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https://www.readbyqxmd.com/read/28642683/object-phobia-and-altered-rhoa-signaling-in-amygdala-of-mice-lacking-rich2
#1
Tasnuva Sarowar, Stefanie Grabrucker, Tobias M Boeckers, Andreas M Grabrucker
RICH2 knockout (RICH2 KO) mice exhibit neophobia in the novel object test. To gain further insight into their anxiety-related phenotype, we subjected these mice to additional behavioral tests to elucidate whether the behavioral abnormality in these mice is a consequence of reduced exploratory motivation, and whether the neophobia is linked specifically to objects or also present for other modalities. RICH2 KO mice engage in normal exploration in a novel environment, suggesting that the anxiety-related phenotype is not due to reduced exploratory drive...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/28642079/common-and-distinct-brain-networks-underlying-panic-and-social-anxiety-disorders
#2
REVIEW
Yong-Ku Kim, Ho-Kyoung Yoon
Although panic disorder (PD) and phobic disorders are independent anxiety disorders with distinct sets of diagnostic criteria, there is a high level of overlap between them in terms of pathogenesis and neural underpinnings. Functional connectivity research using resting-state functional magnetic resonance imaging (rsfMRI) shows great potential in identifying the similarities and differences between PD and phobias. Understanding common and distinct networks between PD and phobic disorders is critical for identifying both specific and general neural characteristics of these disorders...
June 19, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28638212/choking-phobia-an-uncommon-phobic-disorder-treated-with-behavior-therapy-a-case-report-and-review-of-the-literature
#3
Swapnajeet Sahoo, Nandita Hazari, Susanta Kumar Padhy
Choking phobia is a relatively uncommon phobic disorder which is often encountered by otorhinolaryngologists and referred to psychiatrists as a cause of psychogenic dysphagia. If not diagnosed early and treated appropriately, it can have severe detrimental effects on the physical and psychological health of an individual. We present a case of a 20 year old female who presented with choking phobia and was treated with behavior therapy. Additionally, we discuss the differential diagnosis and treatment strategies of this rare anxiety disorder...
December 25, 2016: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28636768/driving-aggression-and-anxiety-intersections-assessment-and-interventions
#4
Heidi M Zinzow, Stephanie M Jeffirs
OBJECTIVE: Driving aggression and anxiety are significant contributors to risky driving and motor vehicle crashes (MVCs), which are leading causes of U.S. morbidity and mortality. Even though aggression and anxiety can be conceptualized as related features of the fight-or-flight response, literature on these topics has not been integrated. Driving aggression and anxiety are also transdiagnostic constructs that span multiple psychiatric disorders. Assessment and treatment of these complex problems must be understood to reduce the public health burden of MVCs...
June 21, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28622552/fornix-microalterations-associated-with-early-trauma-in-panic-disorder
#5
Seung-Taek Yu, Kang-Soo Lee, Sang-Hyuk Lee
BACKGROUND: It is well accepted that panic disorder (PD) is associated with early trauma, and that the limbic systems are one of the main structures involved in PD pathophysiology. However, previous studies have not addressed the relationship between early trauma and major limbic white-matter (WM) structures in PD. METHODS: Participants enrolled in the study consisted of 53 right-handed patients with PD and 21 healthy controls (HC). The Early Trauma Inventory Self Report-Short Form (ETISR-SF), Anxiety Sensitivity Inventory-Revised (ASI-R), and the Albany Panic and Phobia Questionnaire (APPQ) were applied in the study...
May 30, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28622045/age-related-characteristics-of-outpatients-with-anxiety-disorders-the-leiden-routine-outcome-monitoring-study
#6
Anke Schat, Martijn S van Noorden, Therese van Amelsvoort, Erik J Giltay, Nic J A van der Wee, Marc J Noom, Robert R J M Vermeiren, Frans G Zitman
OBJECTIVE: It has been hypothesised that clinically important age-related differences between adults with anxiety disorders exist; this study aims to elucidate these differences. METHODS: We analysed data from 1950 outpatients diagnosed with DSM-IV-TR anxiety disorders treated at a Dutch hospital or affiliated mental healthcare centres. Three age-groups (young- (18-25; n = 435), mid- (26-40; n = 788) and older adult (41-65; n = 727)) were compared with regard to social demographic characteristics, diagnostic characteristics, anxiety symptom profile, general psychiatric symptom profile and generic health status, in addition, linear analyses were carried out with age as a continuous variable...
June 16, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28618768/psychosocial-functioning-in-pediatric-patients-with-pectus-excavatum-and-pectus-carinatum
#7
Aliye Tuğba Bahadir, Pınar Kuru Bektaşoğlu, Aylin Çakiroğlu Eser, Ceyda Afacan, Mustafa Yüksel
BACKGROUND/AIM: Pectus excavatum and pectus carinatum are the most commonly seen anterior chest wall deformities. Recent studies reveal that minimal invasive repair of pectus deformities improves the quality of life. Our aim is to assess the psychosocial functioning and sociodemographic characteristics of pediatric patients with pectus deformities and evaluate the differences between patients operated on with minimal invasive repair techniques and nonoperated patients. MATERIALS AND METHODS:  Thirty-two patients with pectus deformities who were operated on 6 months or more before and 31 nonoperated patients participated in the study...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28617373/-a-psychological-content-of-social-phobia-syndrome
#8
O A Sagalakova, D V Truevtsev, I Ya Stoyanova
AIM: To perform a psychological analysis of social phobia syndrome. The subject area of research is the structure of mental activity and behavior in social activity. MATERIAL AND METHODS: The study included 32 patients with symptoms of social phobia (ICD-10 F40.1) and 29 healthy people (controls). A complex of psychological methods (questionnaires; pathopsychological experiment) was used. RESULTS AND CONCLUSION: Early maladaptive schemes and a tendency to mental rigidity can be a premorbid basis of the syndrome...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28607641/lessons-learned-from-the-study-of-masturbation-and-its-comorbidity-with-psychiatric-disorders-in-children-the-first-analytic-study
#9
Ashraf Tashakori, Atefeh Safavi, Sorour Neamatpour
BACKGROUND: The main source of information about children's masturbation is more on the basis of case reports. Due to the lack of consistent and accurate information. OBJECTIVE: This study aimed to determine prevalence and underlying factors of masturbation and its comorbidity with psychiatric disorders in children. METHODS: In this descriptive-analytical study, among the children referred to the Pediatrics Clinic of Psychiatric Ward, Golestan Hospital, Ahvaz, Southwest Iran, 98 children were selected by convenience sampling in 2014...
April 2017: Electronic Physician
https://www.readbyqxmd.com/read/28601111/allometric-control-of-affective-fluctuations-in-early-adolescents-their-association-with-anxiety-symptoms-and-temperament-traits
#10
Aina Fiol-Veny, Alejandro De la Torre-Luque, Maria Balle, Xavier Bornas
Many physiological systems are multistable, i.e. they operate at different time scales under an allometric control process. The multistability of affective fluctuations has been clearly illustrated in a sample of adults, but little is known about their dynamics in adolescents. The main aim of this study was to determine whether affective fluctuations in adolescents show multistability and to explore their relationship with anxiety symptomatology and temperamental factors. Twenty-five early adolescents self-reported their daily mood, anxiety and worry levels twice a day over a 100-day period...
July 2017: Nonlinear Dynamics, Psychology, and Life Sciences
https://www.readbyqxmd.com/read/28599192/psychophysiological-and-self-reported-reactivity-associated-with-social-anxiety-and-public-speaking-fear-symptoms-effects-of-fear-versus-distress
#11
Georgia Panayiotou, Maria Karekla, Dora Georgiou, Elena Constantinou, Michaela Paraskeva-Siamata
This study examines psychophysiological and subjective reactivity to anxiety-provoking situations in relation to social anxiety and public speaking fear. We hypothesized that social anxiety symptoms would be associated with similar reactivity across types of imaginary anxiety scenes and not specifically to social anxiety-related scenes. This would be attributed to co-existing depression symptoms. Public speaking fear was expected to be associated with more circumscribed reactivity to survival-threat scenes, due to its association with fearfulness...
June 1, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28593598/brief-report-macrocephaly-phenotype-and-psychiatric-comorbidity-in-a-clinical-sample-of-mexican-children-and-adolescents-with-autism-spectrum-disorders
#12
Lilia Albores-Gallo, Laura Fritsche-García, Arturo Pabel Miranda-Aguirre, Montserrat Avila-Acosta
Autism spectrum disorders (ASD) may present with macrocephaly. Few studies have analyzed the association with psychiatric comorbidity. Participants were 94 children with any ASD with an age range from 2 to 16 years (Mdn 6 years), 82% were boys. It was found that 20% of the sample had macrocephaly and 1% microcephaly. There was no association between the presence of macrocephaly and subtype of ASD. The most associated comorbidity was attention-deficit/hyperactivity disorder (ADHD) 54.2%, followed by specific phobia 34%, dysthimia 29...
June 7, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28589965/generalization-of-extinguished-fear-to-untreated-fear-stimuli-after-exposure
#13
Friederike Preusser, Jürgen Margraf, Armin Zlomuzica
Exposure therapy is highly effective in treating excessive fear related to specific objects and/or situations. However, patients with anxiety disorders often display a generalization of fear responses towards conceptually and perceptually related stimuli and situations. It is unclear whether the beneficial effects of exposure on fear reduction towards treated fear stimuli can extend to untreated fear stimuli. Here, we investigated whether basic principles of extinction generalization apply to exposure. Spider-phobic participants were randomly assigned to either two sessions of exposure treatment (n=23) with spiders or no-treatment (n=24)...
June 7, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28580599/the-two-faces-of-avoidance-time-frequency-correlates-of-motivational-disposition-in-blood-phobia
#14
Rocco Mennella, Michela Sarlo, Simone Messerotti Benvenuti, Giulia Buodo, Giovanni Mento, Daniela Palomba
Contrary to other phobias, individuals with blood phobia do not show a clear-cut withdrawal disposition from the feared stimulus. The study of response inhibition provides insights into reduced action disposition in blood phobia. Twenty individuals with and 20 without blood phobia completed an emotional go/no-go task including phobia-related pictures, as well as phobia-unrelated unpleasant, neutral, and pleasant stimuli. Behavioral results did not indicate a phobia-specific reduced action disposition in the phobic group...
June 5, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28580504/emotion-focused-cognitive-behavioral-therapy-for-youth-with-anxiety-disorders-a-randomized-trial
#15
Cynthia Suveg, Anna Jones, Molly Davis, Marni L Jacob, Diana Morelen, Kristel Thomassin, Monica Whitehead
Difficulties with emotion regulation are a core feature of anxiety disorders (ADs) in children and adults. Interventions with a specific focus on emotion regulation are gaining empirical support. Yet, no studies to date have compared the relative efficacy of such interventions to existing evidence-based treatments. Such comparisons are necessary to determine whether emotion-focused treatments might be more effective for youth exhibiting broad emotion-regulation difficulties at pretreatment. This study examined an emotion-focused cognitive-behavioral therapy (ECBT) protocol in comparison to traditional cognitive-behavioral therapy (CBT) in a sample of children with a primary anxiety disorder diagnosis...
June 5, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28579966/problematic-alcohol-use-among-university-students
#16
Tesfa Mekonen, Wubalem Fekadu, Tefera Chane, Shimelash Bitew
BACKGROUND: Alcohol is attributable to many diseases and injury-related health conditions, and it is the fifth leading risk factor of premature death globally. Hence, the objective of this study was to assess the proportion and associated factors of problematic alcohol use among University students. MATERIAL AND METHODS: Cross-sectional study was conducted among 725 randomly selected University students from November to December 2015. Data were collected by self-administered questionnaire, and problematic alcohol use was assessed by Alcohol Use Disorder Identification Test...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28579072/the-impact-of-comorbid-post-traumatic-stress-disorder-in-patients-with-major-depressive-disorder-on-clinical-features-pharmacological-treatment-strategies-and-treatment-outcomes-results-from-a-cross-sectional-european-multicenter-study
#17
Markus Dold, Lucie Bartova, Alexander Kautzky, Daniel Souery, Julien Mendlewicz, Alessandro Serretti, Stefano Porcelli, Joseph Zohar, Stuart Montgomery, Siegfried Kasper
This international, multicenter, cross-sectional study comprising 1346 adult in- and outpatients with major depressive disorder (MDD) investigated the association between MDD as primary diagnosis and comorbid post-traumatic stress disorder (PTSD). In a cross-sectional data collection process, the presence of comorbid PTSD was determined by the Mini International Neuropsychiatric Interview (MINI) and the patients' socio-demographic, clinical, psychopharmacological, and response information were obtained. Clinical features between MDD with and without concurrent PTSD were compared using descriptive statistics, analyses of covariance (ANCOVA), and binary logistic regression analyses...
May 31, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28561634/-social-anxiety-and-self-esteem-hungarian-validation-of-the-brief-fear-of-negative-evaluation-scale-straightforward-items
#18
Dóra Perczel-Forintos, Szilvia Kresznerits
INTRODUCTION: Although social anxiety disorder (SAD) is the third most frequent emotional disorder with 13-15% prevalence rate, it remains unrecognized very often. Social phobia is associated with low self-esteem, high self-criticism and fear of negative evaluation by others. It shows high comorbidity with depression, alcoholism, drug addiction and eating disorders. AIM: To adapt the widely used "Fear of Negative Evaluation" (FNE) social phobia questionnaire. METHOD: Anxiety and mood disorder patients (n = 255) completed the Fear of Negative Evaluation Scale (30, 12 and 8 item-versions) as well as social cognition, anxiety and self-esteem questionnaires...
June 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28558881/social-anxiety-and-internet-socialization-in-indian-undergraduate-students-an-exploratory-study
#19
Bianca S Honnekeri, Akhil Goel, Maithili Umate, Nilesh Shah, Avinash De Sousa
BACKGROUND: Social Anxiety Disorder (SAD) is a globally prevalent, chronic, debilitating psychiatric disorder affecting youth. With comorbidities including major depression, substance abuse, lower educational and work attainment, and increased suicide risk, it has a significant public health burden. The objective of this study was to estimate the prevalence of SAD in urban Indian undergraduate students and to study their Facebook (FB) usage patterns. METHODS: In this exploratory cross-sectional study, 316 undergraduate students were screened for social anxiety using validated instruments, Social Interaction Anxiety Scale (SIAS) and Social Phobia Scale (SPS), and divided into two groups based on scores obtained...
June 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28558623/is-trypophobia-a-phobia
#20
Wang Can, Zhao Zhuoran, Jin Zheng
In the past 10 years, thousands of people have claimed to be affected by trypophobia, which is the fear of objects with small holes. Recent research suggests that people do not fear the holes; rather, images of clustered holes, which share basic visual characteristics with venomous organisms, lead to nonconscious fear. In the present study, both self-reported measures and the Preschool Single Category Implicit Association Test were adapted for use with preschoolers to investigate whether discomfort related to trypophobic stimuli was grounded in their visual features or based on a nonconsciously associated fear of venomous animals...
April 2017: Psychological Reports
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