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https://www.readbyqxmd.com/read/29730974/effect-of-breathing-type-on-electromyographic-activity-of-respiratory-muscles-during-tooth-clenching-at-different-decubitus-positions
#1
Rodolfo Miralles, Natalia Andrea Gamboa, Mario Felipe Gutiérrez, Hugo Santander, Saúl Valenzuela, Ricardo Bull, Aler Daniel Fuentes, Rosa Córdova
Objective To compare the effect of breathing type on electromyographic (EMG) activity of respiratory muscles during tooth clenching at different decubitus positions. Methods Forty young men participants were included, 11 with upper costal, 9 with mixed, and 20 with costo-diaphragmatic breathing type. EMG recordings of diaphragm (DIA), external intercostal (EIC), sternocleidomastoid (SCM), and latissimus dorsi (LAT) muscles during tooth clenching in the intercuspal position were performed in dorsal, left lateral, and ventral decubitus positions...
May 7, 2018: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29725734/analysis-of-isocyanates-in-indoor-dust
#2
Kanae Bekki, Shigehisa Uchiyama, Naoki Kunugita
Isocyanates are harmful semi-volatile organic compounds that are emitted from various consumer products like polyurethane foam-based mattresses. Although it is a concern that isocyanates might accumulate in indoor dust, causing infants and toddlers, in particular, to be exposed to them, little information is available on the levels of isocyanates in the indoor environment. In this study, we investigated the suitability of an analytical method for determining the presence and level of isocyanates in the indoor dust...
May 4, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29695022/catheter-related-arterial-thrombosis-in-neonates-and-children-a-systematic-review
#3
Mattia Rizzi, Neil Goldenberg, Mariana Bonduel, Shoshana Revel-Vilk, Ernest Amankwah, Manuela Albisetti
Catheter-related arterial thrombosis (CAT) is increasingly recognized in children. Available data are scarce and based on expert opinions. This systematic review aimed to identify knowledge on paediatric CAT. Among 3,484 publications, 22 met inclusion criteria. Fourteen reported on CAT due to umbilical arterial catheter (UAC), two to extremity indwelling catheter (EIC), one to both and five to cardiac catheter (CC). The overall cumulative incidence of CAT was 21% (95% confidence interval [CI], 13-31) with a relative incidence of 20% (95% CI, 10-33) for UAC and 11% (95% CI, 3-21) for CC-related CAT...
April 25, 2018: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29674072/extended-internal-standard-method-for-quantitative-1-h-nmr-assisted-by-chromatography-eic-for-analyte-overlapping-impurity-on-1-h-nmr-spectra
#4
Naoki Saito, Yuko Kitamaki, Satoko Otsuka, Noriko Yamanaka, Yuzo Nishizaki, Naoki Sugimoto, Hisanori Imura, Toshihide Ihara
We devised a novel extended internal standard method of quantitative 1 H NMR (qNMR) assisted by chromatography (EIC) that accurately quantifies 1 H signal areas of analytes, even when the chemical shifts of the impurity and analyte signals overlap completely. When impurity and analyte signals overlap in the 1 H NMR spectrum but can be separated in a chromatogram, the response ratio of the impurity and an internal standard (IS) can be obtained from the chromatogram. If the response ratio can be converted into the 1 H signal area ratio of the impurity and the IS, the 1 H signal area of the analyte can be evaluated accurately by mathematically correcting the contributions of the 1 H signal area of the impurity overlapping the analyte in the 1 H NMR spectrum...
July 1, 2018: Talanta
https://www.readbyqxmd.com/read/29669755/zinc-finger-irf-composite-elements-bound-by-ikaros-irf4-complexes-function-as-gene-repression-in-plasma-cell
#5
Kyoko Ochiai, Haruka Kondo, Yasunobu Okamura, Hiroki Shima, Yuko Kurokochi, Kazumi Kimura, Ryo Funayama, Takeshi Nagashima, Keiko Nakayama, Katsuyuki Yui, Kengo Kinoshita, Kazuhiko Igarashi
The transcription factor (TF) interferon regulatory factor-4 (IRF4) promotes both germinal center (GC) reactions and plasma cell (PC) differentiation by binding to alternative DNA motifs including AP-1-IRF composite elements, Ets-IRF composite elements (EICEs), and interferon sequence response elements (ISREs). Although all of these motifs mediate transcriptional activation by IRF4, it is still unknown how some of the IRF4 target genes are downregulated upon PC differentiation. Here, we revealed a molecular mechanism of IRF4-mediated gene downregulation during PC differentiation...
April 24, 2018: Blood Advances
https://www.readbyqxmd.com/read/29659066/a-mass-spectrometry-based-predictive-strategy-reveals-adap1-is-phosphorylated-at-tyrosine-364
#6
Richard Reisdorph, BobbiJo Littrell-Miller, Roger Powell, Nichole Reisdorph
RATIONALE: The goal of this work was to identify phosphorylation sites within the amino acid sequence of human ADAP1. Using traditional mass spectrometry-based techniques we were unable to produce interpretable spectra demonstrating modification by phosphorylation. This prompted us to employ a strategy in which phosphorylated peptides were first predicted using peptide mapping followed by targeted MS/MS acquisition. METHODS: ADAP1 was immunoprecipitated from extracts of HEK293 cells stably-transfected with ADAP1 cDNA...
April 16, 2018: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/29593494/antiepileptogenic-effect-of-subchronic-palmitoylethanolamide-treatment-in-a-mouse-model-of-acute-epilepsy
#7
Julia M Post, Sebastian Loch, Raissa Lerner, Floortje Remmers, Ermelinda Lomazzo, Beat Lutz, Laura Bindila
Research on the antiepileptic effects of (endo-)cannabinoids has remarkably progressed in the years following the discovery of fundamental role of the endocannabinoid (eCB) system in controlling neural excitability. Moreover, an increasing number of well-documented cases of epilepsy patients exhibiting multi-drug resistance report beneficial effects of cannabis use. Pre-clinical and clinical research has increasingly focused on the antiepileptic effectiveness of exogenous administration of cannabinoids and/or pharmacologically induced increase of eCBs such as anandamide (also known as arachidonoylethanolamide [AEA])...
2018: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29552539/congenital-epidermal-inclusion-cyst-on-the-breast-a-case-series-of-a-rare-entity
#8
Ashish Amrani, Priyadarshini Sahu, Surabhi Dayal, Poonam Verma
Epidermal inclusion cysts (EICs) are the most common cutaneous cysts, occurring anywhere in the body but infrequently on the breast. It is usually seen in the third and fourth decades of life and very rarely seen in children. They can be either congenital or posttraumatic. Most of the EICs described in children were secondary to trauma. Congenital EIC on the breast is quite a rare entity. Thus, we herein describe two cases of congenital EIC on the breast in two infants of 3 months and 9 months of age, which to the best of our knowledge has not been reported previously...
January 2018: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29546982/impact-of-electrodes-on-recombination-in-bulk-heterojunction-organic-solar-cells
#9
Azadeh Rahimi Chatri, Solmaz Torabi, Vincent M Le Corre, L Jan Anton Koster
In recent years, the efficiency of organic solar cells (OSCs) has increased to more than 13%, although different barriers are on the way for reaching higher efficiencies. One crucial barrier is the recombination of charge carriers, which can either occur as the bulk recombination of photogenerated charges or the recombination of photogenerated charges and electrodic induced charges (EICs). This work studies the impact of EICs on the recombination lifetime in OSCs. To this end, the net recombination lifetime of photogenerated charge carriers in the presence of EICs is measured by means of conventional and newly developed transient photovoltage techniques...
April 11, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29546509/robust-eeg-meg-based-functional-connectivity-with-the-envelope-of-the-imaginary-coherence-sensor-space-analysis
#10
Jose M Sanchez Bornot, KongFatt Wong-Lin, Alwani Liyana Ahmad, Girijesh Prasad
The brain's functional connectivity (FC) estimated at sensor level from electromagnetic (EEG/MEG) signals can provide quick and useful information towards understanding cognition and brain disorders. Volume conduction (VC) is a fundamental issue in FC analysis due to the effects of instantaneous correlations. FC methods based on the imaginary part of the coherence (iCOH) of any two signals are readily robust to VC effects, but neglecting the real part of the coherence leads to negligible FC when the processes are truly connected but with zero or π-phase (modulus 2π) interaction...
March 15, 2018: Brain Topography
https://www.readbyqxmd.com/read/29521704/evaluating-the-athlete-with-suspected-exercise-induced-asthma-or-bronchospasm
#11
Fred H Brennan, Jeffrey Alent, Michael J Ross
Exercise-induced asthma (EIA) and exercise-induced bronchospasm (EIB)/bronchoconstriction (EIC) describes two clinical entities by which exercise triggers bronchial hyperresponsiveness. Exercise is a common trigger of bronchospasm in the asthmatic (EIA), as well as athletes without the underlying inflammation associated with asthma (EIC/EIB). Approximately 10% to 20% of the general population have EIA or EIB (). The approach to the diagnosis and subsequent management relies on the clinician's ability to recognize clinical signs and symptoms, then selecting the correct diagnostic test...
March 2018: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/29499095/retraction
#12
(no author information available yet)
'Influence of genetic variants of IDH1, IDH2, TET2 and DNMT3A on cytarabine cytotoxicity in different populations' by Y. Wang & J. K. Lamba1 The above article from the Journal of Clinical Pharmacy and Therapeutics, published online on 21 November 2017 in Wiley Online Library (wileyonlinelibrary.com), has been retracted following discussions with the authors, the Journal Editors and John Wiley & Sons Ltd. The Retraction has been agreed as this paper was submitted under the joint names of Yan Wang, Jatinder K...
April 2018: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29489691/preliminary-study-of-time-maximum-intensity-projection-computed-tomography-imaging-for-the-detection-of-early-ischemic-change-in-patient-with-acute-ischemic-stroke
#13
Kazuhiro Murayama, Shigetaka Suzuki, Ryo Matsukiyo, Akinori Takenaka, Motoharu Hayakawa, Takashi Tsutsumi, Kenji Fujii, Kazuhiro Katada, Hiroshi Toyama
Noncontrast computed tomography (NCCT) has been used for the detection of early ischemic change (EIC); however, correct interpretation of NCCT findings requires much clinical experience. This study aimed to assess the accuracy of time maximum intensity projection computed tomography technique (tMIP), which reflects the maximum value for the time phase direction from the dynamic volume data for each projected plane, for detection of EIC, against that of NCCT.Retrospective review of NCCT, cerebral blood volume in CT perfusion (CTP-CBV), and tMIP of 186 lesions from 280 regions evaluated by Alberta Stroke Program Early CT Score (ASPECTS) in 14 patients with acute middle cerebral artery stroke who had undergone whole-brain CTP using 320-row area detector CT was performed...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29455731/rapid-screening-and-identification-of-sesquiterpene-lactones-in-kudiezi-injection-based-on-high-performance-liquid-chromatography-coupled-with-linear-ion-trap-orbitrap-mass-spectrometry
#14
Rong-Rong Liu, Xiu-Ping Zhang, Fang Wang, Zhan-Peng Shang, Fei Wang, Ying Liu, Jian-Qiu Lu, Jia-Yu Zhang
Sesquiterpene lactones are considered as the major active compounds in Kudiezi injection in virtue of their special structures and activities. Herein, an analytical method was developed for rapid screening and identification of sesquiterpene lactones in Kudiezi injection using high-performance liquid chromatography coupled with linear ion trap-orbitrap mass spectrometry (HPLC-LTQ-Orbitrap) in negative ion mode. First, two sesquiterpene lactone reference standards were analyzed to obtain their characteristic ESI-MS/MS fragmentation patterns...
February 2018: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/29411796/the-gelation-influence-on-diffusion-and-conductivity-enhancement-effect-in-renewable-ionic-gels-based-on-a-lmwg
#15
M Bielejewski, A Rachocki, J Kaszyńska, J Tritt-Goc
This paper reports the interdisciplinary study on molecular dynamics, ionic interactions and electrical conductivity in a quaternary ammonium salt (TMABr) ionogel based on a low molecular weight gelator (LMWG) in a wide range of electrolyte molar concentrations. The thermal scanning conductometry (TSC) was used to investigate the electric properties of the ionogels. The prepared TMABr/H2 O/LMWG ionogel exhibits better ion transport properties than the dissociated TMA+ cation in solution. The enhanced ionic conductivity effect (EICE) was observed in the concentration range of the TMABr salt up to 1 M...
February 21, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29344751/associations-between-early-intervention-home-visits-family-relationships-and-competence-for-mothers-of-children-with-developmental-disabilities
#16
Morgan K Crossman, Marji Erickson Warfield, Milton Kotelchuck, Penny Hauser-Cram, Susan L Parish
Objectives To examine the association between intensity of home visits in early intervention (EI), perceived helpfulness of home visits in EI, and positive family relationships as predictors of maternal competence at age 3, as well as moderating effects of predictors, controlling for child characteristics, family demographics, and negative life events. Methods Data were drawn from the Early Intervention Collaborative Study (EICS), a 24-year longitudinal investigation of approximately 190 families of children with developmental disabilities who participated in EI programs in Massachusetts and New Hampshire...
January 17, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29305050/intraspinal-microstimulation-for-respiratory-muscle-activation
#17
Michael D Sunshine, Comron N Ganji, Paul J Reier, David D Fuller, Chet T Moritz
A complex propriospinal network is synaptically coupled to phrenic and intercostal motoneurons, and this makes it difficult to predict how gray matter intraspinal microstimulation (ISMS) will recruit respiratory motor units. We therefore mapped the cervical and high thoracic gray matter at locations which ISMS activates diaphragm (DIA) and external intercostal (EIC) motor units. Respiratory muscle electromyography (EMG) was recorded in anesthetized female spinally intact adult rats while a stimulating electrode was advanced ventrally into the spinal cord in 600μm increments...
April 2018: Experimental Neurology
https://www.readbyqxmd.com/read/29064000/-1-h-15-n-13-c-backbone-resonance-assignment-of-the-c-terminal-domain-of-enzyme-i-from-thermoanaerobacter-tengcongensis
#18
Rochelle Rea Dotas, Vincenzo Venditti
Phosphoenolpyruvate binding to the C-terminal domain (EIC) of enzyme I of the bacterial phosphotransferase system (PTS) initiates a phosphorylation cascade that results in sugar translocation across the cell membrane and controls a large number of essential pathways in bacterial metabolism. EIC undergoes an expanded to compact conformational equilibrium that is regulated by ligand binding and determines the phosphorylation state of the overall PTS. Here, we report the backbone (1)H, (15)N and (13)C chemical shift assignments of the 70 kDa EIC dimer from the thermophilic bacterium Thermoanaerobacter tengcongensis...
October 24, 2017: Biomolecular NMR Assignments
https://www.readbyqxmd.com/read/29056361/compensatory-plasticity-in-diaphragm-and-intercostal-muscle-utilization-in-a-rat-model-of-als
#19
Yasin B Seven, Nicole L Nichols, Mia N Kelly, Orinda R Hobson, Irawan Satriotomo, Gordon S Mitchell
In SOD1G93A transgenic rat model of ALS, breathing capacity is preserved until late in disease progression despite profound respiratory motor neuron (MN) cell death. To explore mechanisms preserving breathing capacity, we assessed inspiratory EMG activity in diaphragm and external intercostal T2 (EIC2) and T5 (EIC5) muscles in anesthetized SOD1G93A rats at disease end-stage (20% decrease in body mass). We hypothesized that despite significant phrenic motor neuron loss and decreased phrenic nerve activity, diaphragm electrical activity and trans-diaphragmatic pressure (Pdi) are maintained to sustain ventilation...
January 2018: Experimental Neurology
https://www.readbyqxmd.com/read/28938737/complex-catsper-dependent-and-independent-ca2-i-signalling-in-human-spermatozoa-induced-by-follicular-fluid
#20
Sean G Brown, Sarah Costello, Mark C Kelly, Mythili Ramalingam, Ellen Drew, Stephen J Publicover, Christopher L R Barratt, Sarah Martins Da Silva
STUDY QUESTION: Does progesterone in human follicular fluid (hFF) activate CatSper and do other components of hFF modulate this effect and/or contribute separately to hFF-induced Ca2+ signaling? SUMMARY ANSWER: hFF potently stimulates CatSper and increases [Ca2+]i, primarily due to high concentrations of progesterone, however, other components of hFF also contribute to [Ca2+]i signaling, including modulation of CatSper channel activity and inhibition of [Ca2+]i oscillations...
October 1, 2017: Human Reproduction
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