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https://www.readbyqxmd.com/read/28637345/-he-wouldn-t-turn-me-loose
#1
Rick J Scheidt
No abstract text is available yet for this article.
June 16, 2017: Gerontologist
https://www.readbyqxmd.com/read/28636902/-riddle-me-this-substrate-channeling-solves-the-paradigms-of-camp-dependent-activation-of-pka
#2
César A Ramírez-Sarmiento
No abstract text is available yet for this article.
June 20, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28635483/student-life-imposter-syndrome
#3
Mandy Day-Calder
I will never forget the first time I stepped onto a ward as a nursing student in my freshly ironed new uniform. Everything was going well. This was it, I was living my dream. And then an older woman called out for a nurse, looked at me, and I froze. I wasn't a 'real' nurse, so what on earth was I to do?
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28635478/let-s-celebrate-the-feel-good-factor
#4
Jane Bates
I am ignored. Disregarded. A non-person. Part of the furniture. But I don't mind. In fact, it gives me a warm glow.
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28633629/prevalence-of-and-risk-factors-for-severe-cognitive-and-sleep-symptoms-in-me-cfs-and-ms
#5
Vageesh Jain, Amit Arunkumar, Caroline Kingdon, Eliana Lacerda, Luis Nacul
BACKGROUND: There are considerable phenotypic and neuroimmune overlaps between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis (MS). While the precise aetiologies of both MS and ME/CFS are unclear, evidence suggests that deterioration in cognitive function is widely prevalent in patients with either condition. Little is known about differing risk factors or exposures, which may lead to severe cognitive or sleep symptoms. This study aims to gauge the extent of cognitive and sleep symptoms in ME/CFS and MS patients participating in the UK ME/CFS Biobank and identify the characteristics of those experiencing severe symptoms...
June 20, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28633177/give-me-what-s-in-your-heart
#6
Nidhi Lal
No abstract text is available yet for this article.
June 2017: Family Medicine
https://www.readbyqxmd.com/read/28632244/pain-management-in-the-middle-east-building-capacity-with-global-partners
#7
Jeannine M Brant, Susie Newton, Martha A Maurer
The Middle East (ME) is an economically diverse region that includes countries in Central Asia and Northern Africa. Regardless, cancer is a major health concern in the ME, and pain management is an essential component of cancer care across the disease trajectory. This column will provide background on opioid use for pain management in the ME and highlight the collaborative work of the Middle Eastern Cancer Consortium, Omani Cancer Association, and the Oncology Nursing Society to increase pain assessment and management capacity in the ME...
July 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28631141/cell-labeling-with-magneto-endosymbionts-and-the-dissection-of-the-subcellular-location-fate-and-host-cell-interactions
#8
Kayla R Lee, Abdul Wakeel, Papia Chakraborty, Chandler S Foote, Lauren Kajiura, Joyce C Barrozo, Andrea C Chan, Alexey V Bazarov, Ryan Spitler, Peter M Kutny, Jim M Denegre, Rob A Taft, Joachim Seemann, Bradley W Rice, Christopher H Contag, Brian K Rutt, Caleb B Bell
PURPOSE: The purposes of this study are to characterize magneto-endosymbiont (ME) labeling of mammalian cells and to discern the subcellular fate of these living contrast agents. MEs are novel magnetic resonance imaging (MRI) contrast agents that are being used for cell tracking studies. Understanding the fate of MEs in host cells is valuable for designing in vivo cell tracking experiments. PROCEDURES: The ME's surface epitopes, contrast-producing paramagnetic magnetosomal iron, and genome were studied using immunocytochemistry (ICC), Fe and MRI contrast measurements, and quantitative polymerase chain reaction (qPCR), respectively...
June 19, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28630465/changes-in-pore-structure-of-coal-caused-by-coal-to-gas-bioconversion
#9
Rui Zhang, Shimin Liu, Jitendra Bahadur, Derek Elsworth, Yi Wang, Guanglong Hu, Yanna Liang
Microbial enhanced coalbed methane (ME-CBM) recovery is critically examined as a viable technology for natural gas recovery from coalbed methane (CBM) reservoirs. Since the majority of gas-in-place (GIP) is stored as an adsorbed phase in fine pores of coal matrix, the nano-pore structure directly influences gas storage and transport properties. Only limited studies have quantified the alteration of the nano-pore structure due to ME-CBM treatment. This study examines the evolution of the pore structure using a combination of small angle X-ray scattering (SAXS), low-pressure N2 and CO2 adsorption (LPGA) and high-pressure methane adsorption methods...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28629978/dual-roles-of-tpgs-based-microemulsion-for-tacrolimus-enhancing-the-percutaneous-delivery-and-anti-psoriatic-efficacy
#10
Tao Wan, Jingtong Pan, Yueming Long, Kaiyue Yu, Yixuan Wang, Wenhui Pan, Wenyi Ruan, Mengyao Qin, Chuanbin Wu, Yuehong Xu
In this study, we demonstrate for the first time the dual roles of Tocopheryl Polyethylene Glycol 1000 Succinate (TPGS) based microemulsion (ME) for tacrolimus (TAC) to enhance TAC percutaneous delivery and anti-psoriatic efficacy. The ME formulation was developed and optimized based on pseudo-ternary phase diagrams combined with in vitro permeation. The result of Fourier transform infrared spectroscopy (FTIR) demonstrated that TAC was completely solubilized in the TPGS-ME. In vitro permeation studies showed that TPGS-ME enhanced TAC permeation through and into the skin, and the enhanced deposition of TAC in the normal or psoriatic skin was further confirmed in vivo...
June 16, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28629438/an-output-evaluation-of-a-health-research-foundation-s-enhanced-grant-review-process-for-new-investigators
#11
Gregory W Hammond, Mê-Linh Lê, Tannis Novotny, Stephanie P B Caligiuri, Grant N Pierce, John Wade
BACKGROUND: We assessed the ability of the Manitoba Medical Service Foundation (MMSF, a small not-for-profit foundation affiliated with Manitoba Blue Cross) to determine the best candidates for selection to receive research funding support among new researchers applying to the Research Operating Grants Programme (ROGP). METHODS: Using bibliometric and grants funding analyses, we retrospectively compared indices of academic outputs from five cohorts of MMSF-funded and not MMSF-funded applicants to the annual MMSF ROGP over 2008 to 2012, from 1 to 5 years after having received evaluation decisions from the MMSF enhanced grant review process...
June 19, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28628898/-talking-about-child-sexual-abuse-would-have-helped-me-young-people-who-sexually-abused-reflect-on-preventing-harmful-sexual-behavior
#12
Gemma McKibbin, Cathy Humphreys, Bridget Hamilton
Harmful sexual behavior carried out by children and young people accounts for about half of all child sexual abuse perpetration. The aim of this study was to draw on the insights of young people who had been sexually abusive to enhance the current prevention agenda. The study involved semi-structured interviews with 14 young people and six treatment-providing workers. Sampling was purposive and the young people had previously completed a treatment program for harmful sexual behaviour in Victoria, Australia...
June 16, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28628208/carbocyclic-c-c-bond-formation-intramolecular-radical-ring-closure-to-yield-diastereomerically-pure-7-s-me-or-7-r-me-carba-lna-nucleotide-analogs
#13
Oleksandr Plashkevych, Ram Shankar Upadhayaya, Jyoti Chattopadhyaya
In light of the impressive gene-silencing properties of carba-LNA modified oligo DNA and RNA, both in antisense RNA and siRNA approaches, which have been confirmed as proof-of-concept for biochemical applications in post-transcriptional gene silencing, we envision the true potential of carba-LNA modifications to be revealed soon. Herein we provide detailed protocols for synthesis of carba-LNA-A, -G, -(5-Me) C, and -T nucleosides on a medium/large scale (gram scale), as well as important guidelines for incorporation of these modified carba-LNAs into DNA or RNA oligonucleotides...
June 19, 2017: Current Protocols in Nucleic Acid Chemistry
https://www.readbyqxmd.com/read/28628165/practical-in-situ-generation-of-phosphinite-ligands-for-palladium-catalyzed-carbonylation-of-hetero-aryl-bromides-forming-esters
#14
Lin Wang, Helfried Neumann, Anke Spannenberg, Matthias Beller
An effective method for alkoxycarbonylation of (hetero)aryl bromides is developed in the presence of in situ-generated phosphinite ligands (t)Bu2POR (R = (n)Bu, (n)Pr, Et or Me). For this purpose commercially available (t)Bu2PCl was used as the pre-ligand in the presence of different alcohols. For the first time cross coupling reactions with two alcohols - one generating the ligand, the other used as substrate - were developed. Through this method, ligand optimization can be performed in a more efficient manner and the desired products could be obtained with good yields and selectivity...
June 19, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28627056/feed-intake-patterns-of-sport-ponies-and-warmblood-horses-following-iso-energetic-intake-of-pelleted-fibre-rich-mixed-feed-muesli-feed-and-semicrushed-oat-grains
#15
M Bochnia, M Boesel, L Bahrenthien, M Wensch-Dorendorf, A Zeyner
The aim of the study was to compare diverse feed intake patterns in sport ponies and warmblood-type horses after feeding iso-energetic amounts of three different concentrates: a pelleted fibre-rich mixed feed (PF), a muesli feed (MF) and semicrushed oat grains (OG). Four sport ponies and six warmblood-type horses received the concentrates and meadow hay according to maintenance (0.52 MJ metabolizable energy (ME) kg body weight (BW)(0.75) /day). Both breeds were allocated at random to three groups and received once daily for 8 days either OG (1 g starch/kg BW/meal) or iso-energetic quantities of PF and MF according to a crossover design...
June 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28627053/recovery-of-insulin-sensitivity-and-optimal-body-composition-after-rapid-weight-loss-in-obese-dogs-fed-a-high-protein-medium-carbohydrate-diet
#16
A André, I Leriche, G Chaix, C Thorin, M Burger, P Nguyen
This study investigated the effects of an experimental high-protein medium-carbohydrate diet (protein level, 46% metabolizable energy, ME). First, postprandial plasma glucose and insulin kinetics were determined in steady-state overweight/obese Beagle dogs (28%-41% excess body weight) for an experimental high-protein medium-carbohydrate diet (protein level, 46% ME) and a commercial high-carbohydrate medium-protein diet (protein level, 24%ME) in obese dogs. Secondly, all the dogs were included in a weight loss programme...
June 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28627042/deciding-about-nursing-home-care-in-dementia-a-conjoint-analysis-of-how-older-people-balance-competing-goals
#17
Alison Fahey, Dearbhail Ní Chaoimh, Grainne R Mulkerrin, Eamon C Mulkerrin, Shaun T O'Keeffe
AIM: "Don't put me in a home" is a common preference of older people, but so too is "I don't want to be a burden on my family." These and other goals often conflict with each other when people have worsening dementia and the issue of possible nursing home admission arises. METHODS: Community-dwelling older hospital patients were asked to imagine that they lived alone, had dementia and were experiencing increasing practical difficulties, and were presented with 11 possible "outcome packages...
June 18, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28626439/attentive-observation-is-essential-for-the-misattribution-of-agency-to-self-performance
#18
Shiho Kashihara, Noriaki Kanayama, Makoto Miyatani, Takashi Nakao
Recent studies have repeatedly demonstrated a false memory phenomenon in which people falsely remember having performed an action by oneself when in fact they have only observed the action by another person. We investigated the attentional effect to the action itself on the observation inflation. Fifty-four participants first performed and read actions (Phase 1); then, they observed the action video that showed another's actions (Phase 2), some of which they had not performed in Phase 1. In the Phase 2, they were required to focus on either the actor's performance (i...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28625910/a-high-fat-diet-enhances-the-sensitivity-of-chick-adipose-tissue-to-the-effects-of-centrally-injected-neuropeptide-y-on-gene-expression-of-adipogenesis-associated-factors
#19
Guoqing Wang, Carli A Williams, Betty R McConn, Mark A Cline, Elizabeth R Gilbert
The purpose of this study was to determine how dietary macronutrient composition and exogenous neuropeptide Y (NPY) affect mRNA abundance of factors associated with lipid metabolism in chick adipose tissue. Chicks were fed one of three isocaloric (3000kcal metabolizable energy (ME)/kg) diets after hatch: high carbohydrate (HC; control), high fat (HF; 30% of ME from soybean oil) or high protein (HP; 25% crude protein). On day 4 post-hatch, vehicle or 0.2nmol of NPY was injected intracerebroventricularly and abdominal and subcutaneous fat depots collected 1h later...
June 15, 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/28625350/multi-electrode-bioelectrochemical-system-for-the-treatment-of-high-total-dissolved-solids-bearing-chemical-based-wastewater
#20
G Velvizhi, S Venkata Mohan
Multi-electrode bioelectrochemical treatment system (ME-BET; membrane less) consisting of six electrode assemblies (E1-E6) was designed and fabricated for the treatment of complex chemical based wastewater with high salt concentration. The performance was compared with single electrode assembly BET reactor (SE-BET). Enhanced TDS and COD removal was observed in ME-BET (32%; 56%) compared to SE-BET (15%; 23%) as a result of in situ bio-potential from multi-electrodes through the oxidation of organic substrate in the wastewater...
May 10, 2017: Bioresource Technology
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