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Image fusion radiation therapy

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https://www.readbyqxmd.com/read/28048721/su-f-j-222-using-pet-imaging-to-evaluate-proliferation-and-blood-flow-in-irradiated-and-non-irradiated-bone-marrow-1-year-after-chemoradiation-therapy
#1
S McGuire, L Ponto, Y Menda
PURPOSE: To compare proliferation and blood flow in pelvic and thoracic bone marrow 1 year after pelvic chemoradiation. METHODS: Sixteen pelvic cancer patients were enrolled in an IRB-approved protocol to acquire FLT PET images during radiation therapy simulation (baseline) and 1 year after chemoradiation therapy. Three subjects also had optional O-15 water PET images acquired 1 year after chemoradiation therapy. Baseline FLT PET images were used to create IMRT plans to spare pelvic bone marrow identified as regions with FLT SUV ≥ 2 without compromising PTV coverage or OAR sparing...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048133/su-f-j-113-multi-atlas-based-automatic-organ-segmentation-for-lung-radiotherapy-planning
#2
J Kim, J Han, S Ailawadi, J Baker, A Hsia, Z Xu, S Ryu
PURPOSE: Normal organ segmentation is one time-consuming and labor-intensive step for lung radiotherapy treatment planning. The aim of this study is to evaluate the performance of a multi-atlas based segmentation approach for automatic organs at risk (OAR) delineation. METHODS: Fifteen Lung stereotactic body radiation therapy patients were randomly selected. Planning CT images and OAR contours of the heart - HT, aorta - AO, vena cava - VC, pulmonary trunk - PT, and esophagus - ES were exported and used as reference and atlas sets...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047834/su-c-bra-04-automated-segmentation-of-head-and-neck-ct-images-for-radiotherapy-treatment-planning-via-multi-atlas-machine-learning-maml
#3
X Ren, G Sharp, H Gao
PURPOSE: Accurate image segmentation is a crucial step during image guided radiation therapy. This work proposes multi-atlas machine learning (MAML) algorithm for automated segmentation of head-and-neck CT images. METHODS: As the first step, the algorithm utilizes normalized mutual information as similarity metric, affine registration combined with multiresolution B-Spline registration, and then fuses together using the label fusion strategy via Plastimatch. As the second step, the following feature selection strategy is proposed to extract five feature components from reference or atlas images: intensity (I), distance map (D), box (B), center of gravity (C) and stable point (S)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047471/su-f-p-23-setup-uncertainties-for-the-lung-stereotactic-body-radiation-therapy
#4
Q Zhang, Y Cao, A Jamshidi, P Vigneri, C Madu, L Potters, E Klein
PURPOSE: The Exactrack X-ray system with six degree-of-freedom (6DoF) adjustment ability can be used for setup of lung stereotactic body radiation therapy. The setup uncertainties from ExacTrack 6D system were analyzed. METHODS: The Exactrack X-ray 6D image guided radiotherapy system is used in our clinic. The system is an integration of 2 subsystems: (1): an infrared based optical position system and (2) a radiography kV x-ray imaging system. The infrared system monitors reflective body markers on the patient's skin to assistant in the initial setup...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046310/th-cd-206-02-best-in-physics-imaging-3d-prostate-segmentation-in-mr-images-using-patch-based-anatomical-signature
#5
X Yang, A Jani, P Rossi, H Mao, W Curran, T Liu
PURPOSE: MRI has shown promise in identifying prostate tumors with high sensitivity and specificity for the detection of prostate cancer. Accurate segmentation of the prostate plays a key role various tasks: to accurately localize prostate boundaries for biopsy needle placement and radiotherapy, to initialize multi-modal registration algorithms or to obtain the region of interest for computer-aided detection of prostate cancer. However, manual segmentation during biopsy or radiation therapy can be time consuming and subject to inter- and intra-observer variation...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27987612/magnetic-resonance-venography-and-three-dimensional-image-fusion-guidance-provide-a-novel-paradigm-for-endovascular-recanalization-of-chronic-central-venous-occlusion
#6
Adeline Schwein, Tony Lu, Ponraj Chinnadurai, Danai Kitkungvan, Dipan J Shah, Nabil Chakfe, Alan B Lumsden, Jean Bismuth
OBJECTIVE: Endovascular recanalization is considered first-line therapy for chronic central venous occlusion (CVO). Unlike arteries, in which landmarks such as wall calcifications provide indirect guidance for endovascular navigation, sclerotic veins without known vascular branching patterns impose significant challenges. Therefore, safe wire access through such chronic lesions mostly relies on intuition and experience. Studies have shown that magnetic resonance venography (MRV) can be performed safely in these patients, and the boundaries of occluded veins may be visualized on specific MRV sequences...
January 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27966187/three-dimensional-image-fusion-guidance-of-percutaneous-pulmonary-valve-implantation-to-reduce-radiation-exposure-and-contrast-dose-a%C3%A2-comparison-with-traditional-two-dimensional-and-three-dimensional-rotational-angiographic-guidance
#7
S Goreczny, T Moszura, P Dryzek, M Lukaszewski, A Krawczuk, J Moll, G J Morgan
INTRODUCTION: Three-dimensional rotational angiography (3DRA) has been used in the guidance of various transcatheter therapies including percutaneous pulmonary valve implantation (PPVI). The most recently available 3D image fusion software (VesselNavigator, Philips) extends this technology to use pre-registered computed tomography or magnetic resonance imaging datasets, promising reductions in contrast and radiation exposure along with shorter procedural times. METHODS: In this retrospective review, patients were assigned to three groups according to the mode of imaging guidance: two-dimensional angiography (2DA), 3DRA and VesselNavigator (VN) assisted valve implantation...
December 13, 2016: Netherlands Heart Journal
https://www.readbyqxmd.com/read/27847573/the-effect-of-perioperative-radiation-therapy-on-spinal-bone-fusion-following-spine-tumor-surgery
#8
Tae-Kyum Kim, Wonik Cho, Sang Min Youn, Ung-Kyu Chang
INTRODUCTION: Perioperative irradiation is often combined with spine tumor surgery. Radiation is known to be detrimental to healing process of bone fusion. We tried to investigate bone fusion rate in spine tumor surgery cases with perioperative radiation therapy (RT) and to analyze significant factors affecting successful bone fusion. METHODS: Study cohort was 33 patients who underwent spinal tumor resection and bone graft surgery combined with perioperative RT...
November 2016: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/27582607/mri-guided-prostate-biopsy-of-native-and-recurrent-prostate-cancer
#9
REVIEW
David A Woodrum, Krzysztof R Gorny, Bernadette Greenwood, Lance A Mynderse
Prostate cancer is the most commonly diagnosed noncutaneous cancer and second-leading cause of death in men. Many patients with clinically organ-confined prostate cancer undergo definitive, curative treatment of the whole gland with either radical prostatectomy or radiation therapy. However, many men are reluctant to take the definitive step due to potential morbidity associated with either therapy. A growing interest in active surveillance or focal therapy has emerged as realistic alternatives for many patients...
September 2016: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/27561802/-crizotinib-treatment-combined-with-resection-and-whole-brain-radiation-therapy-%C3%A2-in-a-ros1-rearranged-lung-adenocarcinoma-with-brain-metastasis-%C3%A2-case-report-and-literature-review
#10
Min Zhang, Ligong Nie, Jiayong Zhang
BACKGROUND: Lung cancer with brain metastasis had poor prognosis. Crizotinib had been confirmed to be used in ROS1 (C-ros oncogene 1 receptor tyrosine kinase) rearranged lung adenocarcinoma, but its efficacy in lung cancer with brain metastasis was poor due to the blood brain barrier. In the present study, we reported one case of ROS1 fusion lung adenocarcinoma with symptomatic brain matastasis, who was treated with brain metastases resection, crizotinib, and whole brain radiotherapy plus boost to residual brain metastasis...
August 20, 2016: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/27524504/atlas-guided-generation-of-pseudo-ct-images-for-mri-only-and-hybrid-pet-mri-guided-radiotherapy-treatment-planning
#11
Hossein Arabi, Nikolaos Koutsouvelis, Michel Rouzaud, Raymond Miralbell, Habib Zaidi
Magnetic resonance imaging (MRI)-guided attenuation correction (AC) of positron emission tomography (PET) data and/or radiation therapy (RT) treatment planning is challenged by the lack of a direct link between MRI voxel intensities and electron density. Therefore, even if this is not a trivial task, a pseudo-computed tomography (CT) image must be predicted from MRI alone. In this work, we propose a two-step (segmentation and fusion) atlas-based algorithm focusing on bone tissue identification to create a pseudo-CT image from conventional MRI sequences and evaluate its performance against the conventional MRI segmentation technique and a recently proposed multi-atlas approach...
September 7, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27512571/practice-patterns-of-radiation-therapy-technology-in-australia-results-of-a-national-audit
#12
Pete Bridge, Shane Dempsey, Eileen Giles, Sharon Maresse, Giulia McCorkell, Craig Opie, Caroline Wright, Mary-Ann Carmichael
INTRODUCTION: This article presents the results of a single-day census of radiation therapy (RT) treatment and technology use in Australia. The primary aim of the study was to ascertain patterns of RT practice and technology in use across Australia. These data were primarily collated to inform curriculum development of academic programs, thereby ensuring that training is matched to workforce patterns of practice. METHODS: The study design was a census method with all 59 RT centres in Australia being invited to provide quantitative summary data relating to patient case mix and technology use on a randomly selected but common date...
December 2015: Journal of Medical Radiation Sciences
https://www.readbyqxmd.com/read/27504134/single-fraction-multimodal-image-guided-focal-salvage-high-dose-rate-brachytherapy-for-recurrent-prostate-cancer
#13
Constantinos Zamboglou, Hans-Christian Rischke, Philipp Tobias Meyer, Sven Knobe, Natalja Volgeova-Neher, Michael Kollefrath, Cordula Annette Jilg, Anca Ligia Grosu, Dimos Baltas, Malte Kroenig
PURPOSE: We present a novel method for treatment of locally recurrent prostate cancer (PCa) following radiation therapy: focal, multimodal image guided high-dose-rate (HDR) brachytherapy. MATERIAL AND METHODS: We treated two patients with recurrent PCa after primary (#1) or adjuvant (#2) external beam radiation therapy. Multiparametric magnetic resonance imaging (mpMRI), choline, positron emission tomography combined with computed tomography (PET/CT), or prostate-specific membrane antigen (PSMA)-PET combined with CT identified a single intraprostatic lesion...
June 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/27277039/minimizing-treatment-planning-errors-in-proton-therapy-using-failure-mode-and-effects-analysis
#14
Yuanshui Zheng, Randall Johnson, Gary Larson
PURPOSE: Failure mode and effects analysis (FMEA) is a widely used tool to evaluate safety or reliability in conventional photon radiation therapy. However, reports about FMEA application in proton therapy are scarce. The purpose of this study is to apply FMEA in safety improvement of proton treatment planning at their center. METHODS: The authors performed an FMEA analysis of their proton therapy treatment planning process using uniform scanning proton beams. The authors identified possible failure modes in various planning processes, including image fusion, contouring, beam arrangement, dose calculation, plan export, documents, billing, and so on...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27260562/single-fraction-spine-stereotactic-body-radiation-therapy-for-the-treatment-of-chordoma
#15
Edward W Jung, David L Jung, Ehsan H Balagamwala, Lilyana Angelov, John H Suh, Toufik Djemil, Anthony Magnelli, Samuel T Chao
PURPOSE: Chordoma is a radioresistant tumor that presents a therapeutic challenge with spine involvement, as high doses of radiation are needed for local control while limiting dose to the spinal cord. The purpose of this study is to determine the efficacy and safety of single-fraction spine stereotactic body radiation therapy for the treatment of spine chordoma. METHODS: A retrospective review of our institutional database from 2006 to 2013 identified 8 patients (12 cases) with chordoma of the spine who were treated with spine stereotactic body radiation therapy...
June 3, 2016: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/27257417/survey-on-gynecological-cancer-treatment-by-piedmont-liguria-and-valle-d-aosta-group-of-airo-italian-association-of-radiation-oncology
#16
Gabriella Cattari, Elena Delmastro, Sara Bresciani, Sergio Gribaudo, Antonella Melano, Flavio Giannelli, Maria Tessa, Renato Chiarlone, Tindaro Scolaro, Marco Krengli, Alessandro Urgesi, Pietro Gabriele
PURPOSE: We focused the attention on radiation therapy practices about the gynecological malignancies in Piedmont, Liguria, and Valle d'Aosta to know the current treatment practice and to improve the quality of care. MATERIAL AND METHODS: We proposed a cognitive survey to evaluate the standard practice patterns for gynecological cancer management, adopted from 2012 to 2014 by radiotherapy (RT) centers with a large amount of gynecological cancer cases. There were three topics: 1...
April 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/27158206/significance-of-functional-hepatic-resection-rate-calculated-using-3d-ct-99m-tc-galactosyl-human-serum-albumin-single-photon-emission-computed-tomography-fusion-imaging
#17
Yosuke Tsuruga, Toshiya Kamiyama, Hirofumi Kamachi, Shingo Shimada, Kenji Wakayama, Tatsuya Orimo, Tatsuhiko Kakisaka, Hideki Yokoo, Akinobu Taketomi
AIM: To evaluate the usefulness of the functional hepatic resection rate (FHRR) calculated using 3D computed tomography (CT)/(99m)Tc-galactosyl-human serum albumin (GSA) single-photon emission computed tomography (SPECT) fusion imaging for surgical decision making. METHODS: We enrolled 57 patients who underwent bi- or trisectionectomy at our institution between October 2013 and March 2015. Of these, 26 patients presented with hepatocellular carcinoma, 12 with hilar cholangiocarcinoma, six with intrahepatic cholangiocarcinoma, four with liver metastasis, and nine with other diseases...
May 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27022486/prostate-radiotherapy-in-the-era-of-advanced-imaging-and-precision-medicine
#18
REVIEW
Caleb R Dulaney, Daniel O Osula, Eddy S Yang, Soroush Rais-Bahrami
Tremendous technological advancements in prostate radiotherapy have decreased treatment toxicity and improved clinical outcomes for men with prostate cancer. While these advances have allowed for significant treatment volume reduction and whole-organ dose escalation, further improvement in prostate radiotherapy has been limited by classic techniques for diagnosis and risk stratification. Developments in prostate imaging, image-guided targeted biopsy, next-generation gene expression profiling, and targeted molecular therapies now provide information to stratify patients and select treatments based on tumor biology...
2016: Prostate Cancer
https://www.readbyqxmd.com/read/26994828/analysis-of-nodal-coverage-utilizing-image-guided-radiation-therapy-for-primary-gynecologic-tumor-volumes
#19
Faisal Ahmed, Vikren Sarkar, David K Gaffney, Bill Salter, Matthew M Poppe
PURPOSE: To evaluate radiation dose delivered to pelvic lymph nodes, if daily Image Guided Radiation Therapy (IGRT) was implemented with treatment shifts based on the primary site (primary clinical target volume [CTV]). Our secondary goal was to compare dosimetric coverage with patient outcomes. MATERIALS AND METHODS: A total of 10 female patients with gynecologic malignancies were evaluated retrospectively after completion of definitive intensity-modulated radiation therapy (IMRT) to their pelvic lymph nodes and primary tumor site...
2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/26821513/-novel-strategy-in-the-radiotherapy-of-metastatic-brain-tumors-simultaneous-whole-brain-radiotherapy-and-integrated-stereotactic-radiosurgery
#20
Judit Kalincsák, Zoltán László, Zsolt Sebestyén, Péter Kovács, Zsolt Horváth, Tamás Dóczi, Mangel László
BACKGROUND AND PURPOSE: Treatment of central nervous system (CNS) tumors has always played an important role in development of radiotherapy techniques. Precise patient immobilisation, non-coplanar field arrangement, conformal treatment, arc therapy, radiosurgery, application of image fusion to radiation planning or re-irradiation were first introduced into clinical routine in the treatment of brain tumors. METHODS: A modern multifunctional radiation instrument, Novalis TX has been installed at the University of Pécs two years ago...
November 30, 2015: Ideggyógyászati Szemle
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