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Chelvin Ca Sng, Jing Wang, Scott Hau, Hla Myint Htoon, Keith Barton
IMPORTANCE: The XEN-45 implant, a hydrophilic collagen implant which drains aqueous to the subconjunctival space, has not been investigated in the context of uveitic glaucoma. BACKGROUND: To determine the safety and efficacy of the XEN-45 collagen implant in eyes with uveitic glaucoma. DESIGN: Exploratory prospective case series PARTICIPANTS: Patients with medically uncontrolled uveitic glaucoma METHODS: Twenty four consecutive patients (mean age ± standard deviation [SD] = 45...
October 20, 2017: Clinical & Experimental Ophthalmology
Arif H K Pathan, Alexander Barash, Lawrence B Tena, Paul T Finger
PURPOSE: To provide a clinical description of the long-term outcome of a 103Pd plaque-irradiated ciliary body melanoma with extrascleral extension while attempting to preserve a subadjacent glaucoma filtering bleb. METHODS: A 75-year-old woman with pseudoexfoliative glaucoma for 17 years, 16 years status post argon laser trabeculoplasty, and 15 years status post trabeculectomy in the left eye, was diagnosed with an ipsilateral ciliary body melanoma with visible extrascleral extension...
September 23, 2017: European Journal of Ophthalmology
Jesse T McCann, Michael Engelbert
PURPOSE: To report a giant retinal pigment epithelium rip in a patient with a bullous retinal and choroidal detachment. METHODS: Case report with widefield imaging, fundus autofluorescence, and optical coherence tomography of the retina. RESULTS: This 62-year-old patient had a history of advanced glaucoma, trabeculectomy, blebitis, and endophthalmitis. He had cataract surgery 6 weeks before presentation. He was found to have a large bullous retinal and choroidal detachment with a large retinal pigment epithelium tear at the limit of the choroidal detachment...
October 2017: Retinal Cases & Brief Reports
Mika Harju, Sakari Suominen, Pasi Allinen, Eija Vesti
PURPOSE: To study the long-term outcome of deep sclerectomy with and without mitomycin-C (MMC) in patients with normal-tension glaucoma (NTG). METHODS: We prospectively analysed consecutive patients randomized to surgery performed either with (MMC group) or without (non-MMC) MMC. Surgery was considered totally successful if, after surgery, the preoperative intra-ocular pressure (IOP) level was reduced by 25% without medication, and a qualified success if medication was required to achieve the same limits...
August 21, 2017: Acta Ophthalmologica
R Siggel, T Dietlein
Complete atrophy of the filtration bleb is a very rare complication after trabeculectomy with mitomycin C and collagen matrix implant (Ologen®, Aeon Astron Corporation, Taipei, Taiwan). Clinically, the atrophy can present similar to blebitis. We report the case of a 71-year-old woman, in whom we resected the atrophic conjunctiva and reconstructed a filtration bleb using an amniotic membrane.
April 28, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Jennifer C Fan Gaskin, Sukhpal S Sandhu, Mark J Walland
IMPORTANCE: This study highlights the efficacy and safety of trabeculectomy in Victoria, Australia. BACKGROUND: Trabeculectomy is currently the gold standard in glaucoma surgery. However, its role has been increasingly questioned because of its associated risks and complications. This audit aimed to assess the efficacy and safety of trabeculectomy surgery in the state of Victoria, Australia. DESIGN: A cross-sectional, retrospective and voluntary statewide audit of trabeculectomy surgery by individual surgeons in 2012 with 24 months follow-up...
March 21, 2017: Clinical & Experimental Ophthalmology
Zhu Li Yap, You Chuen Chin, Judy Yu-Fen Ku, Tat Keong Chan, Gillian Teh, Monisha Esther Nongpiur, Tin Aung, Shamira A Perera
PURPOSE: Comparison of the demographic, ocular, systemic and microbiological characteristics of eyes with bleb related infection (BRI) and bleb related endophthalmitis (BRE). METHODS: Retrospective chart review of patients with BRI from January 1996-July 2013. Identification done via the center's longstanding endophthalmitis audit, BRI audit and laboratory database identifying all conjunctival swabs from blebs. Blebitis was defined as anterior segment inflammation with mucopurulent material in or around the bleb, with anterior chamber cells but no hypopyon...
2016: Clinical Ophthalmology
Thidarat Leeungurasatien, Preeyanuch Khunsongkiet, Kassara Pathanapitoon, Damrong Wiwatwongwana
BACKGROUND: To determine the incidence of early postoperative complications and associated factors after primary trabeculectomy in Thai glaucoma patients. DESIGN: This was a retrospective observational study performed in Chiang Mai University Hospital. PARTICIPANTS: One hundred and eighteen glaucoma patients participated in the study. METHODS: All glaucoma patients underwent primary trabeculectomy with mitomycin C (MMC) using fornix-based conjunctival flap technique between December 2011 and May 2013...
October 2016: Indian Journal of Ophthalmology
Jesse T McCann, Michael Engelbert
PURPOSE: To report a giant retinal pigment epithelium rip in a patient with a bullous retinal and choroidal detachment. METHODS: Case report with widefield imaging, fundus autofluorescence, and optical coherence tomography of the retina. RESULTS: This 62-year-old patient had a history of advanced glaucoma, trabeculectomy, blebitis, and endophthalmitis. He had cataract surgery 6 weeks before presentation. He was found to have a large bullous retinal and choroidal detachment with a large retinal pigment epithelium tear at the limit of the choroidal detachment...
August 9, 2016: Retinal Cases & Brief Reports
Anil K Mandal
PURPOSE: Relatively little data exist regarding the outcomes of children with primary infantile glaucoma presenting with acute corneal hydrops. The aim of our study was to determine the surgical outcome of children of infantile glaucoma who presented with acute corneal hydrops. METHODS: In total, 38 eyes of 31 consecutive children of infantile glaucoma presented with acute corneal hydrops who underwent primary combined trabeculotomy-trabeculectomy (CTT) by a single surgeon from January 1990 to December 2012 at the LV Prasad Eye Institute (LVPEI), a tertiary eye care centre in Southern India were enrolled in this retrospective study...
2016: PloS One
Petrina Tan, Raman Malhotra
The incidence of glaucoma worldwide is increasing. Often, these patients may also be referred to oculoplastic surgeons for either age-related problems or issues secondary to medical or surgical glaucoma treatment. Eyelid malpositions (ptosis or lid retraction) may occur after glaucoma filtration surgery or the use of prostaglandin analogues. We review the incidence and mechanisms of lid malpositions found in the literature. Surgical correction for these malpositions also requires careful consideration and should be tailored to the individual patient to avoid undesirable surgical outcomes...
November 2016: Survey of Ophthalmology
Akiko Narita, Jiro Seguchi, Fumio Shiraga
Paecilomyces lilacinus (P. lilacinus) is a rare cause of fungal scleritis. We herein report a case of P. lilacinus-induced scleritis following bleb-associated endophthalmitis after trabeculectomy that was successfully treated with surgical excision of the affected sclera in combination with antifungal medication. An 85-year-old female underwent trabeculectomy of the left eye. A dellen formed in the corneal periphery due to limbal elevation of the filtering bleb and progressed to an infectious corneal ulcer, leading to blebitis...
2015: Acta Medica Okayama
David A Solá-Del Valle, Bobeck S Modjtahedi, Dean Eliott, Lucy Q Shen
No abstract text is available yet for this article.
2015: International Ophthalmology Clinics
Sanaa A Yassin
Bleb-related infection (BRI) is one of the serious complications of glaucoma filtering surgery. This literature review is aimed at the evaluation of recent studies related to BRI. The review presented and discussed risk factors, and clinical and laboratory diagnosis emphasizing advances in diagnostic techniques to detect and distinguish the disease as well as to initiate immediate intensive antibacterial treatment. Clinical features of recognized prognostic factors of visual outcome were also presented. The studies showed that the prognosis of blebitis is usually good, unless infection has progressed to endophthalmitis that would signify a poorer prognosis...
March 2016: Acta Ophthalmologica
Elad Ben Artsi, Gabriel Katz, Michael Kinori, Joseph Moisseiev
PURPOSE: To portray the current scene of endophthalmitis in a multispecialty ophthalmology department regarding etiologies and treatment guidelines. METHODS: Retrospective chart review of all patients diagnosed with endophthalmitis or suspected endophthalmitis from 2009 to 2012. RESULTS: A total of 24 eyes were diagnosed with endophthalmitis or suspected endophthalmitis during a 4-year period. The etiologies included endogenous endophthalmitis (6), blebitis (3), Ahmed valve implantation (3, 2 of them with late infection), postcataract surgery (3), intravitreal injections (4), penetrating injury (2), and other surgical procedures (3)...
January 2016: European Journal of Ophthalmology
Dimitrios Tsoukanas, Paraskevi Xanthopoulou, Alexandros C Charonis, Panagiotis Theodossiadis, Gerasimos Kopsinis, Theodoros Filippopoulos
PURPOSE: To determine the safety and efficacy of fresh, human sclera allografts as a patch graft material in glaucoma drainage device (GDD) surgery. DESIGN: Retrospective, noncomparative, interventional, consecutive case series. SUBJECTS: All GDD cases operated between 2008 and 2013 in which fresh human corneoscleral rims were used immediately after the central corneal button was used for penetrating or endothelial keratoplasty. METHODS: Surgery was performed by 2 surgeons at 2 facilities...
July 2016: Journal of Glaucoma
Dmitry Yarovoy, Sunita Radhakrishnan, Terri-Diann Pickering, Andrew G Iwach
PURPOSE: To present the management and outcomes of blebitis in patients who underwent EX-PRESS Glaucoma Filtration Device (GFD) implantation. DESIGN: Retrospective case series. PARTICIPANTS: The study included 5 patients who developed blebitis following EX-PRESS GFD implantation. METHODS: Charts of all patients who underwent EX-PRESS GFD implantation at the Glaucoma Center of San Francisco between 2007 and 2013 were reviewed...
May 2016: Journal of Glaucoma
Cristos Ifantides, Oscar R Batlle, David Mushatt, Ramesh S Ayyala
PURPOSE: To report the first documented case of Nocardia exalbida blebitis. METHODS: A 57-year-old immunocompetent African American man with a long-standing history of open-angle glaucoma in both eyes treated with trabeculectomy presented with a diffusely hyperemic, thin, cystic, leaky bleb with no discharge in his left eye. The patient underwent bleb revision using an amniotic membrane patch graft followed by 1 month of antibiotics. He presented second time with an inflamed eye and brisk leakage and underwent a second bleb revision...
April 2015: Journal of Glaucoma
Eun-Ah Kim, Simon K Law, Anne L Coleman, Kouros Nouri-Mahdavi, JoAnn A Giaconi, Fei Yu, Ji-Woong Lee, Joseph Caprioli
PURPOSE: To report the incidence of late-onset bleb-related infections and to identify risk factors for bleb-related infections after trabeculectomy for the treatment of glaucoma. DESIGN: Retrospective case series. METHODS: Bleb-related infections were defined as blebitis, endophthalmitis, or blebitis with endophthalmitis. A total of 1959 eyes of 1423 patients who underwent trabeculectomy and who were followed for ≥1 year were included. RESULTS: Twenty-four eyes were diagnosed with bleb-related infections; 15 eyes were found to have blebitis and 9 eyes presented with endophthalmitis during the follow-up period of 5...
June 2015: American Journal of Ophthalmology
Jessica A Olayanju, Mohamed B Hassan, David O Hodge, Cheryl L Khanna
IMPORTANCE: Trabeculectomy is the surgical standard of care for patients with medically refractory glaucoma. The use of antimetabolite agents, such as mitomycin, has increased the rate of complications after trabeculectomy. OBJECTIVE: To determine the rate of trabeculectomy-related complications during a 25-year study. DESIGN, SETTING, AND PARTICIPANTS: For this retrospective, population-based study, we enrolled the residents of Olmsted County, Minnesota, who underwent a trabeculectomy from January 1, 1985, through December 31, 2010, at the Mayo Clinic and Olmsted Community Hospital...
May 2015: JAMA Ophthalmology
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