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Coronary computed tomography

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https://www.readbyqxmd.com/read/28445682/atrial-fibrillation-diagnostic-accuracy-of-coronary-ct-angiography-performed-with-a-whole-heart-230-%C3%A2%C2%B5m-spatial-resolution-ct-scanner
#1
Daniele Andreini, Gianluca Pontone, Saima Mushtaq, Edoardo Conte, Marco Perchinunno, Marco Guglielmo, Valentina Volpato, Andrea Annoni, Andrea Baggiano, Alberto Formenti, Maria Elisabetta Mancini, Virginia Beltrama, Valentina Ditali, Alessandro Campari, Cesare Fiorentini, Antonio L Bartorelli, Mauro Pepi
Purpose To assess image quality, interpretability, diagnostic accuracy, and radiation exposure of a computed tomography (CT) scanner with 16-cm coverage and 230-µm spatial resolution at coronary artery evaluation in patients with atrial fibrillation (AF) by using invasive coronary angiography (ICA) as the reference method and to compare the results with those obtained in patients with sinus rhythm (SR). Materials and Methods Written informed consent and institutional ethics committee approval were obtained...
April 26, 2017: Radiology
https://www.readbyqxmd.com/read/28444638/nuclear-cardiology-are-we-using-the-right-protocols-and-tracers-the-right-way
#2
REVIEW
Maurizio Dondi, Thomas Pascual, Diana Paez, Andrew J Einstein
The field of nuclear cardiology has changed considerably over recent years, with greater attention paid to safety and radiation protection issues. The wider usage of technetium-99m (Tc-99m)-labeled radiopharmaceuticals for single-photon emission computed tomography (SPECT) imaging using gamma cameras has contributed to better quality studies and lower radiation exposure to patients. Increased availability of tracers and scanners for positron emission tomography (PET) will help further improve the quality of studies and quantify myocardial blood flow and myocardial flow reserve, thus enhancing the contribution of non-invasive imaging to the management of coronary artery disease...
April 25, 2017: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://www.readbyqxmd.com/read/28444153/computed-tomography-derived-fractional-flow-reserve-testing-in-stable-patients-with-typical-angina-pectoris-influence-on-downstream-rate-of-invasive-coronary-angiography
#3
Jesper Møller Jensen, Hans Erik Bøtker, Ole Norling Mathiassen, Erik Lerkevang Grove, Kristian Altern Øvrehus, Kamilla Bech Pedersen, Christian Juhl Terkelsen, Evald Høj Christiansen, Michael Maeng, Jonathon Leipsic, Anne Kaltoft, Lars Jakobsen, Jacob Thorsted Sørensen, Troels Thim, Steen Dalby Kristensen, Lars Romer Krusell, Bjarne Linde Nørgaard
Aims: To assess the use of downstream coronary angiography (ICA) and short-term safety of frontline coronary CT angiography (CTA) with selective CT-derived fractional flow reserve (FFRCT) testing in stable patients with typical angina pectoris. Methods and results: Between 1 January 2016 and 30 June 2016 all patients (N = 774) referred to non-emergent ICA or coronary CTA at Aarhus University Hospital on a suspicion of CAD had frontline CTA performed. Downstream testing and treatment within 3 months and adverse events ≥90 days were registered...
April 20, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28442659/diagnostic-accuracy-of-endocardial-to-epicardial-myocardial-blood-flow-ratio-for-the-detection-of-significant-coronary-artery-disease-with-dynamic-myocardial-perfusion-dual-source-computed-tomography
#4
Yoshitaka Goto, Kakuya Kitagawa, Mio Uno, Shiro Nakamori, Tatsuro Ito, Naoki Nagasawa, Kaoru Dohi, Hajime Sakuma
BACKGROUND: Previous dynamic stress computed tomography perfusion (CTP) studies used absolute myocardial blood flow (MBF in mL/100 g/min) as a threshold to discriminate flow-limiting coronary artery disease (CAD), but absolute MBF can be vary because of multiple factors. The aim of this study was to compare the diagnostic performance of absolute MBF and the transmural perfusion ratio (TPR) for the detection of flow-limiting CAD, and to clarify the influence of CT delayed enhancement (CTDE) on the diagnostic performance of CTP...
April 25, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28442125/relation-of-risk-factors-and-abdominal-aortic-calcium-to-progression-of-coronary-artery-calcium-from-the-framingham-heart-study
#5
Oyere K Onuma, Karol Pencina, Saadia Qazi, Joseph M Massaro, Ralph B D'Agostino, Michael L Chuang, Caroline S Fox, Udo Hoffmann, Christopher J O'Donnell
Coronary artery calcium (CAC) and abdominal aortic calcium (AAC) on multidetector computed tomography (MDCT) permit assessment of the presence and burden of coronary and systemic atherosclerosis. Risk factors for progression of CAC and AAC and the association of AAC with CAC progression have not been well characterized in a community-dwelling cohort. We studied 1,959 asymptomatic participants from the Framingham Heart Study who underwent serial MDCT scans with a median interval of 6.1 years. Primary outcomes were (a) the incidence of CAC and AAC (CAC >0 and AAC >0 with baseline CAC = 0 and AAC = 0) and (b) absolute progression of CAC (CAC > baseline CAC and AAC > baseline AAC)...
May 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28441929/endothelial-progenitor-cells-and-plaque-burden-in-stented-coronary-artery-segments-an-optical-coherence-tomography-study-six-months-after-elective-pci
#6
Sylvia Otto, Kristina Nitsche, Christian Jung, Aleh Kryvanos, Andrey Zhylka, Kerstin Heitkamp, Juan-Luis Gutiérrez-Chico, Björn Goebel, P Christian Schulze, Hans R Figulla, Tudor C Poerner
BACKGROUND: Endothelial progenitor cells (EPC) are involved in neovascularization and endothelial integrity. They might be protective in atherosclerosis. Optical coherence tomography (OCT) is a precise intracoronary imaging modality that allows assessment of subintimal plaque development. We evaluated the influence of EPC on coronary plaque burden in stable disease and implemented a novel computational plaque analysis algorithm using OCT. METHODS: Forty-three patients (69...
April 26, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28441695/increased-high-risk-coronary-plaque-burden-is-associated-with-arterial-stiffness-in-patients-with-type-2-diabetes-without-clinical-signs-of-coronary-artery-disease-a-computed-tomography-angiography-study
#7
Kristian L Funck, Esben Laugesen, Kristian Øvrehus, Jesper M Jensen, Bjarne L Nørgaard, Damini Dey, Troels K Hansen, Per L Poulsen
OBJECTIVES: Arterial stiffness and subclinical coronary atherosclerosis may yield valuable information on cardiovascular risk. We aimed to characterize coronary atherosclerosis in asymptomatic patients with type 2 diabetes and healthy controls and to investigate the association between baseline arterial stiffness and coronary plaque volumes after 5-year follow-up. METHODS: Data from 45 patients and 61 matched controls were available for coronary plaque assessment...
June 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28439736/early-cardiac-perfusion-defects-after-left-sided-radiation-therapy-for-breast-cancer-is-there-a-volume-response
#8
REVIEW
Orit Kaidar-Person, Timothy M Zagar, Jorge Daniel Oldan, Jason Matney, Ellen L Jones, Shiva Das, Brian C Jensen, Richard C Zellars, Terence Z Wong, Lawrence B Marks
PURPOSE: Cardiac single-photon emission computed tomography (SPECT) is often used to identify defects in myocardial perfusion due to atherosclerotic coronary artery disease. It was also used in studies to evaluate radiation therapy (RT)-associated cardiac abnormalities. In the current review, we aim to evaluate the rates of post-RT cardiac SPECT early perfusion abnormalities and relate this to the irradiated left ventricular volume. METHODS: The studies cited in this systematic review were identified using the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines...
April 21, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28437443/relative-predictive-value-of-lung-cancer-screening-ct-versus-myocardial-perfusion-attenuation-correction-ct-in-the-evaluation-of-coronary-calcium
#9
Grant Bailey, Abigail Healy, Bryan D Young, Esseim Sharma, Judith Meadows, Hyung J Chun, Wen-Chih Wu, Gaurav Choudhary, Alan R Morrison
Coronary artery calcium scores (CACS) from lung cancer screening computed tomography (LCSCT) or myocardial perfusion attenuation correction computed tomography (ACCT) are not routinely performed or reported. CACS from LCSCT and ACCT have not been directly compared in the same patient population. We identified 66 patients who underwent both LCSCT (non-gated) and ECG-gated cardiac CT (CCT) within a 2-year span. Of this population, 40 subjects had also undergone ACCT. Using the Agatston method, CACS for 264 individual vessels from the LCSCT population and for 160 vessels from ACCT population were calculated and evaluated for agreement with ECG-gated CCT as the gold standard...
2017: PloS One
https://www.readbyqxmd.com/read/28433355/the-no-touch-saphenous-vein-graft-in-elderly-coronary-bypass-patients-with-multiple-comorbidities-is-a-promising-conduit-to-substitute-the-left-internal-thoracic-artery
#10
Ninos Samano, Håkan Geijer, Lennart Bodin, Mikael Arbeus, John D Mannion, Michael Dashwood, Domingos Souza
OBJECTIVES: We investigated the patency rates of no-touch saphenous vein grafts anastomosed to the left anterior descending artery compared with the left internal thoracic artery. Further, we compared the patency of no-touch vein grafts to the left anterior descending artery with the patency of no-touch vein grafts to other coronary arteries. METHODS: Of 2635 consecutive patients undergoing coronary artery bypass grafting between 2003 and 2008, 168 (6.3%) were given at least a saphenous vein graft to the left anterior descending artery to avoid harvesting complications in high-risk patients or in response to a left internal thoracic artery injury...
March 24, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28432820/the-impact-of-small-motion-on-the-visualization-of-coronary-vessels-and-lesions-in-cardiac-ct-a-simulation-study
#11
Francisco Contijoch, J Webster Stayman, Elliot R McVeigh
PURPOSE: Coronary x-ray computed tomography angiography (CCTA) is used to non-invasively assess coronary artery geometry and has, combined with computational modeling, demonstrated the potential to identify physiologically significant lesions. These measurements require robust and accurate coronary imaging and delineation of vessels in the presence of small motion. This simulation study characterizes the impact of small, uncorrected vessel drifts during data acquisition on the assessment of vessel intensity, diameter, and shape...
April 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/28431861/cardiac-computed-tomography-derived-myocardial-mass-at-risk-using-the-voronoi-based-segmentation-algorithm-a-histological-validation-study
#12
Seiko Ide, Satoru Sumitsuji, Osamu Yamaguchi, Yasushi Sakata
BACKGROUND: Myocardial mass at risk (MMAR) is an important predictor of adverse cardiac events in patients with ischemic heart disease. This study aims to validate the accuracy of MMAR calculated from cardiac computed tomography (CCT) data using the Voronoi-based segmentation algorithm in comparison with actual MMAR measured on ex-vivo swine hearts prepared by injecting a dye into the coronary arteries. METHODS: Fifteen extracted swine hearts had India ink injected into one of the major coronary arteries...
April 18, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28430739/downstream-indication-to-revascularization-following-hybrid-cardiac-pet-mri-preliminary-results
#13
Julien Priamo, Dionysos Adamopoulos, Oliver Rager, Angela Frei, Stephane Noble, David Carballo, Osman Ratib, René Nkoulou
BACKGROUND: Hybrid PET/MRI allows the acquisition of both fluorine-18-fluorodeoxyglucose (F-FDG) PET and cardiac magnetic resonance (CMR) during one session. Whether this will result in different referral to coronary revascularization (CR) is unknown. We compared this new hybrid method with all-nuclear/all-CMR methods in the assessment of viable myocardium and in downstream referral to CR. PATIENTS AND METHODS: Overall, 12 patients with rest perfusion defects on a single photon emission computed tomography (SPECT) were recruited for cardiac viability assessment using a PET/MRI device...
April 20, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28428195/progression-of-coronary-artery-calcium-and-incident-heart-failure-the-multi-ethnic-study-of-atherosclerosis
#14
Hooman Bakhshi, Bharath Ambale-Venkatesh, Xiaoying Yang, Mohammad R Ostovaneh, Colin O Wu, Matthew Budoff, Hossein Bahrami, Nathan D Wong, David A Bluemke, João A C Lima
BACKGROUND: Although the association between coronary artery calcium (CAC) and future heart failure (HF) has been shown previously, the value of CAC progression in the prediction of HF has not been investigated. In this study, we investigated the association of CAC progression with subclinical left ventricular (LV) dysfunction and incident HF in the Multi-Ethnic Study of Atherosclerosis. METHODS AND RESULTS: The Multi-Ethnic Study of Atherosclerosis is a population-based study consisting of 6814 men and women aged 45 to 84, free of overt cardiovascular disease at enrollment, who were recruited from 4 ethnicities...
April 20, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28427597/intentional-percutaneous-laceration-of%C3%A2-the%C3%A2-anterior-mitral-leaflet-to-prevent%C3%A2-outflow%C3%A2-obstruction-during-transcatheter-mitral-valve-replacement-first-in-human%C3%A2-experience
#15
Vasilis C Babaliaros, Adam B Greenbaum, Jaffar M Khan, Toby Rogers, Dee Dee Wang, Marvin H Eng, William W O'Neill, Gaetano Paone, Vinod H Thourani, Stamatios Lerakis, Dennis W Kim, Marcus Y Chen, Robert J Lederman
OBJECTIVES: This study sought to use a new catheter technique to split the anterior mitral valve leaflet (AML) and prevent iatrogenic left ventricular outflow tract (LVOT) obstruction immediately before transcatheter mitral valve replacement (TMVR). BACKGROUND: LVOT obstruction is a life-threatening complication of TMVR, caused by septal displacement of the AML. METHODS: The procedure was used in patients with severe mitral valve disease and prohibitive surgical risk...
April 24, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28427294/increased-phagocytic-nadph-oxidase-activity-associates-with-coronary-artery-calcification-in-asymptomatic-men
#16
Oscar Beloqui, María U Moreno, Gorka San José, Álvaro Pejenaute, Adriana Cortés, Manuel F Landecho, Javier Díez, Ana Fortuño, Guillermo Zalba
Vascular calcification is a common feature in atherosclerosis and associates with cardiovascular events. Oxidative stress may be involved in the pathogenesis of vascular calcification. Previous studies have shown that the phagocytic NADPH oxidase is associated with atherosclerosis. The objective of the present study was to investigate the association between phagocytic NADPH oxidase-mediated superoxide production and coronary artery calcium (CAC). NADPH oxidase-mediated superoxide production was determined by chemiluminescence and CAC by computed tomography in 159 asymptomatic men free of overt clinical atherosclerosis...
April 20, 2017: Free Radical Research
https://www.readbyqxmd.com/read/28422827/a-case-of-a-resected-benign-myxoma-like-hemorrhagic-cyst-which-later-recurred-as-undifferentiated-pleomorphic-sarcoma-in-the-left-atrium
#17
Eunju Kim, Seo-Won Choi, Daniel Min, Sang Hoon Kim, Woo-In Yang, Jae Youn Moon, Jung Hoon Sung, In Jai Kim, Sang-Wook Lim, Dong-Hun Cha, Byung Moon, Sang-Ho Cho, Won-Jang Kim
RATIONALE: An intracardiac cystic mass is a rare type of mass found in the left atrium. The differential diagnosis of an intracardiac cystic mass includes hydatid cysts, bronchogenic cysts, intracardiac varices, and hemorrhages in some tumor types, including myxoma. PATIENT CONCERNS: We present the case of a 68-year-old woman who presented with episodic dyspnea. DIAGNOSES-INTERVENTIONS-OUTCOMES: Transthoracic echocardiography (TTE) revealed the presence of a left atrial mass mimicking myxoma...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28420590/volume-and-dimensions-of-angiographically-normal-coronary-arteries-assessed-by-multidetector-computed-tomography
#18
Samuel Kiil Sørensen, Jørgen Tobias Kühl, Andreas Fuchs, Jakob Boesgaard Norsk, Lars Valeur Køber, Børge Grønne Nordestgaard, Klaus Fuglsang Kofoed
BACKGROUND: The objective of this study was to determine normal values for coronary artery volume (CAV) and individual vasculature and segment dimensions. METHODS: We examined 200 healthy volunteers with an Agatston score of 0 and a normal, high quality coronary CTA. Using 320 slice multidetector row CT and designated vessel tracing software with border detection algorithm, the main coronary arteries and branches were delineated and total and segmental dimensions calculated...
April 4, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28416984/the-inferior-displacement-of-the-his-bundle-and-fast-pathway-in-a-patient-with-common-type-atrioventricular-nodal-tachycardia-three-dimensional-computed-tomography-analysis
#19
Kunihiko Kiuchi, Koji Fukuzawa, Mori Shumpei, Tatsuya Nishii
A 66-year-old woman with palpitations was referred to our center for catheter ablation due to drug-refractory, common type atrioventricular nodal tachycardia (AVNRT). A selective slow pathway ablation was attempted. A fast junctional rhythm with transient ventriculoatrial block followed by transient prolongation of the A-H interval occurred immediately after the radiofrequency (RF) application at the coronary sinus ostium (CSOS) level. To assess the location of the fast pathway and His bundle, we sought to visualize the anatomy of the triangle of Koch (TOK) by three-dimensional computed tomography (CT)...
April 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28413187/noninvasive-fractional-flow-reserve-derived-from-coronary-computed-tomography-angiography%C3%A3-is-this-just-another-new-diagnostic-test-or-the-long-awaited-game-changer
#20
Hiromasa Otake, Charles A Taylor, Hitoshi Matsuo, Nobuhiro Tanaka, Takashi Akasaka
Despite the clinical importance of ischemia evaluation, obtaining fractional flow reserve (FFR) value has, heretofore, only been available during invasive cardiac catheterization. Although there is a clear linkage between morphology and physiology, a significant gap still exists. FFR derived from coronary computed tomography angiography (FFRCT) is a novel method of quantifying the hemodynamic significance of coronary artery stenoses by translating morphological information into hemodynamic data. Improved diagnostic performance of FFRCThas been repeatedly demonstrated in comparison with coronary computed tomography angiography alone with an invasive FFR reference standard...
April 11, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
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