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Neurocogntive disorders

Cole Korponay, George C Nitzburg, Anil K Malhotra, Pamela DeRosse
Considerable data support the phenomenological and temporal continuity between subclinical psychosis and psychotic disorders. In recent years, neurocognitive deficits have increasingly been recognized as a core feature of psychotic illness but there are few data seeking to elucidate the relationship between subclinical psychosis and neurocogntive deficits in non-clinical samples. The goal of the present study was to examine the relationship between subclinical positive and negative symptoms, as measured by the Community Assessment of Psychic Experiences (CAPE) and performance on the MATRICS Consensus Cognitive Battery (MCCB) in a large (n=303) and demographically diverse non-clinical sample...
December 1, 2014: Schizophrenia Research. Cognition
Desiree A Byrd, Robert P Fellows, Susan Morgello, Donald Franklin, Robert K Heaton, Reena Deutsch, J Hampton Atkinson, David B Clifford, Ann C Collier, Christina M Marra, Benjamin Gelman, J Allen McCutchan, Nichole A Duarte, David M Simpson, Justin McArthur, Igor Grant
BACKGROUND: : To determine how serious a confound substance use (SU) might be in studies on HIV-associated neurocognitive disorder (HAND), we examined the relationship of SU history to neurocognitive impairment (NCI) in participants enrolled in the Central Nervous System HIV Antiretroviral Therapy Effects Research study. METHODS: : After excluding cases with behavioral evidence of acute intoxication and histories of factors that independently could account for NCI (eg, stroke), baseline demographic, medical, SU, and neurocognitive data were analyzed from 399 participants...
October 1, 2011: Journal of Acquired Immune Deficiency Syndromes: JAIDS
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