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https://www.readbyqxmd.com/read/27912948/therapeutic-efficacy-of-traditional-chinese-medicine-kuan-sin-yin-in-patients-undergoing-chemotherapy-for-advanced-colon-cancer-a-controlled-trial
#1
Tsai-Ju Chien, Chia-Yu Liu, Ruey-Hwa Lu, Chin-Wei Kuo, Yang-Chao Lin, Chung-Hua Hsu
BACKGROUND: Traditional Chinese Medicine (TCM) has been used increasingly as complementary medicine in cancer care. Kuan-Sin-Yin (KSY) is a TCM decoction containing seven herbs known to cause immunomodulation or anticancer activity, and which are associated with the TCM concept of Qi and energy supply. Kuan-Sin-Yin has cytostatic effects on cancer cells in animal models. OBJECTIVE: The aim of this study is to evaluate the level of improvement in meridian energy and heart-rate variability (HRV) and to assess whether these observations are compatible with TCM theory...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27912864/clinical-and-epidemiological-aspects-of-scorpionism-in-the-world-a-systematic-review
#2
REVIEW
Maria S V Santos, Cláudio G L Silva, Basílio Silva Neto, Cícero R P Grangeiro Júnior, Victor H G Lopes, Antônio G Teixeira Júnior, Deryk A Bezerra, João V C P Luna, Josué B Cordeiro, Jucier Gonçalves Júnior, Marcos A P Lima
OBJECTIVE: Scorpion stings are registered worldwide, but the incidence and the features of the envenomations vary depending on the region. The aim of this review was to summarize the epidemiological, clinical, diagnostic, and therapeutic data worldwide regarding humans stung by scorpions. METHODS: A systematic review of the literature was conducted through the online databases of the Virtual Health Library (VHL), which hosts Medline and the Latin American and Caribbean Center on Health Sciences Informational (LILACS) database...
December 2016: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/27912162/serotonin-2a-receptor-5-ht2a-gene-promoter-variant-interacts-with-chronic-perceived-stress-to-modulate-resting-parasympathetic-activity-in-humans
#3
Chuan-Chia Chang, Wen-Hui Fang, Hsin-An Chang, Tieh-Ching Chang, Jia-Fwa Shyu, San-Yuan Huang
Decreased resting vagal (parasympathetic) tone is implicated in the development of stress-related disorders, including anxiety and depression. Chronic stress elevates the expression of serotonin 2A receptors (5-HT2A), while activation of 5-HT2A leads to inhibition of parasympathetic synaptic transmission. The T allele of the promoter variant, rs6311 (C>T), of the 5-HT2A gene has been shown to increase the 5-HT2A expression in vitro and to be associated with anxiety and depressive disorders. We thus hypothesized that the 5-HT2A functional polymorphism may influence resting vagal activity among persons with chronically high levels of perceived stress...
November 16, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27910248/use-of-heart-rate-variability-and-photoplethysmograph-derived-parameters-as-assessment-signals-of-radiofrequency-therapy-efficacy-for-chronic-pain
#4
Jing-Jhao Ye, Chiung-Cheng Chuang, Yu-Ting Tai, Kuan-Ting Lee, Kuo-Sheng Hung
BACKGROUND: Radiofrequency therapy (RFT) generates molecular motion, and produces heat and electromagnetic effects on tissues, which attenuate pain sensation and thereby relieve pain. This study was to observe the altering trend of physiological parameters after RFT for chronic cervical or lumbar pain. METHODS: This study recruited 66 patients with chronic cervical or lumbar pain, and recorded their physiological parameters before and after RFT by using heart rate variability (HRV) and photoplethysmography (PPG) to explore the feasibility of RFT efficacy assessment...
December 2, 2016: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/27906714/central-nervous-system-regulation-of-hepatic-lipid-and-lipoprotein-metabolism
#5
Jennifer Taher, Sarah Farr, Khosrow Adeli
PURPOSE OF REVIEW: Hepatic lipid and lipoprotein metabolism is an important determinant of fasting dyslipidemia and the development of fatty liver disease. Although endocrine factors like insulin have known effects on hepatic lipid homeostasis, emerging evidence also supports a regulatory role for the central nervous system (CNS) and neuronal networks. This review summarizes evidence implicating a bidirectional liver-brain axis in maintaining metabolic lipid homeostasis, and discusses clinical implications in insulin-resistant states...
November 30, 2016: Current Opinion in Lipidology
https://www.readbyqxmd.com/read/27905081/parasympathetic-cardio-regulation-during-social-interactions-in-individuals-with-obesity-the-influence-of-negative-body-image
#6
Anne Schrimpf, Jana Kube, Jane Neumann, Annette Horstmann, Arno Villringer, Michael Gaebler
Individuals with obesity in Western societies often face weight-related stigmatization and social exclusion. Recurrent exposure to prejudice and negative social feedback alters one's behavior in future social interactions. In this study, we aimed to investigate autonomic nervous system and affective responses to social interactions in individuals with obesity. Women and men with (n = 56) and without (n = 56) obesity participated in episodes of social inclusion and social exclusion using a virtual ball-tossing game...
November 30, 2016: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/27902931/human-presynaptic-receptors
#7
REVIEW
Eberhard Schlicker, Thomas Feuerstein
Presynaptic receptors are sites at which transmitters, locally formed mediators or hormones inhibit or facilitate the release of a given transmitter from its axon terminals. The interest in the identification of presynaptic receptors has faded in recent years and it may therefore be justified to give an overview of their occurrence in the autonomic and central nervous system; this review will focus on presynaptic receptors in human tissues. Autoreceptors are presynaptic receptors at which a given transmitter restrains its further release, though in some instances may also increase its release...
November 27, 2016: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27901339/cardiac-parasympathetic-reactivation-after-small-sided-soccer-games-and-repeated-sprints-in-untrained-healthy-adolescents
#8
Amri Hammami, Sofien Kasmi, Narimen Yousfi, Marwa Bouamra, Zouhaier Tabka, Ezdine Bouhlel
BACKGROUND: It has been shown that recreational soccer was a highly motivating and social activity which produces large improvements in health-related indices in sedentary healthy and unhealthy subjects. The purpose of this study was to compare the acute parasympathetic reactivation after small-sided soccer games (SSG) and repeated sprints training (RST) sessions. METHODS: Eight post-pubertal untrained adolescents (age 15.8 ± 0.6 years, body mass 59.1 ± 3.7 kg, height 1...
November 30, 2016: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/27900748/-effects-of-different-genres-of-music-on-the-psycho-physiological-responses-of-undergraduates
#9
Hsin-Ping Lee, Yu-Chen Liu, Mei-Feng Lin
BACKGROUND: Undergraduate students face tremendous stressors from learning, interpersonal relationships, and life. Stress may cause adaptation exhaustion and stress-related disorders. While the results of recent clinical studies indicate that music interventions may alleviate stress, there is a dearth of research exploring the discrete effects of various genres of music on psycho-physiological status. PURPOSE: To explore the effects of listening to different genres of music on the psycho-physiological responses of undergraduates...
December 2016: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/27900499/cardiac-parasympathetic-dysfunction-in-the-early-phase-of-parkinson-s-disease
#10
Masashi Suzuki, Tomohiko Nakamura, Masaaki Hirayama, Miki Ueda, Masahisa Katsuno, Gen Sobue
Cardiac parasympathetic function is strongly affected by aging. Although sympathetic dysfunction has been well documented in Parkinson's disease (PD), cardiac parasympathetic dysfunction has not been well studied. The objective of this study was to clarify the development of cardiac parasympathetic dysfunction in the early phase of PD and to explore the age-corrected correlation between cardiac parasympathetic dysfunction and cardiac sympathetic dysfunction. We reviewed 25 healthy controls and 56 patients with idiopathic PD of Hoehn and Yahr stages I-III...
November 29, 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27899438/the-impact-of-exercise-only-based-rehabilitation-on-depression-and-anxiety-in-patients-after-myocardial-infarction
#11
Iwona Korzeniowska-Kubacka, Maria Bilińska, Dorota Piotrowska, Monika Stepnowska, Ryszard Piotrowicz
AIM: The aim of the study was to assess the effectiveness of exercise training on depression, anxiety, physical capacity and sympatho-vagal balance in patients after myocardial infarction and compare differences between men and women. METHODS: Thirty-two men aged 56.3±7.6 years and 30 women aged 59.2±8.1 years following myocardial infarction underwent an 8-week training programme consisting of 24 interval trainings on cycloergometer, three times a week. Before and after completing the training programme, patients underwent: depression intensity assessment with the Beck depression inventory; anxiety assessment with the state-trait anxiety inventory; a symptom-limited exercise test during which were analysed: maximal workload, duration, double product...
November 29, 2016: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/27899232/expression-of-muscarinic-acetylcholine-receptors-in-hepatocytes-from-rat-fibrotic-liver
#12
Lin Luo, Tingting Xu, Pengbo Wang, Liuliu Mao, Chenghao Xi, Jinhua Huang, Wei Zhang
The pathological changes of parasympathetic nerve are considered as an independent prognostic factor of the survival rate of patients with chronic liver disease. The non-selective muscarinic acetylcholine receptors (mAchR) agonists and antagonists can affect the proliferation of hepatocytes and hepatic stellate cells, but the subtypes of mAchR expressions in HCs are still uncertain. Here, we investigate the expression of mAchR in hepatic fibrosis on rats. 3ml/kg 40% carbon tetrachloride (CCL4) was given to induce hepatic fibrosis on rats and the hepatocytes were isolated...
November 26, 2016: Experimental and Toxicologic Pathology: Official Journal of the Gesellschaft Für Toxikologische Pathologie
https://www.readbyqxmd.com/read/27899087/paradoxical-physiological-responses-to-propranolol-in-a-rett-syndrome-patient-a-case-report
#13
P J Santosh, L Bell, K Lievesley, J Singh, F Fiori
BACKGROUND: Rett Syndrome (RTT), caused by a loss-of-function in the epigenetic modulator: X-linked methyl-CpG binding protein 2 (MeCP2), is a pervasive neurological disorder characterized by compromised brain functions, anxiety, severe mental retardation, language and learning disabilities, repetitive stereotyped hand movements and developmental regression. An imbalance in the sympathetic and the parasympathetic nervous system (dysautonomia) and the resulting autonomic storms is a frequent occurrence in patients with RTT...
November 29, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27894750/risk-factors-for-autonomic-and-somatic-nerve-dysfunction-in-different-stages-of-glucose-tolerance
#14
Rumyana Dimova, Tsvetalina Tankova, Velina Guergueltcheva, Ivailo Tournev, Nevena Chakarova, Greta Grozeva, Lilia Dakovska
AIM: The present study evaluates autonomic and somatic nerve function in different stages of glucose tolerance and its correlation with different cardio-metabolic parameters. MATERIAL AND METHODS: Four hundred seventy-eight subjects, mean age 49.3±13.7years and mean BMI 31.0±6.2kg/m2, divided according to glucose tolerance: 130 with normal glucose tolerance (NGT), 227 with prediabetes (125 with impaired fasting glucose (IFG) and 102 with isolated impaired glucose tolerance (iIGT)), and 121 with newly-diagnosed T2D (NDT2D), were enrolled...
November 6, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27890479/heart-rate-variability-and-psychometric-responses-to-overload-and-tapering-in-collegiate-sprint-swimmers
#15
Andrew A Flatt, Bjoern Hornikel, Michael R Esco
OBJECTIVES: The purpose of this study was to evaluate cardiac-parasympathetic and psychometric responses to competition preparation in collegiate sprint-swimmers. Additionally, we aimed to determine the relationship between average vagal activity and its daily fluctuation during each training phase. DESIGN: Observational. METHODS: Ten Division-1 collegiate sprint-swimmers performed heart rate variability recordings (i.e., log transformed root mean square of successive RR intervals, lnRMSSD) and completed a brief wellness questionnaire with a smartphone application daily after waking...
November 17, 2016: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/27889103/cardiac-autonomic-changes-after-thoracic-sympathectomy-a-prospective-randomized%C3%A2-study
#16
Alfonso Fiorelli, Giovanni Messina, Paolo Chiodini, Saveria Costanzo, Andrea Viggiano, Marcellino Monda, Giovanni Vicidomini, Mario Santini
BACKGROUND: We evaluated whether cardiac autonomic changes could be associated with different extent of sympathetic nerve resection in the management of essential palmar hyperhidrosis. METHODS: Sixty patients with essential palmar hyperhidrosis were randomly allocated to undergo excision of T3 ganglia (sympathicectomy group; n = 30) or to interruption of sympathetic chain at the T2 to T3 level with ganglion sparing (sympathicotomy group; n = 30). Time and frequency domains were measured with a 24-Holter monitor during daytime, nighttime, and 24-hour periods at different interval points (7 days before operation; 24 hours; and 1, 3, and 6 months later), and the differences were statistically compared...
November 23, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27887910/assessment-of-serum-level-of-corticotropin-releasing-factor-in-primary-nocturnal-enuresis
#17
Ayat A Motawie, Amany M Abd Al-Aziz, Hanan M Hamed, Amany A A Fatouh, Mona A M Awad, Amany Abd El-Ghany
INTRODUCTION: Primary nocturnal enuresis is one of the sleep related phenomena characterized by disruption in the relationship between arousal and urination. Corticotropin-releasing factor (CRF) is a neurohormone released from the paraventricular nucleus of the hypothalamus into the median eminence to elicit release of adrenocorticotrophin from the anterior pituitary. It may act to modulate autonomic function and behavior in concert with the endocrine effects. Conflicting animal studies about the role of CRF in micturition, either facilitating or inhibiting, have been raised...
October 24, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27887781/high-psychosis-liability-is-associated-with-altered-autonomic-balance-during-exposure-to-virtual-reality-social-stressors
#18
Jacqueline Counotte, Roos Pot-Kolder, Arie M van Roon, Olivier Hoskam, Mark van der Gaag, Wim Veling
BACKGROUND: Social stressors are associated with an increased risk of psychosis. Stress sensitisation is thought to be an underlying mechanism and may be reflected in an altered autonomic stress response. Using an experimental Virtual Reality design, the autonomic stress response to social stressors was examined in participants with different liability to psychosis. METHOD: Fifty-five patients with recent onset psychotic disorder, 20 patients at ultra-high risk for psychosis, 42 siblings of patients with psychosis and 53 controls were exposed to social stressors (crowdedness, ethnic minority status and hostility) in a Virtual Reality environment...
November 22, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27885745/exaggerated-reactivity-of-parasympathetic-nerves-is-involved-in-ventricular-fibrillation-in-j-wave-syndrome
#19
Tetsuji Shinohara, Hidekazu Kondo, Toyokazu Otsubo, Akira Fukui, Kunio Yufu, Mikiko Nakagawa, Naohiko Takahashi
INTRODUCTION: Brugada syndrome (BrS) and early repolarization syndrome (ERS) are termed the J-wave syndrome. In most cases of J-wave syndrome, ventricular fibrillation (VF) often occurs around midnight or in the early morning when parasympathetic tone is augmented. OBJECTIVE: The purpose of this study was to clarify the relationship between VF and autonomic nervous activity in patients with J-wave syndrome. METHODS AND RESULTS: We enrolled 28 consecutive patients with J-wave syndrome (20 BrS and 8 ERS) in whom implantable cardioverter-defibrillators (ICDs) were implanted between January 2002 and December 2014...
November 25, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/27884045/retinoic-acid-signaling-regulates-krt5-and-krt14-independently-of-stem-cell-markers-in-submandibular-salivary-gland-epithelium
#20
Timur M Abashev, Melissa A Metzler, Diana M Wright, Lisa L Sandell
BACKGROUND: Retinoic Acid (RA), the active metabolite of Vitamin A, has been demonstrated to be important for growth and branching morphogenesis of mammalian embryonic salivary gland epithelium. However, it is not known whether RA functions directly within epithelial cells or in associated tissues that influence morphogenesis of salivary epithelium. Moreover, downstream targets of RA regulation have not been identified. RESULTS: Here we show that canonical RA signaling occurs in multiple tissues of embryonic mouse salivary glands, including epithelium, associated parasympathetic ganglion neurons, and non-neuronal mesenchyme...
November 24, 2016: Developmental Dynamics: An Official Publication of the American Association of Anatomists
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