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https://www.readbyqxmd.com/read/29320381/a-brief-interview-to-detect-panic-attacks-and-panic-disorder-in-emergency-department-patients-with-cardiopulmonary-complaints
#1
Sharon C Sung, A John Rush, Arul Earnest, Leslie E C Lim, Maeve P P Pek, Joen M F Choi, Magdalene P K Ng, Marcus E H Ong
OBJECTIVES: Patients with panic-related anxiety often initially present to the emergency department (ED) complaining of respiratory or cardiac symptoms, but rates of detection of panic symptoms by ED physicians remain low. This study was undertaken to evaluate the relevance of panic attacks and panic disorder in ED patients who present with cardiopulmonary symptoms and to determine whether a brief symptom-based tool could be constructed to assist in rapid recognition of panic-related anxiety in the ED setting...
January 2018: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/29288854/lesional-temporal-lobe-epilepsy-beware-the-deceitful-panic-attack
#2
Kay O Kulason, Julia R Schneider, Ralph Rahme, Bidyut Pramanik, Derek Chong, John A Boockvar
BACKGROUND: Ganglioglioma is a rare, benign, intraaxial glioneuronal tumor, but a relatively common cause of pharmacoresistant temporal lobe epilepsy (TLE). Given its often nonspecific neuropsychiatric manifestations and frequently negative electroencephalographic workup, TLE can be easily misdiagnosed as a psychiatric disorder, particularly panic attacks. CASE DESCRIPTION: We present a case of a 17-year old boy who was found to have lesional TLE secondary to a left temporal ganglioglioma, 5 years after having been misdiagnosed with panic disorder and undergone ineffective and unnecessary psychotherapy...
December 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29258214/extraction-and-analysis-of-respiratory-motion-using-wearable-inertial-sensor-system-during-trunk-motion
#3
Apoorva Gaidhani, Kee S Moon, Yusuf Ozturk, Sung Q Lee, Woosub Youm
Respiratory activity is an essential vital sign of life that can indicate changes in typical breathing patterns and irregular body functions such as asthma and panic attacks. Many times, there is a need to monitor breathing activity while performing day-to-day functions such as standing, bending, trunk stretching or during yoga exercises. A single IMU (inertial measurement unit) can be used in measuring respiratory motion; however, breathing motion data may be influenced by a body trunk movement that occurs while recording respiratory activity...
December 17, 2017: Sensors
https://www.readbyqxmd.com/read/29241050/cytokine-alterations-in-panic-disorder-a-systematic-review
#4
REVIEW
Laiana Azevedo Quagliato, Antonio E Nardi
BACKGROUND: Panic disorder (PD) occurs in 3.4-4.7% of the general population. Although accumulating evidence suggests that some inflammatory processes play a role in the pathophysiology of mental disorders, very few studies have evaluated cytokine levels in patients with PD. The aim of the present study was to systematically review the characteristic cytokine profile of PD patients and discuss some possibilities for future trials on this common and disabling disorder. METHODS: A comprehensive literature search was carried out in PubMed and Web of Science databases (search terms: "panic disorder" or "panic attacks" and IL-1, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12, IL-13, TNF-alpha and INF-gamma)...
December 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29238581/a-spicy-status-synthetic-cannabinoid-spice-use-and-new-onset-refractory-status-epilepticus-a-case-report-and-review-of-the-literature
#5
Marc-Alain Babi, Christopher P Robinson, Carolina B Maciel
Synthetic cannabinoids refer to a wide variety of chemicals engineered to bind cannabinoid receptors (CB1 and CB2) and mimic the effects of delta-9-tetrahydrocanabinol. The potential for severe toxicity and limited in vivo data make synthetic cannabinoid intake an important public health and safety concern. Neurologic toxidromes associated with their use include mental status changes, panic attacks, memory distortions, acute psychosis (e.g. paranoia, delusional thoughts), disorganized behavior, and suicidal and homicidal thoughts...
2017: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29236893/pan-syrinx-and-syringomyelia
#6
Leonardo Palacios-Sánchez, Juan Sebastián Botero-Meneses, María Camila Vélez-Flórez
Many myths and legends have had a deep influence on modern language, and on modern medical vernacular. The terms "syrinx" and "panic"are two of the most characteristic examples and their use in neurology and other specialties is well known. This article reviews the history of these words in Greek mythology and their use in modern medicine. It is known by very few that clinical symptoms or conditions, such as syringomyelia and panic attacks, have a mythological origin in their definition and naming.
December 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/29213110/the-relationship-between-dlpfc-activity-during-unpredictable-threat-and-co2-induced-panic-symptoms
#7
Nicholas L Balderston, Jeffrey Liu, Roxann Roberson-Nay, Monique Ernst, Christian Grillon
Panic disorder is characterized by sudden, repeated, and unexpected attacks of intense fear and overwhelming anxiety about when another attack may strike. Patients with panic disorder and healthy individuals with a history of panic attacks show a hypersensitivity to unpredictable threats, suggesting a possible link between panic and sustained anxiety. The purpose of this study was to determine the degree to which induced symptoms of panic relate to fear and anxiety, as well as activity in the neural systems that mediate and regulate these affective states...
November 30, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/29202148/behavioral-health-consult-ensuring-prompt-recognition-and-treatment-of-panic-disorder
#8
Eric H Berko, Gabriela Feier
Lorna D was seen by her primary care physician as follow-up to a visit she made to the emergency department (ED). The 37 year old had gone to the ED 4 times in the previous year. Each time she presented with tachycardia, dyspnea, nausea, numbness in her extremities, and a fear that she was having a heart attack. In spite of negative work-ups at each visit (electrocardiogram, cardiac enzymes, complete blood count, toxicology screen, Holter monitoring), Ms. D was terrified that the ED doctors were missing something...
December 2017: Journal of Family Practice
https://www.readbyqxmd.com/read/29198411/epileptic-spasms-secondary-to-acute-cerebral-and-cerebellar-encephalitis
#9
Tohru Okanishi, Ayataka Fujimoto, Risa Hashimoto, Mitsuyo Nishimura, Sotaro Kanai, Miho Ogawa, Takayuki Suzuki, Hirotaka Motoi, Yukitoshi Takahashi, Hideo Enoki
BACKGROUND: Patients with infection-related acute encephalitis sometimes develop epilepsy in the chronic phase of the disease. Patients with postencephalitic epilepsy usually develop partial seizures due to the lesions generated by the encephalitis. We report a case who developed late-onset epileptic spasms after acute cerebral and cerebellar encephalitis. CASE REPORT: A 5-year-old girl showed severe tremor, gait ataxia, partial or generalized tonic-clonic seizures, hyperactivity, and panic attacks after a mild enterocolitis...
November 29, 2017: Brain & Development
https://www.readbyqxmd.com/read/29189171/inappropriate-sinus-tachycardia
#10
Mohammed Ruzieh, Abdelmoniem Moustafa, Ebrahim Sabbagh, Mohammad M. Karim, Saima Karim
Definition and diagnosis: Inappropriate Sinus Tachycardia (IST) is a clinical syndrome characterized by a sinus heart rate inexplicably higher than one hundred beats per minute at rest that is associated with symptoms like palpitations, dyspnea or dizziness in the absence of primary causes of tachycardia. The diagnosis requires exclusion of other causes of tachycardia including medications/substances (such as anti-cholinergic, beta-blocker withdrawal, caffeine, and alcohol) or medical conditions (such as panic attacks, pulmonary embolism, fever, hyperthyroidism, hypovolemia, anemia, and pain)...
November 29, 2017: Current Cardiology Reviews
https://www.readbyqxmd.com/read/29183829/the-rodent-versus-wild-snake-paradigm-as-a-model-for-studying-anxiety-and-panic-like-behaviors-face-construct-and-predictive-validities
#11
Tatiana Paschoalin-Maurin, Tayllon Dos Anjos-Garcia, Luiz Luciano Falconi-Sobrinho, Renato Leonardo de Freitas, Jade Pissamiglio Cysne Coimbra, Carlos Júlio Laure, Norberto Cysne Coimbra
Using an innovative approach to study the neural bases of psychiatric disorders, this study investigated the behavioral, morphological and pharmacological bases of panic attack-induced responses in a prey-versus-coral snake paradigm. Mesocricetus auratus was chronically treated with intraperitoneal administration of the selective serotonin uptake inhibitor paroxetine or the gamma aminobutyric acid (GABA)/benzodiazepine receptor agonist alprazolam at three different doses and were then confronted with a venomous coral snake (Micrurus frontalis, Reptilia, Colubridae)...
November 25, 2017: Neuroscience
https://www.readbyqxmd.com/read/29176864/health-assessment-of-french-university-students-and-risk-factors-associated-with-mental-health-disorders
#12
Antoine Tran, Laurie Tran, Nicolas Geghre, David Darmon, Marion Rampal, Diane Brandone, Jean-Michel Gozzo, Hervé Haas, Karine Rebouillat-Savy, Hervé Caci, Paul Avillach
OBJECTIVE: The first year of university is a particularly stressful period and can impact academic performance and students' health. The aim of this study was to evaluate the health and lifestyle of undergraduates and assess risk factors associated with psychiatric symptoms. MATERIALS AND METHODS: Between September 2012 and June 2013, we included all undergraduate students who underwent compulsory a medical visit at the university medical service in Nice (France) during which they were screened for potential diseases during a diagnostic interview...
2017: PloS One
https://www.readbyqxmd.com/read/29113874/effect-of-single-doses-of-pindolol-and-d-fenfluramine-on-flumazenil-induced-anxiety-in-panic-disorder-patients
#13
M Bernik, R T Ramos, L A B Hetem, F Graeff
The effects of the 5-HT1A receptor blocker pindolol and the 5-HT releasing and uptake blocking agent d-fenfluramine, both used as indirect serotonin agonists, on flumazenil-induced acute anxiety reactions were studied in panic disorder patients to test the hypothesis that serotonin (5-HT) inhibits neural systems mediating panic attacks. Thirty never treated or drug free PD patients (16 females) aged 22-49 y (mean±SD, 32.9±8) received single doses of d-fenfluramine (n=10; 30mg, p.o.), pindolol (n=10; 5mg, p...
November 4, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29111406/panic-like-escape-response-elicited-in-mice-by-exposure-to-co2-but-not-hypoxia
#14
Ailton Spiacci, Heloisa H Vilela-Costa, Ana Beatriz Sant'Ana, Gabriel Gripp Fernandes, Alana Tercino Frias, Glauber S Ferreira da Silva, José Antunes-Rodrigues, Hélio Zangrossi
Exposure to elevated concentrations of CO2 or hypoxia has been widely used in psychiatric research as a panic provoking stimulus. However, the use of these respiratory challenges to model panic-like responses in experimental animals has been less straightforward. Little data is available, from behavioral and endocrine perspectives, to support the conclusion that a marked aversive situation, such as that experienced during panic attacks, was evoked in these animals. We here compared the behavioral responses of male CB57BL/6 mice during exposure to 20% CO2 or 7% O2 and its consequence on plasma levels of corticosterone...
October 28, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29104945/distinct-responses-to-predictable-and-unpredictable-threat-in-anxiety-pathologies-effect-of-panic-attack
#15
Christian Grillon, Katherine O'Connell, Lynne Lieberman, Gabriella Alvarez, Marilla Geraci, Daniel S Pine, Monique Ernst
Background: Delineating specific clinical phenotypes of anxiety disorders is a crucial step toward better classification and understanding of these conditions. The present study sought to identify differential aversive responses to predictable and unpredictable threat of shock in healthy comparisons and in non-medicated anxiety patients with and without a history of panic attacks (PAs). Method: 143 adults (72 healthy controls; 71 patients with generalized anxiety disorder (GAD) or/and social anxiety disorder (SAD), 24 with and 47 without PAs) were exposed to three conditions: 1) predictable shocks signaled by a cue, 2) unpredictable shocks, and 3) no shock...
October 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29029561/women-with-psvt-are-often-misdiagnosed-referred-later-than-men-and-have-more-symptoms-after-ablation
#16
Carina Carnlöf, Marie Iwarzon, Mats Jensen-Urstad, Fredrik Gadler, Per Insulander
OBJECTIVES: Using a patient and gender perspective, this study evaluates the experiences and perspectives of referral for paroxysmal supraventricular tachycardia (PSVT), and symptoms, Health-Related Quality of Life (HRQOL) and functional impairment before and six months after ablation. DESIGN: This prospective study includes 214 (109 women) patients with PSVT who completed questionnaires before and after ablation addressing referral patterns, duration of arrhythmia, socioeconomic status, symptoms, HRQOL, and functional impairment...
October 13, 2017: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/29018160/dopamine-dysregulation-syndrome-in-parkinson-s-disease-a-systematic-review-of-published-cases
#17
Nicola Warren, Cullen O'Gorman, Alexander Lehn, Dan Siskind
OBJECTIVES: Dopamine dysregulation syndrome (DDS) is an uncommon complication of the treatment of Parkinson's disease, characterised by addictive behaviour and excessive use of dopaminergic medication. DDS may frequently go unrecognised or misdiagnosed. We aimed to clarify current understanding of presentation, risk factors, comorbidities and management of DDS. METHODS: Case reports were identified through a systematic search of databases (PubMed, Embase) with the following terms: dopaminergic dysregulation syndrome, hedonistic homeostatic dysregulation, dopamine/levodopa addiction...
October 10, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28939165/decrease-in-nmda-receptor-signalling-activity-in-the-anterior-cingulate-cortex-diminishes-defensive-behaviour-and-unconditioned-fear-induced-antinociception-elicited-by-gabaergic-tonic-inhibition-impairment-in-the-posterior-hypothalamus
#18
Luiz Luciano Falconi-Sobrinho, Tayllon Dos Anjos-Garcia, Ricardo de Oliveira, Norberto Cysne Coimbra
Acute γ-aminobutyric acid (GABA) disinhibition in the posterior hypothalamus (PH) elicits defensive reactions that are considered anxiety- and panic attack-like behaviour, and these defensive reactions are followed by antinociception. Evidence indicates that the PH connects with the medial prefrontal cortex, particularly the anterior cingulate cortex (ACC), which seems to regulate these unconditioned fear-induced defensive responses. However, few studies have shown the participation of cortical regions in the control of behavioural and antinociceptive responses organised by diencephalic structures...
September 19, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28922735/assessing-the-interplay-of-childhood-adversities-with-more-recent-stressful-life-events-and-conditions-in-predicting-panic-pathology-among-adults-from-the-general-population
#19
E Asselmann, J Stender, H J Grabe, J König, C O Schmidt, A O Hamm, C A Pané-Farré
BACKGROUND: Although research suggests that (a) childhood adversities and more recent stressful life events/conditions are risk factors for panic pathology and that (b) early life stress increases vulnerability to later psychopathology, it remains unclear whether childhood adversities amplify the association between more recent stressful life events/conditions and panic pathology. METHODS: Data were derived from a general population sample (Study of Health in Pomerania, SHIP)...
January 1, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28918162/how-high-level-of-anxiety-in-panic-disorder-can-interfere-in-working-memory-a-computer-simulation-and-electrophysiological-investigation
#20
Luiza Wanick Di Giorgio Silva, Danielle Aprigio, Jesse Di Giacomo, Mariana Gongora, Henning Budde, Juliana Bittencourt, Mauricio Cagy, Silmar Teixeira, Pedro Ribeiro, Marcele Regine de Carvalho, Rafael Freire, Antonio Egidio Nardi, Luis Fernando Basile, Bruna Velasques
Panic disorder (PD) is characterized by repeated and unexpected attacks of intense anxiety, which are not restricted to a determined situation or circumstance. The coherence function has been used to investigate the communication among brain structures through the quantitative EEG (qEEG). The objective of this study is to analyze if there is a difference in frontoparietal gamma coherence (GC) between panic disorder patients (PDP) and healthy controls (HC) during the Visual oddball paradigm; and verify if high levels of anxiety (produced by a computer simulation) affect PDP's working memory...
December 2017: Journal of Psychiatric Research
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