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Vitamin d deficiency

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https://www.readbyqxmd.com/read/29046199/-association-between-serum-25-oh-d-levels-at-birth-and-bronchopulmonary-dysplasia-in-preterm-infants
#1
Ren-Qiang Yu, Dao-Zhen Chen, Qin Zhou, Min Wang, Ying-Zi Mei, Shan-Yu Jiang
OBJECTIVE: To assess the association between serum 25-hydroxyvitamin D [25(OH)D] levels at birth and bronchopulmonary dysplasia (BPD) in preterm infants. METHODS: This study recruited preterm infants with gestational age of below 34 weeks who were born between January 2014 and December 2016. These preterm infants were classified into two groups: BPD and control. The association between serum 25(OH)D levels at birth and BPD was analyzed. RESULTS: Serum 25(OH)D levels in the BPD group was significantly lower than those in the control group [(37±17 nmol/L vs 47±20 nmol/L; P<0...
October 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29044707/the-effect-of-vitamin-d-supplementation-on-bone-metabolic-markers-in-chronic-kidney-disease
#2
Ashok Kumar Yadav, Vivek Kumar, Vinod Kumar, Debasish Banerjee, Krishan Lal Gupta, Vivekanand Jha
Use of active forms of vitamin D is advocated in CKD patients for treatment of mineral bone disease because of the presumption that native forms of vitamin D would not undergo significant activation to calcitriol, the most active biological form of vitamin D. We present secondary analysis looking at bone turnover in subjects who completed the randomized, double blind, placebo controlled trial investigating the effect of cholecalciferol supplementation on vascular function in non-diabetic CKD stage G3-4 and vitamin D ≤20ng/ml [CTRI/2013/05/003648]...
October 17, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29044032/-the-relationship-between-serum-vitamin-d-levels-and-cardiovascular-risk-factors-among-icelandic-children
#3
Thorunn Hannesdottir, Hannes Hrafnkelsson, Erlingur Johannsson, Emil L Sigurdsson
OBJECTIVE: To determine the relationship between serum vitamin D levels and known cardiometabolic risk factors among healthy Icelandic children as well as study these connections independent of body mass index (BMI). METHODS: We assessed the relationship between serum 25-hydroxyvitamin D, adiposity measured as BMI and 7 cardiometabolic risk factors (high blood pressure, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, blood glucose and serum insulin)...
September 2017: Læknablađiđ
https://www.readbyqxmd.com/read/29043548/comparison-of-short-term-effectiveness-and-postoperative-complications-laparoscopic-gastric-plication-vs-laparoscopic-sleeve-gastrectomy
#4
Mohammad Talebpour, Donya Sadid, Atieh Talebpour, Amirsina Sharifi, Farzad Vaghef Davari
INTRODUCTION: Bariatric surgeries are the only effective long-term treatment in obese patients. The innovation of laparoscopic gastric plication (LGP) raised some questions about its effectiveness compared to traditionally used techniques such as laparoscopic sleeve gastrectomy (LSG). We tried to answer some of these questions. MATERIALS AND METHODS: We investigated 70 patients in a randomized clinical trial (IRCT2013123012294N5) from 2012 to 2015. Thirty-five patients were randomly assigned to each LSG or LGP group, using sealed envelope method...
October 17, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29042901/vitamin-d-and-hypertension
#5
REVIEW
Hye Yun Jeong, Kyung Mi Park, Mi Jung Lee, Dong Ho Yang, Sang Hoon Kim, So-Young Lee
Vitamin D has the pleiotropic effects in multiple organ systems, and vitamin D deficiency was suggested to be associated with high blood pressure according to previous reports. Several interventional studies have examined the effect of vitamin D supplementation on high blood pressure patients, but the results have been inconsistent. In this article, we examined the literature that have proposed a mechanism involving vitamin D in the regulation of blood pressure and review previous observational and interventional studies that have shown the relationship between vitamin D and hypertension among various populations...
September 2017: Electrolyte & Blood Pressure: E & BP
https://www.readbyqxmd.com/read/29042866/effects-of-cord-blood-vitamin-d-levels-on-the-risk-of-neonatal-sepsis-in-premature-infants
#6
Birgul Say, Nurdan Uras, Suzan Sahin, Halil Degirmencioglu, Serife Suna Oguz, Fuat Emre Canpolat
PURPOSE: Vitamin D plays a key role in immune function. Vitamin D deficiency may play a role in the pathogenesis of infections, and low levels of circulating vitamin D are strongly associated with infectious diseases. In this study, we aimed to evaluate the effects of low vitamin D levels in cord blood on neonatal sepsis in preterm infants. METHODS: One hundred seventeen premature infants with gestational age of <37 weeks were enrolled. In the present study, severe vitamin D deficiency (group 1) was defined as a 25-hydroxyvitamin D (25(OH)D) concentration <5 ng/mL; vitamin D insufficiency (group 2), 25(OH)D concentration ≥5 ng/mL and <15 ng/mL; and vitamin D sufficiency (group 3), 25(OH)D concentration ≥15 ng/mL...
August 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29042790/evaluation-of-vitamin-d-levels-in-relation-to-coronary-ct-angiographic-findings-in-an-iranian-population
#7
Maryam Moradi, Ali Foroutanfar
BACKGROUND: Vitamin D deficiency, as a predisposing factor for coronary artery disease (CAD), is a subject of increasing interest. However, its role as a risk factor has not been proven. This study aimed to investigate the relationship between serum vitamin D levels and CAD. MATERIALS AND METHODS: Using a cross-sectional design, 180 patients who were candidates for coronary computed tomography angiography (CCTA) were selected. Serum levels of vitamin D were measured and compared with the results of CCTA (including calcium score, and presence and severity of coronary artery involvement due to atherosclerotic plaques)...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29040465/the-fut2-secretor-variant-p-trp154ter-influences-serum-vitamin-b12-concentration-via-holo-haptocorrin-but-not-holo-transcobalamin-and-is-associated-with-haptocorrin-glycosylation
#8
Aneliya Velkova, Jennifer E L Diaz, Faith Pangilinan, Anne M Molloy, James L Mills, Barry Shane, Erica Sanchez, Conal Cunningham, Helen McNulty, Cheryl D Cropp, Joan E Bailey-Wilson, Alexander F Wilson, Lawrence C Brody
Vitamin B12 deficiency is common in older individuals. Circulating vitamin B12 concentration can be used to diagnose deficiency but this test has substantial false positive and false negative rates. We conducted genome-wide association studies (GWAS) in which we resolved total serum vitamin B12 into the fractions bound to transcobalamin and haptocorrin: two carrier proteins with very different biological properties. We replicated reported associations between total circulating vitamin B12 concentrations and a common null variant in FUT2...
October 12, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/29040128/single-dose-preoperative-vitamin-d-supplementation-decreases-infection-in-a-mouse-model-of-periprosthetic-joint-infection
#9
Vishal Hegde, Erik M Dworsky, Alexandra I Stavrakis, Amanda H Loftin, Stephen D Zoller, Howard Y Park, Sherif Richman, Daniel Johansen, Yan Hu, Julie A Taylor, Christopher D Hamad, Rene F Chun, Weixian Xi, John S Adams, Nicholas M Bernthal
BACKGROUND: Despite recent advances, infection remains the most common etiology of arthroplasty failure. Recent work suggests that 25-hydroxyvitamin D (25D) deficiency correlates with the frequency of periprosthetic joint infection (PJI). We endeavored to examine whether 25D3 deficiency leads to increased bacterial burden in vivo in an established mouse model of PJI and, if so, whether this effect can be reversed by preoperative 25D3 supplementation. METHODS: Mice (lys-EGFP) possessing fluorescent neutrophils were fed a vitamin D3-sufficient (n = 20) or deficient (n = 40) diet for 6 weeks...
October 18, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29037932/retinoic-acid-deficiency-leads-to-an-increase-in-spermatogonial-stem-number-in-the-neonatal-mouse-testis-but-excess-retinoic-acid-results-in-no-change
#10
Kellie S Agrimson, Melissa J Oatley, Debra Mitchell, Jon M Oatley, Michael D Griswold, Cathryn A Hogarth
The onset of spermatogenesis occurs in response to retinoic acid (RA), the active metabolite of vitamin A. However, whether RA plays any role during establishment of the spermatogonial stem cell (SSC) pool is unknown. Because designation of the SSC population and the onset of RA signaling in the testis that induces differentiation have similar timing, this study asked whether RA influenced SSC establishment. Whole mount immunofluorescence and flow cytometric analysis using the Id4-eGfp transgenic reporter mouse line revealed an enrichment for ID4-EGFP+ cells within the testis following inhibition of RA synthesis by WIN 18,446 treatment...
October 13, 2017: Developmental Biology
https://www.readbyqxmd.com/read/29037825/vitamin-d-prevents-lipid-accumulation-in-murine-muscle-through-regulation-of-ppar%C3%AE-and-perilipin-2-expression
#11
Jiarong Li, Milton Mihalcioiu, Lifeng Li, Mahvash Zakikhani, Anne Camirand, Richard Kremer
Vitamin D plays an important role in regulation of skeletal muscle tone and contraction. Serum vitamin D status is linked to muscle power and force in adolescent girls, and vitamin D deficiency is associated with myopathies in children and poorer physical performance in the elderly. We previously reported that vitamin D deficiency is linked to a significant increase in muscle fatty infiltration in healthy young women, and studies in patients with neuromuscular disorders also associate muscle weakening and lipid content...
October 13, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29037317/effect-of-vitamin-d-supplementation-on-patients-with-systemic-lupus-erythematosus-a-systematic-review
#12
REVIEW
Joyce Ramalho Sousa, Érica Patrícia Cunha Rosa, Ivone Freires de Oliveira Costa Nunes, Cecilia Maria Resende Gonçalves de Carvalho
The objective of this systematic review was to analyze clinical trials carried out for the investigation of the effect of vitamin D supplementation on systemic lupus erythematosus. The research was performed from August to September 2016, without limits regarding year of publication, restriction of gender, age, and ethnicity. For the guiding question, the PICO strategy was employed. To evaluate the quality of the publications the PRISMA protocol and Jadad scale were used. The risk of bias analysis of the clinical trials was performed using the Cochrane collaboration tool...
September 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/29036551/comparative-study-of-the-growth-and-nutritional-status-of-brazilian-and-nigerian-school-aged-children-with-sickle-cell-disease
#13
Samuel A Adegoke, Maria S Figueiredo, Adekunle D Adekile, Josefina A P Braga
Background: Comparative studies of patients in different sociogeographic/ecological zones may unravel potential environmental and nutritional factors influencing disease phenotype. In sickle cell disease (SCD), differential access to comprehensive care may influence their growth and nutritional status. Methods: From June 2015 to February 2016, steady-state nutritional parameters of 109 Brazilian and 95 Nigerian children with SCD attending routine clinic visits at Universidade Federal de São Paulo, Brazil and Obafemi Awolowo University Teaching Hospital, Ile-Ife (Ilesa unit), respectively, were compared...
September 28, 2017: International Health
https://www.readbyqxmd.com/read/29035877/association-of-maternal-serum-25-hydroxyvitamin-d-concentrations-with-risk-of-gestational-anemia
#14
Yingdi Yuan, Zhiyong Cai, YaoYao Dai, Qin Hong, Xingyun Wang, Lijun Zhu, Pengfei Xu, Lianghui You, Xing Wang, Chenbo Ji, Juan Wen, Xirong Guo
BACKGROUND/AIMS: Vitamin D deficiency has been shown to be associated with a greater prevalence of anemia in various healthy and diseased populations by a great deal of observational studies. However, less work has been done to explore this association in pregnant women. The aim of this study was to evaluate the association between maternal serum 25-hydroxyvitamin D [25(OH)D] concentrations and risk of gestational anemia in a large, nested case-control study. METHODS: The serum 25(OH)D concentrations was measured by enzyme immunoassay in 775 pregnant women affected with anemia and 1550 controls...
October 16, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29035301/exploring-knowledge-and-attitudes-about-vitamin-d-among-adults-in-saudi-arabia-a-qualitative-study
#15
Najlaa Aljefree, Patricia Lee, Faruk Ahmed
Abstract: Vitamin D deficiency is widespread in Saudi Arabia. The aim of this study was to explore participants' knowledge about vitamin D and attitudes toward sun exposure. The study also aimed to explore the social and cultural factors that might potentially contribute to vitamin D deficiency in Saudi Arabia. Face-to-face interviews were carried out in the cities of Jeddah and Makkah between May and October 2015. The interview questions were semi-structured, and the data was analyzed using thematic analysis...
October 16, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29035092/vitamin-d-supplementation-and-non-alcoholic-fatty-liver-disease-a-critical-and-systematic-review-of-clinical-trials
#16
Nasrin Sharifi, Reza Amani
Previous observational studies have found a relationship between vitamin D deficiency and non-alcoholic fatty liver disease (NAFLD). However, this type of study could not show the causal relationship between these two conditions. Therefore, we systematically and critically reviewed the available clinical trials to elucidate such relationship. We searched databases such as Medline, Scopus and Cochrane to identify the clinical trials that assessed the effects of vitamin D supplementation in adults with NAFLD...
October 16, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29031688/vitamin-d-deficiency-is-associated-with-poor-breast-cancer-prognostic-features-in-postmenopausal-women
#17
Benedito de Sousa Almeida-Filho, Heloisa De Luca Vespoli, Eduardo Carvalho Pessoa, Murilo Machado, Jorge Nahas-Neto, Eliana Aguiar Petri Nahas
This study aimed to evaluate the association between pretreatment vitamin D (VD) deficiency with breast cancer prognostic features in Brazilian postmenopausal women. An analytical cross sectional study was conducted with 192 women, aged 45-75 years, attended at University Hospital. Women with recent diagnosis of breast cancer, in amenorrhea >12months and age ≥45 years, without medication use or clinical conditions that interfere with VD values were included. Clinical and anthropometric data were collected...
October 11, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29030989/genetic-and-epigenetic-factors-influencing-vitamin-d-status
#18
REVIEW
Afsane Bahrami, Hamid Reza Sadeghnia, Seyed-Amir Tabatabaeizadeh, Hamidreza Bahrami-Taghanaki, Negin Behboodi, Habibollah Esmaeili, Gordon A Ferns, Majid Ghayour Mobarhan, Amir Avan
The global prevalence of vitamin D deficiency appears to be increasing, and the impact of this on human health is important because of the association of vitamin D insufficiency with increased risk of osteoporosis, cardiovascular disease and some cancers. There are few studies on the genetic factors that can influence vitamin D levels. In particular, the data from twin and family-based studies have reported that circulating vitamin D concentrations are partially determined by genetic factors. Moreover, it has been shown that genetic variants (e...
October 14, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29029097/impact-of-three-doses-of-vitamin-d3-on-serum-25-oh-d-deficiency-and-insufficiency-in-at-risk-schoolchildren
#19
Jennifer M Sacheck, Maria I Van Rompay, Virginia R Chomitz, Christina D Economos, Misha Eliasziw, Elizabeth Goodman, Catherine M Gordon, Michael F Holick
Objective: We investigated the daily dose of vitamin D needed to achieve serum 25-hydroxyvitamin D [25(OH)D] sufficiency among schoolchildren at-risk for deficiency. Study Design: The Daily D Health Study was a randomized double-blind vitamin D supplementation trial among racially/ethnically diverse schoolchildren (n=685) in the northeastern U.S. Children were supplemented with vitamin D3 at 600, 1000, or 2000 IU/day for six months. Measurements included serum 25(OH)D at baseline (Oct-Dec), 3 months (Jan-March), 6 months (April-June), and 12 months (6 months post-supplementation)...
September 27, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29027953/vitamin-d-and-age-related-macular-degeneration
#20
REVIEW
Alfredo Garcia Layana, Angelo Maria Minnella, Gerhard Garhöfer, Tariq Aslam, Frank G Holz, Anita Leys, Rufino Silva, Cécile Delcourt, Eric Souied, Johanna M Seddon
In recent years, the relationship between vitamin D and health has received growing attention from the scientific and medical communities. Vitamin D deficiencies have been repeatedly associated with various acute and chronic diseases, including age-related macular degeneration (AMD). Its active metabolite, 1α,25-dihydoxy vitamin D, acts as a modulator of cell proliferation, differentiation and apoptosis, and cumulative data from experimental and observational studies suggest that relatively a lower vitamin D status could be a potential risk factor for the development of early and/or late AMD...
October 13, 2017: Nutrients
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