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Claudio de Lucia, Markus Wallner, Deborah M Eaton, Huaqing Zhao, Steven R Houser, Walter J Koch
Heart disease is the leading cause of hospitalization and death worldwide, severely affecting health care costs. Aging is a significant risk factor for heart disease and the senescent heart is characterized by structural and functional changes including diastolic and systolic dysfunction as well as left ventricular (LV) dyssynchrony. Speckle-tracking based strain echocardiography (STE) has been shown as a non-invasive, reproducible and highly sensitive methodology to evaluate LV function in both animal models and humans...
June 18, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Ahmet Karakurt, Cennet Yildiz, Abdülmelik Yildiz, Yavuz Karabağ, Metin Çağdaş, İbrahim Rencüzoğulları, İnanç Artaç, Doğan İliş
OBJECTIVE: To evaluate left atrial (LA) deformation parameters strain (S)/strain rate (SR) and time to peak S/SR obtained by two-dimensional speckle tracking echocardiography (2D-STE) in patients with hypertension for three LA mechanical phases and to compare them with the same indices in the control subjects. METHODS: Fifty-five patients with hypertension (HT) and 29 healthy controls were included in the study. All patients had normal LA poster-anterior diameter, LA and left ventricular ejection fractions (LVEF >50%) in two-dimensional echocardiography (2-DE)...
June 18, 2018: Acta Cardiologica
Oana Mirea, Oana Maria Corîci, Mihaela Berceanu, Ionuţ Donoiu, Constantin Militaru, Octavian Istratoaie
Speckle tracking echocardiography offers a unique opportunity to evaluate myocardial function, and global longitudinal strain (GLS) is currently recommended as a measurement of global left ventricular function. To facilitate clinical applicability of the method, collective efforts have been made to standardise strain measurements and to raise awareness of the potential sources of variability. The purpose of this review is to familiarise the reader with the most common sources of variability of longitudinal strain measurements and detail the possible measures to increase the accuracy and reproducibility of strain parameters...
June 18, 2018: Acta Cardiologica
N M Sharath Babu, Sirish C Srinath, Anandaroop Lahiri, David Chase, Bobby John, John Roshan
Background and objectives: Right ventricular (RV) pacing can lead to progressive ventricular dysfunction over a certain period. This pacemaker-induced cardiomyopathy (PiCMP) may be more common than previously reported. Speckle tracking imaging is a recent development in echocardiography that can identify left ventricular (LV) dysfunction even before the LV ejection fraction (LVEF) value decreases. Three-dimensional (3D) echocardiography has made more accurate assessment of LVEF possible...
April 2018: Journal of the Saudi Heart Association
Lucia Wilke, Francisca E Abellan Schneyder, Markus Roskopf, Andreas C Jenke, Andreas Heusch, Kai O Hensel
Speckle tracking echocardiography (STE) is increasingly used during functional assessments. However, reproducibility and dependence on echocardiographic image quality for speckle tracking stress echocardiography in pediatric patients have not been studied to date. 127 consecutive normotensive children without structural heart disease (mean age 13.4 ± 3.0 years, 50.4% female) underwent a stepwise semisupine cycle ergometric protocol. Left ventricular (LV) myocardial peak strain and strain rate were assessed at rest and during exercise...
June 15, 2018: Scientific Reports
Cristina Cruz, Teresa Pinho, Carla Sousa, Cláudia Camila Dias, José Silva Cardoso, Maria Júlia Maciel
BACKGROUND: Late after tetralogy of Fallot (TOF) repair some patients exhibit aortic dilatation and stiffness. Noninvasive assessment of aortic stiffness could contribute to understand this aortopathy and may be important in risk stratification for major aortic event. METHODS: We included prospectively 82 adults after TOF repair and 41 age- and sex-matched normal controls. Aortic diameters were measured by two-dimensional transthoracic echocardiography and the aortic z-score was estimated...
June 13, 2018: Echocardiography
Ewa Pilichowska-Paszkiet, Jakub Baran, Grażyna Sygitowicz, Agnieszka Sikorska, Sebastian Stec, Piotr Kułakowski, Beata Zaborska
AIM: Left atrial (LA) fibrosis promotes atrial fibrillation (AF), may predict poor radiofrequency catheter ablation (RFCA) outcome, and may be assessed invasively using electroanatomical mapping (EAM). Speckle tracking echocardiography (STE) enables quantitative assessment of LA function. The aim was to assess the relationship between LA fibrosis derived from EAM and LA echocardiographic parameters as well as biomarkers of fibrosis in patients with AF. METHODS: Sixty-six patients (64% males, mean age 56 ± 10) with nonvalvular AF treated with first RFCA were prospectively studied...
June 13, 2018: Echocardiography
Antonio Vitarelli, Maria Teresa Petrucci, Silvia Lai, Carlo Gaudio, Lidia Capotosto, Enrico Mangieri, Serafino Ricci, Simone De Sio, Giovanni Truscelli, Federico Vozella, Mario Sergio Pergolini
The dataset presented in this article is related to the research article entitled "Biventricular assessment of light-chain amyloidosis using 3D speckle tracking echocardiography: Differentiation from other forms of myocardial hypertrophy" (Vitarelli et al., 2018) [1], which examined the potential utility of left ventricular (LV) and right ventricular (RV) deformation and rotational parameters derived from three-dimensional speckle-tracking echocardiography (3DSTE) to diagnose cardiac amyloidosis(CA) and differentiate this disease from other forms of myocardial hypertrophy...
June 2018: Data in Brief
Runlan Luo, Hongyan Cui, Dongmei Huang, Lihua Sun, Shengda Song, Mengyao Sun, Guangsen Li
BACKGROUND: Right ventricular function is a crucial factor of the prognosis of systemic lupus erythematosus (SLE). OBJECTIVES: To evaluate the right ventricular function in SLE patients with different degrees of pulmonary hypertension (PH) by strain and strain rate imaging. METHODS: A total of 102 SLE patients and 30 healthy volunteers were studied between October 2015 and May 2016. Patients were divided into three groups according to pulmonary artery systolic pressure (PASP) estimated by echocardiography: group control (A); PASP ≤ 30 mmHg (group B, n = 37); PASP 30-50 mmHg (mild PH; group C, n = 34); and PASP ≥ 50 mmHg (moderate-to-severe PH; group D, n = 31)...
June 11, 2018: Arquivos Brasileiros de Cardiologia
Nina Rolf, Laura Kerschke, Janina Braun, Maria Karina Falkenberg, Kerstin Hammer, Helen Ann Köster, Mareike Möllers, Kathrin Oelmeier de Murcia, Walter Klockenbusch, Ralf Schmitz
PURPOSE: The purpose of our study was to quantify the fetal myocardial function in pregnant women with diabetic diseases (FDM) and in normal controls (FC) using speckle tracking echocardiography (STE). METHODS: In this prospective study, the myocardial strain and dyssynchrony were analyzed using STE in a transversal four-chamber view in 180 fetuses (53 FDM, 127 FC) between 19 and 39 weeks of gestation. The measurements of the global and segmental longitudinal strain of both chambers (2C) and of the single left chamber (1C) were executed offline via QLab 10...
June 12, 2018: Journal of Perinatal Medicine
Hui-Min Hu, Xiao-Lin Zhang, Wei-Ling Zhang, Dong-Sheng Huang, Zhong-Dong Du
Background: Cardiotoxicity is one of the most serious chronic complications of anthracyclines therapy. Assessment of the left ventricular ejection fraction (LVEF) fails to detect subtle cardiac dysfunction of left ventricular (LV). This study aimed to detect and evaluate new parameters of subclinical anthracyclines' cardiotoxicity in children with solid tumor. Methods: A detailed echocardiographic examination was performed in 36 children with hepatoblastoma or rhabdomyosarcoma after receiving anthracyclines' chemotherapy and 36 healthy controls from January 2015 to December 2016...
June 20, 2018: Chinese Medical Journal
Masaaki Takeuchi, Victor Chien-Chia Wu
PURPOSE OF REVIEW: Myocardial strain imaging has gained popularity during the last decade in various clinical scenarios. The objective of this article was to review the potential application of two-dimensional (2D) and three-dimensional (3D) strains in patients with coronary artery disease. RECENT FINDINGS: Reports on the diagnostic accuracy of myocardial deformation analysis using 2D and 3D speckle-tracking analyses to detect significant coronary stenosis at rest or during stress and to evaluate myocardial viability are limited...
June 7, 2018: Current Opinion in Cardiology
Anub G John, Glenn A Hirsch, Marcus F Stoddard
OBJECTIVES: This study assessed if frequent premature atrial contractions (PACs) were associated with decreased left atrial (LA) strain and adverse remodeling. BACKGROUND: Left atrial dysfunction and enlargement increases risk of stroke. If frequent PACs cause LA dysfunction and remodeling, PAC suppressive therapy may be beneficial. METHODS: Inclusion criteria were age ≥18 years and sinus rhythm. Exclusion criteria were atrial fibrillation or any etiology for LA enlargement...
June 10, 2018: Echocardiography
Henning Johann Steffen, Sebastian Kalverkamp, Rashad Zayat, Rüdiger Autschbach, Jan-Wilhelm Spillner, Andreas Hagendorff, Nima Hatam
PURPOSE: To assess whether thoracic non-cardiac surgery has an influence on right ventricular function (RVF) compared to known impaired postoperative RV function after cardiac surgery. METHODS: In all, 50 patients (mean age: 61 years), who underwent thoracic non-cardiac surgery were included and matched using propensity score to 50 patients, receiving coronary artery bypass graft surgery (CABG) (CABGmatched ). All patients had transthoracic echocardiography (TTE) including two-dimensional speckle tracking (2D-STE) and tissue Doppler imaging (TDI) pre- and 1 week postoperatively...
June 7, 2018: Annals of Thoracic and Cardiovascular Surgery
Pierre-Emmanuel Séguéla, Julie Thomas-Chabaneix, Zakaria Jalal, François Roubertie, Léa Faydi, Jean-Baptiste Mouton, Eric Dumas-de-la-Roque, Olivier Tandonnet, Xavier Pillois, Jean-Benoit Thambo, Xavier Iriart
BACKGROUND: Coarctation of the aorta (CoA) is still challenging to diagnose in neonates with patent ductus arteriosus (PDA). Speckle tracking echocardiography allows reliable analysis of myocardial deformation in newborns and seems to provide important insides into regional changes in patients with left ventricular (LV) outflow tract obstruction. AIMS: To assess the interest of LV global longitudinal strain (GLS) measurement for predicting CoA in neonates with PDA and prenatal suspicion...
June 3, 2018: Archives of Cardiovascular Diseases
Erhan Saracoglu, Salih Kılıç, Ertan Vuruşkan, Irfan Düzen, Yusuf Çekici, Zülfiye Kuzu, Arafat Yıldırım, Mehmet Küçükosmanoğlu, Mustafa Çetin
BACKGROUND AND AIMS: Few studies have shown the direct effect of familial hypercholesterolemia (FH) on myocardial systolic function. Studies focused on heterozygote FH patients but not homozygote ones, and they did not perform genetic analyses. We aimed to evaluate all types of patients with FH using the potentially more sensitive speckle tracking echocardiography (STE) technique to identify early left ventricular (LV) dysfunction. METHODS: Genetic analyses of patients with FH were conducted for LDL-receptor, PCSK9, and ApoB100...
June 5, 2018: Echocardiography
D A Shveс, S V Povetkin
BACKGROUND: An important aspect of ischemic heart disease (IHD) diagnosis is the assessment of alterations of regional contractility (ARC) of the left ventricle. Speckle tracking imaging is a relatively new diagnostic method used for this purpose. Aim of this study was to identify optimal parameters of left ventricular (LV) deformation by speckle-tracking echocardiography which can differentiate quantitatively degrees of ARC of all left ventricular segments in patients with acute and chronic forms of IHD...
May 2018: Kardiologiia
Rachel N Lord, Victor Utomi, David L Oxborough, Bryony A Curry, Megan Brown, Keith P George
BACKGROUND: The cardiac consequences of undertaking endurance exercise are the topic of recent debate. The purpose of this review is to provide an update on a growing body of literature, focusing on left ventricular (LV) function following prolonged endurance exercise over 2 h in duration which have employed novel techniques, including myocardial speckle tracking, to provide a more comprehensive global and regional assessment of LV mechanics. METHODS: Prospective studies were filtered independently following a pre-set criteria, resulting in the inclusion of 27 studies in the analyses...
June 5, 2018: European Journal of Applied Physiology
Pieter van der Bijl, Victoria Delgado, Marianne Bootsma, Jeroen J Bax
The etiology of dilated cardiomyopathy (DCM) can be grouped as either genetic or nongenetic. More than 50 pathogenic genes have been described, with sarcomeric and lamin A/C mutations being the most common. Mutation carriers for genetic DCM are often asymptomatic until cardiac disease manifests with heart failure, arrhythmias, or sudden cardiac death. Preventive strategies are promising but can only be applied and tested adequately if genetic DCM can be diagnosed at an early stage. Early diagnosis of mutation carriers that may develop overt DCM requires advanced imaging techniques that can detect subtle structural and functional abnormalities...
June 5, 2018: Circulation
Veysel Tosun, Necmettin Korucuk, Ali Yaşar Kılınç, Turgut Uygun, Refik Emre Altekin, Ünal Güntekin, Cengiz Ermiş
OBJECTIVE: Nondippers are known to carry a high risk of cardiovascular morbidity and mortality. The aim of this study was to investigate the effects of dipper and nondipper status of hypertension on left atrial (LA) systolic and diastolic functions using two-dimensional speckle tracking echocardiography (2D-STE), P-wave dispersion (PWD), and P terminal force (PTF) in hypertensive patients. METHODS: A total of 72 patients and 39 healthy individuals were included in the study...
June 4, 2018: Echocardiography
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