Yujie Huang, Daitian Zheng, Zhongming Zhou, Haiting Wang, Yanpo Li, Huihui Zheng, Jianhui Tan, Jingyao Wu, Qiuping Yang, Huiting Tian, Liuming Lin, Zhiyang Li, Tianyu Li
INTRODUCTION: Cancer represents a significant global public health concern. In recent years, the incidence of cancer has been on the rise worldwide due to various factors, including diet, environment, and an aging population. Simultaneously, advancements in tumor molecular biology and genomics have led to a shift from systemic chemotherapy focused on disease sites and morphopathology towards precise targeted therapy for driver gene mutations. Therefore, we propose a comprehensive review aimed at exploring the research hotspots and directions in the field of Kirsten rat sarcoma viral oncogene homolog ( KRAS )-mutant cancers over the past decade, providing valuable insights for cancer treatment strategies...
2024: Frontiers in Oncology