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Perthes disease

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https://www.readbyqxmd.com/read/27920812/evaluation-of-the-bone-mineral-density-of-the-subjects-with-avascular-necrosis-of-hip-joint
#1
Mohammad Taghi Karimi, Seyed Mohammad Mousavi Nodoshan
BACKGROUND: The head of femur is deformed in subjects with Leg Calve Perthes Disease (LCPD). It may be due to an increase in loads applied on the hip, decrease in hip joint containment and decrease in bone mineral density (BMD) of femur. Unfortunately there is not enough evidence regarding BMD of femur in subjects with LCPD. Therefore, the aim of this study is to evaluate BMD in subjects with Perthes disease. METHOD: Two subjects with LCPD participated in this study...
May 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/27904729/treatment-of-late-onset-legg-calve-perthes-disease-by-arthrodiastasis
#2
Sung Soo Kim, Chan Woo Lee, Hyeon Jun Kim, Hyun Ho Kim, Lih Wang
BACKGROUND: To evaluate the efficacy of arthrodiastasis for Legg-Calve-Perthes disease. METHODS: Arthrodiastasis was conducted using external fixator devices (Orthofix) in 7 patients at least 8 years of age with a diagnosis of Legg-Calve-Perthes disease. The average follow-up was 80 months (range, 32 to 149 months), and their average age was 9.1 years (range, 8 to 12 years). The results of treatment were evaluated by measuring the degree of hip pain and the range of motion of the hip at 6 months after the operation and comparing the values with preoperative measurements...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27886352/alterations-of-serum-osteocalcin-levels-in-patients-with-legg-calv%C3%A3-perthes
#3
Wen-Bo Wei, Sha-Jie Dang, Yong Li, Zong-Zhi Liu
BACKGROUND: Legg-Calvé-Perthes disease (LCPD) is a paediatric form of osteonecrosis that ultimately heals but will cause femoral head and acetabular deformities. The purpose of this study was to investigate the early serum measurement of osteocalcin in children with femoral head necrosis compared with that of healthy children. METHODS: 20 patients with LCPD (4 girls and 16 boys) and 20 healthy volunteers (5 girls and 15 boys) were enrolled. All patients did not have additional treatment...
November 14, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27864891/3d-mri-quantification-of-femoral-head-deformity-in-legg-calv%C3%A3-perthes-disease
#4
Karen D Standefer, Molly Dempsey, ChanHee Jo, Harry K W Kim
The purpose of this study was to quantify femoral head deformity in patients with Legg-Calvé-Perthes disease (LCPD) using a novel three dimensional (3D) magnetic resonance imaging (MRI) reconstruction and volume based analysis. Bilateral femoral heads of 17 patients (mean age 9.9 ± 2.0 years; 12 boys, 5 girls) with LCPD were scanned 1-2 times (n= 33 LCPD heads, 20 normal heads) using a 1.5T MRI scanner. Fourteen patients had unilateral and three had bilateral LCPD with 5 hips in the Waldenström initial stage, 9 in the fragmentation stage, 14 in the reossification stage, and 5 in the healed stage...
November 19, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27852919/can-we-solve-legg-calv%C3%A3-perthes-disease-with-better-imaging-technology-commentary-on-an-article-by-harry-k-w-kim-md-ms-et-al-assessment-of-femoral-head-revascularization-in-legg-calv%C3%A3-perthes-disease-using-serial-perfusion-mri
#5
https://www.readbyqxmd.com/read/27852906/assessment-of-femoral-head-revascularization-in-legg-calv%C3%A3-perthes-disease-using-serial-perfusion-mri
#6
Harry K W Kim, Jamie Burgess, Alec Thoveson, Paul Gudmundsson, Molly Dempsey, Chan-Hee Jo
BACKGROUND: Legg-Calvé-Perthes disease is a juvenile form of osteonecrosis of the femoral head. The purpose of this study was to use serial perfusion magnetic resonance imaging (MRI) to determine the pattern and rate of revascularization of the femoral heads of patients with the active stage of Legg-Calvé-Perthes disease. METHODS: We performed a prospective study of 29 patients (30 hips) with a mean age (and standard deviation) of 8.4 ± 1.9 years who were diagnosed with Waldenström Stage-1 or 2 Legg-Calvé-Perthes disease...
November 16, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27832014/proximal-femoral-osteotomy-in-legg-calv%C3%A3-perthes-disease-using-a-monolateral-external-fixator-surgical-technique-outcome-and-complications
#7
Kwang-Won Park, Ishani P Shah, Ashok K Ramanathan, Tae-Jin Lee, Hae-Ryong Song
: Although external fixation methods have been described for proximal femoral osteotomy for various etiologies, none are dedicated to a single disease entity. Our study introduces a technique of proximal femoral osteotomy and fixation with a monolateral external fixator system in Legg-Calvé-Perthes disease (LCPD). Twenty-three patients (19 males, four females) with LCPD underwent surgery at our institute between 2004 and 2012. Varus osteotomy (group A, 11 hips) and valgus osteotomy (group B, 12 hips) were performed and the monolateral external fixator system was used...
November 9, 2016: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/27828982/discovery-and-partial-genomic-characterisation-of-a-novel-nidovirus-associated-with-respiratory-disease-in-wild-shingleback-lizards-tiliqua-rugosa
#8
Mark A O'Dea, Bethany Jackson, Carol Jackson, Pally Xavier, Kristin Warren
A respiratory disease syndrome has been observed in large numbers of wild shingleback lizards (Tiliqua rugosa) admitted to wildlife care facilities in the Perth metropolitan region of Western Australia. Mortality rates are reportedly high without supportive treatment and care. Here we used next generation sequencing techniques to screen affected and unaffected individuals admitted to Kanyana Wildlife Rehabilitation Centre in Perth between April and December 2015, with the resultant discovery of a novel nidovirus significantly associated with cases of respiratory disease according to a case definition based on clinical signs...
2016: PloS One
https://www.readbyqxmd.com/read/27828848/lateral-shelf-acetabuloplasty-for-severe-legg-calv%C3%A3-perthes-disease-in-patients-older-than-8-years-a-mean-eleven-year-follow-up
#9
Wen-Chao Li, Rui-Jiang Xu
The natural history of Legg-Calvé-Perthes disease (LCPD) in children older than 8 years is usually poor without treatment. The treatment goal is to prevent deformity and incongruity of the hip by achieving a stable spherical femoral head in a deep, congruent, sharp-edged acetabulum, with a good range of hip movement at skeletal maturity. Lateral shelf acetabuloplasty in LCPD can increase the coverage of the femoral head, benefiting the remodeling of the femoral head and acetabulum. The aim of this study was to evaluate the efficacy of lateral shelf acetabuloplasty for severe LCPD in patients older than 8 years...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27824790/intermediate-to-long-term-results-of-femoral-neck-lengthening-morscher-osteotomy
#10
Mark Eidelman, Doron Keshet, Scott Nelson, Noam Bor
BACKGROUND: Femoral neck lengthening and transfer of the greater trochanter were introduced by Morscher as treatment for patients with coxa breva and overgrowth of the greater trochanter. In this study we evaluated intermediate and long-term results of this operation. METHODS: We reviewed clinical and radiographic results of 18 patients (20 hips) who were treated by Morscher osteotomy. Ten patients had Perthes disease, 4 had developmental dysplasia of the hip, and 4 had avascular necrosis of the hip...
November 7, 2016: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/27761946/profile-of-diabetes-in-men-aged-79-97-years-the-western-australian-health-in-men-study
#11
M Henze, H Alfonso, L Flicker, J George, S A P Chubb, G J Hankey, O P Almeida, J Golledge, P E Norman, B B Yeap
AIMS: To investigate behavioural, physical and biochemical characteristics associated with diabetes in the oldest age group of elderly men. METHODS: We conducted a cross-sectional analysis of community-dwelling men aged 79-97 years from Perth, Western Australia. Lifestyle behaviours, self-rated health, physical function, and fasting glucose and HbA1c levels were assessed. RESULTS: Of 1426 men, 315 had diabetes (22%). Men with diabetes were of similar age to men without (84...
October 20, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27748677/percutaneous-multiplanar-subtrochanteric-osteotomy-with-external-fixation-for-developmental-coxa-vara-preliminary-results
#12
Sherif Galal
: Developmental coxa vara (DCV) develops during early childhood between the age of independent walking and 6 years. The deformity includes a decrease in the neck-shaft angle and femoral retroversion. Recently, good results have been reported using external fixator systems for the correction of proximal femoral deformities secondary to slipped capital femoral epiphysis, Perthes' disease in children, and percutaneous proximal femoral osteotomy for coxa vara. This preliminary study was performed to evaluate the results of percutaneous subtrochanteric osteotomy in restoring the normal alignment and orientation (radiographic outcome), thereby restoring the normal mechanics of the hip joint, overcoming shortening of the limb, and re-establishing the length-tension relationship of the abductor muscles (functional outcome)...
September 29, 2016: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/27733000/-the-value-of-conventional-radiographs-of-the-pelvis-in-detection-of-perthes-disease-3-months-after-an-episode-of-acute-transient-synovitis
#13
U Lenoir, T Slongo, E Aghayev, A Joeris
Background: Transient synovitis is the most common hip joint disorder in children. Perthes disease occurs around the same age and may not be distinguishable to an episode of transient synovitis in the early stage. Therefore all children in our clinic with transient synovitis underwent a follow-up X-ray 3 months later to detect Perthes disease at an early stage. The aim of the study was to evaluate, if a follow-up X-ray is necessary for all children with suspected transient synovitis or if the clinical follow-up can lead to the indication for a follow-up X-ray...
October 12, 2016: Klinische Pädiatrie
https://www.readbyqxmd.com/read/27698645/bilateral-legg-calve-perthes-disease-and-kienbock-s-disease-in-a-child-with-factor-v-leiden-thrombophilia-a-case-report
#14
Heather L Baltzer, Scott Riester, Steven L Moran
Background: The etiology of multifocal osteonecrosis is not definitively known; however, hypercoagulable state is a very plausible cause. Methods: We present an unusual case of a 12-year-old boy with a history of Legg-Calve-Perthes disease presenting with right wrist pain who was subsequently diagnosed with Kienbock's disease. The finding of multifocal osteonecrosis prompted testing for a hypercoagulable state that was positive for Factor V Leiden thrombophilia. A thorough literature review using Medline database was conducted to investigate associations between inherited hypercoagulable states and multifocal osteonecrosis...
September 2016: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/27687806/do-conversion-total-hip-arthroplasty-yield-comparable-results-to-primary-total-hip-arthroplasty
#15
Ran Schwarzkopf, Garwin Chin, Kelvin Kim, Dermot Murphy, Antonia F Chen
BACKGROUND: The incidence of hip fractures is growing with the increasing elderly population. Typically, hip fractures are treated with open reduction internal fixation, hemiarthroplasty, or total hip arthroplasty (THA). Failed hip fracture fixation is often salvaged by conversion THA. The total number of conversion THA procedures is also supplemented by its use in treating different failed surgical hip treatments such as acetabular fracture fixation, Perthes disease, slipped capital femoral epiphysis, and developmental dysplasia of the hip...
September 1, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27665487/factors-influencing-participation-in-health-behaviors-in-endometrial-cancer-survivors
#16
Sarah J Hardcastle, Rachael Glassey, Stuart Salfinger, Jason Tan, Paul Cohen
BACKGROUND: The study purpose was to investigate endometrial cancer survivors' health perceptions following cessation of active cancer treatment and to explore factors influencing participation in health-promoting behaviors. METHODS: Face-to-face interviews were conducted with participants who had completed active treatment of cancer within the previous 3 years. Participants were 22 endometrial cancer survivors (mean age = 62.55 years, SD = 7.08) at risk of cardiovascular disease who were recruited from 2 oncologists in Perth, Western Australia...
September 25, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/27648614/necrotic-bone-stimulates-proinflammatory-responses-in-macrophages-through-the-activation-of-toll-like-receptor-4
#17
Naga Suresh Adapala, Ryosuke Yamaguchi, Matthew Phipps, Olumide Aruwajoye, Harry K W Kim
In children with Legg-Calvé-Perthes disease, loss of blood supply to the femoral head results in ischemic osteonecrosis. Generally, macrophages play important roles in the inflammatory response to tissue necrosis, but their role in ischemic osteonecrosis of the femoral head (ONFH) is not known. The purpose of this study was to determine the macrophage-inflammatory responses after ONFH and the receptor mechanisms involved in sensing the necrotic bone, using a piglet model of Legg-Calvé-Perthes disease. Induction of ONFH resulted in increased numbers of CD14(+) macrophages (4...
September 17, 2016: American Journal of Pathology
https://www.readbyqxmd.com/read/27646418/do-radiographic-parameters-of-dysplasia-improve-to-normal-ranges-after-bernese-periacetabular-osteotomy
#18
Eduardo N Novais, Stephen Duncan, Jeffrey Nepple, Gail Pashos, Perry L Schoenecker, John C Clohisy
BACKGROUND: The goal of periacetabular osteotomy (PAO) is to improve the insufficient coverage of the femoral head and achieve joint stability without creating secondary femoroacetabular impingement. However, the complex tridimensional morphology of the dysplastic acetabulum presents a challenge to restoration of normal radiographic parameters. Accurate acetabular correction is important to achieve long-term function and pain improvement. There are limited data about the proportion of patients who have normal radiographic parameters restored after PAO and the factors associated with under- and overcorrection...
September 19, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27628762/-modified-pembersal-osteotomy-technique-with-lyophilized-human-allograft
#19
C Druschel, K Heck, C Kraft, R Placzek
OBJECTIVE: PemberSal osteotomy to improve femoral head coverage by rotating the acetabular roof ventrally and laterally. INDICATIONS: Insufficient coverage of the femoral head, and can be combined with other surgical procedures such as femoral intertrochanteric varus-derotation osteotomy and open reduction for developmental dysplasia and dislocation of the hip or to improve sphericity and containment in Legg-Calvé-Perthes disease. This specific acetabuloplasty can only be performed in patients with an open epiphyseal growth-plate...
December 2016: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/27621557/acetabular-anteversion-angle-from-early-stage-of-perthes-disease-to-adolescence
#20
Takashi Yoshida, Wook-Cheol Kim, Atsushi Nishida, Yoshinobu Oka, Toshiharu Shirai, Kazuya Ikoma, Keiichiro Ueshima, Hiroyoshi Fujiwara, Toshikazu Kubo
OBJECTIVE: This study aimed to assess acetabular anteversion angle (AAA) from the early stage of Perthes disease to adolescence. METHODS: Twenty-five patients treated conservatively were examined. Changes in AAA from initial to final measurement were compared between the two groups (G-group: Stulberg classes I and II; P-group: classes III and IV). RESULTS: In the G-group, AAA decreased significantly in the affected hip compared with the unaffected hip, whereas AAA decreased in both hips in the P-group...
December 2016: Journal of Orthopaedics
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