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Vena cava thrombosis

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https://www.readbyqxmd.com/read/29449161/ultrasound-training-in-surgical-critical-care-fellowship-a-survey-of-program-directors
#1
Thomas W Carver
OBJECTIVE: Surgical critical care (SCC) fellows are expected to receive training in critical care ultrasound (CCUS) but training is sporadic and there is no standardized curriculum to guide educators. Previous studies show wide variation in CCUS training during fellowship across specialties but SCC has been underrepresented. This study was performed to assess SCC program directors' views regarding CCUS during fellowship training. DESIGN: Adult SCC program directors were surveyed regarding the role of CCUS in fellowship training...
February 12, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29445486/aneurysm-of-the-inferior-vena-cava-with-thrombosis
#2
Masashi Inoue, Takeshi Sudo, Megumi Yamaguchi, Shingo Seo, Tatsuya Miyamoto, Toshihiro Misumi, Wataru Shimizu, Toshimitsu Irei, Takahisa Suzuki, Takashi Onoe, Yosuke Shimizu, Takao Hinoi, Hirotaka Tashiro
Inferior vena cava (IVC) aneurysms are extremely rare. Patients can be asymptomatic, have thrombosis, rupture, or pulmonary embolism. Thrombosis of the IVC aneurysm may mimic a retroperitoneal tumor. Surgical treatment of abdominal venous aneurysms with thrombosis is warranted and is necessary for the management of intraoperative bleeding and thrombosis.
February 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29445199/lack-of-t-bet-reduces-monocytic-interleukin-12-formation-and-accelerates-thrombus-resolution-in-deep-vein-thrombosis
#3
Tanja Schönfelder, Moritz Brandt, Sabine Kossmann, Tanja Knopp, Thomas Münzel, Ulrich Walter, Susanne H Karbach, Philip Wenzel
The role of leukocytes in deep vein thrombosis (DVT) resolution is incompletely understood. We determined how depletion of lysozyme positive (LysM + ) cells and a switched-off type 1 immune response influences thrombus resolution. DVT was induced in 12-week-old male mice by inferior vena cava (IVC) stenosis. Toxin mediated depletion of myeloid cells improved thrombus resolution in mice with Cre-inducible expression of the diphtheria toxin receptor in LysM + cells. This correlated with decreased CD45 + cells, a population shift of Gr-1 + to Gr-1 - CD11b + myelomonocytic cells (flow cytometry) and an increase in CC-chemokine ligand 2, interleukin-4 and interleukin-10 mRNA expressions...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29428534/midterm-result-of-endovascular-treatment-for-iliac-vein-compression-syndrome-from-a-single-center
#4
Chongqing Huang, Guanfeng Yu, Jingyong Huang
OBJECTIVE: To investigate the clinical effect of endovascular interventional treatment for iliac vein compression syndrome (IVCS). MATERIAL AND METHODS: The data of 68 patients with IVCS, underwent interventional treatment in our hospital, were analyzed retrospectively. Among these patients, 46 were complicated with lower extremity varicose veins. 65 patients underwent stent implantation, while 3 patients underwent simple balloon angioplasty. 14 patients were complicated with post-thrombotic syndrome (PTS) and 11patients with acute deep venous thrombosis (DVT)...
February 8, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29425537/-superior-vena-cava-thrombosis-or-stricture-secondary-to-implanted-central-venous-access-six-cases-of-endovascular-and-direct-surgical-treatment-in-cancer-patients
#5
J M Fichelle, V Baissas, S Salvi, J N Fabiani
Superior vena cava (SVC) stenosis or thrombosis is a well-known complication of central venous catheterization for endocavitary treatments, hemodialysis, or chemotherapy. In cancer patients, these SVC lesions are often symptomatic due to intimal damage and chemotherapy toxicity. We report our experience with six patients treated between 2007 and 2012 via an endovascular approach (n=5) or a direct surgical approach (n=1). All patients had SVC syndrome with facial edema, headache and upper limb edema. In three cases, the catheter was in place when the clinical symptoms occurred...
February 2018: Journal de Médecine Vasculaire
https://www.readbyqxmd.com/read/29419408/distinct-pathogenesis-of-pancreatic-cancer-microvesicle-associated-venous-thrombosis-identifies-new-antithrombotic-targets-in-vivo
#6
Konstantin Stark, Irene Schubert, Urjita Joshi, Badr Kilani, Parandis Hoseinpour, Manovriti Thakur, Petra Grünauer, Susanne Pfeiler, Tobias Schmidergall, Sven Stockhausen, Markus Bäumer, Sue Chandraratne, Marie-Luise von Brühl, Michael Lorenz, Raffaele Coletti, Sven Reese, Iina Laitinen, Sonja Maria Wörmann, Hana Algül, Christiane J Bruns, Jerry Ware, Nigel Mackman, Bernd Engelmann, Steffen Massberg
OBJECTIVE: Cancer patients are at high risk of developing deep venous thrombosis (DVT) and venous thromboembolism, a leading cause of mortality in this population. However, it is largely unclear how malignant tumors drive the prothrombotic cascade culminating in DVT. APPROACH AND RESULTS: Here, we addressed the pathophysiology of malignant DVT compared with nonmalignant DVT and focused on the role of tumor microvesicles as potential targets to prevent cancer-associated DVT...
February 1, 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29417408/comparative-outcomes-of-thrombocytopenic-acute-leukemic-patients-with-venous-thromboembolism-at-a-comprehensive-cancer-center
#7
Maliha Khan, Travis M Cox, Mohammed Nassif, Mohanad A Alzubaidi, Naveen Garg, Wei Qiao, Fleur M Aung, Thein Hlaing Oo, Cristhiam M Rojas-Hernandez
Patients with hematological malignancies often have severe thrombocytopenia, which poses problems when making thrombosis management decisions. A retrospective study was conducted to analyze the clinical outcomes associated with different management options in acute leukemic patients with thrombocytopenia (≤ 50 × 109/L) following an acute venous thromboembolic event. A total of 74 patients were divided into three treatment groups: observation only (n = 30); anticoagulation (n = 23); or inferior vena cava placement (n = 21)...
February 7, 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29415937/-portal-vein-thrombosis-associated-with-idiopathic-hypereosinophilic-syndrome
#8
Satoshi Kaito, Sakiko Harada, Masao Tsukada, Akira Kojima, Kanichi Iwama, Kazunari Yamada, Kouichi Kajiwara, Kentaro Morikawa, Keiki Shimizu, Yasuji Kozai, Hideki Koudo
A 35-year-old man who previously underwent splenectomy for hereditary spherocytosis at age 29 visited our hospital complaining of fatigue that had started 7 days ago and right upper abdominal pain. Laboratory data showed increased white blood cell and eosinophil count accompanied by severe transaminitis and clotting abnormalities. Computed tomography scan showed multiple embolisms in the portal vein, superior mesenteric vein, right pulmonary artery, and inferior vena cava. Severe liver damage presumably caused by portal vein thrombosis was also observed...
2018: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/29414798/fusion-to-human-serum-albumin-extends-the-circulatory-half-life-and-duration-of-antithrombotic-action-of-the-kunitz-protease-inhibitor-domain-of-protease-nexin-2
#9
William P Sheffield, Louise J Eltringham-Smith, Varsha Bhakta
BACKGROUND/AIMS: The Kunitz Protease Inhibitor (KPI) domain of protease nexin 2 (PN2) potently inhibits coagulation factor XIa. Recombinant KPI has been shown to inhibit thrombosis in mouse models, but its clearance from the murine circulation remains uncharacterized. The present study explored the pharmacokinetic and pharmacodynamic effects of fusing KPI to human serum albumin (HSA) in fusion protein KPIHSA. METHODS: Hexahistidine-tagged KPI (63 amino acids) and KPIHSA (656 amino acids) were expressed in Pichia pastoris yeast and purified by nickel-chelate chromatography...
February 1, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29407339/emergency-kidney-transplantation-in-recipients-with-iliocaval-thrombosis-using-splenic-vessel-anastomosis-after-splenectomy-a-case-series
#10
M Spaggiari, C Di Bella, P Di Cocco, S Furno, E Benedetti, I Tzvetanov
BACKGROUND: The external iliac vein is the standard site used for venous anastomosis in kidney transplantation. When a pre-transplantation diagnosis of iliocaval thrombosis is established, a different and suitable venous drainage for the renal outflow must be identified for successful transplant. METHODS: We report 4 cases of kidney transplantation, performed from 2004 to 2016, in recipients presenting with thrombosis of the inferior vena cava and iliac system needing, because of the lack of access for dialysis, urgent kidney transplantations...
January 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29401342/absent-inferior-vena-cava-leading-to-recurrent-lower-extremity-deep-vein-thrombosis-in-a-united-states-marine
#11
Sang Kim, Scott Kunkel, Kristin Browske
Introduction: Anomalies of the inferior vena cava (AIVC) are rare but well-recognized anatomic abnormalities that can lead to clinically significant deep vein thrombosis (DVT) in a subset of otherwise healthy patients. This report illustrates an uncommon congenital anomaly that military clinicians should consider when evaluating unprovoked DVT in young patients. Materials and Methods: Single case report and literature review. Results: We describe a case of a 24-yr-old United States Marine who presented with abdominal pain for 2 wk...
January 1, 2018: Military Medicine
https://www.readbyqxmd.com/read/29399535/deep-venous-thrombosis-in-pregnancy-incidence-pathogenesis-and-endovascular-management
#12
REVIEW
Paola Devis, M Grace Knuttinen
Deep venous thrombosis (DVT) during pregnancy is associated with high mortality, morbidity, and costs. Pulmonary embolism (PE), its most feared complication, is the leading cause of maternal death in the developed world. DVT can also result in long-term complications that include postthrombotic syndrome (PTS) adding to its morbidity. Women are up to 5 times more likely to develop DVT when pregnant. The current standard of care for this condition is anticoagulation. This review discusses the epidemiology, pathogenesis, prophylaxis and diagnosis of DVT during pregnancy, and then focuses on endovascular treatment modalities...
December 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/29394568/-which-should-be-treated-first-breast-cancer-or-uterine-myoma
#13
Keiko Hayashi, Mina Waraya, Takeyoshi Habiro, Satoshi Hosoya, Kouich Yamamoto, Norihiko Sengoku, Kazushige Hayakawa, Madoka Inukai, Masahiko Watanabe
The patient was a 51-year-old woman with a mass in the left breast.At the first presentation, she had abdominal distension and liver dysfunction.Mammography showed a category 5 mass in the left breast and a category 4, unstructured region in the right breast.Pathological examination revealed bilateral, invasive ductal carcinomas.Stage II B disease(clinical T2N1M0)was diagnosed in the left breast, and Stage I disease(clinical T1N0M0)was diagnosed in the right breast.Computed tomography revealed a massive uterine myoma compressing the inferior vena cava...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29392360/hepatic-sinusoidal-dilatation
#14
Giuseppe Brancatelli, Alessandro Furlan, Alberto Calandra, Marco Dioguardi Burgio
Hepatic sinusoidal dilatation refers to the enlargement of the hepatic capillaries. Most of the time this condition is caused by hepatic venous outflow obstruction, which results in vascular stasis and congestion of hepatic parenchyma. In this setting, hepatic sinusoidal dilatation can be related to pericardial disease, heart failure, compression or thrombosis of the hepatic veins or inferior vena cava (i.e., Budd-Chiari syndrome) or central veins/sinusoids involvement (i.e., sinusoidal obstruction syndrome)...
February 1, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29390472/upper-extremity-deep-vein-thrombosis-after-migration-of-peripherally-inserted-central-catheter-picc-a-case-report
#15
Kai Wang, Wenyan Sun, Xiaodong Shi
INTRODUCTION: Peripherally inserted central venous catheters (PICC) are widely used in cancer patients and ultrasound-guided PICC insertion could improve success rate. The tip position of the catheter should be located at the border of lower one-third of the superior vena cava (SVC) and cavo-atrial junction. The migration is malposition at the late stage after PICCs were inserted, and catheter malposition was associated with thrombosis and other complications.After patient's informed consent, we report a case of a 66-year-old male with twice catheter migrations resulting in thrombosis after being diagnosed with cardiac cancer...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29389674/inherited-factor-ii-deficiency-with-paradoxical-hypercoagulability-a-case-report
#16
Harold Watson, Ariel Perez, Kwabena Ayesu, Faisal Musa, Jose Sarriera, Mario Madruga, Steve J Carlan
: Congenital deficiency of factor II is a very rare autosomal recessive disorder that can result in a bleeding diathesis. Genotypically, individuals are either homozygous for a defective prothrombin gene or a compound heterozygote with different mutated prothrombin genes inherited from each parent. Phenotypically, it is characterized by either a low production of normal prothrombin or a near-normal production of dysfunctional prothrombin. Treatment is aimed at restoring normally functioning factor II circulating levels to sufficient concentration for hemostasis...
January 31, 2018: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/29376962/-acute-mesenteric-venous-thrombosis-in-pregnant-women-with-thrombophilia-and-doubled-inferior-vena-cava
#17
S A Chernyadiev, A Yu Leshchinskaya, N P Kuznetsov, A V Mikheev
No abstract text is available yet for this article.
2018: Khirurgiia
https://www.readbyqxmd.com/read/29359241/utility-of-retrievable-inferior-vena-cava-filters-a-systematic-literature-review-and-analysis-of-the-reasons-for-nonretrieval-of-filters-with-temporary-indications
#18
Zhongzhi Jia, Tyler A Fuller, J Mark McKinney, Ricardo Paz-Fumagalli, Gregory T Frey, David M Sella, Thuong Van Ha, Weiping Wang
OBJECTIVE: To investigate the use of retrievable inferior vena cava (IVC) filters in the current practice and analyze the causes of filter left in situ despite initial plans for retrieval. METHODS: A systematic search of all English-language studies of retrievable IVC filters was conducted, including clinical trials and observational studies published between January 1984 and March 2016. RESULTS: A total of 103 studies were identified, including 10 filter models in 20,319 patients...
January 22, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29349400/single-session-total-endovascular-iliocaval-reconstruction-with-stent-grafting-for-the-treatment-of-inferior-vena-cava-agenesis-and-concurrent-iliac-venous-aneurysm-rupture
#19
Jeffrey Forris Beecham Chick, Minhaj S Khaja, Steven Han, Kyle J Cooper, J Matthew Meadows, David M Williams
Iliac venous aneurysms are rare vascular abnormalities that may be manifested by abdominal masses, pelvic tenderness, or hypovolemia and may lead to rupture, thrombosis, pulmonary embolism, paradoxical embolism, or death. Inferior vena cava agenesis, like venous aneurysm, is an uncommon condition that may present with deep venous thrombosis. This report describes a patient with inferior vena cava agenesis and iliac venous aneurysm rupture treated with emergent iliocaval reconstruction and endovascular stent graft placement...
September 2017: Journal of Vascular Surgery Cases and Innovative Techniques
https://www.readbyqxmd.com/read/29337042/endovascular-recanalization-for-nonmalignant-obstruction-of-the-inferior-vena-cava
#20
Young Erben, Haraldur Bjarnason, Gudrun L Oladottir, Robert D McBane, Peter Gloviczki
OBJECTIVE: The aim of this study was to evaluate outcomes of endovascular recanalization of the inferior vena cava (IVC) and iliac veins with long-standing chronic venous obstruction caused by nonmalignant disease. METHODS: Medical records for 66 patients who underwent endovascular recanalization of the IVC with or without iliac veins from January 2001 to December 2014 at our medical center were retrospectively reviewed. Primary outcomes included morbidity and mortality; secondary outcomes included primary, primary assisted, and secondary patency and resolution of symptoms...
January 11, 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
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