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https://www.readbyqxmd.com/read/29045961/-effects-of-recent-upper-respiratory-tract-infections-on-incidence-of-the-perioperative-respiratory-adverse-events-in-children-a-prospective-cohort-study
#1
C Q Li, D X Wang, T Cheng, X Y Zheng
OBJECTIVE: To investigate the effects of the recent upper respiratory tract infections (URI) on the incidence of perioperative respiratory adverse events in children scheduled to undergo general anesthesia and elective surgery. METHODS: In the study, 232 children undergoing general anesthesia with laryngeal mask airway (LMA) for elective ophthalmic surgeries at Peking University First Hospital, Beijing, China, from Nov. 1, 2015 to May 10, 2016 were enrolled. On the day of the surgery, the parents of the children were preoperatively asked to fill out a questionnaire regarding the baseline characteristics and medical history of the children, including gender, age, height, weight, history of URI within the last 2 weeks before anesthesia, history of premature, long-term passive smoking exposure, habitual sleep snoring, and history of asthma...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045949/effectiveness-of-a-home-based-active-video-game-programme-in-young-cystic-fibrosis-patients
#2
Tamara Del Corral, Maria Àngels Cebrià I Iranzo, Ibai López-de-Uralde-Villanueva, Roberto Martínez-Alejos, Isabel Blanco, Jordi Vilaró
BACKGROUND: Exercise-based rehabilitation is already a part of cystic fibrosis (CF) treatment; however, patient adherence is low. OBJECTIVES: To assess the effectiveness of a home exercise programme using active video games (AVGs) as a training modality for children and adolescents with CF. METHODS: Thirty-nine children with CF were randomised to a control group (CG, n = 20, age 11 ± 6 years; FEV1 86.2 ± 20.5% of predicted) or a training group (AVGG, n = 19, age 13 ± 3 years; FEV1 82...
October 19, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29045927/alkaline-ph-shock-enhanced-production-of-validamycin-a-in-fermentation-of-streptomyces-hygroscopicus
#3
Jing Jiang, Ya-Fang Sun, Xi Tang, Chao-Nan He, Ye-Lin Shao, Ya-Jie Tang, Wen-Wen Zhou
Validamycin A (Val-A) is produced by Streptomyces as a secondary metabolite with wide agricultural applications of controlling rice sheath blight, false smut and damping-off diseases. The effect of alkaline pH shock on enhancing Val-A production and its mechanism were investigated. A higher yield of Val-A was achieved by NaOH shock once or several times together with faster protein synthesis and sugar consumption and alkaline pH shock can increase Val-A production by 27.43%. Transcription of genes related to amino acid metabolism, carbon metabolism and electron respiratory chain was significantly up-regulated, accompanied by the substantial increase of respiratory activity and glutamate concentration...
October 6, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29045834/a-latent-propriospinal-network-can-restore-diaphragm-function-after-high-cervical-spinal-cord-injury
#4
Jared M Cregg, Kevin A Chu, Lydia E Hager, Rachel S J Maggard, Daimen R Stoltz, Michaela Edmond, Warren J Alilain, Polyxeni Philippidou, Lynn T Landmesser, Jerry Silver
Spinal cord injury (SCI) above cervical level 4 disrupts descending axons from the medulla that innervate phrenic motor neurons, causing permanent paralysis of the diaphragm. Using an ex vivo preparation in neonatal mice, we have identified an excitatory spinal network that can direct phrenic motor bursting in the absence of medullary input. After complete cervical SCI, blockade of fast inhibitory synaptic transmission caused spontaneous, bilaterally coordinated phrenic bursting. Here, spinal cord glutamatergic neurons were both sufficient and necessary for the induction of phrenic bursts...
October 17, 2017: Cell Reports
https://www.readbyqxmd.com/read/29045745/long-term-oral-appliance-therapy-improves-daytime-function-and-mood-in-upper-airway-resistance-syndrome-patients
#5
Luciana B M Godoy, Luciana Palombini, Dalva Poyares, Cibele Dal-Fabbro, Thaís Moura Guimarães, Priscila Calixto Klichouvicz, Sergio Tufik, Sonia Maria Togeiro
Objectives: To evaluate the long term effects of an oral appliance on clinical symptoms, respiratory sleep parameters, sleep quality and sustained attention in patients with Upper Airway Resistance Syndrome (UARS) compared with placebo. Methods: This study was a randomized placebo-controlled clinical trial. Thirty UARS patients were randomized in two groups: placebo and mandibular advancement device (MAD) groups. UARS criteria were presence of sleepiness (Epworth Sleepiness Scale ≥ 10) and/or fatigue (Modified Fatigue Impact Scale ≥ 38) associated with an apnea/hypopnea index (AHI) ≤ 5 and a respiratory disturbance index (RDI) > 5 events/hour of sleep, and/or flow limitation in more than 30% of total sleep time...
October 17, 2017: Sleep
https://www.readbyqxmd.com/read/29045741/respiratory-syncytial-virus-genotypes-host-immune-profiles-and-disease-severity-in-young-children-hospitalized-with-bronchiolitis
#6
Rosa Rodriguez-Fernandez, Lorena I Tapia, Chin-Fen Yang, Juan Pablo Torres, Susana Chavez-Bueno, Carla Garcia, Lisa M Jaramillo, Melissa Moore-Clingenpeel, Hasan S Jafri, Mark E Peeples, Pedro A Piedra, Octavio Ramilo, Asuncion Mejias
Background: Data on how RSV genotypes influence disease severity and host immune responses is limited. We characterized the genetic variability of RSV during five seasons, and evaluated the role of RSV subtypes, genotypes and viral loads on disease severity and host transcriptional profiles. Methods: Prospective, observational study including a convenience sample of healthy infants hospitalized with RSV bronchiolitis. Nasopharyngeal samples for viral load quantitation, typing and genotyping, and blood samples for transcriptome analyses were obtained within 24h of hospitalization...
October 17, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29045699/impact-of-hiv-on-the-burden-and-severity-of-influenza-illness-in-malawian-adults-a-prospective-cohort-and-parallel-case-control-study
#7
Antonia Ho, Stephen J Aston, Hannah Jary, Tamara Mitchell, Maaike Alaerts, Mavis Menyere, Jane Mallewa, Mulinda Nyirenda, Dean Everett, Robert S Heyderman, Neil French
Background: The impact of HIV infection on influenza incidence and severity in adults in sub-Saharan Africa is unclear. Seasonal influenza vaccination is recommended for HIV-infected persons in developed settings, but is rarely implemented in Africa. Methods: We conducted a prospective cohort study to compare the incidence of laboratory-confirmed influenza illness between HIV-infected and HIV-uninfected adults in Blantyre, Malawi. In a parallel case-control study, we explored risk factors for severe influenza presentation of severe (hospitalized lower respiratory tract infection (LRTI)), and mild influenza (influenza-like illness (ILI))...
October 16, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29045690/clinical-characteristics-of-hospitalized-infants-with-laboratory-confirmed-pertussis-in-guatemala
#8
Varun K Phadke, John P McCracken, Jennifer L Kriss, Maria R Lopez, Kim A Lindblade, Joe P Bryan, Miguel E Garcia, Carlos E Funes, Saad B Omer
Background: Pertussis is an important cause of hospitalization and death in infants too young to be vaccinated (aged <2 months). Limited data on infant pertussis have been reported from Central America. The aim of this study was to characterize acute respiratory illnesses (ARIs) attributable to Bordetella pertussis among infants enrolled in an ongoing surveillance study in Guatemala. Methods: As part of a population-based surveillance study in Guatemala, infants aged <2 months who presented with ARI and required hospitalization were enrolled, and nasopharyngeal and oropharyngeal swab specimens were obtained...
October 13, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29045689/sensitivity-to-house-dust-mites-allergens-with-atopic-asthma-and-its-relationship-with-cd14-c-159t-polymorphism-in-patients-of-west-bengal-india
#9
Amlan Ghosh, Shampa Dutta, Sanjoy Podder, Priti Mondal, Arghya Laha, Nimai Chandra Saha, Saibal Moitra, Goutam Kumar Saha, Richard Johnson
India is the home to around 15-20 million asthmatics, and asthma prevalence is increasing in Indian metropolitan area, including Kolkata, West Bengal. Complex interactions of genetic and environmental factors are involved in asthma. Genome-wide search for susceptible loci regulating IgE response (atopy) have identified a candidate gene CD14 which is most important in the context of allergic responses of respiratory system. This study was aimed to investigate the role of house dust and house dust mites in development of bronchial asthma and to explore the possible association of candidate gene CD14 with disease manifestation among Kolkata patient population...
October 17, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29045661/factors-associated-with-malnutrition-among-children-5-years-old-in-burkina-faso-evidence-from-the-demographic-and-health-surveys-iv-2010
#10
Ghislain G Poda, Chien-Yeh Hsu, Jane C-J Chao
Objective: To assess the factors associated with malnutrition among children <5 years in Burkina Faso. Design: This study was based on secondary analysis of cross-sectional population-based data from Burkina-Faso Demographic Health Surveys 2010. Setting: This study was carried out in Burkina Faso, West Africa. Participants: The participants were 6337 children <5 years and their mothers. Main outcome measures: Demographic characteristics, child nutrition and health status, and maternal and household information were collected...
October 17, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29045652/influence-of-pupation-substrate-on-mass-production-and-fitness-of-adult-anastrepha-obliqua-macquart-diptera-tephritidae-for-sterile-insect-technique-application
#11
Marysol Aceituno-Medina, José Pedro Rivera-Ciprian, Emilio Hernández, Anthony Clarke
Tephritid mass-rearing systems require an artificial substrate for pupation. Pupation substrate characteristics influence the quality of insects produced. Coconut fiber, as an alternative to the conventional pupation substrate vermiculite, was evaluated for Anastrepha obliqua Macquart (Diptera: Tephritidae) pupation behavior (pupation patterns, distribution, respiration rate, and pupal weight) and adult fitness (adult eclosion time, flight ability, and male mating competitiveness). Pupation percentage at 24 h, pupal weight, and flight ability were not significantly affected by substrate type...
October 16, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29045576/activation-of-cannabinoid-receptor-1-is-involved-in-protection-against-mitochondrial-dysfunction-and-cerebral-ischaemic-tolerance-induced-by-isoflurane-preconditioning
#12
M Cai, Q Yang, G Li, S Sun, Y Chen, L Tian, H Dong
Background: Isoflurane preconditioning (IPC) induces cerebral ischaemic tolerance, but the mechanism remains poorly understood. The aim of this study was to determine changes in mitochondrial function in the brain after IPC, and whether the cannabinoid receptor 1 (CB1R) could be involved in the mechanism of mitochondrial protection mediated by IPC. Methods: Adult male Sprague-Dawley rats were pretreated with isoflurane 2% for 1 h day-1, for 5 days consecutively, and then subjected to 120 min right middle cerebral artery occlusion...
October 13, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29045416/neonatal-immune-response-to-rhinovirus-a16-has-diminished-dendritic-cell-function-and-increased-b-cell-activation
#13
Amanda Barlow-Anacker, Yury Bochkov, James Gern, Christine M Seroogy
BACKGROUND: Rhinovirus infections during infancy account for the majority of respiratory illness health care utilization and are an associated risk factor for subsequent development of allergic asthma. Neonatal type I interferon production is diminished compared to adults after stimulation with TLR agonists. However, broad profiling of immune cell responses to infectious rhinovirus has not been undertaken and we hypothesized that additional immune differences can be identified in neonates...
2017: PloS One
https://www.readbyqxmd.com/read/29045356/addressing-safe-opioid-monitoring-practices-using-an-interprofessional-approach
#14
Marianne L Durham, AnnMarie Egan, Ann Jankiewicz, Marcia P Murphy, Patricia Nedved, Renee Luvich, Ann Goh, Louis Fogg
OBJECTIVE: The aims of the project are to increase knowledge related to opioids and improve adherence to evidence-based interventions for sedation monitoring and assessment in adult inpatients receiving opioids for pain through delivery of an interprofessional online program. BACKGROUND: Preventable opioid-induced respiratory depression is a patient safety risk in hospitals. Sedation and respiratory assessment and monitoring guidelines and tools are available to improve practice...
October 17, 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29045338/a-clinical-evaluation-of-the-impact-of-the-bayesian-penalized-likelihood-reconstruction-algorithm-on-pet-fdg-metrics
#15
Delphine Vallot, Olivier Caselles, Leonor Chaltiel, Anthony Fernandez, Erwan Gabiache, Lawrence Dierickx, Slimane Zerdoud, Mathilde Bauriaud, Frédéric Courbon
PURPOSE: The aim of this study was to evaluate the impact of using the Bayesian penalized likelihood (BPL) algorithm on a bismuth germanium oxide positron emission tomography (PET)/computed tomography (CT) system for F-FDG PET/CT exams in case of low injected activity and scan duration. MATERIALS AND METHODS: F-FDG respiratory gated PET/CT performed on 102 cancer patients, injected with ∼2 MBq/kg of F-FDG, were reconstructed using two algorithms: ordered subset expectation maximization (OSEM) and BPL...
November 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29045280/sedation-practice-in-extracorporeal-membrane-oxygenation-treated-patients-with-acute-respiratory-distress-syndrome-a-retrospective-study
#16
Julian deBacker, Erik Tamberg, Laveena Munshi, Lisa Burry, Eddy Fan, Sangeeta Mehta
Our objective was to characterize sedation management in adult patients with severe respiratory distress syndrome (ARDS) treated with venovenous extracorporeal membrane oxygenation (VV-ECMO). We conducted a retrospective chart review of these patients treated at Toronto General Hospital between January 2012 and October 2015. Medications administered (sedative, analgesic, paralytic, and antipsychotic), sedation depth (Sedation Agitation Scale [SAS] score) delirium assessments, and mobilization were recorded daily...
October 18, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29045255/listening-to-relaxing-music-improves-physiological-responses-in-premature-infants-a-randomized-controlled-trial
#17
Rafael A Caparros-Gonzalez, Alejandro de la Torre-Luque, Carolina Diaz-Piedra, Francisco J Vico, Gualberto Buela-Casal
BACKGROUND: Premature infants are exposed to high levels of noise in the neonatal intensive care unit (NICU). PURPOSE: This study evaluated the effect of a relaxing music therapy intervention composed by artificial intelligence on respiratory rate, systolic and diastolic blood pressure, and heart rate. METHODS: A double-blind, randomized, controlled trial was conducted in the NICUs of 2 general public hospitals in Andalusia, Spain. Participants were 17 healthy premature infants, randomly allocated to the intervention group or the control group (silence) at a 1:1 ratio...
October 17, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/29045243/use-of-ketamine-in-a-multimodal-analgesia-setting-for-rapid-opioid-tapering-in-a-profoundly-opioid-tolerant-patient-a-case-report
#18
Elise M Strickler, Eric S Schwenk, Mitchell J Cohen, Eugene R Viscusi
Opioids are frequently used for the treatment of chronic pain, and patients taking high doses are at increased risk of complications and adverse opioid-related events. Ketamine is appealing as an opioid adjunct because of its lack of respiratory depression and potential prevention of hyperalgesia and central sensitization. We present a case in which a ketamine infusion was utilized over a 7-day period to provide rapid taper of a daily dose of 400 mg of morphine equivalents to less than one-third of that dose on discharge with unchanged pain levels and no symptoms of opioid withdrawal...
October 17, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29045239/contour-propagation-for-lung-tumor-delineation-in-4d-ct-using-tensor-product-surface-of-uniform-and-non-uniform-closed-cubic-b-splines
#19
Renchao Jin, Yongchuan Liu, Mi Chen, Sheng Zhang, Enmin Song
A robust contour propagation method is proposed to help physicians delineate lung tumors on all phase images of four-dimensional computer tomography (4D-CT) by only manually delineating the contours on a reference phase. The proposed method models the trajectory surface swept by a contour in a respiratory cycle as a tensor-product surface of two closed cubic B-spline curves: a non-uniform B-spline curve which models the contour and a uniform B-spline curve which models the trajectory of a point on the contour...
October 18, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29044658/gills-of-the-medaka-oryzias-latipes-a-scanning-electron-microscopy-study
#20
Isabelle Leguen
The general morphology and surface ultrastructure of the gills of adult and larvae medaka (Oryzias latipes) were studied in freshwater and seawater using scanning electron microscopy. The gills of all examined fish were structurally similar to those of other teleosts and consisted of four pairs of arches supporting (i) filaments bearing lamellae and (ii) rakers containing taste buds. Three cell types, specifically pavement cells, mitochondria-rich cells (MRCs), and mucous cells, constituted the surface layer of the gill epithelium...
October 17, 2017: Journal of Morphology
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