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"Cardiovascular magnetic resonance"

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https://www.readbyqxmd.com/read/29350784/novel-cardiovascular-magnetic-resonance-cmr-oxygenation-approaches-in-understanding-pathophysiology-of-cardiac-diseases
#1
Karthigesh Sree Raman, Gaetano Nucifora, Joseph B Selvanayagam
Cardiovascular Magnetic Resonance Imaging (CMR) permits accurate phenotyping of many cardiac diseases. CMR's inherent advantages are its non-invasive nature, lack of ionizing radiation and high accuracy and reproducibility. Furthermore, it is able to assess many aspects of cardiac anatomy, structure and function. Specifically, it can characterize myocardial tissue, myocardial function, myocardial mass, myocardial blood flow/perfusion, irreversible and reversible injury, all with a high degree of accuracy and reproducibility...
January 19, 2018: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29343710/phenotypic-diversity-identified-by-cardiac-magnetic-resonance-in-a-large-hypertrophic-cardiomyopathy-family-with-a-single-myh7-mutation
#2
Jie Wang, Ke Wan, Jiayu Sun, Weihao Li, Hong Liu, Yuchi Han, Yucheng Chen
Limited data is available on phenotypic variations with the same genotype in hypertrophic cardiomyopathy (HCM). The present study aims to explore the relationship between genotype and phenotype characterized by cardiovascular magnetic resonance (CMR) in a large Chinese family. A proband diagnosed with HCM from a multigenerational family underwent next-generation sequencing based on a custom sureSelect panel, including 117 candidate pathogenic genes associated with cardiomyopathies. All genetic results were confirmed by the Sanger sequencing method...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29334490/differential-impact-of-local-and-regional-aortic-stiffness-on-left-ventricular-remodeling-a-cardiovascular-magnetic-resonance-study
#3
Thiago Quinaglia, Mourad Z Bensalah, Emilie Bollache, Nadjia Kachenoura, Gilles Soulat, Pierre Boutouyrie, Stéphane Laurent, Elie Mousseaux
BACKGROUND: Left ventricular (LV) remodeling and aortic stiffness have independent predictive value for all causes and cardiovascular mortality. Because elastic properties of the arterial wall vary along the aortic pathway, we hypothesized that local and regional aortic stiffness could differently impact on LV remodeling. METHODS AND RESULTS: Regional aortic stiffness was determined from carotid-femoral pulse wave velocity (cfPWV) measured by aplanation tonometry...
January 13, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29332606/tricuspid-flow-and-regurgitation-in-congenital-heart-disease-and-pulmonary-hypertension-comparison-of-4d-flow-cardiovascular-magnetic-resonance-and-echocardiography
#4
Mieke M P Driessen, Marjolijn A Schings, Gertjan Tj Sieswerda, Pieter A Doevendans, Erik H Hulzebos, Marco C Post, Repke J Snijder, Jos J M Westenberg, Arie P J van Dijk, Folkert J Meijboom, Tim Leiner
BACKGROUND: Tricuspid valve (TV) regurgitation (TR) is a common complication of pulmonary hypertension and right-sided congenital heart disease, associated with increased morbidity and mortality. Estimation of TR severity by echocardiography and conventional cardiovasvular magnetic resonance (CMR) is not well validated and has high variability. 4D velocity-encoded (4D-flow) CMR was used to measure tricuspid flow in patients with complex right ventricular (RV) geometry and varying degrees of TR...
January 15, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29327119/nocturnal-hypoxemic-burden-is-associated-with-epicardial-fat-volume-in-patients-with-acute-myocardial-infarction
#5
Dominik Linz, Stefan Colling, Wolfgang Nußstein, Kurt Debl, Mathias Hohl, Claudia Fellner, Michael Böhm, Lars S Maier, Okka W Hamer, Stefan Buchner, Michael Arzt
BACKGROUND: Increased epicardial fat volume (EFV) is a common feature of patients with sleep-disordered breathing (SDB), is considered as an established marker of cardiovascular risk, and is associated with adverse cardiovascular events after myocardial infarction (MI). METHODS: To investigate the association between different measures of SDB severity and EFV after acute MI, we enrolled 105 patients with acute MI in this study. Unattended in-hospital polysomnography was performed to determine the number of apneas and hypopneas per hour during sleep (apnea-hypopnea index, AHI)...
January 11, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29321034/diagnostic-and-prognostic-utility-of-cardiovascular-magnetic-resonance-imaging-in-heart-failure-with-preserved-ejection-fraction-implications-for-clinical-trials
#6
Prathap Kanagala, Adrian S H Cheng, Anvesha Singh, John McAdam, Anna-Marie Marsh, Jayanth R Arnold, Iain B Squire, Leong L Ng, Gerry P McCann
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a poorly characterized condition. We aimed to phenotype patients with HFpEF using multiparametric stress cardiovascular magnetic resonance imaging (CMR) and to assess the relationship to clinical outcomes. METHODS: One hundred and fifty four patients (51% male, mean age 72 ± 10 years) with a diagnosis of HFpEF underwent transthoracic echocardiography and CMR during a single study visit. The CMR protocol comprised cine, stress/rest perfusion and late gadolinium enhancement imaging on a 3T scanner...
January 11, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29320864/diagnostic-performance-of-static-single-scan-stress-perfusion-cardiac-computed-tomography-in-detecting-hemodynamically-significant-coronary-artery-stenosis-a-comparison-with-combined-invasive-coronary-angiography-and-cardiovascular-magnetic-resonance-myocardial
#7
Inyoung Song, Jeong Geun Yi, Jeong Hee Park, Mi Young Kim, Je Kyoun Shin, Sung Min Ko
Background Non-invasive anatomical and physiological evaluations of coronary artery disease (CAD) may be obtained with static single-scan stress perfusion cardiac computed tomography (SSPCT). Purpose To determine the diagnostic performance of static SSPCT for identifying hemodynamically significant CAD. Material and Methods This prospective study included 29 patients with suspected or known CAD who underwent static SSPCT, cardiovascular magnetic resonance myocardial perfusion imaging (CMR-MPI), and invasive coronary angiography (ICA)...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29319785/diagnostic-accuracy-and-prognostic-value-of-simultaneous-hybrid-18f-fluorodeoxyglucose-positron-emission-tomography-magnetic-resonance-imaging-in-cardiac-sarcoidosis
#8
Eleanor C Wicks, Leon J Menezes, Anna Barnes, Saidi A Mohiddin, Neha Sekhri, Joanna C Porter, Helen L Booth, Emily Garrett, Riyaz S Patel, Menelaos Pavlou, Ashley M Groves, Perry M Elliott
Aims: Cardiac death is the leading cause of mortality in patients with sarcoidosis, yet cardiac involvement often remains undetected. Cardiovascular magnetic resonance imaging (CMR) and 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) have been used to diagnose cardiac sarcoidosis (CS) yet never simultaneously in a cohort. This study sought to assess the diagnostic and prognostic utility of simultaneous hybrid cardiac PET/MR. Methods and results: Fifty-one consecutive patients with suspected CS (age 50 ± 13 years, 31 males) underwent simultaneous PET/MR following a high-fat/low-carbohydrate diet and 12-h fast...
January 8, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29313213/effects-of-hyperaemia-on-left-ventricular-longitudinal-strain-in-patients-with-suspected-coronary-artery-disease-a%C3%A2-first-pass-stress-perfusion-cardiovascular-magnetic-resonance-imaging-study
#9
P Garg, R Aziz, T Al Musa, D P Ripley, P Haaf, J R J Foley, P P Swoboda, G J Fent, L E Dobson, J P Greenwood, S Plein
AIMS: Myocardial perfusion imaging during hyperaemic stress is commonly used to detect coronary artery disease. The aim of this study was to investigate the relationship between left ventricular global longitudinal strain (GLS), strain rate (GLSR), myocardial early (E') and late diastolic velocities (A') with adenosine stress first-pass perfusion cardiovascular magnetic resonance (CMR) imaging. METHODS AND RESULTS: 44 patients met the inclusion criteria and underwent CMR imaging...
January 8, 2018: Netherlands Heart Journal
https://www.readbyqxmd.com/read/29309572/cardiovascular-magnetic-resonance-imaging-in-hypertrophic-cardiomyopathy-the-importance-of-clinical-context
#10
Giovanni Quarta, Giovanni Donato Aquaro, Patrizia Pedrotti, Gianluca Pontone, Santo Dellegrottaglie, Attilio Iacovoni, Paolo Brambilla, Silvia Pradella, Giancarlo Todiere, Fausto Rigo, Chiara Bucciarelli-Ducci, Giuseppe Limongelli, Alberto Roghi, Iacopo Olivotto
In patients with suspected or established hypertrophic cardiomyopathy (HCM), cardiovascular magnetic resonance (CMR) is widely employed for clinical management, given its multimodality approach capable of providing unique information on cardiac morphology, function, and tissue characterization. Guidance regarding all aspects of HCM diagnosis and management is provided by the comprehensive 2014 European Society of Cardiology (ESC) guidelines on HCM. CMR should be performed in centres with recognized expertise in heart muscle diseases, by physicians who are familiar with the whole HCM disease spectrum, differential diagnoses, and pitfalls...
December 22, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29303369/quantification-of-the-left-atrium-applying-cardiovascular-magnetic-resonance-in-clinical-routine
#11
Stephanie Funk, Josephine Kermer, Serkan Doganguezel, Carsten Schwenke, Florian von Knobelsdorff-Brenkenhoff, Jeanette Schulz-Menger
OBJECTIVES: In recent years the impact of the left atrium (LA) has become more evident in different cardiovascular pathologies. We aim to provide LA parameters in healthy volunteers for cardiovascular magnetic resonance (CMR) using a fast approach. DESIGN: We analyzed 203 healthy volunteers (mean age 44.6 years (y), range 19y-76y) at 1.5 and 3.0 Tesla (T) using steady-state free precession (SSFP) cine in routine long axis view. Left atrial enddiastolic volume (LA-EDV), endsystolic volume (LA-ESV), stroke volume (LA-SV) and ejection fraction (LA-EF) were quantified and indexed to body-surface-area (BSA)...
January 5, 2018: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/29302945/a-new-method-to-evaluate-atrial-hemodynamic-and-quantify-mitral-regurgitation-using-cardiovascular-magnetic-resonance-the-pulmonary-venous-flow-approach
#12
Giovanni Benfari, Giulia Vinco, Karl Sayegh, Matthias Friedrich, Andrea Rossi
Pulmonary venous flow (PVF) provides incremental information on left ventricular (LV) diastolic function, and can support the diagnosis of severe mitral regurgitation (MR). The suggestion has been made to combine the left atrial filling volume (LA Fill) and PVF for estimating the mitral regurgitant volume, but echocardiographic PVF evaluation is known to have many limitations. The present case report includes an example of how to assess PVF using cardiovascular magnetic resonance, and a new method is proposed for quantification of the mitral regurgitant volume...
July 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29301584/correction-to-diagnostic-performance-of-semi-quantitative-and-quantitative-stress-cmr-perfusion-analysis-a-meta-analysis
#13
(no author information available yet)
In the original publication of this article there was an error in Figures 8, 9, 10 and 11. During typesetting the Figures 8, 9, 10 and 11 have been incorrectly swapped. In this "publisher correction" the correct and the incorrect figures are published. The original publication has been updated. BioMed central apologizes to the authors and readers for any inconvenience caused.
January 4, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29301529/increased-myocardial-extracellular-volume-assessed-by-cardiovascular-magnetic-resonance-t1-mapping-and-its-determinants-in-type-2-diabetes-mellitus-patients-with-normal-myocardial-systolic-strain
#14
Yukun Cao, Wenjuan Zeng, Yue Cui, Xiangchuang Kong, Miao Wang, Jie Yu, Shan Zhang, Jing Song, Xu Yan, Andreas Greiser, Heshui Shi
BACKGROUND: Cardiac magnetic resonance (CMR) T1 mapping and tissue-tracking strain analysis are useful quantitative techniques that can characterize myocardial tissue and mechanical alterations, respectively, in patients with early diabetic cardiomyopathy. The purpose of this study was to assess the left ventricular myocardial T1 value, extracellular volume fraction (ECV), and systolic strain in asymptomatic patients with type 2 diabetes mellitus (T2DM) and their underlying relationships with clinical parameters...
January 4, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29298704/the-prognostic-value-of-t1-mapping-and-late-gadolinium-enhancement-cardiovascular-magnetic-resonance-imaging-in-patients-with-light-chain-amyloidosis
#15
Lu Lin, Xiao Li, Jun Feng, Kai-Ni Shen, Zhuang Tian, Jian Sun, Yue-Ying Mao, Jian Cao, Zheng-Yu Jin, Jian Li, Joseph B Selvanayagam, Yi-Ning Wang
BACKGROUND: Cardiac impairment is associated with high morbidity and mortality in immunoglobulin light chain (AL) type amyloidosis, for which early identification and risk stratification is vital. For myocardial tissue characterization, late gadolinium enhancement (LGE) is a classic and most commonly performed cardiovascular magnetic resonance (CMR) parameter. T1 mapping with native T1 and extracellular volume (ECV) are recently developed quantitative parameters. We aimed to investigate the prognostic value of native T1, ECV and LGE in patients with AL amyloidosis...
January 3, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29298692/an-in-vivo-comparison-of-stimulated-echo-and-motion-compensated-spin-echo-sequences-for-3%C3%A2-t-diffusion-tensor-cardiovascular-magnetic-resonance-at-multiple-cardiac-phases
#16
Andrew D Scott, Sonia Nielles-Vallespin, Pedro F Ferreira, Zohya Khalique, Peter D Gatehouse, Philip Kilner, Dudley J Pennell, David N Firmin
BACKGROUND: Stimulated-echo (STEAM) and, more recently, motion-compensated spin-echo (M2-SE) techniques have been used for in-vivo diffusion tensor cardiovascular magnetic resonance (DT-CMR) assessment of cardiac microstructure. The two techniques differ in the length scales of diffusion interrogated, their signal-to-noise ratio efficiency and sensitivity to both motion and strain. Previous comparisons of the techniques have used high performance gradients at 1.5 T in a single cardiac phase...
January 3, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29290484/pulsed-wave-doppler-recordings-in-the-proximal-descending-aorta-in-patients-with-chronic-aortic-regurgitation-insights-from-cardiovascular-magnetic-resonance
#17
Odd Bech-Hanssen, Christian L Polte, Frida Svensson, Åse A Johnsson, Kerstin M Lagerstrand, Ulf Cederbom, Sinsia A Gao
BACKGROUND: The pulsed-wave Doppler recording in the descending aorta (PWDDAO) is one of the parameters used in grading aortic regurgitation (AR) severity. The aim of the present study was to investigate the assessment of chronic AR by PWDDAO with insights from cardiovascular magnetic resonance (CMR). METHODS: This prospective study comprised 40 patients investigated with echocardiography and CMR within 4 hours either prior to valve surgery (n = 23) or as part of their follow-up (n = 17) due to moderate or severe AR...
December 29, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29288037/simulation-based-quantification-of-native-t1-and-t2-of-the-myocardium-using-a-modified-molli-scheme-and-the-importance-of-magnetization-transfer
#18
Christos G Xanthis, Sebastian Bidhult, Andreas Greiser, Kelvin Chow, Richard B Thompson, Håkan Arheden, Anthony H Aletras
Quantitative cardiovascular Magnetic Resonance Imaging techniques are gaining wide acceptance within the MR community due to their potential to diagnose non-localized disease, guide therapy and improve patient outcome. During the last decade, there has been an increasing interest for developing new techniques that allow for simultaneous quantification of both T1 and T2 maps of myocardium. Newer studies demonstrated that the incorporation of MRI simulations could yield similar results to conventional mapping techniques in the myocardium...
December 26, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29288017/improved-lung-perfusion-after-left-pulmonary-artery-patch-enlargement-during-the-norwood-operation
#19
Mona Salehi Ravesh, Jens Scheewe, Tim Attmann, Abdullah Al Bulushi, Marka-Jill Jussli-Melchers, Michael Jerosch-Herold, Dominik D Gabbert, Philip Wegner, Hans-Heiner Kramer, Carsten Rickers
BACKGROUND: Optimal pulmonary perfusion is crucial for a well-functioning Fontan circulation in patients with hypoplastic left heart syndrome (HLHS). To obtain an adequate size of the left pulmonary artery (LPA), patch enlargement is a routine part of Hemi-Fontan procedure in our center. However, LPA patch enlargement at the time of the modified Norwood procedure may have surgical advantages. Therefore, the aim of this study was to evaluate if anatomical and functional effects of the new approach are superior...
December 26, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29287129/new-advances-in-fetal-cardiovascular-magnetic-resonance-imaging-for-quantifying-the-distribution-of-blood-flow-and-oxygen-transport-potential-applications-in-fetal-cardiovascular-disease-diagnosis-and-therapy
#20
REVIEW
Liqun Sun, Christopher K Macgowan, Sharon Portnoy, John G Sled, Shi-Joon Yoo, Lars Grosse-Wortmann, Edgar Jaeggi, John Kingdom, Mike Seed
Until recently, our modern understanding of fetal circulatory physiology has been largely based on invasive measurements made in fetal sheep. However, new MRI technology developed by our group has provided equivalent information about the distribution of blood flow and oxygen transport noninvasively. The initial findings largely confirm prior estimates about the human fetal circulation extrapolated from fetal sheep data and human ultrasound data. Here we describe the hemodynamics of the normal late gestation human fetal circulation by MRI and speculate about what the advent of this technology might mean in terms of the management of fetuses affected by placental insufficiency and congenital heart disease...
December 2017: Echocardiography
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