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Acute pulmonary oedema

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https://www.readbyqxmd.com/read/28513396/acute-pulmonary-oedema
#1
Sue Wrigglesworth
What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The article provided information about the pathology, recognition, assessment and management of acute pulmonary oedema.
May 17, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28512854/mogroside-iiie-attenuates-lps-induced-acute-lung-injury-in-mice-partly-through-regulation-of-the-tlr4-mapk-nf-%C3%AE%C2%BAb-axis-via-ampk-activation
#2
Lijun Tao, Fengyan Cao, Gonghao Xu, Haifeng Xie, Mian Zhang, Chaofeng Zhang
Acute lung injury (ALI) often leads to high mortality, and there is as yet no effective drug treatment. The present study aimed to investigate protective effects of mogroside IIIE (MGIIIE, a cucurbitane-type triterpenoid from Siraitia grosvenorii Fruits) in experimental ALI and its underlying mechanism. MGIIIE (1, 10 0r 20 mg/kg) was orally administered for 1 h before a single intratracheal administration of lipopolysaccharide (LPS, 5 mg/kg). MGIIIE treatment dose-dependently suppressed pulmonary oedema, pro-inflammatory mediators (IL-1β, IL-6, TNF-α and HMGB1) release and higher MPO activity in lung tissues induced by LPS challenge...
May 17, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28507398/managing-acute-pulmonary-oedema
#3
REVIEW
Megan Purvey, George Allen
No abstract text is available yet for this article.
April 2017: Australian Prescriber
https://www.readbyqxmd.com/read/28463462/clinical-phenotypes-and-outcome-of-patients-hospitalized-for-acute-heart-failure-the-esc-heart-failure-long-term-registry
#4
Ovidiu Chioncel, Alexandre Mebazaa, Veli-Pekka Harjola, Andrew J Coats, Massimo Francesco Piepoli, Maria G Crespo-Leiro, Cecile Laroche, Petar M Seferovic, Stefan D Anker, Roberto Ferrari, Frank Ruschitzka, Silvia Lopez Fernandez, Daniela Miani, Gerasimos Filippatos, Aldo P Maggioni
AIMS: To identify differences in clinical epidemiology, in-hospital management and 1-year outcomes among patients hospitalized for acute heart failure (AHF) and enrolled in the European Society of Cardiology Heart Failure Long-Term (ESC-HF-LT) Registry, stratified by clinical profile at admission. METHODS AND RESULTS: The ESC-HF-LT Registry is a prospective, observational study collecting hospitalization and 1-year follow-up data from 6629 AHF patients. Among AHF patients enrolled in the registry, 13...
April 30, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28451456/immunosuppressive-treatment-in-fulminant-myocarditis-and-gene-expression-pattern-associated-with-but-no-histological-confirmation-of-giant-cell-myocarditis
#5
Friedrich Fruhwald, Dirk Lassner, Sonja Fruhwald, Ulrich M Gross, Otto Dapunt, Heinz-Peter Schultheiss
A healthy woman with acute onset of pulmonary oedema and severely depressed left ventricular function underwent endomyocardial biopsy under the clinical suspicion of fulminant myocarditis. While awaiting the results of biopsy, the situation deteriorated to Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) and extracorporeal membrane oxygenation was implanted. Finally, immunohistochemistry in biopsy specimen corresponded to fulminant lymphocytic myocarditis, although active myocarditis was excluded...
May 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28450654/left-circumflexus-coronary-artery-total-occlusion-with-clinical-presentation-as-nstemi-and-acute-pulmonary-oedema
#6
Budi Yuli Setianto, Nahar Taufiq, Heri Hernawan
Current guidelines for the management of patients with acute coronary syndromes (ACSs) focus on the electrocardiogram to divide patients into ST-elevation acute myocardial infarction (STEMI) or non-ST-elevation acute myocardial infarction (NSTEMI)/unstable angina (UA). Patients with STEMI in the earliest time will receive reperfusion therapy to destruct occlusive thrombus. An ST segment elevation is the 'sine qua non' for diagnosing acute total coronary occlusion causing transmural myocardial infarction. Left circumflex coronary artery (LCx) occlusion is often categorized as NSTEMI because of the absence of significant ST-elevation on the 12 lead standard electrocardiogram...
January 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/28339702/subclinical-chronic-left-ventricular-systolic-dysfunction-resulting-from-phosphine-poisoning
#7
E Szymczyk, M Wiszniewska, J Walusiak-Skorupa, J D Kasprzak, P Lipiec
We present a case of a 32-year-old male crew member of a cargo ship, accidentally exposed to phosphine, a fumigating substance. He and other crew members developed increasing fatigue and digestive disorders 24 h later; two died from acute pulmonary oedema. The patient was admitted to hospital, where bilateral pneumonia, acute nephritis, hepatopathy, electrolyte imbalance and leucopenia were diagnosed. He was discharged from hospital 3 weeks later. He was examined 4 months later for possible chronic consequences of acute phosphine poisoning, which included echocardiography showing normal heart size and cardiac function...
February 21, 2017: Occupational Medicine
https://www.readbyqxmd.com/read/28258847/percutaneous-edge-to-edge-mitral-valve-repair-for-the-treatment-of-acute-mitral-regurgitation-complicating-myocardial-infarction-a-single-centre-experience
#8
Marianna Adamo, Salvatore Curello, Ermanna Chiari, Claudia Fiorina, Giuliano Chizzola, Marco Magatelli, Elisa Locantore, Giovanni Cuminetti, Carlo Lombardi, Aldo Manzato, Marco Metra, Federica Ettori
BACKGROUND: Limited evidence is available about MitraClip therapy in patients with acute mitral regurgitation (MR) complicating myocardial infarction (MI). METHODS AND RESULTS: Among 80 consecutive patients undergoing MitraClip treatment, 5 (6.3%) had been admitted for acute MI complicated by severe MR. Mean age was 73±6years and 3 were males. At the time of admission they were in cardiogenic shock (80%) or pulmonary oedema (20%), with severe MR, left ventricular dysfunction and pulmonary hypertension...
May 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28253375/genomic-and-phenotypic-characterization-of-myxoma-virus-from-great-britain-reveals-multiple-evolutionary-pathways-distinct-from-those-in-australia
#9
Peter J Kerr, Isabella M Cattadori, Matthew B Rogers, Adam Fitch, Adam Geber, June Liu, Derek G Sim, Brian Boag, John-Sebastian Eden, Elodie Ghedin, Andrew F Read, Edward C Holmes
The co-evolution of myxoma virus (MYXV) and the European rabbit occurred independently in Australia and Europe from different progenitor viruses. Although this is the canonical study of the evolution of virulence, whether the genomic and phenotypic outcomes of MYXV evolution in Europe mirror those observed in Australia is unknown. We addressed this question using viruses isolated in the United Kingdom early in the MYXV epizootic (1954-1955) and between 2008-2013. The later UK viruses fell into three distinct lineages indicative of a long period of separation and independent evolution...
March 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28240799/revascularization-of-atherosclerotic-renal-artery-stenosis-for-chronic-heart-failure-versus-acute-pulmonary-oedema
#10
Darren Green, James P Ritchie, Constantina Chrysochou, Philip A Kalra
AIM: To determine whether the apparent benefit of revascularization of renal artery stenosis for "flash" pulmonary oedema extends to heart failure patients without a history of prior acute pulmonary oedema. METHODS: A prospective study of patients with renal artery stenosis and heart failure at a single centre between 1(st) January 1995 and 31(st) December 2010. Patients were divided into those with and without previous acute pulmonary oedema / decompensation. Survival analysis compared revascularization versus medical therapy in each group using Cox regression adjusted for age, eGFR, blood pressure, and co-morbidities...
February 27, 2017: Nephrology
https://www.readbyqxmd.com/read/28205623/preventive-effects-of-carnosine-on-lipopolysaccharide-induced-lung-injury
#11
Ken-Ichiro Tanaka, Toshifumi Sugizaki, Yuki Kanda, Fumiya Tamura, Tomomi Niino, Masahiro Kawahara
Acute respiratory distress syndrome (ARDS) is a potentially devastating form of acute lung injury, which involves neutrophilic inflammation and pulmonary cell death. Reactive oxygen species (ROS) play important roles in ARDS development. New compounds for inhibiting the onset and progression of ARDS are required. Carnosine (β-alanyl-L-histidine) is a small di-peptide with numerous activities, including antioxidant effects, metal chelation, proton buffering capacity and the inhibition of protein carbonylation and glycoxidation...
February 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28202366/modulation-of-the-trpv4-ion-channel-as-a-therapeutic-target-for-disease
#12
REVIEW
Megan S Grace, Sara J Bonvini, Maria G Belvisi, Peter McIntyre
Transient Receptor Potential Vanilloid 4 (TRPV4) is a broadly expressed, polymodally gated ion channel that plays an important role in many physiological and pathophysiological processes. TRPV4 knockout mice and several synthetic pharmacological compounds that selectively target TRPV4 are now available, which has allowed detailed investigation in to the therapeutic potential of this ion channel. Results from animal studies suggest that TRPV4 antagonism has therapeutic potential in oedema, pain, gastrointestinal disorders, and lung diseases such as cough, bronchoconstriction, pulmonary hypertension, and acute lung injury...
February 12, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28155296/paraquat-intoxication-and-associated-pathological-findings-in-three-dogs-in-south-africa
#13
June H Williams, Zandri Whitehead, Erna Van Wilpe
Paraquat is a bipyridylium non-selective contact herbicide commonly used worldwide. When ingestion occurs by humans and animals either accidentally, intentionally or maliciously, paraquat selectively accumulates in the lungs resulting in the production of oxygen-free radicals, causing membrane damage and cell death. Intoxicated subjects typically show progressive and fatal pulmonary haemorrhage, collapse and oedema. In individuals surviving the acute phase, pulmonary fibrosis develops. Gastrointestinal-, renal- and central nervous system clinical signs may also occur...
November 9, 2016: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/28151385/transfusion-associated-circulatory-overload-in-adult-medical-emergency-patients-with-perspectives-on-early-warning-practice-a-single-centre-clinical-study
#14
Fanny Gosmann, Astrid Nørgaard, Maj-Britt Rasmussen, Charlotte Rahbek, Jens Seeberg, Tom Møller
BACKGROUND: Transfusion-associated circulatory overload is characterised by acute respiratory distress, tachycardia, increased blood pressure, acute pulmonary oedema and/or evidence of positive fluid balance occurring within 6 hours after transfusion. Transfusion-associated circulatory overload is a serious, underreported reaction, which makes this iatrogenic condition difficult to prevent. We present an audit of patients admitted to a medical emergency unit, aiming to investigate: (i) the incidence of transfusion-associated circulatory overload; and (ii) whether cases were reported to the haemovigilance system...
January 26, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28143879/acute-high-altitude-sickness
#15
Andrew M Luks, Erik R Swenson, Peter Bärtsch
At any point 1-5 days following ascent to altitudes ≥2500 m, individuals are at risk of developing one of three forms of acute altitude illness: acute mountain sickness, a syndrome of nonspecific symptoms including headache, lassitude, dizziness and nausea; high-altitude cerebral oedema, a potentially fatal illness characterised by ataxia, decreased consciousness and characteristic changes on magnetic resonance imaging; and high-altitude pulmonary oedema, a noncardiogenic form of pulmonary oedema resulting from excessive hypoxic pulmonary vasoconstriction which can be fatal if not recognised and treated promptly...
January 2017: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/28094583/signal-detection-activity-on-eudravigilance-data-analysis-of-the-procedure-and-findings-from-an-italian-regional-centre-for-pharmacovigilance
#16
Luca Monaco, Mauro Melis, Chiara Biagi, Monia Donati, Ester Sapigni, Alberto Vaccheri, Domenico Motola
BACKGROUND: In July 2012 a new European legislation (Directive 2010/84/EU and Regulation No. 1235/2010) regarding pharmacovigilance has become effective. It has boosted the activity of Signal Detection through a monthly analysis of potential safety signals on EudraVigilance (EV). Our aim is to describe the procedure of signal detection on EV data and to present results obtained by the our pharmacovigilance centre. METHOD: Data are extracted from EV database, which collects suspected Adverse Drug Reactions (ADRs) of medicinal products in Europe...
March 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28061831/acute-kidney-injury-as-an-independent-risk-factor-for-unplanned-90-day-hospital-readmissions
#17
Simon Sawhney, Angharad Marks, Nick Fluck, David J McLernon, Gordon J Prescott, Corri Black
BACKGROUND: Reducing readmissions is an international priority in healthcare. Acute kidney injury (AKI) is common, serious and also a global concern. This analysis evaluates AKI as a candidate risk factor for unplanned readmissions and determines the reasons for readmissions. METHODS: GLOMMS-II is a large population cohort from one health authority in Scotland, combining hospital episode data and complete serial biochemistry results through data-linkage. 16453 people (2623 with AKI and 13830 without AKI) from GLOMMS-II who survived an index hospital admission in 2003 were used to identify the causes of and predict readmissions...
January 6, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/27932428/delayed-ventricular-septal-rupture-complicating-anterior-wall-myocardial-infarction
#18
Rajdip Dulai, Aye Hline, Mahvesh Rana Javaid, Javed Akhtar
A 59-year-old woman was admitted to our hospital with acute pulmonary oedema and cardiogenic shock 35 days after anterior ST elevation myocardial infarction. She developed a new loud pan systolic murmur. Echocardiography revealed a ventricular septal rupture with a significant left to right shunt. She was immediately transferred to the local cardiothoracic unit where she underwent a successful ventricular septal defect (VSD) repair. Ventricular septal rupture often presents within the first 24 hours of acute myocardial infarction and is rare thereafter...
December 8, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27921210/tight-junctions-in-pulmonary-epithelia-during-lung-inflammation
#19
REVIEW
Oliver H Wittekindt
Inflammatory lung diseases like asthma bronchiale, chronic obstructive pulmonary disease and allergic airway inflammation are widespread public diseases that constitute an enormous burden to the health systems. Mainly classified as inflammatory diseases, the treatment focuses on strategies interfering with local inflammatory responses by the immune system. Inflammatory lung diseases predispose patients to severe lung failures like alveolar oedema, respiratory distress syndrome and acute lung injury. These life-threatening syndromes are caused by increased permeability of the alveolar and airway epithelium and exudate formation...
January 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/27903671/sports-related-lung-injury-during-breath-hold-diving
#20
REVIEW
Tanja Mijacika, Zeljko Dujic
The number of people practising recreational breath-hold diving is constantly growing, thereby increasing the need for knowledge of the acute and chronic effects such a sport could have on the health of participants. Breath-hold diving is potentially dangerous, mainly because of associated extreme environmental factors such as increased hydrostatic pressure, hypoxia, hypercapnia, hypothermia and strenuous exercise.In this article we focus on the effects of breath-hold diving on pulmonary function. Respiratory symptoms have been reported in almost 25% of breath-hold divers after repetitive diving sessions...
December 2016: European Respiratory Review: An Official Journal of the European Respiratory Society
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