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https://www.readbyqxmd.com/read/28734180/bottom-up-assembly-of-salivary-gland-microtissues-for-assessing-myoepithelial-cell-function
#1
Tugba Ozdemir, Padma Pradeepa Srinivasan, Daniel R Zakheim, Daniel A Harrington, Robert L Witt, Mary C Farach-Carson, Xinqiao Jia, Swati Pradhan-Bhatt
Myoepithelial cells are flat, stellate cells present in exocrine tissues including the salivary glands. While myoepithelial cells have been studied extensively in mammary and lacrimal gland tissues, less is known of the function of myoepithelial cells derived from human salivary glands. Several groups have isolated tumorigenic myoepithelial cells from cancer specimens, however, only one report has demonstrated isolation of normal human salivary myoepithelial cells needed for use in salivary gland tissue engineering applications...
July 14, 2017: Biomaterials
https://www.readbyqxmd.com/read/28731559/association-between-anthropometric-measures-of-regional-fat-mass-and-heart-rate-variability-in-obese-women
#2
Marina Rastović, Biljana Srdić-Galić, Oto Barak, Edita Stokić
AIM: Impaired autonomic function could be the mechanism for the development of cardiometabolic diseases in obesity. Hence, simple anthropometric measures of overall and central obesity could be screening markers for autonomic imbalance. We analysed the relationship between heart rate variability (HRV) parameters and obesity indicators. METHODS: Sixty-three obese women underwent blood pressure, lipids and anthropometric measurements, body composition assessment, HOMA (homeostasis model assessment) index calculation and short-term HRV analysis...
February 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28730326/infectious-diseases-causing-autonomic-dysfunction
#3
REVIEW
Francisco Javier Carod Artal
OBJECTIVES: To review infectious diseases that may cause autonomic dysfunction. METHODS: Review of published papers indexed in medline/embase. RESULTS: Autonomic dysfunction has been reported in retrovirus (human immunodeficiency virus (HIV), human T-lymphotropic virus), herpes viruses, flavivirus, enterovirus 71 and lyssavirus infections. Autonomic dysfunction is relatively common in HIV-infected patients and heart rate variability is reduced even in early stages of infection...
July 20, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28729675/oxygen-induced-impairment-in-arterial-function-is-corrected-by-slow-breathing-in-patients-with-type-1-diabetes
#4
Luciano Bernardi, Daniel Gordin, Marco Bordino, Milla Rosengård-Bärlund, Anna Sandelin, Carol Forsblom, Per-Henrik Groop
Hyperoxia and slow breathing acutely improve autonomic function in type-1 diabetes. However, their effects on arterial function may reveal different mechanisms, perhaps potentially useful. To test the effects of oxygen and slow breathing we measured arterial function (augmentation index, pulse wave velocity), baroreflex sensitivity (BRS) and oxygen saturation (SAT), during spontaneous and slow breathing (6 breaths/min), in normoxia and hyperoxia (5 L/min oxygen) in 91 type-1 diabetic and 40 age-matched control participants...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28727839/cardiac-autonomic-modulation-induced-by-doxorubicin-in-a-rodent-model-of-colorectal-cancer-and-the-influence-of-fullerenol-pretreatment
#5
Nejka Potočnik, Martina Perše, Anton Cerar, Rade Injac, Žarko Finderle
The very effective anticancer drug doxorubicin (DOX) is known to have cardiotoxic side effects, which could be accompanied by autonomic modulation. Autonomic disbalance might even be an initiating mechanism underlying DOX-induced cardiotoxicity and can be studied noninvasively by the analysis of heart rate variability (HRV). A number of strategies have been assessed to predict chemotherapy-induced cardiac dysfunction while HRV, a potential detecting tool, has not yet been tested. Thus, we aimed to determine the effect of DOX treatment on HRV in a rat model of colorectal cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28726661/-heart-rate-variability-in-children-with-false-chords-in-the-left-cardiac-ventricular
#6
A Kuleshov
We examined 64 children with false tendons in the left cardiac ventricular. The research included evaluation of time and frequency domain parameters of the heart rhythm with cardiointervalography. The parameter changes were noted. Thus, sympathetic vegetative system (VS) part prevalence was present in boys and characterized by decreasing of SDNN when compared with control data (85,4±5,8 и 158,2 ±25,6, р<0,05). rMSSD and PNN50%, which are responsible for parasympathetic VS part have the tendency to increasing in girls...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28725206/physiological-signal-analysis-for-evaluating-flow-during-playing-of-computer-games-of-varying-difficulty
#7
Yu Tian, Yulong Bian, Piguo Han, Peng Wang, Fengqiang Gao, Yingmin Chen
Flow is the experience of effortless attention, reduced self-consciousness, and a deep sense of control that typically occurs during the optimal performance of challenging tasks. On the basis of the person-artifact-task model, we selected computer games (tasks) with varying levels of difficulty (difficult, medium, and easy) and shyness (personality) as flow precursors to study the physiological activity of users in a flow state. Cardiac and respiratory activity and mean changes in skin conductance (SC) were measured continuously while the participants (n = 40) played the games...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28721049/the-potential-role-of-vagus-nerve-stimulation-in-the-treatment-of-hiv-associated-depression-a-review-of-literature
#8
REVIEW
William C Nicholson, Mirjam-Colette Kempf, Linda Moneyham, David E Vance
Depression is the most common comorbidity and neuropsychiatric complication in HIV. Estimates suggest that the prevalence rate for depression among HIV-infected individuals is three times that of the general population. The association between HIV and clinical depression is complex; however, chronic activation of inflammatory mechanisms, which disrupt central nervous system (CNS) function, may contribute to this association. Disruptions in CNS function can result in cognitive disorders, social withdrawal, fatigue, apathy, psychomotor impairment, and sleep disturbances, which are common manifestations in depression and HIV alike...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28721030/regular-physical-exercise-improves-cardiac-autonomic-and-muscle-vasodilatory-responses-to-isometric-exercise-in-healthy-elderly
#9
Adriana de Oliveira Sarmento, Amilton da Cruz Santos, Ivani Credidio Trombetta, Marciano Moacir Dantas, Ana Cristina Oliveira Marques, Leone Severino do Nascimento, Bruno Teixeira Barbosa, Marcelo Rodrigues Dos Santos, Maria do Amparo Andrade, Anna Myrna Jaguaribe-Lima, Maria do Socorro Brasileiro-Santos
The objective of this study was to evaluate cardiac autonomic control and muscle vasodilation response during isometric exercise in sedentary and physically active older adults. Twenty healthy participants, 10 sedentary and 10 physically active older adults, were evaluated and paired by gender, age, and body mass index. Sympathetic and parasympathetic cardiac activity (spectral and symbolic heart rate analysis) and muscle blood flow (venous occlusion plethysmography) were measured for 10 minutes at rest (baseline) and during 3 minutes of isometric handgrip exercise at 30% of the maximum voluntary contraction (sympathetic excitatory maneuver)...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28720479/interaction-between-prenatal-risk-and-infant-parasympathetic-and-sympathetic-stress-reactivity-predicts-early-aggression
#10
J Suurland, K B Van der Heijden, S C J Huijbregts, S H M Van Goozen, H Swaab
Nonreciprocal action of the parasympathetic (PNS) and sympathetic (SNS) nervous systems, increases susceptibility to emotional and behavioral problems in children exposed to adversity. Little is known about the PNS and SNS in interaction with early adversity during infancy. Yet this is when the physiological systems involved in emotion regulation are emerging and presumably most responsive to environmental influences. We examined whether parasympathetic respiratory sinus arrhythmia (RSA) and sympathetic pre-ejection period (PEP) response and recovery at six months, moderate the association between cumulative prenatal risk and physical aggression at 20 months (N=113)...
July 15, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28719973/an-exploratory-study-of-autonomic-function-investigations-in-hemophiliacs-on-homoeopathy-medications-using-impedance-plethysmography
#11
Tapas K Kundu, Pradip B Barde, Ghanshyam D Jindal, Farooq F Motiwala
BACKGROUND: Status of autonomic homoeostasis in hemostasic disturbances due to hemophilia needs to be studied. OBJECTIVES: To compare autonomic nervous system markers measured by heart rate variability (HRV) and blood flow variability (BFV) in hemophiliacs and healthy age-matched control population using medical analyzer system. DESIGN: Cross-sectional study. SETTINGS: Motiwala Homoeopathy Medical College, and Hemophilia Clinics, Nashik...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28718814/physiological-effects-of-touching-wood
#12
Harumi Ikei, Chorong Song, Yoshifumi Miyazaki
This study aimed to clarify the physiological effects of touching wood with the palm, in comparison with touching other materials on brain activity and autonomic nervous activity. Eighteen female university students (mean age, 21.7  ±  1.6 years) participated in the study. As an indicator of brain activity, oxyhemoglobin (oxy-Hb) concentrations were measured in the left/right prefrontal cortex using near-infrared time-resolved spectroscopy. Heart rate variability (HRV) was used as an indicator of autonomic nervous activity...
July 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28717299/giant-solitary-schwannoma-of-submandibular-salivary-gland-a-rare-entity
#13
Vishal Bansal, Pooja Aggarwal, Vijay Wadhwan, Avi Bansal, Sahil Kapoor, Manoj Yadav
Submandibular gland tumours, especially mesenchymal tumours, are extremely rare. Schwannoma of the salivary gland is a particularly rare form of an extracranial neurogenic tumor, of which ancient schwannoma is one of five variants. Since the first description, only a few ancient schwannomas have been reported in different locations in the head and neck region. In the submandibular gland it is very rare. This report presents a case of 26 year old male patient with an ancient schwannoma of the submandibular gland seems to be arising from parasympathetic fibers...
September 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28716723/pharmacological-characterization-of-the-interaction-between-umeclidinium-and-vilanterol-in-human-bronchi
#14
Luigino Calzetta, Paola Rogliani, Francesco Facciolo, Erino Rendina, Mario Cazzola, Maria Gabriella Matera
The long-acting β2-agonist (LABA) / long-acting muscarinic antagonist (LAMA) fixed dose combination (FDC) therapy represents the cornerstone for the treatment of chronic obstructive pulmonary disease (COPD). Nevertheless, conflicting clinical findings still exist on the real benefit of the LABA/LAMA FDCs. Therefore, we investigated whether combining the LABA vilanterol with the LAMA umeclidinium may induce synergistic bronchorelaxant effect in isolated airways. The effect of umeclidinium and vilanterol, administered alone, in combination at the ratio of concentrations reproducing the doses delivered by Anoro(®) Ellipta(®) (55:22), or at isoeffective low concentrations, was investigated on the cholinergic contractile tone induced by the parasympathetic activation of human isolated airways...
July 14, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28715786/background-lead-and-mercury-exposures-psychological-and-behavioral-problems-in-children
#15
Brooks B Gump, Matthew J Dykas, James A MacKenzie, Amy K Dumas, Bryce Hruska, Craig K Ewart, Patrick J Parsons, Christopher D Palmer, Kestutis Bendinskas
BACKGROUND: The potential harm from exposure to nonessential metals, particularly mercury (Hg) and lead (Pb), has been the focus of research for years. Initial interest focused on relatively high exposures; however, recent evidence suggests that even background exposures might have adverse consequences for child development. Identifying the extent of these consequences is now a priority. METHODS: We assessed blood Pb and Hg levels in a biracial sample of 9-11 year-old children (N = 203)...
July 14, 2017: Environmental Research
https://www.readbyqxmd.com/read/28715351/interacting-influences-of-gender-and-chronic-pain-status-on-parasympathetically-mediated-heart-rate-variability-in-adolescents-and-young-adults
#16
Lynn S Walker, Amanda L Stone, Craig A Smith, Stephen Bruehl, Judy Garber, Martina Puzanovova, André Diedrich
Considerable research links chronic pain to autonomic nervous system (ANS) dysfunction, specifically low heart rate variability (HRV) mediated by reduced parasympathetic activity. However, little is known about factors that influence ANS function in chronic pain. The ANS is the primary pathway for brain-gut communication, making it of particular interest in gastrointestinal disorders, such as irritable bowel syndrome, characterized by functional abdominal pain (FAP). We evaluated the relation of sex, pain severity, and psychological stress to ANS function in adolescents/young adults from a database of pediatric FAP and control participants enrolled 8 years earlier in a prospective study of pain...
August 2017: Pain
https://www.readbyqxmd.com/read/28715142/cholinesterase-inhibition-reduces-arrhythmias-in-asymptomatic-chagas-disease
#17
Renata Rodrigues Teixeira de Castro, Graciema Porphirio, Sergio Salles Xavier, Ruy Silveira Moraes, Elton Luis Ferlin, Jorge Pinto Ribeiro, Antonio Claudio Lucas da Nóbrega
INTRODUCTION: Parasympathetic dysfunction may play a role in the genesis of arrhythmias in Chagas disease. AIM: This study evaluates the acute effects of pyridostigmine (PYR), a reversible cholinesterase inhibitor, on the occurrence of arrhythmias in patients with Chagas cardiac disease. METHOD: Following a double-blind, randomized, placebo-controlled, cross-over protocol, 17 patients (age 50±2 years) with Chagas cardiac disease type B underwent 24-hour Holter recordings after oral administration of either pyridostigmine bromide (45 mg, 3 times/day) or placebo (PLA)...
July 17, 2017: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/28714594/neural-correlates-of-heart-rate-variability-in-ptsd-during-sub-and-supraliminal-processing-of-trauma-related-cues
#18
Daniela Rabellino, Wendy D'Andrea, Greg Siegle, Paul A Frewen, Reese Minshew, Maria Densmore, Richard W Neufeld, Jean Théberge, Margaret C McKinnon, Ruth A Lanius
BACKGROUND: Posttraumatic stress disorder (PTSD) is characterized by dysregulated arousal and altered cardiac autonomic response as evidenced by decreased high-frequency heart rate variability (HF-HRV), an indirect measure of parasympathetic modulation of the heart. Indeed, subtle threatening cues can cause autonomic dysregulation, even without explicit awareness of the triggering stimulus. Accordingly, examining the neural underpinnings associated with HF-HRV during both sub- and supraliminal exposure to trauma-related cues is critical to an enhanced understanding of autonomic nervous system dysfunction in PTSD...
July 17, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28713236/modulation-of-calcitonin-parathyroid-hormone-and-thyroid-hormone-secretion-by-electrical-stimulation-of-sympathetic-and-parasympathetic-nerves-in-anesthetized-rats
#19
Harumi Hotta, Akiko Onda, Harue Suzuki, Philip Milliken, Arun Sridhar
The thyroid and parathyroid glands are dually innervated by sympathetic (cervical sympathetic trunk [CST]) and parasympathetic (superior laryngeal nerve [SLN]) nerve fibers. We examined the effects of electrical stimulation of efferent or afferent nerve fibers innervating the thyroid and parathyroid glands on the secretion of immunoreactive calcitonin (iCT), parathyroid hormone (iPTH), 3,3',5-triiodothyronine (iT3), and thyroxine (iT4) from the thyroid and parathyroid glands. In anesthetized and artificially ventilated rats, thyroid venous blood was collected...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28713088/-pathogenic-factors-of-regulatory-mechanisms-of-organism-adaptation-to-conditions-with-a-high-level-of-psychoemotional-load
#20
Oksana V Gorsha, Vasily I Gorsha
INTRODUCTION: The urgency of the issue is determined by the value of the stress impact of environmental conditions on workers of the operator personnel contingent, because the deterioration of their health and well-being is a factor in dangerous situations. However, the search for early diagnostic markers forming diseases, with a view to their prevention, is still a challenge. The aim was to establish the most important (among studied) pathogenetic factors of status of regulatory mechanisms of adaptation of individuals with a high level of psychoemotional load that is conditional upon profession...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
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