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https://www.readbyqxmd.com/read/28549161/cigarette-smoking-cessation-intervention-for-buprenorphine-treatment-patients
#1
Sharon M Hall, Gary Humfleet, James Gasper, Kevin L Delucchi, David Hersh, Joseph Guydish
Introduction: Patients receiving Medication Assisted Therapy (MAT) for opioid use disorder have high cigarette smoking rates. Cigarette smoking interventions have had limited success. We evaluated an intervention to increase cigarette abstinence rates in patients receiving buprenorphine-assisted therapy. Methods: Cigarette smokers (N=175; 78% male; 69% Caucasian; 20% Hispanic), recruited from a buprenorphine clinic were randomly assigned to either an extended innovative system intervention (E-ISI) or to Standard Treatment Control (STC)...
May 26, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28548223/cannabis-smoking-and-cardiovascular-health-it-s-complicated
#2
M R Piano
Many states have legalized cannabis use for treatment of certain medical conditions or have legalized cannabis for recreational use. Consequently, cannabis use prevalence has escalated, giving rise to concerns about potential health effects. Cannabis smoking remains the most prevalent route of administration and is associated with inhalation of chemical toxicants. The aim of this article is to summarize the effects of cannabis smoking on the vasculature and occurrence of cardiovascular (CV) events such as myocardial infarction (MI) and stroke...
May 26, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28534260/pharmacogenetics-of-cannabinoids
#3
Szymon Hryhorowicz, Michal Walczak, Oliwia Zakerska-Banaszak, Ryszard Słomski, Marzena Skrzypczak-Zielińska
Although the application of medical marijuana and cannabinoid drugs is controversial, it is a part of modern-day medicine. The list of diseases in which cannabinoids are promoted as a treatment is constantly expanding. Cases of significant improvement in patients with a very poor prognosis of glioma or epilepsy have already been described. However, the occurrence of side effects is still difficult to estimate, and the current knowledge of the therapeutic effects of cannabinoids is still insufficient. In our opinion, the answers to many questions and concerns regarding the medical use of cannabis can be provided by pharmacogenetics...
May 22, 2017: European Journal of Drug Metabolism and Pharmacokinetics
https://www.readbyqxmd.com/read/28529696/in-silico-gene-expression-profiling-in-cannabis-sativa
#4
Luca Massimino
The cannabis plant and its active ingredients (i.e., cannabinoids and terpenoids) have been socially stigmatized for half a century. Luckily, with more than 430,000 published scientific papers and about 600 ongoing and completed clinical trials, nowadays cannabis is employed for the treatment of many different medical conditions. Nevertheless, even if a large amount of high-throughput functional genomic data exists, most researchers feature a strong background in molecular biology but lack advanced bioinformatics skills...
2017: F1000Research
https://www.readbyqxmd.com/read/28521146/effect-of-continued-cannabis-use-on-medication-adherence-in-the-first-two-years-following-onset-of-psychosis
#5
Tabea Schoeler, Natalia Petros, Marta Di Forti, Ewa Klamerus, Enrico Foglia, Robin Murray, Sagnik Bhattacharyya
Uncertainty exists whether the use of non-prescription psychoactive substances following onset of a first episode of psychosis (FEP), in particular cannabis use, affects medication adherence. Data from FEP patients (N=233) obtained through prospective assessments measured medication adherence and pattern of cannabis and other substance use in the first two years following onset of psychosis. Multiple logistic regression analyses were employed to compare the different substance use groups with regard to risk of medication non-adherence, while controlling for confounders...
May 10, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28516232/-cns-metabolism-in-high-risk-drug-abuse-german-version-insights-gained-from-1-h-and-31-p-mrs-and-pet
#6
REVIEW
S V Bodea
BACKGROUND: High-risk drug consumption is a considerable problem for public health actors in industrialised countries. The latest trends show a market tendency towards diversification and increasing demand for high-purity synthetic drugs. Whilst most consumers seek medical help after cannabis use, it is high-risk drugs like cocaine, heroin and amphetamines that account for most of the 1000 drug-related deaths that occur in Germany every year. PURPOSE: This article presents the most prominent in vivo cerebral metabolic information in cocaine, heroin and methamphetamine users provided by MRI spectroscopy and PET imaging...
May 17, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28501518/cannabidiol-in-medical-marijuana-research-vistas-and-potential-opportunities
#7
REVIEW
Carola Rong, Yena Lee, Nicole E Carmona, Danielle S Cha, Renee-Marie Ragguett, Joshua D Rosenblat, Rodrigo B Mansur, Roger C Ho, Roger S McIntyre
The high and increasing prevalence of medical marijuana consumption in the general population invites the need for quality evidence regarding its safety and efficacy. Herein, we synthesize extant literature pertaining to the phytocannabinoid cannabidiol (CBD) and its brain effects. The principle phytocannabinoid Δ(9)-tetrahydrocannabinol (Δ(9)-THC) and CBD are the major pharmacologically active cannabinoids. The effect of CBD on brain systems as well as on phenomenological measures (e.g. cognitive function) are distinct and in many cases opposite to that of Δ(9)-THC...
May 10, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/28501291/use-and-dependence-on-opioid-drugs-in-the-spanish-population-with-chronic-pain-prevalence-and-differences-according-to-sex
#8
A Coloma-Carmona, J L Carballo, J Rodríguez-Marín, A Pérez-Carbonell
OBJECTIVES: To analyse the prevalence in the use and dependence on opioid drugs in the Spanish population with chronic pain and evaluate the differences according to sex. PATIENTS AND METHODS: The demographic variables, opioid treatment characteristics and use of other substances were assessed in 229 users of opioid drugs. A descriptive bivariate analysis of the data was performed. RESULTS: Forty-six percent of the patients met the criteria of dependence on opioid drugs (Diagnostic and Statistical Manual of Mental Disorders, 4th Edition [DSM-IV-TR])...
May 10, 2017: Revista Clínica Española
https://www.readbyqxmd.com/read/28496355/cannabis-as-a-substitute-for-prescription-drugs-a-cross-sectional-study
#9
James M Corroon, Laurie K Mischley, Michelle Sexton
BACKGROUND: The use of medical cannabis is increasing, most commonly for pain, anxiety and depression. Emerging data suggest that use and abuse of prescription drugs may be decreasing in states where medical cannabis is legal. The aim of this study was to survey cannabis users to determine whether they had intentionally substituted cannabis for prescription drugs. METHODS: A total of 2,774 individuals were a self-selected convenience sample who reported having used cannabis at least once in the previous 90 days...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28494249/evaluation-of-problematic-psychoactive-substances-use-in-people-placed-in-police-custody
#10
Marie Gérardin, Gabriel Guigand, Laura Wainstein, Pascale Jolliet, Caroline Victorri-Vigneau, Renaud Clément
INTRODUCTION AND AIMS: In France, the law states that any person held in custody could be examined by a doctor. The main objective of the medical examination is to give medical evidence of health compatibility with custody. This review identifies health risks such as addictive behaviour. We wanted to know which psychoactive substances are used in this particular population, and how problematic these uses are. DESIGN AND METHODS: A prospective, monocentric, open-ended study conducted via a structured questionnaire was carried out on detainees who reported having taken drugs or illegal substances...
May 2, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28494183/resolution-of-cannabis-hyperemesis-syndrome-with-topical-capsaicin-in-the-emergency-department-a-case-series
#11
Laurel Dezieck, Zachary Hafez, Albert Conicella, Eike Blohm, Mark J O'Connor, Evan S Schwarz, Michael E Mullins
BACKGROUND: Cannabinoid hyperemesis syndrome (CHS) is characterized by symptoms of cyclic abdominal pain, nausea, and vomiting in the setting of prolonged cannabis use. The transient receptor potential vanilloid 1 (TRPV1) receptor may be involved in this syndrome. Topical capsaicin is a proposed treatment for CHS; it binds TRPV1 with high specificity, impairing substance P signaling in the area postrema and nucleus tractus solitarius via overstimulation of TRPV1. This may explain its apparent antiemetic effect in this syndrome...
May 11, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28489809/cannabis-induced-bullous-lung-disease-leading-to-pneumothorax-case-report-and-literature-review
#12
Rashmi Mishra, Ravi Patel, Misbahuddin Khaja
RATIONALE: Marijuana use has been increasing in the United States among college students and young adults. Marijuana use has been associated with bullous lung disease which can lead to pneumothorax. There are other recreational drugs like methylphenidate, cocaine and heroin which have been associated with pneumothorax. PATIENT CONCERNS: We present a case of a 30-year-old man with spontaneous pneumothorax associated with marijuana use. The patient had no medical conditions and presented to the emergency room with chest pain...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28485092/in-transition-culture-of-experimentation-with-cannabis-in-latin-american-college-students-a-new-role-within-a-potential-drug-use-sequencing-pattern
#13
João Mauricio Castaldelli-Maia, Sérgio Nicastri, Magdalena Cerdá, June H Kim, Lúcio Garcia de Oliveira, Arthur Guerra de Andrade, Silvia S Martins
INTRODUCTION AND AIMS: Given a scenario of intense discussion about the legal situation of cannabis users worldwide, this paper aims to investigate the role of cannabis within a drug use sequencing pattern. DESIGN AND METHODS: Data came from a representative sample of college students from 27 Brazilian capitals (n = 12 711). We analysed the patterns of transition from/to the first use of cannabis to/from the first use of alcohol, tobacco and seven other illegal drugs...
May 8, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28476279/medical-cannabis-use-among-patients-with-chronic-pain-in-an-interdisciplinary-pain-rehabilitation-program-characterization-and-treatment-outcomes
#14
Arya Shah, Julia Craner, Julie L Cunningham
INTRODUCTION: Cannabis is increasingly being used in the treatment of chronic pain. However, there is a lack of available research in the population of patients with chronic pain who are using cannabis. The current study examines clinical and treatment characteristics for patients who are admitted to a 3-week outpatient interdisciplinary chronic pain rehabilitation program. METHOD: Participants (N=48) included patients with a positive urine drug screen for 9-carboxy-tetrahydrocannabinol (THC(+); n=24) and a matched comparison sample of patients with a negative screen (THC(-); n=24)...
June 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28465661/primary-spontaneous-pneumothorax-admitted-in-emergency-unit-does-first-episode-differ-from-recurrence-a-cross-sectional-study
#15
S Kepka, J C Dalphin, A L Parmentier, J B Pretalli, M Gantelet, N Bernard, F Mauny, T Desmettre
Introduction. Management of primary spontaneous pneumothorax (PSP) consists of immediate resolution of pleural air, or observation, and prevention of recurrence. The risk factors for recurrence remain debated. Objectives. We aimed to describe and compare the characteristics of patients presenting a first episode of PSP to those of patients presenting a recurrent PSP, in order to identify factors potentially related to recurrence. Methods. We conducted a cross-sectional study including all admissions for PSP in the EDs of fourteen French public hospitals from 2009 to 2013...
2017: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/28458396/state-and-national-contexts-in-evaluating-cannabis-laws-a-case-study-of-washington-state
#16
Christopher Cambron, Katarina Guttmannova, Charles B Fleming
As of January 2016, 23 U.S. states and the District of Columbia have legalized medical or nonmedical cannabis, with more likely to follow. This dynamic policy context represents a substantial challenge for policy evaluation. Part I of this article provides a summary of state-level cannabis policy components across states and federal action regarding state-level policies. Part II presents a detailed history of cannabis policies in Washington State from 1998 to 2015 and analyzes the potential impacts of the policy changes on cannabis supply and demand...
January 2017: Journal of Drug Issues
https://www.readbyqxmd.com/read/28457767/clinical-and-financial-implications-of-emergency-department-visits-for-synthetic-marijuana
#17
Eric Rowley, David Benson, Aaron Tiffee, Adam Hockensmith, Henry Zeng, Glenn N Jones, Mandi W Musso
BACKGROUND: Many users believe that synthetic cannabinoids offer a safe and legal means of getting high. However, spikes in emergency department visits have been associated with use of synthetic cannabinoids. The purpose of the current study was to document emergency department visits from three large hospitals in one metropolitan area over a two month period. METHOD: This was a retrospective chart review examining 218 patients presenting to three inner city emergency departments between March and April 2014...
April 23, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28457058/cannabis-in-inflammatory-bowel-diseases-from-anecdotal-use-to-medicalization
#18
Timna Naftali, Fred M Konikoff
No abstract text is available yet for this article.
February 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28457054/efficacy-of-medical-cannabis-for-treatment-of-refractory-epilepsy-in-children-and-adolescents-with-emphasis-on-the-israeli-experience
#19
Moran Hausman-Kedem, Uri Kramer
No abstract text is available yet for this article.
February 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28456895/cannabis-use-medication-management-and-adherence-among-persons-living-with-hiv
#20
Denise C Vidot, Brenda Lerner, Raul Gonzalez
Cannabis is used to relieve nausea, trigger weight gain, and reduce pain among adults living with HIV; however, the relationship between its use and medication adherence and management is unclear. Participants (N = 107) were from an ongoing cohort study of community-dwelling HIV+ adults, stratified by cannabis (CB) use: HIV+/CB+ (n = 41) and HIV+/CB- (n = 66). CB+ participants either tested positive in a urine toxicology screen for THC or had a self-reported history of regular and recent use. HIV-status was provided by physician results and/or biomarker assessment...
April 29, 2017: AIDS and Behavior
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