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https://www.readbyqxmd.com/read/29791429/-clinical-practice-guideline-for-the-evaluation-and-management-of-upper-gastrointestinal-bleeding-for-the-peruvian-social-security-essalud
#1
Jorge Vásquez-Quiroga, Alvaro Taype-Rondan, Jessica Hanae Zafra-Tanaka, Ericson Arcana-López, Luis Cervera-Caballero, Javier Contreras-Turin, Katherine Guzmán-Cáceres, Juan Llatas-Perez, Luis Marin-Calderón, Alejandro Piscoya, Daniel Vargas-Blácido, Nelly Vásquez-Valverde, Raúl Timaná-Ruiz
OBJECTIVE: To provide evidence-based clinical recommendations for the evaluation and management of patients with upper gastrointestinal bleeding (UGB) in the Peruvian Social Security (EsSalud). MATERIALS AND METHODS: A local guideline development group (local GDG) was established, including specialists in gastroenterology and methodologists. The local GDG formulated 11 clinical questions to be answered by this clinical practice guide (CPG). We searched and selected CPG of UGB published from 2012, which answered the posed questions and obtained a score higher than 60% in domains 1 and 3 of the Appraisal of Guidelines for Research and Evaluation II (AGREE-II) tool...
January 2018: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/29790089/red-drum-sciaenops-ocellatus-growth-and-expression-of-bile-salt-dependent-lipase-in-response-to-increasing-dietary-lipid-supplementation
#2
Mayra L González-Félix, Delbert M Gatlin, Martin Perez-Velazquez, Ken Webb, Armando García-Ortega, Michael Hume
Sciaenops ocellatus has a long history in aquaculture and many difficulties associated with its commercial culture have been addressed and successfully resolved; nevertheless, further research in lipid nutrition could address more comprehensive questions on the way these nutrients are utilized. The purpose of this study was to evaluate S. ocellatus growth and lipase gene expression in response to increasing dietary lipid supplementation. Four experimental diets were formulated to provide 3, 10, 16, or 23% lipid using menhaden fish oil...
May 22, 2018: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29787391/comparing-wavefront-optimized-wavefront-guided-and-topography-guided-laser-vision-correction-clinical-outcomes-using-an-objective-decision-tree
#3
Karl Stonecipher, Joseph Parrish, Megan Stonecipher
PURPOSE OF REVIEW: This review is intended to update and educate the reader on the currently available options for laser vision correction, more specifically, laser-assisted in-situ keratomileusis (LASIK). In addition, some related clinical outcomes data from over 1000 cases performed over a 1-year are presented to highlight some differences between the various treatment profiles currently available including the rapidity of visual recovery. The cases in question were performed on the basis of a decision tree to segregate patients on the basis of anatomical, topographic and aberrometry findings; the decision tree was formulated based on the data available in some of the reviewed articles...
May 18, 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29783200/blood-lead-and-cadmium-levels-in-preschool-children-and-associated-risk-factors-in-s%C3%A3-o-paulo-brazil
#4
Kelly Polido Kaneshiro Olympio, Júlia Prestes da Rocha Silva, Agnes Soares da Silva, Vanessa Cristina de Oliveira Souza, Marília Afonso Rabelo Buzalaf, Fernando Barbosa, Maria Regina Alves Cardoso
In Brazil, there are scarce data on lead (Pb) and cadmium (Cd) contamination, especially for more vulnerable populations such as preschool children. In this paper, we answer two questions: (1) What are the exposure levels of lead and cadmium in preschool children, in Sao Paulo, Brazil? and (2) What are the risk factors associated with this exposure? This cross-sectional study included 50 day care centers (DCCs), totaling 2463 children aged 1-4 years. Venous blood samples were analyzed by ICP-MS. Questionnaires were administered to the parents...
May 18, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29778724/a-tangle-of-forms-and-phylogeny-extensive-morphological-homoplasy-and-molecular-clock-heterogeneity-in-bonnetina-and-related-tarantulas
#5
David Ortiz, Oscar F Francke, Jason E Bond
Tarantula spider systematics has long been considered problematic. Species diagnosis and phylogenetic hypotheses have historically relied on morphological features, which are known to be relatively conserved and/or highly homoplastic across the family. Morphology-based attempts to clarify the phylogeny of the highly diverse New World Theraphosinae, have only been moderately successful, and the time-frame of tarantulas' evolution is nearly terra incognita. Here we present a molecular phylogenetic analysis of the Theraphosinae genus Bonnetina and related lineages, employing one mitochondrial (COI) and five nuclear (ITS1, EF1G, MID1IP1, MRPL44, and I3568) loci...
May 17, 2018: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/29774504/environmental-toxins-and-male-fertility
#6
REVIEW
Mahmoud Mima, David Greenwald, Samuel Ohlander
PURPOSE OF REVIEW: Global industrialization has increased population exposure to environmental toxins. A global decline in sperm quality over the last few decades raises questions about the adverse impact of environmental toxins on male reproductive health. RECENT FINDINGS: Multiple animal- and human-based studies on exposure to environmental toxins suggest a negative impact on semen quality, in terms of sperm concentration, motility, and/or morphology. These toxins may exert estrogenic and/or anti-androgenic effects, which in turn alter the hypothalamic-pituitary-gonadal axis (HPGA), induce sperm DNA damage, or cause sperm epigenetic changes...
May 17, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29774368/-formation-of-quality-of-counselling-in-nursing-development-and-testing-of-a-causal-model-for-care-counselling-according-to-%C3%A2-7a-sgb-xi
#7
Peter Michell-Auli, Regina Gerlich
At present, the question of what quality of counselling means is very open. This is particularly reflected in the lack of a widely accepted catalogue of criteria. For evaluations and further developments of corresponding advisory services, this represents an essential issue. In this article a causal-theoretical model for quality in care counselling is developed and tested based on empirical data collected by compass private pflegeberatung (care consultants). The results lead to implications for the legally formulated evaluation order according to § 7a of the Social Security Code XI (SGB XI)...
May 17, 2018: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/29771554/perceived-crisis-and-reforms-issues-explanations-and-remedies
#8
Paul De Boeck, Minjeong Jeon
An overview and discussion is made of the perceived replication crisis in terms of end problems, explanations, and remedies. Following a discussion of a published large-scale replication study and a review of the meta-analysis literature, we come to the conclusion that many effects are small and that on average the variance of the effects is roughly 10% to 25% of the population variance, most likely because of context dependencies. The proposed explanations such as questionable and suboptimal research practices (low power, poor measurement quality, and the use of NHST) are discussed, as well as more distal explanatory factors such as journals, funding agencies, and institutions...
May 17, 2018: Psychological Bulletin
https://www.readbyqxmd.com/read/29769495/analyses-of-the-neuroanatomy-portion-of-the-anatomy-question-papers-for-written-summative-assessment-at-the-medical-undergraduate-level-in-bangladesh
#9
M Akter, K M Shamim, N F Amin
Neuroanatomy is a vital part of the undergraduate medical (MBBS) Anatomy curriculum of different universities of Bangladesh. The teaching-learning and assessment of Neuroanatomy have gone through significant changes in current times in various parts of the world. Neuroanatomy textbooks are supposed to be useful reflectors of these changes and of the present inclinations. The importance of an understanding approach towards Neuroanatomy is beyond doubt. Consequently, the contemporary Neuroanatomy books are inclined more towards an understanding approach in their presentation...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769384/meta-research-on-oncology-trials-a-toolkit-for-researchers-with-limited-resources
#10
Rachel P Riechelmann, Julien Péron, Bostjan Seruga, Everardo D Saad
"Meta-research" is a discipline that investigates research practices. Meta-research on clinical trials is an attempt to summarize descriptive and methodological features of published or ongoing clinical trials, including aspects of their implementation, design, analysis, reporting, and interpretation. In this type of investigation, the unit of analysis is a primary source of information about a clinical trial (e.g., published reports, study protocols, or abstracts), with meta-research being a second layer of information that summarizes what is known from various primary sources...
May 16, 2018: Oncologist
https://www.readbyqxmd.com/read/29766455/consensus-document-on-the-progression-and-treatment-response-criteria-in-gastroenteropancreatic-neuroendocrine-tumors
#11
X Merino-Casabiel, J Aller, J Arbizu, R García-Figueiras, C González, E Grande, P Jiménez-Fonseca, M I Sevilla, J Capdevila
PURPOSE: Gastroenteropancreatic neuroendocrine tumors are a heterogeneous group of low incidence neoplasms characterized by a low proliferative activity and slow growth. Their response to targeted therapies is heterogeneous and often does not lead to tumor shrinkage. Thus, evaluation of the therapeutic response should differ from other kind of tumors. METHODS: To answer relevant questions about which techniques are best in the assessment of progression or treatment response a RAND/UCLA-based consensus process was implemented...
May 15, 2018: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29761902/the-influence-of-implant-abutment-connection-to-peri-implant-bone-loss-a-systematic-review-and-meta-analysis
#12
REVIEW
Riccardo Caricasulo, Luciano Malchiodi, Paolo Ghensi, Giuliano Fantozzi, Alessandro Cucchi
PURPOSE: Different implant-abutment connections are available and it has been claimed they could have an effect on marginal bone loss. The aim of this review is to establish if implant connection configuration influences peri-implant bone loss (PBL) after functional loading. METHODS: A specific question was formulated according to the Population, Intervention, Control, and Outcome (PICO): Does the type of implant-abutment connection (external, internal, or conical) have an influence on peri-implant bone loss? A PubMed/MEDLINE electronic search was conducted to identify English language publications published in international journals during the last decade (from 2006 to 2016)...
May 15, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29760057/weak-galilean-invariance-as-a-selection-principle-for-coarse-grained-diffusive-models
#13
Andrea Cairoli, Rainer Klages, Adrian Baule
How does the mathematical description of a system change in different reference frames? Galilei first addressed this fundamental question by formulating the famous principle of Galilean invariance. It prescribes that the equations of motion of closed systems remain the same in different inertial frames related by Galilean transformations, thus imposing strong constraints on the dynamical rules. However, real world systems are often described by coarse-grained models integrating complex internal and external interactions indistinguishably as friction and stochastic forces...
May 14, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29754528/canadian-patients-preferences-in-topical-psoriasis-care-insights-from-the-propel-surveys
#14
Ronald Vender, Melinda J Gooderham, Lyn C Guenther, Dimitrios Kyritsis, Jaggi Rao, Alice Kowalczyk, John Ashkenas
BACKGROUND: Patients with psoriasis of all severities employ topical treatment, either alone or in combination. Promoting Patient Engagement at the Leading Edge of Topical Psoriasis Treatment (PROPEL) surveyed Canadian dermatologists and their patients about their attitudes toward topical care. OBJECTIVES: To identify gaps between patients and dermatologists regarding the burden of psoriasis, the burden of treatment, and priorities for topical care to Canadian patients with psoriasis...
May 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29752924/emergency-contraception-supply-in-australian-pharmacies-after-the-introduction-of-ulipristal-acetate-a-mystery-shopping-mixed-methods-study
#15
Jack Charles Collins, Carl Richard Schneider, Rebekah Jane Moles
OBJECTIVE: To explore the supply of emergency contraception (EC) from Australian community pharmacies after the introduction of ulipristal acetate (UPA), and to explore pharmacists' knowledge, decision-making, attitudes, and beliefs surrounding supplying EC. STUDY DESIGN: A mixed-methods approach of mystery shopping with structured interview was employed. From August-November 2017, 20 pharmacy students mystery-shopped 10 community pharmacies in metropolitan Sydney, Australia, requesting "the morning after pill"...
May 9, 2018: Contraception
https://www.readbyqxmd.com/read/29751829/querying-archetype-based-ehrs-by-search-ontology-based-xpath-engineering
#16
Stefan Kropf, Alexandr Uciteli, Katrin Schierle, Peter Krücken, Kerstin Denecke, Heinrich Herre
BACKGROUND: Legacy data and new structured data can be stored in a standardized format as XML-based EHRs on XML databases. Querying documents on these databases is crucial for answering research questions. Instead of using free text searches, that lead to false positive results, the precision can be increased by constraining the search to certain parts of documents. METHODS: A search ontology-based specification of queries on XML documents defines search concepts and relates them to parts in the XML document structure...
May 11, 2018: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/29743830/predicting-outcomes-to-optimize-disease-management-in-inflammatory-bowel-disease-in-japan-their-differences-and-similarities-to-western-countries
#17
REVIEW
Taku Kobayashi, Tadakazu Hisamatsu, Yasuo Suzuki, Haruhiko Ogata, Akira Andoh, Toshimitsu Araki, Ryota Hokari, Hideki Iijima, Hiroki Ikeuchi, Yoh Ishiguro, Shingo Kato, Reiko Kunisaki, Takayuki Matsumoto, Satoshi Motoya, Masakazu Nagahori, Shiro Nakamura, Hiroshi Nakase, Tomoyuki Tsujikawa, Makoto Sasaki, Kaoru Yokoyama, Naoki Yoshimura, Kenji Watanabe, Miiko Katafuchi, Mamoru Watanabe, Toshifumi Hibi
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disease of the gastrointestinal tract, with increasing prevalence worldwide. IBD Ahead is an international educational program that aims to explore questions commonly raised by clinicians about various areas of IBD care and to consolidate available published evidence and expert opinion into a consensus for the optimization of IBD management. Given differences in the epidemiology, clinical and genetic characteristics, management, and prognosis of IBD between patients in Japan and the rest of the world, this statement was formulated as the result of literature reviews and discussions among Japanese experts as part of the IBD Ahead program to consolidate statements of factors for disease prognosis in IBD...
April 2018: Intestinal Research
https://www.readbyqxmd.com/read/29742226/influenza-a-non-h1n1-associated-with-acute-respiratory-failure-and-acute-renal-failure-in-a-previously-vaccinated-cystic-fibrosis-patient
#18
Louise Piva Penteado, Cecília Susin Osório, Antônio Balbinotto, Paulo de Tarso Roth Dalcin
In the 2014 - 2015 season, most influenza infections were due to A (H3N2) viruses. More than two-thirds of circulating A (H3N2) viruses are antigenically and genetically different (drifted) from the A (H3N2) vaccine component of 2014 - 2015 northern and southern Hemisphere seasonal influenza vaccines. The purpose of this paper is to report a case of seasonal influenza A non-H1N1 infection that occurred in June 2015 in an adult cystic fibrosis patient with severe lung disease previously vaccinated with the anti-flu trivalent vaccine...
March 2018: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/29741296/assessment-and-management-of-bone-health-in-women-with-oestrogen-receptor-positive-breast-cancer-receiving-endocrine-therapy-position-statement-of-the-endocrine-society-of-australia-the-australian-and-new-zealand-bone-mineral-society-the-australasian-menopause
#19
Mathis Grossmann, Sabashini Ramchand, Frances Milat, Amanda Vincent, Elgene Lim, Mark A Kotowicz, Jill Hicks, Helena Teede
OBJECTIVE: To formulate clinical consensus recommendations on bone health assessment and management of women with oestrogen receptor-positive early breast cancer receiving endocrine therapy. METHODS: Representatives appointed by relevant Australian Medical Societies used a systematic approach for adaptation of guidelines (ADAPTE) to derive an evidence-informed position statement addressing five key questions. RESULTS: Women receiving adjuvant aromatase inhibitors and the subset of premenopausal woman on tamoxifen have accelerated bone loss and increased fracture risk...
May 9, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29736071/assessing-the-extent-of-utilization-of-biopsychosocial-model-in-doctor-patient-interaction-in-public-sector-hospitals-of-a-developing-country
#20
Maha Nadir, Muhammad Hamza, Nadir Mehmood
Background: Biopsychosocial (BPS) model has been a mainstay in the ideal practice of modern medicine. It is attributed to improve patient care, compliance, and satisfaction and to reduce doctor-patient conflict. The study aimed to understand the importance given to BPS model while conducting routine doctor-patient interactions in public sector hospitals of a developing country where health resources are limited. The study was conducted in Rawalpindi, Pakistan. Materials and Methods: The study design is qualitative...
January 2018: Indian Journal of Psychiatry
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