Catherine Hyams, David T Arnold, Robyn Heath, Zahin Amin-Chowdhury, David Hettle, Gabriella Ruffino, Paul North, Charli Grimes, Norman K Fry, Philip Williams, Robert Challen, Leon Danon, O Martin Williams, Shamez Ladhani, Adam Finn, Nick Maskell
RATIONALE: Streptococcus pneumoniae epidemiology is changing in response to vaccination and some data suggest that empyema incidence is increasing. However, differences exist between the UK and US studies. We describe trends in the clinical phenotype of adult pneumococcal pleural infection, including simple parapneumonic effusions (SPE) in the pneumococcal conjugate vaccination (PCV) era. OBJECTIVES: To determine whether there were differences in pneumococcal disease presentation and severity associated with pleural infection...
May 2023: BMJ Open Respiratory Research