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Coronary computed tomography

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https://www.readbyqxmd.com/read/28812383/evaluation-of-relationship-between-coronary-artery-status-evaluated-by-coronary-computed-tomography-angiography-and-development-of-cardiomyopathy-in-carbon-monoxide-poisoned-patients-with-myocardial-injury-a-prospective-observational-study
#1
Yong Sung Cha, Hyun Kim, Yoonsuk Lee, Woocheol Kwon, Jung-Woo Son, Hyun Youk, Hyung Il Kim, Oh Hyun Kim, Kyung Hye Park, Kyoung-Chul Cha, Kang Hyun Lee, Sung Oh Hwang
OBJECTIVES: Whether coronary artery changes are a main mechanism in the development of carbon monoxide (CO)-induced cardiomyopathy remains unknown. We investigated the effects of coronary artery stenosis on the presence or patterns of cardiomyopathy in CO-poisoned patients with myocardial injury defined as elevation of troponin I. MATERIALS AND METHODS: This prospective observational study collected data from consecutive patients who were diagnosed with CO poisoning and myocardial injury during the 24-month study period...
August 16, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28808939/comparison-of-left-ventricular-shape-by-gated-spect-imaging-in-diabetic-and-nondiabetic-patients-with-normal-myocardial-perfusion-a-propensity-score-analysis
#2
Carmela Nappi, Valeria Gaudieri, Wanda Acampa, Roberta Assante, Emilia Zampella, Ciro Gabriele Mainolfi, Mario Petretta, Guido Germano, Alberto Cuocolo
BACKGROUND: Diabetes mellitus induces structural and functional cardiac alterations that can result in heart failure. Left ventricular (LV) shape is a dynamic component of cardiac geometry influencing its contractile function. However, few data are available comparing LV shape index in diabetic and nondiabetic patients without overt coronary artery disease after balancing for coronary risk factors. METHODS: We studied 1168 patients with normal myocardial perfusion and normal LV ejection fraction on stress gated single-photon emission computed tomography (SPECT) imaging...
August 14, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28805032/improving-outcomes-after-cabg-and-pci
#3
EDITORIAL
Robert D Safian
Within 1 year of coronary artery bypass surgery , 64% of percutaneous coronary interventions were performed for graft failure and 36% for native vessel disease. Predictors of graft failure were small diameter of the graft and native vessel, poor distal run-off, and disease distal to the graft. In the near future, cardiac computed tomography angiography (CCTA) and fractional flow reserve by CT (FFRct) will incorporate accurate determination of coronary anatomy and the presence and extent of myocardial ischemia...
August 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28804238/percutaneous-closure-of-the-aorto-ostial-origin-of-a-coronary-artery-saphenous-bypass-graft-with-a-large-pseudoaneurysm-using-the-amplatzer-muscular-ventricular-septal-defect-occluder
#4
Nicolas W Shammas, Majid Z Chammas, Jon Robken, Dale Geiss
We report the case of a 76-year-old male patient with a history of coronary artery bypass graft surgery presented with a large pseudoaneurysm emerging from a previously occluded saphenous bypass graft (SVG). A largely contained hematoma is seen in the mediastinum on computed tomography angiography (CTA) of the chest. Flow was seen from the ascending aorta into the pseudoaneurysm through the aorto-ostial opening of the bypass graft. Closure of the aorto-ostial origin of the graft was performed using the AMPLATZER muscular ventricular septal defect (VSD) occluder (St Jude's Medical, St...
September 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/28803421/quantitative-coronary-plaque-analysis-predicts-high-risk-plaque-morphology-on-coronary-computed-tomography-angiography-results-from-the-romicat-ii-trial
#5
Ting Liu, Pál Maurovich-Horvat, Thomas Mayrhofer, Stefan B Puchner, Michael T Lu, Khristine Ghemigian, Pieter H Kitslaar, Alexander Broersen, Amit Pursnani, Udo Hoffmann, Maros Ferencik
Semi-automated software can provide quantitative assessment of atherosclerotic plaques on coronary CT angiography (CTA). The relationship between established qualitative high-risk plaque features and quantitative plaque measurements has not been studied. We analyzed the association between quantitative plaque measurements and qualitative high-risk plaque features on coronary CTA. We included 260 patients with plaque who underwent coronary CTA in the Rule Out Myocardial Infarction/Ischemia Using Computer Assisted Tomography (ROMICAT) II trial...
August 12, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28802566/alcohol-use-and-cardiovascular-disease-risk-in-patients-with-nonalcoholic-fatty-liver-disease
#6
Lisa B VanWagner, Hongyan Ning, Norrina B Allen, Veeral Ajmera, Cora E Lewis, John Jeffrey Carr, Donald M Lloyd-Jones, Norah A Terrault, Juned Siddique
BACKGROUND & AIMS: Cardiovascular disease (CVD) is the leading cause of death among patients with non-alcoholic fatty liver disease (NAFLD). Moderate drinking (vs abstinence) is associated with lower risk of CVD in the general population. We assessed whether alcohol use is associated with CVD risk in patients with NAFLD. METHODS: We analyzed data from participants in the Coronary Artery Risk Development in Young Adults longitudinal cohort study of 5115 black and white young adults, 18-30 years old, recruited from 4 cities in the United States from 1985 through 1986...
August 9, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28801799/double-versus-single-source-left-sided-coronary-revascularization-using-bilateral-internal-thoracic-artery-graft-alone
#7
Giuseppe Gatti, Gianluca Castaldi, Marco Morosin, Irena Tavcar, Manuel Belgrano, Bernardo Benussi, Gianfranco Sinagra, Aniello Pappalardo
Left-sided coronary revascularization with bilateral internal thoracic artery (BITA) graft is performed usually either with an in situ (double source) or Y-graft configuration (single source). Two hundred fifty-three (mean age, 67.1 ± 9.5 years) patients underwent isolated left-sided coronary revascularization with BITA graft alone at the present authors' institution (2000-2015). Skeletonized BITA grafts were used either in an in situ (n = 199) or Y-graft configuration (n = 54). Forty pairs were identified with the propensity score-matching...
August 11, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28800951/evaluation-of-a-high-concentrated-contrast-media-injection-protocol-in-combination-with-low-tube-current-for-dose-reduction-in-coronary-computed-tomography-angiography-a-randomized-two-center-prospective-study
#8
Yibo Sun, Yanqing Hua, Mingpeng Wang, Dingbiao Mao, Xiu Jin, Cheng Li, Kailei Shi, Jianrong Xu
RATIONALE AND OBJECTIVES: The study aimed to prospectively evaluate the radiation dose reduction potential and image quality (IQ) of a high-concentration contrast media (HCCM) injection protocol in combination with a low tube current (mAs) in coronary computed tomography angiography. MATERIALS AND METHODS: Eighty-one consecutive patients (mean age: 62 years; 34 females; body mass index: 18-31) were included and randomized-assigned into two groups. All computed tomography (CT) examinations were performed in two groups with the same tube voltage (100 kV), flow rate of contrast medium (5...
August 8, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28797768/ct-coronary-angiography-findings-in-non-atherosclerotic-coronary-artery-diseases
#9
REVIEW
Z Zhou, L Xu, N Zhang, H Wang, W Liu, Z Sun, Z Fan
Non-atherosclerotic coronary artery diseases are being increasingly recognised as causes of acute coronary events. Invasive coronary angiography frequently fails to identify the abnormalities in the proximal course of coronary arteries and coronary wall, while computed tomography coronary angiography (CTCA) allows for acquisition of more detailed information. CTCA serves as a reliable method for evaluating patients with non-atherosclerotic coronary artery diseases. The purpose of this article is to provide an overview of non-atherosclerotic abnormalities that may be demonstrated on CTCA...
August 7, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28797740/framework-for-detection-and-localization-of-coronary-non-calcified-plaques-in-cardiac-cta-using-mean-radial-profiles
#10
Muhammad Moazzam Jawaid, Atif Riaz, Ronak Rajani, Constantino Carlos Reyes-Aldasoro, Greg Slabaugh
BACKGROUND AND OBJECTIVE: The high mortality rate associated with coronary heart disease (CHD) has driven intensive research in cardiac imaging and image analysis. The advent of computed tomography angiography (CTA) has turned non-invasive diagnosis of cardiovascular anomalies into reality as calcified coronary plaques can be easily identified due to their high intensity values. However, the detection of non-calcified plaques in CTA is still a challenging problem because of lower intensity values, which are often similar to the nearby blood and muscle tissues...
August 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28797406/ct-detected-growth-of-coronary-artery%C3%A2-calcification-in-asymptomatic-middle-aged-subjects-and-association-with-15-biomarkers
#11
Søren Zöga Diederichsen, Mette Hjortdal Grønhøj, Hans Mickley, Oke Gerke, Flemming Hald Steffensen, Jess Lambrechtsen, Niels Peter Rønnow Sand, Lars Melholt Rasmussen, Michael Hecht Olsen, Axel Diederichsen
OBJECTIVES: This study sought to determine the incidence and progression of coronary artery calcification (CAC) in asymptomatic middle-aged subjects and to evaluate the value of a broad panel of biomarkers in the prediction of CAC growth. BACKGROUND: CAC continues to be a major risk factor, but the value of biochemical markers in predicting CAC incidence and progression remains unresolved. METHODS: At baseline, 1,227 men and women underwent traditional risk assessment and a computed tomography (CT) scan to determine the CAC score...
August 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28797405/assessment-of-coronary-calcium-density-on-noncontrast-computed-tomography
#12
EDITORIAL
Daniel S Berman, Yoav Arnson, Alan Rozanski
No abstract text is available yet for this article.
August 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28797402/the-identification-of-calcified-coronary-plaque-is-associated-with-initiation-and-continuation-of-pharmacological-and-lifestyle-preventive-therapies-a-systematic-review-and-meta-analysis
#13
Ankur Gupta, Emily Lau, Ravi Varshney, Edward A Hulten, Michael Cheezum, Marcio S Bittencourt, Michael J Blaha, Nathan D Wong, Roger S Blumenthal, Matthew J Budoff, Craig A Umscheid, Khurram Nasir, Ron Blankstein
OBJECTIVES: The aim of this study was to assess the odds of initiation or continuation of pharmacological and lifestyle preventive therapies in patients with nonzero versus zero coronary artery calcium (CAC) score detected on cardiac computed tomography. BACKGROUND: Detection of calcified coronary plaque could serve as a motivational tool for physicians and patients to intensify preventive therapies. METHODS: We searched PubMed, EMBASE (Excerpta Medica database), Web of Science, Cochrane CENTRAL (Cochrane central register of controlled trials), ClinicalTrials...
August 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28794138/quantitative-assessment-of-coronary-microvascular-function-dynamic-single-photon-emission-computed-tomography-positron-emission-tomography-ultrasound-computed-tomography-and-magnetic-resonance-imaging
#14
Attila Feher, Albert J Sinusas
A healthy, functional microcirculation in combination with nonobstructed epicardial coronary arteries is the prerequisite of normal myocardial perfusion. Quantitative assessment in myocardial perfusion and determination of absolute myocardial blood flow can be achieved noninvasively using dynamic imaging with multiple imaging modalities. Extensive evidence supports the clinical value of noninvasively assessing indices of coronary flow for diagnosing coronary microvascular dysfunction; in certain diseases, the degree of coronary microvascular impairment carries important prognostic relevance...
August 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28792138/association-of-inter-arm-systolic-blood-pressure-difference-with-coronary-atherosclerotic-disease-burden-using-calcium-scoring
#15
Ae Young Her, Kyoung Im Cho, Scot Garg, Yong Hoon Kim, Eun Seok Shin
PURPOSE: There are no sufficient data on the correlation between inter-arm blood pressure (BP) difference and coronary atherosclerosis found using coronary artery calcium score (CACS). We aimed to investigate if the increased difference in inter-arm BP is independently associated with severity of CACS. MATERIALS AND METHODS: Patients who had ≥3 cardiovascular risk factors or an intermediate Framingham Risk Score (FRS; ≥10) were enrolled. Inter-arm BP difference was defined as the absolute difference in BP in both arms...
September 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28792136/impact-of-follow-up-ischemia-on-myocardial-perfusion-single-photon-emission-computed-tomography-in-patients-with-coronary-artery-disease
#16
Se Hun Kang, Hyo In Choi, Young Hak Kim, Eun Young Lee, Jung Min Ahn, Seungbong Han, Pil Hyung Lee, Jae Hyung Roh, Sung Han Yun, Duk Woo Park, Soo Jin Kang, Seung Whan Lee, Cheol Whan Lee, Dae Hyuk Moon, Seong Wook Park, Seung Jung Park
PURPOSE: Few studies have reported on predicting prognosis using myocardial perfusion single-photon emission computed tomography (SPECT) during coronary artery disease (CAD) treatment. Therefore, we aimed to assess the clinical implications of myocardial perfusion SPECT during follow-up for CAD treatment. MATERIALS AND METHODS: We enrolled 1153 patients who had abnormal results at index SPECT and underwent follow-up SPECT at intervals ≥6 months. Major adverse cardiac events (MACE) were compared in overall and 346 patient pairs after propensity-score (PS) matching...
September 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28791822/a-coronary-proatherosclerotic-marker-pregnancy-associated-plasma-protein-a-and-its-association-with-coronary-calcium-score-and-carotid-intima-media-thickness
#17
Abdullah Guven, Bora Demircelik, Ozgul Malcok Gurel, Okan Er, Halil Ibrahim Aydin, Alper Bozkurt
BACKGROUND: Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for the greatest number of deaths in westernized societies, with numbers increasing at a marked rate in developing countries. Coronary calcium score (CCS), carotid intima-media thickness (CIMT) and pregnancy-associated plasma protein A (PAPP-A) are predictors for the development of atherosclerosis. OBJECTIVES: This study was aimed to investigate the relationship between CCS, CIMT and PAPP-A for earlier diagnosis of atherosclerosis...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28790243/-valve-replacement-for-severe-aortic-stenosis-in-a-patient-with-tangier-disease
#18
Atsushi Tamura, Takamichi Yoshizaki, Sho Kusadokoro
We report a case of severe aortic valve stenosis in a patient with Tangier disease. A 64-year-old female was diagnosed with Tangier disease on the basis of gene mutation. The serum levels of total cholesterol and high-density lipoprotein were 124 mg/dl and 4.3 mg/dl, respectively. She had a symptom of dyspnea and echocardiography revealed severe aortic valve stenosis with the maximum gradient of 60.5 mmHg. Chest computed tomography showed severe calcification of the ascending aorta and the aortic root. Aortic valve replacement using a bioprosthetic valve was performed...
August 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28789941/effect-of-the-ratio-of-coronary-arterial-lumen-volume-to-left-ventricle-myocardial-mass-derived-from-coronary-ct-angiography-on-fractional-flow-reserve
#19
Charles A Taylor, Sara Gaur, Jonathon Leipsic, Stephan Achenbach, Daniel S Berman, Jesper M Jensen, Damini Dey, Hans Erik Bøtker, Hyun Jin Kim, Sophie Khem, Alan Wilk, Christopher K Zarins, Hiram Bezerra, John Lesser, Brian Ko, Jagat Narula, Amir Ahmadi, Kristian A Øvrehus, Fred St Goar, Bernard De Bruyne, Bjarne L Nørgaard
BACKGROUND: We hypothesize that in patients with suspected coronary artery disease (CAD), lower values of the ratio of total epicardial coronary arterial lumen volume to left ventricular myocardial mass (V/M) result in lower fractional flow reserve (FFR). METHODS: V/M was computed in 238 patients from the NXT trial who underwent coronary computed tomography angiography (CTA), quantitative coronary angiography (QCA) and FFR measurement in 438 vessels. Nitroglycerin was administered prior to CT, QCA and FFR acquisition...
August 3, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28777120/multicenter-aids-cohort-study-quantitative-coronary-plaque-progression-study-rationale-and-design
#20
Rine Nakanishi, Wendy S Post, Kazuhiro Osawa, Eranthi Jayawardena, Michael Kim, Nasim Sheidaee, Negin Nezarat, Sina Rahmani, Nicholas Kim, Nicolai Hathiramani, Shriraj Susarla, Frank Palella, Mallory Witt, Michael J Blaha, Todd T Brown, Lawrence Kingsley, Sabina A Haberlen, Christopher Dailing, Matthew J Budoff
BACKGROUND AND AIM: The association of HIV with coronary atherosclerosis has been established; however, the progression of coronary atherosclerosis over time among participants with HIV is not well known. The Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study is a large prospective multicenter study quantifying progression of coronary plaque assessed by serial coronary computed tomography angiography (CTA). PATIENTS AND METHODS: HIV-infected and uninfected men who were enrolled in the Multicenter AIDS Cohort Study Cardiovascular Substudy were eligible to complete a follow-up contrast coronary CTA 3-6 years after baseline...
August 2, 2017: Coronary Artery Disease
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