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Perthes disease

M Henze, H Alfonso, L Flicker, J George, S A Paul Chubb, G J Hankey, O P Almeida, J Golledge, P E Norman, B B Yeap
AIMS: To investigate behavioural, physical and biochemical characteristics associated with diabetes in the oldest age group of elderly men. METHODS: We conducted a cross-sectional analysis of community-dwelling men aged 79-97 years from Perth, Western Australia. Lifestyle behaviours, self-rated health, physical function, and fasting glucose and HbA1c levels were assessed. RESULTS: Of 1426 men, 315 had diabetes (22%). Men with diabetes were of similar age to men without (84...
October 20, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
Sherif Galal
: Developmental coxa vara (DCV) develops during early childhood between the age of independent walking and 6 years. The deformity includes a decrease in the neck-shaft angle and femoral retroversion. Recently, good results have been reported using external fixator systems for the correction of proximal femoral deformities secondary to slipped capital femoral epiphysis, Perthes' disease in children, and percutaneous proximal femoral osteotomy for coxa vara. This preliminary study was performed to evaluate the results of percutaneous subtrochanteric osteotomy in restoring the normal alignment and orientation (radiographic outcome), thereby restoring the normal mechanics of the hip joint, overcoming shortening of the limb, and re-establishing the length-tension relationship of the abductor muscles (functional outcome)...
September 29, 2016: Journal of Pediatric Orthopedics. Part B
U Lenoir, T Slongo, E Aghayev, A Joeris
Background: Transient synovitis is the most common hip joint disorder in children. Perthes disease occurs around the same age and may not be distinguishable to an episode of transient synovitis in the early stage. Therefore all children in our clinic with transient synovitis underwent a follow-up X-ray 3 months later to detect Perthes disease at an early stage. The aim of the study was to evaluate, if a follow-up X-ray is necessary for all children with suspected transient synovitis or if the clinical follow-up can lead to the indication for a follow-up X-ray...
October 12, 2016: Klinische Pädiatrie
Heather L Baltzer, Scott Riester, Steven L Moran
Background: The etiology of multifocal osteonecrosis is not definitively known; however, hypercoagulable state is a very plausible cause. Methods: We present an unusual case of a 12-year-old boy with a history of Legg-Calve-Perthes disease presenting with right wrist pain who was subsequently diagnosed with Kienbock's disease. The finding of multifocal osteonecrosis prompted testing for a hypercoagulable state that was positive for Factor V Leiden thrombophilia. A thorough literature review using Medline database was conducted to investigate associations between inherited hypercoagulable states and multifocal osteonecrosis...
September 2016: Hand: Official Journal of the American Association for Hand Surgery
Ran Schwarzkopf, Garwin Chin, Kelvin Kim, Dermot Murphy, Antonia F Chen
BACKGROUND: The incidence of hip fractures is growing with the increasing elderly population. Typically, hip fractures are treated with open reduction internal fixation, hemiarthroplasty, or total hip arthroplasty (THA). Failed hip fracture fixation is often salvaged by conversion THA. The total number of conversion THA procedures is also supplemented by its use in treating different failed surgical hip treatments such as acetabular fracture fixation, Perthes disease, slipped capital femoral epiphysis, and developmental dysplasia of the hip...
September 1, 2016: Journal of Arthroplasty
Sarah J Hardcastle, Rachael Glassey, Stuart Salfinger, Jason Tan, Paul Cohen
BACKGROUND: The study purpose was to investigate endometrial cancer survivors' health perceptions following cessation of active cancer treatment and to explore factors influencing participation in health-promoting behaviors. METHODS: Face-to-face interviews were conducted with participants who had completed active treatment of cancer within the previous 3 years. Participants were 22 endometrial cancer survivors (mean age = 62.55 years, SD = 7.08) at risk of cardiovascular disease who were recruited from 2 oncologists in Perth, Western Australia...
September 25, 2016: Psycho-oncology
Naga Suresh Adapala, Ryosuke Yamaguchi, Matthew Phipps, Olumide Aruwajoye, Harry K W Kim
In children with Legg-Calvé-Perthes disease, loss of blood supply to the femoral head results in ischemic osteonecrosis. Generally, macrophages play important roles in the inflammatory response to tissue necrosis, but their role in ischemic osteonecrosis of the femoral head (ONFH) is not known. The purpose of this study was to determine the macrophage-inflammatory responses after ONFH and the receptor mechanisms involved in sensing the necrotic bone, using a piglet model of Legg-Calvé-Perthes disease. Induction of ONFH resulted in increased numbers of CD14(+) macrophages (4...
September 17, 2016: American Journal of Pathology
Eduardo N Novais, Stephen Duncan, Jeffrey Nepple, Gail Pashos, Perry L Schoenecker, John C Clohisy
BACKGROUND: The goal of periacetabular osteotomy (PAO) is to improve the insufficient coverage of the femoral head and achieve joint stability without creating secondary femoroacetabular impingement. However, the complex tridimensional morphology of the dysplastic acetabulum presents a challenge to restoration of normal radiographic parameters. Accurate acetabular correction is important to achieve long-term function and pain improvement. There are limited data about the proportion of patients who have normal radiographic parameters restored after PAO and the factors associated with under- and overcorrection...
September 19, 2016: Clinical Orthopaedics and related Research
C Druschel, K Heck, C Kraft, R Placzek
OBJECTIVE: PemberSal osteotomy to improve femoral head coverage by rotating the acetabular roof ventrally and laterally. INDICATIONS: Insufficient coverage of the femoral head, and can be combined with other surgical procedures such as femoral intertrochanteric varus-derotation osteotomy and open reduction for developmental dysplasia and dislocation of the hip or to improve sphericity and containment in Legg-Calvé-Perthes disease. This specific acetabuloplasty can only be performed in patients with an open epiphyseal growth-plate...
September 14, 2016: Operative Orthopädie und Traumatologie
Takashi Yoshida, Wook-Cheol Kim, Atsushi Nishida, Yoshinobu Oka, Toshiharu Shirai, Kazuya Ikoma, Keiichiro Ueshima, Hiroyoshi Fujiwara, Toshikazu Kubo
OBJECTIVE: This study aimed to assess acetabular anteversion angle (AAA) from the early stage of Perthes disease to adolescence. METHODS: Twenty-five patients treated conservatively were examined. Changes in AAA from initial to final measurement were compared between the two groups (G-group: Stulberg classes I and II; P-group: classes III and IV). RESULTS: In the G-group, AAA decreased significantly in the affected hip compared with the unaffected hip, whereas AAA decreased in both hips in the P-group...
December 2016: Journal of Orthopaedics
James D Wylie, Jeremy A Ross, Jill A Erickson, Mike B Anderson, Christopher L Peters
BACKGROUND: Intraoperative fluoroscopy is commonly used to both guide the osteotomy and judge correction of the acetabular fragment in periacetabular osteotomy (PAO). Prior studies that have compared intraoperative fluoroscopic correction with postoperative radiographic correction were small studies that did not report intra- or interreader reliability. QUESTIONS/PURPOSES: (1) What is the correlation between intraoperative fluoroscopic correction in PAO compared with the correction seen on postoperative radiographs? (2) What is the reliability of radiographic measures of correction in PAO? METHODS: We performed a retrospective study of 121 patients (141 hips) who underwent PAO for symptomatic hip dysplasia at a tertiary referral center...
September 12, 2016: Clinical Orthopaedics and related Research
Torsten Johansson, Maria Lindblad, Marie Bladh, Ann Josefsson, Gunilla Sydsjö
Background and purpose - The incidence of Perthes' disease as reported in the literature varies widely between and within countries. The etiology of the disease is still unknown. Both environmental and genetic factors have been suggested to play a part in either causing the disease or increasing the susceptibility of an individual. We determined the incidence of Perthes' disease in Sweden and investigated possible relationships to parental socioeconomic status, ethnicity, marital status, mothers' age when giving birth, parity, number of siblings, and smoking habits...
September 2, 2016: Acta Orthopaedica
Markus S Hanke, Simon D Steppacher, Helen Anwander, Stefan Werlen, Klaus A Siebenrock, Moritz Tannast
BACKGROUND: Magnetic resonance arthrogram (MRA) with radial cuts is presently the best available preoperative imaging study to evaluate chondrolabral lesions in the setting of femoroacetabular impingement (FAI). Existing followup studies for surgical treatment of FAI have evaluated predictors of treatment failure based on preoperative clinical examination, intraoperative findings, and conventional radiography. However, to our knowledge, no study has examined whether any preoperative findings on MRA images might be associated with failure of surgical treatment of FAI in the long term...
August 31, 2016: Clinical Orthopaedics and related Research
Soong Joon Lee, Jeong Joon Yoo, Hee Joong Kim
BACKGROUND: Total hip arthroplasty (THA) for sequelae of Legg-Calve-Perthes disease (LCPD) involves specific concerns for deformity, leg length discrepancy (LLD), and relatively young age. Excellent long-term outcome has been proven after Alumina-Alumina (Al-Al) THA for relatively young patients, however, there was no study for Al-Al THA for LCPD sequelae. The aim of this study is to evaluate the results of Al-Al THA for LCPD sequelae and to compare the results with those for adult-onset ONFH, in which THA is necessitated in relatively young age and excellent long term outcome has been proven after Al-Al THA...
August 10, 2016: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
K Yao, J M Troupis
Diffusion-weighted imaging (DWI) is a magnetic resonance imaging (MRI) sequence that has a well-established role in neuroimaging, and is increasingly being utilised in other clinical contexts, including the assessment of various skeletal disorders. It utilises the variability of Brownian motion of water molecules; the differing patterns of water molecular diffusion in various biological tissues help determine the contrast obtained in DWI. Although early research on the clinical role of DWI focused mainly on the field of neuroimaging, there are now more studies demonstrating the promising role DWI has in the diagnosis and monitoring of various osseous diseases...
November 2016: Clinical Radiology
Talal Ibrahim, David G Little
No abstract text is available yet for this article.
July 19, 2016: JBJS Rev
Noam Shohat, Leonel Copeliovitch, Yossi Smorgick, Ran Atzmon, Yigal Mirovsky, Nogah Shabshin, Yiftah Beer, Gabriel Agar
BACKGROUND: Varus derotational osteotomy (VDRO) is one of the most common surgical treatments for Legg-Calvé-Perthes disease, yet its long-term results have not been fully assessed. We aimed to determine the long-term clinical and radiographic outcomes following VDRO. METHODS: Forty patients (43 hips) who underwent VDRO for Legg-Calvé-Perthes disease at our institution from 1959 to 1983, and participated in a follow-up study completed 10 years earlier, were approached for the present study...
August 3, 2016: Journal of Bone and Joint Surgery. American Volume
Tadahiko Ohtsuru, Yasuaki Murata, Yuji Morita, Yutaro Munakata, Yoshiharu Kato
Transient synovitis (TS) of the hip develops spontaneously in childhood; it usually has a good prognosis and is a self-limiting disease. However, its pathology is not well known. We describe a case of Legg-Calvé-Perthes disease (LCPD) that seemingly developed due to TS. Even if TS is diagnosed on the basis of the patient's medical history and imaging findings, physicians should consider the possibility of LCPD and perform a careful observation if joint effusion continues and/or a symptom does not improve within 4 weeks...
2016: Case Reports in Orthopedics
David Charles Neal, Travis Hall Alford, Amanda Moualeu, Chan-Hee Jo, John Anthony Herring, Harry K W Kim
INTRODUCTION: Children with Legg-Calvé-Perthes disease classically have been described as thin, small, and socioeconomically disadvantaged. Despite the obesity epidemic, no study has determined the prevalence of obesity in this patient population and its effect on treatment. METHODS: This is a retrospective study of 150 patients (172 hips) with Legg-Calvé-Perthes disease seen between 2009 and 2014. Patients were grouped based on body mass index at the initial visit...
September 2016: Journal of the American Academy of Orthopaedic Surgeons
Samantha C Burnham, Pierrick Bourgeat, Vincent Doré, Greg Savage, Belinda Brown, Simon Laws, Paul Maruff, Olivier Salvado, David Ames, Ralph N Martins, Colin L Masters, Christopher C Rowe, Victor L Villemagne
BACKGROUND: Brain amyloid β (Aβ) deposition and neurodegeneration have been documented in about 50-60% of cognitively healthy elderly individuals (aged 60 years or older). The long-term cognitive consequences of the presence of Alzheimer's disease pathology and neurodegeneration, and whether they have an independent or synergistic effect on cognition, are unclear. We aimed to characterise the long-term clinical and cognitive trajectories of healthy elderly individuals using a two-marker (Alzheimer's disease pathology and neurodegeneration) imaging construct...
September 2016: Lancet Neurology
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