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https://www.readbyqxmd.com/read/29026757/socio-clinical-profile-of-married-women-with-history-of-induced-abortion-a-community-based-cross-sectional-study-in-a-rural-area
#1
Sumitra Pattanaik, Lipilekha Patnaik, Arpita Subhadarshini, Trilochan Sahu
BACKGROUND: Induced abortion contributes significantly to maternal mortality in developing countries yet women still seek repeat induced abortion in spite of the availability of contraceptive services. OBJECTIVES: (1) To study the sociodemographic profile of abortion seekers. (2) To study the reasons for procuring abortions by married women of reproductive age group. MATERIALS AND METHODS: It was a cross-sectional community-based study. All the married women of reproductive age group (15-49 years) with a history of induced abortion were selected as the subjects...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29024479/partite-hallux-sesamoid-bones-relationship-with-sesamoid-bones-at-other-metatarsophalangeal-joints
#2
Tao Sun, Haitao Zhao, Lingxiang Wang, Wenjuan Wu
Introduction - Partite hallux sesamoids are clinically meaningful but their association with other sesamoids is not clear. The objective was to relate the prevalence of the partite hallux sesamoid bones to sesamoid bones at other metatarsophalangeal (MTP) joints. Methods - We conducted a retrospective review of plain radiographs of 7946 adult feet between November 2005 and September 2012 in order to identify partite hallux sesamoids and sesamoids at other MTP joints. Coexistence patterns of the partition and extra sesamoids were studied...
October 10, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29017765/accuracy-of-shock-index-versus-abc-score-to-predict-need-for-massive-transfusion-in-trauma-patients
#3
Rebecca Schroll, David Swift, Danielle Tatum, Stuart Couch, Jiselle B Heaney, Monica Llado-Farrulla, Shana Zucker, Frances Gill, Griffin Brown, Nicholas Buffin, Juan Duchesne
BACKGROUND: Various scoring systems have been developed to predict need for massive transfusion in traumatically injured patients. Assessments of Blood Consumption (ABC) score and Shock Index (SI) have been shown to be reliable predictors for Massive Transfusion Protocol (MTP) activation. However, no study has directly compared these two scoring systems to determine which is a better predictor for MTP activation. The primary objective was to determine whether ABC or SI better predicted the need for MTP in adult trauma patients with severe hemorrhage...
September 15, 2017: Injury
https://www.readbyqxmd.com/read/29016630/association-between-kidney-function-and-genetic-polymorphisms-in-atherosclerotic-and-chronic-kidney-diseases-a-cross-sectional-study-in-japanese-male-workers
#4
Yoko Kubo, Takahiro Imaizumi, Masahiko Ando, Masahiro Nakatochi, Yoshinari Yasuda, Hiroyuki Honda, Yachiyo Kuwatsuka, Sawako Kato, Kyoko Kikuchi, Takaaki Kondo, Masamitsu Iwata, Toru Nakashima, Hiroshi Yasui, Hideki Takamatsu, Hiroshi Okajima, Yasuko Yoshida, Shoichi Maruyama
BACKGROUND: Several single nucleotide polymorphisms (SNPs) have been implicated in the predisposition to chronic kidney disease (CKD). Atherosclerotic disease is deeply involved in the incidence of CKD; however, whether SNPs related to arteriosclerosis are involved in CKD remains unclear. This study aimed to identify SNPs associated with CKD and to examine whether risk allele accumulation is associated with CKD. METHODS: We conducted a cross-sectional study using data of 4814 male workers to examine the association between estimated glomerular filtration rate (eGFR) and 59 candidate polymorphisms (17 CKD, 42 atherosclerotic diseases)...
2017: PloS One
https://www.readbyqxmd.com/read/28992936/-short-term-exercise-based-cardiac-rehabilitation-induced-changes-in-cardiorespiratory-mechanical-and-neuromuscular-responses-to-progressive-exercise-testing
#5
P-M Leprêtre, M Ghannem, S Delanaud, N Jaunet, L Gaillard, A Barnabé, T Porcher, T Weissland
Previous studies showed that changes in peak of oxygen uptake value (VO2peak) with training were poorly related to changes in Maximal Tolerated Power output (MTP) among patients with cardiovascular disease. This result could be due to a difference between cardiopulmonary adaptation to training and the skeletal muscle conditioning. OBJECTIVE: The aim of the study was to compare the responses to exercise training of electromyographic activities of vastus lateralis (rms-EMG) and respiratory parameters...
October 6, 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/28992721/correlation-of-hallux-rigidus-grade-with-motion-vas-pain-intraoperative-cartilage-loss-and-treatment-success-for-first-mtp-joint-arthrodesis-and-synthetic-cartilage-implant
#6
Judith F Baumhauer, Dishan Singh, Mark Glazebrook, Chris M Blundell, Gwyneth De Vries, Ian L D Le, Dominic Nielsen, M Elizabeth Pedersen, Anthony Sakellariou, Matthew Solan, Guy Wansbrough, Alastair S E Younger, Timothy R Daniels
BACKGROUND: Grading systems are used to assess severity of any condition and as an aid in guiding treatment. This study examined the relationship of baseline motion, pain, and observed intraoperative cartilage loss with hallux rigidus grade. METHODS: A prospective, randomized study examining outcomes of arthrodesis compared to synthetic cartilage implant was performed. Patients underwent preoperative clinical examination, radiographic assessment, hallux rigidus grade assignment, and intraoperative assessment of cartilage loss...
October 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28988307/effects-of-normoxic-and-hypoxic-exercise-regimens-on-lymphocyte-apoptosis-induced-by-oxidative-stress-in-sedentary-males
#7
Jong-Shyan Wang, Yi-Ching Chen, Wan-Ling Chen, Chin-Pu Lin
PURPOSE: Oxidative stress-induced lymphocyte apoptosis is linked to hypoxemic individuals suffering from cardiopulmonary disorders or exposed to hypoxic environments. What kind of the exercise strategy under hypoxic condition improves exercise performance and simultaneously minimizes lymphocyte dysfunction caused by oxidative stress has not yet been established. This study elucidates how various exercises regimens with/without hypoxia affect lymphocyte apoptosis induced by oxidative stress...
October 7, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28969210/prevention-of-parent-to-child-transmission-of-hiv-single-centre-experience-of-14-years-at-tertiary-care-hospital-in-delhi-india
#8
A G Radhika, Sonia Chawla, Sruthi Bhaskaran
INTRODUCTION: Prevention of Parent To Child Transmission (PPTCT) of HIV/AIDS is an integral component of AIDS control programme. PPTCT is an ongoing programme since last 15 years. AIM: The aim of the study was to evaluate the reduction in the burden of disease in newborn and infants by prevention of parents to child transmission of HIV/AIDS. MATERIALS AND METHODS: This retrospective study was conducted at Department of Obstetrics and Gynecology in a tertiary care hospital of Delhi from May 2002 to May 2015...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28964708/ldl-apheresis-in-japan
#9
REVIEW
Hisashi Makino, Tamiko Tamanaha, Mariko Harada-Shiba
LDL apheresis has been developed as the treatment for refractory familial hypercholesterolemia (FH). Currently, plasma exchange, double membrane filtration, and selective LDL adsorption are available in Japan, and selective LDL adsorption is most common method. LDL apheresis can prevent atherosclerosis progression even in homozygous (HoFH). However, in our observational study, HoFH who started LDL apheresis from adulthood had poor prognosis compared with patients who started from childhood. Therefore, as far as possible, HoFH patients need to start LDL apheresis from childhood...
August 31, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28957551/using-a-reference-when-defining-an-abnormal-mri-reduces-false-positive-mri-results-a-longitudinal-study-in-two-cohorts-at-risk-for-rheumatoid-arthritis
#10
Aleid C Boer, Leonie E Burgers, Lukas Mangnus, Robin M Ten Brinck, Wouter P Nieuwenhuis, Hanna W van Steenbergen, Monique Reijnierse, Tom W J Huizinga, Annette H M van der Helm van Mil
Objectives: The use of hand and foot MRI in the diagnostic process of RA has been advocated. Recent studies showed that MRI is helpful in predicting progression from clinically suspect arthralgia (CSA) to clinical arthritis, and from undifferentiated arthritis (UA) to RA. Symptom-free persons can also show inflammation on MRI. This study aimed to evaluate if MRI findings in symptom-free volunteers are relevant when defining a positive MRI. Methods: Two hundred and twenty-five CSA patients and two hundred and one UA patients underwent MRI of MCP, wrist and MTP joints at baseline and were followed for 1 year on progression to arthritis and RA, respectively, as reported previously...
October 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28955082/identification-of-tbc-using-mtp-64-protein-and-cord-formation
#11
Abdul Mannan, Shagufta Iram, Adeel Ahmad, Shahida Hussain, Bilal Munir Ahmad
Tuberculosis (TB) is an airborne infectious disease caused by Mycobacterium tuberculosis. The genus Mycobacterium comprises over 150 species. Non-tuberculosis Mycobacteria are the cause of opportunistic infections and frequently presents with similar clinical features like tuberculosis so species identification is important for management. The current study was designed for presumptive diagnosis of MTB by detecting MPT 64 and Cord formation and the sensitivity and specificity of Cord Formation in MGIT positive samples...
October 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28934874/radiographic-shape-of-foot-with-second-metatarsophalangeal-joint-dislocation-associated-with-hallux-valgus
#12
Tetsuro Kokubo, Takeshi Hashimoto, Yasunori Suda, Akeo Waseda, Hiroko Ikezawa
BACKGROUND: Second metatarsophalangeal (MTP) joint dislocation is associated with hallux valgus, and the treatment of complete dislocation can be difficult. The purpose of this study was to radiographically clarify the characteristic foot shape in the presence of second MTP joint dislocation. METHODS: Weight-bearing foot radiographs of the 268 patients (358 feet) with hallux valgus were examined. They were divided into 2 groups: those with second MTP joint dislocation (study group = 179 feet) and those without dislocation (control group = 179 feet)...
September 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28928235/testosterone-protects-high-fat-low-carbohydrate-diet-induced-non-alcoholic-fatty-liver-disease-in-castrated-male-rats-mainly-via-modulating-er-stress
#13
Yue Jia, Jennifer Kuang Yee, Christina Wang, Liana Nikolaenko, Maruja Diaz-Arjonilla, Joshua N Cohen, Samuel W French, Peter Y Liu, YanHe Lue, Wai-Nang Paul Lee, Ronald S Swerdloff
We previously showed that testosterone (T) deficiency enhanced high-fat diet (HFD) induced hepatic steatosis in rats that was independent of insulin resistance, and that T replacement reduced hepatic macrovesicular fat accumulation and inflammation. The present report explores the mechanism of T-protective effects on HFD-induced steatohepatitis. Adult male rats were randomized into four treatment groups for 15 weeks (intact rats on regular chow diet or HFD, and castrated rats on HFD with/without T replacement)...
September 19, 2017: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28925731/detection-of-metabolic-pattern-following-decompressive-craniectomy-in-severe-traumatic-brain-injury-a-microdialysis-study
#14
Deepak Gupta, Raghav Singla, Anna T Mazzeo, Eric B Schnieder, Vivek Tandon, S S Kale, A K Mahapatra
OBJECTIVE: The aim of the study was to detect mitochondrial dysfunction and ischaemia in severe traumatic brain injury and their relationship with outcome. METHODS: Forty-one patients with severe traumatic brain injury (TBI) who underwent decompressive craniectomy were prospectively monitored with intracerebral microdialysis catheters (MD). Variables related to energy metabolism were studied using microdialysis. RESULTS: Twentysix patients (63...
September 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28913378/first-metatarsophalangeal-joint-arthrodesis-a-retrospective-comparison-of-crossed-screws-locking-and-non-locking-plate-fixation-with-lag-screw
#15
Leif Claassen, Christian Plaass, Marc-Frederic Pastor, Sarah Ettinger, Mathias Wellmann, Christina Stukenborg-Colsman, Hazibullah Waizy, Sayyed Hadi Sayyed Hosseinian
BACKGROUND: Locking plate fixation is increasingly used for first metatarsophalangeal joint (MTP-I) arthrodesis. There are still few comparable clinical data regarding this procedure. In this study we aimed to compare the clinical and radiographical outcomes of crossed-screws, locking and non-locking plate fixation with lag screw for first metatarsophalangeal joint arthrodesis. METHODS: A total of 60 patients who had undergone arthrodesis of the MTP-I between January 2008 and June 2010 were retrospectively evaluated...
July 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/28894133/5-methoxytryptophan-protects-mscs-from-stress-induced-premature-senescence-by-upregulating-foxo3a-and-mtor
#16
Tzu-Ching Chang, Min-Fen Hsu, Chiu-Yueh Shih, Kenneth K Wu
5-methoxytryptophan (5-MTP) is a newly discovered tryptophan metabolite which controls stress-induced inflammatory signals. To determine whether 5-MTP protects against stress-induced mesenchymal stem cell (MSC) senescence, we incubated bone marrow-derived MSC (BM-MSC) in high-glucose medium or regular medium for 2 weeks followed by addiction of 5-MTP (10 μM) or vehicle for 48 h. 5-MTP reduced p16 and p21 expression, senescence-associated β-Gal (SA-β-Gal) and IL-6 secretion and increased BrdU incorporation...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28893990/cd1d-restricted-pathways-in-hepatocytes-control-local-natural-killer-t-cell-homeostasis-and-hepatic-inflammation
#17
Sebastian Zeissig, Kenneth Peuker, Shankar Iyer, Thomas Gensollen, Stephanie K Dougan, Torsten Olszak, Arthur Kaser, Richard S Blumberg
Invariant natural killer T (iNKT) cells recognize lipid antigens presented by CD1d and play a central role in regulating immunity and inflammation in peripheral tissues. However, the mechanisms which govern iNKT cell homeostasis after thymic emigration are incompletely understood. Here we demonstrate that microsomal triglyceride transfer protein (MTP), a protein involved in the transfer of lipids onto CD1d, regulates liver iNKT cell homeostasis in a manner dependent on hepatocyte CD1d. Mice with hepatocyte-specific loss of MTP exhibit defects in the function of CD1d and show increased hepatic iNKT cell numbers as a consequence of altered iNKT cell apoptosis...
September 26, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28885842/catalytic-activity-control-via-crossover-between-two-different-microstructures
#18
Yuheng Zhou, Yihan Zhu, Zhi-Qiang Wang, Shihui Zou, Guicen Ma, Ming Xia, Xueqian Kong, Liping Xiao, Xue-Qing Gong, Jie Fan
Metal nanocatalysts hold great promise for a wide range of heterogeneous catalytic reactions, while the optimization strategy of catalytic activity is largely restricted by particle size or shape control. Here, we demonstrate that a reversible microstructural control through the crossover between multiply twinned nanoparticle (MTP) and single crystal (SC) can be readily achieved by solvent post-treatment on gold nanoparticles (AuNPs). Polar solvents (e.g., water, methanol) direct the transformation from MTP to SC accompanied by the disappearance of twinning and stacking faults...
September 21, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28866046/formaldehyde-alters-triglyceride-synthesis-and-very-low-density-lipoprotein-secretion-in-a-time-dependent-manner
#19
Jianying Bai, Pan Wang, Yanfei Liu, Yan Zhang, Yaofu Li, Zhen He, Lifang Hou, Ruifeng Liang
Formaldehyde is a common indoor air pollutant that is toxic to the liver. This study aimed to investigate the effects of formaldehyde on triglyceride metabolism in human hepatocellular carcinoma cells (HepG2). Cell viability was detected using a MTT (3-(4,5-dimethylthiazol-2-Yl)-2,5-diphenyltetrazolium bromide) assay. Following treatment with different concentrations of formaldehyde for 24 and 48h, the intra and extra-hepatocellular triglyceride (TG) content was determined using a chemical-enzymatic method; Western blotting was used to detect the levels of fatty acid synthesis and VLDL-related proteins...
August 30, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28865581/the-rotoglide%C3%A2-total-replacement-of-the-first-metatarso-phalangeal-joint-a-prospective-series-with-7-15-years-clinico-radiological-follow-up-with-survival-analysis
#20
Hakon Kofoed, Lasse Danborg, Jacob Grindsted, Søren Merser
BACKGROUND: The Rotoglide total replacement of the MTP-1 joint. 15 years survival analysis. The purpose of this prospective study was to evaluate the long-term performance clinico-radiographically of an uncemented three-component total replacement for the first metatarso-phalangeal joint (MTP-1) used for hallux rigidus (primary osteoarthritis grades 3 and 4). The follow-up was median 11.5 years (7-15). METHODS: The AOFAS forefoot score was used preoperatively and at follow-up...
September 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
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