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Image fusion radiation therapy

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https://www.readbyqxmd.com/read/29770311/-super-active-surveillance-mri-ultrasound-fusion-biopsy-and-ablation-for-less-invasive-management-of-prostate-cancer
#1
REVIEW
Jonathan B Bloom, Samuel A Gold, Graham R Hale, Kareem N Rayn, Vikram K Sabarwal, Ivane Bakhutashvili, Vladimir Valera, Baris Turkbey, Peter A Pinto, Bradford J Wood
Multiparametric magnetic resonance imaging (mpMRI) of the prostate has allowed clinicians to better visualize and target suspicious lesions during biopsy. Targeted prostate biopsies give a more accurate representation of the true cancer volume and stage so that appropriate treatment or active surveillance can be selected. Advances in technology have led to the development of MRI and ultrasound fusion platforms used for targeted biopsies, monitoring cancer progression, and more recently for the application of focal therapy...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29748100/impact-of-magnetic-resonance-imaging-on-gross-tumor-volume-delineation-in-non-spine-bony-metastasis-treated-with-stereotactic-body-radiation-therapy
#2
Srinivas Raman, Lee Chin, Darby Erler, Eshetu G Atenafu, Patrick Cheung, William Chu, Hans Chung, Andrew Loblaw, Ian Poon, Joel Rubenstein, Hany Soliman, Arjun Sahgal, Chia-Lin Tseng
PURPOSE: This study investigates the inter-observer variability of contouring non-spine bone metastases using the planning CT alone vs. the addition of MRI T1 and T2 imaging sequences. METHODS AND MATERIALS: 10 cases of non-spine bone metastases treated with SBRT at our institution were selected. The gross tumor volume (GTV) for each case was delineated by six SBRT radiation oncologists (RO) and one diagnostic radiologist (DR) on the treatment planning CT. After a minimum of three months, each case was re-contoured on the CT fused with a MRI T1 sequence followed by a MRI T2 sequence...
March 17, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29706305/impact-of-rectal-distension-on-prostate-cbct-based-positioning-assessed-with-6-degrees-of-freedom-couch
#3
Julien Charret, Julia Salleron, Magali Quivrin, Frédéric Mazoyer, Paul Lesueur, Etienne Martin, Didier Peiffert, Gilles Créhange
INTRODUCTION: Prostate requires a daily correction of its 3-dimensional position in relation with rectal distension. In this study, we sought to determine whether rectal distension with respect to the rectal behavior might have an impact on prostate translations and/or rotations during prostate image guided radiation therapy using a 6 degrees-of-freedom (DOF) couch. METHODS AND MATERIALS: We reviewed the data from 39 patients with localized prostate cancer treated with protracted external radiation therapy using a 6 DOF couch...
March 9, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29588620/in-room-ultrasound-fusion-combined-with-fully-compatible-3d-printed-holding-arm-rethinking-interventional-mri
#4
Michael Friebe, Juan Sanchez, Sathish Balakrishnan, Alfredo Illanes, Yeshaswini Nagaraj, Robert Odenbach, Marwah Matooq, Gabriele Krombach, Michael Vogele, Axel Boese
There is no real need to discuss the potential advantages - mainly the excellent soft tissue contrast, nonionizing radiation, flow, and molecular information - of magnetic resonance imaging (MRI) as an intraoperative diagnosis and therapy system particularly for neurological applications and oncological therapies. Difficult patient access in conventional horizontal-field superconductive magnets, very high investment and operational expenses, and the need for special nonferromagnetic therapy tools have however prevented the widespread use of MRI as imaging and guidance tool for therapy purposes...
2018: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/29556300/a-dosimetric-phantom-study-of-thoracic-radiotherapy-based-on-three-dimensional-modeling-of-mediastinal-lymph-nodes
#5
Ji-Bin Zhang, Li-Rong Zhao, Tian-Xiang Cui, Xie-Wan Chen, Qiao Yang, Yi-Bing Zhou, Zheng-Tang Chen, Shao-Xiang Zhang, Jian-Guo Sun
The aim of the present study was to investigate the optimal strategy and dosimetric measurement of thoracic radiotherapy based on three-dimensional (3D) modeling of mediastinal lymph nodes (MLNs). A 3D model of MLNs was constructed from a Chinese Visible Human female dataset. Image registration and fusion between reconstructed MLNs and original chest computed tomography (CT) images was conducted in the Eclipse™ treatment planning system (TPS). There were three plans, including 3D conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT), which were designed based on 10 cases of simulated lung lesions (SLLs) and MLNs...
April 2018: Oncology Letters
https://www.readbyqxmd.com/read/29505514/lumbar-laminotomy-and-replantation-for-the-treatment-of-adult-spinal-epidermoid-cyst-a-case-report
#6
Yong-Peng Lin, Yong-Jin Li, Bo-Lai Chen, Yu-Hai Guo
RATIONALE: Adult spinal epidermoid cyst (SEC) is a rare tumor. Lumbar laminectomy and tumor removal was a routine surgical procedure for adult spinal epidermoid cyst according to the literature, but postoperative lumbar instability and intractable low back pain may occur. In this study, we presented a brief report of an adult lumbar epidermoid cyst and introduced another surgical approach. PATIENT CONCERNS: This 28-year-old woman has been complaining of the severe right buttock pain and right thigh radiating pain for half a year...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29474100/cervical-myelopathy-causing-numbness-and-paresthesias-in-lower-extremities-a-case-report-identifying-the-cause-of-a-false-positive-sharp-purser-test
#7
Cody J Mansfield
INTRODUCTION: The patient was referred to an outpatient physical therapy clinic for lumbar radiculopathy by a primary care physician and subsequently referred for imaging due to suspicion of cervical myelopathy. The case highlights the clinical reasoning of the physical therapist differentiating between lumbar stenosis, cervical myelopathy, and upper cervical instability. To the author's knowledge, this is the only case report in the literature to describe the mechanism that could underpin a false positive Sharp-Purser test (SPT)...
February 23, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29372848/hepatic-epithelioid-hemangioendothelioma
#8
Lynette L Studer, Dale M Selby
Epithelioid hemangioendothelioma is a rare vascular tumor, composed of epithelioid and histiocytoid vascular endothelial cells in myxoid or fibrotic stroma, which can arise in multiple locations throughout the body. In the liver, this neoplasm usually presents on imaging as an incidental finding of multifocal, heterogeneously enhancing nodules in both lobes or presents clinically with nonspecific abdominal symptoms. Histologically, the tumor has been mistaken for metastatic carcinoma, angiosarcoma, hepatocellular carcinoma, and cholangiocarcinoma...
February 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29221343/adult-onset-langerhans-cell-histiocytosis-of-the-sternum
#9
Yi-Jhih Huang, Kuan-Hsun Lin, Tai-Kuang Chao, Tsai-Wang Huang, Hsu-Kai Huang
Langerhans cell histiocytosis (LCH) is a rare disease with uncertain etiology that is more prevalent in children. LCH typically invades skeletal systems, but in rare cases, it has been reported in the ribs or sternum. Optimal treatment choices for single-site, skeletal LCH are still undefined. We report a case of adult-onset LCH of the sternum. The range of surrounding soft tissue invasion was confirmed by three-dimensional fusion and reconstruction of chest computed tomography and magnetic resonance images...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29195619/pet-ct-in-radiation-therapy-planning
#10
REVIEW
Lena Specht, Anne Kiil Berthelsen
Radiation therapy (RT) is an important component of the management of lymphoma patients. Most lymphomas are metabolically active and accumulate 18 F-fluorodeoxyglucose (FDG). Positron emission tomography with computer tomography (PET/CT) imaging using FDG is used routinely in staging and treatment evaluation. FDG-PET/CT imaging is now also used routinely for contouring the target for RT, and has been shown to change the irradiated volume significantly compared with CT imaging alone. Modern advanced imaging techniques with image fusion and motion management in combination with modern highly conformal RT techniques have increased the precision of RT, and have made it possible to reduce dramatically the risks of long-term side effects of treatment while maintaining the high cure rates for these diseases...
January 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29019641/spine-conditions-lumbar-spinal-stenosis
#11
REVIEW
Steven D Trigg, Zachary Devilbiss
Lumbar spinal stenosis (LSS) is a frequent cause of chronic low back and lower extremity pain in older patients. Symptomatic LSS typically is described as neurogenic claudication consisting of pain, weakness, numbness, and/or fatigue arising in the back and radiating into the buttock, thigh, or lower leg. The diagnosis is complicated by lack of reliable clinical or x-ray criteria. North American Spine Society guidelines recommend magnetic resonance imaging study without contrast to confirm anatomic narrowing of the spinal canal or nerve root impingement...
October 2017: FP Essentials
https://www.readbyqxmd.com/read/28844603/t2-star-weighted-angiography-swan-allows-to-concomitantly-assess-the-prostate-contour-while-detecting-fiducials-before-mr-based-intensity-modulated-radiation-therapy-in-prostate-carcinoma
#12
Pierre-Antoine Dirajlal, Eva Jambon, Agnes Albat-Esquirou, Chloe Galmiche, Jean-Christophe Bernhard, Nicolas Grenier, Thibaud Haaser, François H Cornelis
PURPOSE: To evaluate the performance of T2 star-weighted angiography (SWAN) to concomitantly assess the prostate contour while detecting fiducials before magnetic resonance (MR)-based intensity-modulated radiation therapy (IMRT) in prostate carcinoma. MATERIALS AND METHODS: Forty patients (mean age: 73.1 ± 7.5 years; average Gleason score: 7 ± 1; average prostate-specific antigen: 14.7 ± 11.6 ng/mL) underwent MR and computed tomography imaging before fiducial-based IMRT...
January 2018: Academic Radiology
https://www.readbyqxmd.com/read/28818321/influence-of-computed-tomography-contrast-agent-on-radiotherapy-dose-calculation-for-pancreatic-carcinoma-a-dosimetric-study-based-on-tomotherapy-and-volumetric-modulated-arc-therapy-techniques
#13
Feng Zhu, Weizhang Wu, Fuhai Zhu, Yong Wang, Yingjie Wang, Tingyi Xia
The main purpose of our investigation was to quantify the dosimetric influence of intravenous contrast agent for pancreatic cancer radiotherapy treatment. This study focused on complex modulated irradiation techniques of tomotherapy (TOMO) and volumetric-modulated arc therapy (VMAT) to investigate if novel conformal treatment methods could reduce the influence of contrast agent. In our study, patients with pancreatic cancer were enrolled to have 2 computed tomography (CT) scans in the same position without and with intravenous contrast agent for treatment planning...
August 14, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28816167/variabilities-of-magnetic-resonance-imaging-computed-tomography-and-positron-emission-tomography-computed-tomography-based-tumor-and-lymph-node-delineations-for-lung-cancer-radiation-therapy-planning
#14
COMPARATIVE STUDY
Kishor Karki, Siddharth Saraiya, Geoffrey D Hugo, Nitai Mukhopadhyay, Nuzhat Jan, Jessica Schuster, Matthew Schutzer, Lester Fahrner, Robert Groves, Kathryn M Olsen, John C Ford, Elisabeth Weiss
PURPOSE: To investigate interobserver delineation variability for gross tumor volumes of primary lung tumors and associated pathologic lymph nodes using magnetic resonance imaging (MRI), and to compare the results with computed tomography (CT) alone- and positron emission tomography (PET)-CT-based delineations. METHODS AND MATERIALS: Seven physicians delineated the tumor volumes of 10 patients for the following scenarios: (1) CT only, (2) PET-CT fusion images registered to CT ("clinical standard"), and (3) postcontrast T1-weighted MRI registered with diffusion-weighted MRI...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28781797/effect-of-modern-high-quality-prostate-intensity-modulated-radiation-therapy-on-outcome-evidence-from-a-community-radiation-oncology-program
#15
Johnny Kao, Amanda Zucker, Jonathan Timmins, Shankar Taramangalam, Jeffrey Pettit, Aaron J Woodall, Edward Loizides, Andrew T Wong
Radiation technique for prostate cancer has continuously evolved over the past several decades. The aim of the present study was to describe the effects of implementing modern prostate intensity-modulated radiation therapy (M-IMRT) on dosimetry and outcome. Between January 2010 and April 2012, 48 consecutive patients were treated with conventional prostate IMRT (C-IMRT) to a dose of 81 Gy. Between May 2012 and April 2015, 50 consecutive patients were treated with M-IMRT to the entire prostate to a dose of 75...
August 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28740937/impact-of-prone-versus-supine-positioning-on-small-bowel-dose-with-pelvic-intensity-modulated-radiation-therapy
#16
Victor J Gonzalez, Craig R Hullett, Lindsay Burt, Prema Rassiah-Szegedi, Vikren Sarkar, Jonathan D Tward, Lisa J Hazard, Y Jessica Huang, Bill J Salter, David K Gaffney
PURPOSE: To report the results of a prospective study that compares small bowel doses during prone and supine pelvic intensity modulated radiation therapy. METHODS AND MATERIALS: Ten patients receiving pelvic radiation therapy each had 2 intensity modulated radiation therapy plans generated: supine and prone on a belly board (PBB). Computed tomography on rails was performed weekly throughout treatment in both positions (10 scans per patient). After image fusion, doses to small bowel (SB) loops and clinical target volume were calculated for each scan...
April 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28736864/brain-tumor-segmentation-using-holistically-nested-neural-networks-in-mri-images
#17
Ying Zhuge, Andra V Krauze, Holly Ning, Jason Y Cheng, Barbara C Arora, Kevin Camphausen, Robert W Miller
PURPOSE: Gliomas are rapidly progressive, neurologically devastating, largely fatal brain tumors. Magnetic resonance imaging (MRI) is a widely used technique employed in the diagnosis and management of gliomas in clinical practice. MRI is also the standard imaging modality used to delineate the brain tumor target as part of treatment planning for the administration of radiation therapy. Despite more than 20 yr of research and development, computational brain tumor segmentation in MRI images remains a challenging task...
October 2017: Medical Physics
https://www.readbyqxmd.com/read/28694116/effect-of-bladder-distension-on-doses-to-organs-at-risk-in-pulsed-dose-rate-3d-image-guided-adaptive-brachytherapy-for-locally-advanced-cervical-cancer
#18
Jean Philippe Nesseler, Claire Charra-Brunaud, Julia Salleron, Jean François Py, Andres Huertas, Emilie Meknaci, Florent Courrech, Didier Peiffert, Sophie Renard-Oldrini
PURPOSE: To evaluate the impact of bladder distension on doses to organs at risk in patients treated with 3D image-guided adaptive pulsed-dose-rate (PDR) brachytherapy (BT) for locally advanced cervical cancer. METHODS AND MATERIALS: Twenty-two patients who had previously been treated by external beam radiation therapy (EBRT), underwent BT treatment planning to a pelvic MRI (or a CT scan in case of contraindication) after their bladder was filled with 100 cc of physiological saline (full bladder)...
July 7, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28533050/dual-core-steered-non-rigid-registration-for-multi-modal-images-via-bi-directional-image-synthesis
#19
Xiaohuan Cao, Jianhua Yang, Yaozong Gao, Yanrong Guo, Guorong Wu, Dinggang Shen
In prostate cancer radiotherapy, computed tomography (CT) is widely used for dose planning purposes. However, because CT has low soft tissue contrast, it makes manual contouring difficult for major pelvic organs. In contrast, magnetic resonance imaging (MRI) provides high soft tissue contrast, which makes it ideal for accurate manual contouring. Therefore, the contouring accuracy on CT can be significantly improved if the contours in MRI can be mapped to CT domain by registering MRI with CT of the same subject, which would eventually lead to high treatment efficacy...
May 13, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28472175/characterization-of-3d-printing-techniques-toward-patient-specific-quality-assurance-spine-shaped-phantom-for-stereotactic-body-radiation-therapy
#20
Min-Joo Kim, Seu-Ran Lee, Min-Young Lee, Jason W Sohn, Hyong Geon Yun, Joon Yong Choi, Sang Won Jeon, Tae Suk Suh
Development and comparison of spine-shaped phantoms generated by two different 3D-printing technologies, digital light processing (DLP) and Polyjet has been purposed to utilize in patient-specific quality assurance (QA) of stereotactic body radiation treatment. The developed 3D-printed spine QA phantom consisted of an acrylic body phantom and a 3D-printed spine shaped object. DLP and Polyjet 3D printers using a high-density acrylic polymer were employed to produce spine-shaped phantoms based on CT images. Image fusion was performed to evaluate the reproducibility of our phantom, and the Hounsfield units (HUs) were measured based on each CT image...
2017: PloS One
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