keyword
https://read.qxmd.com/read/38547465/tackling-access-and-payer-barriers-for-growth-hormone-therapy-in-saudi-arabia-a-consensus-statement-for-the-saudi-working-group-for-pediatric-endocrinology
#1
REVIEW
Najya Attia, Khairya Moussa, Abdulaziz Altwaim, Abdulmoein Eid Al-Agha, Ashraf A Amir, Aseel Almuhareb
Prompt diagnosis and early treatment are key goals to optimize the outcomes of children with growth hormone deficiency (GHD) and attain the genetically expected adult height. Nonetheless, several barriers can hinder prompt diagnosis and treatment of GHD, including payer-related issues. In Saudi Arabia, moderate-to-severe short stature was reported in 13.1 and 11.7 % of healthy boys and girls, respectively. Several access and payer barriers can face pediatric endocrinologists during the diagnosis and treatment of GHD in Saudi Arabia...
March 29, 2024: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://read.qxmd.com/read/38547135/the-vertigo-trial-protocol-a-prospective-single-center-patient-blinded-study-to-evaluate-efficacy-and-safety-of-prolonged-daily-stimulation-with-a-multichannel-vestibulocochlear-implant-prototype-in-bilateral-vestibulopathy-patients
#2
JOURNAL ARTICLE
Bernd L Vermorken, Benjamin Volpe, Stan C J van Boxel, Joost J A Stultiens, Marc van Hoof, Rik Marcellis, Elke Loos, Alexander van Soest, Chris McCrum, Kenneth Meijer, Nils Guinand, Angélica Pérez Fornos, Vincent van Rompaey, Elke Devocht, Raymond van de Berg
BACKGROUND: A combined vestibular (VI) and cochlear implant (CI) device, also known as the vestibulocochlear implant (VCI), was previously developed to restore both vestibular and auditory function. A new refined prototype is currently being investigated. This prototype allows for concurrent multichannel vestibular and cochlear stimulation. Although recent studies showed that VCI stimulation enables compensatory eye, body and neck movements, the constraints in these acute study designs prevent them from creating more general statements over time...
2024: PloS One
https://read.qxmd.com/read/38547110/what-influences-stroke-survivors-with-physical-disabilities-to-be-physically-active-a-qualitative-study-informed-by-the-theoretical-domains-framework
#3
JOURNAL ARTICLE
L K Kwah, K Doshi, D A De Silva, W M Ng, S Thilarajah
BACKGROUND: Although the benefits of regular physical activity (PA) after stroke are well established, many stroke survivors do not achieve recommended PA levels. To date, studies exploring determinants to PA have not used a behaviour change theory and focused on stroke survivors with physical disabilities. As a precursor to an intervention development study, we aimed to use the Theoretical Domains Framework (TDF) to identify factors influencing PA in stroke survivors with physical disabilities in Singapore...
2024: PloS One
https://read.qxmd.com/read/38546536/-i-would-have-my-children-participate-if-%C3%A2-perceptions-of-canadian-caregivers-towards-school-food-programs
#4
JOURNAL ARTICLE
Suvadra Datta Gupta, Nazeem Muhajarine, Rachel Engler-Stringer
Purpose: The Canadian federal government has expressed an intention to work with provinces and territories to develop a national school food program (SFP). This study aimed to explore caregivers' perception of attributes important to include in a future SFP. Methods: An online cross-sectional survey was conducted. Fifteen elementary schools from high, medium, or low median income neighbourhoods in Saskatoon were invited to participate. School principals sent a survey link to students' caregivers. The 37-item survey included an item with 15 statements asking caregivers to rate the importance of various components of a SFP...
March 28, 2024: Canadian Journal of Dietetic Practice and Research
https://read.qxmd.com/read/38546514/preserving-natural-teeth-to-maintain-oral-health
#5
JOURNAL ARTICLE
(no author information available yet)
Oral health is an important component of general health, and oral disease is one of the most common human diseases that not only affects oral health and quality of life, but is also closely associated with overall health. Natural teeth are important functional organs and are crucial to oral functions and maintaining a healthy life. The Chinese Stomatological Association (CSA) has released this position statement on "Preserving Natural Teeth to Maintain Oral Health", which is one of the most important achievements of the 2021 to 2023 CSA Annual Congress themed "Healthy Mouth, Protecting Natural Teeth", advocating that everyone should take effective measures to protect their natural teeth, maintain oral health and promote general health...
March 28, 2024: Chinese Journal of Dental Research
https://read.qxmd.com/read/38546452/exploring-the-diversity-of-vaginal-microbiota-between-healthy-women-and-cervical-cancer-patients-in-india
#6
JOURNAL ARTICLE
Ashwini Kamble, Shilpa Naik, Manju Talathi, Deepali Jadhav, Meena Sakharkar, Jian Yang, Om Prakash, Ruchika Kaul-Ghanekar
Introduction. Cervicovaginal diversity has been reported as a predictive biomarker for cervical cancer risk. We recently reported the bio-therapeutic potential of vaginal probiotics from healthy Indian women against vaginal pathogens, isolated from the invasive cervical cancer (ICC) patients. Gap Statement. The cervicovaginal microflora from cervical cancer patients has not yet been reported from Indian population. Aim. The present study aimed at comparing the cervicovaginal microbiome between healthy controls (HC) and ICC patients from the Indian population...
March 2024: Journal of Medical Microbiology
https://read.qxmd.com/read/38546297/co-prevalence-of-arterial-aneurysm-location-a-correlation-analysis-based-on-a-retrospective-cross-sectional-observational-study
#7
JOURNAL ARTICLE
Daniel Körfer, Samuel Kilian, Caspar Grond-Ginsbach, Johannes Hatzl, Maani Hakimi, Dittmar Böckler, Philipp Erhart
<b/> Background: The aim of this retrospective single-centre cross-sectional observational study was to investigate co-prevalence of arterial aneurysm location systematically. Patients and methods: Patients with the diagnosis of any arterial aneurysm from January 2006 to January 2016 were investigated in a single centre. Patients with hereditary disorders of connective tissue, systemic inflammatory disease, or arterial pathologies other than true aneurysms were excluded. Aneurysm locations were assessed for every patient included...
March 28, 2024: VASA. Zeitschrift Für Gefässkrankheiten
https://read.qxmd.com/read/38546192/comparison-of-doppler-ultrasonic-sphygmomanometry-oscillometry-and-high-definition-oscillometry-for-non-invasive-blood-pressure-measurement-in-conscious-cats
#8
JOURNAL ARTICLE
Marieke Knies, Erik Teske, Hans Kooistra
OBJECTIVES: Systemic arterial hypertension is a common occurrence and can have serious adverse consequences in cats. Therefore, measuring blood pressure is very important. There are many indirect blood pressure measurement devices available. This study compared Doppler, oscillometric (petMAP Graphic II, SunTech Vet20, the Cardell Insight-X0000) and high-definition oscillometry devices for the non-invasive measurement of blood pressure in conscious cats. METHODS: In this prospective study, blood pressure was measured in 32 cats using the different devices according to the recommendations of the American College of Veterinary Internal Medicine Consensus Statement...
March 2024: Journal of Feline Medicine and Surgery
https://read.qxmd.com/read/38546170/predicting-post-stroke-cognitive-impairment-using-electronic-health-record-data
#9
JOURNAL ARTICLE
Jeffrey M Ashburner, Yuchiao Chang, Bianca Porneala, Sanjula D Singh, Nirupama Yechoor, Jonathan M Rosand, Daniel E Singer, Christopher D Anderson, Steven J Atlas
BACKGROUND: Secondary prevention interventions to reduce post-stroke cognitive impairment (PSCI) can be aided by the early identification of high-risk individuals who would benefit from risk factor modification. AIMS: To develop and evaluate a predictive model to identify patients at increased risk of PSCI over 5 years using data easily accessible from electronic health records. METHODS: Cohort study that included primary care patients from two academic medical centers...
March 28, 2024: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/38545775/advancing-wearable-biosensors-for-congenital-heart-disease-patient-and-clinician-perspectives-a-science-advisory-from-the-american-heart-association
#10
REVIEW
Animesh Tandon, Jennifer N Avari Silva, Ami B Bhatt, Colin K Drummond, Allison C Hill, Amanda E Paluch, Sheradon Waits, Jenny E Zablah, Kevin C Harris
Wearable biosensors (wearables) enable continual, noninvasive physiologic and behavioral monitoring at home for those with pediatric or congenital heart disease. Wearables allow patients to access their personal data and monitor their health. Despite substantial technologic advances in recent years, issues with hardware design, data analysis, and integration into the clinical workflow prevent wearables from reaching their potential in high-risk congenital heart disease populations. This science advisory reviews the use of wearables in patients with congenital heart disease, how to improve these technologies for clinicians and patients, and ethical and regulatory considerations...
March 28, 2024: Circulation
https://read.qxmd.com/read/38545771/liquid-overlay-and-collagen-based-3d-models-for-in-vitro-investigation-of-multiple-myeloma
#11
JOURNAL ARTICLE
Jovana Ilic, Christoph Koelbl, Friederike Teresa Simon, Maximiliane Wußmann, Regina Ebert, Drenka Trivanovic, Marietta Herrmann
Multiple myeloma (MM) clones reside in the bone marrow (BM), which plays a role in its survival and development. The interactions between MM and their neighboring mesenchymal stromal cells (MSCs) have been shown to promote MM growth and drug resistance. However, those interactions are often missing or misrepresented in traditional two-dimensional (2D) culture models. Application of novel three-dimensional (3D) models might recapitulate the BM niche more precisely, which will offer new insights into MM progression and survival...
March 28, 2024: Tissue Engineering. Part C, Methods
https://read.qxmd.com/read/38545679/does-chatgpt-answer-otolaryngology-questions-accurately
#12
JOURNAL ARTICLE
Matthew Maksimoski, Anisha Rhea Noble, David F Smith
OBJECTIVE: Investigate the accuracy of ChatGPT in the manner of medical questions related to otolaryngology. METHODS: A ChatGPT session was opened within which 93 questions were asked related to otolaryngology topics. Questions were drawn from all major domains within otolaryngology and based upon key action statements (KAS) from clinical practice guidelines (CPGs). Twenty-one "patient-level" questions were also asked of the program. Answers were graded as either "correct," "partially correct," "incorrect," or "non-answer...
March 28, 2024: Laryngoscope
https://read.qxmd.com/read/38545671/management-of-adult-primary-immune-thrombocytopenia-delphi-based-consensus-recommendations
#13
JOURNAL ARTICLE
Ahmet Muzaffer Demir, Elif Gülsüm Ümit, Muhlis Cem Ar, Mesut Ayer, Meltem Aylı, Volkan Karakuş, Emin Kaya, Fahir Özkalemkaş, Nilgün Sayınalp, Mehmet Sönmez, Fahri Şahin, Selami Koçak Toprak, Tayfur Toptaş, İrfan Yavaşoğlu, Ümran Çalış
INTRODUCTION: Primary immune thrombocytopenia (pITP) is an acquired autoimmune disorder related with increased destruction or/and impaired production of platelets. Diagnosis and management of ITP is challenging and require expertise and interpretation of international consensus reports and guidelines with national variations of availability. We aimed to assess the agreement of hematologists in Türkiye on certain aspects of both first line and second line management of patients with pITP...
March 28, 2024: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://read.qxmd.com/read/38545434/an-evidence-based-medical-review-on-promoting-gastrointestinal-function-recovery-after-colorectal-cancer-surgery
#14
REVIEW
Chun-Yu Zhao, Wan-Hong Shi, Zheng-Qi Wen, Yong-Mei Jin, Yun-Bo Shang, Lei Zheng, Juan Li, Xin-Min Chen
OBJECTIVE: The objective of this study was to search for, evaluate, and summarize data related to a faster postoperative recovery in patients with colorectal cancer (CRC) based on literature from China as well as internationally. This will serve as an evidence-based foundation for the clinical implementation of enhanced postoperative recovery of gastrointestinal function in patients with CRC. METHODS: Based on the hierarchical "6S" evidence model, we conducted a systematic search of computerized decision-support systems, guideline websites, as well as domestic and international databases for evidence, guidelines, expert consensus statements, clinical decision-making, best practices, evidence summaries, and systematic reviews of interventions focusing on accelerating gastrointestinal function rehabilitation after CRC surgery...
2024: Journal of Multidisciplinary Healthcare
https://read.qxmd.com/read/38544812/left-atrial-appendage-occlusion-british-cardiovascular-intervention-society-and-british-heart-rhythm-society-position-statement
#15
REVIEW
Tim R Betts, Patrick A Calvert, Lee N Graham, Gerald J Clesham, Ashan Gunarathne, Brian Clapp, Dhiraj Gupta, Jan Kovac, James D Newton, David Hildick-Smith
Percutaneous left atrial appendage occlusion aims to reduce the risk of stroke in patients with AF, particularly those who are not good candidates for systemic anticoagulation. The procedure has been studied in large international randomised trials and registries and was approved by the National Institute for Health and Care Excellence in 2014 and by NHS England in 2018. This position statement summarises the evidence for left atrial appendage occlusion and presents the current indications. The options and consensus on best practice for pre-procedure planning, undertaking a safe and effective implant and appropriate post-procedure management and follow-up are described...
2024: Arrhythmia & Electrophysiology Review
https://read.qxmd.com/read/38544326/patients-experience-to-mri-examinations-a-systematic-qualitative-review-with-meta-synthesis
#16
JOURNAL ARTICLE
Isabel Nieto Alvarez, Janika Madl, Linda Becker, Oliver Amft
BACKGROUND: Patients often mention distress, anxiety, or claustrophobia related to MRI, resulting in no-shows, disturbances of the workflow, and lasting psychological effects. Patients' experience varies and is moderated by socio-demographic aspects alongside the clinical condition. While qualitative studies help understand individuals' experiences, to date a systematic review and aggregation of MRI individuals' experience is lacking. PURPOSE: To investigate how adult patients experience MRI, and the characterizing factors...
March 27, 2024: Journal of Magnetic Resonance Imaging: JMRI
https://read.qxmd.com/read/38541976/a-rand-ucla-modified-vas-study-on-telemedicine-telehealth-and-virtual-care-in-daily-clinical-practice-of-vascular-medicine
#17
JOURNAL ARTICLE
Sergio Pillon, Georgia Gomatou, Evangelos Dimakakos, Agata Stanek, Zsolt Pecsvarady, Matija Kozak, Jean-Claude Wautrecht, Katalin Farkas, Gerit-Holger Schernthaner, Mariella Catalano, Aleš Blinc, Grigorios Gerotziafas, Pavel Poredoš, Sergio De Marchi, Michael E Gschwandtner, Endre Kolossváry, Muriel Sprynger, Bahar Fazeli, Aaron Liew, Peter Marschang, Andrzej Szuba, Dusan Suput, Michael Edmonds, Chris Manu, Christian Alexander Schaefer, George Marakomichelakis, Majda Vrkić Kirhmajer, Jonas Spaak, Elias Kotteas, Gianfranco Lessiani, Mary Paola Colgan, Marc Righini, Michael Lichtenberg, Oliver Schlager, Caitriona Canning, Antonella Marcoccia, Anastasios Kollias, Alberta Spreafico
Background: Telemedicine is increasingly used in several fields of healthcare, including vascular medicine. This study aimed to investigate the views of experts and propose clinical practice recommendations on the possible applications of telemedicine in vascular medicine. Methods: A clinical guidance group proposed a set of 67 clinical practice recommendations based on the synthesis of current evidence and expert opinion. The Telemedicine Vascular Medicine Working Group included 32 experts from Europe evaluating the appropriateness of each clinical practice recommendation based on published RAND/UCLA methodology in two rounds...
March 18, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541843/the-reasons-for-the-low-uptake-of-new-antidiabetic-drugs-with-cardiovascular-effects-a-family-doctor-perspective
#18
REVIEW
Tomislav Kurevija, Dunja Šojat, Zvonimir Bosnić, Blerim Mujaj, Silvija Canecki Varžić, Ljiljana Majnarić Trtica
Chronic diseases, such as type 2 diabetes (T2D), are difficult to manage because they demand continuous therapeutic review and monitoring. Beyond achieving the target HbA1c, new guidelines for the therapy of T2D have been introduced with the new groups of antidiabetics, glucagon-like peptide-1 receptor agonists (GLP-1ra) and sodium-glucose cotransporter-2 inhibitors (SGLT2-in). Despite new guidelines, clinical inertia, which can be caused by physicians, patients or the healthcare system, results in T2D not being effectively managed...
March 12, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541212/microrna-expression-in-endometrial-cancer-current-knowledge-and-therapeutic-implications
#19
REVIEW
Irene Iavarone, Rossella Molitierno, Pietro Fumiento, Maria Giovanna Vastarella, Stefania Napolitano, Maria Teresa Vietri, Pasquale De Franciscis, Carlo Ronsini
Background and Objectives : An extracellular vesicle is part of a class of submicron particles derived from cells, mediating cellular crosstalk through microRNA (miRNA). MiRNA is a group of RNA molecules, each of which consists of 15-22 nucleotides and post-transcriptionally modulates gene expression. The complementary mRNAs-onto which the miRNAs hybridize-are involved in processes such as implantation, tumor suppression, proliferation, angiogenesis, and metastasis that define the entire tumor microenvironment...
March 15, 2024: Medicina
https://read.qxmd.com/read/38540893/hedonic-analysis-of-dried-pasta-prices-using-e-commerce-data-an-explorative-study
#20
JOURNAL ARTICLE
Francesco Bimbo, Emilio De Meo, Domenico Carlucci
Italy is the world leader in the production of pasta and the Italian market is characterized by strong price competition among large industrial producers. Thus, recently, many small and medium firms have started to differentiate their products as a way to achieve higher margins and escape from price competition. Using data on the prices and characteristics of dried pasta sold online in the Italian market and a hedonic price model, we estimated the implicit prices associated with several attributes that are currently available for dried pasta...
March 16, 2024: Foods (Basel, Switzerland)
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