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https://www.readbyqxmd.com/read/29352583/description-and-analysis-of-hospital-pharmacies-in-madagascar
#1
H R Ratsimbazafimahefa, F Sadeghipour, P Trouiller, A Pannatier, B Allenet
OBJECTIVE: Madagascar's health care system has operated without formal hospital pharmacies for more than two decades. The gradual integration of pharmacists in public hospitals since 2012 will allow the structuring of this field. This study was conducted to characterize the current situation regarding all aspects relating to the general functioning of hospital pharmacies and the services provided. METHODS: This qualitative research used semi-structured interviews...
January 15, 2018: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/29352545/wpa-who-africa-mental-health-forum-recommendations-and-position-statement
#2
Bernard Janse van Rensburg, Dinesh Bhugra, Shekhar Saxena
No abstract text is available yet for this article.
February 2018: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/29352368/endocrine-therapy-and-related-issues-in-hormone-receptor-positive-early-breast-cancer-a-roundtable-discussion-by-the-breast-cancer-therapy-expert-group-bcteg
#3
REVIEW
Jame Abraham, Humberto Caldera, Robert Coleman, Anthony Elias, Matthew P Goetz, Muaiad Kittaneh, Elyse Lower, Reshma Mahtani, E Terry Mamounas, Mark Pegram, Hope Rugo, Lee Schwartzberg, Tiffany Traina, Chuck Vogel
PURPOSE: Management of breast cancer is a rapidly evolving field, and, although evidence-based guidelines are available for clinicians to provide direction on critical issues in patient care, clinicians often left to address these issues in the context of community practice situations with their patients. These include the patient's comorbid conditions, actual versus perceived benefit of treatments, patient's compliance as well as financial/reimbursement issues, and long-term tolerability of therapy...
January 19, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29351495/implementing-prehospital-evidence-based-guidelines-a-systematic-literature-review
#4
Jennifer N Fishe, Remle P Crowe, Rebecca E Cash, Nikiah G Nudell, Christian Martin-Gill, Christopher T Richards
OBJECTIVE: As prehospital research advances, more evidence-based guidelines (EBGs) are implemented into emergency medical services (EMS) practice. However, incomplete or suboptimal prehospital EBG implementation may hinder improvement in patient outcomes. To inform future efforts, this study's objective was to review existing evidence pertaining to prehospital EBG implementation methods. METHODS: This study was a systematic literature review and evaluation following the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology...
January 19, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29351451/guidelines-for-experimental-models-of-myocardial-ischemia-and-infarction
#5
Merry L Lindsey, Roberto Bolli, John M Canty, Xiao-Jun Du, Nikolaos G Frangogiannis, Stefan Frantz, Robert G Gourdie, Jeffrey W Holmes, Steven P Jones, Robert Kloner, David J Lefer, Ronglih Liao, Elizabeth Murphy, Peipei Ping, Karin Przyklenk, Fabio A Recchia, Lisa Schwartz Longacre, Crystal May Ripplinger, Jennifer E Van Eyk, Gerd Heusch
Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial ischemia with or without reperfusion, and basic and translational research is needed to better understand its underlying mechanisms and consequences for cardiac structure and function. Ischemia underlies a broad range of clinical scenarios ranging from angina to hibernation to permanent occlusion, and while reperfusion is mandatory for salvage from ischemic injury, reperfusion also inflicts injury on its own. In this consensus statement, we present recommendations for animal models of myocardial ischemia and infarction...
January 12, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29350758/obesity-and-pediatric-drug-development
#6
Janelle D Vaughns, Laurie S Conklin, Ying Long, Panli Zheng, Fahim Faruque, Dionna J Green, John N van den Anker, Gilbert J Burckart
There is a lack of dosing guidelines for use in obese children. Moreover, the impact of obesity on drug safety and clinical outcomes is poorly defined. The paucity of information needed for the safe and effective use of drugs in obese patients remains a problem, even after drug approval. To assess the current incorporation of obesity as a covariate in pediatric drug development, the pediatric medical and clinical pharmacology reviews under the Food and Drug Administration (FDA) Amendments Act of 2007 and the FDA Safety and Innovation Act (FDASIA) of 2012 were reviewed for obesity studies...
January 19, 2018: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29350586/mass-media-representations-of-the-evidence-as-a-possible-deterrent-to-recommending-exercise-for-the-treatment-of-depression-lessons-five-years-after-the-extraordinary-case-of-tread-uk
#7
Panteleimon Ekkekakis, Mark E Hartman, Matthew A Ladwig
Exercise or physical activity are recommended options within stepped-care treatment models for depression. However, few physicians present these options to patients, in part because of the impression that the supporting evidence is weak or inconsistent. We speculate that the coocurrence of "counter-messaging" and deficient critical appraisal may lead to such impressions. We focus on TREAD-UK (ISRCTN16900744), the largest trial to investigate "whether physical activity can be an effective treatment for depression within primary care"...
January 19, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29350067/soluble-neuregulin1-is-strongly-up-regulated-in-the-rat-model-of-charcot-marie-tooth-1a-disease
#8
Benedetta Elena Fornasari, Giulia Ronchi, Davide Pascal, Davide Visigalli, Giovanna Capodivento, Lucilla Nobbio, Isabelle Perroteau, Angelo Schenone, Stefano Geuna, Giovanna Gambarotta
Neuregulin1 (NRG1) is a growth factor playing a pivotal role in peripheral nerve development through the activation of the transmembrane co-receptors ErbB2-ErbB3. Soluble NRG1 isoforms, mainly secreted by Schwann cells, are strongly and transiently up-regulated after acute peripheral nerve injury, thus suggesting that they play a crucial role also in the response to nerve damage. Here we show that in the rat experimental model of the peripheral demyelinating neuropathy Charcot-Marie-Tooth 1A (CMT1A) the expression of the different NRG1 isoforms (soluble, type α and β, type a and b) is strongly up-regulated, as well as the expression of NRG1 co-receptors ErbB2-ErbB3, thus showing that CMT1A nerves have a gene expression pattern highly reminiscent of injured nerves...
January 1, 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29350066/differential-expression-of-cytokeratin-14-and-18-in-bladder-cancer-tumorigenesis
#9
Yun-Peng Li, Xiao-Peng Jia, Yu-Qing Jiang, Wei Wang, Yun-Liang Wang, Xiu-Li Wang, Yue-Xian Guo
It has been previously suggested that cytokeratins (CKs) are important diagnostic and prognostic biomarkers for urothelial lesions. Hence it is imperative to understand the expression pattern of cytokeratins during formation of papillary bladder cancer, which was the objective of the current study. Expression pattern of CK14 and CK18 were examined using immunohistochemical staining in a mice model of papillary bladder cancer. Twenty female mice were divided into two groups-group 1 (NT) and group 2, which received N-butyl- N-(4-hydroxybutyl) nitrosamine (BBN) for 20 weeks plus one week without treatment...
January 1, 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29349924/parental-supervision-for-their-children-s-toothbrushing-mediating-effects-of-planning-self-efficacy-and-action-control
#10
Kyra Hamilton, Stephen Cornish, Aaron Kirkpatrick, Jeroen Kroon, Ralf Schwarzer
OBJECTIVES: With 60-90% of children worldwide reportedly experiencing dental caries, poor oral health in the younger years is a major public health issue. As parents are important to children's oral hygiene practices, we examined the key self-regulatory behaviours of parents for supervising their children's toothbrushing using the health action process approach. DESIGN AND METHOD: Participants (N = 281, 197 mothers) comprised Australian parents of 2- to 5-year-olds...
January 18, 2018: British Journal of Health Psychology
https://www.readbyqxmd.com/read/29349263/worldviews-and-trust-of-sources-for-health-information-on-electronic-nicotine-delivery-systems-effects-on-risk-perceptions-and-use
#11
Scott R Weaver, Amelia Jazwa, Lucy Popova, Paul Slovic, Richard B Rothenberg, Michael P Eriksen
Public health agencies, the news media, and the tobacco/vapor industry have issued contradictory statements about the health effects of electronic nicotine delivery systems (ENDS). We investigated the levels of trust that consumers place in different information sources and how trust is associated with cultural worldviews, risk perceptions, ENDS use, and sociodemographic characteristics using a nationally representative sample of 6051 U.S. adults in 2015. Seventeen percent of adults were uncertain about their trust for one or more potential sources...
December 2017: SSM—Population Health
https://www.readbyqxmd.com/read/29347973/believability-of-messages-about-preventing-breast-cancer-and-heart-disease-through-physical-activity
#12
Tanya R Berry, Kelvin E Jones, Kerry S Courneya, Kerry R McGannon, Colleen M Norris, Wendy M Rodgers, John C Spence
BACKGROUND: The purpose of this research was to examine the relationships of self-reported physical activity to involvement with messages that discuss the prevention of heart disease and breast cancer through physical activity, the explicit believability of the messages, and agreement (or disagreement) with specific statements about the messages or disease beliefs in general. METHODS: A within subjects' design was used. Participants (N = 96) read either a breast cancer or heart disease message first, then completed a corresponding task that measured agreement or disagreement and confidence in the agreement or disagreement that 1) physical activity 'reduces risk/does not reduce risk' of breast cancer or heart disease, 2) that breast cancer or heart disease is a 'real/not real risk for me', 3) that women who get breast cancer or heart disease are 'like/not like me', and 4) that women who get breast cancer or heart disease are 'to blame/not to blame'...
January 18, 2018: BMC Psychology
https://www.readbyqxmd.com/read/29347931/attitudes-towards-tooth-fillings-in-tanzanian-adults-and-its-association-with-previous-filling-experience
#13
Kasusu K Nyamuryekung'e, Satu M Lahti, Risto J Tuominen
BACKGROUND: Tooth filling treatment is utilized at low levels in many low and middle-income countries (LMICs), further, little is known about the prevailing attitudes towards such treatment. This study aimed to assess attitudes towards tooth filling among Tanzanian adults and how previous tooth filling experience is associated with these attitudes. METHODS: A pretested structured questionnaire was distributed among 1522 out-patients in four regional hospitals in Tanzania in 2015-16...
January 18, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29346743/publishing-aade-s-position-statements
#14
James A Fain
No abstract text is available yet for this article.
February 2018: Diabetes Educator
https://www.readbyqxmd.com/read/29346638/standardized-languages-and-notations-for-graphical-modelling-of-patient-care-processes-a-systematic-review
#15
Pierpaolo Mincarone, Carlo Giacomo Leo, Maria Del Mar Trujillo-Martín, Jan Manson, Roberto Guarino, Giuseppe Ponzini, Saverio Sabina
Purpose: The importance of working toward quality improvement in healthcare implies an increasing interest in analysing, understanding and optimizing process logic and sequences of activities embedded in healthcare processes. Their graphical representation promotes faster learning, higher retention and better compliance. The study identifies standardized graphical languages and notations applied to patient care processes and investigates their usefulness in the healthcare setting. Data sources: Peer-reviewed literature up to 19 May 2016...
January 16, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29346001/strategies-and-challenges-in-preventing-violence-against-canadian-indoor-sex-workers
#16
Vicky Bungay, Adrian Guta
OBJECTIVES: To examine indoor sex workers' strategies in preventing workplace violence and influential socio-structural conditions. METHODS: Data included qualitative interviews with 85 sex workers in British Columbia, Canada, from 2014 through 2016. For analyses, we used interpretive thematic techniques informed by World Health Organization position statements on violence. RESULTS: Robbery, nonpayment, financial exploitation, and privacy violations were frequent types of violence perpetrated by clients, landlords, and neighbors...
January 18, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29345524/recovery-and-performance-in-sport-consensus-statement
#17
Michael Kellmann, Maurizio Bertollo, Laurent Bosquet, Michel Brink, Aaron Coutts, Rob Duffield, Daniel Erlacher, Shona Halson, Anne Hecksteden, Jahan Heidari, Romain Meeusen, Iñigo Mujika, Claudio Robazza, Sabrina Skorski, Ranel Venter, Jürgen Beckmann
The relationship between recovery and fatigue and its impact on performance has attracted the interest of sports science for many years. An adequate balance between stress (training and competition load, other life demands) and recovery is essential for athletes to achieve continuous high-level performance. Research has focused on the examination of physiological and psychological recovery strategies to compensate external and internal training and competition loads. A systematic monitoring of recovery and the subsequent implementation of recovery routines aims at maximizing performance and preventing negative developments such as underrecovery, non-functional overreaching, the overtraining syndrome, injuries, or illnesses...
January 18, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29345299/the-continuing-misuse-of-null-hypothesis-significance-testing-in-biological-anthropology
#18
EDITORIAL
Richard J Smith
There is over 60 years of discussion in the statistical literature concerning the misuse and limitations of null hypothesis significance tests (NHST). Based on the prevalence of NHST in biological anthropology research, it appears that the discipline generally is unaware of these concerns. The p values used in NHST usually are interpreted incorrectly. A p value indicates the probability of the data given the null hypothesis. It should not be interpreted as the probability that the null hypothesis is true or as evidence for or against any specific alternative to the null hypothesis...
January 18, 2018: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/29345215/relationship-of-weekend-warrior-and-regular-physical-activity-patterns-with-metabolic-syndrome-and-its-associated-diseases-among-chinese-rural-adults
#19
Jing Xiao, Minjie Chu, Huan Shen, Wenlong Ren, Zhou Li, Tianqi Hua, Hong Xu, Yuanyuan Liang, Yuexia Gao, Xun Zhuang
Little is known about the "weekend warrior" pattern of physical activity (PA) where people perform all their PA in 1 or 2 sessions per week. We investigated the relationship of weekend warrior and other PA patterns with metabolic syndrome (MS) and its associated diseases. Data on sociodemographic and lifestyle characteristics were collected from the Nantong Metabolic Syndrome Study that included 13,505 women and 6,997 men between 2007 and 2008. Compared with inactive participants, weekend warriors were at lower risk of MS, diabetes, and hypertension; respective odds ratios (95% confidence intervals) for men and women were 0...
January 18, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29344727/work-related-stress-as-a-cardiovascular-risk-factor-in-police-officers-a-systematic-review-of-evidence
#20
N Magnavita, I Capitanelli, S Garbarino, E Pira
PURPOSE: Several studies suggest that work-related stress in police officers may be associated with an increased risk of cardiovascular diseases. A systematic review of studies is, however, still lacking. METHOD: According to PRISMA statement, a systematic search of PubMed, ISI Web of Science, Cinahl and PsychInfo electronic databases was undertaken. Studies published in English between 1/1/2000 and 31/12/2016 were included. A studies quality assessment was performed using the Newcastle Ottawa scale (NOS)...
January 17, 2018: International Archives of Occupational and Environmental Health
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