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Angle closure glaucoma

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https://www.readbyqxmd.com/read/27915382/high-intensity-focused-ultrasound-treatment-in-patients-with-refractory-glaucoma
#1
Giuseppe Giannaccare, A Vagge, C Gizzi, A Bagnis, S Sebastiani, C Del Noce, M Fresina, C E Traverso, E C Campos
PURPOSE: To assess the safety and efficacy of ultrasound coagulation of the ciliary body in refractory glaucoma. METHODS: This prospective multicenter interventional study was conducted in two Italian university-affiliated glaucoma centers: St. Orsola-Malpighi Teaching Hospital (Bologna, Italy) and University Eye Clinic of Genoa (Genoa, Italy). The main inclusion criterion was the diagnosis of glaucoma with a baseline intraocular pressure (IOP) ≥ 21 mmHg while on maximum topical and systemic medical hypotensive treatment...
December 3, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27905331/prevalent-practice-patterns-in-glaucoma-poll-of-indian-ophthalmologists-at-a-national-conference
#2
Nikhil Shreeram Choudhari, Vanita Pathak-Ray, Sushmita Kaushik, Prateep Vyas, Ronnie George
PURPOSE: The aim of this study is to explore and compare the prevailing practice patterns in the diagnosis and management of glaucoma among subspecialists and general ophthalmologists in India. MATERIALS AND METHODS: This is an interactive audience response system (ARS) based poll of ophthalmologists attending the annual conference of the Glaucoma Society of India in 2013. RESULTS: The information was obtained from 379 ophthalmologists (146 glaucoma specialists, 54 nonglaucoma subspecialists, and 179 general ophthalmologists)...
October 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27899368/diagnostic-ability-of-peripapillary-vessel-density-measurements-of-optical-coherence-tomography-angiography-in-primary-open-angle-and-angle-closure-glaucoma
#3
Harsha L Rao, Sujatha V Kadambi, Robert N Weinreb, Narendra K Puttaiah, Zia S Pradhan, Dhanaraj A S Rao, Rajesh S Kumar, Carroll A B Webers, Rohit Shetty
AIMS: To evaluate the diagnostic ability of peripapillary vessel density measurements on optical coherence tomography angiography (OCTA) in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG), and to compare these with peripapillary retinal nerve fibre layer (RNFL) thickness measurements. METHODS: In a cross-sectional study, 48 eyes of 33 healthy control subjects, 63 eyes of 39 patients with POAG and 49 eyes of 32 patients with PACG underwent OCTA (RTVue-XR, Optovue, Fremont, California, USA) and RNFL imaging with spectral domain OCT...
November 29, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27898467/an-update-on-therapeutic-modalities-for-the-prevention-of-angle-closure-glaucoma
#4
Behzad Amoozgar, Sasan Moghimi, Ying Han, Shan C Lin
PURPOSE OF REVIEW: Angle closure glaucoma is a prominent burden for the worldwide health system. Because this disorder is commonly asymptomatic, and can lead to irreversible blindness, the proper screening and early management of this disease can be critical. The definitions of angle closure and consequently its treatment guidelines have been dynamically modified and updated in the past decades. Surgical and laser techniques have been adapted to address the different mechanisms involved in the manifestation of the disease and properly prevent its progression in different stages...
November 25, 2016: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/27898466/genetics-and-genetic-testing-for-glaucoma
#5
Matthew A Miller, John H Fingert, Daniel I Bettis
PURPOSE OF REVIEW: In recent decades, investigators have identified numerous genes and genetic factors that cause or contribute risk for glaucoma. These findings have increased our understanding of disease mechanisms, provided us with new diagnostic tools, and may allow for development of improved therapies for glaucoma. However, genetic testing is most useful when it is reserved for appropriate patients. The purpose of this article is to review key points and recent developments regarding the genetics and genetic testing for glaucoma and to provide recommendations for when genetic testing may be warranted...
November 25, 2016: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/27874246/predicting-the-intereye-asymmetry-in-functional-and-structural-damage-in-glaucoma-using-automated-pupillography
#6
Harsha L Rao, Sujatha V Kadambi, Srilakshmi Dasari, Hemanth B Reddy, Meena Palakurthy, Mohammed Riyazuddin, Narendra K Puttaiah, Zia S Pradhan, Dhanaraj A S Rao, Rohit Shetty
PURPOSE: To predict the intereye asymmetry in functional (mean deviation, MD on visual field, VF) and structural (retinal nerve fibre layer, RNFL and ganglion cell complex, GCC thickness on spectral domain optical coherence tomography, SDOCT) measurements in glaucoma using the automated pupillography parameters. METHODS: Fifty-nine subjects with a diagnosis of either glaucoma or glaucoma suspect underwent automated pupillography along with VF and SDOCT examinations...
November 22, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27857491/spectrum-of-angle-closure-uveal-effusion-syndrome-and-nanophthalmos
#7
Eric Areiter, Matthew Neale, Sandra M Johnson
: Nanophthalmos, uveal effusion syndrome, and acute angle closure glaucoma (ACG) can present as a continuum in a patient, as is described here. This patient's angle closure was thought to be caused by idiopathic uveal effusion syndrome, and while there are no generally accepted diagnosis criteria for nanophthalmos, our patient fulfilled the criteria as defined by Wu.(10) To prevent development of further angle closure, the decision was made to do cataract extraction as opposed to medical management...
September 2016: Journal of Current Glaucoma Practice
https://www.readbyqxmd.com/read/27849312/oct-angiography-of-the-peripapillary-retina-in-primary-open-angle-glaucoma
#8
Eun Ji Lee, Kyoung Min Lee, Seung Hyen Lee, Tae-Woo Kim
Purpose: The purpose of this study was to investigate the topographic relationship between the decreased parapapillary retinal microvasculature as assessed by optical coherence tomography angiography (OCTA) and retinal nerve fiber layer (RNFL) defect in eyes with primary open-angle glaucoma (POAG) and a localized RNFL defect. Methods: The peripapillary retinal circulation was evaluated using the OCTA centered on the optic nerve head in 98 POAG eyes having a localized RNFL defect and 45 healthy control eyes...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27830199/qualitative-evaluation-of-anterior-segment-in-angle-closure-disease-using-anterior-segment-optical-coherence-tomography
#9
Sasan Moghimi, Rebecca Chen, Nikoo Hamzeh, Nassim Khatibi, Shan C Lin
PURPOSE: To evaluate different mechanisms of primary angle closure (PAC) and to quantify anterior chamber (AC) parameters in different subtypes of angle closure disease using anterior segment optical coherence tomography (AS-OCT). METHODS: In this prospective study, 115 eyes of 115 patients with angle closure disease were included and categorized into three groups: 1) fellow eyes of acute angle closure (AAC; 40 eyes); 2) primary angle closure glaucoma (PACG; 39 eyes); and 3) primary angle closure suspect (PACS; 36 eyes)...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27830195/anterior-segment-optical-coherence-tomography-in-subtypes-of-angle-closure-glaucoma
#10
EDITORIAL
Kouros Nouri-Mahdavi
No abstract text is available yet for this article.
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27828849/preliminary-results-of-co2-laser-assisted-sclerectomy-surgery-class-in-the-treatment-of-advanced-glaucoma-in-a-chinese-population
#11
Doris W F Yick, Jacky W Y Lee, Susanna Tsang, Barry Y M Yeung, Can Y F Yuen
To evaluate the efficacy and safety of CO2 laser-assisted sclerectomy surgery (CLASS) in Chinese patients with advanced glaucoma.Patients with advanced glaucoma who were candidates for glaucoma filtration surgery were included. The intraocular pressure (IOP) and number of antiglaucoma medications were documented before surgery and at all postoperative clinic visits. All intra- and postoperative complications were documented. The primary outcome measures were the changes in IOP and medication use before and after the procedure as well as complications from the procedure...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27824919/primary-angle-closure-and-sequence-variants-within-microrna-binding-sites-of-genes-involved-in-eye-development
#12
Haihong Shi, Junfang Zhang, Rongrong Zhu, Nan Hu, Hong Lu, Mei Yang, Bai Qin, Jian Shi, Huaijin Guan
PURPOSE: The formation of primary angle closure (PAC) and primary angle closure glaucoma (PACG) is regulated by a tissue remodeling pathway that plays a critical role in eye development. MicroRNAs (miRNAs) are powerful gene expression regulators and may exert their effects on tissue remodeling genes. This study investigated the associations between gene variants (single-nucleotide polymorphism, SNP) in miRNA binding sites in the 3'-UTR region of genes involved in eye development and PAC...
2016: PloS One
https://www.readbyqxmd.com/read/27790769/prevalence-types-and-awareness-of-glaucoma-in-a-multi-ethnic-population-in-rural-china-the-yunnan-minority-eye-study
#13
Chen-Wei Pan, Chun-Hua Zhao, Min-Bin Yu, Qing Cun, Qin Chen, Wei Shen, Jun Li, Jian-Gang Xu, Yuansheng Yuan, Hua Zhong
PURPOSE: To determine the prevalence, types and awareness of glaucoma in a rural community in China and to examine possible ethnic variations. METHODS: The Yunnan Minority Eye Study was a multi-ethnic community-based eye survey using random cluster sampling strategies. 2133 Bai, 2205 Han and 2208 Yi Chinese aged 50 years or older participated in this study. Glaucoma including primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG) and secondary glaucoma was defined based on the International Society of Geographical and Epidemiological Ophthalmology criteria...
November 2016: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/27788183/angle-closure-scoring-system-acss-a-scoring-system-for-stratification-of-angle-closure-disease
#14
Aparna Rao, Debananda Padhy, Sarada Sarangi, Gopinath Das
PURPOSE: To evaluate the angle closure scoring system (ACSS) for stratifying primary angle course disease. METHODS: This observational cross sectional institutional study included patients with primary open angle glaucoma suspects (n = 21) and primary angle closure disease (primary angle closure, PAC, n = 63 and primary angle course glaucoma, PACG, n = 58 (defined by International society of Geographical and Epidemiological Ophthalmology, ISGEO). Two independent examiners blinded to clinical details, graded good quality pre-laser goniophotographs of the patients incorporating quadrants of peripheral anterior synechieae (PAS), non-visibility of posterior trabecular meshwork (PTM) and blotchy pigments (ranging from 1-4 quadrants), iris configuration, angle recess (sum of above depicting ACSSg) and lens thickness/axial length ratio (LT/AL), cup disc ratio and baseline intraocular pressure (IOP) to give total score (ACSSt)...
2016: PloS One
https://www.readbyqxmd.com/read/27758063/course-of-serum-autoantibodies-in-patients-after-acute-angle-closure-glaucoma-attack
#15
Katrin Lorenz, Sabine Beck, Munir M Keilani, Joanna Wasielica-Poslednik, Norbert Pfeiffer, Franz H Grus
BACKGROUND: The aim of our current investigation was to analyze the autoantibody -reactivities of patients after acute angle closure glaucoma (AACG) by means of a protein microarray approach to identify intraocular pressure (IOP)-dependent antibodies. METHODS: Collected sera from different study time points (AACG n = 6, 0, 2, 4 and 12 weeks) and control group (CTRL n = 11, 0 and 12 weeks) were analyzed. Protein-microarrays were incubated with sera and occurring immunoreactivities were visualized with fluorescence labeled anti-human-IgG antibodies...
October 18, 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27728509/topiramate-induced-angle-closure-glaucoma-in-a-case-of-chronic-migraine
#16
Y S Sirohi, V A Arun, Yatharth Dixit
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27726963/changes-in-anterior-segment-morphology-and-predictors-of-angle-widening-after-laser-iridotomy-in-south-indian-eyes
#17
Nazlee Zebardast, Srinivasan Kavitha, Palaniswamy Krishnamurthy, David S Friedman, Monisha E Nongpiur, Tin Aung, Harry A Quigley, Pradeep Y Ramulu, Rengaraj Venkatesh
PURPOSE: To compare anterior segment optical coherence tomography (ASOCT) angle morphology before and after laser peripheral iridotomy (LPI) in a cohort of South Indian subjects with primary angle-closure suspect (PACS) or primary angle-closure/primary angle-closure glaucoma (PAC/PACG) and to examine baseline parameters associated with angle widening. DESIGN: Prospective observational study. PARTICIPANTS: A total of 244 subjects aged ≥30 years with PACS or PAC/PACG in at least 1 eye...
October 7, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27707497/effectiveness-of-early-lens-extraction-for-the-treatment-of-primary-angle-closure-glaucoma-eagle-a-randomised-controlled-trial
#18
COMMENT
Augusto Azuara-Blanco, Jennifer Burr, Craig Ramsay, David Cooper, Paul J Foster, David S Friedman, Graham Scotland, Mehdi Javanbakht, Claire Cochrane, John Norrie
BACKGROUND: Primary angle-closure glaucoma is a leading cause of irreversible blindness worldwide. In early-stage disease, intraocular pressure is raised without visual loss. Because the crystalline lens has a major mechanistic role, lens extraction might be a useful initial treatment. METHODS: From Jan 8, 2009, to Dec 28, 2011, we enrolled patients from 30 hospital eye services in five countries. Randomisation was done by a web-based application. Patients were assigned to undergo clear-lens extraction or receive standard care with laser peripheral iridotomy and topical medical treatment...
October 1, 2016: Lancet
https://www.readbyqxmd.com/read/27698750/effects-of-phacoemulsification-and-intraocular-lens-implantation-combined-with-ciliarotomy-in-the-treatment-of-angle-closure-glaucoma-with-cataract
#19
Bo Li, Feng-Yun Wang, Tai-Liang Lv, Yu Zhu
The aim of the present study was to examine the effects of phacoemulsification and intraocular lens implantation combined with ciliarotomy in the treatment of angle-closure glaucoma with cataract in the elderly. A total of 68 patients were consecutively selected and divided into the control group with 33 cases (48 eyes) and the observation group with 35 cases (53 eyes). Cataract surgery combined with trabeculectomy was performed on the patients in the control group and phacoemulsification cataract extraction combined with ciliarotomy was performed on the subjects in the observation group, to compare postoperative effects and complications...
October 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27690232/patient-reported-vision-related-quality-of-life-differences-between-primary-angle-closure-glaucoma-and-primary-open-angle-glaucoma
#20
Hui-Chen Cheng, Chao-Yu Guo, Yu-Jing Chen, Mei-Ju Chen, Yu-Chieh Ko, Nicole Huang, Catherine Jui-Ling Liu
PURPOSE: To investigate the different impacts on patient-reported vision-related quality of life (pVRQOL) outcomes in patients with primary angle-closure glaucoma(PACG) and primary open-angle glaucoma(POAG). METHODS: Prospective cross-sectional study. PACG and POAG patients who had a best-corrected visual acuity(BCVA) in the better eye equal to or better than 20/60, intraocular pressure controlled at or below 25 mmHg and reliable visual field test were invited to participate...
2016: PloS One
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