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https://www.readbyqxmd.com/read/29776731/comorbidity-in-illness-induced-posttraumatic-stress-disorder-versus-posttraumatic-stress-disorder-due-to-external-events-in-a-nationally-representative-study
#1
Jordana L Sommer, Natalie Mota, Donald Edmondson, Renée El-Gabalawy
OBJECTIVE: The current study compared physical and mental health characteristics and quality of life of illness-induced posttraumatic stress disorder (PTSD) versus those with PTSD due to external traumatic events in a population-based sample. METHOD: PTSD was assessed with the Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS-5) using DSM-5 criteria in the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions. Participants with past-year PTSD (n = 1779) were categorized into two groups: illness-induced (6...
May 10, 2018: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29776705/-pneumothorax-in-young-cannabis-smokers-a-propos-of-three-cases
#2
M-L Chardon, J-C Dalphin, B Degano
INTRODUCTION: Cannabis consumption is common among adolescents and young adults in France. In addition to its neurological effect, cannabis smoking can induce severe pulmonary emphysema, even in young patients. When a spontaneous pneumothorax occurs in a cannabis smoker, the possibility of a secondary spontaneous pneumothorax should be considered. This may be of importance as management of secondary spontaneous pneumothorax may differ from the well-codified handling of primary spontaneous pneumothorax...
May 15, 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29776349/randomised-controlled-trial-rct-of-cannabinoid-replacement-therapy-nabiximols-for-the-management-of-treatment-resistant-cannabis-dependent-patients-a-study-protocol
#3
Anjali K Bhardwaj, David J Allsop, Jan Copeland, Iain S McGregor, Adrian Dunlop, Marian Shanahan, Raimondo Bruno, Nghi Phung, Mark Montebello, Craig Sadler, Jessica Gugusheff, Melissa Jackson, Jennifer Luksza, Nicholas Lintzeris
BACKGROUND: The cannabis extract nabiximols (Sativex®) effectively supresses withdrawal symptoms and cravings in treatment resistant cannabis dependent individuals, who have high relapse rates following conventional withdrawal treatments. This study examines the efficacy, safety and cost-effectiveness of longer-term nabiximols treatment for outpatient cannabis dependent patients who have not responded to previous conventional treatment approaches. METHODS/DESIGN: A phase III multi-site outpatient, randomised, double-blinded, placebo controlled parallel design, comparing a 12-week course of nabiximols to placebo, with follow up at 24 weeks after enrolment...
May 18, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29773016/is-cannabidiol-a-promising-substance-for-new-drug-development-a-review-of-its-potential-therapeutic-applications
#4
Nida Noreen, Faqir Muhammad, Bushra Akhtar, Farooq Azam, Muhammad Irfan Anwar
The pharmacological importance of cannabidiol (CBD) has been in study for several years. CBD is the major nonpsychoactive constituent of plant Cannabis sativa and its administration is associated with reduced side effects. Currently, CBD is undergoing a lot of research which suggests that it has no addictive effects, good safety profile and has exhibited powerful therapeutic potential in several vital areas. It has wide spectrum of action because it acts through endocannabinoid receptors; CB1 and CB2 and it also acts on other receptors, such as GPR18, GPR55, GPR 119, 5HT1A, and TRPV2...
2018: Critical Reviews in Eukaryotic Gene Expression
https://www.readbyqxmd.com/read/29770251/review-of-the-neurological-benefits-of-phytocannabinoids
#5
REVIEW
Joseph Maroon, Jeff Bost
Background: Numerous physical, psychological, and emotional benefits have been attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia. The phytocannabinoids, cannabidiol (CBD), and delta-9-tetrahydrocannabinol (Δ9-THC) are the most studied extracts from cannabis sativa subspecies hemp and marijuana. CBD and Δ9-THC interact uniquely with the endocannabinoid system (ECS). Through direct and indirect actions, intrinsic endocannabinoids and plant-based phytocannabinoids modulate and influence a variety of physiological systems influenced by the ECS...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29769496/substance-use-among-the-patients-with-first-episode-psychosis
#6
M S Ahsan, M S Mullick, K Begum, S M Arafat, M A Shah, B R Podder, J Roy
Substance Use Disorder is a frequent problem in Bangladesh and many of these patients develop psychosis. Substance use can cause psychosis and it can modify the course of psychosis. This cross-sectional study was done to see the proportion of substance use in patients with First-Episode Psychosis (FEP) in two tertiary care hospitals in Dhaka, Bangladesh mentioned here as Bangabandhu Sheikh Mujib Medical University and Dhaka Medical College Hospital; from November 2007 March 2009. Fifty consecutive FEP patients were taken as subjects and 50 healthy attendants were recruited as control...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29766748/medical-cannabis-for-pediatric-moderate-to-severe-complex-motor-disorders
#7
Stephanie Libzon, Lihi Bar-Lev Schleider, Naama Saban, Luda Levit, Yulia Tamari, Ilan Linder, Tally Lerman-Sagie, Lubov Blumkin
A complex motor disorder is a combination of various types of abnormal movements that are associated with impaired quality of life (QOL). Current therapeutic options are limited. We studied the efficacy, safety, and tolerability of medical cannabis in children with complex motor disorder. This pilot study was approved by the institutional ethics committee. Two products of cannabidiol (CBD) enriched 5% oil formulation of cannabis were compared: one with 0.25% δ-9-tetrahydrocannabinol (THC) 20:1 group, the other with 0...
January 1, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29761015/the-influence-of-thc-cbd-oromucosal-spray-on-driving-ability-in-patients-with-multiple-sclerosis-related-spasticity
#8
Elisabeth G Celius, Carlos Vila
Background: Driving ability is a key function for the majority of patients with multiple sclerosis (MS) to help maintain daily interactions. Both physical and cognitive disability, as well as treatments, may affect the ability to drive. Spasticity is a common symptom associated with MS, and it may affect driving performance either directly or via the medications used to treat it. In this article, we review the evidence relating the antispasticity medicine, Δ9 -tetrahydrocannabinol:cannabidiol (THC:CBD) oromucosal spray (Sativex® ), and its potential impact on driving performance...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29757806/medical-cannabis-for-the-treatment-of-fibromyalgia
#9
Francesco Crestani
No abstract text is available yet for this article.
May 11, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29752639/prevalence-of-hiv-viral-load-suppression-among-psychiatric-inpatients-with-comorbid-substance-use-disorders
#10
D M Coviello, R Lovato, K Apostol, M M Eisenberg, D S Metzger, R Szucs-Reed, N Kiryankova-Dalseth, D Kelly, A Jackson, M Plano, M B Blank
A consistently suppressed viral load enables HIV (+) patients to live longer, healthier lives and reduces the probability of transmitting the virus. Since the prevalence of HIV is four times higher among those with psychiatric disorders than in the general population, it is likely that this group would also have greater difficulty remaining in care and achieving viral suppression. A secondary data analysis utilizing screening data from the Preventing AIDS Through Health (PATH) for Triples (PFT) Study were examined to assess HIV load suppression among 254 psychiatric inpatients with comorbid substance use disorders in Philadelphia...
May 11, 2018: Community Mental Health Journal
https://www.readbyqxmd.com/read/29746420/decriminalization-of-drug-use
#11
Balasingam Vicknasingam, Suresh Narayanan, Darshan Singh, Marek Chawarski
PURPOSE OF REVIEW: To review the literature on decriminalization of drug use from 2016 to 2017 and suggest the way forward. RECENT FINDINGS: The systematic review of the literature on decriminalization resulted in seven articles that discuss decriminalization as compared with 57 published articles on legalization. Decriminalization of drug use did not have an effect on the age of onset of drug use and the prices of drugs did not decrease after the implementation of drug decriminalization...
May 8, 2018: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/29742676/recommendations-from-cannabis-dispensaries-about-first-trimester-cannabis-use
#12
Betsy Dickson, Chanel Mansfield, Maryam Guiahi, Amanda A Allshouse, Laura M Borgelt, Jeanelle Sheeder, Robert M Silver, Torri D Metz
OBJECTIVE: To characterize recommendations given to pregnant women by Colorado cannabis dispensaries regarding use of cannabis products for nausea during the first trimester of pregnancy. METHODS: This was a statewide cross-sectional study in which advice about cannabis product use was requested using a mystery caller approach. The caller stated she was 8 weeks pregnant and experiencing morning sickness. Dispensaries were randomly selected from the Colorado Department of Revenue Enforcement Division website...
May 7, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29738560/an-indirect-estimation-of-the-population-size-of-students-with-high-risk-behaviors-in-select-universities-of-medical-sciences-a-network-scale-up-study
#13
Homeira Sajjadi, Zahra Jorjoran Shushtari, Mohsen Shati, Yahya Salimi, Masoomeh Dejman, Meroe Vameghi, Salahedin Karimi, Zohreh Mahmoodi
BACKGROUND: Network scale-up is one of the most important indirect methods of estimating the size of clandestine populations and people with high-risk behaviors. The present study is an indirect estimation of the population size of students with high-risk behaviors in select universities of medical sciences. METHODS: A total of 801 students from two University of Medical Sciences at Tehran and Alborz University of Medical Sciences were selected through convenience sampling...
2018: PloS One
https://www.readbyqxmd.com/read/29735538/cma-position-against-separate-regulations-for-medical-cannabis-draws-ire-and-insults
#14
Brian Owens
No abstract text is available yet for this article.
May 7, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29724959/new-breath-related-topics-sample-collection-for-exhaled-breath-condensate-and-aerosol-development-of-real-time-medical-alerts-measurement-of-artificial-atmospheres-and-analysis-of-legalized-cannabis-product
#15
Joachim D Pleil, Ariel Wallace
Exhaled breath technology is expanding beyond conventional gas-phase analysis, and conversely, methodology from other disciplines is finding applications in breath research. Recently, the authors attended conferences that incorporated new technologies into "breath related" applications. The first was the International Submarine Air Monitoring and Air Purification (SAMAP) held in Uncasville Connecticut, November 2017, and the second was the Pittcon Conference and Exposition (Pittcon) held in Orlando Florida, February 2018...
May 4, 2018: Journal of Breath Research
https://www.readbyqxmd.com/read/29714640/cannabis-in-end-of-life-care-examining-attitudes-and-practices-of-palliative-care-providers
#16
Rachel Luba, Mitch Earleywine, Stacey Farmer, Melissa Slavin
Medical cannabis research has become quite extensive, with indications ranging from glaucoma to chemotherapy-induced nausea. Despite increased interest in cannabis' potential medical uses, research barriers, cannabis legislation, stigma, and lack of dissemination of data contribute to low adoption for some medical populations. Of interest, cannabis use appears low in palliative care settings, with few guidelines available to palliative care providers. The present study sought to examine the attitudes, beliefs, and practices of palliative care providers regarding the use of cannabis for terminally ill patients...
May 1, 2018: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/29709847/big-data-on-a-big-new-market-insights-from-washington-state-s-legal-cannabis-market
#17
Jonathan P Caulkins, Yilun Bao, Steve Davenport, Imane Fahli, Yutian Guo, Krista Kinnard, Mary Najewicz, Lauren Renaud, Beau Kilmer
INTRODUCTION: Voters in eight U.S. states have passed initiatives to legalize large-scale commercial production of cannabis for non-medical use. All plan or require some form of "seed-to-sale" tracking systems, which provide a view of cannabis market activity at a heretofore unimagined level of detail. Legal markets also create a range of new matters for policy makers to address. DATA: Publicly available data were obtained on approximately 45 million individually priced items purchased in the 35 million retail transactions that took place during the first two and a half years of Washington State's legal cannabis market...
April 27, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29699529/substance-use-and-suicidal-ideation-and-behaviour-in-low-and-middle-income-countries-a-systematic-review
#18
Elsie Breet, Daniel Goldstone, Jason Bantjes
BACKGROUND: Understanding relationships between substance use and suicidal ideation and behaviour (SIB) has important public health implications for suicide prevention in low- and middle-income countries (LMICs), where 75% of suicides occur. This systematic review explored the associations between substance use and SIB in LMICs. METHODS: We searched five databases using a combination of keywords for substance use, SIB and LMICs to identify English-written quantitative studies published between January 2006 and February 2016...
April 24, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29689485/the-effect-of-high-dose-dronabinol-oral-thc-maintenance-on-cannabis-self-administration
#19
Nicolas J Schlienz, Dustin C Lee, Maxine L Stitzer, Ryan Vandrey
BACKGROUND: There is a clear need for advancing the treatment of cannabis use disorders. Prior research has demonstrated that dronabinol (oral THC) can dose-dependently suppress cannabis withdrawal and reduce the acute effects of smoked cannabis. The present study was conducted to evaluate whether high-dose dronabinol could reduce cannabis self-administration among daily users. METHODS: Non-treatment seeking daily cannabis users (N = 13) completed a residential within-subjects crossover study and were administered placebo, low-dose dronabinol (120 mg/day; 40 mg tid), or high-dose dronabinol (180-240 mg/day; 60-80 mg tid) for 12 consecutive days (order counterbalanced)...
April 17, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29688777/frequency-of-cannabis-use-and-medical-cannabis-use-among-persons-living-with-hiv-in-the-united-states-findings-from-a-nationally-representative-sample
#20
Lauren R Pacek, Sheri L Towe, Andrea L Hobkirk, Denis Nash, Renee D Goodwin
Little is known about cannabis use frequency, medical cannabis use, or correlates of use among persons living with HIV (PLWH) in United States nationally representative samples. Data came from 626 PLWH from the 2005-2015 National Survey on Drug Use and Health. Logistic regression identified characteristics associated with frequency of cannabis use. Chi-squares identified characteristics associated with medial cannabis use. Non-daily and daily cannabis use was reported by 26.9% and 8.0%. Greater perceived risk of cannabis use was negatively associated with daily and non-daily use...
April 2018: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
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