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Implant corrosion

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https://www.readbyqxmd.com/read/29772348/biosafety-stability-and-osteogenic-activity-of-novel-implants-made-of-zr-70-ni-16-cu-6-al-8-bulk-metallic-glass-for-biomedical-application
#1
Hiroto Ida, Masahiro Seiryu, Nobuo Takeshita, Masanari Iwasaki, Yoshihiko Yokoyama, Yusuke Tsutsumi, Etsuko Ikeda, Satoshi Sasaki, Shunro Miyashita, Shutaro Sasaki, Tomohiro Fukunaga, Toru Deguchi, Teruko Takano-Yamamoto
Superior mechanical and chemical properties of Zr70 Ni16 Cu6 Al8 bulk metallic glass (BMG) demonstrate its promise as a novel biomaterial for fabrication of implants. The aim of the present study was to validate mechanical, chemical, and biological properties of Zr70 Ni16 Cu6 Al8 BMG through comparison with titanium (Ti). Our data indicated higher tensile strength, lower Young's modulus, and reduced metal ion release of Zr70 Ni16 Cu6 Al8 BMG compared with Ti. Biosafety of bone marrow mesenchymal cells on Zr70 Ni16 Cu6 Al8 BMG was comparable to that of Ti...
May 14, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29763442/platinum-corrosion-products-from-electrode-contacts-of-human-cochlear-implants-induce-cell-death-in-cell-culture-models
#2
Kirsten Wissel, Gudrun Brandes, Nils Pütz, Gian Luigi Angrisani, Jan Thieleke, Thomas Lenarz, Martin Durisin
Despite the technological progress made with cochlear implants (CI), impedances and their diagnosis remain a focus of interest. Increases in impedance have been related to technical defects of the electrode as well as inflammatory and/or fibrosis along the electrode. Recent studies have demonstrated highly increased impedances as the result of corroded platinum (Pt) electrode contacts. This in vitro study examined the effects of Pt ions and compounds generated by corrosion of the electrode contacts of a human CI on cell metabolism...
2018: PloS One
https://www.readbyqxmd.com/read/29760549/nanostructured-ag-substituted-fluorhydroxyapatite-tio-2-coatings-for-enhanced-bactericidal-effects-and-osteoinductivity-of-ti-for-biomedical-applications
#3
Yong Huang, Guiqin Song, Xiaotong Chang, Zhenhui Wang, Xuejiao Zhang, Shuguang Han, Zhuobin Su, Hejie Yang, Dongdong Yang, Xiaojun Zhang
Background: Poor mechanical properties, undesirable fast dissolution rate, and lack of antibacterial activity limit the application of hydroxyapatite (HA) as an implant coating material. To overcome these limitations, a hybrid coating of Ag+ -substituted fluorhydroxyapatite and titania nanotube (TNT) was prepared. Methods: The incorporation of silver into the HA-TiO2 hybrid coating improves its antimicrobial properties. The addition of F as a second binary element increases the structural stability of the coating...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29756511/surface-integrity-of-polyethylene-liners-following-trunnionosis-of-a-dual-modular-neck-total-hip-implant
#4
Ben Gi Spiegelberg, Brent A Lanting, James L Howard, Matthew G Teeter, Douglas Dr Naudie
BACKGROUND: There has been a trend in the evolution of total hip arthroplasty towards increased modularity; with this increase in modularity come some potentially harmful consequences. Modularity at the neck shaft junction has been linked to corrosion, adverse reaction to metal debris and pseudotumour formation. AIM: The aim of this retrieval study is to assess whether the surface integrity of the polyethylene (PE) liner is affected by metal wear debris in a single implant design series of THA revised for trunnionosis...
May 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29744448/biodegradation-of-mg-14li-alloy-in-simulated-body-fluid-a-proof-of-concept-study
#5
Xiao-Bo Chen, Chuanqiang Li, Daokui Xu
High corrosion kinetics and localised corrosion progress are the primary concerns arising from the clinical implementation of magnesium (Mg) based implantable devices. In this study, a binary Mg-lithium (Li) alloy consisting a record high Li content of 14% (in weight) was employed as model material aiming to yield homogenous and slow corrosion behaviour in a simulated body fluid, i.e. minimum essential medium (MEM), in comparison to that of generic Mg alloy AZ31 and biocompatible Mg-0.5Zn-0.5Ca counterparts...
March 2018: Bioactive Materials
https://www.readbyqxmd.com/read/29744412/biodegradation-behavior-of-magnesium-and-zk60-alloy-in-artificial-urine-and-rat-models
#6
Shiying Zhang, Yanze Bi, Jianye Li, Zhenguo Wang, Jingmin Yan, Jiawang Song, Haibo Sheng, Heqing Guo, Yan Li
In this work, the biodegradable and histocompatibility properties of pure Mg and ZK60 alloy were investigated as new temporary implants for urinary applications. The corrosion mechanism in artificial urine was proposed using electrochemical impedance spectroscopy and potentiodynamic polarization tests. The corrosion potential of pure magnesium and ZK60 alloy were -1820 and -1561 mV, respectively, and the corrosion current densities were 59.66 ± 6.41 and 41.94 ± 0.53 μA cm-2 , respectively. The in vitro degradation rates for pure Mg and ZK60 alloy in artificial urine were 0...
June 2017: Bioactive Materials
https://www.readbyqxmd.com/read/29738600/adapter-sleeves-are-not-needed-to-reduce-the-risk-of-fracture-of-a-new-ceramic-head-implanted-on-a-well-fixed-stem
#7
Young-Hoo Kim, Jang-Won Park, Jun-Shik Kim
The purpose of this study was to assess (1) the prevalence of the fracture of ceramic heads implanted on used trunnions of well-fixed stems without using a titanium adapter sleeve; (2) the prevalence of trunnionosis secondary to fretting and/or corrosion at the trunnion of the well-fixed stem; and (3) clinical and radiographic results and the survival rate of the revised acetabular components. Eighty-eight patients (100 hips) underwent isolated revision of the acetabular components for polyethylene wear and osteolysis of the acetabulum...
May 8, 2018: Orthopedics
https://www.readbyqxmd.com/read/29738506/macrophage-biocompatibility-of-cocr-wear-particles-produced-under-polarization-in-hyaluronic-acid-aqueous-solution
#8
Blanca Teresa Perez-Maceda, María Encarnación López-Fernández, Iván Díaz, Aaron Kavanaugh, Fabrizio Billi, María Lorenza Escudero, María Cristina García-Alonso, Rosa María Lozano
Macrophages are the main cells involved in inflammatory processes and in the primary response to debris derived from wear of implanted CoCr alloys. The biocompatibility of wear particles from a high carbon CoCr alloy produced under polarization in hyaluronic acid (HA) aqueous solution was evaluated in J774A.1 mouse macrophages cultures. Polarization was applied to mimic the electrical interactions observed in living tissues. Wear tests were performed in a pin-on-disk tribometer integrating an electrochemical cell in phosphate buffer solution (PBS) and in PBS supplemented with 3 g/L HA, an average concentration that is generally found in synovial fluid, used as lubricant solution...
May 8, 2018: Materials
https://www.readbyqxmd.com/read/29715614/corrosion-resistance-and-antibacterial-properties-of-polysiloxane-modified-layer-by-layer-assembled-self-healing-coating-on-magnesium-alloy
#9
Yanbin Zhao, Liqian Shi, Xiaojing Ji, Jichen Li, Zhuangzhuang Han, Shuoqi Li, Rongchang Zeng, Fen Zhang, Zhenlin Wang
Magnesium (Mg) alloys have shown great potential in biomedical materials due to their biocompatibility and biodegradability. However, rapid corrosion rate, which is an inevitable obstacle, hinders their clinical applications. Besides, it is necessary to endow Mg alloys with antibacterial properties, which are crucial for temporary implants. In this study, silver nanoparticles (AgNPs) and polymethyltrimethoxysilane (PMTMS) were introduced into AZ31 Mg alloys via layer-by-layer (LbL) assembly and siloxane self-condensation reaction...
April 18, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29709241/in-vitro-and-in-vivo-studies-of-anti-bacterial-copper-bearing-titanium-alloy-for-dental-application
#10
Rui Liu, Yulong Tang, Lilan Zeng, Ying Zhao, Zheng Ma, Ziqing Sun, Liangbi Xiang, Ling Ren, Ke Yang
OBJECTIVE: A novel copper-bearing titanium alloy (Ti-Cu) was fabricated for dental application that is expected to efficiently restrain the growth of bacteria and discourage biofilm formation. The aim of this study was to investigate both the antibacterial activity and biofilm inhibition of Ti-Cu alloy in vitro, and the antibacterial effect of Ti-Cu implant in early stage of peri-implantitis in vivo. METHODS: Staphylococcus aureus and Escherichia coli were selected to evaluate the antibacterial activity of Ti-Cu alloy and Ti served as control...
April 27, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29707071/gas-formation-and-biological-effects-of-biodegradable-magnesium-in-a-preclinical-and-clinical-observation
#11
Yu-Kyoung Kim, Kwang-Bok Lee, Seo-Young Kim, Ken Bode, Yong-Seok Jang, Tae-Young Kwon, Moo Heon Jeon, Min-Ho Lee
Magnesium alloys are biodegradable metals receiving increasing attention, but the clinical applications of these materials are delayed by concerns over the rapid corrosion rate and gas formation. Unlike corrosion, which weakens mechanical properties, the gas formation issue has received little attention. Therefore, we evaluated the gas formation and biological effects for Mg implants through preclinical (immersed in Earle's balanced salt solution and in vivo ) and clinical studies. The immersion test examined the gas volume and composition...
2018: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/29705684/what-factors-drive-taper-corrosion
#12
Robin Pourzal, Hannah J Lundberg, Deborah J Hall, Joshua J Jacobs
Adverse local tissue reactions to corrosion products can lead to total hip arthroplasty failure. Although this problem has been well known for more than 25 years, it has seemingly increased in frequency over the recent years. The occurrence of corrosion is multifactorial-depending on implant, patient, and surgeon factors. As of now, there is no "one-size-fits-all" solution to prevent corrosion in total hip arthroplasty devices. Thus, it is imperative to fully understand the exact mechanisms of modular junction corrosion to prevent premature implant failure...
March 30, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29700340/a-unique-hybrid-structured-surface-produced-by-rapid-electrochemical-anodization-enhances-bio-corrosion-resistance-and-bone-cell-responses-of-%C3%AE-type-ti-24nb-4zr-8sn-alloy
#13
Chia-Fei Liu, Tzu-Hsin Lee, Jeng-Fen Liu, Wen-Tao Hou, Shu-Jun Li, Yu-Lin Hao, Haobo Pan, Her-Hsiung Huang
Ti-24Nb-4Zr-8Sn (Ti2448), a new β-type Ti alloy, consists of nontoxic elements and exhibits a low uniaxial tensile elastic modulus of approximately 45 GPa for biomedical implant applications. Nevertheless, the bio-corrosion resistance and biocompatibility of Ti2448 alloys must be improved for long-term clinical use. In this study, a rapid electrochemical anodization treatment was used on Ti2448 alloys to enhance the bio-corrosion resistance and bone cell responses by altering the surface characteristics...
April 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29691164/the-fate-of-elevated-metal-ion-levels-after-revision-surgery-for-head-neck-taper-corrosion-in-patients-with-metal-on-polyethylene-total-hip-arthroplasty
#14
Young-Min Kwon, John MacAuliffe, Yun Peng, Paul Arauz
BACKGROUND: Elevated metal ion levels have been associated with the presence of adverse local tissue reactions in patients with metal-on-polyethylene (MoP) total hip arthroplasty (THA) secondary to corrosion at head-neck taper junction. Patients are frequently concerned with their elevated systemic metal ion levels. This study investigated the rate of decline of serum cobalt and chromium ion levels after revision surgery. METHODS: A total of 39 patients with MoP THA were revised because of the presence of symptomatic adverse local tissue reactions on magnetic resonance imaging with elevated serum metal ion levels...
March 30, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29649639/cobalt-ii-ions-and-nanoparticles-induce-macrophage-retention-by-ros-mediated-down-regulation-of-rhoa-expression
#15
Jing Xu, Junyao Yang, Agata Nyga, Mazdak Ehteramyan, Ana Moraga, Yuanhao Wu, Lingfang Zeng, Martin M Knight, Julia C Shelton
Histological assessments of synovial tissues from patients with failed CoCr alloy hip prostheses demonstrate extensive infiltration and accumulation of macrophages, often loaded with large quantities of particulate debris. The resulting adverse reaction to metal debris (ARMD) frequently leads to early joint revision. Inflammatory response starts with the recruitment of immune cells and requires the egress of macrophages from the inflamed site for resolution of the reaction. Metal ions (Co2+ and Cr3+ ) have been shown to stimulate the migration of T lymphocytes but their effects on macrophages motility are still poorly understood...
April 9, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29623422/the-role-of-citrate-lactate-and-transferrin-in-determining-titanium-release-from-surgical-devices-into-human-serum
#16
Justin P Curtin, Minji Wang, Tianfan Cheng, Lijian Jin, Hongzhe Sun
The presence of ionic titanium in the serum of patients with titanium implants is currently unexplained. This is presumed due to corrosion, and yet the serum titanium concentration measured in patients is far greater than that predicted by its solubility. The binding of titanium ion as Ti(IV) to human transferrin (hTF) in serum indicates that Ti(IV) ions interact with human physiology. This is an intriguing finding since there is currently no known role for titanium ions in human physiology. Thus, understanding the factors that determine in vivo titanium ion release is relevant to further understanding this metal's interactions with human biochemistry...
April 5, 2018: Journal of Biological Inorganic Chemistry: JBIC
https://www.readbyqxmd.com/read/29618341/quantitative-analysis-of-near-implant-magnesium-accumulation-for-a-si-containing-coated-az31-cage-from-a-goat-cervical-spine-fusion-model
#17
Fan Zhang, Haocheng Xu, Hongli Wang, Fang Geng, Xiaosheng Ma, Minghao Shao, Shun Xu, Feizhou Lu, Jianyuan Jiang
BACKGROUND: Magnesium (Mg) released from Mg-based implants degradation is believed to be effective in improving osteogenesis, however, studies focusing on Mg-based interbody cages are limited and fusion success was never reported. As excessive Mg accumulation can inhibit new bone formation, this study is designed to explain the possible reasons for the fusion failure of Mg-based cages by analyzing the relationships between the intervertebral Mg accumulation and the resulting interbody fusion...
April 4, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29614014/electrochemical-impedance-and-polarization-corrosion-studies-of-tantalum-surface-modified-by-dc-plasma-electrolytic-oxidation
#18
Maciej Sowa, Wojciech Simka
Tantalum has recently become an actively researched biomaterial for the bone reconstruction applications because of its excellent corrosion resistance and successful clinical records. However, a bare Ta surface is not capable of directly bonding to the bone upon implantation and requires some method of bioactivation. In this study, this was realized by direct current (DC) plasma electrolytic oxidation (PEO). Susceptibility to corrosion is a major factor determining the service-life of an implant. Therefore, herein, the corrosion resistance of the PEO coatings on Ta was investigated in Ringer's solution...
April 3, 2018: Materials
https://www.readbyqxmd.com/read/29607729/in-vitro-and-in-vivo-assessment-of-biomedical-mg-ca-alloys-for-bone-implant-applications
#19
Preeti Makkar, Swapan Kumar Sarkar, Andrew R Padalhin, Byoung-Gi Moon, Young Seon Lee, Byong Taek Lee
BACKGROUND: Magnesium (Mg)-based alloys are considered to be promising materials for implant application due to their excellent biocompatibility, biodegradability, and mechanical properties close to bone. However, low corrosion resistance and fast degradation are limiting their application. Mg-Ca alloys have huge potential owing to a similar density to bone, good corrosion resistance, and as Mg is essential for Ca incorporation into bone. The objective of the present work is to determine the in vitro degradation and in vivo performance of binary Mg- xCa alloy ( x = 0...
March 1, 2018: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/29587427/surface-modification-of-ti-35nb-10ta-1-5fe-by-the-double-acid-etching-process
#20
Joan Lario, Angélica Amigó, Francisco Segovia, Vicente Amigó
Surface topography and composition influence the osteoblastic proliferation and osseointegration rates, which favor the biomechanical stability of bone anchoring and implants. In recent years, beta titanium alloys have been developed, and are composed of biocompatible elements, have low elastic modulus, high corrosion resistance, and mechanical properties to improve the long performance behavior of biomaterials. In the present research, the influence of the acid-etching process was studied in Ti6Al4V ELI and Ti35Nb10Ta1...
March 26, 2018: Materials
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