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https://www.readbyqxmd.com/read/28110379/-they-are-talking-about-me-but-not-with-me-a-focus-group-study-to-explore-the-patient-perspective-on-interprofessional-team-meetings-in-primary-care
#1
Jerôme Jean Jacques van Dongen, Maarten de Wit, Hester Wilhelmina Henrica Smeets, Esther Stoffers, Marloes Amantia van Bokhoven, Ramon Daniëls
BACKGROUND: The number of people with multiple chronic conditions receiving primary care services is growing. To deal with their increasingly complex health care demands, professionals from different disciplines need to collaborate. Interprofessional team (IPT) meetings are becoming more popular. Several studies describe important factors related to conducting IPT meetings, mostly from a professional perspective. However, in the light of patient-centeredness, it is valuable to also explore the patients' perspective...
January 21, 2017: Patient
https://www.readbyqxmd.com/read/28109602/strategies-to-gain-body-condition-score-in-pasture-based-dairy-cows-during-late-lactation-and-the-far-off-nonlactating-period-and-their-interaction-with-close-up-dry-matter-intake
#2
J R Roche, A Heiser, M D Mitchell, M A Crookenden, C G Walker, J K Kay, M Vailati Riboni, J J Loor, S Meier
In pasture-based systems, cows are generally thinner at the end of lactation than cows fed total mixed rations and, as a result, over-feeding of metabolizable energy (ME) during the far-off nonlactating period is a standard management policy to achieve optimum calving body condition score (BCS). An alternative would be to manage cows to gain BCS through late lactation, such that cows ended lactation close to optimum calving BCS and maintenance of BCS through to calving. We sought to quantify the effect of moderate or excessive ME intakes during the far-off nonlactating period in cows that had been managed to gain or maintain BCS through late lactation and whether the far-off management strategy interacted with close-up level of feeding...
January 18, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28109205/haloterrigena-mahii-sp-nov-an-extreme-halophilic-archaeon-from-the-solar-saltern
#3
Jiun-Yan Ding, Sheng-Chung Chen, Mei-Chin Lai, Tsai-Ling Liao
A pleomorphic, gas vesicle containing, halophilic archaeon, designated strain H13T, was isolated from the solar saltern of the Western Salt Co., Chula Vista, California, USA. Cells of strain H13T were non-motile, rod-shaped and 3-10 μm in length. The optimum growth conditions were 3.5-5.0 M NaCl, 45-55 oC, and pH range of 6.5-8.2. The major polar lipids were C20C20 and C20C25 derivatives of phosphatidylglycerol (PG), phosphatidylglycerol phosphate methyl ester (PGP-Me) and disulfated diglycosyl diether-1 (S2-DGD-1)...
January 21, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28108222/diquat-induced-cellular-pyridine-nucleotide-redox-changes-and-alteration-of-metabolic-enzyme-activities-in-colonic-carcinoma-cells
#4
Magdalena L Circu, Ronald E Maloney, Tak Yee Aw
Previously we have shown that the redox cycler menadione (MQ) induced cellular pyridine nucleotide redox imbalance that was linked to a decrease in aerobic glycolysis and perturbation of the mitochondrial respiratory activity due to the redox cycling of the compound; these processes were potentiated by low glucose. In this study, we investigated how colonic epithelial cells maintained pyridine nucleotide (NAD(+)/NADH and NADP(+)/NADPH) redox homeostasis upon acute metabolic variation and exposure to the redox cycling diquat (DQ)...
January 17, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28107620/chemical-interaction-of-protein-cysteine-residues-with-reactive-metabolites-of-methyleugenol
#5
Yukun Feng, Hui Wang, Qian Wang, Wenlin Huang, Ying Peng, Jiang Zheng
Methyleugenol (ME), an alkenylbenzene compound, is a natural ingredient of several herbs and is used as flavoring agent in foodstuffs and fragrance in cosmetics. The hepatotoxicity, cytotoxicity, and carcinogenesis of ME have been well documented, and metabolic activation has been suggested to involve in ME-induced toxicities. The objective of this study was to identify chemical identity of interactions of protein with reactive metabolites of ME. Modification of cysteine residues of protein was observed in microsomal incubations and mice after exposure to ME...
January 20, 2017: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/28107330/tell-me-about-you-experiences-teach-a-nurse-the-importance-of-listening%C3%A2
#6
Julie Beck
Unexpected cardiac issues at an early age inspired me to return to school to pursue a career in nursing. While in school, a close relationship with a family member facing a terminal cancer diagnosis gave me insight into the importance of listening as a tool for keeping patients safe and delivering the most appropriate care. These insights have shaped my career as I moved from student to RN to oncology nurse practitioner.
February 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28106855/pharmacomodulation-of-the-antimalarial-plasmodione-synthesis-of-biaryl-and-n-arylalkylamine-analogues-antimalarial-activities-and-physicochemical-properties
#7
Karène Urgin, Mouhamad Jida, Katharina Ehrhardt, Tobias Müller, Michael Lanzer, Louis Maes, Mourad Elhabiri, Elisabeth Davioud-Charvet
With the aim of increasing the structural diversity on the early antimalarial drug plasmodione, an efficient and versatile procedure to prepare a series of biaryl- and N-arylalkylamines as plasmodione analogues is described. Using the naturally occurring and commercially available menadione as starting material, a 2-step sequence using a Kochi-Anderson reaction and subsequent Pd-catalyzed Suzuki-Miyaura coupling was developed to prepare three representative biphenyl derivatives in good yields for antimalarial evaluation...
January 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28106392/anti-osteoporotic-activity-of-harpagoside-by-upregulation-of-the-bmp2-and-wnt-signaling-pathways-in-osteoblasts-and-suppression-of-differentiation-in-osteoclasts
#8
Hwa-Jin Chung, Won Kyung Kim, Jedo Oh, Me-Riong Kim, Joon-Shik Shin, Jinho Lee, In-Hyuk Ha, Sang Kook Lee
Harpagoside (1) is an iridoid glycoside isolated from the radix of Harpagophytum procumbens var. sublobatum, commonly called Devil's claw. The anti-osteoporotic effect of 1 was investigated in both in vitro cell cultures and in vivo using an ovariectomized (OVX) mouse model. Compound 1 induced bone formation by stimulating osteoblast proliferation, alkaline phosphatase activity, and mineralization in osteoblastic MC3T3-E1 cells. Treatment with 1 increased the mRNA and protein expression of bone formation biomarkers through regulation of the BMP2 and Wnt signaling pathway in MC3T3-E1 cells...
January 20, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28106249/targeted-forcing-improves-quality-nutritional-and-health-value-of-sweet-cherry-fruit
#9
Verena Overbeck, Michaela Schmitz, Michael Blanke
BACKGROUND: Trade and consumers alike require premium quality cherries with high nutritional and health values preferably of local origin. While early fruit imports cannot supply such fruit, a new technology of forcing cherry emerged for an early local supply by covering the crop in spring. In the apparent scarcity of data on the resulting fruit quality, fruit characteristics of forced cherries were compared with those without cover RESULTS: Size and weight of forced cherry fruit were successfully increased by 6-14%...
January 20, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28106245/a-randomized-controlled-trial-of-mediterranean-diet-and-metformin-to-prevent-age-related-diseases-in-people-with-metabolic-syndrome
#10
Patrizia Pasanisi, Giuliana Gargano, Maria Gaetana Di Mauro, Mauro Cortellini, Alice Casagrande, Anna Villarini, Eleonora Bruno, Eliana Roveda, Gabriella Saibene, Elisabetta Venturelli, Franco Berrino
PURPOSE: Age-related non-communicable chronic diseases (ArCDs) are the leading cause of mortality. The major metabolic risk factor for their development is the metabolic syndrome (MetS), defined as a clustering of risk factors of metabolic origin such as abdominal obesity, high blood pressure, dyslipidemia and high fasting glycemia. There is increasing observational and experimental evidence that improving diet and the use of metformin (a calorie-restriction mimetic drug) may modify the risk of developing MetS and ArCD...
January 20, 2017: Tumori
https://www.readbyqxmd.com/read/28105100/clinical-significance-of-leukocyte-associated-immunoglobulin-like-receptor-1-expression-in-human-cervical-cancer
#11
Yue Wang, Xueshan Zhang, Fang Miao, Yanning Cao, Jiangnan Xue, Qizhi Cao, Xiaoshu Zhang
Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is broadly expressed on the majority of immune cells; however, the biological role of LAIR in solid tumors has yet to be elucidated. In the present study, using immunohistochemical staining analysis, the expression of LAIR-1 in human cervical cancer (HCC) and nontumor-adjacent tissue specimens was determined, and the results indicated that the expression of LAIR-1 in HCC tissue was higher compared with that in noncancerous tissue. The χ(2) test was used to analyze the correlation between the expression of LAIR-1 in tumor tissues with clinicopathological parameters...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28104625/natural-course-of-chronic-fatigue-syndrome-myalgic-encephalomyelitis-in-adolescents
#12
Tom Norris, Simon M Collin, Kate Tilling, Roberto Nuevo, Stephen A Stansfeld, Jonathan Ac Sterne, Jon Heron, Esther Crawley
OBJECTIVE: Little is known about persistence of or recovery from chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in adolescents. Previous studies have small sample sizes, short follow-up or have focused on fatigue rather than CFS/ME or, equivalently, chronic fatigue, which is disabling. This work aimed to describe the epidemiology and natural course of CFS/ME in adolescents aged 13-18 years. DESIGN: Longitudinal follow-up of adolescents enrolled in the Avon Longitudinal Study of Parents and Children...
January 19, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28103549/cardiac-image-reconstruction-via-non-linear-motion-correction-based-on-partial-angle-reconstructed-images
#13
Seungeon Kim, Yongjin Chang, Jong Beom Ra
Even though the X-ray CT scan is considered suitable for fast imaging, motion-artifact-free cardiac imaging is still an important issue because the gantry rotation speed is not fast enough compared with the heart motion. To obtain a heart image with less motion artifacts, a motion estimation (ME) and motion compensation (MC) approach is usually adopted. In this paper, we propose a ME/MC algorithm that can estimate a non-linear heart motion model from a sinogram with a rotation angle of less than 360°. In this algorithm, we first assume the heart motion to be non-rigid but linear, and thereby estimate an initial 4D motion vector field (MVF) during a half rotation by using conjugate partial angle reconstructed images, as in our previous ME/MC algorithm...
January 17, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28103527/distinct-cortico-striatal-connections-with-subthalamic-nucleus-underlie-facets-of-compulsivity
#14
Laurel S Morris, Kwangyeol Baek, Valerie Voon
The capacity to flexibly respond to contextual changes is crucial to adapting to a dynamic environment. Compulsivity, or behavioural inflexibility, consists of heterogeneous subtypes with overlapping yet discrete neural substrates. The subthalamic nucleus (STN) mediates the switch from automatic to controlled processing to slow, break or stop behaviour when necessary. Rodent STN lesions or inactivation are linked with perseveration or repetitive, compulsive responding. However, there are few studies examining the role of latent STN-centric neural networks and compulsive behaviour in healthy individuals...
December 29, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28101542/revisiting-secondary-interactions-in-neighboring-group-participation-exemplified-by-reactivity-changes-of-iminylium-intermediates
#15
Yingtang Ning, Tomoya Fukuda, Hirotaka Ikeda, Yuko Otani, Masatoshi Kawahata, Kentaro Yamaguchi, Tomohiko Ohwada
Neighboring group participation is defined as the action of a substituent to stabilize a transition state or an intermediate by forming a bond or a partial bond with the reaction center. In addition to the primary interaction with the nearest neighboring group, secondary interactions involving another neighboring group(s) could also occur in principle. Here, we revisit this issue by examining the influence of secondary interactions on the stability and reactivity of the putative iminylium cation intermediates, formed by N-O bond cleavage of 1-tetralone oxime systems...
January 19, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28101372/lessons-i-have-learned-from-my-patients-everyday-life-with-primary-orthostatic-tremor
#16
Marie Vidailhet, Emmanuel Roze, Lucie Maugest, Cécile Gallea
BACKGROUND: Primary orthostatic tremor is a rare disorder that is still under-diagnosed or misdiagnosed. Motor symptoms are fairly characteristics but the real impact on the patient's every day life and quality of life is under-estimated. The "how my patients taught me" format describes the impact on the patients' every day life with their own words, which is rarely done. CASE PRESENTATION: A 46 year old lady was diagnosed primary orthostatic tremor (POT) based on the cardinal symptoms: feelings of instability, leg tremor and fear of falling in the standing position, improvement with walking and disappearance while sitting, frequency of Tremor in the 13-18Hz range, normal neurological examination...
2017: Journal of Clinical Movement Disorders
https://www.readbyqxmd.com/read/28100440/it-s-about-me-patients-experiences-of-patient-participation-in-the-web-behavior-change-program-for-activity-in-combination-with-multimodal-pain-rehabilitation
#17
Catharina Nordin, Peter Michaelson, Margareta K Eriksson, Gunvor Gard
BACKGROUND: Patients' participation in their health care is recognized as a key component in high-quality health care. Persons with persistent pain are recommended treatments with a cognitive approach from a biopsychosocial explanation of pain, in which a patient's active participation in their rehabilitation is in focus. Web-based interventions for pain management have the potential to increase patient participation by enabling persons to play a more active role in rehabilitation. However, little is known about patients' experiences of patient participation in Web-based interventions in clinical practice...
January 18, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28099673/accelerated-second-degree-bachelor-of-science-in-nursing-graduates-transition-to-professional-practice
#18
Cheryl L Brandt, Melissa R Boellaard, Kaitlyn M Wilberding
: HOW TO OBTAIN CONTACT HOURS BY READING THIS ISSUE Instructions: 1.2 contact hours will be awarded by Villanova University College of Nursing upon successful completion of this activity. A contact hour is a unit of measurement that denotes 60 minutes of an organized learning activity. This is a learner-based activity. Villanova University College of Nursing does not require submission of your answers to the quiz. A contact hour certificate will be awarded after you register, pay the registration fee, and complete the evaluation form online at http://goo...
January 1, 2017: Journal of Continuing Education in Nursing
https://www.readbyqxmd.com/read/28099022/molecular-weight-dependence-of-interdiffusion-and-adhesion-of-polymers-at-short-contact-times
#19
Robert Gurney, Anastase Henry, Regis Schach, Anke Lindner, Costantino Creton
The self-adhesion and subsequent debonding of thin layers of three linear and monodisperse random copolymers of styrene-butadiene (SBR) with molecular weights varying between 30 and 75 times the average molecular weight between entanglements Me was investigated using a carefully controlled tack adhesion testing device in conjunction with a fast camera setup over a range of contact times tc (10 ms to 10 s) much shorter in comparison to the terminal relaxation times of the polymers. The evolution of the stress-strain curves and debonding mechanisms with increasing contact time was examined, and the work required to debond the layers was found to be strongly dependent on molecular weight at long contact times, but not at short contact times...
January 18, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28098504/effects-of-culturally-adaptive-walking-intervention-on-cardiovascular-disease-risks-for-middle-aged-korean-chinese-female-migrant-workers
#20
Hyeonkyeong Lee, Sunghye Cho, JoEllen Wilbur, Jung Hee Kim, Chang-Gi Park, Young-Me Lee, Haryong Lee
The purpose was to examine the effects of a standard treatment (ST) walking program compared to a ST walking program enhanced (Enhanced Treatment, ET) on cardiovascular health outcomes among Korean-Chinese female migrant workers in Korea. A quasi-experimental sequential design was used. A total of 132 Korean-Chinese women without contraindications to physical activity participated in the study. Both ST and ET groups had monthly goal settings and the ET group received text messages to encourage walking adherence and acculturation...
January 18, 2017: Archives of Environmental & Occupational Health
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