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https://www.readbyqxmd.com/read/29031217/quality-of-life-and-burden-in-caregivers-of-youth-with-obsessive-compulsive-disorder-presenting-for-intensive-treatment
#1
Monica S Wu, Rebecca Hamblin, Joshua Nadeau, Jessica Simmons, Ashley Smith, Meredith Wilson, Stephanie Eken, Brent Small, Vicky Phares, Eric A Storch
BACKGROUND: Pediatric obsessive-compulsive disorder (OCD) is associated with deleterious familial effects; caregivers are often enmeshed in the disorder and can experience considerable burden and decreased quality of life (QoL). Consequently, this study examined burden and QoL in caregivers of youth with OCD enrolled in an intensive outpatient or partial hospitalization program. METHOD: The relationships between caregiver QoL and burden and the following variables were investigated: OCD symptom severity, functioning (youth functional impairment, general family functioning), family (family accommodation, parental relationship satisfaction, positive aspects of caregiving), and comorbid psychopathology (caregiver anxiety and depressive symptoms, youth internalizing and externalizing behaviors)...
August 30, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29027607/developing-a-patient-reported-outcome-measure-for-hiv-care-on-perceived-barriers-to-antiretroviral-adherence-assessing-the-needs-of-hiv-clinicians-through-qualitative-analysis
#2
Isabelle Toupin, Kim Engler, David Lessard, Leo Wong, Andràs Lènàrt, Bruno Spire, François Raffi, Bertrand Lebouché
PURPOSE: To identify HIV clinicians' needs for the clinical use of a new patient-reported outcome measure (PRO) on barriers to antiretroviral therapy (ART) adherence. METHODS: In 2015, five focus groups with 31 clinicians from France were transcribed, coded with Atlas.ti, and submitted to a typological analysis. RESULTS: The analysis identified seven patient profiles, each tied to distinct barriers to adherence and to specific needs for the PRO's content, data collection and transmission...
October 13, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/29026257/fronto-striatal-glutamate-in-autism-spectrum-disorder-and-obsessive-compulsive-disorder
#3
Jilly Naaijen, Marcel P Zwiers, Houshang Amiri, Steven Cr Williams, Sarah Durston, Bob Oranje, Daniel Brandeis, Regina Boecker-Schlier, Matthias Ruf, Isabella Wolf, Tobias Banaschewski, Jeffrey C Glennon, Barbara Franke, Jan K Buitelaar, David J Lythgoe
This corrects the article DOI: 10.1038/npp.2016.260.
November 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29024649/obsessing-about-uncertainty
#4
Jacqueline Scholl, Matthew F S Rushworth
A striking observation in obsessive-compulsive disorder is that patients know that their obsessions and compulsions are excessive, but their symptoms nevertheless persist. Drawing on computational models from basic neuroscience, Vaghi and colleagues (2017) suggest a quantitative account of this clinical finding.
October 11, 2017: Neuron
https://www.readbyqxmd.com/read/29024130/continuity-between-dsm-5-section-ii-and-section-iii-personality-traits-for-obsessive-compulsive-personality-disorder
#5
Jacqueline Liggett, Martin Sellbom, Bo Bach
OBJECTIVE: Obsessive-compulsive personality disorder (OCPD) is formally operationalized in Section II of the DSM-5 by a heterogeneous collection of 8 categorical criteria. Section III contains an alternative model operationalizing personality disorders via dimensional personality traits and associated impairment. The extent to which the personality traits used to define OCPD in Section III correspond with the Section II operationalization of the disorder is contested. The current study aims to contribute to the evidence base necessary to solidify the optimal trait profile for this disorder via a more fine-tuned examination of OCPD...
October 11, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/29021824/intense-obsessional-interests-in-children-with-gender-dysphoria-a-cross-validation-study-using-the-teacher-s-report-form
#6
Kenneth J Zucker, A Natisha Nabbijohn, Alanna Santarossa, Hayley Wood, Susan J Bradley, Joanna Matthews, Doug P VanderLaan
OBJECTIVE: This study assessed whether children clinically referred for gender dysphoria (GD) show symptoms that overlap with Autism Spectrum Disorder (ASD). Circumscribed preoccupations/intense interests and repetitive behaviors were considered as overlapping symptoms expressed in both GD and ASD. METHODS: To assess these constructs, we examined Items 9 and 66 on the Teacher's Report Form (TRF), which measure obsessions and compulsions, respectively. RESULTS: For Item 9, gender-referred children (n = 386) were significantly elevated compared to the referred (n = 965) and non-referred children (n = 965) from the TRF standardization sample...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/29020038/correction-integrating-genetic-neuropsychological-and-neuroimaging-data-to-model-early-onset-obsessive-compulsive-disorder-severity
#7
Sergi Mas, Patricia Gassó, Astrid Morer, Anna Calvo, Nuria Bargalló, Amalia Lafuente, Luisa Lázaro
[This corrects the article DOI: 10.1371/journal.pone.0153846.].
2017: PloS One
https://www.readbyqxmd.com/read/29019520/feelings-and-perceptions-of-women-recovering-from-anorexia-nervosa-regarding-their-eating-behavior
#8
Nathalia Petry, Francisco de Assis Guedes de Vasconcelos, Larissa da Cunha Feio Costa
According to the phenomenological approach, observing a phenomenon through the perspective of those who lived it may be necessary to acquire fully comprehension of it. Therefore, to fully understand the eating behavior during anorexia nervosa and during its recovery, this study investigated individual perceptions and feelings of three women recovering from anorexia nervosa. This study is characterized as a qualitative research with phenomenological approach. The data were collected through interviews and analyzed following steps proposed by phenomenology researchers...
October 9, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29018554/psychiatric-neurosurgery-in-the-21st-century-overview-and-the-growth-of-deep-brain-stimulation
#9
REVIEW
Kenneth Barrett
Ambulatory deep brain stimulation (DBS) became possible in the late 1980s and was initially used to treat people with movement disorders. Trials of DBS in people with treatment-resistant psychiatric disorder began in the late 1990s, initially focusing on obsessive-compulsive disorder, major depressive disorder and Tourette syndrome. Despite methodological issues, including small participant numbers and lack of consensus over brain targets, DBS is now being trialled in a wide range of psychiatric conditions...
October 2017: BJPsych Bulletin
https://www.readbyqxmd.com/read/29017175/body-weight-changes-after-deep-brain-stimulation-for-obsessive-compulsive-disorder-or-depression
#10
Rosalie S N Linssen, Marloes S Oudijn, Mariska Mantione, Pepijn van den Munckhof, Damiaan Denys, P Richard Schuurman
BACKGROUND: In 2010, we published an often-cited case report describing smoking cessation and substantial weight loss after deep brain stimulation (DBS) for obsessive-compulsive disorder (OCD) in an obese patient. To test whether this single observation was also observed in the treated population at large, the weight changes of a larger cohort of patients who underwent DBS for OCD or major depressive disorder (MDD) were studied. RESULTS: Data were available for 46 patients (30 OCD and 16 MDD patients; mean age 46...
October 11, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28992712/-biologic-aspects-of-adhd-and-conduct-disorders-in-childhood-and-adolescence-selected-preventive-aspects
#11
Ivo Paclt, Nikol Přibilová
Next to environmental factors and problems with interpersonal interaction in family represent developmental findings the basic of understanding these disorders (ADHD, conduct disorders, obsessive-compulsive disorders, tic disorders etc.). Knowledges of neurodevelopment disorders represent new possibilities of prevention and treatment.
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/28992533/neural-correlates-of-affective-and-non-affective-cognition-in-obsessive-compulsive-disorder-a-meta-analysis-of-functional-imaging-studies
#12
A Rasgon, W H Lee, E Leibu, A Laird, D Glahn, W Goodman, S Frangou
Obsessive compulsive disorder (OCD) is characterized by intrusive thoughts and repetitive ritualistic behaviors and has been associated with diverse functional brain abnormalities. We sought to synthesize current evidence from functional magnetic resonance imaging (fMRI) studies and examine their alignment to pathogenetic models of OCD. Following systematic review, we identified 54 task-fMRI studies published in the last decade comparing adults with OCD (n=1186) to healthy adults (n=1159) using tasks of affective and non-affective cognition...
September 1, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28990850/the-relationship-between-toxoplasma-gondii-igg-antibodies-and-generalized-anxiety-disorder-and-obsessive-compulsive-disorder-in-children-and-adolescents-a-new-approach
#13
İsmail Akaltun, Soner Sertan Kara, Tayfun Kara
AIM: Toxoplasma gondii may play a role in the development of psychiatric diseases by affecting the brain. The purpose of this study was to examine the relation between serum toxoplasma IgG positivity and obsessive-compulsive disorder (OCD) and generalized anxiety disorder (GAD) in children and adolescents. METHOD: Sixty patients diagnosed with OCD and 60 patients with GAD presenting to the pediatric psychiatry clinic, together with 60 control group subjects with no psychiatric diagnosis, were included in the study...
October 9, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28990738/treatment-of-obsessive-morbid-jealousy-with-cognitive-analytic-therapy-an-adjudicated-hermeneutic-single-case-efficacy-design-evaluation
#14
Louise Curling, Stephen Kellett, Peter Totterdell, Glenys Parry, Gillian Hardy, Katherine Berry
OBJECTIVE: The evidence base for the treatment of morbid jealousy with integrative therapies is thin. This study explored the efficacy of cognitive analytic therapy (CAT). DESIGN: An adjudicated hermeneutic single-case efficacy design evaluated the cognitive analytic treatment of a patient meeting diagnostic criteria for obsessive morbid jealousy. METHOD: A rich case record was developed using a matrix of nomothetic and ideographic quantitative and qualitative outcomes...
October 9, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28988149/neural-dysfunction-during-temporal-discounting-in-paediatric-attention-deficit-hyperactivity-disorder-and-obsessive-compulsive-disorder
#15
Luke J Norman, Christina O Carlisi, Anastasia Christakou, Kaylita Chantiluke, Clodagh Murphy, Andrew Simmons, Vincent Giampietro, Michael Brammer, David Mataix-Cols, Katya Rubia
Both Attention-Deficit/Hyperactivity Disorder (ADHD) and Obsessive-Compulsive Disorder (OCD) are associated with choice impulsivity, i.e. the tendency to prefer smaller immediate rewards over larger delayed rewards. However, the extent to which this impulsivity is mediated by shared or distinct underlying neural mechanisms is unclear. Twenty-six boys with ADHD, 20 boys with OCD and 20 matched controls (aged 12-18) completed an fMRI version of an individually adjusted temporal discounting (TD) task which requires choosing between a variable amount of money now or £100 in one week, one month or one year...
November 30, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28984854/adult-zebrafish-in-cns-disease-modeling-a-tank-that-s-half-full-not-half-empty-and-still-filling
#16
Darya A Meshalkina, Elana V Kysil, Jason E Warnick, Konstantin A Demin, Allan V Kalueff
The zebrafish (Danio rerio) is increasingly used in a broad array of biomedical studies, from cancer research to drug screening. Zebrafish also represent an emerging model organism for studying complex brain diseases. The number of zebrafish neuroscience studies is exponentially growing, significantly outpacing those conducted with rodents or other model organisms. Yet, there is still a substantial amount of resistance in adopting zebrafish as a first-choice model system. Studies of the repertoire of zebrafish neural and behavioral functions continue to reveal new opportunities for understanding the pathobiology of various CNS deficits...
October 6, 2017: Lab Animal
https://www.readbyqxmd.com/read/28982038/drop-out-and-efficacy-of-group-versus-individual-cognitive-behavioural-therapy-what-works-best-for-obsessive-compulsive-disorder-a-systematic-review-and-meta-analysis-of-direct-comparisons
#17
REVIEW
Andrea Pozza, Davide Dèttore
Cognitive behavioural therapy (CBT) is the first-line psychological treatment for Obsessive-Compulsive Disorder (OCD). However, a relevant proportion of individuals with OCD remain untreated or inadequately treated. Group cognitive behavioural therapy (GCBT) may be an alternative treatment modality. Little knowledge is available about the efficacy between GCBT versus individual CBT, particularly on long-term secondary outcomes including anxiety and depression. In addition, drop-out rates have not been investigated by previous meta-analyses...
September 25, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28979736/elderly-peoples-experiences-of-nursing-homes-in-bam-city-a-qualitative-study
#18
Neda Mohammadinia, Mohammad Ali Rezaei, Foroozan Atashzadeh-Shoorideh
BACKGROUND: With the increasing number of elderly, especially in recent decades, transfer to nursing homes and the number of centers has also increased but experiences and problems of elders in these centers is less considered. So, the goal of this study is to explore the Elderly peoples' experiences of nursing homes. METHODS: The current research was performed using a phenomenological approach in 2016. Participation in the study is comprised of the elderly residents in a nursing home in Bam city who were selected based on an objective-oriented approach...
August 2017: Electronic Physician
https://www.readbyqxmd.com/read/28976410/early-onset-schizophrenia-associated-with-obsessive-compulsive-disorder-clinical-features-and-correlates
#19
Burak Baytunca, Tuğba Kalyoncu, Ismail Ozel, Serpil Erermiş, Bülent Kayahan, Dost Öngur
OBJECTIVES: Obsessive-compulsive disorder (OCD) is notably a comorbid disorder in patients with schizophrenia. This study aimed to evaluate clinical features and correlates of early onset patients with schizophrenia with OCD. METHODS: In the present study, we included 10 patients with both schizophrenia and OCD and 19 patients with schizophrenia without OCD. The mean antipsychotic doses the patients needed for treatment are standardized as chlorpromazine equivalent dose...
October 2, 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28972381/distinguishing-subjective-halitosis
#20
Murat Aydin, Mustafa Çağrı Derici, Defne Yalçın Yeler, Murat Özen Eren
Halitosis is chronic, endogenous malodor that is etiologically classified. Subjective halitosis, which may appear in clinically neurologic (neurogenic) or psychologic (psychogenic) forms, cannot be confirmed by using tests or performing visual inspection despite insistent complaints of malodor by the patient. Neurogenic forms mainly consist of chemosensory dysfunctions (dysguisa, dysosmia) and self-halitosis (retronasal olfaction, bloodborne olfactory receptor responses, phantosmia); whereas psychogenic forms are olfactory hallucinations, halitophobia, olfactory obsession, and delusional halitosis...
October 2017: Compendium of Continuing Education in Dentistry
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