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Ramsay hunt

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https://www.readbyqxmd.com/read/27757380/concurrent-ramsay-hunt-syndrome-and-disseminated-herpes-zoster-in-a-patient-with-relapsed-chronic-lymphocytic-leukemia
#1
Ishita Chen, Raymond B Fohtung, Hanadi Ajam Oughli, Robert Bauer, Caline Mattar, William G Powderly, Mark S Thoelke
Ramsay Hunt Syndrome (RHS) is a rare complication of latent varicella-zoster virus (VZV) infection that can occur in immunocompetent host. It usually involves ipsilateral facial paralysis, ear pain and facial vesicles. Disseminated herpes zoster is another complication of VZV infection typically seen in immunocompromised hosts. We describe a patient with relapsed chronic lymphocytic leukemia (CLL) who presented simultaneously with RHS and disseminated herpes zoster. While other complications have been documented to coexist with RHS, to our knowledge, this is the first reported case in the literature of concurrent RHS with disseminated herpes zoster...
2016: IDCases
https://www.readbyqxmd.com/read/27746846/treatment-and-prognosis-of-facial-palsy-on-ramsay-hunt-syndrome-results-based-on-a-review-of-the-literature
#2
Rafael da Costa Monsanto, Aline Gomes Bittencourt, Natal José Bobato Neto, Silvia Carolina Almeida Beilke, Fabio Tadeu Moura Lorenzetti, Raquel Salomone
Introduction Ramsay Hunt syndrome is the second most common cause of facial palsy. Early and correct treatment should be performed to avoid complications, such as permanent facial nerve dysfunction. Objective The objective of this study is to review the prognosis of the facial palsy on Ramsay Hunt syndrome, considering the different treatments proposed in the literature. Data Synthesis We read the abstract of 78 studies; we selected 31 studies and read them in full. We selected 19 studies for appraisal...
October 2016: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/27643680/cerebrospinal-fluid-viral-load-and-biomarkers-of-neuronal-and-glial-cells-in-ramsay-hunt-syndrome
#3
Johan Lindström, Anna Grahn, Henrik Zetterberg, Marie Studahl
Reactivation of varicella zoster virus (VZV) can manifest with facial palsy diagnosed as Ramsay Hunt Syndrome (RHS) or Ramsay Hunt Syndrome zoster sine herpete (RHS-ZSH). These syndromes are associated with poor prognosis despite treatment with antivirals and corticosteroids. Concentrations of biomarkers such as neurofilament protein (NFL), S-100β protein and glial fibrillary acidic protein (GFAp) have previously been measured in cerebrospinal fluid (CSF) to assess neuronal damage and glial pathology. We employed immunochemical methods to measure concentrations of NFL, S-100β protein and GFAp in CSF from patients with RHS (n = 15) and RHS-ZSH (n = 13) diagnosed by detection of VZV DNA in the CSF by quantitative PCR, and compared with a control group (n = 52)...
September 19, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27504334/herpes-zoster-infection-involving-mandibular-division-of-trigeminal-nerve-and-ramsay-hunt-syndrome-with-meningitis-in-an-immunocompetent-patient-a-rare-association
#4
Vijayan Ganesan, Dhrubajyoti Bandyopadhyay, Suvrendu Sankar Kar, Cankatika Choudhury, Vivek Choudhary
Herpes zoster is a unilateral painful vesicular cutaneous eruption caused by the reactivation of the Varicella zoster virus. It commonly affects the older people and immunocompromised individuals. The dermatomes from T3 to L3 are most frequently involved. Its three stages include prodromal stage, active stage and chronic stage. The common complications of the infection include post-herpetic neuralgia, Ramsay Hunt syndrome, Guillain-Barre syndrome, transverse myelitis and encephalomyelitis. This case report summarizes a very rare association of herpes zoster meningitis with the involvement of mandibular division of the trigeminal nerve and facial nerve...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27497069/ramsay-hunt-syndrome
#5
N M Gupta, M P Parikh, S Panginikkod, V Gopalakrishnan
No abstract text is available yet for this article.
August 6, 2016: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/27435969/vertigo-with-sudden-hearing-loss-audio-vestibular-characteristics
#6
Jacob M Pogson, Rachael L Taylor, Allison S Young, Leigh A McGarvie, Sean Flanagan, G Michael Halmagyi, Miriam S Welgampola
Acute vertigo with sudden sensorineural hearing loss (SSNHL) is a rare clinical emergency. Here, we report the audio-vestibular test profiles of 27 subjects who presented with these symptoms. The vestibular test battery consisted of a three-dimensional video head impulse test (vHIT) of semicircular canal function and recording ocular and cervical vestibular-evoked myogenic potentials (oVEMP, cVEMP) to test otolith dysfunction. Unlike vestibular neuritis, where the horizontal and anterior canals with utricular function are more frequently impaired, 74 % of subjects with vertigo and SSNHL demonstrated impairment of the posterior canal gain (0...
October 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27366189/ramsay-hunt-syndrome-associated-with-central-nervous-system-involvement-in-an-adult
#7
Tommy L H Chan, Ana M Cartagena, Anne Marie Bombassaro, Seyed M Hosseini-Moghaddam
Ramsay Hunt syndrome associated with varicella zoster virus reactivation affecting the central nervous system is rare. We describe a 55-year-old diabetic female who presented with gait ataxia, right peripheral facial palsy, and painful vesicular lesions involving her right ear. Later, she developed dysmetria, fluctuating diplopia, and dysarthria. Varicella zoster virus was detected in the cerebrospinal fluid by polymerase chain reaction. She was diagnosed with Ramsay Hunt syndrome associated with spread to the central nervous system...
2016: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/27317379/varicella-zoster-virus-vzv-dna-in-serum-of-patients-with-vzv-central-nervous-system-infections
#8
Anna Grahn, Tomas Bergström, Jim Runesson, Marie Studahl
OBJECTIVES: Varicella-zoster virus (VZV) is a common viral agent causing central nervous system (CNS) infections, normally diagnosed by detection of VZV DNA in cerebrospinal fluid (CSF). Our aim was to investigate trends in VZV DNAemia in VZV CNS infections, which could potentially contribute to diagnosis and secondly, correlate the amount of VZV DNA in serum to severity of disease. METHODS: Seventy-two patients with VZV CNS infections diagnosed by detection of VZV DNA in CSF and concomitant neurological symptoms were included...
September 2016: Journal of Infection
https://www.readbyqxmd.com/read/27251418/herpetic-cranial-polyneuritis-mimicking-brain-stem-infarction-an-atypical-presentation-of-ramsay-hunt-syndrome
#9
Sneha Bharadwaj, Andrew Campbell Moffat, Brad Wood, Avinash Bharadwaj
An elderly man presented with severe right ear pain and discharge, hoarseness and dysphagia causing significant involuntary weight loss. Extensive investigations by varied specialties only highlighted right vocal cord palsy and right parotid lymphadenitis. Reassessment on transfer to a rehabilitation ward noted clinically subtle right Ramsay Hunt syndrome with multiple lower cranial nerve involvement. We illustrate a case of varicella zoster virus cranial polyneuritis with bulbar symptoms mimicking bulbar stroke, requiring percutaneous endoscopic gastrostomy feeds, with significant clinical and radiological recovery over 1 year...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27092925/magnetic-resonance-imaging-evidence-of-varicella-zoster-virus-polyneuropathy-involvement-of-the-glossopharyngeal-and-vagus-nerves-associated-with-ramsay-hunt-syndrome
#10
Hediye Pinar Gunbey, Gokhan Kutlar, Kerim Aslan, Asli Tanrivermis Sayit, Lutfi Incesu
The involvement of lower cranial nerve palsies is less frequent in Ramsay Hunt syndrome caused by varicella zoster virus (VZV). The authors report 1 of extremely rare patients of radiologically proven polyneuropathy of VZV infection with magnetic resonance imaging findings of VII, IX, and X cranial nerve involvement is a 62-year-old female patient, who initially presented with Ramsay Hunt syndrome. Varicella zoster virus infection should be considered even in patients who show unilateral palsy of the lower cranial nerves associated with laryngeal paralysis...
May 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/26864575/ramsay-hunt-syndrome
#11
Martha R Neagu, Sashank Prasad
No abstract text is available yet for this article.
June 2016: Practical Neurology
https://www.readbyqxmd.com/read/26779429/a-case-of-ramsay-hunt-syndrome-diagnosed-after-kidney-transplantation
#12
Yoo Min Park, Da Rae Kim, Ji Yoon Park, Seul Ki Kim, Se Yun Kim, Jin Sug Kim, Yu Ho Lee, Yang-Gyun Kim, Kyung-Hwan Jeong, Ju-Young Moon, Sang-Ho Lee, Chun-Gyoo Ihm, Tae-Won Lee
We report the first case of Ramsay Hunt syndrome (RHS) diagnosed after kidney transplantation in Korea. RHS is a disease caused by latent varicella-zoster characterized to involve geniculate ganglion of the seventh cranial nerve. Patients who have undergone kidney transplantation can be easily affected by viral infections because of their immune-compromised status. A 35-year-old man with hypertensive end-stage renal disease underwent kidney transplantation. Two months after surgery, the recipient was diagnosed with RHS and treated with antivirals and steroids...
December 2015: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/26568393/neurosyphilis-mimicking-ramsay-hunt-syndrome
#13
Tadashi Maeda, Sadako Yoshizawa, Takehisa Hirayama, Tomoo Saga, Kazuhiro Tateda, Yoshihisa Urita
A 36-year-old man presented with facial nerve palsy, hearing loss, vertigo and headache. He was initially diagnosed with Ramsay Hunt syndrome and treated with a systemic steroid and valaciclovir; however, his symptoms deteriorated. Serum rapid plasma reagin (RPR) and treponema pallidum hemagglutination tests were positive. Cerebrospinal fluid analysis revealed an elevated white blood cell count and positive RPR, confirming the diagnosis of neurosyphilis. Penicillin G (PCG) was administered, and his facial nerve function and headache improved...
2015: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/26435868/pediatric-ramsay-hunt-syndrome-analysis-of-three-cases
#14
İmran Aydoğdu, Enes Ataç, Ziya Saltürk, Yavuz Atar, Erdi Özdemir, Yavuz Uyar, Ahmet Arslanoğlu, Güler Berkiten
Ramsay Hunt syndrome (RHS) is a disorder characterized by herpetic eruptions on the auricle, facial paralysis, and vestibulocochlear dysfunction and is attributed to varicella zoster virus (VZV) infection in the geniculate ganglion. Although it is a common cause of acute peripheral facial paralysis, children are not usually affected. The diagnosis is based on history and physical findings. Treatment of RHS uses a combination of high-dose corticosteroids and acyclovir. This paper presents three cases diagnosed as RHS in the pediatric age group in association with the literature review...
2015: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/26367796/bet-inhibitor-resistance-emerges-from-leukaemia-stem-cells
#15
Chun Yew Fong, Omer Gilan, Enid Y N Lam, Alan F Rubin, Sarah Ftouni, Dean Tyler, Kym Stanley, Devbarna Sinha, Paul Yeh, Jessica Morison, George Giotopoulos, Dave Lugo, Philip Jeffrey, Stanley Chun-Wei Lee, Christopher Carpenter, Richard Gregory, Robert G Ramsay, Steven W Lane, Omar Abdel-Wahab, Tony Kouzarides, Ricky W Johnstone, Sarah-Jane Dawson, Brian J P Huntly, Rab K Prinjha, Anthony T Papenfuss, Mark A Dawson
Bromodomain and extra terminal protein (BET) inhibitors are first-in-class targeted therapies that deliver a new therapeutic opportunity by directly targeting bromodomain proteins that bind acetylated chromatin marks. Early clinical trials have shown promise, especially in acute myeloid leukaemia, and therefore the evaluation of resistance mechanisms is crucial to optimize the clinical efficacy of these drugs. Here we use primary mouse haematopoietic stem and progenitor cells immortalized with the fusion protein MLL-AF9 to generate several single-cell clones that demonstrate resistance, in vitro and in vivo, to the prototypical BET inhibitor, I-BET...
September 24, 2015: Nature
https://www.readbyqxmd.com/read/26183571/varicella-zoster-virus-specific-cell-mediated-immunity-in-ramsay-hunt-syndrome
#16
Shin-ichi Haginomori, Takahiro Ichihara, Atsuko Mori, Atsuko Kanazawa, Ryo Kawata, Huamin Tang, Yasuko Mori
OBJECTIVES/HYPOTHESIS: The etiology of Ramsay Hunt syndrome (Hunt syndrome) is reactivation of latent varicella-zoster virus (VZV) in the geniculate ganglion of the facial nerve, leading to neuritis. Although the mechanism of the VZV reactivation is unclear, one possibility is that the reactivation involves a low level of VZV-specific cell-mediated immunity (CMI). The aim of this study was to clarify the characteristics of the VZV-specific CMI in Hunt syndrome compared to that in Bell's palsy, and to obtain clues to its role in the development of Hunt syndrome...
January 2016: Laryngoscope
https://www.readbyqxmd.com/read/26062713/atypical-ramsay-hunt-syndrome
#17
Hsun-Hua Lee, Li-Kai Huang, Chaur-Jong Hu, Chih-Chung Chen
No abstract text is available yet for this article.
June 15, 2014: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/25989664/-ocular-and-cervical-vestibular-evoked-myogenic-potentials-in-patients-with-peripheral-vestibular-disorders
#18
Qing Zhang, Xinda Xu, Min Xu, Juan Hu, Jianmin Liang, Kimitaka Kaga
OBJECTIVE: To observe the ocular vestibular evoked myogenic potential (oVEMP) and the cervical vestibular evoked myogenic potential (cVEMP) in patients with vestibular diseases. METHOD: From March, 2011 to March, 2012, 13 patients (14 ears) with peripheral vestibular diseases were recruited. Each patient underwent conventional oVEMP and cVEMP examinations elicited by intensive air conducted sound (short tone burst, 500 Hz) in bilateral ears. RESULT: Thirteen cases (14 ears) were included in this study...
January 2015: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/25864001/a-rare-case-of-ramsay-hunt-syndrome-following-temporomandibular-joint-surgery
#19
H Lehman, H Rushinek
Surgical approaches to the temporomandibular joint (TMJ) have been designed specifically to minimize injury to the temporal branch of the facial nerve. In spite of this, facial nerve dysfunction occurs in 1-32% of patients undergoing TMJ surgery. Ramsay Hunt syndrome is characterized by peripheral facial paralysis that often involves other cranial nerves, mostly cranial nerve VIII. The pathology is attributed to the reactivation of latent varicella zoster virus in the geniculate ganglion. The diagnosis is based mostly on history and physical findings...
August 2015: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/25859138/neuro-ophthalmological-approach-to-facial-nerve-palsy
#20
REVIEW
Joana Portelinha, Maria Picoto Passarinho, João Marques Costa
Facial nerve palsy is associated with significant morbidity and can have different etiologies. The most common causes are Bell's palsy, Ramsay-Hunt syndrome and trauma, including surgical trauma. Incidence varies between 17 and 35 cases per 100,000. Initial evaluation should include accurate clinical history, followed by a comprehensive investigation of the head and neck, including ophthalmological, otological, oral and neurological examination, to exclude secondary causes. Routine laboratory testing and diagnostic imaging is not indicated in patients with new-onset Bell's palsy, but should be performed in patients with risk factors, atypical cases or in any case without resolution within 4 months...
January 2015: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
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