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https://www.readbyqxmd.com/read/29290068/topical-minoxidil-versus-topical-diltiazem-for-chemical-sphincterotomy-of-chronic-anal-fissure-a-prospective-randomized-double-blind-clinical-trial
#1
Mina Alvandipour, Shahram Ala, Mehdi Khalvati, Jamshid Yazdanicharati, Neda Koulaeinejad
BACKGROUND: Anal fissure is a common anorectal problem causing severe pain and discomfort to the patients. Chemical sphincterotomy has emerged as a noninvasive alternative to the surgical methods of fissure treatment. The objective of this study was evaluation of the efficacy and the adverse effects of topically applied minoxidil in chemical sphincterotomy of chronic anal fissure in comparison with topical diltiazem. METHODS: A total of 88 patients with chronic anal fissure aged between 15 and 65 years were included in this double-blind, randomized clinical trial and were randomly assigned to either 0...
December 31, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29246589/results-of-the-national-survey-on-the-treatment-of-chronic-anal-fissure-in-spanish-hospitals
#2
M Del Mar Aguilar, Pedro Moya, M José Alcaide, Alba Fernández, M Amparo Gómez, Jair Santos, Rafael Calpena, Antonio Arroyo
INTRODUCTION: The treatment of chronic anal fissure (FAC) differs depending on the professional. To come to a consensus, the current situation in Spain should be studied. The aim of this study is to evaluate the current situation of the management of FAC in Spanish hospitals. METHODS: Descriptive study, with data from a survey of surgeons of the Spanish Association of Coloproctology. Data was collected according to the doctor's autonomous community, type of hospital and professional category; FAC management data and 3 clinical cases...
December 12, 2017: Cirugía Española
https://www.readbyqxmd.com/read/29233787/anal-advancement-flap-versus-lateral-internal-sphincterotomy-for-chronic-anal-fissure-a-systematic-review-and-meta-analysis
#3
REVIEW
Shaheel Mohammad Sahebally, Stewart Redmond Walsh, Waqas Mahmood, Thomas Michael Aherne, Myles Richard Joyce
BACKGROUND: Chronic anal fissures (CAF) are common and associated with reduced quality of life. Lateral internal sphincterotomy (LIS) is frequently carried out but carries a significant risk of anal incontinence. Anal advancement flap (AAF) has been advocated as an alternative, 'sphincter-preserving' procedure. We aimed to perform a systematic review and meta-analysis to compare the efficacy of both techniques in the treatment of CAF. METHODS: The online databases of PubMed/Medline, CINAHL, EMBASE and Cochrane Central Register of Controlled Trials were searched from inception to January 2017...
December 9, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29231588/-acupoint-catgut-embedding-therapy-in-treatment-of-anal-fissure-at-%C3%A2-and-%C3%A2-stages-a-randomized-controlled-trial
#4
Songhua Deng, Li Mo, Wenwen Deng, Sai Chen, Yongheng He
OBJECTIVE: To evaluate the difference in the clinical therapeutic effects on anal fissure at Ⅰ and Ⅱ stages between the acupoint catgut embedding therapy and western medication. METHODS: Sixty patients of anal fissure at Ⅰ and Ⅱ stages were randomized into an embedding therapy group and a western medication group, 30 cases in each one. In the embedding therapy group, the acupoint catgut embedding therapy was applied at bilateral Tianshu (ST 25), Changqiang (GV 1), bilateral Chengshan (BL 57) and Tigangxue (Extra), once a week...
April 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29205737/combined-treatment-approach-to-chronic-anal-fissure-with-associated-anal-fistula
#5
Andrew J FitzDowse, Corina C Behrenbruch, Ian P Hayes
BACKGROUND: Anal fistula in association with chronic anal fissure (fissure-fistula) is infrequently described. Recognizing this association and managing both components may help prevent some treatment failures seen with chronic anal fissure. This study aims to report on the outcomes of 20 consecutive patients with fissure-fistula managed with fistulotomy and injection of botulinum A toxin. METHODS: The study is a retrospective, observational study, assessing the success of symptom resolution following fistulotomy with botulinum A toxin, in patients identified as having a chronic anal fissure with associated anal fistula...
December 3, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29166553/botulinum-toxin-injection-versus-topical-nitrates-for-chronic-anal-fissure-an-updated-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#6
REVIEW
Shaheel M Sahebally, Babak Meshkat, Stewart R Walsh, David Beddy
BACKGROUND: Chronic anal fissures (CAF) are frequently encountered in coloproctology clinics. Chemical sphincterotomy with pharmacological agents is recommended as first-line therapy. Topical nitrates (TN) heal CAF effectively but recurrences are common. An alternative treatment modality is injection of botulinum toxin (BT) into the anal sphincter. We aimed to perform an updated systematic review and meta-analysis to compare the effectiveness of BT and TN in the management of CAF. METHODS: PubMed, EMBASE and Cochrane databases were searched for relevant articles from inception until March 2017...
November 22, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29165416/-a-case-of-progressive-glaucoma-against-the-background-of-chronic-constipation
#7
A E Vasil'eva, N V Makashova, I A Ronzina, O Yu Kolosova, K V Goncharenko
The authors describe a case of severe glaucoma in the only seeing eye of a patient with venous circulation disturbance resulting from a chronic anal fissure complicated with progressive anal stenosis, severe sphincter spasm, and pain syndrome. The article presents the results of multiple clinical ophthalmological tests and instrumental examinations performed before and after surgical intervention that evidence the importance of venous circulation disturbances for glaucoma development.
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29105520/preparation-and-characterization-of-textile-based-carrier-systems-for-anal-fissure-treatment
#8
A M Sarıışık, S Y Karavana, G C Türkoğlu, S Rençber, T Önder
Anal fissure is common and painful disease of anorectum. In this study, microparticles containing nifedipine and lidocaine HCl were prepared by spray drying and applied to bio-degradable and bio-stable tampons. Characterization of microparticles was determined by visual analyses, mass yield, particle size measurement, encapsulation efficiency, drug loading and in vitro drug release. Mass yield was between 5.5 and 45.9%. The particle size was between 15.1 and 26.8 µm. Encapsulation efficiency were 96.142 ± 5...
November 5, 2017: Journal of Microencapsulation
https://www.readbyqxmd.com/read/29080958/high-dose-versus-low-dose-botulinum-toxin-in-anal-fissure-disease
#9
P Ravindran, D L Chan, C Ciampa, R George, G Punch, S I White
BACKGROUND: There is no consensus on the optimal dosage of botulinum toxin (BT) as a sphincter sparing alternative to lateral internal sphincterotomy for chronic anal fissure. The aim of this study was to assess the long-term efficacy of high-dose BT as well as the presence of incontinence following the treatment of chronic anal fissure at a single institution. METHODS: A retrospective case-control study was performed at a single institution over a 6-year period (2009-2014)...
October 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29076452/-treatment-of-anal-fissures
#10
Nina Sonne Bundgaard, Kikke Kirsten Hagen, Andreas Nordholm-Carstensen
Anal fissure is a common ailment, however, the pathophysiology and optimal treatment strategy is unclear. Anal fissures may be classified as acute or chronic. Acute fissures are effectively treated and prevented with conservative measures, whereas chronic fissures typically require medical or surgical therapy. Invasive interventions have superior healing rates compared with local medical therapies, but may cause persistent incontinence. New interventions are constantly introduced and may be of value in patients with high risk of incontinence, but more evidence is currently needed...
October 23, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29034654/surgical-treatment-of-chronic-anal-fissure
#11
Fausto Fama', Maria Gioffrè-Florio
No abstract text is available yet for this article.
August 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28948431/vulvar-involvement-in-pediatric-crohn-s-disease-a-systematic-review
#12
REVIEW
Roberta Granese, Gloria Calagna, Giuliana Morabito, Carmine Carriero, Antonio Perino, Gabriele Tonni, Claudio Romano
PURPOSE: The aim of the study is to report a systematic review (from 2000 to 2017) of all pediatric cases of vulvar Crohn's disease (VCD) and to highlight the key-points for a correct diagnosis and management of this rare condition. METHODS: An electronic search using the Pubmed/Medline, Scopus, EMBASE, Cochrane database and Google Scholar database was performed according to PRISMA guidelines. RESULTS: Twenty pediatric studies and 22 cases of VCD were included for analysis...
September 25, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28936381/anal-canal-gas-gangrene-in-aplastic-anaemia-rare-yet-lethal-entity-a-caveat
#13
Sundaramurthi Sudharsanan, Chellappa Vijayakumar, Kumar Manish, T P Elamurugan, Ali S Manwar
Gas gangrene is one of the most serious infections of traumatic and surgical wounds. The importance lies in the fact that, if not managed at the right time, the condition is fatal. Though perianal cellulitis and gangrene are commonly reported in immunocompromised patients, we report the case of a patient with gas gangrene involving only the anal canal extending to the rectum, a rare presentation to be reported in literature.  An 18-year-old lady, a patient of aplastic anaemia - immunodeficiency, developed gas gangrene of the anal canal possibly due to faecal contamination of anal fissures...
July 13, 2017: Curēus
https://www.readbyqxmd.com/read/28924546/sirenomelia-associated-with-hypoplastic-left-heart-in-a-newborn
#14
H Turgut, R Ozdemir, I K Gokce, C Karakurt, A Karadag
Sirenomelia, also known as "mermaid malformation/syndrome," is a rare, serious congenital anomaly characterized by variable degrees of fusion of the lower limbs and associated with severe malformations of vertebral, genitourinary, cardiovascular system and single umbilical artery. The first pregnancy of a 25-year-old woman resulted in one twin born by Cesarian section at 32 weeks' gestation, who was referred to our hospital with cyanosis, a congenital anomaly and respiratory distress. On physical examination, there was no urogenital region and anal fissure and gender was indeterminate...
June 30, 2017: Balkan Journal of Medical Genetics: BJMG
https://www.readbyqxmd.com/read/28918703/a-randomized-multicenter-clinical-trial-of-rph-with-the-simplified-milligan-morgan-hemorrhoidectomy-in-the-treatment-of-mixed-hemorrhoids
#15
Yong-Heng He, Zhi-Jun Tang, Xiang-Tong Xu, De-Quan Huang, Li-Shun Zhang, Qing-Zhu Tang, Zhi-Min Fan, Xian-Jun Zou, Guo-Jun Zou, Chong-Yang Zhang, Fan Hu, Biao Xie, Yan-Hua Li, Yao Tong, Hong-Chang Liu, Ke Li, Yu-Lian Luo, Fei Liu, Guang-Wei Situ, Zuo-Long Liu
PURPOSE: To explore the safety and efficacy of Ruiyun procedure for hemorrhoids (RPH) or RPH with the simplified Milligan-Morgan hemorrhoidectomy (sMMH) in the treatment of mixed hemorrhoids. METHODS: This is a randomized, controlled, balanced, multicenter study of 3000 patients with mixed hemorrhoids. The outcomes and postoperative complications were compared between 5 types of surgeries. RESULTS: The efficacy rate was the highest in patients who received RPH+sMMH and decreased in the following order: patients who received RPH alone, MMH alone, procedure for prolapse and hemorrhoids (PPH) alone, and PPH+sMMH ( P < ...
September 1, 2017: Surgical Innovation
https://www.readbyqxmd.com/read/28905197/systemic-glyceryl-trinitrate-reduces-anal-sphincter-tone-is-there-a-therapeutic-indication
#16
C Connolly, S Tierney, P Grace
BACKGROUND: Nitric oxide (NO) has diverse roles as a biological messenger. [1] Topically applied nitrate donors cause relaxation of the internal anal sphincter (IAS) and facilitate healing of anal fissures [2,3]. Systemic nitrates are commonly used for the treatment of ischaemic heart disease, yet the effects of systemically administered nitrates on the smooth muscle of the IAS are unknown. AIM: Our aim was to test the hypothesis that systemically administered nitrates at a normal dose, cause inhibition of anal sphincter activity...
September 13, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28894786/methylene-blue-effectiveness-as-local-analgesic-after-anorectal-surgery-a-literature-review
#17
REVIEW
Dewi Fransiska, Wifanto Saditya Jeo, Yefta Moenadjat, Dewi Friska
BACKGROUND: Methylene blue (MB) has been found to have unique analgesic property through temporary disruption of sensory nerve conduction. In anorectal surgery, MB is widely used as a biologic stain but the analgesic effect has never been studied. Thus, a literature review completed with critical appraisal is required to find out its efficacy. METHODS: A review has been run to find out its efficacy. Literature search proceeded in database sites, namely, PubMed, EBSCO, Cochrane, Wiley, and ProQuest using the following keywords: "anorectal" OR "hemorrhoid" OR "anal fistula" OR "anal fissure" OR "anal abscess" OR "anal pruritus" AND "methylene blue" AND "analgesic"; then the critical appraisal and its implication were discussed...
2017: Advances in Medicine
https://www.readbyqxmd.com/read/28891011/treatment-of-chronic-anal-fissure-with-sacral-neuromodulation-a-pilot-study
#18
A Muñoz-Duyos, L Lagares-Tena, S Delgado-Rivilla
No abstract text is available yet for this article.
September 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28884323/-proctology-for-internists
#19
J Feisthammel, J Mössner
In proctology patients can often be helped with very little effort. With knowledge of the most common disease symptoms the treating physician can in many cases correctly recognize the cause of the complaints and initiate the appropriate therapy or arrange referral to a proctological institution. This article aims to briefly and succinctly present the most common diseases in proctology (e.g. mariscae, hemorrhoids, anal fissures, perianal venous thrombosis, abscesses and fistulas, condyloma acuminatum and anal carcinoma) and to provide the treating internist, even outside of gastroenterology, assistance with the management of proctological symptoms...
October 2017: Der Internist
https://www.readbyqxmd.com/read/28845119/a-novel-minimally-invasive-treatment-for-anal-fissure
#20
Alkiviadis F Pappas, Dimitrios K Christodoulou
No abstract text is available yet for this article.
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
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