Christine M Baugh, Julie M Stamm, David O Riley, Brandon E Gavett, Martha E Shenton, Alexander Lin, Christopher J Nowinski, Robert C Cantu, Ann C McKee, Robert A Stern
Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative disease thought to be caused, at least in part, by repetitive brain trauma, including concussive and subconcussive injuries. It is thought to result in executive dysfunction, memory impairment, depression and suicidality, apathy, poor impulse control, and eventually dementia. Beyond repetitive brain trauma, the risk factors for CTE remain unknown. CTE is neuropathologically characterized by aggregation and accumulation of hyperphosphorylated tau and TDP-43...
June 2012: Brain Imaging and Behavior