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Acute pulmonary oedema

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https://www.readbyqxmd.com/read/29903755/severity-scoring-of-lung-oedema-on-the-chest-radiograph-is-associated-with-clinical-outcomes-in-ards
#1
Melissa A Warren, Zhiguou Zhao, Tatsuki Koyama, Julie A Bastarache, Ciara M Shaver, Matthew W Semler, Todd W Rice, Michael A Matthay, Carolyn S Calfee, Lorraine B Ware
BACKGROUND: There is no accurate, non-invasive measurement to estimate the degree of pulmonary oedema in acute respiratory distress syndrome (ARDS). We developed the Radiographic Assessment of Lung Oedema (RALE) score to evaluate the extent and density of alveolar opacities on chest radiographs. After first comparing the RALE score to gravimetric assessment of pulmonary oedema in organ donors, we then evaluated the RALE score in patients with ARDS for its relationship to oxygenation and clinical outcomes...
June 14, 2018: Thorax
https://www.readbyqxmd.com/read/29899670/-perspective-review-type-2-diabetes-and-readmission-for-heart-failure
#2
Merlin C Thomas
Heart failure is a leading cause for hospitalisation and for readmission, especially in patients over the age of 65. Diabetes is an increasingly common companion to heart failure. The presence of diabetes and its associated comorbidity increases the risk of adverse outcomes and premature mortality in patients with heart failure. In particular, patients with diabetes are more likely to be readmitted to hospital soon after discharge. This may partly reflect the greater severity of heart disease in these patients...
2018: Clinical Medicine Insights. Cardiology
https://www.readbyqxmd.com/read/29895721/changes-in-the-ev-a71-genome-through-recombination-and-spontaneous-mutations-impact-on-virulence
#3
REVIEW
Madiiha Bibi Mandary, Chit Laa Poh
Enterovirus 71 (EV-A71) is a major etiological agent of hand, foot and mouth disease (HFMD) that mainly affects young children less than five years old. The onset of severe HFMD is due to neurological complications bringing about acute flaccid paralysis and pulmonary oedema. In this review, we address how genetic events such as recombination and spontaneous mutations could change the genomic organization of EV-A71, leading to an impact on viral virulence. An understanding of the recombination mechanism of the poliovirus and non-polio enteroviruses will provide further evidence of the emergence of novel strains responsible for fatal HFMD outbreaks...
June 12, 2018: Viruses
https://www.readbyqxmd.com/read/29844037/acute-non-cardiogenic-pulmonary-oedema-due-to-contralateral-pulmonary-re-expansion-after-thoracentesis-an-uncommon-complication
#4
Rita Gomes, Bruno Rocha, Rui Morais, Inês Araújo
No abstract text is available yet for this article.
May 29, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29780817/clinical-profile-and-outcome-of-patients-with-acute-kidney-injury-requiring-hemodialysis-two-years-experience-at-a-tertiary-hospital-in-rwanda
#5
Grace Igiraneza, Benedicte Ndayishimiye, Menelas Nkeshimana, Vincent Dusabejambo, Onyema Ogbuagu
Introduction: Acute kidney injury (AKI) requiring renal replacement therapy is associated with high mortality. The study assessed the impact of the introduction of hemodialysis (HD) on outcomes of patients with AKI in Rwanda. Methods: A single center retrospective study that evaluated the clinical profile and survival outcomes of patients with AKI requiring HD [AKI-D] at a tertiary hospital in Rwanda. Data was collected on patients who received HD for AKI from September 2014 to December 2016...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29691755/my-patient-has-received-fluid-how-to-assess-its-efficacy-and-side-effects
#6
REVIEW
Xavier Monnet, Jean-Louis Teboul
Many efforts have been made to predict, before giving fluid, whether it will increase cardiac output. Nevertheless, after fluid administration, it is also essential to assess the therapeutic efficacy and to look for possible adverse effects. Like for any drug, this step should not be missed. Basically, volume expansion is aimed at improving tissue oxygenation and organ function. To assess this final result, clinical signs are often unhelpful. The increase in urine output in case of acute kidney injury is a poor marker of the kidney perfusion improvement...
April 24, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29674403/unexpected-case-of-pneumomediastinum-and-subcutaneous-emphysema-primary-or-secondary-aetiology
#7
Amanda J L Cheng, Timothy J Sadler
A 77-year-old man was admitted with a relapse of antineutrophil cytoplasmic antibody-positive vasculitis with pulmonary involvement and acute kidney injury. There was a background of pulmonary fibrosis (non-specific interstitial pneumonia type pattern) and superadded pulmonary haemorrhage, acute pulmonary oedema and sepsis. The patient was intubated for 4 days and remained dependent on high flow oxygen and continuous positive airway pressure after extubation. A chest radiograph performed 2 weeks after extubation demonstrated unexpected, extensive pneumomediastinum and subcutaneous emphysema...
April 19, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29628684/thirty-day-mortality-following-total-knee-arthroplasty-over-7-years-at-a-tertiary-referral-centre-of-orthopaedic-excellence
#8
Yuen Chan, Veenesh Selvaratnam, Videsh Raut
Total Knee Arthroplasty (TKA) is one of the most successful orthopaedic procedures. Around 100,000 TKAs are performed yearly in the United Kingdom. The aim of this study was to report the mortality rate within 30 days after a TKA in an Orthopaedic Centre of Excellence. We reviewed prospectively collected data of 7067 TKAs performed between April 2009-November 2016. All mortalities within 30 days of a TKA were recorded. Data such as age, sex, ASA, comorbidities and cause of death was recorded. There were 14 (0...
January 2018: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29602671/dover-sole
#9
Joaquín Valle Alonso, Shane Tucker, Ganapathiram Lakshmanan, Adan Stokes
Negative pressure pulmonary edema (NPPE) is a clinical syndrome well described in the literature and easy to recognize in cases of suspicion, but probably underdiagnosed. It can be a cause of morbidity and admission to the intensive care unit of healthy young individuals. It is present in approximately one in every thousand anesthetics and in 10% of the episodes of upper airway obstruction that are observed in routine clinical practice. It is a non-cardiogenic form of pulmonary oedema thought to be caused by the highly negative intra-thoracic pressure generated when trying to breathe against an acute obstruction...
March 21, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29576114/effect-of-goal-directed-haemodynamic-therapy-on-postoperative-complications-in-low-moderate-risk-surgical-patients-a-multicentre-randomised-controlled-trial-fedora-trial
#10
J M Calvo-Vecino, J Ripollés-Melchor, M G Mythen, R Casans-Francés, A Balik, J P Artacho, E Martínez-Hurtado, A Serrano Romero, C Fernández Pérez, S Asuero de Lis
BACKGROUND: The aim of this study was to evaluate postoperative complications in patients having major elective surgery using oesophageal Doppler monitor-guided goal-directed haemodynamic therapy (GDHT), in which administration of fluids, inotropes, and vasopressors was guided by stroke volume, mean arterial pressure, and cardiac index. METHODS: The FEDORA trial was a prospective, multicentre, randomised, parallel-group, controlled patient- and observer-blind trial conducted in adults scheduled for major elective surgery...
April 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29557101/immersion-pulmonary-oedema-in-a-healthy-diver-not-exposed-to-cold-or-strenuous-exercise
#11
Olivier Castagna, Sébastien de Maistre, Bruno Schmid, Delphine Caudal, Jacques Regnard
In healthy divers, the occurrence of immersion pulmonary oedema (IPE) is commonly caused by contributory factors including strenuous exercise, cold water and negative-pressure breathing. Contrary to this established paradigm, this case reports on a 26-year-old, well-trained combat swimmer who succumbed to acute IPE during static immersion in temperate (21°C) water, while using a front-mounted counterlung rebreather. The incident occurred during repeated depth-controlled ascent practice at the French military diving school...
March 31, 2018: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/29545281/pulmonary-vascular-endothelium-the-orchestra-conductor-in-respiratory-diseases-highlights-from-basic-research-to-therapy
#12
REVIEW
Alice Huertas, Christophe Guignabert, Joan A Barberà, Peter Bärtsch, Jahar Bhattacharya, Sunita Bhattacharya, Maria R Bonsignore, Laurence Dewachter, Anh Tuan Dinh-Xuan, Peter Dorfmüller, Mark T Gladwin, Marc Humbert, Tom Kotsimbos, Theodoros Vassilakopoulos, Olivier Sanchez, Laurent Savale, Ugo Testa, Martin R Wilkins
The European Respiratory Society (ERS) Research Seminar entitled "Pulmonary vascular endothelium: orchestra conductor in respiratory diseases - highlights from basic research to therapy" brought together international experts in dysfunctional pulmonary endothelium, from basic science to translational medicine, to discuss several important aspects in acute and chronic lung diseases. This review will briefly sum up the different topics of discussion from this meeting which was held in Paris, France on October 27-28, 2016...
April 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29529715/interventions-for-preventing-high-altitude-illness-part-2-less-commonly-used-drugs
#13
REVIEW
Alejandro Gonzalez Garay, Daniel Molano Franco, Víctor H Nieto Estrada, Arturo J Martí-Carvajal, Ingrid Arevalo-Rodriguez
BACKGROUND: High altitude illness (HAI) is a term used to describe a group of mainly cerebral and pulmonary syndromes that can occur during travel to elevations above 2500 metres (˜ 8200 feet). Acute mountain sickness (AMS), high altitude cerebral oedema (HACE) and high altitude pulmonary oedema (HAPE) are reported as potential medical problems associated with high altitude ascent. In this second review, in a series of three about preventive strategies for HAI, we assessed the effectiveness of five of the less commonly used classes of pharmacological interventions...
March 12, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29506544/experimental-malaria-associated-acute-respiratory-distress-syndrome-is-dependent-on-the-parasite-host-combination-and-coincides-with-normocyte-invasion
#14
Leen Vandermosten, Thao-Thy Pham, Hendrik Possemiers, Sofie Knoops, Evelien Van Herck, Julie Deckers, Blandine Franke-Fayard, Tracey J Lamb, Chris J Janse, Ghislain Opdenakker, Philippe E Van den Steen
BACKGROUND: Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a complication of malaria with a lethality rate of up to 80% despite anti-malarial treatment. It is characterized by a vast infiltration of leukocytes, microhaemorrhages and vasogenic oedema in the lungs. Previously, a mouse model for MA-ARDS was developed by infection of C57BL/6 mice with the Edinburgh line NK65-E of Plasmodium berghei. RESULTS: Here, both host and parasite factors were demonstrated to play crucial roles in the development and severity of lung pathology...
March 5, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29423196/renal-recovery-after-severe-acute-kidney-injury-in-critically-ill-myeloma-patients-a-retrospective-study
#15
Adrien Joseph, Stephanie Harel, Marion Venot, Sandrine Valade, Eric Mariotte, Claire Pichereau, Akli Chermak, Lara Zafrani, Elie Azoulay, Emmanuel Canet
Background: Despite substantial improvements in the management of multiple myeloma, renal failure remains an important burden that tremendously impairs prognosis. The purpose of this study was to describe the characteristics and to establish prognostic factors of renal recovery in myeloma patients admitted to the intensive care unit (ICU) for acute kidney injury (AKI) Stage 3 treated with renal replacement therapy (RRT). Methods: A retrospective single-centre cohort study was performed, including consecutive myeloma patients admitted to one medical ICU between 1 January 2007 and 1 September 2015 and treated with RRT...
February 2018: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29420246/ards-complicating-pustular-psoriasis-treatment-with-low-dose-corticosteroids-vitamin-c-and-thiamine
#16
Paul Ellis Marik, Ashleigh Long
We report the case of a 45-year-old Caucasian woman with a history of psoriasis, admitted to our Medical intensive care unit following the acute onset of diffuse rash and progressive dyspnoea and hypoxaemia requiring escalating respiratory support (continuous positive airway pressure of 10 cm H2 O). Her chest X-ray was consistent with findings of non-cardiogenic pulmonary oedema. Echocardiogram was normal. Dermatology considered her skin lesions to be consistent with psoriasis vulgaris with pustular flare. In the absence of an identifiable cause for her respiratory failure, she was diagnosed with acute respiratory distress syndrome due to her psoriatic flare...
February 2, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29374634/neurogenic-pulmonary-oedema-secondary-to-vertebral-artery-dissection-while-playing-tennis
#17
Manaf Aljishi, Sisira Jayathissa
We present a case of a patient who developed vertebral artery dissection (VAD) while playing tennis and presented with neurogenic pulmonary oedema. The case highlights two important points: acute pulmonary oedema as an unusual presenting feature of VAD and VAD, an important cause of stroke in young people, as being associated with playing low-impact sports such as tennis. These associations, independent of each other, are under-recognised and can lead to a delay in diagnosis.
January 26, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29355691/civilian-exposure-to-chlorine-gas-a-systematic-review
#18
P Govier, J M Coulson
INTRODUCTION: Halogen pulmonary irritants (HPIs) are volatile liquids that directly damage the respiratory mucosa. Chlorine is readily available in large volumes as an industrial chemical and has a significant potential for accidental or deliberate release. We conducted a systematic review to determine the clinical features; treatment and long-term sequelae of civilian chlorine gas exposure. METHODS: A systematic review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology...
January 19, 2018: Toxicology Letters
https://www.readbyqxmd.com/read/29337267/acute-lung-injury-induced-by-intestinal-ischemia-and-reperfusion-is-altered-in-obese-female-mice
#19
Evelyn Thais Fantozzi, Sara Rodrigues-Garbin, Fernanda Yamamoto Ricardo-da-Silva, Ricardo Martins Oliveira-Filho, Domenico Spina, Wothan Tavares-de-Lima, Yanira Riffo-Vasquez
RATIONAL: Acute lung injury (ALI) is a common complication after intestinal ischemia and reperfusion (I/R) injury that can lead to acute respiratory distress syndrome (ARDS). We have previously demonstrated that females are protected against lung damage induced by intestinal I/R through an estrogen mediated mechanism. OBJECTIVES: To investigate the effect of obesity on ALI induced by intestinal I/R in female mice. METHODS: C57Bl/6 female mice were fed with a standard low-fat diet (SD) or a high-fat diet (HFD) for 9 weeks...
April 2018: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29311434/suspected-lily-toxicosis-in-a-meerkat-suricata-suricatta-a-case-report
#20
Kiyokazu Ozaki, Masakazu Hirabayashi, Koji Nomura, Isao Narama
Lilies are considered nephrotoxic only to domestic cats, which belong to the family Felidae of the suborder Feliformia. However, a 7-month-old female meerkat, belonging to the family Herpestidae of the suborder Feliformia, presented with oliguria, seizure, tachypnea, self-biting, and nystagmus after it ingested lilies. The meerkat died approximately 40 hr after lily ingestion. Gross and histopathologic lesions consistent with acute renal failure were conspicuous in the animal. The renal lesions were acute tubular necrosis, corresponding to the typical pathological changes of lily toxicosis in cats...
March 24, 2018: Journal of Veterinary Medical Science
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