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https://www.readbyqxmd.com/read/28549275/understanding-the-relationships-between-water-quality-recreational-fishing-practices-and-human-health-in-phoenix-arizona
#1
E Pulford, B A Polidoro, M Nation
Across the United States, recreational freshwater fisheries are not only an important leisure activity, but can also provide a relatively inexpensive source of protein in local diets. However, recreational freshwater fisheries are generally not well-monitored in terms of fish consumption vs. catch and release, nor are all recreational surface waters regularly monitored for the presence of potentially harmful contaminants in water or fishes. In six urban lakes that support recreational fisheries in Phoenix, Arizona, a majority of surveyed anglers reported eating recreationally caught fishes, even though they thought the water might be polluted...
May 23, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28549272/acute-toxicity-of-emerging-atmospheric-pollutants-from-wood-lignin-due-to-biomass-burning
#2
Maryline Pflieger, Ana Kroflič
Guaiacol (2-methoxyphenol) is an important atmospheric pollutant. It is the major component of wood lignin and is essentially emitted to the atmosphere during biomass burning. Its aging in the tropospheric aqueous phase leads to the generation of the following ring-retaining transformation products, also during nighttime: 4-nitroguaiacol, 6-nitroguaiacol, and dinitroguaiacol. This study presents the first toxicological data of guaiacol and its nitro derivatives and reveals their harmful potential for the ecosystem...
May 15, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28549211/chronic-sinonasal-tract-inflammation-as-a-precursor-to-nasopharyngeal-carcinoma-and-sinonasal-malignancy-in-the-united-states
#3
Eric L Wu, Charles A Riley, Mei-Chin Hsieh, Michael J Marino, Xiao-Cheng Wu, Edward D McCoul
BACKGROUND: Chronic inflammatory states have been linked to the development of malignancy. Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) have been associated with nasopharyngeal carcinoma (NPC) in population-based studies in Asia. A similar association with NPC and paranasal sinus malignancy (PSM) has not been defined in a North American population. Our purpose was to investigate the impact of CRS and AR on the risk of NPC and PSM. METHODS: The Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database was queried as a case-control study of adults ≥65 years of age...
May 23, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28549161/cigarette-smoking-cessation-intervention-for-buprenorphine-treatment-patients
#4
Sharon M Hall, Gary Humfleet, James Gasper, Kevin L Delucchi, David Hersh, Joseph Guydish
Introduction: Patients receiving Medication Assisted Therapy (MAT) for opioid use disorder have high cigarette smoking rates. Cigarette smoking interventions have had limited success. We evaluated an intervention to increase cigarette abstinence rates in patients receiving buprenorphine-assisted therapy. Methods: Cigarette smokers (N=175; 78% male; 69% Caucasian; 20% Hispanic), recruited from a buprenorphine clinic were randomly assigned to either an extended innovative system intervention (E-ISI) or to Standard Treatment Control (STC)...
May 26, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28549156/early-subjective-sensory-experiences-with-cigalike-e-cigarettes-among-african-american-menthol-smokers-a-qualitative-study
#5
Sabrina L Smiley, Teresa DeAtley, Leslie F Rubin, Emily Harvey, Elexis C Kierstead, Monica Webb Hooper, Raymond S Niaura, David B Abrams, Jennifer L Pearson
Introduction: Despite smoker interest in e-cigarettes as a harm reduction or cessation aid, many smokers prematurely discontinue vaping after trying a product. This study explored the role of early subjective sensory experience in vaping persistence and desistence. Methods: African American menthol cigarette smokers aged ≥18 years (n=15; M=54.1 years; SD=8.2), motivated to quit smoking, and interested in trying e-cigarettes were recruited in Washington, D.C. Participants were followed for three weeks and provided menthol cigalike e-cigarettes after week one...
May 26, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28548905/brca-associated-cancers-role-of-imaging-in-screening-diagnosis-and-management
#6
Michelle V Lee, Venkata S Katabathina, Michyla L Bowerson, Marina I Mityul, Anup S Shetty, Khaled M Elsayes, Aparna Balachandran, Priya R Bhosale, Ann E McCullough, Christine O Menias
Harmful mutations of the BRCA tumor suppressor genes result in a greater lifetime risk for malignancy-breast and ovarian cancers in particular. An increased risk for male breast, fallopian tube, primary peritoneal, pancreatic, prostate, and colon cancers also has been reported. The BRCA gene is inherited in an autosomal dominant pattern and tends to be highly penetrant; thus, there is an increased incidence of these cancers in affected families. Compared with sporadic tumors, BRCA-associated malignancies have unique manifestations, clinical features, and pathologic profiles...
May 26, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28548699/cytocompatibility-physical-properties-and-antibiofilm-activity-of-endodontic-sealers-with-amoxicillin
#7
Carolina Andolfatto, Idomeo Bonetti-Filho, Iracilda Zeppone Carlos, Juliane Maria Guerreiro-Tanomaru, Milton Carlos Kuga, Fernanda Borges Cunha Tormin, Gisele Faria
The aim was to evaluate the cytocompatibility of the AH Plus and Sealapex associated with amoxicillin (AA) in a quantity of 10% by total weight of the sealers, the flow and setting time of these sealers with 10%-0.25% AA and antibiofilm activity of these sealers associated with AA in a concentration that does not alter their physical properties (1%). Cytocompatibility was assessed by MTT, neutral red and cytoskeletal fluorescence assays. Setting time and flow was evaluated using the specifications of ISO 6876/2012...
May 26, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28548613/recommendations-for-research-on-suicide-loss-a-commentary
#8
Robert A Neimeyer, Julie Cerel, Myfanwy Maple
As detailed in the lead article in this Special Issue, the Survivors of Suicide Loss Task Force of the National Action Alliance for Suicide Prevention in the United States has recently worked to formulate national guidelines to mitigate the harmful after-effects of suicide in social and family systems. In the present article, we elaborate on one of four strategic directions addressed by the Task Force, namely the development of goals and objectives for surveillance, research and evaluation of the impact of suicide loss...
May 26, 2017: Death Studies
https://www.readbyqxmd.com/read/28548282/estimating-the-effect-of-immortal-time-bias-in-urologic-research-a-case-example-of-testosterone-replacement-therapy
#9
Christopher J D Wallis, Refik Saskin, Steven A Narod, Calvin Law, Girish S Kulkarni, Arun Seth, Robert K Nam
OBJECTIVE: To quantify the effect of immortal-time bias in an observational study examining the effect of cumulative testosterone exposure on mortality. SUBJECTS AND METHODS: We used a population-based matched cohort study of men aged 66 and older newly treated with testosterone replacement therapy and matched-controls from 2007-2012 in Ontario, Canada to quantify the effects of immortal-time bias. We used generalized estimating equations to determine the association between cumulative testosterone replacement therapy exposure and mortality...
May 26, 2017: BJU International
https://www.readbyqxmd.com/read/28548184/obesity-and-kidney-disease-hidden-consequences-of-the-epidemic
#10
Csaba P Kovesdy, Susan Furth, Carmine Zoccali
Obesity has become a worldwide epidemic, and its prevalence has been projected to grow by 40% in the next decade. This increasing prevalence has implications for the risk of diabetes, cardiovascular disease and also for Chronic kidney disease. A high body mass index is one of the strongest risk factors for new-onset Chronic kidney disease. In individuals affected by obesity, a compensatory hyperfiltration occurs to meet the heightened metabolic demands of the increased body weight. The increase in intraglomerular pressure can damage the kidneys and raise the risk of developing Chronic kidney disease in the long-term...
March 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28547943/assertions-of-japanese-websites-for-and-against-cancer-screening-a-text-mining-analysis
#11
Tsuyoshi Okuhara, Hirono Ishikawa, Masahumi Okada, Mio Kato, Takahiro Kiuchi
Background: Cancer screening rates are lower in Japan than in Western countries such as the United States and the United Kingdom. While health professionals publish pro-cancer-screening messages online to encourage proactive seeking for screening, anti-screening activists use the same medium to warn readers against following guidelines. Contents of pro- and anti-cancer-screening sites may contribute to readers’ acceptance of one or the other position. We aimed to use a text-mining method to examine frequently appearing contents on sites for and against cancer screening...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28547663/pediatric-predispositional-genetic-risk-communication-potential-utility-for-prevention-and-control-of-melanoma-risk-as-an-exemplar
#12
Yelena P Wu, Darren Mays, Wendy Kohlmann, Kenneth P Tercyak
Predispositional genetic testing among minor children is intensely debated due to the potential benefits and harms of providing this type of genetic information to children and their families. Existing guidelines on pediatric genetic testing state that predispositional testing could be appropriate for minors if preventive services exist that mitigate children's risk for or severity of the health condition in question. We use the example of hereditary melanoma to illustrate the rationale for and potential application of genetic risk communication for an adult-onset cancer to a pediatric population where childhood behaviors may reduce risk of disease later in life...
May 25, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28547568/biofertilizers-and-sustainable-agriculture-exploring-arbuscular-mycorrhizal-fungi
#13
REVIEW
Nicholas O Igiehon, Olubukola O Babalola
Worldwide agricultural food production has to double in 2050 so as to feed the global increasing population while reducing dependency on conventional chemical fertilizers plus pesticides. To accomplish this objective, there is the need to explore the several mutualistic interactions between plant roots and rhizosphere microbiome. Biofertilization is the process of boosting the abundance of microorganisms such as arbuscular mycorrhizal fungi (AMF) in the natural plant rhizosphere which depicts a beneficial alternative to chemical fertilization practices...
May 25, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28546766/abcb1-genetic-variants-in-leukemias-current-insights-into-treatment-outcomes
#14
REVIEW
Ravindran Ankathil
Despite improvements in treatment of different types of leukemia, not all patients respond optimally for a particular treatment. Some treatments will work better for some, while being harmful or ineffective for others. This is due to genetic variation in the form of single-nucleotide polymorphisms (SNPs) that affect gene expression or function and cause inherited interindividual differences in the metabolism and disposition of drugs. Drug transporters are one of the determinants governing the pharmacokinetic profile of chemotherapeutic drugs...
2017: Pharmacogenomics and Personalized Medicine
https://www.readbyqxmd.com/read/28546594/patient-safety-reducing-the-risk-of-wrong-tooth-extraction
#15
P Cullingham, A Saksena, M N Pemberton
Over recent years there has been an increased emphasis on improving patient safety in all branches of medicine, with reducing wrong tooth extraction being a priority in dentistry. The true incidence of wrong tooth extraction is unknown but it is considered an avoidable harm and is a significant source of dental litigation. Interventions to reduce wrong tooth extraction include educational programmes encompassing human factor training, patient assisted identification, the use of checklists, marking of surgical sites and implementation of patient safety guidelines...
May 26, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28546138/mental-health-mobile-apps-for-preadolescents-and-adolescents-a-systematic-review
#16
REVIEW
Rebecca Grist, Joanna Porter, Paul Stallard
BACKGROUND: There are an increasing number of mobile apps available for adolescents with mental health problems and an increasing interest in assimilating mobile health (mHealth) into mental health services. Despite the growing number of apps available, the evidence base for their efficacy is unclear. OBJECTIVE: This review aimed to systematically appraise the available research evidence on the efficacy and acceptability of mobile apps for mental health in children and adolescents younger than 18 years...
May 25, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28546136/an-ecological-momentary-intervention-to-reduce-alcohol-consumption-in-young-adults-delivered-during-drinking-events-protocol-for-a-pilot-randomized-controlled-trial
#17
Cassandra Jc Wright, Paul M Dietze, Paul A Agius, Emmanuel Kuntsche, Robin Room, Michael Livingston, Margaret Hellard, Megan Sc Lim
BACKGROUND: Risky drinking is a significant public health issue in young Australian adults. Brief interventions are one of few effective methods of reducing risky drinking but are time and cost intensive; innovative methods of delivery are therefore of interest. Mobile phones offer new opportunities to collect data and intervene during risky drinking events. Mobile phones have successfully been used for delivery of alcohol-related brief interventions and data collection but not in combination with or during drinking events...
May 25, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28546112/pemphigus-vulgaris-induced-by-5-aminolaevulinic-acid-based-photodynamic-therapy
#18
Qian Zhou, Peiru Wang, Linglin Zhang, Bo Wang, Lei Shi, Uma Keyal, Anil Kumar Bhatta, Guolong Zhang, Xiuli Wang
Pemphigus vulgaris (PV) is an autoimmune disorder resulting from the interaction between autoantibodies and desmoglein. Here, we report a case of PV developed after 5-aminolaevulinic acid-based photodynamic therapy (ALA-PDT). The harmful and deleterious effects of UV radiation on the onset, during course, and perpetuation of PV have been observed for decades. Correlation between reactive oxygen species (ROS) and PV have also been reported. Oxidative proteins, which are modified by ROS, and subsequent production of antibodies by immune system seem to be responsible for PV developed following ALA-PDT...
May 22, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28546045/intravenous-targeted-microbubbles-carrying-urokinase-versus-urokinase-alone-in-acute-peripheral-arterial-thrombosis-in-a-porcine-model
#19
Johanna H Nederhoed, Harm P Ebben, Jeroen Slikkerveer, Arjan Wj Hoksbergen, Otto Kamp, Geert-Jan Tangelder, Willem Wisselink, René Jp Musters, Kak K Yeung
PURPOSE: Standard therapy in acute peripheral arterial occlusion consists of intra-arterial catheter guided thrombolysis. As microbubbles may be used as a carrier for fibrinolytic agents and targeted to adhere to the thrombus, we can theoretically deliver the thrombolytic medication locally following simple intravenous injection. In this intervention-controlled feasibility study, we compared intravenously administered targeted microbubbles incorporating Urokinase and locally applied ultrasound, with intravenous Urokinase and ultrasound alone...
May 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28545961/pecc-correcting-contigs-based-on-paired-end-read-distribution
#20
Min Li, Binbin Wu, Xiaodong Yan, Junwei Luo, Yi Pan, Fang-Xiang Wu, Jianxin Wang
MOTIVATION: Cheap and fast next generation sequencing (NGS) technologies facilitate research of de novo assembly greatly. The reliability of contigs is critical to construct reliable scaffolding. However, contigs generated from most assemblers contain errors because of the limitation of assembly strategy and computation complexity. Among all these errors, the misassembly error is one of the most harmful types. RESULTS: In this paper, we propose a new method named "PECC" to identify and correct misassembly errors in contigs based on the paired-end read distribution...
May 1, 2017: Computational Biology and Chemistry
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