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Ozone therapy

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https://www.readbyqxmd.com/read/28403346/the-effects-of-ozone-on-bacterial-growth-and-thiol-disulphide-homeostasis-in-vascular-graft-infection-caused-by-mrsa-in-rats
#1
Barcin Ozturk, Tunay Kurtoglu, Selim Durmaz, Leyla Didem Kozaci, Filiz Abacigil, Bulent Ertugrul, Ozcan Erel
Purpose: To investigate the microbiological, inflammatory and oxidant effects of adjuvant ozone administration in experimental rat vascular graft infection model which has not been previously investigated. Methods: Forty adult Wistar rats were divided into Sham, Control, Vancomycin, Ozone, Vancomycin+Ozone groups. Grafts were inoculated with Methicillin-resistant Staphylococcus aureus (MRSA) strain and implanted subcutaneously. Rats were treated intraperitoneally with ozone and /or intramuscularly with vancomycin for 10 days...
March 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28376500/suppression-of-retinal-neovascularization-by-anti-ccr3-treatment-in-an-oxygen-induced-retinopathy-model-in-mice
#2
Shuichiro Hirahara, Miho Nozaki, Masaharu Ohbayashi, Norio Hasegawa, Daisuke Ozone, Yuichiro Ogura
PURPOSE: To investigate the association between retinal neovascularization and the CC chemokine receptor-3 (CCR3) in a mouse model of oxygen-induced retinopathy (OIR). METHODS: An OIR model in C57BL/6J mice was used as a retinal neovascularization model. An enzyme-linked immunosorbent assay was performed to evaluate the chronological change in vascular endothelial growth factor A (VEGF-A) and eotaxin expressions. CCR3 and VEGF subtype expression in the retina was examined using real-time RT-PCR, and CCR3, eotaxin, VEGF-A, and CD31 expression was examined immunohistochemically...
April 5, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28366866/the-effect-of-ozone-on-the-expression-of-metallothionein-in-tissues-of-rats-chronically-exposed-to-cadmium
#3
Halina Milnerowicz, Mariola Śliwińska-Mossoń, Krzysztof A Sobiech
Our aims were to evaluate the expression of metallothionein (MT) in an experimental rat model which experienced chronic exposure to cadmium (Cd) and to measure its expression after ozone therapy (OT) or oxygen (Ox) in the same model, as compared to the control group, which was exposed to neither cadmium nor ozone. Forty male Wistar rats were divided into 5 groups: control, Cd, Cd and Ox, Cd and Oz, and Oz. During our research, Cd concentration (ASA) and MT concentration (ELISA) were determined in supernatants of the kidneys, liver and pancreas...
March 18, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28352340/clinical-efficacy-of-lumbar-interbody-fusion-using-a-channel-system-combined-with-ozone-therapy-for-the-treatment-of-central-type-l3-l4-lumbar-disc-herniation
#4
Yu Wang, Hong Sun, Shuzhen Qin
The clinical efficacy of minimally invasive lumbar interbody fusion via the intervertebral foramen combined with ozone (O3) therapy for the treatment of L3-L4 central-type lumbar disc herniation was explored. We recruited patients with sciatica who attended our hospital between July 2013 and October 2015 and underwent lumbar X-ray (anteroposterior and lateral view), lumbar flexion-extension radiographs, computed tomography, and magnetic resonance imaging after admission. Seventy-four patients with central-type lumbar disc herniation but no other complications were randomly selected and divided into the observation and control groups...
February 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28349902/ozone-gas-effect-on-mineral-content-of-dentin-exposed-to-streptococcus-mutans-biofilm-an-energy-dispersive-x-ray-evaluation
#5
Rafaella M Chaves, Carlos Estrela, Paula C Cardoso, Terezinha de Je Barata, João B de Souza, Érica M de Torres, Cyntia Ra Estrela, Ana Pr Magalhães, Lawrence G Lopes
AIM: This study aims to assess the effect of ozone gas on dentin exposed to Streptococcus mutans biofilm by evaluation of mineral content [log calcium-to-phosphorus (Ca/P)] using energy-dispersive X-ray (EDX) spectroscopy. MATERIALS AND METHODS: Five human third molars were sectioned into four slices of dentin and distributed in four groups: I - control (no treatment); II - ozone therapy; III - biofilm development; IV - ozone therapy followed by biofilm development...
April 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28349063/thermography-improves-clinical-assessment-in-patients-with-systemic-sclerosis-treated-with-ozone-therapy
#6
Danuta Nowicka
Objective. Treatment of scleroderma is challenging and limited. The aim of our study was to evaluate the usefulness of thermography in assessment of the clinical condition (joints movability and skin thickness) in clinically advanced patients with systemic sclerosis before and after ozone therapy. Method. The study included 42 patients aged 32 to 73 years with advanced systemic sclerosis hospitalized in the university clinic between 2003 and 2006. Thermography and clinical examinations were conducted at baseline and after two series of bath in water with ozone...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28301687/effect-of-high-frequency-bio-oxidative-ozone-therapy-for-masticatory-muscle-pain-a-double-blind-randomised-clinical-trial
#7
T Celakil, A Muric, B Gokcen Roehlig, G Evlioglu, H Keskin
To evaluate the effect of bio-oxidative ozone application at the points of greatest pain in patients with chronic masticatory muscle pain. A total number of 40 (40 women, with a mean age of 31·7) were selected after the diagnosis of myofacial pain dysfunction syndrome according to the Research Diagnostic Criteria for temporomandibular disorder (RDC/TMD). The patients were randomly divided into two groups: patients received the ozone therapy at the point of greatest pain, ozone group (OG; n = 20); patients received the sham ozone therapy at the point of greatest pain, placebo group (PG; n = 20)...
March 16, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28261890/ozone-prevents-cochlear-damage-from-ischemia-reperfusion-injury-in-guinea-pigs
#8
Merih Onal, Cagdas Elsurer, Nebil Selimoglu, Mustafa Yilmaz, Ender Erdogan, Jale Bengi Celik, Oznur Kal, Ozkan Onal
The cochlea is an end organ, which is metabolically dependent on a nutrient and oxygen supply to maintain its normal physiological function. Cochlear ischemia and reperfusion (IR) injury is considered one of the most important causes of human idiopathic sudden sensorineural hearing loss. The aim of the present study was to study the efficacy of ozone therapy against cochlear damage caused by IR injury and to investigate the potential clinical use of this treatment for sudden deafness. Twenty-eight guinea pigs were randomized into four groups...
March 5, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28228618/preventive-effect-of-intravesical-ozone-supplementation-on-n-methyl-n-nitrosourea-induced-non-muscle-invasive-bladder-cancer-in-male-rats
#9
Kerem Teke, Tayyar A Ozkan, Oguz O Cebeci, Hasan Yilmaz, Muhammed E Keles, Levend Ozkan, Meltem O Dillioglugil, Demir K Yildiz, Ozdal Dillioglugil
Although non-muscle invasive bladder cancer (NMIBC) is widely seen in men, most laboratory studies of new intravesical therapies to prevent NMIBC have been conducted on female animals. In addition, ozone (O3) has been shown to be a beneficial agent as an intravesical application in the treatment of various disorders. In the current study, we evaluated the immunohistopathological oxidative-antioxidative effects of intravesical O3 treatment on n-methyl-n-nitrosourea (MNU)-induced NMIBC. Male Wistar-Albino rats (n=51) were divided into four groups: sham (n=6), O3 only (n=15), MNU only (n=15), and MNU+O3 (n=15)...
February 22, 2017: Experimental Animals
https://www.readbyqxmd.com/read/28216927/intraprostatic-ozone-therapy-a-minimally-invasive-approach-in-benign-prostatic-hyperplasia
#10
Shabbir Hussain, Deepti B Sharma, Fanindra S Solanki, Ajay Pathak, Dhananjay Sharma
INTRODUCTION: Transurethral resection of prostate (TURP) remains the golden standard therapy since decades. There are various minimally invasive therapies (MITs) for the treatment of benign prostatic hyperplasia (BPH). Still, there is a need for therapy with lesser side effects and better outcome. We had studied the effect of intraprostatic ozone injection (IPOI) as an MIT for patients with BPH who have failed trial without catheter (TWOC). MATERIALS AND METHODS: Thirty elderly patients with BPH with a prostate size of 30 g or more were enrolled for the study...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28179287/possible-therapeutic-effects-of-ozone-mixture-on-hypoxia-in-tumor-development
#11
REVIEW
Margherita Luongo, Anna Lisa Brigida, Luigi Mascolo, Gennaro Gaudino
Recent literature highlights that ozone therapy could be considered a viable adjuvant therapy in oncological patients receiving radio-chemotherapy. The use of ozone therapy in these patients enhances the action of chemotherapy and at the same time reduces side-effects, such as nausea, vomiting, opportunistic infections, buccal ulcers, hair loss and fatigue. Such positive therapeutic effects of ozone therapy can cause a larger physical and mental wellbeing resulting in improved quality of life. This work reviews the recent acquisition of scientific knowledge regarding the ozone therapy and highlights the molecular and cellular pathways involved...
2017: Anticancer Research
https://www.readbyqxmd.com/read/28169044/in%C3%A2-vitro-evaluation-of-wound-healing-and-antimicrobial-potential-of-ozone-therapy
#12
Gabriel Álvares Borges, Silvia Taveira Elias, Sandra Márcia Mazutti da Silva, Pérola Oliveira Magalhães, Sergio Bruzadelli Macedo, Ana Paula Dias Ribeiro, Eliete Neves Silva Guerra
Although ozone therapy is extensively applied when wound repair and antimicrobial effect are necessary, little is known about cellular mechanisms regarding this process. Thus, this study aimed to evaluate ozone cytotoxicity in fibroblasts (L929) and keratinocytes (HaCaT) cell lines, its effects on cell migration and its antimicrobial activity. Cells were treated with ozonated phosphate-buffered saline (8, 4, 2, 1, 0.5 and 0.25 μg/mL ozone), chlorhexidine 0.2% or buffered-solution, and cell viability was determined through MTT assay...
March 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28112142/transient-cortical-blindness-after-intradiscal-oxygen-ozone-therapy
#13
Agostino Salvatore Vaiano, Cristiana Valente, Giacomo De Benedetti, Guido Caramello
A 54-year-old caucasian male developed bilateral blindness during an oxygen-ozone injection for disc herniation. The visual loss (VL) was immediately followed by severe frontal headache, vomiting, and nausea. The patient underestimated the VL showing Anton's syndrome, with a complete visual recovery after 2-month follow-up. Magnetic resonance data were consistent with recent ischemic lesions in bilateral vascular territories of posterior cerebral arteries.
December 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28097518/beneficial-effects-of-ozone-therapy-on-oxidative-stress-cardiac-functions-and-clinical-findings-in-patients-with-heart-failure-reduced-ejection-fraction
#14
Mutlu Buyuklu, Fatih Mehmet Kandemir, Turan Set, Eftal Murat Bakırcı, Husnu Degirmenci, Hikmet Hamur, Ergun Topal, Sefa Kucukler, Kultigin Turkmen
The aim of study was to determine the effects of ozone therapy on the oxidative stress, cardiac functions and clinical findings in patients with heart failure reduced ejection fraction (HFrEF). A total of 40 patients with New York Heart Association 2 and 3 HF with left ventricular ejection fraction (LVEF) <35%, and 40 subjects without HF as control group were included in the study. Patients with HFrEF were given additional ozone therapy of major and minor administrations along with conventional HF treatment for 5 weeks...
January 17, 2017: Cardiovascular Toxicology
https://www.readbyqxmd.com/read/28076466/ozone-therapy-as-an-adjuvant-for-endondontic-protocols-microbiological-ex-vivo-study-and-citotoxicity-analyses
#15
Carlos Goes Nogales, Marina Beloti Ferreira, Antonio Fernando Montemor, Maria Filomena de Andrade Rodrigues, José Luiz Lage-Marques, João Humberto Antoniazzi
Objectives: This study evaluated the antimicrobial efficacy of ozone therapy in teeth contaminated with Pseudomonas aeruginosa, Enterococcus faecalis, and Staphylococcus aureus using a mono-species biofilm model. Parallel to this, the study aimed to evaluate the cytotoxicity of ozone for human gingival fibroblasts. Material and Methods: One hundred and eighty single-root teeth were contaminated with a mono-species biofilm of Enterococcus faecalis, Pseudomonas aeruginosa, and Staphylococcus aureus...
November 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28038382/the-nlrp3-inflammasome-is-a-potential-target-of-ozone-therapy-aiming-to-ease-chronic-renal-inflammation-in-chronic-kidney-disease
#16
Gang Yu, Zhiming Bai, Zhiyuan Chen, Hui Chen, Guoren Wang, Gang Wang, Zhenxiang Liu
Ozone therapy is an effective medical treatment for various diseases. A previous study has demonstrated its reno-protective effect in chronic kidney disease (CKD), but the mechanism involved is not completely known. This study produced the 5/6 nephrectomized CKD rat model and investigated whether the reno-protective effect of ozone therapy was achieved by its anti-inflammatory property through the modulation of the NLRP3 inflammasome. The results showed that ozone therapy at a low concentration improved renal function and ameliorated renal morphological injury in 5/6 nephrectomized rats...
February 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/27982260/effect-of-ozone-and-methylprednisolone-treatment-following-crush-type-sciatic-nerve-injury
#17
Omur Ozturk, Aysu Hayriye Tezcan, Yasemen Adali, Can Hakan Yıldırım, Ozgur Aksoy, Hatice Yagmurdur, Ali Bilge
PURPOSE: To assess and compare the histopathological effects of ozone therapy and/or methylprednisolone (MPS) treatment on regeneration after crush type sciatic nerve injury. METHODS: Forty Sprague-Dawley male rats were randomly allocated into four groups. Four groups received the following regimens intraperitoneally every day for 14 days after formation of crush type injury on sciatic nerve: Group I: ozone (20mcg/ml); Group II: methylprednisolone (2mg/kg); Group III: ozone (20 mcg/ml) and methylprednisolone (2mg/kg); Group IV: isotonic saline (0...
November 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27974724/myocardial-infarction-after-ozone-therapy-is-ozone-therapy-dr-jekyll-or-mr-hyde
#18
Çağın Mustafa Üreyen, Cem Yunus Baş, Şakir Arslan
No abstract text is available yet for this article.
2017: Cardiology
https://www.readbyqxmd.com/read/27918221/neutrophilic-inflammation-in-asthma-mechanisms-and-therapeutic-considerations
#19
Hun Soo Chang, Tae-Hyeong Lee, Ji Ae Jun, Ae Rin Baek, Jong-Sook Park, So-My Koo, Yang-Ki Kim, Ho Sung Lee, Choon-Sik Park
Neutrophilic airway inflammation represents a pathologically distinct form of asthma and frequently appears in symptomatic adulthood asthmatics. However, clinical impacts and mechanisms of the neutrophilic inflammation have not been thoroughly evaluated up to date. Areas covered: Currently, distinct clinical manifestations, triggers, and molecular mechanisms of the neutrophilic inflammation (namely Toll-like receptor, Th1, Th17, inflammasome) are under investigation in asthma. Furthermore, possible role of the neutrophilic inflammation is being investigated in respect to the airway remodeling...
January 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/27894109/ozone-therapy-and-its-use-in-medicine-further-comments
#20
Lamberto Re, Robert Rowen, Valter Travagli
No abstract text is available yet for this article.
2017: Cardiology
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