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https://www.readbyqxmd.com/read/28822753/the-genepattern-notebook-environment
#1
Michael Reich, Thorin Tabor, Ted Liefeld, Helga Thorvaldsdóttir, Barbara Hill, Pablo Tamayo, Jill P Mesirov
Interactive analysis notebook environments promise to streamline genomics research through interleaving text, multimedia, and executable code into unified, sharable, reproducible "research narratives." However, current notebook systems require programming knowledge, limiting their wider adoption by the research community. We have developed the GenePattern Notebook environment (http://www.genepattern-notebook.org), to our knowledge the first system to integrate the dynamic capabilities of notebook systems with an investigator-focused, easy-to-use interface that provides access to hundreds of genomic tools without the need to write code...
August 14, 2017: Cell Systems
https://www.readbyqxmd.com/read/28822228/computerized-neurocognitive-interventions-in-the-context-of-the-brain-training-controversy
#2
Rebeca Isabel García-Betances, María Fernanda Cabrera-Umpiérrez, María T Arredondo
This article presents, in the form of an analytic narrative review, a complete picture of the state-of-the-art, challenges, and perspectives in the field of information and communication technology (ICT)-based neurocognitive interventions for older adults. The narrative particularly focuses on applications aimed at mild cognitive impairment and similar age-related cognitive deficits, which are analyzed in the context of the brain training controversy. Clarifying considerations are provided about the nature and present extent of the brain training debate, regarding the possible influence it has on the support received by research and development initiatives dealing with innovative computerized neurocognitive interventions...
August 19, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/28821700/comparison-of-veterinary-drugs-and-veterinary-homeopathy-part-2
#3
P Lees, L Pelligand, M Whiting, D Chambers, P-L Toutain, M L Whitehead
Part 2 of this narrative review outlines the theoretical and practical bases for assessing the efficacy and effectiveness of conventional medicines and homeopathic products. Known and postulated mechanisms of action are critically reviewed. The evidence for clinical efficacy of products in both categories, in the form of practitioner experience, meta-analysis and systematic reviews of clinical trial results, is discussed. The review also addresses problems and pitfalls in assessing data, and the ethical and negative aspects of pharmacology and homeopathy in veterinary medicine...
August 19, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28821280/methods-for-medical-device-and-equipment-procurement-and-prioritization-within-low-and-middle-income-countries-findings-of-a-systematic-literature-review
#4
Karin Diaconu, Yen-Fu Chen, Carole Cummins, Gabriela Jimenez Moyao, Semira Manaseki-Holland, Richard Lilford
BACKGROUND: Forty to 70 % of medical devices and equipment in low- and middle-income countries are broken, unused or unfit for purpose; this impairs service delivery to patients and results in lost resources. Undiscerning procurement processes are at the heart of this issue. We conducted a systematic review of the literature to August 2013 with no time or language restrictions to identify what product selection or prioritization methods are recommended or used for medical device and equipment procurement planning within low- and middle-income countries...
August 18, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28821217/a-practice-based-theory-of-healing-through-therapeutic-touch-advancing-holistic-nursing-practice
#5
Mary Anne Hanley, Denise Coppa, Deborah Shields
For nearly 50 years, Therapeutic Touch (TT) has contributed to advancing holistic nursing practice and has been recognized as a uniquely human approach to healing. This narrative explores the development of a practice-based theory of healing through TT, which occurred between 2010 and 2016. Through the in-depth self-inquiry of participatory reflective dialogue in concert with constant narrative analysis, TT practitioners revealed the meaning of healing within the context of their TT practice. As the community of TT experts participated in an iterative process of small group and community dialogues with analysis and synthesis of emerging themes, the assumptions and concepts central to a theory of healing emerged, were clarified and verified...
August 1, 2017: Journal of Holistic Nursing: Official Journal of the American Holistic Nurses' Association
https://www.readbyqxmd.com/read/28820797/postoperative-renal-dysfunction-after-noncardiac-surgery
#6
Suvi T Vaara, Rinaldo Bellomo
PURPOSE OF REVIEW: The narrative review aims to discuss recent results and important knowledge gaps regarding acute kidney injury (AKI) in postoperative patients undergone major noncardiac surgery. RECENT FINDINGS: Postoperative AKI affects approximately one-fifth of patients after major surgery, but the incidence varies according to the type of surgery. Preexisting chronic kidney disease is a major risk factor for postoperative AKI. It carries a substantial risk for postoperative adverse outcomes, as well as long-term mortality and morbidity...
August 17, 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/28820757/flipping-the-nursing-classroom-without-flipping-out-the-students
#7
Victoria Anne Greenwood, Caroline Mosca
Flipping the class has been touted as a method of increasing student participation and improving learning outcomes. In this study, nursing students were introduced to the flipped classroom. They were instructed to listen to narrated PowerPoint presentations before class and be ready to participate in case studies that would enhance their understanding of important concepts. When comparing student test scores before and after flipping the classroom, we found a statistically significant increase of 8.04 points after the change in instruction...
August 17, 2017: Nursing Education Perspectives
https://www.readbyqxmd.com/read/28820665/size-matters-penis-size-and-sexual-position-in-gay-porn-profiles
#8
Joseph Brennan
This article combines qualitative and quantitative textual approaches to the representation of penis size and sexual position of performers in ten of the most visited gay pornography websites currently in operation. Specifically, in excess of 6,900 performer profiles sourced from ten commercial websites are analysed. Textual analysis of the profile descriptions is combined with a quantitative representation of disclosed penis size and sexual position, which is presented visually by two figures. The figures confirm that these sites generally market themselves as featuring penises that are extraordinarily large, and finds a sample-wide correlation between smaller penis sizes (5-6...
August 18, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28820605/body-sovereignty-and-body-liability-in-the-wake-of-an-obesity-epidemic-a-poststructural-analysis-of-the-soda-ban
#9
Sonia R Ivancic
Public discourse about the 2012 soda ban proposal and its eventual dissolution offers a useful context for interrogating how discursive processes constitute and regulate normality, risk, and obesity. Using poststructural sensibilities, I critique the soda ban and public discourse about it. Although architects of the soda ban and its proponents challenged the neoliberal narrative of free choice by self-governing citizens, their efforts were stymied by (1) arguments that offered a minimalist role for the state in regulating health, and (2) contemporary anxieties about losing the ability to self-determine what to let into the body...
August 18, 2017: Health Communication
https://www.readbyqxmd.com/read/28820515/the-role-of-oncology-nurses-in-discussing-clinical-trials
#10
Susan A Flocke, Elizabeth Antognoli, Barbara J Daly, Brigid Jackson, Sarah E Fulton, Tasnuva M Liu, Jessica Surdam, Sharon Manne, Neal J Meropol
PURPOSE/OBJECTIVES: To describe oncology nurses' experiences discussing clinical trials with their patients, and to assess barriers to these discussions.
. RESEARCH APPROACH: A qualitative study designed to elicit narratives from oncology nurses. 
. SETTING: Community- and academic-based oncology clinics throughout the United States.
. PARTICIPANTS: 33 oncology nurses involved in direct patient care in community-based and large hospital-based settings...
September 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28819920/-no-country-for-old-men-huxley-s-brave-new-world-and-the-value-of-old-age
#11
Maren Linett
This article inserts Aldous Huxley's Brave New World (1932) into a bioethical conversation about the value of old age and old people. Exploring literary treatments of bioethical questions can supplement conversations within bioethics proper, helping to reveal our existing assumptions and clear the way for more considered views; indeed, as Peter Swirski has argued, literary texts can serve as thought experiments that illuminate the ramifications of philosophical ideas. This essay examines the novel's representation of a society without old people in conjunction with ideas about aging and life narratives put forward by philosophers and bioethicists such as Ezekiel Emanuel, Gilbert Meilaender, and Alasdair MacIntyre...
August 17, 2017: Journal of Medical Humanities
https://www.readbyqxmd.com/read/28819494/functioning-and-disability-in-recent-research-from-cameroon-a-narrative-synthesis
#12
Minal Ray, Lorena Wallace, Lawrence Mbuagbaw, Lynn Cockburn
INTRODUCTION: People living with disabilities in Cameroon face many barriers to daily functioning and social participation. However, there is limited research on disabilities and their impact. We sought to examine the research related to disability from Cameroon. METHODS: We conducted a systematic review, bibliometric analysis, and narrative synthesis of research related to disability, functioning, and social participation from Cameroon published during 2005-2014...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28818558/current-and-emerging-pharmacotherapies-for-obesity-in-australia
#13
REVIEW
Samantha Hocking, Anthony Dear, Michael A Cowley
BACKGROUND: Obesity is a major issue in Australia and globally. Many individuals struggle to maintain weight loss with lifestyle modification, and adjunctive pharmacotherapy may help. Historically, there have been limited pharmacotherapies for managing obesity. In addition, previous treatments such as phentermine-fenfluramine, rimonabant and sibutramine were withdrawn due to safety issues, resulting in lingering safety concerns. METHODS: This is a narrative review of published data examining four new pharmacotherapy options for weight management in Australia...
August 14, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28818457/relationship-between-sleep-duration-and-childhood-obesity-systematic-review-including-the-potential-underlying-mechanisms
#14
R Felső, S Lohner, K Hollódy, É Erhardt, D Molnár
AIM: The prevalence of obesity is continually increasing worldwide. Determining risk factors for obesity may facilitate effective preventive programs. The present review focuses on sleep duration as a potential risk factor for childhood obesity. The aim is to summarize the evidence on the association of sleep duration and obesity and to discuss the underlying potential physiological and/or pathophysiological mechanisms. DATA SYNTHESIS: The Ovid MEDLINE, Scopus and Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched for papers using text words with appropriate truncation and relevant indexing terms...
July 25, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28818118/effects-of-age-and-stimulus-material-on-character-introductions-of-swedish-speaking-four-to-six-year-olds
#15
Josefin Lindgren
This study investigates effects of age on character introductions in the oral narratives of seventy-two monolingual Swedish-speaking four- to six-year-olds, comparing results from the Multilingual Assessment Instrument for Narratives (MAIN; Gagarina et al., 2012, 2015), and the Edmonton Narrative Norms Instrument (ENNI; Schneider et al., 2005). The proportion of appropriate referring expressions for introducing story characters clearly increases from age four to six. However, the children's performance is strongly stimulus-dependent...
August 18, 2017: Journal of Child Language
https://www.readbyqxmd.com/read/28817978/transcutaneous-electrical-nerve-stimulation-tens-as-an-adjunct-for-pain-management-in-perioperative-settings-a-critical-review
#16
Mark I Johnson
Surgical procedures are ever more complex. Day-case surgical loads are increasing and the length of hospital stays are reducing. Management of pain in perioperative settings remains a challenge. Expert panels recommend a multimodal approach which is often interpreted by medical practitioners as polypharmacy. There is variability in non-pharmacological interventions offered to patients, although transcutaneous electrical nerve stimulation (TENS) has been used since the 1970s. Recommendations from expert panels are inconsistent about the use of TENS in perioperative pain settings...
August 18, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28817953/the-evidence-base-for-interventions-targeting-individuals-with-work-related-ptsd-a-systematic-review-and-recommendations
#17
Iris Torchalla, Verena Strehlau
The purpose of this study was to summarize the evidence base for interventions targeting individuals with work-related posttraumatic stress disorder (PTSD), to make recommendations for clinicians and administrative decision makers involved in their rehabilitation, and to guide future research in this area. Particular attention was given to studies that were conducted in naturalistic clinical settings or in a workers' compensation claim context. Electronic searches of Cochrane Central Register of Controlled Trials, MEDLINE, PubMed, PsycINFO, CINAHL, PILOTS, and EMBASE identified 11 articles...
August 1, 2017: Behavior Modification
https://www.readbyqxmd.com/read/28817479/comparison-of-instructional-methods-for-screening-brief-intervention-and-referral-to-treatment-for-substance-use-in-nursing-education
#18
Sarah Knopf-Amelung, Heather Gotham, Araba Kuofie, Pamela Young, Ronalda Manney Stinson, Jolene Lynn, Kendra Barker, Jessica Hildreth
Most nursing programs lack curriculum on substance use. This project evaluated 3 didactic instructional methods for teaching baccalaureate nursing students about screening, brief intervention, and referral to treatment for substance use. In-person, asynchronous narrated slides and interactive online instructional methods were all effective in developing students' competency; however, active learning methods (in-person and interactive online course) were more effective in changing students' attitudes about their role in screening and intervening for drug use...
August 16, 2017: Nurse Educator
https://www.readbyqxmd.com/read/28817065/evaluation-and-treatment-of-mild-traumatic-brain-injury-the-role-of-neuropsychology
#19
REVIEW
Carolyn Prince, Maya E Bruhns
Awareness of mild traumatic brain injury (mTBI) and persisting post-concussive syndrome (PCS) has increased substantially in the past few decades, with a corresponding increase in research on diagnosis, management, and treatment of patients with mTBI. The purpose of this article is to provide a narrative review of the current literature on behavioral assessment and management of patients presenting with mTBI/PCS, and to detail the potential role of neuropsychologists and rehabilitation psychologists in interdisciplinary care for this population during the acute, subacute, and chronic phases of recovery...
August 17, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28816882/a-narrative-review-of-adherence-to-subarachnoid-hemorrhage-guidelines
#20
Paolo Gritti, Oluwaseun Akeju, Ferdinando L Lorini, Luigi A Lanterna, Carlo Brembilla, Federico Bilotta
Over the past 2 decades, a large number of guidelines for aneurysmal subarachnoid hemorrhage (aSAH) management have been proposed. The primary aim of these "evidence-based" guidelines is to improve the care of aSAH patients by summarizing and making current knowledge readily available to clinicians. However, an investigation into aSAH guidelines, their changes along time and their successful translation into clinical practice is still lacking.We performed a literature search of historical events and subarachnoid hemorrhage guidelines using the Entrez PubMed NIH, Embase, and Cochrane databases for articles published up to November of 2016...
August 14, 2017: Journal of Neurosurgical Anesthesiology
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