative-psychological-interventions-on-catecholamineand-cortisol-levels-after-surgery-in-coronary-artery-bypass-graft-patients-the-randomized-controlled-psy-heart-trial
#7
Stefan Salzmann, Frank Euteneuer, Johannes A C Laferton, Charlotte J Auer, Meike C Shedden-Mora, Manfred Schedlowski, Rainer Moosdorf, Winfried Rief
OBJECTIVE: To examine whether preoperative psychological interventions targeting patients' expectations are capable of influencing the biological stress response after coronary artery bypass graft (CABG) surgery and could thus improve recovery after heart surgery. METHODS: Randomized controlled trial with assessments 10 days before surgery, post-psychological intervention (day of hospital admission, but before surgery), postoperative (6-8 days later) and at follow-up (6 months after surgery)...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28488828/effects-of-active-recovery-during-interval-training-on-plasma-catecholamines-and-insulin
#8
Harutiun M Nalbandian, Zsolt Radak, Masaki Takeda
BACKGROUND: Active recovery has been used as a method to accelerate the recovery during intense exercise. It also has been shown to improve performance in subsequent exercises, but little is known about its acute effects on the hormonal and metabolic profile. The aim of this research was to study the effects of active recovery on plasma catecholamines and plasma insulin during a high-intensity interval exercise. METHODS: 7 subjects performed two high-intensity interval training protocols which consisted of three 30 s high-intensity bouts (constant intensity), separated by a recovery of 4 minutes...
May 9, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28487840/medical-certification-reduces-the-number-of-children-requiring-allergen-elimination-diets-for-school-lunches
#9
Seigo Korematsu, Kenji Toyokuni, Yousuke Handa, Chika Gotoh, Rieko Wasada, Rie Kato, Nanae Kawano, Mayo Ikeuchi, Tomoko Okamoto, Maki Kiriya, Mizuho Takahashi, Tomoyuki Takano, Atsuhiko Haigo
BACKGROUND: Following the increase in the number of children with food allergies, support systems are now required for school lunches, but a large-scale factual investigation has not been carried out. OBJECTIVE: We evaluated the features of elimination diet due to food allergy and the support system in kindergartens and schools. METHODS: A prefecture-based questionnaire survey regarding measures for food allergies in school lunches of all kindergartens, public elementary schools, and public junior high schools (631 facilities) was conducted in Oita Prefecture, Japan...
April 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28486885/the-early-history-of-adrenaline
#10
C M Ball, P J Featherstone
No abstract text is available yet for this article.
May 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28482886/adrenaline-overdose-in-pediatric-anaphylaxis-a-case-report
#11
Pui Yi Lily Liew, John Andrew Craven
BACKGROUND: Adrenaline is the standard treatment for anaphylaxis but appropriate administration remains challenging, and iatrogenic overdose is easily overlooked. Despite the established importance of pediatric blood pressure measurement, its use remains inconsistent in clinical practice. CASE PRESENTATION: We report a case of adrenaline overdose in a 9-year-old white boy with anaphylaxis, where signs of adrenaline overdose were indistinguishable from progressive shock until blood pressure measurement was taken...
May 8, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28481181/a-diabetic-pregnancy-alters-the-expression-of-stress-related-receptors-in-gastrulating-rabbit-blastocyst-and-in-the-reproductive-tract
#12
Tom Seeling, Štefan Čikoš, Katarzyna J Grybel, Žofia Janštová, S Mareike Pendzialek, Maria Schindler, Alexandra Špirková, Anne Navarrete Santos
The incidence of diabetes mellitus for young people rises since years. A preconceptional diabetes mellitus leads to subfertility. Most of the causes for a diabetic subfertility are still unknown. Stress can significantly deteriorate glycemic control in diabetes. Several mechanisms by which "stress hormones", like adrenaline and cortisol or corticosterone, can contribute to the regulation of glucose homeostasis have been identified. Using reverse transcription-polymerase chain reaction (RT-PCR) and quantitative real-time RT-PCR, we examined the expression of adrenergic receptors and the glucocorticoid receptor transcripts in the female rabbit reproductive tract and in gastrulating blastocysts developed in normoinsulinemic mothers and in mothers with experimentally induced diabetes mellitus type 1...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28480848/acute-viral-bronchiolitis-in-infants-review
#13
I Chkhaidze, D Zirakishvili
Bronchiolitis is a common condition in children less than 2 years of age and is a leading cause of infant hospitalization. Acute bronchiolitis is characterized by acute wheezing in infants or children and is associated with signs or symptoms of respiratory infection; the most common etiologic agent is respiratory syncytial virus. There is a lack of consensus regarding the clinical definition of acute viral bronchiolitis in children and hence the management varies across the globe. Usually it does not require investigation, treatment is merely supportive and a conservative approach seems adequate in the majority of children, especially for the youngest ones...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480615/food-allergy-and-attitudes-to-close-interpersonal-relationships-an-exploratory-study-on-attachment
#14
Laura Polloni, Sami Schiff, Emilia Ferruzza, Francesca Lazzarotto, Roberta Bonaguro, Alice Toniolo, Nicolò Celegato, Muraro Antonella
BACKGROUND: Food allergy is a common immunological disease that includes potentially fatal reactions. It impacts considerably on patients' social life including close interpersonal relationships. Attachment theory provides a theoretical framework to evaluate the quality of close interpersonal relationships in chronic disorders. Attachment insecurity, mainly characterized by attachment avoidance, has been found in a variety of health conditions, but still needs to be investigated in food allergy...
May 8, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28472693/salivary-alpha-amylase-and-noradrenaline-responses-to-corticotropin-releasing-hormone-administration-in-humans
#15
Liubov Petrakova, Karoline Boy, Lisa Mittmann, Lars Möller, Harald Engler, Manfred Schedlowski
Salivary alpha-amylase (sAA) is a digestive enzyme mainly responsible for the hydrolysis of starch and glycogen in the oral cavity. Since the secretion of sAA is largely under the control of the sympathetic nervous system, sAA activity is also considered to be a non-invasive marker of sympathetic activation. However, the direct association between sAA activity and other sympathetic parameters remains questionable. Therefore, we employed the corticotropin-releasing hormone (CRH) stimulation test to pharmacologically activate the sympathetic nervous system and to analyze plasma noradrenaline response together with sAA activity...
May 1, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28468607/does-local-infiltration-analgesia-reduce-peri-operative-inflammation-following-total-hip-arthroplasty-a-randomized-double-blind-study
#16
J Kuchálik, A Magnuson, E Tina, A Gupta
BACKGROUND: Postoperative inflammation following total hip arthroplasty (THA) can lead to delayed mobilization and return of hip function. Our primary aim was to assess whether local infiltration analgesia (LIA) during surgery can prevent postoperative inflammation. METHODS: This is a sub-analysis of data from a broader double-blind study where 56 patients received spinal anaesthesia for THA. Additionally, Group FNB (Femoral Nerve Block) received an ultrasound-guided femoral nerve block using 30 mL of ropivacaine 7...
May 3, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28466714/adrenaline-pen-prescriptions-for-children-have-risen-significantly
#17
(no author information available yet)
Researchers have found that prescriptions of adrenaline autoinjectors, commonly called adrenaline pens, for children in the UK with allergies have increased markedly.
May 3, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28449948/sunitinib-specifically-augments-glucose-induced-insulin-secretion
#18
Stefan Z Lutz, Axel Ullrich, Hans-Ulrich Häring, Susanne Ullrich, Felicia Gerst
The tyrosine kinase inhibitor sunitinib is used for the treatment of numerous cancers in humans. In diabetic patients, sunitinib lowers blood glucose levels and improves glycaemic control. This study aims to analyse whether sunitinib has specific and direct effects on insulin secreting β-cells. Regulation of insulin secretion, of cellular cAMP levels and activation of signalling pathways were examined upon exposure of rat insulinoma INS-1E cells to sunitinib under specific stimulatory and inhibitory conditions...
April 24, 2017: Cellular Signalling
https://www.readbyqxmd.com/read/28447331/understanding-action-and-adventure-sports-participation-an-ecological-dynamics-perspective
#19
Tuomas Immonen, Eric Brymer, Dominic Orth, Keith Davids, Francesco Feletti, Jarmo Liukkonen, Timo Jaakkola
Previous research has considered action and adventure sports using a variety of associated terms and definitions which has led to confusing discourse and contradictory research findings. Traditional narratives have typically considered participation exclusively as the pastime of young people with abnormal characteristics or personalities having unhealthy and pathological tendencies to take risks because of the need for thrill, excitement or an adrenaline 'rush'. Conversely, recent research has linked even the most extreme forms of action and adventure sports to positive physical and psychological health and well-being outcomes...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28439159/a-randomized-controlled-study-comparing-efficacy-of-classical-and-gow-gates-technique-for-providing-anesthesia-during-surgical-removal-of-impacted-mandibular-third-molar-a-split-mouth-design
#20
Nanjappa Madan, Kateel Shashidhara Kamath, A L Gopinath, A Yashvanth, Nagaraj Vaibhav, G Praveen
INTRODUCTION: Reliable profound mandibular block anesthesia is questionable when depositing the anesthetic solution at the lingula. The Gow-Gates technique is an useful alternative to the classical inferior alveolar nerve block and the incidence of unsuccessful anesthesia may be as high as classical technique. The aim of this study is to compare the clinical efficacy, degree of patient acceptability, advantages, disadvantages and limitations of the classical and Gow-Gates techniques for providing anesthesia in patients undergoing bilateral symmetrical surgical removal of impacted mandibular third molar under local anesthesia...
June 2017: Journal of Maxillofacial and Oral Surgery
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