keyword
MENU ▼
Read by QxMD icon Read
search

Toenail

keyword
https://www.readbyqxmd.com/read/28099608/subungual-squamous-cell-carcinoma
#1
Carolina Barbosa de Sousa Padilha, Laila Klotz de Almeida Balassiano, Julyana Calegari Pinto, Flávia Crespo Schueler de Souza, Bernard Kawa Kac, Curt Mafra Treu
Although subungual squamous cell carcinoma is rare, it is the most common primary malignant neoplasms in this location. The higher incidence occurs in the fingernails, but involvement of the toenails is also possible. Subungual squamous cell carcinoma often looks like other more common benign lesions, such as fungal infection, onychomycosis, or viral wart. These factors, together with a general lack of awareness of this disease among physicians, often result in delayed diagnosis. Therefore, it is underdiagnosed, with few reports in the literature...
November 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28056794/mercury-exposure-and-risk-of-cardiovascular-disease-a-nested-case-control-study-in-the-predimed-prevention-with-mediterranean-diet-study
#2
Mary K Downer, Miguel A Martínez-González, Alfredo Gea, Meir Stampfer, Julia Warnberg, Miguel Ruiz-Canela, Jordi Salas-Salvadó, Dolores Corella, Emilio Ros, Montse Fitó, Ramon Estruch, Fernando Arós, Miquel Fiol, José Lapetra, Lluís Serra-Majem, Monica Bullo, Jose V Sorli, Miguel A Muñoz, Antonio García-Rodriguez, Mario Gutierrez-Bedmar, Enrique Gómez-Gracia
BACKGROUND: Substantial evidence suggests that consuming 1-2 servings of fish per week, particularly oily fish (e.g., salmon, herring, sardines) is beneficial for cardiovascular health due to its high n-3 polyunsaturated fatty acid content. However, there is some concern that the mercury content in fish may increase cardiovascular disease risk, but this relationship remains unclear. METHODS: The PREDIMED trial included 7477 participants who were at high risk for cardiovascular disease at baseline...
January 5, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28040821/over-the-counter-and-natural-remedies-for-onychomycosis-do-they-really-work
#3
Pierre Halteh, Richard K Scher, Shari R Lipner
Onychomycosis is a fungal infection of the nail unit that may lead to dystrophy and disfigurement over time. It accounts for up to 50% of all nail conditions, with toenails affected more commonly than fingernails. Onychomycosis may affect quality of life and increase the prevalence and severity of foot ulcers in patients with diabetes. Available oral agents approved by the US Food and Drug Administration (FDA) for the treatment of onychomycosis include terbinafine and itraconazole, which have demonstrated good efficacy but are associated with the risk of systemic side effects and drug-drug interactions...
November 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28034734/preparation-and-evaluation-of-a-novel-dosage-form-for-onychomycosis
#4
Flavia Laffleur, Martin Ataii
Onychomycosis is a common infection of the nail caused by dermatophyte affecting mostly toenails in adults being associated with limited treatment options. In this study novel dosage forms were prepared and evaluated for their suitability in treatment of onychomycosis. Films were prepared comprising polymeric excipients such as chitosan, (hydroxypropyl)methyl cellulose, hydroxyethyl-cellulose, carboxymethylcellulose according to solvent evaporation method. Developed formulations were evaluated in terms of physical appearance, stability and adhesiveness...
December 26, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28025110/hypomethylation-of-inflammatory-genes-cox2-egr1-and-socs3-and-increased-urinary-8-nitroguanine-in-arsenic-exposed-newborns-and-children
#5
Preeyaphan Phookphan, Panida Navasumrit, Somchamai Waraprasit, Jeerawan Promvijit, Krittinee Chaisatra, Thitirat Ngaotepprutaram, Mathuros Ruchirawat
Early-life exposure to arsenic increases risk of developing a variety of non-malignant and malignant diseases. Arsenic-induced carcinogenesis may be mediated through epigenetic mechanisms and pathways leading to inflammation. Our previous study reported that prenatal arsenic exposure leads to increased mRNA expression of several genes related to inflammation, including COX2, EGR1, and SOCS3. This study aimed to investigate the effects of arsenic exposure on promoter DNA methylation and mRNA expression of these inflammatory genes (COX2, EGR1, and SOCS3), as well as the generation of 8-nitroguanine, which is a mutagenic DNA lesion involved in inflammation-related carcinogenesis...
December 23, 2016: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28004227/trichophyton-rubrum-infection-characterized-by-majocchi-s-granuloma-and-deeper-dermatophytosis-case-report-and-review-of-published-literature
#6
Huilin Su, Li Li, Benlin Cheng, Junhao Zhu, Qiangqiang Zhang, Jinhua Xu, Min Zhu
Infections caused by Trichophyton rubrum are very common in dermatological disease. It most often appears as superficial cutaneous mycosis, such as tinea manuum, tinea pedis, and tinea corporis. However, deep infection caused by T. rubrum was rarely reported. We describe a case of mixed type of deep infection caused by T. rubrum in a 45-year-old man with no significant immunodeficiency. This patient had a history of onychomycosis on the toenails without regular treatment for nearly 6 years. And, he had erythema, papule, and nodules on the submandibular area, neck, and chest for almost 1 year...
December 21, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27976363/acute-skin-and-hair-symptoms-followed-by-severe-delayed-eye-complications-in-subjects-using-the-synthetic-opioid-mt-45
#7
A Helander, M Bradley, A Hasselblad, L Norlén, I Vassilaki, M Bäckberg, J Lapins
BACKGROUND: The introduction of unclassified new psychoactive substances (NPS) on the recreational drugs market through open online sale ('legal highs' or 'Internet drugs') continues unabated and represents a growing health hazard. The use of NPS has resulted in numerous, severe, adverse events and fatalities, due to unintended overdose or unknown toxic side-effects. OBJECTIVES: To try to find a possible common underlying cause for the skin-hair-eye symptoms complex observed in three men...
December 14, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27966667/arsenic-levels-in-cutaneous-appendicular-organs-are-correlated-with-digitally-evaluated-hyperpigmented-skin-of-the-forehead-but-not-the-sole-in-bangladesh-residents
#8
Ichiro Yajima, Nazmul Ahsan, Anwarul Azim Akhand, Mm Aeorangajeb Al Hossain, Masafumi Yoshinaga, Nobutaka Ohgami, Machiko Iida, Reina Oshino, Mariko Naito, Kenji Wakai, Masashi Kato
There has been no report showing the effect of arsenic level on digitized skin pigmentation level, a typical diagnostic marker for arsenicosis. Correlations among history of drinking well water, arsenic levels in hair and toenails, and digitalized skin pigmentation levels (L*-value) in sunlight-exposed (forehead) and unexposed (sole) skin areas digitally evaluated by using a reflectance spectrophotometer were examined in 150 residents of Bangladesh. Univariate analysis showed that arsenic levels in hair and toenails of subjects with a history of drinking well water were 10...
December 14, 2016: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/27966664/maternal-fetal-metabolomes-appear-to-mediate-the-impact-of-arsenic-exposure-on-birth-weight-a-pilot-study
#9
Yongyue Wei, Qianwen Shi, Zhaoxi Wang, Ruyang Zhang, Li Su, Quazi Quamruzzaman, Mahmuder Rahman, Feng Chen, David C Christiani
Arsenic exposure has been associated with low birth weight. However, the underlying mechanisms are not well understood. Alterations to metabolites may act as causal mediators of the effect of arsenic exposure on low birth weight. This pilot study aimed to explore the role of metabolites in mediating the association of arsenic exposure on infant birth weight. Study samples were selected from a well-established prospectively enrolled cohort in Bangladesh comprising 35 newborns and a subset of 20 matched mothers...
December 14, 2016: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/27938809/acral-manifestations-of-fungal-infections
#10
Zekayi Kutlubay, Gürkan Yardımcı, A Serda Kantarcıoğlu, Server Serdaroğlu
Fungal infections, which are named according to the body site involved, can affect any skin area, the fingernails, or the toenails. Numerous fungal agents are responsible for both superficial and deep fungal diseases. Dermatophytes and Candida spp are the most common causative organisms on the surface of the hands, feet, and nails of patients with superficial fungal diseases; however, although deep fungal infections of the skin are less common compared with superficial fungal diseases, their incidence is increasing worldwide due to cross-border travel...
January 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/27908422/toenail-mercury-and-dyslipidemia-interaction-with-selenium
#11
Kyong Park, Eunmin Seo
BACKGROUND: Although compelling evidences from in vivo and in vitro studies exist, limited studies have examined the association between chronic mercury exposure and dyslipidemia. Particularly, data are sparse regarding the influence of selenium on this association of mercury with dyslipidemia in humans. PURPOSE: The purpose of the current study was to examine the associations of toenail mercury with dyslipidemia and its components, and to examine whether selenium in toenails modifies these associations...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27906614/development-of-new-forms-of-self-injurious-behavior-following-total-dental-extraction-in-lesch-nyhan-disease
#12
Livia Gisbert de la Cuadra, Rosa J Torres, Luis M Beltrán, Arantxa Sánchez, Juan G Puig
We report two Lesch-Nyhan Disease (LND) patients who developed new forms of self-injurious behavior following total dental extraction. Patients 1 and 2 were submitted to total teeth extraction at the age of 13 and 8 years, respectively, due to continuous self-biting, not prevented by mouth guards. Severity of dystonia was markedly reduced and quality of life improved. After 12 and 17 months, respectively, patient 1 started rubbing one foot against other and scratching toenails with his hands, and patient 2 stuck his legs and feet against hard objects...
December 2016: Nucleosides, Nucleotides & Nucleic Acids
https://www.readbyqxmd.com/read/27876085/onychomycosis-in-diabetic-patients-in-fako-division-of-cameroon-prevalence-causative-agents-associated-factors-and-antifungal-sensitivity-patterns
#13
Marvlyn Eba, Anna Longdoh Njunda, Rene Njikam Mouliom, Emmanuel Tebit Kwenti, Anold Nsoh Fuh, Gordon Takop Nchanji, Julius Atashili
BACKGROUND: Onychomycosis is an infection of the nail unit by a fungus. This is a very common infection amongst diabetics. Its occurrence among diabetics in Fako division is unknown. In this study we provide information on the characteristics of onychomycosis in diabetics in Fako division, Cameroon. METHODS: A cross-sectional descriptive and analytical hospital-based study was conducted in two diabetic clinics in the Buea and Limbe regional hospitals. We recruited 152 consenting diabetics into the study...
November 22, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27873356/nail-psoriasis-a-systematic-evaluation-in-313-children-with-psoriasis
#14
Diane Pourchot, Christine Bodemer, Alice Phan, Anne-Claire Bursztejn, Smaïl Hadj-Rabia, Franck Boralevi, Juliette Miquel, Thomas Hubiche, Eve Puzenat, Anne-Laure Souillet, Ingrid Kupfer, Maryam Piram, Alain Beauchet, Emmanuel Mahé
BACKGROUND/OBJECTIVES: Little information is available on the prevalence and clinical aspects of nail involvement in children with psoriasis. The objective of this study was to evaluate the prevalence and clinical aspects of and the risk factors for nail involvement in French children with psoriasis. METHODS: We performed a multicenter, cross-sectional study in 23 French dermatology centers. All children seen during the 1-year study were systematically included...
November 22, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27856773/real-world-efficacy-of-1064-nm-nd-yag-laser-for-the-treatment-of-onychomycosis
#15
REVIEW
Jason K Rivers, Brianne J Vestvik, Jonathan Berkowitz
BACKGROUND: Onychomycosis is a cosmetic and, at times, medical concern; therefore, effective and safe alternatives to treatment are needed. OBJECTIVE: To determine the efficacy of a 1064-nm Nd:YAG laser for the treatment of onychomycosis in a real-world setting. METHODS: A single-centre retrospective chart review was conducted between 2012 and 2013. One hundred consecutive patients with a culture- and/or potassium hydroxide-confirmed diagnosis of onychomycosis were treated at least twice...
November 16, 2016: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27852988/clinical-characteristics-of-acquired-ungual-fibrokeratoma
#16
Sewon Hwang, Miri Kim, Baik Kee Cho, Hyun Jeong Park
BACKGROUND: Acquired ungual fibrokeratomas are uncommon fibrous tissue tumors located in the ungual area. Though there are many reports of this entity, only some reports have reviewed the clinical features of the tumor. AIMS: The aim of this study was to clarify the clinical characteristics of acquired ungual fibrokeratomas. METHODS: We reviewed twenty patients who were treated surgically at our clinic from 2003 to 2014 for acquired ungual fibrokeratomas confirmed on histopathological examination...
November 11, 2016: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/27843933/onychomycosis-practical-approaches-to-minimize-relapse-and-recurrence
#17
REVIEW
Antonella Tosti, Boni E Elewski
INTRODUCTION: Toenail onychomycosis is a common disease in which treatment options are limited and treatment failures and disease recurrence are frequently encountered. It usually requires many months of treatment, and recurrence may occur in more than half of the patients within 1 year or more after the infection has been eradicated. Data on long-term treatment, follow-up and recurrence are limited. OBJECTIVE: Our objective is to interpret these data and recommend practical approaches that should minimize recurrence based on our clinical experience...
September 2016: Skin Appendage Disorders
https://www.readbyqxmd.com/read/27826474/analysis-of-the-survival-of-arterialized-venous-toenail-flap-with-reference-to-changes-in-blood-circulation-during-the-postoperative-period-in-2-patients
#18
Naohiro Ishii, Yusuke Shimizu, Marie Aoki, Ayaka Suzuki, Kazuo Kishi
Various techniques for nail reconstruction have been reported until now; however, a simple one providing good esthetic results was difficult to find. Arterialized venous toenail flap is a free flap that includes the nail bed and matrix with a pedicle formed solely by the subcutaneous vein of the toe. The use of this flap is minimally invasive and easy, and the flap has a high survival rate. The mechanism of graft survival remains unknown given the nonphysiologic circulation. To the best of our knowledge, no studies have explained this mechanism with reference to detailed postoperative course...
October 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27825389/maternal-arsenic-exposure-and-gestational-diabetes-and-glucose-intolerance-in-the-new-hampshire-birth-cohort-study
#19
Shohreh F Farzan, Anala Gossai, Yu Chen, Lisa Chasan-Taber, Emily Baker, Margaret Karagas
BACKGROUND: Gestational diabetes mellitus (GDM) is a major pregnancy complication with detrimental effects for both mothers and their children. Accumulating evidence has suggested a potential role for arsenic (As) exposure in the development of GDM, but current studies have not assessed As exposure from water, urine or toenail samples. METHODS: We investigated the association between As exposure and risk of glucose intolerance and GDM among 1151 women enrolled in the New Hampshire Birth Cohort Study...
November 8, 2016: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/27825175/update-on-efinaconazole-10-topical-solution-for-the-treatment-of-onychomycosis
#20
A K Gupta, C Studholme
Efinaconazole 10% nail solution is a novel topical antifungal drug for the treatment of onychomycosis. Two Phase III trials were completed using efinaconazole 10% nail solution, where 17.8% and 15.2% of patients achieved complete cure, and 55.2% and 53.4% achieved mycological cure. Several post hoc analyses were carried out using data from Phase III trials to determine the efficacy of efinaconazole with respect to disease duration, disease progression, and comorbidities of diabetes or tinea pedis with onychomycosis...
November 2016: Skin Therapy Letter
keyword
keyword
17323
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"