keyword
Keywords estimated glomerular filtratio...

estimated glomerular filtration rate

https://read.qxmd.com/read/38536864/sex-related-differences-in-pre-dialysis-trajectories-and-dialysis-initiation-a-french-nationwide-retrospective-study
#1
JOURNAL ARTICLE
Maxime Raffray, Louise Bourasseau, Cécile Vigneau, Cécile Couchoud, Clémence Béchade, François Glowacki, Sahar Bayat
BACKGROUND: In the last two decades, sex and gender differences have been documented in chronic kidney disease (CKD) management, including access to renal replacement therapy and its outcomes. The objectives of this study were to 1) compare the pre-dialysis healthcare utilization in men and women, and 2) examine the sex-specific factors associated with emergency dialysis start. METHODS: Adult patients with CKD who started dialysis in France in 2015 were extracted from the Renal Epidemiology and Information Network registry...
2024: PloS One
https://read.qxmd.com/read/38534505/biomedical-evaluation-of-early-chronic-kidney-disease-in-the-air-force-building-a-predictive-model-from-the-taiwan-military-health-service
#2
JOURNAL ARTICLE
Po-Jen Hsiao, Ruei-Lin Wang, Fu-Kang Hu, Fu-Ru Tsai, Chih-Chien Chiu, Wen-Fang Chiang, Kun-Lin Wu, Yuan-Kuei Li, Jenq-Shyong Chan, Chi-Ming Chu, Chi-Wen Chang
OBJECTIVE: Chronic kidney disease (CKD) is one of the most common diseases worldwide. The increasing prevalence and incidence of CKD have contributed to the critical problem of high medical costs. Due to stressful environments, aircrew members may have a high risk of renal dysfunction. A better strategy to prevent CKD progression in Air Force personnel would be to diagnosis CKD at an early stage. Since few studies have been conducted in Taiwan to examine the long-term trends in early CKD in Air Force aircrew members, this study is highly important...
February 28, 2024: Bioengineering
https://read.qxmd.com/read/38533961/correlates-of-plasma-nt-probnp-cyclic-gmp-ratio-in-heart-failure-with-preserved-ejection-fraction-an-analysis-of-the-relax-trial
#3
JOURNAL ARTICLE
Leonard Chiu, Vineet Agrawal, David Armstrong, Evan Brittain, Sheila Collins, Anna R Hemnes, Joseph A Hill, JoAnn Lindenfeld, Sanjiv J Shah, Lynne W Stevenson, Thomas J Wang, Deepak K Gupta
BACKGROUND: Phosphodiesterases degrade cyclic GMP (cGMP), the second messenger that mediates the cardioprotective effects of natriuretic peptides. High natriuretic peptide/cGMP ratio may reflect, in part, phosphodiesterase activity. Correlates of natriuretic peptide/cGMP in patients with heart failure with preserved ejection fraction are not well understood. Among patients with heart failure with preserved ejection fraction in the RELAX (Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in Heart Failure With Preserved Ejection Fraction) trial, we examined (1) cross-sectional correlates of circulating NT-proBNP (N-terminal pro-B-type natriuretic peptide)/cGMP ratio, (2) whether selective phosphodiesterase-5 inhibition by sildenafil changed the ratio, and (3) whether the effect of sildenafil on 24-week outcomes varied by baseline ratio...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533430/serum-cell-division-cycle%C3%A2-42-reflects-the-development-and-progression-of-diabetic-nephropathy-in-patients-with-diabetes-mellitus
#4
JOURNAL ARTICLE
Hongyu Yu, Jian Ma, Yueru Gu, Wei Zou, Na Zhao
Cell division cycle 42 (CDC42) regulates podocyte apoptosis to take part in the development and progression of diabetic nephropathy (DN), but currently the clinical evidence is limited. The aim of the present study was to investigate the capability of serum CDC42 expression level to estimate the development and progression of DN in patients with diabetes mellitus (DM). Patients with type 2 DM (n=306) were enrolled and divided into normoalbuminuria (n=185), microalbuminuria (n=72) and macroalbuminuria (n=49) groups based on the urinary albumin-to-creatinine ratio...
May 2024: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/38533279/sglt2-inhibitors-paradigm-shift-from-diabetes-care-to-metabolic-care-an-indian-perspective
#5
REVIEW
K M Prasanna Kumar, A G Unnikrishnan, Pankaj Jariwala, Ashwani Mehta, Richa Chaturvedi, Sagar Panchal, Preet Lakhani, Rachana Acharya, Jitendra Dixit
The prevalence and burden of diabetes are on the rise in India, making it 'the diabetes capital of the world'. Comorbidities such as obesity, cardiovascular (CV) complications, chronic kidney disease (CKD), non-alcoholic fatty liver disease (NAFLD), and neurodegenerative diseases are common in patients with diabetes. Recent breakthroughs in diabetes medications and continuous glucose monitoring have resulted in a paradigm shift in diabetes care. Hence, a review in the Indian context is warranted. This review focuses on the existing evidence (gathered by a systematic literature search utilising online databases such as PubMed) on the metabolic, cardio-renoprotective, and hepatoprotective effects of sodium-glucose co-transporter 2 (SGLT2) inhibition, particularly in the Indian setting...
2024: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38532529/use-of-kidney-failure-risk-equation-as-a-tool-to-evaluate-referrals-from-primary-care-to-specialist-nephrology-care
#6
JOURNAL ARTICLE
Katherine Li, Saiyini Pirabhahar, Max Thomsett, Kylie Turner, Marina Wainstein, Jeff T Ha, Ivor Katz
BACKGROUND: With rising costs and burden of chronic kidney disease (CKD), timely referral of patients to a kidney specialist is crucial. Currently, Kidney Health Australia (KHA) uses a 'heat map' based on severity and not future risk of kidney failure, whereas the kidney failure risk equation (KFRE) score predicts future risk of progression. AIMS: Evaluate whether a KFRE score assists with timing of CKD referrals. METHODS: Retrospective cohort of 2137 adult patients, referred to tertiary hospital outpatient nephrologist between 2012 and 2020, were analysed...
March 26, 2024: Internal Medicine Journal
https://read.qxmd.com/read/38532270/a-population-pharmacokinetic-model-using-allometric-scaling-for-baricitinib-in-patients-with-juvenile-idiopathic-arthritis
#7
JOURNAL ARTICLE
Rodney L Decker, C Steven Ernest, David B Radtke, Rona Wang, Joana Araújo, Stuart Y Keller, Xin Zhang
Baricitinib is approved for the treatment of rheumatoid arthritis (RA) in more than 70 countries, and juvenile idiopathic arthritis (JIA) in the European Union. Population pharmacokinetic (PK) models were developed in a phase 3 trial to characterize PK in pediatric patients with JIA and identify weight-based dosing regimens. The phase 3, randomized, double-blind, placebo-controlled withdrawal, efficacy and safety trial, JUVE-BASIS, enrolled patients (aged 2 to <18 years) with polyarticular course JIA...
March 26, 2024: CPT: Pharmacometrics & Systems Pharmacology
https://read.qxmd.com/read/38531765/osteoporosis-management-in-patients-with-chronic-kidney-disease-ercos-study-a-challenge-in-nephrological-care
#8
JOURNAL ARTICLE
Jordi Bover, Carlos Gómez-Alonso, Enrique Casado, Minerva Rodríguez-García, María Jesús Lloret, Cristina Castro-Alonso, Laia Gifre, Fernando Henríquez-Palop, Águeda Prior-Español, Virginia López de la Manzanara, Ana María Láiz, Àngels Martínez-Ferrer, Josep Vicens Torregrosa, Secundino Cigarrán, José Luis Górriz, Marco Montomoli, Nayara Panizo, Ester Costa, Daniel Martínez-Laguna, Mariano Rodríguez, Juan F Navarro-González
Fracture risk assessment in patients with chronic kidney disease (CKD) has been included in the CKD-MBD ("Chronic Kidney Disease-Mineral and Bone Disorders") complex in international and national nephrology guidelines, suggesting for the first time the assessment of bone mineral density (BMD) if the results can influence therapeutic decision-making. However, there is very little information on actual clinical practice in this population. The main objective of the ERCOS (ERC-Osteoporosis) study is to describe the profile of patients with CKD G3-5D with osteoporosis (OP) and/or fragility fractures treated in specialized nephrology, rheumatology and internal medicine clinics in Spain...
March 25, 2024: Nefrología
https://read.qxmd.com/read/38531564/investigation-of-renal-perfusion-and-pathological-changes-in-patients-with-acute-kidney-disease-and-tubulointerstitial-nephritis-using-intravoxel-incoherent-motion-and-arterial-spin-labelling-mri-a-prospective-observational-study-protocol
#9
JOURNAL ARTICLE
Jiajia Liu, Rui Wang, Jianxing Qiu, Tao Su
INTRODUCTION: Acute kidney injury (AKI) is a critical condition with a complex aetiology and different outcomes, where haemodynamic dysfunction, renal hypoperfusion and inflammation serve as key contributors to its development and progression. Early and accurate diagnosis is vital for initiating targeted treatments like fluid resuscitation, vasoactive agents or steroid therapy, which are essential for improving patient outcomes. Intravoxel incoherent motion (IVIM) MRI assesses both capillary perfusion and tissue water diffusion, while arterial spin labelling (ASL) MRI measures renal blood flow without the need for contrast...
March 25, 2024: BMJ Open
https://read.qxmd.com/read/38530931/imaging-markers-from-population-wide-mri-based-automated-kidney-segmentation-an-analysis-of-data-from-the-german-national-cohort-nako-gesundheitsstudie
#10
Elias Kellner, Peggy Sekula, Jan Lipovsek, Maximilian Russe, Harald Horbach, Christopher L Schlett, Matthias Nauck, Henry Völzke, Thomas Kroencke, Stefanie Bette, Hans-Ulrich Kauczor, Thomas Keil, Tobias Pischon, Iris M Heid, Annette Peters, Thoralf Niendorf, Wolfgang Lieb, Fabian Bamberg, Martin Büchert, Wilfried Reichardt, Marco Reisert, Anna Köttgen
BACKGROUND: Population-wide research on potential new imaging biomarkers of the kidney depends on accurate automated segmentation of the kidney and its compartments (cortex, medulla, and sinus). METHODS: We developed a robust deep-learning framework for kidney (sub-)segmentation based on a hierarchical, three-dimensional convolutional neural network (CNN) that was optimized for multi-scale problems of combined localization and segmentation. We applied the CNN to abdominal magnetic resonance images from the population-based German National Cohort (NAKO) study...
May 3, 2024: Deutsches Ärzteblatt International
https://read.qxmd.com/read/38529168/prognostic-value-of-hemoglobin-concentration-on-renal-outcomes-with-diabetic-kidney-disease-a-retrospective-cohort-study
#11
JOURNAL ARTICLE
Xiaojie Chen, Jianteng Xie, Yifan Zhang, Shaogui Zhang, Sheng Li, Min Lu, Danfeng Liu, Weiting He, Hokhim Yau, Runli Jia, Yaxi Zhu, Wenjian Wang
OBJECTIVE: Diabetic kidney disease (DKD) patients with anemia face an elevated risk of glomerular filtration rate decline. However, the association between hemoglobin and estimated Glomerular Filtration Rate (eGFR) progression remains to be elucidated. METHODS: A retrospective cohort of 815 subjects with DKD was followed from January 2010 to January 2023. A Cox proportional hazard regression model was utilized to explore the predictive role of hemoglobin in renal outcomes...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38528820/comparison-of-estimated-glomerular-filtration-rate-change-with-sodium-glucose-cotransporter-2-inhibitors-versus-glucagon-like-peptide-1-receptor-agonists-among-people-with-diabetes-a-propensity-score-matching-study
#12
JOURNAL ARTICLE
Yuta Suzuki, Hidehiro Kaneko, Hajime Nagasawa, Akira Okada, Katsuhito Fujiu, Taisuke Jo, Norifumi Takeda, Hiroyuki Morita, Akira Nishiyama, Tomohito Gohda, Yusuke Suzuki, Koichi Node, Hideo Yasunaga, Masaomi Nangaku, Issei Komuro
AIM: To compare the risk of developing kidney outcomes with use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) versus use of sodium-glucose cotransporter-2 (SGLT2) inhibitors among individuals with diabetes. MATERIALS AND METHODS: In this retrospective observational study, we analysed 12 338 individuals with diabetes who newly initiated SGLT2 inhibitors or GLP-1RAs using data from the JMDC claims database. The primary outcome was change in the estimated glomerular filtration rate (eGFR), estimated using a linear mixed-effects model...
March 26, 2024: Diabetes, Obesity & Metabolism
https://read.qxmd.com/read/38528676/correlations-between-serum-kidney-injury-molecule-1-cystatin-c-and-immunosuppressants-a-cross-sectional-study-of-renal-transplant-patients-in-bahrain
#13
JOURNAL ARTICLE
Kannan Sridharan, Shamik Shah, Mona Al Hammad, Fatima Ali Mohammed, Sindhan Veeramuthu, Mona Abdulla Taher, Mustafa Mohamed Hammad, Lamees Jawad, Eman Farid
Renal transplant patients receive several immunosuppressive drug regimens that are potentially nephrotoxic for treatment. Serum creatinine is the standard for monitoring kidney function; however, cystatin C (Cys C) and kidney injury molecule-1 (KIM-1) have been found to indicate kidney injury earlier than serum creatinine and provide a better reflection of kidney function. Here, we assessed Cys C and KIM-1 serum levels in renal transplant patients receiving mycophenolate mofetil, tacrolimus, sirolimus, everolimus, or cyclosporine to evaluate kidney function...
March 26, 2024: Journal of Biomedical Research
https://read.qxmd.com/read/38528482/effect-of-multidisciplinary-care-on-diabetic-kidney-disease-a-retrospective-cohort-study
#14
JOURNAL ARTICLE
Ayano Hayashi, Kayoko Mizuno, Kanna Shinkawa, Kazunori Sakoda, Satomi Yoshida, Masato Takeuchi, Motoko Yanagita, Koji Kawakami
BACKGROUND: Diabetic kidney disease (DKD) is the most common disease among patients requiring dialysis for the first time in Japan. Multidisciplinary care (MDC) may prevent the progression of kidney failure. However, the effectiveness and timing of MDC to preserve kidney function in patients with DKD is unclear. Therefore, the aim of this study was to investigate whether MDC for patients with DKD affects the preservation of kidney function as well as the timing of MDC in clinical practice...
March 25, 2024: BMC Nephrology
https://read.qxmd.com/read/38528373/serum-t-50-predicts-cardiovascular-mortality-in-individuals-with-type-2-diabetes-a-prospective-cohort-study
#15
JOURNAL ARTICLE
Amarens van der Vaart, Coby Eelderink, Harry van Goor, Jan-Luuk Hillebrands, Charlotte A Te Velde-Keyzer, Stephan J L Bakker, Andreas Pasch, Peter R van Dijk, Gozewijn D Laverman, Martin H de Borst
BACKGROUND AND AIMS: Individuals with type 2 diabetes (T2D) have a higher risk of cardiovascular disease, compared with those without T2D. The serum T50 test captures the transformation time of calciprotein particles in serum. We aimed to assess whether serum T50 predicts cardiovascular mortality in T2D patients, independent of traditional risk factors. METHODS: We analyzed 621 individuals with T2D in this prospective cohort study. Cox regression models were performed to test the association between serum T50 and cardiovascular and all-cause mortality...
March 25, 2024: Journal of Internal Medicine
https://read.qxmd.com/read/38526448/linking-renal-hypoxia-and-oxidative-stress-in-chronic-kidney-disease-based-on-clinical-subjects-and-animal-models
#16
JOURNAL ARTICLE
Yizeng Xu, Fang Lu, Meng Wang, Lingchen Wang, Chaoyang Ye, Shuohui Yang, Chen Wang
This study aims to explore the relationships between renal function, hypoxia, and oxidative stress in chronic kidney disease (CKD). Seventy-six non-dialysis patients with CKD stages 1-5 and eight healthy subjects were included in the clinical research. They were divided into three groups: healthy subjects, CKD stages 1-3, and CKD stages 4-5. In the animal study, 16 rat models of CKD were established through 5/6 renal ablation/infarction (A/I) surgery, and 8 normal rats were split into 3 groups: Sham, CKD, and losartan groups...
March 24, 2024: Biomol Biomed
https://read.qxmd.com/read/38525743/impact-of-antibiotics-used-for-acute-aspiration-bronchitis-on-the-prevention-of-pneumonia
#17
JOURNAL ARTICLE
Akihiko Goto, Kosaku Komiya, Kenji Umeki, Kazufumi Hiramatsu, Jun-Ichi Kadota
BACKGROUNDS: It remains unclear if antibiotics should be used for the treatment of acute aspiration bronchitis to prevent the development of pneumonia. This study aimed to assess the associations between the use of antibiotics and the development of pneumonia among patients with acute aspiration bronchitis. METHODS: We retrospectively reviewed consecutive patients with acute aspiration bronchitis aged ≥75 years. Acute aspiration bronchitis was defined as a condition with aspiration risk, high fever (body temperature, ≥37...
February 25, 2024: Geriatrics
https://read.qxmd.com/read/38524941/predictive-patterns-of-lower-urinary-tract-symptoms-and-bacteriuria-in-adults-with-type-2-diabetes
#18
JOURNAL ARTICLE
Keiji Sugai, Junko Sasaki, Yuki Wada, Norihiro Shimizu, Takuya Ishikawa, Ketchu Yanagi, Takeshi Hashimoto, Akihiko Tanaka, Hirotsugu Suwanai, Ryo Suzuki, Masato Odawara
BACKGROUND: Numerous studies demonstrated the risk factors for urological complications in patients with diabetes before sodium-glucose co-transporter 2 inhibitor (SGLT2i) became commercially available. This study aimed to comprehensively investigate urological characteristics in patients with type 2 diabetes (T2DM) after SGLT2i became commercially available. METHODS: We examined 63 outpatients with T2DM suspected of bacteriuria based on urinary sediment examinations...
April 2024: Diabetology International
https://read.qxmd.com/read/38524801/impact-of-the-2021-ckd-epi-egfr-equation-on-kidney-care-referral-criteria-in-ontario-canada-a-population-based-cross-sectional-study
#19
JOURNAL ARTICLE
Eric McArthur, Graham Smith, Manish M Sood, Peter G Blake, K Scott Brimble, Flory T Muanda, Amit X Garg, Stephanie N Dixon
BACKGROUND: In some jurisdictions, individuals become eligible or recommended for referral for different types of kidney care using criteria based on their estimated glomerular filtration rate (eGFR). Historically, GFR was estimated with an equation developed in 2009, which included a Black race term. An updated, race-free equation was developed in 2021. It is unclear how adoption of the 2021 equation will influence the number of individuals meeting referral criteria to receive different types of kidney care...
2024: Canadian Journal of Kidney Health and Disease
https://read.qxmd.com/read/38522954/the-association-between-monocyte-to-high-density-lipoprotein-cholesterol-ratio-and-chronic-kidney-disease-in-a-chinese-adult-population-a-cross-sectional-study
#20
JOURNAL ARTICLE
Lingling Xu, Dongling Li, Zongwei Song, Jin Liu, Yang Zhou, Junwei Yang, Ping Wen
BACKGROUND: Monocyte to high-density lipoprotein cholesterol ratio (MHR) was confirmed as a novel inflammatory marker and strongly associated with the risk of several diseases. This study aimed to investigate the relationship between MHR and chronic kidney disease (CKD) in a Chinese adult population. METHODS: In this cross-sectional study, 232,775 community-dwelling adults in Binhai who completed health checkups in 2021 were enrolled. Participants were categorized based on the MHR quartiles...
December 2024: Renal Failure
keyword
keyword
17464
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.