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Angle closure glaucoma

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https://www.readbyqxmd.com/read/28644235/chandelier-illumination-for-descemet-membrane-endothelial-keratoplasty
#1
Toshiki Shimizu, Takahiko Hayashi, Kentaro Yuda, Ayako Tsuchiya, Itaru Oyakawa, Nobuhisa Mizuki, Naoko Kato
PURPOSE: To describe a simple technique that uses posterior chandelier illumination during Descemet membrane endothelial keratoplasty in cases of severe bullous keratopathy (BK). METHODS: Five eyes of 4 patients with advanced BK undergoing Descemet membrane endothelial keratoplasty were retrospectively analyzed. The pupil of the host eye was not treated with mydriatic or miotic agents. The chandelier illuminator was inserted transconjunctivally into the vitreous cavity from the pars plana...
June 21, 2017: Cornea
https://www.readbyqxmd.com/read/28640115/management-of-neovascular-glaucoma-with-intravitreal-ranibizumab-panretinal-photocoagulation-and-subsequent-5-fluorouracil-augmented-trabeculectomy-a-case-report
#2
Xinyue Zhao, Zhi Wang, Xiaobo Yang
RATIONALE: Neovascular glaucoma (NVG) is one of the most refractory types of glaucoma caused by high ischemic retinal disorders, resulting in severe visual loss. Intravitreal injections of ranibizumab have been reported to have anatomical and functional success in treating NVG. PATIENT CONCERNS-DIAGNOSES-INTERVENTIONS: We report a case with neovascular glaucoma due to central retinal vein occlusion who received combination therapy with intravitreal ranibizumab (IVR) injection, panretinal photocoagulation (PRP) and subsequent 5-fluorouracil (5-FU) augmented trabeculectomy...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28617521/regular-versus-releasable-sutures-in-surgery-for-primary-congenital-glaucoma
#3
Nader H Bayoumi
PURPOSE: To compare releasable and regular sutures in combined angle and filtering surgery for primary congenital glaucoma. METHODS: A prospective study was conducted on 39 eyes (26 right eyes) of 39 children (20 boys; 19 girls) who had primary congenital glaucoma treated with combined trabeculotomy-trabeculectomy with mitomycin C and scleral flap closure with regular or releasable sutures. Follow-up was 24 months. Success rates (defined as an intraocular pressure [IOP] < 16 mm Hg without hypotony-related complications and/or lack of IOP-related progression of the disease) were studied and complications were noted...
June 15, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28607771/retrospective-study-of-vitreous-tap-technique-using-needle-aspiration-for-management-of-shallow-anterior-chamber-during-phacoemulsification
#4
Ashraf Ahmed Nossair, Wael Ahmed Ewais, Lamia Samy Ali
PURPOSE: To evaluate the technique of vitreous tap using needle aspiration for management of anterior chamber shallowness during phacoemulsification. METHODS: A retrospective study included 26 eyes of 17 patients who underwent phacoemulsification in which vitreous tap was performed using a 27-gauge needle attached to a 5 ml syringe, inserted 3.5 mm from the limbus to aspirate 0.2 ml of liquefied vitreous if a cohesive (OVD) failed to sufficiently deepen the anterior chamber...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28586796/functional-activity-of-matrix-metalloproteinases-2-and-9-in-tears-of-patients-with-glaucoma
#5
Prity Sahay, Aparna Rao, Debananda Padhy, Sarada Sarangi, Gopinath Das, Mamatha M Reddy, Rahul Modak
Purpose: To evaluate the differential expression of tear matrix metalloproteinases (MMP) 2 and 9 in of patients with various forms of glaucoma. Methods: Tear samples were collected with a Schirmer's strip from 148 eyes of 113 patients (medically naïve patients with primary open-angle [POAG] or angle closure glaucoma [PACG] and those with pseudoexfoliation syndrome [PXF] or glaucoma [PXG]). These were compared to patients undergoing cataract surgery (controls) for this cross-sectional study...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28584204/decision-making-impairments-in-primary-angle-closure-glaucoma-patients
#6
Hui Pu, Yong Wang, Qiang Wei, Hui-Juan Ma, Pan-Pan Hu, Shou-Ling Li, Hong-Bo Pang, Yang-Hua Tian, Kai Wang
BACKGROUND: Primary angle-closure glaucoma (PACG) is a common eye disease and a common cause of blindness. Inappropriate medical decisions severely affect the prognosis. This study investigated decision-making under risk in PACG patients. METHODS: Thirty patients with first acute attack of PACG before surgery and thirty healthy controls were included in the study. Decision-making under risk was evaluated with the game of dice task (GDT). The results of Eysenck Personality Questionnaire (EPQ) and GDT between PACG patients and healthy controls were compared...
June 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28579788/primary-angle-closure-glaucomas-disturb-regional-spontaneous-brain-activity-in-the-visual-pathway-an-fmri-study
#7
Wei Chen, Li Zhang, Yong-Gen Xu, Kai Zhu, Man Luo
OBJECTIVE: To explore the underlying regional brain activity deficits in the visual cortex in patients with primary angle-closure glaucoma (PACG) relative to normal controls (NCs) using regional homogeneity (ReHo) method, and its relationship with behavioral performances. PATIENTS: Twenty PACG patients (10 females, 10 males; mean age ± standard deviation [SD]: 54.42±9.46 years) and 20 age-, and sex status-matched NCs (10 females, 10 males; mean age ± SD: 53.75±9...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28577860/glaucoma
#8
REVIEW
Jost B Jonas, Tin Aung, Rupert R Bourne, Alain M Bron, Robert Ritch, Songhomitra Panda-Jonas
Glaucoma is a heterogeneous group of diseases characterised by cupping of the optic nerve head and visual-field damage. It is the most frequent cause of irreversible blindness worldwide. Progression usually stops if the intraocular pressure is lowered by 30-50% from baseline. Its worldwide age-standardised prevalence in the population aged 40 years or older is about 3·5%. Chronic forms of glaucoma are painless and symptomatic visual-field defects occur late. Early detection by ophthalmological examination is mandatory...
May 31, 2017: Lancet
https://www.readbyqxmd.com/read/28562545/sumatriptan-induced-angle-closure-glaucoma-a-case-report
#9
Cherng-Ru Hsu, Yi-Hao Chen, Ming-Cheng Tai, Da-Wen Lu
RATIONALE: Drug-induced bilateral angle-closure glaucoma is a rare event and should be treated correctly and promptly to prevent visual loss. PATIENT CONCERNS: We report a rare case of sumatriptan-induced bilateral angle-closure glaucoma in a young woman with migraine, and explore the possible mechanism. DIAGNOSES: We describe the clinical outcome of a patient with sumatriptan-induced bilateral angle-closure glaucoma. The patient presented with bilateral acute elevation of intraocular pressure (IOP) and myopic shift...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28542344/dynamic-changes-of-anterior-segment-in-patients-with-different-stages-of-primary-angle-closure-in-both-eyes-and-normal-subjects
#10
Jialiu Lin, Zhonghao Wang, Chuchen Chung, Jianan Xu, Miaomiao Dai, Jingjing Huang
PURPOSE: To compare changes in anterior segment parameters under light and dark (light-to-dark) conditions among eyes with chronic primary angle-closure glaucoma (CPACG), fellow eyes with confirmed or suspect primary angle-closure (PAC or PACS), and age-matched healthy eyes. METHODS: Consecutive patients with CPACG in one eye and PAC/PACS in the fellow eye, as well as age-matched healthy subjects were recruited. Anterior segment optical coherence tomography measurements were conducted under light and dark conditions, and anterior chamber, lens, and iris parameters compared...
2017: PloS One
https://www.readbyqxmd.com/read/28522116/a-new-approach-for-the-management-of-primary-angle-closure-glaucoma-after-eagle-trial
#11
F J Muñoz Negrete, A Azuara-Blanco
No abstract text is available yet for this article.
May 15, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28505344/genetics-of-glaucoma
#12
Janey L Wiggs, Louis R Pasquale
Genetic and genomic studies, including genome-wide association studies (GWAS) have accelerated the discovery of genes contributing to glaucoma, the leading cause of irreversible blindness world-wide. Glaucoma can occur at all ages, with Mendelian inheritance typical for rare early onset disease (before age 40) and complex inheritance evident in common adult-onset forms of disease. Recent studies have suggested possible therapeutic targets for some patients with early-onset glaucoma based on the molecular and cellular events caused by MYOC, OPTN and TBK1 mutations...
May 15, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28499992/segmentation-and-quantification-for-angle-closure-glaucoma-assessment-in-anterior-segment-oct
#13
Huazhu Fu, Yanwu Xu, Stephen Lin, Xiaoqin Zhang, Damon Wing Kee Wong, Jiang Liu, Alejandro Frangi, Mani Baskaran, Tin Aung
Angle-closure glaucoma is a major cause of irreversible visual impairment and can be identified by measuring the anterior chamber angle (ACA) of the eye. The ACA can be viewed clearly through Anterior Segment Optical Coherence Tomography (AS-OCT), but the imaging characteristics and the shapes and locations of major ocular structures can vary significantly among different AS-OCT modalities, thus complicating image analysis. To address this problem, we propose a datadriven approach for automatic AS-OCT structure segmentation, measurement and screening...
May 10, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28494566/-the-prevalence-of-blindness-caused-by-primary-angle-closure-glaucoma-in-middle-aged-chinese-population-a-systematic-review-and-meta-analysis
#14
M L Liu, Y X Wang
Objective: To evaluate the rate of blindness caused by primary angle closure glaucoma (PACG) in Chinese population of more than 40 years old, and to explore the effectiveness of a prevention and treatment system on PACG. Methods: We searched the databases of Pubmed, ScienceDirect, Springer Link, CNKI and Wanfang Data and collected all the original studies of the prevalence and blindness of angle closure glaucoma in China. The population was limited to over 40 years old. The research site was limited to the community-based, while the published time was not limited...
May 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28492910/effect-of-bevacizumab-vs-aflibercept-on-visual-acuity-among-patients-with-macular-edema-due-to-central-retinal-vein-occlusion-the-score2-randomized-clinical-trial
#15
Ingrid U Scott, Paul C VanVeldhuisen, Michael S Ip, Barbara A Blodi, Neal L Oden, Carl C Awh, Derek Y Kunimoto, Dennis M Marcus, John J Wroblewski, Jacqueline King
Importance: Studies have established the efficacy and safety of aflibercept for the treatment of macular edema due to central retinal vein occlusion. Bevacizumab is used off-label to treat this condition despite the absence of supporting data. Objective: To investigate whether bevacizumab is noninferior to aflibercept for the treatment of macular edema secondary to central retinal or hemiretinal vein occlusion. Design, Setting, and Participants: The SCORE2 randomized noninferiority clinical trial was conducted at 66 private practice or academic centers in the United States, and included 362 patients with macular edema due to central retinal or hemiretinal vein occlusion who were randomized 1:1 to receive aflibercept or bevacizumab...
May 23, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28489705/retinal-and-choroidal-vascular-occlusion-following-aqueous-misdirection-syndrome-in-a-patient-with-sickle-cell-trait
#16
Samantha Dewundara, Nariman Nassiri, Johnstone M Kim, Huseyin Kadikoy, Wendewessen Amde, Justin Tannir, Bret A Hughes, Gary W Abrams
PURPOSE: To report a patient with retinal and choroidal vascular occlusion as a presenting sign of sickle cell trait following the development of aqueous misdirection syndrome. METHODS: Retrospective chart review. RESULTS: A patient treated for bilateral chronic angle-closure glaucoma with sequential EX-PRESS glaucoma filtration device surgery developed sequential bilateral aqueous misdirection syndrome. The left eye developed retinal arterial and localized choroidal vascular occlusions subsequent to an acute elevation in intraocular pressure and possibly the use of oral acetazolamide...
May 9, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28442694/surgical-treatment-of-angle-closure-glaucoma
#17
Dawn Lim, Maria Cecilia Aquino, Paul Chew
Advances in anterior segment imaging modalities have contributed new insights towards a better understanding of the various mechanisms of angle-closure glaucoma (ACG). This development is key to good decision making when confronted with angle-closure patients needing appropriate therapy. Surgical management of ACG remains an integral part of glaucoma patient care. The distinctive anatomy of angle-closure eyes and the few objective lines of evidence to support the effectiveness of the different surgical treatment options present a challenge to glaucoma surgeons...
2017: Developments in Ophthalmology
https://www.readbyqxmd.com/read/28442692/viscocanalostomy-and-canaloplasty-ab-externo-schlemm-s-canal-surgery
#18
Matthias C Grieshaber
Ab externo Schlemm's canal (SC) surgery (e.g., viscocanalostomy and canaloplasty) is a valuable alternative to glaucoma filtration surgery. It targets the abnormally high resistance to outflow in the trabecular meshwork (TM) and reestablishes the physiologic outflow system. In viscocanalostomy, viscoelastic substance is injected to dilate SC, which in turn leads to microdisruptions of the inner wall. In canaloplasty, the additional intracanalicular stent (suture or Stegmann Canal Expander®) keeps the canal patent and enhances the circumferential flow...
2017: Developments in Ophthalmology
https://www.readbyqxmd.com/read/28442685/deep-sclerectomy
#19
Sylvain Roy, André Mermoud
Filtering surgery evolved from the classic trabeculectomy, in which penetration into the anterior chamber is a necessary step, toward nonpenetrating deep sclerectomy. The first procedure presents several serious complications, such as durable hypotony, hyphema, flat anterior chamber, choroidal detachment, endophthalmitis, and surgery-induced cataract. To avoid such drawbacks, a novel nonpenetrating technique was designed to improve the predictability of the intraocular pressure (IOP)-lowering action, while reducing the incidence of the immediate postoperative complications encountered with the penetrating method...
2017: Developments in Ophthalmology
https://www.readbyqxmd.com/read/28413868/goniosynechialysis-and-repositioning-of-intraocular-lens-in-a-case-of-secondary-angle-closure-glaucoma
#20
Masaru Fujita, Masafumi Ogata, Yasuyuki Suzuki, Tsunetomo Ichihashi, Miyuki Nagahara, Kenji Kawai
PURPOSE: Implanting intraocular lens (IOL) in proper direction is important in cataract surgery to reduce the possibility of undesirable complications. We experienced a case who underwent vitrectomy combined with cataract surgery and developed secondary angle closure glaucoma caused by IOL misdirection. Goniosynechialysis (GSL) and repositioning of IOL successfully ameliorated the high intraocular pressure (IOP). CASE REPORT: A 64-year-old male with massive vitreous hemorrhage underwent vitrectomy combined with cataract surgery...
April 20, 2017: Tokai Journal of Experimental and Clinical Medicine
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