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Noise. Hearing loss. Noise exposure.

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https://www.readbyqxmd.com/read/28087419/cochlear-synaptopathy-in-acquired-sensorineural-hearing-loss-manifestations-and-mechanisms
#1
REVIEW
M Charles Liberman, Sharon G Kujawa
Common causes of hearing loss in humans - exposure to loud noise or ototoxic drugs and aging - often damage sensory hair cells, reflected as elevated thresholds on the clinical audiogram. Recent studies in animal models suggest, however, that well before this overt hearing loss can be seen, a more insidious, but likely more common, process is taking place that permanently interrupts synaptic communication between sensory inner hair cells and subsets of cochlear nerve fibers. The silencing of affected neurons alters auditory information processing, whether accompanied by threshold elevations or not, and is a likely contributor to a variety of perceptual abnormalities, including speech-in-noise difficulties, tinnitus and hyperacusis...
January 10, 2017: Hearing Research
https://www.readbyqxmd.com/read/28077280/engineering-out-the-noise
#2
Kurt Yankaskas, Raymond Fischer, Jesse Spence, Jeff Komrower
The US Navy, through an Office of Naval Research (ONR) lead effort on Noise Induced Hearing Loss (NIHL), is investigating methods and techniques to mitigate hearing loss for the crews and warfighters. Hearing protection is a viable and increasingly popular method of reducing hearing exposure for many ship crewmembers; however, it has limitations on comfort and low frequency effectiveness. Furthermore, Personal Hearing Protection (PHP) is often used improperly. Proper vessel planning, programmatic changes and advances in noise control engineering can also have significant impacts by inherently reducing noise exposure through ship design and use of noise control treatments...
January 7, 2017: Hearing Research
https://www.readbyqxmd.com/read/28056268/-investigation-into-the-relationship-between-mitochondrial-12-s-rrna-gene-trna-gene-and-cytochrome-oxidase-%C3%A2-gene-variations-and-the-risk-of-noise-induced-hearing-loss
#3
J Jiao, G Z Gu, G S Chen, Y H Li, H L Zhang, Q Y Yang, X R Xu, W H Zhou, H Wu, L H He, Y X Zheng, S F Yu
Objective: To explore the relationship between mitochondrial 12 S rRNA gene variation, tRNA gene variation and cytochrome oxidase Ⅱ gene point mutations and the risk of noise-induced hearing loss (NIHL). Methods: A nested case-control study was performed that followed a cohort of 7 445 noise-exposed workers in a steel factory in Henan province, China, from January 1, 2006 to December 31, 2015. Subjects whose average hearing threshold was more than 40 dB(A) in high frequency were defined as the case group, and subjects whose average hearing threshold was less than 35 dB(A) in high frequency and less than 25 dB (A) in speech frequency were defined as the control group...
January 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28056267/-association-between-eye-absent-homolog-4-gene-polymorphisms-and-occupational-noise-induced-hearing-loss
#4
Q Y Yang, X R Xu, J Jiao, Y X Zheng, L H He, S F Yu, G Z Gu, G S Chen, W H Zhou, H Wu, Y H Li, H L Zhang, Z R Zhang
Objective: To identify the association between genetic polymorphisms in the eye absent homolog 4 (EYA4) gene and noise-induced hearing loss (NIHL). Method: A nested case control study was conducted based on a cohort of noise-exposed subjects. In total, 292 cases were selected from a steel factory from 6 297 subjects during Jan 1, 2006 to Dec 12, 2015,who had an average hearing threshold of more than 40 dB(A); 584 matched control subjects for each case were designated on the basis of matched criteria including same gender, age (±5 years) and duration of exposure to noise (±2 years)...
January 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28056266/-association-between-variations-in-protocadherin-15-gene-and-occupational-noise-induced-hearing-loss
#5
X R Xu, Q Y Yang, J Jiao, Y X Zheng, L H He, S F Yu, G Z Gu, G S Chen, W H Zhou, H Wu, Y H Li, H L Zhang, Z R Zhang
Objective: The aim of this study was to investigate whether genetic variability in the protocadherin 15 (PCDH15) gene may correspond with increased susceptibility to noise-induced hearing loss (NIHL) in a Chinese population. Methods: A nested case-control study was performed that followed a cohort of 7 445 noise-exposed workers in a steel factory of Henan province in China from January 1, 2006 to December 31, 2015. In this study, 394 cases who had an average hearing threshold of more than 40 dB (A) in high frequency were defined as the case group, and 721 controls who had an average hearing threshold of less than 35 dB (A) in high frequency and less than 25 dB (A) in speech frequency were defined as the control group...
January 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28056265/-a-cohort-study-on-occupational-noise-induced-hearing-loss-in-workers-at-an-iron-and-steel-plant
#6
S F Yu, G S Chen, J Jiao, G Z Gu, H L Zhang, X M Wang, W H Zhou, H Wu, Y H Li, Y X Zheng
Objective: To analyze the incidence rate of occupational noise-induced hearing loss in noise-exposed workers in an iron and steel plant from 2006 to 2015. Methods: Using a cohort study method, workers exposed to occupational noise from Jan 1, 2006 to Dec 12, 2015 were followed up and the pure tone hearing test was conducted. In total, 6 297 subjects completed two or more physical checks and the pure tone hearing test and were included in the analysis. The noise exposure level at the workplace and the equivalent continuous A-weighted sound pressure level for workers was monitored and the cumulative noise exposure dose was evaluated...
January 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28056138/economic-impact-of-hearing-loss-and-reduction-of-noise-induced-hearing-loss-in-the-united-states
#7
Richard L Neitzel, Tracy K Swinburn, Monica S Hammer, Daniel Eisenberg
Purpose: Hearing loss (HL) is pervasive and debilitating, and noise-induced HL is preventable by reducing environmental noise. Lack of economic analyses of HL impacts means that prevention and treatment remain a low priority for public health and environmental investment. Method: This article estimates the costs of HL on productivity by building on established estimates for HL prevalence and wage and employment differentials between those with and without HL. Results: We estimate that HL affects more than 13% of the working population...
January 1, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28054909/noise-exposure-questionnaire-a-tool-for-quantifying-annual-noise-exposure
#8
Tiffany A Johnson, Susan Cooper, Greta C Stamper, Mark Chertoff
BACKGROUND: Exposure to both occupational and nonoccupational noise is recognized as a risk factor for noise-induced hearing loss (NIHL). Although audiologists routinely inquire regarding history of noise exposure, there are limited tools available for quantifying this history or for identifying those individuals who are at highest risk for NIHL. Identifying those at highest risk would allow hearing conservation activities to be focused on those individuals. PURPOSE: To develop a detailed, task-based questionnaire for quantifying an individual's annual noise exposure (ANE) arising from both occupational and nonoccupational sources (aim 1) and to develop a short screening tool that could be used to identify individuals at high risk of NIHL (aim 2)...
January 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28054908/binaural-interference-and-the-effects-of-age-and-hearing-loss
#9
Bruna S S Mussoi, Ruth A Bentler
BACKGROUND: The existence of binaural interference, defined here as poorer speech recognition with both ears than with the better ear alone, is well documented. Studies have suggested that its prevalence may be higher in the elderly population. However, no study to date has explored binaural interference in groups of younger and older adults in conditions that favor binaural processing (i.e., in spatially separated noise). Also, the effects of hearing loss have not been studied. PURPOSE: To examine binaural interference through speech perception tests, in groups of younger adults with normal hearing, older adults with normal hearing for their age, and older adults with hearing loss...
January 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28045920/alterations-in-evoked-otoacoustic-emissions-by-the-use-of-meglumine-antimoniate-in-american-tegumentary-leishmaniasis-patients
#10
Débora Cristina de Oliveira Bezerra, Renata Oliveira de Barcelos, Ellen Carvalho de Castro, Claudia Cristina Jardim Duarte, Raquel de Vasconcellos Carvalhaes Oliveira, Tania Salgado de Sousa Torraca, Maria Helena de Araújo-Melo, Frederico Pereira Bom Braga, Benivaldo Ramos Ferreira Terceiro, Lúcia Regina do Nascimento Brahim Paes, Armando de Oliveira Schubach, Cláudia Maria Valete-Rosalino
INTRODUCTION: Tegumentary Leishmaniasis (TL) is a neglected, non-contagious, infectious disease, caused by different protozoa species of the Leishmania genus that affects skin and mucous membranes. Meglumine Antimoniate (MA), the first drug of choice for TL treatment in Brazil, has already been associated with cochlear toxicity, which is defined as damages of the cochlea caused by exposure to chemical substances, resulting in reversible or irreversible hearing loss. Auditory monitoring for cochlear toxicity aims at the early detection of auditory disorders, enabling, when possible, hearing to be preserved or an early auditory rehabilitation...
2017: PloS One
https://www.readbyqxmd.com/read/28045804/prevalence-of-hazardous-occupational-noise-exposure-hearing-loss-and-hearing-protection-usage-among-a-representative-sample-of-working-canadians
#11
Katya Feder, David Michaud, James McNamee, Elizabeth Fitzpatrick, Hugh Davies, Tony Leroux
OBJECTIVE: The aim of this study was to estimate the prevalence of hearing loss (HL), self-reported occupational noise exposure, and hearing protection usage among Canadians. METHODS: In-person household interviews were conducted with 3666 participants, aged 16 to 79 years (1811 males) with 94% completing audiometry and distortion-product otoacoustic emission (DPOAE) evaluations. Occupational noise exposure was defined as hazardous when communicating with coworkers at an arm's length distance required speaking in a raised voice...
January 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28034618/adenosine-receptors-regulate-susceptibility-to-noise-induced-neural-injury-in-the-mouse-cochlea-and-hearing-loss
#12
Srdjan M Vlajkovic, Kaushi Ambepitiya, Meagan Barclay, Detlev Boison, Gary D Housley, Peter R Thorne
Our previous studies have shown that the stimulation of A1 adenosine receptors in the inner ear can mitigate the loss of sensory hair cells and hearing loss caused by exposure to traumatic noise. Here, we focus on the role of adenosine receptors (AR) in the development of noise-induced neural injury in the cochlea using A1AR and A2AAR null mice (A1AR(-/-) and A2AAR(-/-)). Wildtype (WT) and AR deficient mice were exposed to octave band noise (8-16 kHz, 100 dB SPL) for 2 hours to induce cochlear injury and hearing loss...
December 26, 2016: Hearing Research
https://www.readbyqxmd.com/read/28030613/the-effects-of-earphone-use-and-environmental-lead-exposure-on-hearing-loss-in-the-korean-population-data-analysis-of-the-korea-national-health-and-nutrition-examination-survey-knhanes-2010-2013
#13
Da-An Huh, Yun-Hee Choi, Kyong Whan Moon
BACKGROUND: Although previous studies have reported that frequent earphone use and lead exposure are risk factors for hearing loss, most of these studies were limited to small populations or animal experiments. Several studies that presented the joint effect of combined exposure of noise and heavy metal on hearing loss were also mainly conducted on occupational workers exposed to high concentration. OBJECTIVES: We investigated both the individual and joint effects of earphone use and environmental lead exposure on hearing loss in the Korean general population...
2016: PloS One
https://www.readbyqxmd.com/read/28024462/predicting-the-perceptual-consequences-of-hidden-hearing-loss
#14
Andrew J Oxenham
Recent physiological studies in several rodent species have revealed that permanent damage can occur to the auditory system after exposure to a noise that produces only a temporary shift in absolute thresholds. The damage has been found to occur in the synapses between the cochlea's inner hair cells and the auditory nerve, effectively severing part of the connection between the ear and the brain. This synaptopathy has been termed hidden hearing loss because its effects are not thought to be revealed in standard clinical, behavioral, or physiological measures of absolute threshold...
January 2016: Trends in Hearing
https://www.readbyqxmd.com/read/28008392/assessing-the-effect-of-simultaneous-exposure-to-noise-and-cigarette-smoke-on-workers-blood-pressure
#15
Farzane Rahimpour, Ehsan Rafiei Manesh, Lida Jarahi, Saba Eghbali
INTRODUCTION: Noise, as the most common pollutant in the industrial environment, can lead to hearing loss and negatively affect other organs such as the cardiovascular system. Cigarette smoking is a popular habit among some workers, and can also have a negative effect on the cardiovascular system. This study was aimed to investigate the effect of simultaneous exposure to noise and cigarette smoke on the blood pressure of workers at a manufacturing factory. MATERIALS AND METHODS: This cross-sectional study enrolled 604 workers at a steel factory...
November 2016: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28007648/minocycline-attenuates-noise-induced-hearing-loss-in-rats
#16
Jing Zhang, Yong-Li Song, Ke-Yong Tian, Jian-Hua Qiu
Noise-induced hearing loss (NIHL) is a serious health concern and prevention of hair cell death or therapeutic intervention at the early stage of NIHL is critical to preserve hearing. Minocycline is a semi-synthetic derivative of tetracycline and has been shown to have otoprotective effects in ototoxic drug-induced hearing impairment, however, whether minocycline can protect against NIHL has not been investigated. The present study demonstrated elevated ABR (auditory brainstem response) thresholds and outer hair cell loss following traumatic noise exposure, which was mitigated by intraperitoneal administration of minocycline (45mg/kg/d) for 5 consecutive days...
December 19, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/28007526/noise-induced-cochlear-synaptopathy-past-findings-and-future-studies
#17
REVIEW
Megan Kobel, Colleen G Le Prell, Jennifer Liu, John W Hawks, Jianxin Bao
For decades, we have presumed the death of hair cells and spiral ganglion neurons are the main cause of hearing loss and difficulties understanding speech in noise, but new findings suggest synapse loss may be the key contributor. Specifically, recent preclinical studies suggest that the synapses between inner hair cells and spiral ganglion neurons with low spontaneous rates and high thresholds are the most vulnerable subcellular structures, with respect to insults during aging and noise exposure. This cochlear synaptopathy can be "hidden" because this synaptic loss can occur without permanent hearing threshold shifts...
December 19, 2016: Hearing Research
https://www.readbyqxmd.com/read/28003148/evidence-of-hidden-hearing-loss-following-noise-exposures-that-produce-robust-tts-and-abr-wave-i-amplitude-reductions
#18
Edward Lobarinas, Christopher Spankovich, Colleen G Le Prell
In animals, noise exposures that produce robust temporary threshold shifts (TTS) can produce immediate damage to afferent synapses and long-term degeneration of low spontaneous rate auditory nerve fibers. This synaptopathic damage has been shown to correlate with reduced auditory brainstem response (ABR) wave-I amplitudes at suprathreshold levels. The perceptual consequences of this "synaptopathy" remain unknown but have been suggested to include compromised hearing performance in competing background noise...
December 19, 2016: Hearing Research
https://www.readbyqxmd.com/read/28002082/long-term-synergistic-interaction-of-cisplatin-and-noise-induced-hearing-losses
#19
J Riley DeBacker, Ryan T Harrison, Eric C Bielefeld
OBJECTIVE: Past experiments in the literature have shown that cisplatin interacts synergistically with noise to create hearing loss. Much of the previous work on the synergistic interaction of noise and cisplatin tested exposures that occurred very close together in time. The present study assessed whether rats that have been exposed to cisplatin continue to show increased susceptibility to noise-induced hearing loss months after conclusion of the cisplatin exposure. DESIGN: Thirty-two Fischer 344/NHsd rats were exposed to one of five conditions: (1) cisplatin exposure followed by immediate cochlear tissue harvest, (2) cisplatin exposure and a 20-week monitoring period before tissue harvest, (3) cisplatin exposure followed immediately by noise exposure, (4) cisplatin exposure followed by noise exposure 16 weeks later, and (5) noise exposure without cisplatin exposure...
December 19, 2016: Ear and Hearing
https://www.readbyqxmd.com/read/27991471/cigarette-and-snus-modified-association-between-unprotected-exposure-to-noise-from-hunting-rifle-caliber-weapons-and-high-frequency-hearing-loss-a-cross-sectional-study-among-swedish-hunters
#20
Louise Honeth, Peter Ström, Alexander Ploner, Dan Bagger-Sjöbäck, Ulf Rosenhall, Olof Nyrén
AIM: To investigate in this cross-sectional study among Swedish hunters if tobacco use modifies the previously observed association, expressed as prevalence ratio (PR), between unprotected exposure to impulse noise from hunting rifle caliber (HRC) weapons and high-frequency hearing impairment (HFHI). SETTINGS AND DESIGN: A nationwide cross-sectional epidemiologic study was conducted among Swedish sport hunters in 2012. MATERIALS AND METHODS: The study was Internet-based and consisted of a questionnaire and an Internet-based audiometry test...
November 2016: Noise & Health
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