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chronic sinusitis and treatment

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https://www.readbyqxmd.com/read/29154250/functional-endoscopic-sinus-surgery-fess-in-unilateral-sinus-disease
#1
Daniela Mielcarek-Kuchta, Karolina Simon, Dawid Kondratowicz, Zofia Łukomska, Aleksandra Rybak-Korytowska
BACKGROUND: Unilateral sinus disease (USD) occurs in 23 % of all cases. It is believed that it is mainly associated with cancer development. Retrospective data from large rhinological centers show that the most common USD is chronic rhinosinusitis (CRS), followed by mycosis, inverted papilloma and finally cancer, but only in a small percent of cases. THE AIM OF THE STUDY: The analysis of USD in the group of patients who underwent FESS at the secondary referral center...
October 30, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29151786/concurrent-middle-and-inferior-meatus-antrostomy-for-the-treatment-of-maxillary-mucoceles
#2
Silviu Albu, Alina Gabriela Dutu
Background and aims: This study describes the technique of simultaneous middle and inferior antrostomy and outlines its usefulness in the management of maxillary mucoceles. Methods: This is a retrospective review of 12 consecutive patients with isolated maxillary mucocele operated on by means of middle and inferior antrostomy technique. We describe the clinical picture, details of the surgical technique and outcomes. Results: There were 7 males and 5 females with ages ranging from 20 years to 65 years (mean 42 years)...
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29133225/longitudinal-evaluation-of-chronic-rhinosinusitis-symptoms-in-a-population-based-sample
#3
Agnes S Sundaresan, Annemarie G Hirsch, Amanda J Young, Jonathan Pollak, Bruce K Tan, Robert P Schleimer, Robert C Kern, Thomas L Kennedy, J Scott Greene, Walter F Stewart, Karen Bandeen-Roche, Brian S Schwartz
BACKGROUND: Chronic rhinosinusitis (CRS) is a prevalent and disabling condition of the nose and sinuses. The natural history of CRS symptoms in a general population sample has not been previously studied. OBJECTIVE: In a general population-based sample from Pennsylvania, we used 2 questionnaires mailed 6 months apart to estimate the prevalence of, and identify predictors for, stability or change in symptoms over time. METHODS: We mailed the baseline and 6-month follow-up questionnaires to 23,700 primary care patients and 7,801 baseline responders, respectively...
November 10, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29119077/osteomyelitis-of-the-pelvic-bones-a-multidisciplinary-approach-to-treatment
#4
Maria Dudareva, Jamie Ferguson, Nicholas Riley, David Stubbs, Bridget Atkins, Martin McNally
Background and Purpose: A case series review of chronic pelvic osteomyelitis treated with combined medical and surgical treatment by a multidisciplinary team. Methods: All patients treated with surgical excision of pelvic osteomyelitis at our tertiary referral centre between 2002 and 2014 were included. All received combined care from a clinical microbiologist, an orthopaedic surgeon and a plastic surgeon. The rate of recurrent infection, wound healing problems and post-operative mortality was determined in all...
2017: Journal of bone and joint infection
https://www.readbyqxmd.com/read/29115519/pten-promotes-apoptosis-of-h2o2%C3%A2-injured-rat-nasal-epithelial-cells-through-pi3k-akt-and-other-pathways
#5
Minghui Jia, Xiaoyun Chen, Jili Liu, Jun Chen
Chronic rhinosinusitis (CRS) is a form of chronic inflammation of the nasal cavity and paranasal sinus with multi‑causal pathogenesis, including oxidative stress. Several lines of evidence have demonstrated that the phosphatase and tensin homolog gene (PTEN) can inhibit the activation of phosphoinositide 3‑kinase (PI3K) to affect phosphorylation of Akt. Importantly, the PI3K/PTEN/Akt signaling pathway is associated with various types of tumors, chronic inflammatory diseases, and autoimmune disease through its regulation of cell growth, apoptosis, proliferation, and metabolism...
October 26, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29114894/lack-of-long-term-add-on-effect-by-montelukast-in-postoperative-chronic-rhinosinusitis-patients-with-nasal-polyps
#6
Laura Van Gerven, Cristobal Langdon, Arturo Cordero, Sara Cardelús, Joaquim Mullol, Isam Alobid
OBJECTIVES/HYPOTHESIS: Eosinophils and mast cells are among the key cells in inflammatory diseases like chronic rhinosinusitis (CRS) and asthma. Leukotriene antagonists have proven to be effective in the treatment of asthma, but data about their efficacy in CRS are scarce, whereas data on montelukast as an add-on treatment to intranasal corticosteroids (INCS) in a postoperative setting are completely lacking. STUDY DESIGN: Prospective, randomized, open-label trial...
November 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29106876/early-signs-and-symptoms-of-intracranial-complications-of-otitis-media-in-pediatric-and-adult-patients-a-different-presentation
#7
N A Van der Poel, E van Spronsen, D A Dietz de Loos, F A Ebbens
OBJECTIVES: The aim of this study was to review the clinical presentation and early signs and symptoms of otogenic intracranial complications (OIC) in children and adults. METHODS: retrospective chart review. The medical records of all children and adults admitted in our center with OIC during the period 2008-2017 were reviewed. Data concerning clinical presentation, treatment and outcomes were reviewed and analyzed. RESULTS: We included 47 patients with OIC: 21 children (range 1-13 years) and 26 adults (range 22-71 years)...
November 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29101992/acr-appropriateness-criteria-%C3%A2-sinonasal-disease
#8
Claudia F E Kirsch, Julie Bykowski, Joseph M Aulino, Kevin L Berger, Asim F Choudhri, David B Conley, Michael D Luttrull, Diego Nunez, Lubdha M Shah, Aseem Sharma, Vilaas S Shetty, Rathan M Subramaniam, Sophia C Symko, Rebecca S Cornelius
Imaging of sinonasal pathology may occur for assessment of rhinosinusitis or mass lesions. Rhinosinusitis is prevalent in up to 16% of the US population with annual economic burdens estimated at 22 billion dollars. Rhinosinusitis is characterized as acute or chronic based on symptom duration; if four or more episodes occur annually, the term recurrent acute rhinosinusitis (RARS) is used. In acute uncomplicated rhinosinusitis when inflammatory change remains in the paranasal sinuses and nasal cavity, imaging may not be required...
November 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29101134/-well-it-literally-stops-me-from-having-a-life-when-it-s-really-bad-a-nested-qualitative-interview-study-of-patient-views-on-the-use-of-self-management-treatments-for-the-management-of-recurrent-sinusitis-snifs-trial
#9
Geraldine M Leydon, Lisa McDermott, Tammy Thomas, Amy Halls, Ben Holdstock-Brown, Stephen Petley, Clare Wiseman, Paul Little
OBJECTIVE: To explore the experience and perceptions of illness, the decision to consult a general practitioner and the use of self-management approaches for chronic or recurrent sinusitis. DESIGN: Qualitative semistructured interview study. SETTING: UK primary care. PARTICIPANTS: 32 participants who had been participating in the 'SNIFS' (Steam inhalation and Nasal Irrigation For recurrent Sinusitis) trial in the South of England...
November 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/29099731/update-on-pediatric-sinus-surgery-indications-and-outcomes
#10
David A Gudis, Zachary M Soler
PURPOSE OF REVIEW: To review the recent literature of pediatric endoscopic sinus surgery (ESS). RECENT FINDINGS: Sinus balloon catheter dilation is an important addition to the surgical treatment tools for pediatric chronic rhinosinusitis (PCRS). ESS is a safe and effective therapeutic modality for uncomplicated PCRS. For PCRS complicated by comorbidities including cystic fibrosis and primary ciliary dyskinesia, ESS and adjuvant medical therapy confers significant sinus, pulmonary, and quality of life benefits to pediatric patients...
December 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/29098299/safety-and-effectiveness-of-a-bioabsorbable-steroid-releasing-implant-for-the-paranasal-sinus-ostia-a-randomized-clinical-trial
#11
Amber Luong, Randall A Ow, Ameet Singh, Robert L Weiss, Joseph K Han, Roland Gerencer, J Pablo Stolovitzky, James W Stambaugh, Aarthi Raman
Importance: Suboptimal outcomes of endoscopic sinus surgery (ESS) are often associated with restenosis and inflammation of frontal sinus ostia. Steroid-releasing sinus implants have been shown to maintain sinus patency by minimizing inflammation and scar tissue formation. An hourglass-shaped, bioabsorbable, steroid-releasing implant was developed to provide mechanical support and optimize drug delivery to paranasal sinus ostia. Objective: To assess the safety and efficacy of the hourglass-shaped, bioabsorbable, steroid-releasing sinus implant in improving postoperative outcomes when placed in the frontal sinus ostia (FSO) following ESS in patients with chronic rhinosinusitis (CRS)...
November 2, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29094889/chronic-rhinosinusitis
#12
Ahmad R Sedaghat
Chronic rhinosinusitis is an inflammatory disease of the paranasal sinuses that occurs in 1% to 5% of the U.S. POPULATION: It may significantly decrease quality of life. Chronic rhinosinusitis is defined by the presence of at least two out of four cardinal symptoms (i.e., facial pain/pressure, hyposmia/anosmia, nasal drainage, and nasal obstruction) for at least 12 consecutive weeks, in addition to objective evidence. Objective evidence of chronic rhinosinusitis may be obtained on physical examination (anterior rhinoscopy, endoscopy) or radiography, preferably from sinus computed tomography...
October 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29094629/infectious-diseases-and-immunological-markers-associated-with-patients-with-non-hodgkin-lymphoma-treated-with-rituximab
#13
Kleber Jordão de Souza, Rodrigo Sala Ferro, Luiz Euribel Prestes-Carneiro, Paula Andreia Martins Carrilho, Dewton de Moraes Vasconcelos
BACKGROUND: The use of rituximab (RTX) is increasing, even in developing countries. It has become the first-line therapy or adjuvant to chemotherapy (CHOP; cyclophosphamide, hydroxydaunorubicin, oncovin and prednisone) for various diseases, including B cell lymphoma and autoimmune diseases. AIM: We describe the infectious diseases and immunological markers associated with RTX treatment of patients with non-Hodgkin lymphoma (NHL). METHODS: Serum immunoglobulins were determined before and after intravenous immunoglobulin (IVIg) administration...
November 2, 2017: Immunopharmacology and Immunotoxicology
https://www.readbyqxmd.com/read/29084007/odontogenic-sinusitis-developments-in-diagnosis-microbiology-and-treatment
#14
Alan D Workman, Eric J Granquist, Nithin D Adappa
PURPOSE OF REVIEW: Odontogenic causes of sinusitis are frequently missed; clinicians often overlook odontogenic disease whenever examining individuals with symptomatic rhinosinusitis. Conventional treatments for chronic rhinosinusitis (CRS) will often fail in odontogenic sinusitis. There have been several recent developments in the understanding of mechanisms, diagnosis, and treatment of odontogenic sinusitis, and clinicians should be aware of these advances to best treat this patient population...
October 27, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/29083530/efficacy-of-nasal-irrigation-with-200-%C3%AE-g-ml-amphotericin-b-after-functional-endoscopic-sinus-surgery-a-randomized-placebo-controlled-double-blind-study
#15
Rong-San Jiang, Chih-Wen Twu, Kai-Li Liang
BACKGROUND: Previous studies have shown controversial results of topical amphotericin B (AMB) nasal irrigation for chronic rhinosinusitis (CRS). The purpose of this study was to evaluate the efficacy of 200 μg/mL AMB nasal irrigation as an adjuvant therapy after functional endoscopic sinus surgery (FESS). METHODS: Patients with CRS who had received FESS for treatment were recruited and assigned to 1 of 2 groups at random at 1 month postsurgery. In the AMB group patients received nasal irrigation with 200 μg/mL of AMB for 2 months on a daily basis...
October 30, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29083529/evaluation-of-patient-nasal-saline-irrigation-practices-following-endoscopic-sinus-surgery
#16
Frederick Yoo, Elisabeth H Ference, Edward C Kuan, Jivianne T Lee, Marilene B Wang, Jeffrey D Suh
BACKGROUND: Functional endoscopic sinus surgery (FESS) is an effective treatment for chronic rhinosinusitis (CRS). Postoperative management strategies after FESS often vary from surgeon to surgeon. Recent data suggests that nasal saline irrigation following FESS is almost universally recommended; however, patient adherence has not been formally evaluated. The purpose of this study is to evaluate postoperative nasal irrigation practices and its effects on short-term outcomes in post-FESS patients...
October 30, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29081260/diagnostic-significance-of-serum-periostin-in-eosinophilic-chronic-sinusitis-with-nasal-polyps
#17
Ming Xu, Weiwei Zhang, Daishi Chen, Haojie Zhou, Lei Chen
OBJECTIVES: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disease. Eosinophilic CRSwNP (ENP) exhibits a strong tendency for recurrence after surgery. Given that the treatment strategy of ENP differs from that of non-eosinophilic CRSwNP (nENP), clinical diagnostic criteria that distinguish ENP from nENP are needed. METHODS: In total, 94 CRSwNP patients were enrolled in the cohort. Factors associated with ENP were determined with regression analysis, and optimal cutoff points of the predictors were determined by a receiver operating characteristic curve...
October 28, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29070267/barosinusitis-comprehensive-review-and-proposed-new-classification-system
#18
Reza Vaezeafshar, Alkis J Psaltis, Vidya K Rao, David Zarabanda, Zara M Patel, Jayakar V Nayak
BACKGROUND: Barosinusitis, or sinus barotrauma, may arise from changes in ambient pressure that are not compensated by force equalization mechanisms within the paranasal sinuses. Barosinusitis is most commonly seen with barometric changes during flight or diving. Understanding and better classifying the pathophysiology, clinical presentation, and management of barosinusitis are essential to improve patient care. OBJECTIVES: To perform a comprehensive review of the available literature regarding sinus barotrauma...
October 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/29059083/current-opinions-in-office-based-rhinology
#19
Aykut A Unsal, Naomi Gregory, Kenneth Rosenstein
PURPOSE OF REVIEW: The care of rhinologic patients has undergone a remarkable transformation in recent years. With the advent of endoscopic sinus surgery and high-tech image-guided computer systems, the surgical care of patients with benign sinonasal disease has successfully transitioned from the main hospital operating room to the outpatient ambulatory surgical center. Currently, there is yet another movement underway, in an attempt to care for these patients in the office setting. RECENT FINDINGS: As the medical device sector continues to innovate at rapid speed, new technologies such as the radiofrequency ablator, microdebrider, balloon sinus dilator, and steroid-eluting stent have propelled the care of rhinologic patients into the clinic setting...
October 20, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/29058098/osteomyelitis-of-the-lower-extremity-pathophysiology-imaging-and-classification-with-an-emphasis-on-diabetic-foot-infection
#20
Jacob C Mandell, Bharti Khurana, Jeremy T Smith, Gregory J Czuczman, Varand Ghazikhanian, Stacy E Smith
Osteomyelitis is inflammation of the bone caused by an infectious organism, and is a difficult clinical problem. The pathophysiology, imaging, and classification of osteomyelitis are challenging, varying with the age of the patient (child versus adult), the chronicity of the infection (acute versus chronic), and the route of spread (hematogenous versus contiguous focus), as well as the immune and vascular status of the patient and affected region. The two most common classification schemes are those of Lew and Waldvogel, and Cierny and Mader...
October 20, 2017: Emergency Radiology
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