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Angle closure glaucoma

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https://www.readbyqxmd.com/read/29130529/anterior-segment-morphology-after-laser-iridotomy-in-primary-angle-closure-suspects
#1
Tarannum Mansoori, Nagalla Balakrishna
PURPOSE: To evaluate and compare the changes in anterior segment parameters in primary angle closure suspects before and after laser peripheral iridotomy and intrasession repeatability of measurements before laser iridotomy as assessed by Scheimpflug-Placido disc topographer. METHODS: Before laser iridotomy, 56 eyes of 56 primary angle closure suspect patients underwent anterior segment analysis with the Sirius Scheimpflug-Placido disc topographer system using glaucoma analysis mode, which was repeated a week after iridotomy...
November 12, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29118839/acute-angle-closure-glaucoma-a-potential-blind-spot-in-critical-care
#2
Anna Petsas, George Chapman, Richard Stewart
We report a case of a 69-year-old gentleman who developed an acutely painful eye with loss of visual acuity whilst on the critical care unit. He was admitted three days previously with an infective exacerbation of chronic obstructive pulmonary disease requiring invasive mechanical ventilation. In addition, he received intravenous antibiotics, steroids, nebulised bronchodilators and intravenous aminophylline, together with noradrenaline for blood pressure support. On development of visual symptoms, an emergency ophthalmology review diagnosed acute angle closure glaucoma...
August 2017: J Intensive Care Soc
https://www.readbyqxmd.com/read/29104803/the-impact-of-adherence-and-instillation-proficiency-of-topical-glaucoma-medications-on-intraocular-pressure
#3
Tesfay Mehari Atey, Workineh Shibeshi, Abeba T Giorgis, Solomon Weldegebreal Asgedom
Background: The possible sequel of poorly controlled intraocular pressure (IOP) includes treatment failure, unnecessary medication use, and economic burden on patients with glaucoma. Objective: To assess the impact of adherence and instillation technique on IOP control. Methods: A cross-sectional study was conducted on 359 glaucoma patients in Menelik II Hospital from June 1 to July 31, 2015. After conducting a Q-Q analysis, multiple binary logistic analyses, linear regression analyses, and two-tailed paired t-test were conducted to compare IOP in the baseline versus current measurements...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29104631/ocular-pulse-amplitude-in-different-types-of-glaucoma-using-dynamic-contour-tonometry-diagnosis-and-follow-up-of-glaucoma
#4
Lingyan Cheng, Yuzhi Ding, Xuanchu Duan, Zhifeng Wu
The aim of the present study was to compare the ocular pulse amplitude (OPA) in patients with different types of glaucoma using dynamic contour tonometry (DCT), to evaluate ocular and systemic factors associated with the OPA and to verify whether OPA measured by DCT is an independent predictor for glaucoma diagnosis. A total of 217 eyes of 217 participants in the following five groups were included in this cross-sectional study: Chronic angle closure glaucoma (CACG), primary open angle glaucoma, normal tension glaucoma (NTG), suspected open angle glaucoma (SOAG) and normal control (NC)...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29102986/association-between-coagulation-function-and-patients-with-primary-angle-closure-glaucoma-a-5-year-retrospective-case-control-study
#5
Shengjie Li, Yanting Gao, Mingxi Shao, Binghua Tang, Wenjun Cao, Xinghuai Sun
OBJECTIVE: To evaluate the association between coagulation function and patients with primary angle closure glaucoma (PACG). DESIGN: A retrospective, hospital-based, case-control study. SETTING: Shanghai, China. PARTICIPANTS: A total of 1778 subjects were recruited from the Eye & ENT Hospital of Fudan University from January 2010 to December 2015, including patients with PACG (male=296; female=569) and control subjects (male=290; female=623)...
November 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/29097742/associated-factors-of-acute-primary-angle-closure-glaucoma-in-a-sub-group-of-chinese-people-comparison-between-attack-eyes-and-normal-controls
#6
Lifang Liu, Xinyu Liu, Chukai Huang, Geng Wang, Di Ma, Wanqi Zhang, Ce Zheng, Mingzhi Zhang
Acute primary angle closure glaucoma (APACG) is an ophthalmic emergency that may lead to irreversible blindness. Although efforts were made to control intraocular pressure, disease progression still existed. Anterior segment optical coherence tomography (AS OCT) may provide a new insight into mechanism of APACG. In order to seek out associated factors by AS OCT, We compared anterior segment parameters between 74 APACG and 48 normal eyes. Analysis of variance, principle component analysis and logistic regression were used...
November 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29096997/comparison-of-new-visual-disturbances-after-superior-versus-nasal-temporal-laser-peripheral-iridotomy-a-prospective-randomized-trial
#7
Kavitha Srinivasan, Nazlee Zebardast, Palaniswamy Krishnamurthy, Mohideen Abdul Kader, Ganesh V Raman, Sharmila Rajendrababu, Rengaraj Venkatesh, Pradeep Y Ramulu
PURPOSE: To determine whether laser peripheral iridotomy (LPI) location affects postoperative dysphotopsia symptoms. DESIGN: Multicenter, randomized, prospective, single-masked trial. PARTICIPANTS: Five hundred fifty-nine South Indian patients 30 years of age or older diagnosed as primary angle-closure suspects (PACSs) or with primary angle closure (PAC) or primary angle-closure glaucoma (PACG) in both eyes. METHODS: Patients were randomized to either bilateral superior or bilateral nasal/temporal LPI...
October 30, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29095997/aqueous-humour-flow-in-the-posterior-chamber-of-the-eye-and-its-modifications-due-to-pupillary-block-and-iridotomy
#8
M Dvoriashyna, R Repetto, M R Romano, J H Tweedy
The anterior chamber (AC) and posterior chamber (PC) of the eye are connected through the pupil and are filled with aqueous humour. The aqueous flows from the posterior to the AC at an approximately constant rate, and the intraocular pressure is governed by this rate and the resistance to aqueous outflow. In some patients the iris and lens come into contact, leading to pressure build-up in the PC, peripheral axial shallowing of the AC and, possibly, to angle-closure glaucoma. This can lead to blindness, which may be prevented by surgically creating an iridotomy, that is a hole through the iris to facilitate the flow from the posterior to the AC...
October 30, 2017: Mathematical Medicine and Biology: a Journal of the IMA
https://www.readbyqxmd.com/read/29094301/vertical-implantable-collamer-lens-icl-rotation-for-the-management-of-high-vault-due-to-lens-oversizing
#9
Francesco Matarazzo, Alexander Clifford Day, Luis Fernandez-Vega Cueto, Vincenzo Maurino
PURPOSE: To describe the good outcome of implantable collamer lens (ICL) rotation to reduce post-operative vault. METHODS: Retrospective analysis of case report. A 43-year-old woman had V4c EVO + myopic non-toric ICL implantation and post-operatively she presented with anisocoria and high vault. She underwent surgery to rotate the ICL 90 degrees to a vertical orientation. RESULTS: We achieved a reduction in the vault from 1020 to 486 μm after vertical ICL rotation...
November 1, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29090056/oseltamivir-tamiflu-induced-bilateral-ciliochoroidal-effusion-and-angle-closure-glaucoma-what-type-of-idiosyncratic-reaction
#10
Shahin Yazdani, Hamed Esfandiari, Sare Safi, Alireza Fatemi
PURPOSE: To report a case of bilateral acute angle closure glaucoma after one dose of oseltamivir 75 mg. CASE REPORT: A 37-year-old man with a history of influenza developed high intraocular pressure and uniformly shallow anterior chamber in both eyes, 5 hours after the first dose of oseltamivir 75 mg. The condition was managed successfully with topical cycloplegic and systemic/topical antiglaucoma medications. CONCLUSION: Since a presumed idiosyncratic reaction developed right after the first dose of the medication, it challenges the common concept of adaptive immune system involvement in this type of reaction in medication-related ciliochoroidal effusion...
October 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29082039/laser-peripheral-iridotomy-versus-trabeculectomy-as-an-initial-treatment-for-primary-angle-closure-glaucoma
#11
Yan Yun Chen, Su Jie Fan, Yuan Bo Liang, Shi Song Rong, Hai Lin Meng, Xing Wang, Ravi Thomas, Ning Li Wang
PURPOSE: To compare laser peripheral iridotomy (LPI) with trabeculectomy as an initial treatment for primary angle-closure glaucoma (PACG) with peripheral anterior synechiae (PAS) ≥ 6 clock hours. METHODS: Patients were drawn from two randomized controlled trials. 38 eyes of 38 patients (PAS ≥ 6 clock hours) were treated with LPI (group 1) while 111 eyes of 111 PACG patients (PAS ≥ 6 clock hours) underwent primary trabeculectomy (group 2). All patients underwent a comprehensive ophthalmic examination at baseline and at postoperative visits and were followed up for a minimum of one year...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29081648/resident-performed-laser-peripheral-iridotomy-in-primary-angle-closure-primary-angle-closure-suspects-and-primary-angle-closure-glaucoma
#12
Jason P Kam, Emily M Zepeda, Leona Ding, Joanne C Wen
PURPOSE: To investigate the power use and complication frequency of resident-performed laser peripheral iridotomy (LPI). METHODS: A retrospective analysis of 196 eyes from 103 patients who underwent neodymium: yttrium-aluminum-garnet laser iridotomy performed by resident physicians from January 1, 2010 through April 30, 2015 at a university-based county hospital was done. All patients were treated for primary angle closure, primary angle closure suspects, and primary angle closure glaucoma...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29063980/bilateral-acute-angle-closure-glaucoma-and-myopic-shift-by-topiramate-induced-ciliochoroidal-effusion-case-report-and-literature-review
#13
Yu-Wen Lan, Jui-Wen Hsieh
PURPOSE: To report two cases of ciliochoroidal effusion after the usage of topiramate. CASES: Two middle-aged women experienced sudden onset of acute glaucoma and acquired myopia after taking topiramate. Ultrasound biomicroscopy demonstrated bilateral ciliochoroidal effusion and angle closure. The A-scan ultrasonography revealed shallow anterior chamber and thick lens. After the treatment and drug withdrawal, intraocular pressure, refractive status and angle anatomy returned to normal and there was resolution of ciliochoroidal effusion...
October 24, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29062779/understanding-practice-patterns-of-glaucoma-sub-specialists-in-india
#14
Nikhil S Choudhari, Vanita Pathak-Ray, Sushmita Kaushik, Prateep Vyas, Ronnie George
AIM: To obtain information on the prevailing practice patterns of glaucoma specialists in India. METHODS: Glaucoma specialists attending the Annual Conference of the Glaucoma Society of India (GSI) were surveyed. This survey, conducted in 2013, was based on an interactive audience response system. RESULTS: The information was obtained from 146 glaucoma specialists. Approximately half (n=83; 57%) had ≥10y of experience in managing glaucoma and were in institutional practice (n=74, 51%)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29044061/long-term-scanning-laser-ophthalmoscopy-and-perimetry-in-different-severities-of-primary-open-and-chronic-angle-closure-glaucoma-eyes
#15
Ramanjit Sihota, Aparna Rao, Geetha Srinivasan, Viney Gupta, Ajay Sharma, Tanuj Dada, M Kalaiwani
PURPOSE: To determine rate of change over time on scanning laser ophthalmoscopy, HRT, compared to perimetry, and to determine incidence, parametric changes, and risk factors for progression in primary open angle glaucoma (POAG) and chronic primary angle closure angle glaucoma (CPACG) eyes. METHODS: Prospective clinical study of 116 POAG eyes and 129 CPACG eyes of different severities of glaucoma. Standard automated perimetry and optic nerve head topography were studied at baseline and thereafter every 6 months...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29035183/atypical-presentation-of-acute-angle-closure-glaucoma-in-maroteaux-lamy-mucopolysaccharidosis-with-patent-prophylactic-laser-peripheral-iridotomy-a-case-report
#16
Malini Veerappan, Garrick Chak, Christine Shieh, Pratap Challa
INTRODUCTION: Maroteaux-Lamy syndrome (MLS) is a rare progressive condition characterized by inflammation and scarring of multiple organs. Ocular complications caused by anterior segment abnormalities commonly cause visual impairment in MLS. Angle-closure glaucoma is one such complication, but there are limited data on presentation, workup, and management of this condition. CASE PRESENTATION: This case report describes an atypical presentation of acute angle-closure glaucoma in a patient with MLS despite a prior prophylactic laser peripheral iridotomy-which would typically prevent an acute angle-closure attack-that was patent and intact at the time of angle closure...
2017: Permanente Journal
https://www.readbyqxmd.com/read/29016860/primary-angle-closure-glaucoma-pacg-susceptibility-gene-plekha7-encodes-a-novel-rac1-cdc42-gap-that-modulates-cell-migration-and-blood-aqueous-barrier-function
#17
Mei-Chin Lee, William Shei, Anita S Chan, Boon-Tin Chua, Shuang-Ru Goh, Yaan-Fun Chong, Maryam H Hilmy, Monisha E Nongpiur, Mani Baskaran, Chiea-Chuen Khor, Tin Aung, Walter Hunziker, Eranga N Vithana
PLEKHA7, a gene recently associated with primary angle closure glaucoma (PACG), encodes an apical junctional protein expressed in components of the blood aqueous barrier (BAB). We found that PLEKHA7 is down-regulated in lens epithelial cells and in iris tissue of PACG patients. PLEKHA7 expression also correlated with the C risk allele of the sentinel SNP rs11024102 with the risk allele carrier groups having significantly reduced PLEKHA7 levels compared to non-risk allele carriers. Silencing of PLEKHA7 in human immortalized non-pigmented ciliary epithelium (h-iNPCE) and primary trabecular meshwork cells, which are intimately linked to BAB and aqueous humor outflow respectively, affected actin cytoskeleton organization...
October 15, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28991617/goniotomy-with-a-single-use-dual-blade-short-term-results
#18
Michael D Greenwood, Leonard K Seibold, Nathan M Radcliffe, Syril K Dorairaj, Ahmad A Aref, Jesús Jimenez Román, Gabriel S Lazcano-Gomez, Jason K Darlington, Suhail Abdullah, Mark C Jasek, Khaled A Bahjri, John P Berdahl
PURPOSE: To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of a single-use dual blade (Kahook) in patients with mild to end-stage glaucoma. SETTING: International multicenter ophthalmic care centers. DESIGN: Prospective interventional case series. METHODS: Consecutive patients with glaucoma who had phacoemulsification plus goniotomy with the single-use dual blade were enrolled in this study. Each center collected deidentified clinical data, including preoperative and postoperative IOP, medication use, adverse events, and whether additional surgery was required during a 6-month follow-up...
September 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28989288/a-family-of-early-english-oculists-1600-1751-with-a-reappraisal-of-john-thomas-woolhouse-1664-1733-1734
#19
REVIEW
Christopher T Leffler, Stephen G Schwartz
INTRODUCTION: John Thomas Woolhouse (1666-1733/1734), who practiced in Paris, was part of a family with 5 generations of English oculists. Some historians have derided him as a "charlatan" and have criticized him for adhering to the old notion that a cataract was a membrane anterior to the lens. METHODS: We reviewed treatises and digital records related to Woolhouse and his family and the handwritten notes of his 1721 lecture series at the Royal Society of Medicine...
2017: Ophthalmology and Eye Diseases
https://www.readbyqxmd.com/read/28986594/plateau-iris-distribution-across-anterior-segment-optical-coherence-tomography-defined-subgroups-of-subjects-with-primary-angle-closure-glaucoma
#20
Sushma Verma, Monisha E Nongpiur, Hnin H Oo, Eray Atalay, David Goh, Tina T Wong, Shamira A Perera, Tin Aung
Purpose: We previously identified three distinct subgroups of patients with primary angle closure glaucoma (PACG) based on anterior segment optical coherence tomography (ASOCT) imaging. Group 1 was characterized by a large iris area with deepest anterior chambers, group 2 by a large lens vault (LV) and shallow anterior chamber depth (ACD), and group 3 displayed intermediate values across iris area, LV, and ACD. The purpose of the present study was to determine the distribution of plateau iris in these subgroups using ultrasound biomicroscopy (UBM) features...
October 1, 2017: Investigative Ophthalmology & Visual Science
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