Yu Jing Liang, Yu Yao Wang, Shi Song Rong, Zhen Ji Chen, Shu Ying Chen, Jenson A Tham, Poemen P Chan, Jason C Yam, Janey L Wiggs, Chi Pui Pang, Clement C Tham, Li Jia Chen
IMPORTANCE: Effects of genetic variants on primary angle-closure disease remained uncertain. OBJECTIVE: To systematically review the associations of common single-nucleotide variants (SNVs) and rare coding variants with primary angle-closure disease, its subtypes (including primary angle-closure glaucoma, primary angle-closure suspect, and primary angle-closure) and progression. DATA SOURCES: Eligible studies from PubMed, Embase, and Web of Science were retrieved up to April 3, 2023...
March 28, 2024: JAMA Ophthalmology