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https://www.readbyqxmd.com/read/28102982/requirements-for-notification-evaluation-and-reduction-of-lead-based-paint-hazards-in-federally-owned-residential-property-and-housing-receiving-federal-assistance-response-to-elevated-blood-lead-levels-final-rule
#1
(no author information available yet)
This final rule amends HUD's lead-based paint regulations to reduce blood lead levels in children under age six (6) who reside in federally-owned or -assisted pre-1978 housing, formally adopting a revised definition of "elevated blood lead level" (EBLL) in children under the age of six (6), in accordance with Centers for Disease Control and Prevention (CDC) guidance. It also establishes more comprehensive testing and evaluation procedures for the housing where such children reside. This final rule also addresses certain additional elements of the CDC guidance pertaining to assisted housing and makes technical corrections and clarifications...
13, 2017: Federal Register
https://www.readbyqxmd.com/read/28102964/plasmonic-chirality-imprinting-on-nucleobase-displaying-supramolecular-nanohelices-by-metal-nucleobase-recognition
#2
Yiyang Lin, E Thomas Pashuck, Michael R Thomas, Nadav Amdursky, Shih-Ting Wang, Lesley W Chow, Molly M Stevens
Supramolecular self-assembly is an important process that enables the conception of complex structures mimicking biological motifs. Herein, we constructed helical fibrils through chiral self-assembly of nucleobase-peptide conjugates (NPCs), where achiral nucleobases are helically displayed on the surface of fibrils, comparable to polymerized nucleic acids. Selective binding between DNA and the NPC fibrils was observed with fluorescence polarization. Taking advantage of metal-nucleobase recognition, we highlight the possibility of deposition/assembly of plasmonic nanoparticles onto the fibrillar constructs...
January 19, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28102949/simultaneous-pet-mr-imaging-with-a-radio-frequency-penetrable-pet-insert
#3
Alexander M Grant, Brian J Lee, Chen-Ming Chang, Craig S Levin
PURPOSE: A brain sized radio frequency (RF)-penetrable PET insert has been designed for simultaneous operation with MRI systems. This system takes advantage of electro-optical coupling and battery power to electrically float the PET insert relative to the MRI ground, permitting RF signals to be transmitted through small gaps between the modules that form the PET ring. This design facilitates the use of the built-in body coil for RF transmission and thus could be inserted into any existing MR site wishing to achieve simultaneous PET/MR imaging...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102944/a-simple-and-robust-trajectory-based-stereotactic-radiosurgery-treatment
#4
Byron Wilson, Karl Otto, Ermias Gete
INTRODUCTION: We present a Trajectory-based Volumetric Modulated Arc Therapy (TVMAT) technique for Stereotactic Radiosurgery (SRS) that takes advantage of a modern linacs ability to modulate dose rate and move the couch dynamically. In addition, we investigate the quality of the developed TVMAT method and the dosimetric accuracy of the technique. METHODS: The main feature of the TVMAT technique is a standard beam trajectory formed by dynamic motion of the treatment couch and the linac gantry...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102928/reduction-in-colposcopy-workload-and-associated-clinical-activity-following-hpv-catch-up-vaccination-programme-in-scotland-an-ecological-study
#5
M E Cruickshank, J Pan, S C Cotton, K Kavanagh, C Robertson, K Cuschieri, H Cubie, T Palmer, K G Pollock
OBJECTIVE: To measure patterns of clinical activity at colposcopy before and after vaccinated women entered the Scottish Cervical Screening Programme (SCSP). DESIGN: Population-based observational study using nationally collected data. SETTING: Scottish colposcopy clinics. SAMPLE: All women with a date of birth on or after 1 January 1985 who attended colposcopy in Scotland between 2008-2014. METHODS: Routinely collected data from the Scottish National Colposcopy Clinical Information Audit System (NCCIAS) was extracted, including: referral criteria, referral cervical cytology, colposcopic findings, clinical procedures and histology results...
January 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28102924/current-practices-related-to-family-presence-during-acute-deterioration-in-adult-emergency-department-patients
#6
Megan J Youngson, Judy Currey, Julie Considine
AIMS: To explore the characteristics and interactions of clinicians, patients and family members during management of the deteriorating adult patient in the Emergency Department. BACKGROUND: Previous research into family presence during resuscitation has identified many positive outcomes when families are included. However, over that last three decades the epidemiology of acute clinical deterioration has changed, with a decrease in in-hospital cardiac arrests and an increase in acute clinical deterioration...
January 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28102917/sexual-violence-in-the-college-population-a-systematic-review-of-disclosure-and-campus-resources-and-services
#7
REVIEW
Valerie Halstead, Jessica R Williams, Rosa Gonzalez-Guarda
AIMS AND OBJECTIVES: To synthesize research examining college student sexual violence disclosure and campus sexual violence resources and services. BACKGROUND: Recently, the issue of sexual violence within the college population has garnered attention worldwide. The prevalence of sexual violence within college students is alarmingly high. Survivors often experience negative outcomes (e.g., health-related consequences, impact on education). Efforts have been made to address this significant public health concern...
January 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28102915/transgenerational-effects-alter-plant-defense-and-resistance-in-nature
#8
Jack Colicchio
Trichomes, or leaf hairs, are epidermal extensions that take a variety of forms and perform many functions in plants, including herbivore defense. In this study, I document genetically determined variation, within-generation plasticity, and a direct role of trichomes in herbivore defense for Mimulus guttatus. After establishing the relationship between trichomes and herbivory, I test for transgenerational effects of wounding on trichome density and herbivore resistance. Patterns of inter-annual variation in herbivore density and the high cost of plant defense makes plant-herbivore interactions a system in which transgenerational phenotypic plasticity (TPP) is apt to evolve...
January 19, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28102835/spinal-cord-regeneration-in-xenopus-laevis
#9
Gabriela Edwards-Faret, Rosana Muñoz, Emilio E Méndez-Olivos, Dasfne Lee-Liu, Victor S Tapia, Juan Larraín
Here we present a protocol for the husbandry of Xenopus laevis tadpoles and froglets, and procedures to study spinal cord regeneration. This includes methods to induce spinal cord injury (SCI); DNA and morpholino electroporation for genetic studies; in vivo imaging for cell analysis; a swimming test to measure functional recovery; and a convenient model for screening for new compounds that promote neural regeneration. These protocols establish X. laevis as a unique model organism for understanding spinal cord regeneration by comparing regenerative and nonregenerative stages...
February 2017: Nature Protocols
https://www.readbyqxmd.com/read/28102773/the-optimal-duration-of-anticoagulant-therapy-after-unprovoked-venous-thromboembolism-still-a-challenging-issue
#10
Giovanna Elmi, Giuseppe Di Pasquale, Raffaele Pesavento
As about 50 % of patients with unprovoked venous thromboembolism (VTE) will develop new episodes after discontinuing therapy, indefinite treatment is suggested in patients with low or moderate bleeding risk. Baseline and post-baseline factors can help clinicians to identify patients at high risk of recurrence, who require extended treatment. Residual vein obstruction and D-dimer assay have been shown to be suitable methods for assessing the risk of VTE recurrences after a first unprovoked VTE. In treatment for VTE the use of direct oral anticoagulants (DOAC) is growing instead of the standard adjusted dose of vitamin K antagonists...
January 19, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28102580/the-sliding-context-of-health-the-challenges-faced-by-patients-with-heart-failure-from-the-perspective-of-patients-health-care-providers-and-family-members
#11
Parvin Mangolian Shahrbabaki, Esmat Nouhi, Majid Kazemi, Fazlollah Ahmadi
AIMS AND OBJECTIVES: The aim of this study was to understand the challenges faced by patients with heart failure. BACKGROUND: Heart failure is a clinical syndrome that is increasing across the globe. People affected with it, encounter various problems that reduce their quality of life and well-being. Therefore, identifying the challenges faced by patients with heart failure is necessary for health care and treatment plans. DESIGN: This study was performed using the qualitative research approach and content analysis method...
January 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28102551/foliar-uptake-of-radiocaesium-from-irrigation-water-by-paddy-rice%C3%A2-oryza-sativa-an-overlooked-pathway-in-contaminated-environments
#12
Shinichiro Uematsu, Hildegarde Vandenhove, Lieve Sweeck, May Van Hees, Jean Wannijn, Erik Smolders
Flooded (paddy) rice (Oryza sativa) can take up ions from the irrigation water by foliar uptake via the exposed stem base. We hypothesised that the stem base uptake of radiocaesium (RCs) is a pathway for rice grown in RCs-contaminated environments. We developed a bi-compartmental device which discriminates the stem base from root RCs uptake from solutions, thereby using RCs isotopes ((137) Cs and (134) Cs) with < 2% solution leak between the compartments. Radiocaesium uptake was linear over time (0-24 h)...
January 19, 2017: New Phytologist
https://www.readbyqxmd.com/read/28102490/genome-engineering-of-stem-cell-organoids-for-disease-modeling
#13
REVIEW
Yingmin Sun, Qiurong Ding
Precision medicine emerges as a new approach that takes into account individual variability. Successful realization of precision medicine requires disease models that are able to incorporate personalized disease information and recapitulate disease development processes at the molecular, cellular and organ levels. With recent development in stem cell field, a variety of tissue organoids can be derived from patient specific pluripotent stem cells and adult stem cells. In combination with the state-of-the-art genome editing tools, organoids can be further engineered to mimic disease-relevant genetic and epigenetic status of a patient...
January 19, 2017: Protein & Cell
https://www.readbyqxmd.com/read/28102407/introducing-tetramethylurea-as-a-new-methylene-precursor-a-microwave-assisted-rucl3-catalyzed-cross-dehydrogenative-coupling-approach-to-bis-indolyl-methanes
#14
Mohit L Deb, Paran J Borpatra, Prakash J Saikia, Pranjal K Baruah
Herein we report a microwave assisted Ru(iii)/TBHP-mediated reaction of indoles with tetramethylurea (TMU) synthesizing symmetrical as well as unsymmetrical bis(indolyl)methanes, where TMU acts as a methylenating agent. This is the first report where TMU is used as a methylene source. Moreover, the synthesis of unsymmetrical bis(indolyl)methanes by using a carbon precursor is also reported herein for the first time. Various substituted indoles are used for the reaction. The reaction is high yielding and takes a much shorter time to accomplish compared to the existing methods...
January 19, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28102314/improved-solar-driven-photocatalytic-performance-of-highly-crystalline-hydrogenated-tio2-nanofibers-with-core-shell-structure
#15
Ming-Chung Wu, Ching-Hsiang Chen, Wei-Kang Huang, Kai-Chi Hsiao, Ting-Han Lin, Shun-Hsiang Chan, Po-Yeh Wu, Chun-Fu Lu, Yin-Hsuan Chang, Tz-Feng Lin, Kai-Hsiang Hsu, Jen-Fu Hsu, Kun-Mu Lee, Jing-Jong Shyue, Krisztián Kordás, Wei-Fang Su
Hydrogenated titanium dioxide has attracted intensive research interests in pollutant removal applications due to its high photocatalytic activity. Herein, we demonstrate hydrogenated TiO2 nanofibers (H:TiO2 NFs) with a core-shell structure prepared by the hydrothermal synthesis and subsequent heat treatment in hydrogen flow. H:TiO2 NFs has excellent solar light absorption and photogenerated charge formation behavior as confirmed by optical absorbance, photo-Kelvin force probe microscopy and photoinduced charge carrier dynamics analyses...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28102229/the-neurosteroidogenic-enzyme-5%C3%AE-reductase-mediates-psychotic-like-complications-of-sleep-deprivation
#16
Roberto Frau, Valentina Bini, Alessio Soggiu, Simona Scheggi, Alessandra Pardu, Silvia Fanni, Paola Roncada, Monica Puligheddu, Francesco Marrosu, Donatella Caruso, Paola Devoto, Marco Bortolato
Acute sleep deprivation (SD) can trigger or exacerbate psychosis- and mania-related symptoms; the neurobiological basis of these complications, however, remains elusive. Given the extensive involvement of neuroactive steroids in psychopathology, we hypothesized that the behavioral complications of SD may be contributed by 5α-reductase (5αR), the rate-limiting enzyme in the conversion of progesterone into the neurosteroid allopregnanolone. We first tested whether rats exposed to SD may exhibit brain-regional alterations in 5αR isoenzymes and neuroactive steroid levels; then, we assessed whether the behavioral and neuroendocrine alterations induced by SD may be differentially modulated by the administration of the 5αR inhibitor finasteride, as well as progesterone and allopregnanolone...
January 19, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28102179/a-2-d-suspension-of-active-agents-the-role-of-fluid-mediated-interactions
#17
Hojjat Behmadi, Zahra Fazli, Ali Najafi
Taking into account both the Vicsek short range ordering and the far-field hydrodynamic interactions mediated by the ambient fluid, we investigate the role of long range interactions in the ordering phenomena in a quasi 2-dimensional active suspension. By studying the number fluctuations, the velocity correlation functions and cluster size distribution function, we show that depending on the number density of swimmers and the strength of noise, the hydrodynamic interactions can have significant effects in a suspension...
January 19, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28102174/modeling-dynamics-of-mutants-in-heterogeneous-stem-cell-niche
#18
Leili Shahriyari, Ali Mahdipour Shirayeh
Studying the stem cell (SC) niche architecture is a crucial step for investigating the process of oncogenesis and obtaining an effective stem cell therapy for various cancers. Recently, it has been observed that there are two groups of SCs in the SC niche collaborating with each other to maintain tissue homeostasis: border stem cells (BSCs), which are responsible in controlling the number of non-stem cells as well as stem cells, and central stem cells (CeSCs), which regulate the SC niche. Here, we develop a bi-compartmental stochastic model for the SC niche to study the spread of mutants within the niche...
January 19, 2017: Physical Biology
https://www.readbyqxmd.com/read/28102170/complication-of-a-femoral-fracture-treated-by-intramedullary-nailing-numerical-analysis-of-a-clinical-case
#19
Jakub J Słowiński, Konrad Kudłacik
The aim of this paper is to conduct a numerical analysis of a case of femoral fracture treated by intramedullary nailing and confirm the conditions which led to the formation of a pseudarthrosis at the fracture site. A low-energy femoral fracture was treated by placing a ChFN System intramedullary nail with a derotation pin. Using the finite element method, a bone-implant system was generated which made it possible to observe the displacement area and strains in the region of the fracture gap. The calculations were conducted for 3 variants of the model, using a titanium nail (10 mm and 12 mm) and a steel one (10 mm)...
August 30, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28102167/assessment-and-comparison-of-the-efficacy-of-rehabilitation-conducted-at-a-sanatorium-and-in-an-outpatient-facility-in-patients-with-low-back-pain-pilot-study
#20
Jakub Szewczyk
BACKGROUND: Low back pain is nowadays believed to be one of the most serious and common health problems and is even often classified as a disease of civilisation. Prevention and treatment of such conditions is very important, particularly taking into consideration the fact that they are increasingly common in young people. Low back pain is effectively prevented and treated with rehabilitation. The aim of this paper was to assess and compare rehabilitation procedures performed in patients with low back pain in the sanatorium setting and on an outpatient basis...
August 30, 2016: Ortopedia, Traumatologia, Rehabilitacja
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