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Image fusion radiation therapy

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https://www.readbyqxmd.com/read/29221343/adult-onset-langerhans-cell-histiocytosis-of-the-sternum
#1
Yi-Jhih Huang, Kuan-Hsun Lin, Tai-Kuang Chao, Tsai-Wang Huang, Hsu-Kai Huang
Langerhans cell histiocytosis (LCH) is a rare disease with uncertain etiology that is more prevalent in children. LCH typically invades skeletal systems, but in rare cases, it has been reported in the ribs or sternum. Optimal treatment choices for single-site, skeletal LCH are still undefined. We report a case of adult-onset LCH of the sternum. The range of surrounding soft tissue invasion was confirmed by three-dimensional fusion and reconstruction of chest computed tomography and magnetic resonance images...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29195619/pet-ct-in-radiation-therapy-planning
#2
REVIEW
Lena Specht, Anne Kiil Berthelsen
Radiation therapy (RT) is an important component of the management of lymphoma patients. Most lymphomas are metabolically active and accumulate 18F-fluorodeoxyglucose (FDG). Positron emission tomography with computer tomography (PET/CT) imaging using FDG is used routinely in staging and treatment evaluation. FDG-PET/CT imaging is now also used routinely for contouring the target for RT, and has been shown to change the irradiated volume significantly compared with CT imaging alone. Modern advanced imaging techniques with image fusion and motion management in combination with modern highly conformal RT techniques have increased the precision of RT, and have made it possible to reduce dramatically the risks of long-term side effects of treatment while maintaining the high cure rates for these diseases...
January 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29019641/spine-conditions-lumbar-spinal-stenosis
#3
REVIEW
Steven D Trigg, Zachary Devilbiss
Lumbar spinal stenosis (LSS) is a frequent cause of chronic low back and lower extremity pain in older patients. Symptomatic LSS typically is described as neurogenic claudication consisting of pain, weakness, numbness, and/or fatigue arising in the back and radiating into the buttock, thigh, or lower leg. The diagnosis is complicated by lack of reliable clinical or x-ray criteria. North American Spine Society guidelines recommend magnetic resonance imaging study without contrast to confirm anatomic narrowing of the spinal canal or nerve root impingement...
October 2017: FP Essentials
https://www.readbyqxmd.com/read/28844603/t2-star-weighted-angiography-swan-allows-to-concomitantly-assess-the-prostate-contour-while-detecting-fiducials-before-mr-based-intensity-modulated-radiation-therapy-in-prostate-carcinoma
#4
Pierre-Antoine Dirajlal, Eva Jambon, Agnes Albat-Esquirou, Chloe Galmiche, Jean-Christophe Bernhard, Nicolas Grenier, Thibaud Haaser, François H Cornelis
PURPOSE: To evaluate the performance of T2 star-weighted angiography (SWAN) to concomitantly assess the prostate contour while detecting fiducials before magnetic resonance (MR)-based intensity-modulated radiation therapy (IMRT) in prostate carcinoma. MATERIALS AND METHODS: Forty patients (mean age: 73.1 ± 7.5 years; average Gleason score: 7 ± 1; average prostate-specific antigen: 14.7 ± 11.6 ng/mL) underwent MR and computed tomography imaging before fiducial-based IMRT...
August 22, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28818321/influence-of-computed-tomography-contrast-agent-on-radiotherapy-dose-calculation-for-pancreatic-carcinoma-a-dosimetric-study-based-on-tomotherapy-and-volumetric-modulated-arc-therapy-techniques
#5
Feng Zhu, Weizhang Wu, Fuhai Zhu, Yong Wang, Yingjie Wang, Tingyi Xia
The main purpose of our investigation was to quantify the dosimetric influence of intravenous contrast agent for pancreatic cancer radiotherapy treatment. This study focused on complex modulated irradiation techniques of tomotherapy (TOMO) and volumetric-modulated arc therapy (VMAT) to investigate if novel conformal treatment methods could reduce the influence of contrast agent. In our study, patients with pancreatic cancer were enrolled to have 2 computed tomography (CT) scans in the same position without and with intravenous contrast agent for treatment planning...
August 14, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28816167/variabilities-of-magnetic-resonance-imaging-computed-tomography-and-positron-emission-tomography-computed-tomography-based-tumor-and-lymph-node-delineations-for-lung-cancer-radiation-therapy-planning
#6
COMPARATIVE STUDY
Kishor Karki, Siddharth Saraiya, Geoffrey D Hugo, Nitai Mukhopadhyay, Nuzhat Jan, Jessica Schuster, Matthew Schutzer, Lester Fahrner, Robert Groves, Kathryn M Olsen, John C Ford, Elisabeth Weiss
PURPOSE: To investigate interobserver delineation variability for gross tumor volumes of primary lung tumors and associated pathologic lymph nodes using magnetic resonance imaging (MRI), and to compare the results with computed tomography (CT) alone- and positron emission tomography (PET)-CT-based delineations. METHODS AND MATERIALS: Seven physicians delineated the tumor volumes of 10 patients for the following scenarios: (1) CT only, (2) PET-CT fusion images registered to CT ("clinical standard"), and (3) postcontrast T1-weighted MRI registered with diffusion-weighted MRI...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28781797/effect-of-modern-high-quality-prostate-intensity-modulated-radiation-therapy-on-outcome-evidence-from-a-community-radiation-oncology-program
#7
Johnny Kao, Amanda Zucker, Jonathan Timmins, Shankar Taramangalam, Jeffrey Pettit, Aaron J Woodall, Edward Loizides, Andrew T Wong
Radiation technique for prostate cancer has continuously evolved over the past several decades. The aim of the present study was to describe the effects of implementing modern prostate intensity-modulated radiation therapy (M-IMRT) on dosimetry and outcome. Between January 2010 and April 2012, 48 consecutive patients were treated with conventional prostate IMRT (C-IMRT) to a dose of 81 Gy. Between May 2012 and April 2015, 50 consecutive patients were treated with M-IMRT to the entire prostate to a dose of 75...
August 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28740937/impact-of-prone-versus-supine-positioning-on-small-bowel-dose-with-pelvic-intensity-modulated-radiation-therapy
#8
Victor J Gonzalez, Craig R Hullett, Lindsay Burt, Prema Rassiah-Szegedi, Vikren Sarkar, Jonathan D Tward, Lisa J Hazard, Y Jessica Huang, Bill J Salter, David K Gaffney
PURPOSE: To report the results of a prospective study that compares small bowel doses during prone and supine pelvic intensity modulated radiation therapy. METHODS AND MATERIALS: Ten patients receiving pelvic radiation therapy each had 2 intensity modulated radiation therapy plans generated: supine and prone on a belly board (PBB). Computed tomography on rails was performed weekly throughout treatment in both positions (10 scans per patient). After image fusion, doses to small bowel (SB) loops and clinical target volume were calculated for each scan...
April 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28736864/brain-tumor-segmentation-using-holistically-nested-neural-networks-in-mri-images
#9
Ying Zhuge, Andra V Krauze, Holly Ning, Jason Y Cheng, Barbara C Arora, Kevin Camphausen, Robert W Miller
PURPOSE: Gliomas are rapidly progressive, neurologically devastating, largely fatal brain tumors. Magnetic resonance imaging (MRI) is a widely used technique employed in the diagnosis and management of gliomas in clinical practice. MRI is also the standard imaging modality used to delineate the brain tumor target as part of treatment planning for the administration of radiation therapy. Despite more than 20 yr of research and development, computational brain tumor segmentation in MRI images remains a challenging task...
October 2017: Medical Physics
https://www.readbyqxmd.com/read/28694116/effect-of-bladder-distension-on-doses-to-organs-at-risk-in-pulsed-dose-rate-3d-image-guided-adaptive-brachytherapy-for-locally-advanced-cervical-cancer
#10
Jean Philippe Nesseler, Claire Charra-Brunaud, Julia Salleron, Jean François Py, Andres Huertas, Emilie Meknaci, Florent Courrech, Didier Peiffert, Sophie Renard-Oldrini
PURPOSE: To evaluate the impact of bladder distension on doses to organs at risk in patients treated with 3D image-guided adaptive pulsed-dose-rate (PDR) brachytherapy (BT) for locally advanced cervical cancer. METHODS AND MATERIALS: Twenty-two patients who had previously been treated by external beam radiation therapy (EBRT), underwent BT treatment planning to a pelvic MRI (or a CT scan in case of contraindication) after their bladder was filled with 100 cc of physiological saline (full bladder)...
July 7, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28533050/dual-core-steered-non-rigid-registration-for-multi-modal-images-via-bi-directional-image-synthesis
#11
Xiaohuan Cao, Jianhua Yang, Yaozong Gao, Yanrong Guo, Guorong Wu, Dinggang Shen
In prostate cancer radiotherapy, computed tomography (CT) is widely used for dose planning purposes. However, because CT has low soft tissue contrast, it makes manual contouring difficult for major pelvic organs. In contrast, magnetic resonance imaging (MRI) provides high soft tissue contrast, which makes it ideal for accurate manual contouring. Therefore, the contouring accuracy on CT can be significantly improved if the contours in MRI can be mapped to CT domain by registering MRI with CT of the same subject, which would eventually lead to high treatment efficacy...
May 13, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28472175/characterization-of-3d-printing-techniques-toward-patient-specific-quality-assurance-spine-shaped-phantom-for-stereotactic-body-radiation-therapy
#12
Min-Joo Kim, Seu-Ran Lee, Min-Young Lee, Jason W Sohn, Hyong Geon Yun, Joon Yong Choi, Sang Won Jeon, Tae Suk Suh
Development and comparison of spine-shaped phantoms generated by two different 3D-printing technologies, digital light processing (DLP) and Polyjet has been purposed to utilize in patient-specific quality assurance (QA) of stereotactic body radiation treatment. The developed 3D-printed spine QA phantom consisted of an acrylic body phantom and a 3D-printed spine shaped object. DLP and Polyjet 3D printers using a high-density acrylic polymer were employed to produce spine-shaped phantoms based on CT images. Image fusion was performed to evaluate the reproducibility of our phantom, and the Hounsfield units (HUs) were measured based on each CT image...
2017: PloS One
https://www.readbyqxmd.com/read/28397316/proposed-expansion-margins-for-planning-organ-at-risk-volume-for-lenses-during-radiation-therapy-of-the-nasal-cavity-in-dogs-and-cats
#13
Zaki Jafry, Arnon Gal, Andre Fleck, Johnson Darko, Valerie J Poirier
Radiation therapy protocols for the feline or canine nasal cavity can damage epithelial cells of the posterior pole of the lens and lead to the development of cataracts. Aims of this retrospective, descriptive study were to calculate movements of the lens during radiation therapy of the nasal cavity in a sample of cats and dogs, and to propose species-specific expansion margins for planning organ at risk volume (PRV) to minimize radiation doses to the lens. All included patients were immobilized with an indexed bite block and positioned in a vacuum positioning cushion for head irradiation...
April 11, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28376237/use-of-image-registration-and-fusion-algorithms-and-techniques-in-radiotherapy-report-of-the-aapm-radiation-therapy-committee-task-group-no-132
#14
Kristy K Brock, Sasa Mutic, Todd R McNutt, Hua Li, Marc L Kessler
Image registration and fusion algorithms exist in almost every software system that creates or uses images in radiotherapy. Most treatment planning systems support some form of image registration and fusion to allow the use of multimodality and time-series image data and even anatomical atlases to assist in target volume and normal tissue delineation. Treatment delivery systems perform registration and fusion between the planning images and the in-room images acquired during the treatment to assist patient positioning...
July 2017: Medical Physics
https://www.readbyqxmd.com/read/28333017/effect-of-prostate-magnetic-resonance-imaging-ultrasound-fusion-guided-biopsy-on-radiation-treatment-recommendations
#15
Aaron Reed, Luca F Valle, Uma Shankavaram, Andra Krauze, Aradhana Kaushal, Erica Schott, Theresa Cooley-Zgela, Bradford Wood, Peter Pinto, Peter Choyke, Baris Turkbey, Deborah E Citrin
PURPOSE: Targeted magnetic resonance imaging (MRI)/ultrasound fusion prostate biopsy (MRI-Bx) has recently been compared with the standard of care extended sextant ultrasound-guided prostate biopsy (SOC-Bx), with the former associated with an increased rate of detection of clinically significant prostate cancer. The present study sought to determine the influence of MRI-Bx on radiation therapy and androgen deprivation therapy (ADT) recommendations. METHODS AND MATERIALS: All patients who had received radiation treatment and had undergone SOC-Bx and MRI-Bx at our institution were included...
April 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28115952/salvage-high-dose-rate-brachytherapy-for-histologically-confirmed-macroscopic-local-relapsed-prostate-cancer-after-radical-prostatectomy
#16
David Buchser, Alfonso Gomez-Iturriaga, J Ignacio Rodriguez Melcon, Francisco Casquero, Roberto Llarena, Jon Cacicedo, Pedro Bilbao
PURPOSE: To evaluate the feasibility of the use of real-time magnetic resonance imaging (MRI)-transrectal ultrasound (TRUS) fusion guided high-dose-rate brachytherapy (HDR-BT) +/- external beam radiation therapy (EBRT) in patients with histologically-proven local relapse after radical prostatectomy. MATERIAL AND METHODS: We retrospectively reviewed 13 patients treated with real-time MRI-TRUS fusion HDR-BT for a local relapse of prostate cancer after radical surgery...
December 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28048721/su-f-j-222-using-pet-imaging-to-evaluate-proliferation-and-blood-flow-in-irradiated-and-non-irradiated-bone-marrow-1-year-after-chemoradiation-therapy
#17
S McGuire, L Ponto, Y Menda
PURPOSE: To compare proliferation and blood flow in pelvic and thoracic bone marrow 1 year after pelvic chemoradiation. METHODS: Sixteen pelvic cancer patients were enrolled in an IRB-approved protocol to acquire FLT PET images during radiation therapy simulation (baseline) and 1 year after chemoradiation therapy. Three subjects also had optional O-15 water PET images acquired 1 year after chemoradiation therapy. Baseline FLT PET images were used to create IMRT plans to spare pelvic bone marrow identified as regions with FLT SUV ≥ 2 without compromising PTV coverage or OAR sparing...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048133/su-f-j-113-multi-atlas-based-automatic-organ-segmentation-for-lung-radiotherapy-planning
#18
J Kim, J Han, S Ailawadi, J Baker, A Hsia, Z Xu, S Ryu
PURPOSE: Normal organ segmentation is one time-consuming and labor-intensive step for lung radiotherapy treatment planning. The aim of this study is to evaluate the performance of a multi-atlas based segmentation approach for automatic organs at risk (OAR) delineation. METHODS: Fifteen Lung stereotactic body radiation therapy patients were randomly selected. Planning CT images and OAR contours of the heart - HT, aorta - AO, vena cava - VC, pulmonary trunk - PT, and esophagus - ES were exported and used as reference and atlas sets...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047834/su-c-bra-04-automated-segmentation-of-head-and-neck-ct-images-for-radiotherapy-treatment-planning-via-multi-atlas-machine-learning-maml
#19
X Ren, G Sharp, H Gao
PURPOSE: Accurate image segmentation is a crucial step during image guided radiation therapy. This work proposes multi-atlas machine learning (MAML) algorithm for automated segmentation of head-and-neck CT images. METHODS: As the first step, the algorithm utilizes normalized mutual information as similarity metric, affine registration combined with multiresolution B-Spline registration, and then fuses together using the label fusion strategy via Plastimatch. As the second step, the following feature selection strategy is proposed to extract five feature components from reference or atlas images: intensity (I), distance map (D), box (B), center of gravity (C) and stable point (S)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047471/su-f-p-23-setup-uncertainties-for-the-lung-stereotactic-body-radiation-therapy
#20
Q Zhang, Y Cao, A Jamshidi, P Vigneri, C Madu, L Potters, E Klein
PURPOSE: The Exactrack X-ray system with six degree-of-freedom (6DoF) adjustment ability can be used for setup of lung stereotactic body radiation therapy. The setup uncertainties from ExacTrack 6D system were analyzed. METHODS: The Exactrack X-ray 6D image guided radiotherapy system is used in our clinic. The system is an integration of 2 subsystems: (1): an infrared based optical position system and (2) a radiography kV x-ray imaging system. The infrared system monitors reflective body markers on the patient's skin to assistant in the initial setup...
June 2016: Medical Physics
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