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https://www.readbyqxmd.com/read/28551144/multiresidue-method-for-identification-and-quantification-of-avermectins-benzimidazoles-and-nitroimidazoles-residues-in-bovine-muscle-tissue-by-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry-uhplc-ms-ms-using-a-quechers-approach
#1
Guilherme Resende da Silva, Josefa Abucater Lima, Leonardo Francisco de Souza, Flávio Alves Santos, Mary Ane Gonçalves Lana, Débora Cristina Sampaio de Assis, Silvana de Vasconcelos Cançado
A quantitative and confirmatory multiresidue method for determining the presence of avermectins, benzimidazoles and nitroimidazoles in bovine muscle tissue by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) was developed, optimized and validated, using a QuEChERS extraction. The evaluated performance parameters were linearity, selectivity, matrix effect, decision limits (CCα), detection capability (CCβ), limits of detection (LOD), limits of quantification (LOQ), accuracy, precision and robustness...
August 15, 2017: Talanta
https://www.readbyqxmd.com/read/28547843/characterization-of-protonated-model-disaccharides-from-tandem-mass-spectrometry-and-chemical-dynamics-simulations
#2
Estefania Rossich-Molina, Ane Eizaguirre, Violette Haldys, Dominique Urban, Gilles Doisneau, Yann Bourdreux, Jean-Marie Beau, Jean-Yves Salpin, Riccardo Spezia
In the present work the fragmentation mechanisms of prototypical disaccharides have been studied by coupling tandem mass spectrometry (MS) with collisional chemical dynamics simulations. These last calculations were performed by explicitly considering the collisions between the protonated sugar and the neutral target gas, leading to an ensemble of trajectories for each system, from which it was possible to obtain reaction products and mechanisms without pre-imposing them. The -aminoethyl and aminopropyl derivatives of cellobiose, maltose and gentiobiose were studied in order to see the differences in both the stereochemistry and the location of the glycosidic linkage...
May 26, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28546822/commercial-essential-oils-as-potential-antimicrobials-to-treat-skin-diseases
#3
REVIEW
Ané Orchard, Sandy van Vuuren
Essential oils are one of the most notorious natural products used for medical purposes. Combined with their popular use in dermatology, their availability, and the development of antimicrobial resistance, commercial essential oils are often an option for therapy. At least 90 essential oils can be identified as being recommended for dermatological use, with at least 1500 combinations. This review explores the fundamental knowledge available on the antimicrobial properties against pathogens responsible for dermatological infections and compares the scientific evidence to what is recommended for use in common layman's literature...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28546569/starting-embryonic-transcription-for-the-first-time
#4
Ane Iturbide, Maria-Elena Torres-Padilla
Three studies highlight DUX proteins as key transcription factors regulating embryonic genome activation in early mammalian development.
May 26, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28546280/absolute-values-of-lung-function-explain-the-sex-difference-in-breathlessness-in-the-general-population
#5
Magnus Ekström, Linus Schiöler, Rune Grønseth, Ane Johannessen, Cecilie Svanes, Benedicte Leynaert, Deborah Jarvis, Thorarinn Gislason, Pascal Demoly, Nicole Probst-Hensch, Isabelle Pin, Angelo G Corsico, Bertil Forsberg, Joachim Heinrich, Dennis Nowak, Chantal Raherison-Semjen, Shyamali C Dharmage, Giulia Trucco, Isabel Urrutia, Jesús Martinez-Moratalla Rovira, José Luis Sánchez-Ramos, Christer Janson, Kjell Torén
Activity-related breathlessness is twice as common among females as males in the general population and is associated with adverse health outcomes. We tested whether this sex difference is explained by the lower absolute forced expiratory volume in 1 s (FEV1) or forced vital capacity (FVC) in females.This was a cross-sectional analysis of 3250 subjects (51% female) aged 38-67 years across 13 countries in the population-based third European Community Respiratory Health Survey. Activity-related breathlessness was measured using the modified Medical Research Council (mMRC) scale...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28545738/-fluoride-intake-through-consumption-of-water-from-municipal-network-in-the-inma-gipuzkoa-cohort
#6
Ana Jiménez-Zabala, Loreto Santa-Marina, Mónica Otazua, Mikel Ayerdi, Ane Galarza, Mara Gallastegi, Enrique Ulibarrena, Amaia Molinuevo, Asier Anabitarte, Jesús Ibarluzea
OBJECTIVE: To estimate fluoride intake through consumption of water from the municipal network in pregnant women and their children from the INMA-Gipuzkoa cohort and to compare these intakes with recommended levels. In Euskadi (Spain), fluoridation of drinking water is compulsory in water supplies for more than 30,000 inhabitants. METHOD: 575 pregnant women (recruitment, 2006-2008) and 424 4-year-old children (follow-up, 2010-2012) have been included. Fluoride levels in drinking water were obtained from the water consumption information system of the Basque Country (EKUIS)...
May 22, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28542646/analysis-of-risk-factors-for-infant-mortality-in-the-1992-3-and-2002-3-birth-cohorts-in-rural-guinea-bissau
#7
Stine Byberg, Marie D Østergaard, Amabelia Rodrigues, Cesario Martins, Christine S Benn, Peter Aaby, Ane B Fisker
INTRODUCTION: Though still high, the infant mortality rate in Guinea-Bissau has declined. We aimed to identify risk factors including vaccination coverage, for infant mortality in the rural population of Guinea-Bissau and assess whether these risk factors changed from 1992-3 to 2002-3. METHODS: The Bandim Health Project (BHP) continuously surveys children in rural Guinea-Bissau. We investigated the association between maternal and infant factors (especially DTP and measles coverage) and infant mortality...
2017: PloS One
https://www.readbyqxmd.com/read/28538816/antioxidant-effect-of-quinoline-derivatives-containing-or-not-selenium-relationship-with-antinociceptive-action-quinolines-are-antioxidant-and-antinociceptive
#8
Ethel A Wilhelm, Ana Teresinha Ferreira, Mikaela P Pinz, Angélica S Dos Reis, Ane G Vogt, Andre L Stein, Gilson Zeni, Cristiane Luchese
The present study investigated the antioxidant effect of a new class of quinoline derivatives (a-d) on assays in vitro. Lipid peroxidation, thiol peroxidase-like and free radical scavenging activities were determined to evaluate antioxidant activity of compounds. Thiol oxidase-like and δ-aminolevulinate dehydratase activities were performed as a toxicological parameter. A second objective of this study was to evaluate the in vivo antinociceptive effect of the compound with better antioxidant effect and without toxic effects in a model of nociception induced by formalin in mice...
May 22, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28535498/can-dmco-detect-visual-field-loss-in-neurological-patients-a-secondary-validation-study
#9
Ane Sophie Olsen, Alvilda Thougaard Steensberg, Morten la Cour, Troels Wesenberg Kjaer, Bertil Damato, Lars Hageman Pinborg, Miriam Kolko
Unrecognized visual field loss is caused by a range of blinding eye conditions as well as serious brain diseases. The commonest cause of asymptomatic visual field loss is glaucoma. No screening tools have been proven cost-effective. Damato Multifixation Campimetry Online (DMCO), an inexpensive online test, has been evaluated as a future cost-beneficial tool to detect glaucoma. To further validate DMCO, this study aimed to test DMCO in a preselected population with neurological visual field loss. METHODS: The study design was an evaluation of a diagnostic test...
May 24, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28527874/pressor-support-during-a-jarisch-herxheimer-reaction-after-initiation-of-treatment-for-weil-s-disease
#10
Randi Connor-Schuler, Anee Khan, Nikhil Goyal, Erin Zimny
We present a case of Weil's disease complicated by a Jarisch-Herxheimer reaction (JHR) after initiation of antibiotics while in the emergency department requiring invasive monitoring and vasopressor support. The case is followed by a brief review of the JHR which is rarely observed with treatment of leptospirosis. A healthy 28-year-old female who recently returned from the Caribbean presented to the emergency department with flu-like symptoms. The patient appeared jaundiced with conjunctival suffusion and was ultimately treated with the appropriate antibiotics for leptospirosis in the ED...
April 27, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28527673/minimal-access-surgery-compared-to-laparotomy-for-secondary-surgical-cytoreduction-in-patients-with-recurrent-ovarian-carcinoma-perioperative-and-oncologic-outcomes
#11
Ane Gerda Z Eriksson, Ashley Graul, Miao C Yu, Anthony Halko, Dennis S Chi, Oliver Zivanovic, Ginger J Gardner, Yukio Sonoda, Richard R Barakat, Nadeem R Abu-Rustum, Mario M Leitao
OBJECTIVES: To assess the perioperative outcomes of minimal access surgery (MAS) in secondary surgical cytoreduction (SSCR) for recurrent epithelial ovarian cancer (ROC); to compare oncologic outcomes with laparotomy (LAP). METHODS: Using an institutional database, we identified all patients with ROC undergoing SSCR from 1/5/09-6/14/14. Selection for MAS or LAP was based on surgeon preference. To minimize selection bias, preoperative imaging was reviewed for all LAP cases...
May 17, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28526204/the-786-t-c-polymorphism-of-nos3-gene-is-a-susceptibility-marker-of-copd-among-tunisians-that-correlates-with-nitric-oxide-levels-and-airflow-obstruction
#12
Hela Ben Nasr, Sarra Bchir, Amel Ben Anes, Asma Amri, Yosra Sakhana, Mohamed Benzarti, Abdelhamid Garrouch, Zouhair Tabka, Karim Chahed
OBJECTIVE: The goal of this study was to examine the role of G894T (rs1799983), -786T/C (rs3918161) and a 27 bp variable number of tandem repeats (VNTR) 4B/4A of NOS3 gene on the risk and severity of COPD. METHODS: The study included 194 controls and 138 COPD patients. NOS3 G894T, -786T/C and 4B/4A variants were determined by PCR analysis based on the banding pattern on gel electrophoresis. Pulmonary function was evaluated using body plethysmography. The levels of nitric oxide, peroxynitrite and lipid peroxides (T-BARS) were determined using spectrophotometric methods...
May 16, 2017: Cytokine
https://www.readbyqxmd.com/read/28521794/in-vitro-synthesis-of-9-10-dihydroxyhexadecanoic-acid-using-recombinant-escherichia-coli
#13
Anees Kaprakkaden, Preeti Srivastava, Virendra Swarup Bisaria
BACKGROUND: Hydroxy fatty acids are widely used in food, chemical and cosmetic industries. A variety of dihydroxy fatty acids have been synthesized so far; however, no studies have been done on the synthesis of 9,10-dihydroxyhexadecanoic acid. In the present study recombinant E. coli has been used for the heterologous expression of fatty acid hydroxylating enzymes and the whole cell lysate of the induced culture was used for in vitro production of 9,10-dihydroxyhexadecanoic acid. RESULTS: A first of its kind proof of principle has been successfully demonstrated for the production of 9,10-dihydroxyhexadecanoic acid using three different enzymes viz...
May 18, 2017: Microbial Cell Factories
https://www.readbyqxmd.com/read/28520088/clathrin-mediated-endocytosis-is-required-for-ane-30-100k-induced-autophagy
#14
Mei-Huei Lin, Young-Chau Liu, Shyun-Yeu Liu, Fang-Chi Chen, Pei-Jung Yang, Guan-Hua Li, Pang-Yen Liu, Ching-Yu Yen
BACKGROUND: We identified an autophagy-inducing areca nut (AN) ingredient (AIAI) in the 30-100 kDa fraction of AN extract (ANE 30-100K). This study was to analyze the role of endocytosis in ANE 30-100K-induced autophagy. METHODS: We used benzyl alcohol, dynasore, and shRNA of clathrin and dynamin to assess whether ANE 30-100K-induced cytotoxicity and accumulation of microtubule-associated protein 1 light chain 3 (LC3)-II were affected in oral (OECM-1) and esophageal (CE81T/VGH) carcinoma cells...
May 18, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28512604/traditional-dentistry-knowledge-among-serbs-in-several-balkan-countries
#15
Dragan V Ilic, Biljana Andjelski Radicevic, Anely Nedelcheva, Ivana Djurovic, Dejan Ostojic
BACKGROUND/AIM: There are still unrevealed treasures of traditional dental medicine, that is, the reason to investigate and present various ways in treatment of oral and orofacial tissues, as well as magic and religious elements involved in representative areas among Serbs. MATERIALS AND METHODS: Information was collected from the elderly non-professional folk dentists and herbalists with the additional help of local physicians and dentists that was done through questionnaire and personal interviews...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28505968/inflammation-amyloid-and-atrophy-in-the-aging-brain-relationships-with-longitudinal-changes-in-cognition
#16
Roser Sala-Llonch, Ane-Victoria Idland, Tom Borza, Leiv Otto Watne, Torgeir Bruun Wyller, Anne Brækhus, Henrik Zetterberg, Kaj Blennow, Kristine Beate Walhovd, Anders Martin Fjell
Amyloid deposition occurs in aging, even in individuals free from cognitive symptoms, and is often interpreted as preclinical Alzheimer's disease (AD) pathophysiology. YKL-40 is a marker of neuroinflammation, being increased in AD, and hypothesized to interact with amyloid-β (Aβ) in causing cognitive decline early in the cascade of AD pathophysiology. Whether and how Aβ and YKL-40 affect brain and cognitive changes in cognitively healthy older adults is still unknown. We studied 89 participants (mean age: 73...
May 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28501267/gender-equity-imbalance-in-electrocardiology-a-call-to-action
#17
EDITORIAL
E Clarke Whalen, G Xu, I Cygankiewicz, L Bacharova, W Zareba, J S Steinberg, L G Tereshchenko, A Baranchuk
Despite the increasing number of women entering the medical profession, senior positions and academic productivity in many fields of medicine remain to be men dominated. We explored gender equity in electrocardiology as perceived by recent academic productivity and also active participation (presidencies and board constituents) in both the International Society of Electrocardiology (ISE) and the International Society for Holter and Noninvasive Electrocardiology (ISHNE). Academic productivity was measured by authorship (first and senior) in the Journal of Electrocardiology (JECG) and the Annals of Noninvasive Electrocardiology (ANE) in 2015...
May 4, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28501062/systemic-propolis-adjuvant-to-nonsurgical-periodontal-treatment-may-aid-in-glycemic-control-and-periodontal-health-in-type-2-diabetes-of-long-duration
#18
Wenche S Borgnakke
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Propolis improves periodontal status and glycemic control in patients with type 2 DM and chronic periodontitis: A randomized clinical trial. El-Sharkawy HM, Anees MM, Van Dyke TE. J Periodontol 2016;87:1418-1426. SOURCE OF FUNDING: Information not available. TYPE OF STUDY/DESIGN: Randomized controlled trial (RCT).
June 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28498172/effectiveness-of-patient-safety-leadership-walkrounds%C3%A2-on-patient-safety-culture-a-systematic-review-protocol
#19
Ane-Sofie Sølvtofte, Palle Larsen, Sussie Laustsen
The review objective is to synthesize the effect of Patient Safety Leadership WalkRounds (PSLWs) on patient safety culture (PSC).Specifically, the review question is: What is the effect of PSLWs on the PSC in hospitals, measured with validated surveys?
May 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28495686/incidence-of-non-pulmonary-cancer-and-lung-cancer-by-amount-of-emphysema-and-airway-wall-thickness-a-community-based-cohort
#20
Ane Aamli Gagnat, Miriam Gjerdevik, Frode Gallefoss, Harvey O Coxson, Amund Gulsvik, Per Bakke
There is limited knowledge about the prognostic value of quantitative computed tomography (CT) measures of emphysema and airway wall thickness in cancer.The aim of this study was to investigate if using CT to quantitatively assess the amount of emphysema and airway wall thickness independently predicts the subsequent incidence of non-pulmonary cancer and lung cancer.In the GenKOLS study of 2003-2005, 947 ever-smokers performed spirometry and underwent CT examination. The main predictors were the amount of emphysema measured by the percentage of low attenuation areas (%LAA) on CT and standardised measures of airway wall thickness (AWT-PI10)...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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