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Noise. Hearing loss. Noise exposure.

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https://www.readbyqxmd.com/read/28432353/severe-hearing-loss-and-outer-hair-cell-death-in-homozygous-foxo3-knockout-mice-after-moderate-noise-exposure
#1
Felicia Gilels, Stephen T Paquette, Holly J Beaulac, Anwen Bullen, Patricia M White
Noise induced hearing loss (NIHL) is a disease that affects millions of Americans. Identifying genetic pathways that influence recovery from noise exposure is an important step forward in understanding NIHL. The transcription factor Foxo3 integrates the cellular response to oxidative stress and plays a role in extending lifespan in many organisms, including humans. Here we show that Foxo3 is required for auditory function after noise exposure in a mouse model system, measured by ABR. Absent Foxo3, outer hair cells are lost throughout the middle and higher frequencies...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28422030/analysis-of-hearing-and-tinnitus-in-workers-exposed-to-occupational-noise
#2
Marlene Escher Boger, André Luiz Lopes Sampaio, Carlos Augusto Costa Pires de Oliveira
INTRODUCTION: Noise is one of the harmful agents to health that is present in the various branches of economic activity. Hearing loss and tinnitus are among the most frequently reported complaints by workers exposed to occupational noise. OBJECTIVE: To analyze the hearing and tinnitus in normal-hearing workers exposed to occupational noise. METHODS: This is a cross-sectional analytical trial in metallurgical industries, in which we evaluated normal-hearing workers through anamnesis, audiometry and otoacoustic emissions...
April 19, 2017: International Tinnitus Journal
https://www.readbyqxmd.com/read/28420925/effect-of-smoking-on-hearing-loss-in-refractory-s-factory-male-worker-with-occupational-noise-exposure-in-iran
#3
Mohammadreza Mofateh, Qasim Karimi, Mohammad Hamed Hosseini, Gholam Reza Sharif-Zadeh
OBJECTIVE: To assess the effect of smoking on hearing loss in factory workers with occupational noise exposure. METHODS: This cross-sectional study was conducted at Birjand University of Medical Sciences, Birjand, Iran, from May to July 2013, and comprised smoking and non-smoking factory male workers. All of them were exposed to occupational noise level more than 85 decibels for at least 10 years. All participants underwent audiometric testing. SPSS 15 was used for data analysis...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28372082/big-brown-bats-eptesicus-fuscus-maintain-hearing-sensitivity-after-exposure-to-intense-band-limited-noise
#4
Andrea Megela Simmons, Kelsey N Hom, James A Simmons
Thresholds to short-duration narrowband frequency-modulated (FM) sweeps were measured in six big brown bats (Eptesicus fuscus) in a two-alternative forced choice passive listening task before and after exposure to band-limited noise (lower and upper frequencies between 10 and 50 kHz, 1 h, 116-119 dB sound pressure level root mean square; sound exposure level 152 dB). At recovery time points of 2 and 5 min post-exposure, thresholds varied from -4 to +4 dB from pre-exposure threshold estimates. Thresholds after sham (control) exposures varied from -6 to +2 dB from pre-exposure estimates...
March 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28366808/calpain-inhibitor-alleviates-permanent-hearing-loss-induced-by-intense-noise-by-preventing-disruption-of-gap-junction-mediated-intercellular-communication-in-the-cochlear-spiral-ligament
#5
Taro Yamaguchi, Masanori Yoneyama, Kiyokazu Ogita
Our previous studies demonstrated that intense noise-induced hearing loss might be at least in part due to an oxidative stress-induced decrease in the level of gap junction-composing protein connexins in the spiral ligament (SL) of the cochlear lateral wall structures in mice. Further, an in vivo exposure of mice to intense noise activates calpain in the cochlear SL. Based on these studies, we sought to determine whether a calpain inhibitor would prevent an intense noise exposure from causing hearing loss, disruption of gap junction-mediated intercellular communication (GJIC) in the SL...
May 15, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28292353/the-effect-of-pcdh15-gene-variations-on-the-risk-of-noise-induced-hearing-loss-in-a-chinese-population
#6
Xiang Rong Xu, Jing Jing Wang, Qiu Yue Yang, Jie Jiao, Li Hua He, Shan Fa Yu, Gui Zhen Gu, Guo Shun Chen, Wen Hui Zhou, Hui Wu, Yan Hong Li, Huan Ling Zhang, Zeng Rui Zhang, Xian Ning Jin
Noise-induced hearing loss (NIHL) is a complex disease caused by interactions between environmental and genetic factors. This study investigated whether genetic variability in protocadherin related 15 (PCDH15) underlies an increased susceptibility to the development of NIHL in a Chinese population. The results showed that compared with the TT genotype of rs11004085, CT/CC genotypes were associated with an increased risk of NIHL [adjusted odds ratio (OR) = 2.64; 95% confidence interval (CI): 1.14-6.11, P = 0...
February 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28286364/considerations-in-the-development-of-a-sound-tolerance-interview-and-questionnaire-instrument
#7
REVIEW
LaGuinn P Sherlock, Craig Formby
Most clinicians approach the objective fitting of hearing aids with three goals in mind: audibility, comfort, and tolerance. When these three amplification goals have been met, the hearing aid user is more likely to adapt to and perceive benefit from hearing aid use. However, problems related to the loudness of sounds and reduced sound tolerance, which may or may not be reported by the aided user, can adversely impact adaptation to amplification and the individual's quality of life. Although there are several standardized questionnaires available to evaluate hearing aid benefit and satisfaction, there is no standardized questionnaire or interview tool for evaluating reduced sound tolerance and the related impact on hearing aid use...
February 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28280462/the-role-of-glia-in-the-peripheral-and-central-auditory-system-following-noise-overexposure-contribution-of-tnf-%C3%AE-and-il-1%C3%AE-to-the-pathogenesis-of-hearing-loss
#8
Verónica Fuentes-Santamaría, Juan Carlos Alvarado, Pedro Melgar-Rojas, María C Gabaldón-Ull, Josef M Miller, José M Juiz
Repeated noise exposure induces inflammation and cellular adaptations in the peripheral and central auditory system resulting in pathophysiology of hearing loss. In this study, we analyzed the mechanisms by which noise-induced inflammatory-related events in the cochlea activate glial-mediated cellular responses in the cochlear nucleus (CN), the first relay station of the auditory pathway. The auditory function, glial activation, modifications in gene expression and protein levels of inflammatory mediators and ultrastructural changes in glial-neuronal interactions were assessed in rats exposed to broadband noise (0...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/28278069/chicago-transit-authority-train-noise-exposure
#9
Linh T Phan, Rachael M Jones
To characterize noise exposure of riders on Chicago Transit Authority (CTA) trains, we measured noise levels twice on each segment of seven of the eight CTA train lines, which are named after colors, yielding 48 time-series measurements. We found the Blue Line has the highest noise levels compared to other train lines, with mean 76.9 dBA; and that the maximum noise level, 88.9 dBA occurred in the tunnel between the Chicago and Grand stations. Train segments involving travel through a tunnel had significantly higher noise levels than segments with travel on elevated and ground level tracks...
February 7, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28260833/development-of-noise-controls-for-longwall-shearer-cutting-drums
#10
Hugo E Camargo, Amanda S Azman, Lynn Alcorn
Noise-induced hearing loss is the second most pervasive disease in the mining industry. The exposure of miners to noise levels above the permissible exposure level results in hearing loss of approximately 80% of coal miners by retirement age. In addition, between 2002 and 2011, approximately 48% of longwall shearer operators were overexposed in coal mines in the United States. Previous research identified the two rotating cutting drums used by the longwall shearer to extract coal as the most significant sound-radiating components...
September 1, 2016: Noise Control Engineering Journal
https://www.readbyqxmd.com/read/28253638/noise-exposure-among-federal-wildland-fire-fighters
#11
George Broyles, Corey R Butler, Chucri A Kardous
Wildland fire fighters use many tools and equipment that produce noise levels that may be considered hazardous to hearing. This study evaluated 174 personal dosimetry measurements on 156 wildland fire fighters conducting various training and fire suppression tasks. Noise exposures often exceeded occupational exposure limits and suggest that wildland fire fighters may be at risk of developing noise-induced hearing loss, particularly those operating chainsaws, chippers, and masticators. The authors recommend a comprehensive approach to protecting these fire fighters that includes purchasing quieter equipment, noise and administrative controls, and enrolling these fire fighters into a hearing conservation program...
February 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28241680/-current-status-of-hearing-loss-and-related-influencing-factors-in-workers-with-noise-exposure-in-refining-and-chemical-industry
#12
S S Wu, J N Yu, C H He, H X Mu, C Wang, Y Zhang, C Y Zhang, S F Yu, X L Li
Objective: To investigate the current status of hearing loss and related influencing factors in workers with noise exposure in refining and chemical industry. Methods: From August 2015 to March 2016, the investigation method of collecting the data of past occupational health examinations and measuring noise in working environment was used to enroll 8 672 male workers. Results: Of all workers, 11.6% were diagnosed with hearing loss. There were significant differences in the distribution of hearing impairment among workers exposed to noise at different ages, device types and types of work (χ(2)=17...
December 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28241676/-influencing-factors-for-hearing-loss-in-workers-exposed-to-noise-in-a-cement-plant
#13
X M Wang, H Wu, J Jiao, Y H Li, Z R Zhang, W H Zhou, S F Yu
Objective: To investigate the incidence of noise-induced hearing loss (NIHL) and related influencing factors in workers exposed to noise in a cement plant. Methods: In October 2015, cluster sampling was used for questionnaire investigation and health examination of workers exposed to noise in a cement plant in Henan Province, China. The association of demographic features, living habits, cumulative noise exposure (CNE) , hypertension, and hyperlipidemia with NIHL was analyzed. Results: There was mainly medium-or high-frequency noise in the working place of this cement plant...
December 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28241675/-association-between-single-nucleotide-polymorphismsin-human-heat-shock-protein-70-gene-and-susceptibility-to-noise-induced-hearing-loss
#14
Y H Li, G S Chen, J Jiao, W H Zhou, H Wu, G Z Gu, H L Zhang, Y X Zheng, S F Yu
Objective: To investigate the association between the single nucleotide polymorphisms (SNPs) at rs1043618, rs2075800, and rs2763979 in human heat shock protein 70 (HSP70) gene and susceptibility to noise-induced hearing loss (NIHL) . Methods: A case-control study was performed, and 5 934 workers exposed to noise in an iron and steel plant in Henan, China, who underwent physical examination from 2006 to 2015, were enrolled as study subjects. According to the criteria of binaural average high - frequency (3000, 4000, and 6000 Hz) hearing threshold≥40 dB (HL) and monauralaverage speech-frequency (500, 1000, 2000 Hz) hearing threshold≥26 dB (HL) on the basis of binauralhigh frequency loss measured by pure tone audiometry, as well as the exclusion of NIHL, a total of 286 workers were enrolled as hearing loss group; after the adjustment for sex, type of work, age (difference≤5 years) , and working years of noise exposure (difference ≤2 years) , 286 workers were enrolled as control group...
December 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28241674/-association-between-serum-magnesium-ion-level-and-risk-of-noise-induced-hearing-loss
#15
J Jiao, G Z Gu, G S Chen, Y X Zheng, H L Zhang, Q Geng, Y B Cheng, S F Yu
Objective: To investigate the association between serum magnesium ion level and risk of noise-induced hearing loss (NIHL) . Methods: Acohort study was performed for 7 445 workers exposed to noise in the steelmaking and steel rolling workshops of an iron and steel enterprise in Henan Province, China. The follow-up time was from January 1, 2006 to December 31, 2015. The workers with a binaural average high-frequency hearing threshold of ≥40 dB (HL) were enrolled as case group, and those with a binaural average high-frequency hearing threshold of <35 dB (HL) and a binaural average speech frequency of ≤25 dB (HL) were enrolled as control group...
December 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28226026/diabetes-mellitus-and-sensorineural-hearing-loss-is-there-an-association-baseline-of-the-brazilian-longitudinal-study-of-adult-health-elsa-brasil
#16
Alessandra G Samelli, Itamar S Santos, Renata R Moreira, Camila M Rabelo, Laurie P Rolim, Isabela J Bensenõr, Paulo A Lotufo
OBJECTIVES: Although several studies have investigated the effects of diabetes on hearing loss, the relationship between these two conditions remains unclear. Some studies have suggested that diabetes may cause sensorineural hearing loss, whereas others have failed to find an association. The biggest challenge in investigating the association between diabetes and hearing loss is the presence of confounding variables and the complexity of the auditory system. Our study investigated the association between diabetes and sensorineural hearing loss...
January 1, 2017: Clinics
https://www.readbyqxmd.com/read/28224282/micrornas-effective-elements-in-ear-related-diseases-and-hearing-loss
#17
REVIEW
Mohammad-Reza Mahmoudian-Sani, Ameneh Mehri-Ghahfarrokhi, Fereshteh Ahmadinejad, Morteza Hashemzadeh-Chaleshtori, Massoud Saidijam, Mohammad-Saeid Jami
miRNAs are important factors for post-transcriptional process that controls gene expression at mRNA level. Various biological processes, including growth and differentiation, are regulated by miRNAs. miRNAs have been demonstrated to play an essential role in development and progression of hearing loss. Nowadays, miRNAs are known as critical factors involved in different physiological, biological, and pathological processes, such as gene expression, progressive sensorineural hearing loss, age-related hearing loss, noise-induced hearing loss, cholesteatoma, schwannomas, and inner ear inflammation...
February 21, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28220907/exposure-to-excessive-sounds-and-hearing-status-in-academic-classical-music-students
#18
Małgorzata Pawlaczyk-Łuszczyńska, Małgorzata Zamojska-Daniszewska, Adam Dudarewicz, Kamil Zaborowski
OBJECTIVES: The aim of this study was to assess hearing of music students in relation to their exposure to excessive sounds. MATERIAL AND METHODS: Standard pure-tone audiometry (PTA) was performed in 168 music students, aged 22.5±2.5 years. The control group included 67 subjects, non-music students and non-musicians, aged 22.8±3.3 years. Data on the study subjects' musical experience, instruments in use, time of weekly practice and additional risk factors for noise-induced hearing loss (NIHL) were identified by means of a questionnaire survey...
February 21, 2017: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/28215376/hearing-related-health-among-adult-american-indians-from-a-pacific-northwest-tribe
#19
Kapuaolaokalaniakea Gellert, William Hal Martin, Jodi A Lapidus, Leslie Wosnig, Thomas M Becker
INTRODUCTION: Hearing loss and tinnitus are common in most populations, although few data have addressed hearing-related health among tribal members and the need for public health interventions. METHODS: This cross-sectional study examined prevalence and risk factors for hearing loss and tinnitus among 217 adults in a Pacific Northwest tribe. Frequency measures were conducted for difficulty hearing certain sounds and hearing aid use. In 2006, risk factors were examined for two outcomes-hearing loss and tinnitus-with analysis conducted in the same year...
March 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28214516/saturation-of-long-term-potentiation-in-the-dorsal-cochlear-nucleus-and-its-pharmacological-reversal-in-an-experimental-model-of-tinnitus
#20
Thomas Tagoe, Daniel Deeping, Martine Hamann
Animal models have demonstrated that tinnitus is a pathology of dysfunctional excitability in the central auditory system, in particular in the dorsal cochlear nucleus (DCN) of the brainstem. We used a murine model and studied whether acoustic over-exposure leading to hearing loss and tinnitus, affects long-term potentiation (LTP) at DCN multisensory synapses. Whole cell and field potential recordings were used to study the effects on release probability and synaptic plasticity, respectively in brainstem slices...
February 16, 2017: Experimental Neurology
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