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https://www.readbyqxmd.com/read/29457984/cardio-oncology-the-role-of-advanced-echocardiography-in-cancer-patients
#1
Lucia Venneri, Giacomo Zoppellaro, Rajdeep S Khattar
Cardio-oncology is a rapidly growing field aimed at improving the quality of care of cancer patients by preventing and monitoring cardiovascular complications resulting from cancer treatment. Cardiac imaging, and in particular, transthoracic echocardiography, plays an essential role in the baseline assessment and serial follow-up of cardio-oncology patients. Areas covered: This review article discusses the role of cardiac imaging with a focus on advanced echocardiography for the detection and management of cancer therapy related cardiovascular complications, in particular, left ventricular dysfunction and heart failure...
February 19, 2018: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/29457264/comparison-of-left-atrial-size-and-function-in-hypertrophic-cardiomyopathy-and-in-fabry-disease-with-left-ventricular-hypertrophy
#2
María Cristina Saccheri, Tomás Francisco Cianciulli, Wilde Challapa Licidio, Jorge A Lax, Martín A Beck, Luis A Morita, Juan A Gagliardi
BACKGROUND: Fabry disease (FD) and hypertrophic cardiomyopathy (HCM) are two diseases with a different pathophysiology, both cause left ventricular hypertrophy (LVH) and myocardial fibrosis. Although remodeling and systolic dysfunction of the left atrium (LA) are associated with atrial fibrillation and stroke in HCM, changes in the size and function of the LA have not been well studied in FD with LVH. METHODS: The following groups were studied prospectively, and their respective findings compared: 19 patients with non-obstructive HCM (Group I), 20 patients with a diagnosis of Fabry cardiomyopathy (Group II), and 20 normal subjects matched for sex and age (Group III)...
February 19, 2018: Echocardiography
https://www.readbyqxmd.com/read/29454478/usefulness-of-integrating-heart-failure-risk-factors-into-impairment-of-global-longitudinal-strain-to-predict-anthracycline-related-cardiac-dysfunction
#3
M Wesley Milks, Michael R Velez, Nishaki Mehta, Abiodun Ishola, Thomas Van Houten, Vedat O Yildiz, Raquel Reinbolt, Maryam Lustberg, Sakima A Smith, David A Orsinelli
The prediction of cancer therapeutics-related cardiac dysfunction (CTRCD) is an essential aspect of care for individuals who receive potentially cardiotoxic oncologic treatments. Certain clinical risk factors have been described for incident CTRCD, and measurement of left ventricular (LV) longitudinal strain by speckle tracking 2-dimensional echocardiography (2DE) is the best-validated myocardial mechanical imaging assessment to detect subtle changes in LV function during cancer treatment. However, the direct integration of clinical and imaging risk factors to predict CTRCD has not yet been extensively examined...
January 12, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29451950/intrinsic-changes-of-left-ventricular-function-in-patients-with-beh%C3%A3-et-disease-and-comparison-according-to-systemic-disease-activity
#4
Byung Joo Sun, Jae-Hyeong Park, Su-Jin Yoo, Yunseon Park, Yeon Ju Kim, In Suk Lee, Jinhyun Kim, In Seol Yoo, Seung Cheol Shim, Seong Wook Kang, Jun-Hyung Kim, Jae-Hwan Lee, Si Wan Choi, Jin-Ok Jeong, In-Whan Seong
PURPOSE: Although cardiac manifestation of Behçet disease (BD) has been described in sporadic reports, its timely diagnosis remains difficult. The objective of this study was to describe early cardiac manifestations of BD. We also performed a comprehensive classification of systemic BD activity and compared their cardiac manifestations. METHODS: A prospective screening using speckle tracking echocardiography was performed in 85 patients with BD who had no history of heart disease...
February 16, 2018: Echocardiography
https://www.readbyqxmd.com/read/29449957/early-detection-of-myocardial-dysfunction-using-two-dimensional-speckle-tracking-echocardiography-in-a-young-cat-with-hypertrophic-cardiomyopathy
#5
Ryohei Suzuki, Yohei Mochizuki, Hiroki Yoshimatsu, Ayaka Niina, Takahiro Teshima, Hirotaka Matsumoto, Hidekazu Koyama
Case summary: A 5-month-old intact female Scottish Fold cat was presented for cardiac evaluation. Careful auscultation detected a slight systolic murmur (Levine I/VI). The findings of electrocardiography, thoracic radiography, non-invasive blood pressure measurements and conventional echocardiographic studies were unremarkable. However, two-dimensional speckle tracking echocardiography revealed abnormalities in myocardial deformations, including decreased early-to-late diastolic strain rate ratios in longitudinal, radial and circumferential directions, and deteriorated segmental systolic longitudinal strain...
January 2018: JFMS Open Reports
https://www.readbyqxmd.com/read/29446126/layer-specific-global-longitudinal-strain-reveals-impaired-cardiac-function-in-patients-with-reversible-ischemia
#6
Christoffer E Hagemann, Søren Hoffmann, Flemming J Olsen, Peter G Jørgensen, Thomas Fritz-Hansen, Jan S Jensen, Tor Biering-Sørensen
AIMS: Two-dimensional speckle tracking echocardiography (2DSTE) detects early signs of left ventricular dysfunction; however, it is unknown whether layer-specific global longitudinal strain (GLS) has incremental value in diagnosis of patients with reversible ischemia assessed by single photon emission computed tomography (SPECT). METHODS AND RESULTS: Eighty patients with stable angina pectoris (SAP), normal left ventricular ejection fraction (LVEF), and no history of ischemic heart disease were retrospectively identified to have been examined by 2DSTE, SPECT, and coronary angiography (CAG)...
February 15, 2018: Echocardiography
https://www.readbyqxmd.com/read/29437242/impact-of-procedure-related-conduction-disturbances-after-transcatheter-aortic-valve-implantation-on-myocardial-performance-and-survival-evaluated-by-conventional-and-speckle-tracking-echocardiography
#7
Zisis Dimitriadis, Smita Scholtz, Werner Scholtz, Marcus Wiemer, Cornelia Piper, Stephan Ensminger, Henrik Fox, Dieter Horstkotte, Lothar Faber
OBJECTIVES: Although procedure-related new cardiac conduction disturbances (CCDs) remain an important issue in transcatheter aortic valve implantation (TAVI), their effect on myocardial function and overall patient outcome remains unclear. The goal of this study was to analyze the influence of procedure-related CCDs on systolic and diastolic LV performance and on patient survival after TAVI. METHODS AND RESULTS: Ninety-five patients who underwent TAVI for severe symptomatic aortic stenosis (AS) and had a complete follow-up were evaluated with respect to procedure-related CCDs...
February 13, 2018: Echocardiography
https://www.readbyqxmd.com/read/29436195/impact-of-ambulatory-blood-pressure-on-early-cardiac-and-renal-dysfunction-in-hypertensive-patients-without-clinically-apparent-target-organ-damage
#8
Darae Kim, Chi Young Shim, Geu Ru Hong, Sungha Park, In Jeong Cho, Hyuk Jae Chang, Jong Won Ha, Namsik Chung
PURPOSE: Impaired left ventricular (LV) global longitudinal strain (GLS) and the presence of microalbuminuria indicate early cardiac and renal dysfunction. We aimed to determine the relationships among 24-h ambulatory blood pressure (BP) variables, LV GLS, and urine albumin creatinine ratio (UACR) in hypertensive patients. MATERIALS AND METHODS: A total of 130 hypertensive patients (mean age 53 years; 59 men) underwent 24-h ambulatory BP monitoring, measurements of peripheral and central BPs, and transthoracic echocardiography...
March 2018: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29425560/right-atrial-function-in-patients-with-pulmonary-hypertension-a-study-with-two-dimensional-speckle-tracking-echocardiography
#9
Xiangli Meng, Yidan Li, Hong Li, Yidan Wang, Weiwei Zhu, Xiuzhang Lu
BACKGROUND: The role of right atrial (RA) dysfunction in patients with pulmonary hypertension (PH), as evaluated by two-dimensional speckle-tracking echocardiography (2D-STE) remains to be determined. METHODS: Sixty consecutive PH patients and 30 healthy volunteers were included. RA function was evaluated by 2D-STE, and the following parameters were recorded: an average longitudinal strain (LS) curve that included LSpos during RA filling and LSneg representing RA active contraction (their summation is LStot), the phasic RA volumes, total RA emptying fraction, and the ratio of RA passive and active emptying to total emptying...
March 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29423213/cardiovascular-effects-of-metabolic-syndrome-after-transplantation-convergence-of-obesity-and-transplant-related-factors
#10
Kristen Sgambat, Sarah Clauss, Asha Moudgil
Children are at increased risk of developing metabolic syndrome (MS) after kidney transplantation, which contributes to long-term cardiovascular (CV) morbidities and decline in allograft function. While MS in the general population occurs due to excess caloric intake and physical inactivity, additional chronic kidney disease and transplant-related factors contribute to the development of MS in transplant recipients. Despite its significant health consequences, the interplay of the individual components in CV morbidity in pediatric transplant recipients is not well understood...
February 2018: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29422386/multilayer-global-longitudinal-strain-in-patients-with-cancer-a-comparison-of-two-vendors
#11
Yann Ancedy, Stephane Ederhy, Sylvie Lang, Antoine Hollebecque, Laurie Soulat Dufour, Saroumadi Adavane-Scheuble, Arnaud Etienney, Marion Chauvet, Jean Charles Soria, Ariel Cohen
BACKGROUND: Global longitudinal strain (GLS) has several sources of variation. Strain multilayer tracking is a new tool that has not yet been validated in clinical practice. AIM: The purpose of this study was to investigate intervendor variability when measuring multilayer strain in patients receiving chemotherapy for cancer. METHODS: Patients receiving chemotherapy for cancer, who were referred for echocardiography, were included prospectively...
February 5, 2018: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29413646/assessment-of-left-ventricular-function-by-echocardiography-the-case-for-routinely-adding-global-longitudinal-strain-to-ejection-fraction
#12
REVIEW
Elizabeth Potter, Thomas H Marwick
Left ventricular (LV) ejection fraction (LVEF) is a simple measure of global systolic function that pervades the risk evaluation and management of many cardiovascular diseases. However, this parameter is limited not only by technical challenges, but also by pathophysiological entities where the ratio of stroke volume to LV cavity size is preserved. The assessment of global longitudinal strain (GLS) from speckle-tracking analysis of 2-dimensional echocardiography has become a clinically feasible alternative to LVEF for the measurement of myocardial function...
February 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29408823/torsion-mechanics-as-an-indicator-of-more-advanced-left-ventricular-systolic-dysfunction-in-secondary-mitral-regurgitation-in-patients-with-dilated-cardiomyopathy-a-2d-speckle-tracking-analysis
#13
Elena Kinova, Natalia Spasova, Angelina Borizanova, Assen Goudev
Left ventricular (LV) twist serves as a compensatory mechanism in systolic dysfunction and its degree of reduction may reflect a more advanced stage of disease. AIM: The aim was to investigate twist alterations depending on the degree of functional mitral regurgitation (MR) by speckle-tracking echocardiography. METHODS: Sixty-three patients with symptomatic dilated cardiomyopathy (DCM) were included. Patients were divided according to MR vena contracta width (VCW): group 1 with VCW <7 mm (mild/moderate MR) and group 2 with VCW ≥7 mm (severe MR)...
February 6, 2018: Cardiology
https://www.readbyqxmd.com/read/29408793/imaging-corneal-biomechanical-responses-to-ocular-pulse-using-high-frequency-ultrasound
#14
Elias Pavlatos, Hong Chen, Keyton Clayson, Xueliang Pan, Jun Liu
Imaging corneal biomechanical changes or abnormalities is important for better clinical diagnosis and treatment of corneal diseases. We propose a novel ultrasound-based method, called ocular pulse elastography (OPE), to image corneal deformation during the naturally occurring ocular pulse. Experiments on animal and human donor eyes, as well as synthetic radiofrequency (RF) data, were used to evaluate the efficacy of the OPE method. Using very high-frequency ultrasound (center frequency = 55 MHz), correlation-based speckle tracking yielded an accuracy of less than 10% error for axial tissue displacements of or above...
February 2018: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/29408714/effect-of-exercise-training-on-left-ventricular-mechanics-after-acute-myocardial-infarction-an-exploratory-study
#15
Gordon McGregor, Eric J Stöhr, David Oxborough, Peter Kimani, Rob Shave
BACKGROUND: cardiac rehabilitation (CR) exercise training is beneficial after myocardial infarction (MI). Whilst the peripheral adaptations to training are well defined, little is known regarding the effect on left ventricular (LV) remodelling, particularly LV function. Efficient LV ejection and filling is achieved through deformation and rotation of the myocardium in systole and diastole - LV mechanics. The response of LV mechanics to CR exercise training in MI patients is unknown. METHODS: in this observational exploratory study, 36 (of 40 enrolled) male, MI patients completed either 10-weeks of twice-weekly gym based cardiovascular exercise at 60-80% VO2peak (n=18), or a non-exercise control period (n=18)...
January 30, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29399871/the-correlation-between-cardiac-magnetic-resonance-t2-and-left-ventricular-global-longitudinal-strain-in-people-with-%C3%AE-thalassemia
#16
Mozhgan Parsaee, Nehzat Akiash, Azita Azarkeivan, Zahra Alizadeh Sani, Ahmad Amin, Mahboubeh Pazoki, Niloufar Samiei, Mohammad Ali Jalili, Mohammad Hassan Adel, Nahid Rezaian
BACKGROUND: Heart failure is the biggest cause of mortality and morbidity in people with thalassemia, and iron deposition in cardiac tissue impairs cardiovascular function. Therefore, early detection of cardiac involvement is important to improve the prognosis in these individuals. METHOD: Two- and three-dimensional echocardiography was performed to evaluate left ventricular ejection fraction (LVEF), left ventricular volumes and diameters, and global longitudinal strain (GLS) in 130 individuals with β-thalassemia using the speckle tracking method...
February 4, 2018: Echocardiography
https://www.readbyqxmd.com/read/29399870/assessment-of-myocardial-strain-in-children-with-risk-factors-for-atherosclerosis-with-use-of-3d-speckle-tracking-echocardiography
#17
Peixu Zhang, Dongqing Li, Yanzhuo Su, Xiaona Wang, Jianping Sun, Yang Xu, Jinghui Sun
BACKGROUND: The known risk factors for atherosclerosis such as dyslipidemia, hypertension, obesity, and fasting hyperglycemia are associated with subclinical myocardial dysfunction. We assessed myocardial strain in children who had risk factors for atherosclerosis with use of 3D speckle tracking echocardiography (3DSTE). METHODS: A total of 340 eligible children (mean age [±SD]: 9.5 [±1.9] years; range, 7.1-12.2; 189 males, 151 females). Levels of serum cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), fasting blood glucose (FBG), systolic blood pressure (SBP), diastolic blood pressure (DBP), and body mass index (BMI) were investigated...
February 4, 2018: Echocardiography
https://www.readbyqxmd.com/read/29399851/ultrasound-strain-imaging-to-assess-the-biceps-brachii-muscle-in-chronic-poststroke-spasticity
#18
Jing Gao, Johnson Chen, Michael O'Dell, Pai-Chi Li, Wen He, Li-Juan Du, Jonathan M Rubin, William Weitzel, Robert Min
OBJECTIVES: The aim of the study was to assess the feasibility of ultrasound strain imaging in characterizing the biceps brachii muscle in chronic poststroke spasticity. METHODS: We prospectively analyzed strain imaging data from bilateral biceps brachii muscles in 8 healthy volunteers and 7 patients with poststroke chronic spasticity. Axial deformations of the biceps brachii muscle and overlying subcutaneous tissue were produced by external compression using a sandbag (1...
February 5, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29399203/3d-characterization-of-corneal-deformation-using-ultrasound-speckle-tracking
#19
Keyton Clayson, Elias Pavlatos, Yanhui Ma, Jun Liu
The three-dimensional (3D) mechanical response of the cornea to intraocular pressure (IOP) elevation has not been previously reported. In this study, we use an ultrasound speckle tracking technique to measure the 3D displacements and strains within the central 5.5 mm of porcine corneas during the whole globe inflation. Inflation tests were performed on dextran-treated corneas (treated with a 10% dextran solution) and untreated corneas. The dextran-treated corneas showed an inflation response expected of a thin spherical shell, with through-thickness thinning and in-plane stretch, although the strain magnitudes exhibited a heterogeneous spatial distribution from the central to more peripheral cornea...
November 2017: Journal of Innovative Optical Health Sciences
https://www.readbyqxmd.com/read/29395940/two-dimensional-speckle-tracking-echocardiography-in-calves-feasibility-and-repeatability-study
#20
L Lecoq, N Moula, H Amory, F Rollin, A Leroux
OBJECTIVES: To assess the feasibility and repeatability of two-dimensional speckle tracking echocardiography for the evaluation of left ventricular function in healthy calves. ANIMALS: 12 Holstein calves, 62 ± 11.6 days old; 75.25 ± 5.4 Kg. METHODS: Observational study. Right parasternal short-axis views at papillary muscle level were recorded in standing calves and subsequently analyzed by two-dimensional speckle tracking for global and regional radial and circumferential strains and strain rates and radial displacement...
January 29, 2018: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
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