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https://www.readbyqxmd.com/read/29456930/review-of-the-evidence-for-the-management-of-co-morbid-tic-disorders-in-children-and-adolescents-with-attention-deficit-hyperactivity-disorder
#1
REVIEW
Michael O Ogundele, Hani F Ayyash
Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children and adolescents, with prevalence ranging between 5% and 12% in the developed countries. Tic disorders (TD) are common co-morbidities in paediatric ADHD patients with or without pharmacotherapy treatment. There has been conflicting evidence of the role of psychostimulants in either precipitating or exacerbating TDs in ADHD patients. We carried out a literature review relating to the management of TDs in children and adolescents with ADHD through a comprehensive search of MEDLINE, EMBASE, CINAHL and Cochrane databases...
February 8, 2018: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/29450987/habit-tic-cough-presentation-and-outcome-with-simple-reassurance
#2
EDITORIAL
Angela Zacharasiewicz, Michael D Shields
No abstract text is available yet for this article.
March 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29449151/multiphase-evaluation-of-contrast-enhanced-endoscopic-ultrasonography-in-the-diagnosis-of-pancreatic-solid-lesions
#3
Takuya Ishikawa, Yoshiki Hirooka, Hiroki Kawashima, Eizaburo Ohno, Kiyotaka Hashizume, Kohei Funasaka, Masanao Nakamura, Ryoji Miyahara, Osamu Watanabe, Masatoshi Ishigami, Hidemi Goto
BACKGROUND/OBJECTIVES: Time-intensity curve (TIC) under contrast-enhanced EUS (CE-EUS) allows continuous and quantitative evaluation of targeted area in the pancreas. However, TIC is not always available and the procedure is complicated. We aimed to propose a simplified method by evaluating multiple phases of CE-EUS in the diagnosis of pancreatic solid lesions. METHODS: We retrospectively reviewed 210 patients with pancreatic solid lesions including 142 with pancreatic ductal cancer (PDAC), 31 with pancreatic neuroendocrine neoplasm, 13 with solid pseudopapillary neoplasm and 24 with mass-forming pancreatitis who underwent CE-EUS and achieved final diagnoses...
February 9, 2018: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/29448994/automatic-untargeted-metabolic-profiling-analysis-coupled-with-chemometrics-for-improving-metabolite-identification-quality-to-enhance-geographical-origin-discrimination-capability
#4
Lu Han, Yue-Ming Zhang, Jing-Jing Song, Mei-Juan Fan, Yong-Jie Yu, Ping-Ping Liu, Qing-Xia Zheng, Qian-Si Chen, Chang-Cai Bai, Tao Sun, Yuan-Bin She
Untargeted metabolic profiling analysis is employed to screen metabolites for specific purposes, such as geographical origin discrimination. However, the data analysis remains a challenging task. In this work, a new automatic untargeted metabolic profiling analysis coupled with a chemometric strategy was developed to improve the metabolite identification results and to enhance the geographical origin discrimination capability. Automatic untargeted metabolic profiling analysis with chemometrics (AuMPAC) was used to screen the total ion chromatographic (TIC) peaks that showed significant differences among the various geographical regions...
February 10, 2018: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29448805/differentiating-skull-base-chordomas-and-invasive-pituitary-adenomas-with-conventional-mri
#5
Ankang Gao, Jie Bai, Jingliang Cheng, Xiao Cheng, Shujian Li, Zanxia Zhang, Yong Zhang
Background It is difficult to distinguish between invasive pituitary adenomas (IPAs) and skull base chordomas based on tumor location and clinical manifestations. Purpose To investigate the value of the apparent diffusion coefficient (ADC), T2-weighted (T2W) imaging, and dynamic contrast enhancement (DCE) in differentiating skull base chordomas and IPAs. Material and Methods Data for 21 patients with skull base chordomas and 27 patients with IPAs involving the paranasal sinus were retrospectively reviewed, and all diagnoses were pathologically confirmed...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29440145/the-fact-inhibitor-cbl0137-synergizes-with-cisplatin-in-small-cell-lung-cancer-by-increasing-notch1-expression-and-targeting-tumor-initiating-cells
#6
Sarmishtha De, Daniel J Lindner, Claire Coleman, Gary Wildey, Afshin Dowlati, George R Stark
Traditional treatments of small cell lung cancer (SCLC) with cisplatin, a standard of care therapy, spare the tumor-initiating cells (TIC) that mediate drug resistance. Here we report a novel therapeutic strategy that preferentially targets TIC in SCLC in which cisplatin is combined with CBL0137, an inhibitor of the histone chaperone facilitates chromatin transcription (FACT), which is highly expressed in TIC. Combination of cisplatin and CBL0137 killed patient-derived and murine SCLC cell lines synergistically...
February 13, 2018: Cancer Research
https://www.readbyqxmd.com/read/29435830/continuous-production-of-isomalto-oligosaccharides-by-thermo-inactivated-cells-of-aspergillus-niger-j2-with-coarse-perlite-as-an-immobilizing-material
#7
Zhihua Huang, Zhihong Li, Yongjian Su, Yongfeng Zhu, Wei Zeng, Guiguang Chen, Zhiqun Liang
The coarse perlite 40-80 mesh was selected as an immobilizing material and put into a packed bed reactor (PBR) to continuously convert maltose to isomalto-oligosaccharides (IMOs). The PBR was prepared by mixing the thermo-inactivated cells (TIC) from Aspergillus niger J2 strain with the coarse perlite, then the mixture was put into an overpressure-resistant column. Compared with diatomite 40-80 mesh and thin perlite 80-120 mesh in PBR, coarse perlite was chosen as the best filtration aid, when the ratio of coarse perlite versus TIC was 1:1...
February 13, 2018: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/29433810/the-nosology-of-tardive-syndromes
#8
Karen Frei, Daniel D Truong, Stanley Fahn, Joseph Jankovic, Robert A Hauser
Since the original description of side effects of neuroleptics, different terminologies and definitions for tardive dyskinesia (TD) and tardive syndrome (TS) have been used by different authors, and often these two terms have been used interchangeably. This paper proposes a nosology designed to define and clarify various terms and phenomenologies within the TS spectrum. We propose to use the term tardive dyskinesia to refer to the original description of repetitive and complex oral-buccal-lingual (OBL) movements, as well as to the analogous repetitive movements that can appear in the limbs, trunk, or pelvis...
February 6, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29422931/treatment-of-children-and-adolescents-with-attention-deficit-hyperactivity-disorder-and-or-tourette-s-disorder-with-clonidine-extended-release
#9
Sung Woo Joo, Hyo-Won Kim
We aimed to assess the effectiveness and safety of clonidine extended release (ER) treatment in Korean youth with ADHD and/or Tourette's disorder. We retrospectively reviewed the medical records of 29 children and adolescents treated with clonidine ER. The effectiveness were retrospectively measured at baseline and after 4 and 12 weeks based on the Clinical Global Impression-Severity (CGI-S) and Clinical Global Impression-Improvement (CGI-I) scores. Safety was evaluated at each visit based on spontaneous reports from the subjects or from their parents/guardians...
January 2018: Psychiatry Investigation
https://www.readbyqxmd.com/read/29419772/effect-of-c-and-n-addition-on-thermoelectric-properties-of-tinisn-half-heusler-compounds
#10
Hwan Soo Dow, Woo Sik Kim, Weon Ho Shin
We investigated the thermoelectric properties of the ternary half-Heusler compound, TiNiSn, when introducing C and N. The addition of C or N to TiNiSn leads to an enhanced power factor and a decreasing lattice thermal conductivity by point defect phonon scattering. The thermoelectric performances of TiNiSn alloys are significantly improved by adding 1 at. % TiN, TiC, and figure of merit (ZT) values of 0.43 and 0.34, respectively, can be obtained at 723 K. This increase in thermoelectric performance is very helpful in the commercialization of thermoelectric power generation in the mid-temperature range...
February 8, 2018: Materials
https://www.readbyqxmd.com/read/29412384/thyroglobulin-levels-before-radioactive-iodine-therapy-and-dynamic-risk-stratification-after-1-year-in-patients-with-differentiated-thyroid-cancer
#11
Leonardo Bandeira, Rosália do Prado Padovani, Ana Luiza Ticly, Adriano Namo Cury, Nilza Maria Scalissi, Marília Martins Silveira Marone, Carolina Ferraz
OBJECTIVES: We sought to assess the relationship between stimulated thyroglobulin (sTg) before radioactive iodine therapy (RIT), and the dynamic risk stratification 1 year after treatment, and to establish the utility of the sTg as a predictor of response to therapy in these patients. A retrospective chart review of patients with differentiated thyroid cancer (DTC) who underwent RIT after surgery and were followed for at least 1 year, was carried out. SUBJECTS AND METHODS: Patients were classified according to the dynamic risk stratification 1 year after initial treatment...
December 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29409461/factor-structure-and-psychometric-properties-of-the-english-version-of-the-trier-inventory-for-chronic-stress-tics-e
#12
Katja Petrowski, Sören Kliem, Michael Sadler, Alicia E Meuret, Thomas Ritz, Elmar Brähler
BACKGROUND: Demands placed on individuals in occupational and social settings, as well as imbalances in personal traits and resources, can lead to chronic stress. The Trier Inventory for Chronic Stress (TICS) measures chronic stress while incorporating domain-specific aspects, and has been found to be a highly reliable and valid research tool. The aims of the present study were to confirm the German version TICS factorial structure in an English translation of the instrument (TICS-E) and to report its psychometric properties...
February 6, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29407718/neurocognitive-correlates-of-treatment-response-in-children-with-tourette-s-disorder
#13
Susanna W Chang, Joseph F McGuire, John T Walkup, Douglas W Woods, Lawrence Scahill, Sabine Wilhelm, Alan L Peterson, James Dziura, John Piacentini
This paper examined neurocognitive functioning and its relationship to behavior treatment response among youth with Tourette's Disorder (TD) in a large randomized controlled trial. Participants diagnosed with TD completed a brief neurocognitive battery assessing inhibitory functions, working memory, and habit learning pre- and post-treatment with behavior therapy (CBIT, Comprehensive Behavioral Intervention for Tics) or psychoeducation plus supportive therapy (PST). At baseline, youth with tics and Attention Deficit Hyperactivity Disorder (ADHD) exhibited some evidence of impaired working memory and simple motor inhibition relative to youth with tics without ADHD...
March 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29405921/benchmarking-treatment-response-in-tourette-s-disorder-a-psychometric-evaluation-and-signal-detection-analysis-of-the-parent-tic-questionnaire
#14
Emily J Ricketts, Joseph F McGuire, Susanna Chang, Deepika Bose, Madeline M Rasch, Douglas W Woods, Matthew W Specht, John T Walkup, Lawrence Scahill, Sabine Wilhelm, Alan L Peterson, John Piacentini
This study assessed the psychometric properties of a parent-reported tic severity measure, the Parent Tic Questionnaire (PTQ), and used the scale to establish guidelines for delineating clinically significant tic treatment response. Participants were 126 children ages 9 to 17 who participated in a randomized controlled trial of Comprehensive Behavioral Intervention for Tics (CBIT). Tic severity was assessed using the Yale Global Tic Severity Scale (YGTSS), Hopkins Motor/Vocal Tic Scale (HMVTS) and PTQ; positive treatment response was defined by a score of 1 (very much improved) or 2 (much improved) on the Clinical Global Impressions - Improvement (CGI-I) scale...
January 2018: Behavior Therapy
https://www.readbyqxmd.com/read/29405696/mining-a-kr%C3%A3-hnke-pyridine-library-for-anti-arenavirus-activity
#15
Pedro O Miranda, Beatrice Cubitt, Nicholas T Jacob, Kim D Janda, Juan Carlos de la Torre
Several arenaviruses cause hemorrhagic fever (HF) disease in humans and represent important public health problems in their en-demic regions. In addition, evidence indicates that the worldwide-distributed prototypic arenavirus lymphocytic choriomeningitis virus is a neglected human pathogen of clinical significance. There are no licensed arenavirus vaccines and current anti-arenavirus therapy is limited to an off-label use of ribavirin that is only partially effective. Therefore, there is an unmet need for novel therapeu-tics to combat human pathogenic arenaviruses, a task that will be facilitated by the identification of compounds with anti-arenaviral activity that could serve as probes to identify arenavirus-host interactions suitable for targeting, as well as lead com-pounds to develop future anti-arenaviral drugs...
February 6, 2018: ACS Infectious Diseases
https://www.readbyqxmd.com/read/29402367/-continuous-contrast-enhanced-ultrasound-applied-to-acute-kidney-injury-caused-by-sepsis-a-diagnostic-clinical-study
#16
Junyi Wang, Xinjing Gao, Dong Wang, Zhiyong Wang, Zhibo Li, Dong Liu, Lei Xu
OBJECTIVE: To evaluate the diagnostic value of contrast-enhanced ultrasound in acute kidney injury (AKI) caused by sepsis. METHODS: The sepsis patients admitted to intensive care unit of Tianjin Third Central Hospital from January 2015 to June 2017 were enrolled. All of the patients were completed the 6-hour Bundle treatment and the bilateral renal contrast-enhanced ultrasound within 24 hours, and the peak signal intensity (PSI), peak intensity time (PIT), wash internal rate (WIR) and renal function parameters were measured at the same time...
February 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29398548/comparison-of-growth-kinetics-between-static-and-dynamic-cultures-of-human-induced-pluripotent-stem-cells
#17
Yuma Kato, Mee-Hae Kim, Masahiro Kino-Oka
Understanding the fundamental mechanisms that govern the growth kinetics of human induced pluripotent stem cells (hiPSCs) contributes to culture design strategies to improve large-scale production. Two hiPSC lines (Tic and 253G1) were cultured under static and dynamic suspension conditions, and growth kinetics were compared during early (24-48 h), middle (48-72 h), and late (72-96 h) stages. In 2D static culture, similar growth profiles were observed for both hiPSC lines. However, there were significant differences in growth profile patterns and aggregate morphologies between hiPSC lines grown in 3D static and dynamic cultures...
February 2, 2018: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/29397675/risperidone-related-raynaud-s-phenomenon-an-adolescent-case
#18
Serkan Güneş, Özalp Ekinci, Halenur Teke, Veli Yıldırım
Raynaud's phenomenon is a recurrent vasospastic condition with reducing in peripheral blood flow due to cold, or emotional stress. White, blue and red discolorations occur during the attacks. Serotonin reuptake inhibitors, psychostimulants, and aripiprazole are reported to be related with Raynaud's phenomenon. Risperidone is an atypical antipsychotic drug with dopaminergic and serotonergic effects. In children and adolescents, risperidone is used for bipolar disorder, tic disorders, conduct disorder, schizophrenia, symptoms of irritability and self-mutilation...
February 28, 2018: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29392455/the-moves-motor-tic-obsessions-and-compulsions-vocal-tic-evaluation-survey-cross-cultural-evaluation-of-the-french-version-and-additional-psychometric-assessment
#19
Isabelle Jalenques, Candy Guiguet-Auclair, Philippe Derost, Pauline Joubert, Louis Foures, Andreas Hartmann, Julia Muellner, Fabien Rondepierre
INTRODUCTION: The Motor tic, Obsessions and compulsions, Vocal tic Evaluation Survey (MOVES) is a self-report scale suggested as a severity scale for tics and related sensory phenomena observed in Gilles de la Tourette syndrome (GTS) and recommended as a screening instrument by the Committee on Rating Scale Development of the International Parkinson's Disease and Movement Disorder Society. OBJECTIVES: To cross-culturally adapt a French version of the MOVES and to evaluate its psychometric properties...
February 1, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29380849/association-of-long-term-adherence-to-the-mind-diet-with-cognitive-function-and-cognitive-decline-in-american-women
#20
A M Berendsen, J H Kang, E J M Feskens, C P G M de Groot, F Grodstein, O van de Rest
OBJECTIVES: There is increasing attention for dietary patterns as a potential strategy to prevent cognitive decline. We examined the association between adherence to a recently developed Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet with cognitive function and cognitive decline, taking into account the interaction between the apolipoprotein E ε4 genotype and the MIND diet. DESIGN: Population-based prospective cohort study. PARTICIPANTS: A total of 16,058 older women aged 70 and over from the Nurses' Health Study...
2018: Journal of Nutrition, Health & Aging
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