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Vena cava thrombosis

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https://www.readbyqxmd.com/read/27893792/renal-cell-carcinoma-associated-with-xp11-2-translocation-tfe3-gene-fusions-clinical-features-treatments-and-prognosis
#1
Ning Liu, Zhen Wang, Weidong Gan, Lei Xiong, Baolei Miao, Xiancheng Chen, Hongqian Guo, Dongmei Li
To investigate the clinical characteristics, treatments and prognosis of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusions (Xp11.2 tRCC), the epidemiological features and treatment results of 34 cases of Xp11.2 tRCC, which were diagnosed by immunohistochemistry staining of TFE3 and fluorescence in situ hybridization at our center, were retrospectively reviewed. The 34 patients included 21 females and 13 males aged 3 to 64 years (median age: 27 years). Four patients were children or adolescents (<18 years of age), and 26 patients were young or middle-aged adults (18-45 years)...
2016: PloS One
https://www.readbyqxmd.com/read/27886952/complex-inferior-vena-cava-filter-retrieval-complicated-by-migration-of-filter-fragment-into-the-aorta-and-subsequent-distal-embolization
#2
Erica M Knavel, Michael A Woods, Mark G Kleedehn, Orhan S Ozkan, Paul F Laeseke
In 2005, a 48-year-old man with a spinal cord injury had an inferior vena cava filter placed for recurrent deep vein thrombosis and pulmonary embolism. He was referred for filter retrieval after a computed tomography scan demonstrated caval stenosis and 2 fractured filter arms, 1 in a pulmonary artery and 1 penetrating into the retroperitoneum and impinging on the aorta. During retrieval, 1 arm was inadvertently advanced into the aorta, and embolization of the arm occurred to the left profunda femoris artery...
December 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27886800/beh%C3%A3-et-s-disease-how-to-diagnose-and-treat-vascular-involvement
#3
REVIEW
Emire Seyahi
Behçet's disease is a multisystem disorder with unknown etiology and a unique geographic distribution. The disease is characterized by recurrent skin-mucosa lesions and sight-threatening panuveitis. Vascular involvement, which is more common and more severe among males, has also equally characteristic features such as affecting mostly veins, having a significant tendency for thrombosis, and running a relapsing course. Lower extremity vein thrombosis (LEVT) is the most frequent manifestation, followed by vena cava inferior thrombosis...
April 2016: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/27882061/the-long-term-outcomes-for-patients-with-budd-chiari-syndrome-caused-by-behcet-s-disease-a-case-series-on-the-results-from-cirrhosis-to-death
#4
Dondu Uskudar Cansu, Tuncer Temel, Adem Erturk, Timucin Kasifoglu, Berat Acu, Cengiz Korkmaz
BACKGROUND: Budd-Chiari syndrome, which is a rare complication of Behcet's disease, carries a high mortality rate. OBJECTIVES: The aim of the study was to present our long-term follow up experience with patients suffering from Budd-Chiari syndrome due to Behcet's disease. METHODS: The records of 402 patients with Behcet's disease were evaluated retrospectively. To facilitate detection of the long-term complications caused by Budd-Chiari syndrome, the patients were evaluated via physical examinations, laboratory tests, imaging modalities, and endoscopy results...
October 2016: Hepatitis Monthly
https://www.readbyqxmd.com/read/27876598/antithrombotic-activity-of-batroxase-a-metalloprotease-from-bothrops-atrox-venom-in-a-model-of-venous-thrombosis
#5
Anna L Jacob-Ferreira, Danilo L Menaldo, Marco A Sartim, Thalita B Riul, Marcelo Dias-Baruffi, Suely V Sampaio
BACKGROUND: Snake venoms are great sources of bioactive molecules, which may be used as models for new drugs. Toxins that interfere in hemostasis have received considerable attention over the years. OBJECTIVES: This study aimed at the evaluation of the antithrombotic activity of Batroxase, a P-I metalloprotease from Bothrops atrox venom, in an animal model of venous thrombosis. METHODS: The antithrombotic activity of Batroxase was tested in vivo in a model based on two factors of the Virchow's Triad: blood flow alterations (partial stenosis of the inferior vena cava), and vessel wall injury (10% ferric chloride for 5min), in comparison with sodium heparin (positive control) and saline (negative control)...
November 19, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27875796/development-of-extensive-inferior-vena-cava-thrombosis-due-to-the-ligation-of-a-large-mesenteric-caval-shunt-during-liver-transplantation-a-case-report
#6
Hideya Kamei, Yasuharu Onishi, Masatoshi Ishigami, Yoji Ishizu, Kojiro Suzuki, Yasuhiro Ogura
INSTRUCTION: Inferior vena cava (IVC) thrombosis can be a life-threatening complication after liver transplantation (LT). Although this complication is usually related to technical problems associated with vascular anastomosis, we report a case of IVC thrombosis which developed from a ligated large mesenteric-caval shunt. PRESENTATION OF CASE: A 35-year-old man underwent LT from a brain-dead donor for primary sclerosing cholangitis. Enhanced computed tomography (CT) before LT showed a huge collateral vessel of the inferior mesenteric vein (IMV) draining into the infra-renal IVC directly...
November 15, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27871206/brucellosis-and-thrombosis-of-the-inferior-vena-cava
#7
Kristina Rüegger, Philip Tarr, Konstantinos Karatolios, Jörg Humburg, Rolf Hügli, Christina Jeanneret
We describe the case of a 23-year old woman with a newly diagnosed thrombosis of the inferior vena cava associated with a Brucella melitensis infection. We suggest possible mechanisms leading to brucellosis-associated venous thrombosis and review 14 previously reported cases.
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November 22, 2016: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/27865097/etiology-and-treatment-of-acute-inferior-vena-cava-thrombosis
#8
REVIEW
Wanyin Shi, Joshua D Dowell
Inferior vena cava thrombosis (IVCT) is a rare but severe disease that is associated with a high rate of mortality. IVCT can be categorized into primary versus secondary thrombosis dependent upon the underlying pathophysiology. The diagnosis includes both clinical probability assessment as well as the imaging evaluation. The optimal therapeutic strategy remains the target of continued research. Although anticoagulation therapy remains fundamental in treating IVCT, its inherent limitations have led to the use of minimally invasive, endovascular treatment options, including transcatheter thrombolysis, mechanical thrombectomy or a combination of these techniques...
July 21, 2016: Thrombosis Research
https://www.readbyqxmd.com/read/27861176/low-cardiac-output-after-orthotopic-heart-transplant-secondary-to-large-inferior-vena-cava-thrombus-after-prothrombin-complex
#9
Kimberly Ann Pollock, Zeb McMillan, Gert Diederick Pretorius, Brett Cronin
Low cardiac output after orthotopic heart transplant (OHT) may be attributed to inadequate preload, vasodilation, and/or reduced inotropy. Inadequate preload because of an inferior vena cava (IVC) thrombus is a rare cause of low cardiac output and not frequently described in the literature. Although the use of prothrombin complex (PCC) has been associated with thrombus formation, its contribution to life-threatening IVC thrombosis has yet to be described. This case report describes the use of perioperative ultrasound in the diagnosis and management of a low cardiac output state induced by an IVC thrombus in an OHT recipient who received PCC...
November 17, 2016: A & A Case Reports
https://www.readbyqxmd.com/read/27858894/preoperative-deep-vein-thrombosis-in-patients-with-cervical-spondylotic-myelopathy-scheduled-for-spinal-surgery
#10
Le Liu, Yan-Bin Liu, Jian-Min Sun, Hai-Feng Hou, Chen Liang, Tao Li, Heng-Tao Qi
INTRODUCTION: The prevalence of deep vein thrombosis (DVT) and its risk factors in patients with cervical spondylotic myelopathy (CSM) before spinal surgery are poorly understood. We investigated this association with a retrospective cross-sectional study. PATIENTS CONCERNS: The study cohort consisted of all consecutive patients with CSM who were scheduled for spinal surgery at our institution from 2013 to 2015. DVT was defined as an intraluminal filling defect in a lower extremity vein identified by Doppler ultrasonography...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27855459/-port-catheter-associated-superior-vena-cava-syndrome-in-a-patient-with-rectum-cancer
#11
Nikolai Schuelper, Jakob von Herder, Antonius Flohr, Gerald Wulf, Sabine Blaschke
History and clinical findings | A 59-year-old man with metastasized rectum cancer presents at the interdisciplinary emergency care unit with a distinct cyanosis of his face. At that moment the patient himself is out of any complaints. Cyanosis is spreading from his face over his neck to both arms. During the last months he has been treated with folinic acid, 5-fluoruracil, irinotecan and aflibercept via a port-catheter. Except for smoking his further medical history is unremarkable. Examinations | CT-scan shows a port-catheter associated thrombosis with a consecutive superior vena cava syndrome (SCVS)...
November 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27853070/edoxaban-was-effective-for-the-treatment-of-deep-vein-thrombosis-and-pulmonary-thromboembolism-in-a-cancer-patient-with-antithrombin-iii-deficiency
#12
Hiroaki Kawano, Koji Maemura
A 57-year-old man with antithrombin III deficiency with deep vein thrombosis and pulmonary thromboembolism after surgery for colon cancer was managed with warfarin and inferior vena cava filtration. After starting chemotherapy for liver metastasis, the control of his prothrombin time-international normalized ratio in response to warfarin began to fluctuate. Warfarin was changed to edoxaban (an oral direct Factor Xa inhibitor), and he had no recurrence of venous thromboembolism or bleeding for approximately 1 year...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27849260/rare-complication-of-non-treated-abdominal-aortic-aneurysm-extensive-thrombus-in-right-cardiac-chambers
#13
Viviane Tiemi Hotta, David A Bluemke, Kamila Fernanda Staszko, Ana Neri Rodrigues Epitacio Pereira, Carlos Eduardo Rochitte
A 78-year-old patient presented with shortness of breath after falling down. Transthoracic echocardiogram showed an extensive thrombus in the right atrium (RA), extensive thrombosis of the inferior vena cava (IVC), and abdominal aortic aneurysm (AAA). A magnetic resonance confirmed the thrombosis of the RA extending to the IVC, which was apparently fused to the abdominal aortic aneurysm (compression? erosion?). This case illustrates a severe and rare complication of a non-treated AAA. There probably was IVC erosion by the aortic aneurysm, leading to blood stasis and extensive thrombosis of the IVC and right cardiac chambers...
October 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27847650/massive-thrombosis-of-the-right-atrium-extended-to-the-superior-vena-cava-at-the-diagnosis-of-acute-myeloid-leukemia
#14
Bienvenu Houssou, Gnon Gourou Orou-Guiwa, Rachida Habbal, Meryem Qachouh, Asmaa Quessar
Introduction. Venous thromboembolic disease is a common complication found in 8% of patients with acute myeloid leukemia. The location at the right atrium is exceptional. These last fifty years, only 6 cases of thrombosis of the atrium in the diagnosis of acute myeloid leukemia were published on PubMed search engine. Case Presentation. 35-year-old farmer, who had been admitted by emergency department for superior vena cava syndrome and had a hyperleukocytic AML with complex karyotype associated with a significant thrombosis of the right atrium, extended all along the superior vena cava...
2016: Case Reports in Cardiology
https://www.readbyqxmd.com/read/27813324/coagulation-factor-xi-vaccination-an-alternative-strategy-to-prevent-thrombosis
#15
Conghao Zhong, Li Zhang, Lei Chen, Li Deng, Rongxiu Li
BACKGROUND: Coagulation Factor XI (FXI) serves as a signal amplifier in the intrinsic coagulation pathway. Blockade of FXI by monoclonal antibodies or small molecule inhibitors inhibits thrombosis without causing severe bleeding, which is an inherent risk of currently available antithrombotic agents. OBJECTIVES: In this study, we designed an FXI vaccine and assessed its efficacy in inhibiting FXI activity and preventing thrombosis. METHODS: An FXI antigen was generated by fusing the catalytic domain of human FXI to the carboxyl terminus of the transmembrane domain of diphtheria toxin...
November 4, 2016: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/27807564/downhill-esophageal-varices-associated-with-central-venous-catheter-related-thrombosis-managed-with-endoscopic-and-surgical-therapy
#16
Joshua C Berkowitz, Sushma Bhusal, Deepak Desai, Maurice A Cerulli, Sumant Inamdar
Downhill esophageal varices are a rare cause of upper gastrointestinal hemorrhage. We present a case of downhill variceal bleeding due to superior vena cava thrombosis resulting from a prior central venous catheter. The patient was managed with endoscopic band ligation and later with surgical axillary vein to right atrium bypass grafting. Successful long-term resolution of varices was achieved at 1 year of follow-up. This is the longest follow-up described for combined endoscopic and surgical management in the existing literature for catheter-associated downhill varices...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27802848/a-case-of-renal-cell-carcinoma-with-an-extensive-inferior-vena-cava-thrombosis
#17
Majd Alfreijat
Renal cell carcinoma (RCC) is the most prevalent primary renal malignant neoplasm in adults. Most of the cases are usually found incidentally. It is commonly associated with venous thrombosis. We demonstrate a case of a RCC which was associated with an extensive thrombus that reached the upper part of the inferior vena cava (IVC). We also perform a brief literature review about the association between RCC and IVC thrombosis.
2016: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/27797848/invasive-thymoma-presenting-as-classic-superior-vena-cava-syndrome-a-case-of-venous-spread-metastasis
#18
Prasan Kumar Panda, Naveet Wig, Sanjeev Kumar, Sudheer Arava
The approach to an intrinsic cause of superior vena cava syndrome (SVCS) is usually difficult but rewarding. We report a case of a middle-aged man who presented with progressive oedema of the upper half of the body, dyspnoea, cough and weight loss for a 1-year duration. He was a non-smoker without prior hospitalisation. Chest radiography showed right-sided pleural effusion with an apparent normal superior mediastinum. Contrast-enhanced CT of the chest revealed a right atrial mass extending and completely obliterating to superior vena cava...
October 26, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27793623/bundling-of-reimbursement-for-inferior-vena-cava-filter-placement-resulted-in-significantly-decreased-utilization-between-2012-and-2014
#19
Roan J Glocker, Matthew J TerBush, Elaine L Hill, Joseph J Guido, Adam Doyle, Jennifer L Ellis, Kathleen Raman, Gary R Morrow, Michael C Stoner
BACKGROUND: On January 1, 2012, reimbursement for inferior vena cava filters (IVCFs) became bundled by the Centers for Medicare and Medicaid Services. This resulted in ICVF placement (CPT code 37191) now yielding 4.71 relative value units (RVUs), a decrease from 15.6 RVUs for placement and associated procedures (CPT codes 37620, 36010, 75825-26, 75940-26). Our hypothesis was that IVCF utilization would decrease in response to this change as other procedures had done once they had become bundled...
October 25, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27791258/femorally-inserted-central-venous-catheter-in-patients-with-superior-vena-cava-obstruction-choice-of-the-optimal-exit-site
#20
Jinghui Zhang, Siyuan Tang, Chengping Hu, Cailan Zhang, Lianxiang He, Xuebing Li, Jinnan Xiao
PURPOSE: This study assessed patient comfort and catheter indwelling time and decreased incidence of complications in patients with femorally inserted venous catheters (FIVCs) via different exit sites. METHODS: A group of 114 patients suffering from lung cancer complicated by superior vena cava obstruction (SVCO) underwent femoral insertion of venous catheters to facilitate chemotherapy infusion. Patients were divided into two groups: a novel (NOV) group (n = 59) with the FIVC exit site at the mid-thigh and a conventional (CON) group (n = 55) with the exit site at the groin...
October 26, 2016: Journal of Vascular Access
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