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https://www.readbyqxmd.com/read/28549144/video-assisted-thoracoscopic-surgery-approach-for-transmyocardial-laser-revascularization
#1
Mohammad A Bashir, Brandon C Lyle, Ali S Nasr, Kalpaj Parekh
Transmyocardial laser revascularization is an established therapy for refractory coronary artery disease. However, utilization of the technology is not as widespread as expected. This is despite the fact that the efficacy of the technology has been established in multiple prospective randomized trials. Furthermore, only about 5% of transmyocardial laser revascularization cases annually are performed in a minimally invasive fashion. We report a case of a female patient treated in a minimally invasive thoracoscopic fashion...
May 26, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28549119/systematic-review-of-cost-effectiveness-of-myocardial-perfusion-scintigraphy-in-patients-with-ischaemic-heart-disease-a-report-from-the-cardiovascular-committee-of-the-european-association-of-nuclear-medicine-endorsed-by-the-european-association-of-cardiovascular
#2
Elin Trägårdh, Siok Swan Tan, Jan Bucerius, Alessia Gimelli, Oliver Gaemperli, Oliver Lindner, Denis Agostini, Christopher Übleis, Roberto Sciagrà, Riemer H Slart, S Richard Underwood, Fabien Hyafil, Marcus Hacker, Hein J Verberne
Coronary artery disease (CAD) is a major cause of death and disability. Several diagnostic tests, such as myocardial perfusion scintigraphy (MPS), are accurate for the detection of CAD, as well as having prognostic value for the prediction of cardiovascular events. Nevertheless, the diagnostic and prognostic value of these tests should be cost-effective and should lead to improved clinical outcome. We have reviewed the literature on the cost-effectiveness of MPS in different circumstances: (i) the diagnosis and management of CAD; (ii) comparison with exercise electrocardiography (ECG) and other imaging tests; (iii) as gatekeeper to invasive coronary angiography (ICA), (iv) the impact of appropriate use criteria; (v) acute chest pain, and (vi) screening of asymptomatic patients with type-2 diabetes...
May 26, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28549103/coronary-artery-disease-physiology-and-prognosis
#3
Thomas J Ford, David Corcoran, Colin Berry
No abstract text is available yet for this article.
May 26, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28549028/hybrid-coronary-revascularization-has-improved-short-term-outcomes-but-worse-mid-term-reintervention-rates-compared-to-cabg-a-propensity-matched-analysis
#4
Yu Xia, Abraham N Katz, Stephen J Forest, Robert T Pyo, Mark A Greenberg, Joseph J DeRose
OBJECTIVE: We evaluated short-term outcomes and mid-term survival and reintervention of hybrid coronary revascularization versus conventional coronary artery bypass grafting using a propensity score matched cohort. METHODS: We conducted a retrospective review of patients undergoing surgery for multivessel coronary artery disease from 2007 to 2015 at a single institution. Patients were propensity matched 1:1 to receiving hybrid coronary revascularization or conventional bypass grafting by multivariate logistic regression on preoperative characteristics...
May 25, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28549022/pictorial-review-of-surgical-anatomy-in-adult-congenital-heart-disease
#5
Carlo N De Cecco, Giuseppe Muscogiuri, José M Madrid Pérez, Marwen Eid, Pal Suranyi, Virginia W Lesslie, Gorka Bastarrika
The survival rate of patients with congenital heart disease (CHD) has dramatically improved over the last 2 decades because of technological and surgical advances in diagnosis and treatment, respectively. The vast majority of CHD patients are, in fact, amenable to treatment by either device closure or surgery. Considering the wide spectrum of surgical procedures and complex native and derived anatomy, continuous and detailed follow-up is of paramount importance. Cardiac magnetic resonance and cardiac computed tomography angiography are the cornerstones of diagnosis and follow-up of CHD, allowing for comprehensive noninvasive assessment of the heart, coronary tree, and intrathoracic great vessels, along with both morphological and functional evaluation...
May 25, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28549016/liberal-bilateral-internal-thoracic-artery-use-in-people-with-diabetes-neutralizes-the-negative-impact-of-insulin-requiring-status
#6
Giuseppe Gatti, Bernardo Benussi, Marina Bollini, Gabriella Forti, Angela Poletti, Elisabetta Rauber, Marco Gabrielli, Ariella De Monte, Gianfranco Sinagra, Aniello Pappalardo
AIMS: Bilateral internal thoracic artery (BITA) grafts are underused in insulin-dependent diabetic patients because of increased risk of postoperative complications. The impact of the insulin-requiring status on outcomes after routine BITA grafting was investigated in this retrospective study. METHODS: Skeletonized BITA grafts were used in 3228 (71.6%) of 4508 consecutive patients having multivessel coronary disease who underwent isolated coronary bypass surgery at the authors' institution from January 1999 to August 2015...
May 25, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28548975/factor-vii-activating-protease-sex-related-association-with-coronary-artery-calcification
#7
Ramshanker Ramanathan, Jørgen B Gram, Niels Peter R Sand, Bjarne L Nørgaard, Axel C P Diederichsen, Frank Vitzthum, Herbert Schwarz, Johannes J Sidelmann
: Factor VII-activating protease (FSAP) may regulate development of cardiovascular disease (CVD). We evaluated sex differences in FSAP measures and examined the association between FSAP and coronary artery calcification (CAC) in a middle-aged population. Participants were randomly selected citizens aged 50 or 60 without CVD, diabetes mellitus, Marburg I polymorphism, or hormone replacement therapy (HRT). FSAP protein concentration (total FSAP), FSAP urokinase-activating capacity (FSAP GP), and FSAP GP/total FSAP (specific FSAP activity) were measured...
May 25, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28548386/design-and-synthesis-of-atglistatin-derivatives-as-adipose-triglyceride-lipase-inhibitors
#8
Jiyu Jin, Suling Huang, Lei Wang, Ying Leng, Wei Lu
Adipose triglyceride lipase (ATGL) is a rate-limiting enzyme that mobilizes fatty acids from cellular triglyceride stores. Metabolic syndrome, which refers to a group of abnormalities that occur together and increase the risk of coronary artery disease, stroke, type-2 diabetes, and cachexia, can be treated using ATGL-specific inhibitors. Atglistatin (1) is the first small-molecule inhibitor of ATGL. In this study, we designed and synthesized 29 Atglistatin derivatives and evaluated their inhibition of forskolin-stimulated lipolysis in 3T3-L1 adipocytes as an indicator of their potential to inhibit ATGL in adipose tissues...
May 26, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28548371/the-additional-utility-of-two-dimensional-strain-in-detection-of-coronary-artery-disease-presence-and-localization-in-patients-undergoing-dobutamine-stress-echocardiogram
#9
Alaa Roushdy, Yomna Abou El Seoud, Mohamed Abd Elrahman, Basem Wadeaa, Adel Eletriby, Zainab Abd El Salam
BACKGROUND: Dobutamine stress echocardiogram (DSE) is a feasible and safe exercise-independent stress modality for diagnoses of coronary artery disease (CAD), but it is subjective, and operator dependant. Two-dimensional strain at peak stress could overcome these limitations and thus increase the accuracy of DSE. METHODS AND RESULTS: This was a prospective observational study in which 80 patients underwent DSE, two-dimensional strain at peak stress, and coronary angiography...
May 26, 2017: Echocardiography
https://www.readbyqxmd.com/read/28547666/effects-of-caffeine-intake-prior-to-stress-cardiac-magnetic-resonance-perfusion-imaging-on-regadenoson-versus-adenosine-induced-hyperemia-as-measured-by-t1-mapping
#10
R van Dijk, D Kuijpers, T A M Kaandorp, P R M van Dijkman, R Vliegenthart, P van der Harst, M Oudkerk
The antagonistic effects of caffeine on adenosine receptors are a possible cause of false-negative stress perfusion imaging. The purpose of this study was to determine the effects of coffee intake <4 h prior to stress perfusion cardiac magnetic resonance imaging (CMR) in regadenoson- versus adenosine-induced hyperemia as measured with T1-mapping. 98 consecutive patients with suspected coronary artery disease referred for either adenosine or regadenoson perfusion CMR were included in this analysis. Twenty-four patients reported coffee consumption <4 h before CMR (15 patients with adenosine, and 9 patients with regadenoson); 74 patients reported no coffee intake (50 patients with adenosine, and 24 patients with regadenoson)...
May 25, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28546762/cardiovascular-magnetic-resonance-imaging-clinical-implications-in-the-evaluation-of-connective-tissue-diseases
#11
REVIEW
Sophie Mavrogeni, George Markousis-Mavrogenis, Loukia Koutsogeorgopoulou, Genovefa Kolovou
Cardiovascular magnetic resonance imaging is a recently developed noninvasive, nonradiating, operator-independent technique that has been successfully used for the evaluation of congenital heart disease, valvular and pericardial diseases, iron overload, cardiomyopathies, great and coronary vessel diseases, cardiac inflammation, stress-rest myocardial perfusion, and fibrosis. Rheumatoid arthritis and other spondyloarthropathies, systemic lupus erythematosus, inflammatory myopathies, mixed connective tissue diseases (CTDs), systemic sclerosis, vasculitis, and sarcoidosis are among CTDs with serious cardiovascular involvement; this is due to multiple causative factors such as myopericarditis, micro/macrovascular disease, coronary artery disease, myocardial fibrosis, pulmonary hypertension, and finally heart failure...
2017: Journal of Inflammation Research
https://www.readbyqxmd.com/read/28546041/10-years-single-centre-results-of-abdominal-aortic-aneurysm-treatment-endovascular-vs-open-repair
#12
Payman Majd, Wael Ahmad, Ingrid Becker, Jan Sigge Brunkwall
OBJECTIVES: The purpose of the present study was to compare the long-term survival in matched cohorts of patients with infrarenal abdominal aortic aneurysm (AAA) undergoing an elective open repair (OR) or an endovascular aneurysm repair (EVAR). MATERIALS AND METHODS: Patients with a primary elective repair of an infrarenal aortic aneurysm between 1998 and 2006 were identified in a retrospective review of our single centre database. EVAR and OR patients were matched with respect to age, gender, renal disease, tobacco use, hypertension, chronic obstructive pulmonary disease and coronary artery disease...
May 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28546035/hybrid-metal-scaffold-jacket-versus-full-metal-jackets-in-left-anterior-descending-coronary-artery-diffuse-disease-differences-in-radiation-exposure-and-fluoroscopic-procedural-times
#13
Gianluca Rigatelli, Marco Zuin, Jacopo Frigato, Fabio Dell'Avvocata, Federico Ronco, Alberto Mazza, Laura Oliva, Dario Adami, Emiliano Bedendo, Panin Stefano
BACKGROUND/PURPOSE: Bioabsorbable vascular scaffolds (BVS) are made from a radiolucent material. Their multiple implantations on a single long diffused segment requires a specific technique with imaging magnification, which could cause an increase in dose delivered during percutaneous coronary intervention (PCI) procedure. We aimed to identify differences in radiation dose, fluoroscopy and procedural times in Hybrid DES+ multiple BVS (Absorb, Abbott Inc., USA) implantation (hybrid metal/scaffold jacket) versus multiple III generation Drug-eluting stents (DES) (full-metal jacket) in patients with long and diffuse coronary artery disease of the left anterior descending (LAD) coronary artery...
May 18, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28546033/long-term-follow-up-of-first-generation-versus-new-generation-drug-eluting-stents-in-three-vessel-coronary-artery-disease
#14
Toru Yoshizaki, Toru Naganuma, Tsuyoshi Kobayashi, Takeo Horikoshi, Hirokazu Onishi, Hiroyoshi Kawamoto, Shotaro Nakamura, Sunao Nakamura
BACKGROUNDS: Few reports have primarily focused on long-term clinical outcomes in three-vessel disease when patients were treated with either first- or new-generation drug-eluting stents (DES). The purpose of this study was to investigate different clinical outcomes after percutaneous coronary intervention (PCI) for three-vessel disease with first- or new-generation DES. METHODS: Between January 2007 and December 2013, a total of 200 patients who received complete revascularization of three-vessel disease with either first-generation DES (n=85) or new-generation DES (n=115) were analyzed in this retrospective study...
April 21, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28545849/difference-in-clinical-presentations-and-related-angiographic-findings-among-early-late-and-very-late-sirolimus-eluting-stent-failures-requiring-target-lesion-revascularization
#15
Shunsuke Kubo, Masanobu Ohya, Akimune Kuwayama, Takenobu Shimada, Katsuya Miura, Hidewo Amano, Yusuke Hyodo, Suguru Otsuru, Seiji Habara, Takeshi Tada, Hiroyuki Tanaka, Yasushi Fuku, Tsuyoshi Goto, Kazushige Kadota
BACKGROUNDS: The difference in clinical presentations (acute coronary syndrome [ACS] and stable coronary artery disease [SCAD]) and related angiographic morphologies of sirolimus-eluting stent (SES) failure requiring target lesion revascularization (TLR) during early-term (<1year), late-term (1-5years), and very late-term periods (>5years) remains unknown. METHODS: Among 4484 lesions undergoing SES implantation, clinically-driven TLR was performed on 105 lesions during early-term, 169 lesions during late-term, and 147 lesions during very late-term period...
May 13, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28545843/diabetes-and-lifetime-risk-of-coronary-heart-disease
#16
Tanvir Chowdhury Turin, Tomonori Okamura, Nahid Rumana, Arfan Raheen Afzal, Makoto Watanabe, Aya Higashiyama, Yoko M Nakao, Michikazu Nakai, Misa Takegami, Kunihiro Nishimura, Yoshihiro Kokubo, Akira Okayama, Yoshihiro Miyamoto
INTRODUCTION: Epidemiological estimate lifetime risk (LTR) is a measure that expresses the probability of disease in the remaining lifetime for individuals of a specific index age. These estimates can be useful for general audience targeted knowledge translation activities against diabetes. There are only a few reports on lifetime of impact of diabetes on coronary heart disease (CHD) events. METHODS: The Suita Study, a cohort study of cardiovascular diseases (CVD), was established in 1989...
May 22, 2017: Primary Care Diabetes
https://www.readbyqxmd.com/read/28545628/comparison-of-the-appropriateness-of-myocardial-perfusion-imaging-in-men-versus-women
#17
Ali Alsamarah, Asha Bansari, Hesham Nasser, Wajiha Raza, Issa Alsamarah, Anastasiya Bagrova, David E Winchester
After a decade of appropriate use criteria publication, the degree and predictors of inappropriate use in women compared with men are not known. We conducted a retrospective cohort investigation comparing appropriateness categories (appropriate, maybe appropriate, and rarely appropriate) and cardiovascular outcomes in patients undergoing nuclear myocardial perfusion imaging (MPI) between June 2011 and September 2014 in predominantly inpatient setting. Of 1,475 cases reviewed, 747 (50.6%) were women, and they were more likely to have rarely appropriate use 118 (15...
April 27, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28545592/impact-of-prosthesis-patient-mismatch-on-short-term-outcomes-after-aortic-valve-replacement-a-retrospective-analysis-in-east-china
#18
Lei Guo, Junnan Zheng, Liangwei Chen, Renyuan Li, Liang Ma, Yiming Ni, Haige Zhao
BACKGROUND: Prosthesis-patient mismatch (PPM) may affect the clinical outcomes of patients undergoing aortic valve replacement (AVR). We aimed to determine the incidence of PPM, its effect on short-term mortality, and the factors contributing to PPM in China. METHODS: We retrospectively examined all consecutive patients with isolated or concomitant AVR at our hospital between January 1, 2013 and December 31, 2015. PPM was defined as an effective orifice area index (EOAi) of ≤ 0...
May 25, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28545542/recognition-and-treatment-of-sleep-disordered-breathing-an-important-component-of-chronic-disease-management
#19
REVIEW
Peter C Farrell, Glenn Richards
Sleep-disordered breathing (SDB) is a highly prevalent condition, and is associated with many debilitating chronic diseases. The role of untreated obstructive sleep apnea (OSA) in arterial hypertension has been recognized in international guidelines. Treatment with continuous positive airway pressure (CPAP) is associated with clinically-relevant reductions in blood pressure. In heart failure (HF), SDB is associated with worse prognosis and increased mortality. Major HF guidelines recommend that patients should be treated for sleep apnea to improve their HF status...
May 25, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28545441/association-between-antibodies-to-carbamylated-proteins-and-subclinical-atherosclerosis-in-rheumatoid-arthritis-patients
#20
Francesca Romana Spinelli, Arbi Pecani, Francesco Ciciarello, Tania Colasanti, Manuela Di Franco, Francesca Miranda, Fabrizio Conti, Guido Valesini, Cristiano Alessandri
BACKGROUND: Rheumatoid arthritis (RA) patients carry a high risk of cardiovascular morbidity and mortality. The excess of cardiovascular disease cannot be entirely explained by traditional risk factors and the immune system contributes to the development of atherosclerosis. Moreover, post-translational modifications such as citrullination and carbamylation have been linked to inflammation and atherosclerosis. Anti-carbamylated proteins antibodies (anti-CarP) are a new subset of autoantibodies identified in RA patients...
May 25, 2017: BMC Musculoskeletal Disorders
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