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https://www.readbyqxmd.com/read/29773297/the-clinical-practice-of-high-flow-nasal-cannula-oxygen-therapy-in-adults-a-japanese-cross-sectional-multicenter-survey
#1
Jiro Ito, Kazuma Nagata, Susumu Sato, Akira Shiraki, Naoki Nishimura, Shinyu Izumi, Ryo Tachikawa, Takeshi Morimoto, Keisuke Tomii
BACKGROUND: High-flow nasal cannula oxygen therapy (HFNC) is widely used mainly in the acute care setting, but limited data are available on real-world practice in adults. The objective of this study was to describe HFNC practices in Japanese adults. METHODS: A retrospective cross-sectional multicenter survey of adult patients receiving HFNC from January through March 2015 was conducted in 33 participating hospitals in Japan. RESULTS: We obtained information on 321 patients (median age, 76; 218 men, 103 women; median estimated PaO2 /FI O2, 178 mm Hg) from 22 hospitals...
May 2018: Respiratory Investigation
https://www.readbyqxmd.com/read/29772177/capture-ferment-upgrade-a-three-step-approach-for-the-valorization-of-sewage-organics-as-commodities
#2
Abbas Alloul, Ramon Ganigue, Marc Spiller, Francis A Meerburg, Cristina Cagnetta, Korneel Rabaey, Siegfried E Vlaeminck
This critical review outlines a roadmap for the conversion of chemical oxygen demand (COD) contained in sewage to commodities based on three-steps: capture COD as sludge, ferment it to volatile fatty acids (VFA), and upgrade VFA to products. The article analyzes the state-of-the-art of this three-step approach and discusses the bottlenecks and challenges. The potential of this approach is illustrated for the European Union's 28 member states (EU-28) through Monte Carlo simulations. High-rate contact stabilization captures the highest amount of COD (66-86 gCOD person equivalent-1 day-1 in 60% of the iterations)...
May 17, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29769568/cu-cu-2-o-nanocomposite-films-as-a-p-type-modified-layer-for-efficient-perovskite-solar-cells
#3
You-Jyun Chen, Ming-Hsien Li, Jung-Chun-Andrew Huang, Peter Chen
Cu/Cu2 O films grown by ion beam sputtering were used as p-type modified layers to improve the efficiency and stability of perovskite solar cells (PSCs) with an n-i-p heterojunction structure. The ratio of Cu to Cu2 O in the films can be tuned by the oxygen flow ratio (O2 /(O2  + Ar)) during the sputtering of copper. Auger electron spectroscopy was performed to determine the elemental composition and chemical state of Cu in the films. Ultraviolet photoelectron spectroscopy and photoluminescence spectroscopy revealed that the valence band maximum of the p-type Cu/Cu2 O matches well with the perovskite...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29769538/organic-matter-loading-by-hippopotami-causes-subsidy-overload-resulting-in-downstream-hypoxia-and-fish-kills
#4
Christopher L Dutton, Amanda L Subalusky, Stephen K Hamilton, Emma J Rosi, David M Post
Organic matter and nutrient loading into aquatic ecosystems affects ecosystem structure and function and can result in eutrophication and hypoxia. Hypoxia is often attributed to anthropogenic pollution and is not common in unpolluted rivers. Here we show that organic matter loading from hippopotami causes the repeated occurrence of hypoxia in the Mara River, East Africa. We documented 49 high flow events over 3 years that caused dissolved oxygen decreases, including 13 events resulting in hypoxia, and 9 fish kills over 5 years...
May 16, 2018: Nature Communications
https://www.readbyqxmd.com/read/29768261/n-cadherin-attenuates-high-glucose-induced-nucleus-pulposus-cell-senescence-through-regulation-of-the-ros-nf-%C3%AE%C2%BAb-pathway
#5
Gang Hou, Huiqing Zhao, Haijun Teng, Pei Li, Wenbin Xu, Junbin Zhang, Lulu Lv, Zhiliang Guo, Li Wei, Hui Yao, Yichun Xu
BACKGROUND/AIMS: Diabetes mellitus (DM) is a potential etiology of disc degeneration. N-cadherin (N-CDH) helps maintain the cell viability, cell phenotype and matrix biosynthesis of nucleus pulposus (NP) cells. Here, we mainly aimed to investigate whether N-CDH can attenuate high glucose-induced NP cell senescence and its potential mechanism. METHODS: Rat NP cells were cultured in a base culture medium and base culture medium with a 0.2 M glucose concentration. Recombinant lentiviral vectors were used to enhance N-CDH expression in NP cells...
May 11, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29767974/in-vitro-and-in-vivo-demonstration-of-human-ovarian-cancer-necrosis-through-a-water-soluble-and-near-infrared-absorbing-chlorin
#6
Betsy Marydasan, Bollapalli Madhuri, Shirisha Cherukommu, Jedy Jose, Mambattakkara Viji, Suneesh C Karunakaran, Tavarekere K Chandrashekar, Kunchala Sridhar Rao, Ch Mohan Rao, Danaboyina Ramaiah
With an objective to develop efficient sensitizers for therapeutical applications, we synthesized a water soluble, 5,10,15,20-tetrakis(3,4-dihydroxyphenyl)chlorin (TDC), and investigated its in vitro and in vivo biological efficacy and compared with the commercially available sensitizers. TDC showed high water solubility (6-fold), when compared to Foscan and exhibited excellent triplet excited state () and singlet oxygen () yields. In vitro photobiological investigations in human ovarian cancer cell lines SKOV-3 showed high photocytotoxicity, negligible dark toxicity, rapid cellular uptake and specific localization of TDC in neoplastic cells as assessed by flow cytometric cell-cycle and propidium iodide staining analysis...
May 16, 2018: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29765682/effects-of-the-inclusion-of-a-mixed-psychrotrophic-bacteria-strain-for-sewage-treatment-in-constructed-wetland-in-winter-seasons
#7
Meizhen Tang, Zhengtao Li, Yuewei Yang, Junfeng Chen, Jie Jiang
Constructed wetlands (CWs) have been used globally in wastewater treatment for years. CWs represent an efficient ecological system which is both energy-saving and low in investment for construction and operational cost. In addition, CWs also have the advantage of being easy to operate and maintain. However, the operation of CWs at northern latitudes (both mid and high) is sometimes quite demanding, due to the inhibitory effect of low temperatures that often occur in winter. To evaluate the wastewater treatment performance of a culture of mixed Psychrotrophic bacteria strains in an integrated vertical-flow CW, the removal rates of ammonia nitrogen (NH3 -N), chemical oxygen demand (COD), nitrite nitrogen [Formula: see text], nitrate nitrogen [Formula: see text] and total phosphorus (TP) were quantified at different bacterial dosages to determine the best bacterial dosage and establish kinetic degradation models of the mixed strains...
April 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29764401/management-of-acute-respiratory-failure-in-interstitial-lung-diseases-overview-and-clinical-insights
#8
REVIEW
Paola Faverio, Federica De Giacomi, Luca Sardella, Giuseppe Fiorentino, Mauro Carone, Francesco Salerno, Jousel Ora, Paola Rogliani, Giulia Pellegrino, Giuseppe Francesco Sferrazza Papa, Francesco Bini, Bruno Dino Bodini, Grazia Messinesi, Alberto Pesci, Antonio Esquinas
BACKGROUND: Interstitial lung diseases (ILDs) are a heterogeneous group of diseases characterized by widespread fibrotic and inflammatory abnormalities of the lung. Respiratory failure is a common complication in advanced stages or following acute worsening of the underlying disease. Aim of this review is to evaluate the current evidence in determining the best management of acute respiratory failure (ARF) in ILDs. METHODS: A literature search was performed in the Medline/PubMed and EMBASE databases to identify studies that investigated the management of ARF in ILDs (the last search was conducted on November 2017)...
May 15, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29761310/characteristics-of-patients-with-a-relatively-greater-minimum-ve-vco-2-against-peak-vo-2-and-impaired-exercise-tolerance
#9
Taisuke Nakade, Hitoshi Adachi, Makoto Murata, Shigeru Oshima
PURPOSE: Cardiopulmonary exercise testing (CPX) is used to evaluate functional capacity and assess prognosis in cardiac patients. Ventilatory efficiency (VE/VCO2 ) reflects ventilation-perfusion mismatch; the minimum VE/VCO2 value (minVE/VCO2 ) is representative of pulmonary arterial blood flow in individuals without pulmonary disease. Usually, minVE/VCO2 has a strong relationship with the peak oxygen uptake (VO2 ), but dissociation can occur. Therefore, we investigated the relationship between minVE/VCO2 and predicted peak VO2 (peak VO2 %) and evaluated the parameters associated with a discrepancy between these two parameters...
May 14, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29761012/an-overview-of-protective-strategies-against-ischemia-reperfusion-injury-the-role-of-hyperbaric-oxygen-preconditioning
#10
Ciprian Hentia, Alex Rizzato, Enrico Camporesi, Zhongjin Yang, Danina M Muntean, Dorel Săndesc, Gerardo Bosco
Introduction: Ischemia/reperfusion (I/R) injury, such as myocardial infarction, stroke, and peripheral vascular disease, has been recognized as the most frequent causes of devastating disorders and death currently. Protective effect of various preconditioning stimuli, including hyperbaric oxygen (HBO), has been proposed in the management of I/R. Methods: In this study, we searched and reviewed up-to-date published papers to explore the pathophysiology of I/R injury and to understand the mechanisms underlying the protective effect of HBO as conditioning strategy...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29758879/inhibition-of-element-sulfur-and-calcium-oxide-on-the-formation-of-pcdd-fs-during-co-combustion-experiment-of-municipal-solid-waste
#11
Hongting Ma, Na Du, Xueyin Lin, Chaofan Liu, Jingyu Zhang, Zhuangzhuang Miao
In order to investigate the effect of element sulfur (S) and calcium oxide (CaO) on the formation of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) during municipal solid waste (MSW) combustion process, MSW was incinerated with S or CaO in a laboratory-scale incinerator and heated in the flow of N2 -O2 gas mixture at 800°C. It can be concluded that 25% of oxygen concentration is the best condition for the following inhibitors experiments through a series of oxygen variation experiments...
August 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29756209/high-flow-oxygen-insufflation-into-the-trachea-during-endolaryngeal-surgery
#12
Ozlem O Celebi, Patcharamanee Wangchalabovorn, Christine Mai, Ramon A Franco
No abstract text is available yet for this article.
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29756164/methods-for-the-determination-of-skeletal-muscle-blood-flow-development-strengths-and-limitations
#13
REVIEW
Lasse Gliemann, Stefan P Mortensen, Ylva Hellsten
Since the first measurements of limb blood flow at rest and during nerve stimulation were conducted in the late 1800s, a number of methods have been developed for the determination of limb and skeletal muscle blood flow in humans. The methods, which have been applied in the study of aspects such as blood flow regulation, oxygen uptake and metabolism, differ in terms of strengths and degree of limitations but most have advantages for specific settings. The purpose of this review is to describe the origin and the basic principles of the methods, important aspects and requirements of the procedures...
May 14, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29755755/lung-volumes-identify-an-at-risk-group-in-persons-with-prolonged-secondhand-tobacco-smoke-exposure-but-without-overt-airflow-obstruction
#14
Mehrdad Arjomandi, Siyang Zeng, Jeroen Geerts, Rachel K Stiner, Bruce Bos, Ian van Koeverden, Jason Keene, Brett Elicker, Paul D Blanc, Warren M Gold
Introduction: Exposure to secondhand smoke (SHS) is associated with occult obstructive lung disease as evident by abnormal airflow indices representing small airway disease despite having preserved spirometry (normal forced expiratory volume in 1 s-to-forced vital capacity ratio, FEV1 /FVC). The significance of lung volumes that reflect air trapping in the presence of preserved spirometry is unclear. Methods: To investigate whether lung volumes representing air trapping could determine susceptibility to respiratory morbidity in people with SHS exposure but without spirometric chronic obstructive pulmonary disease, we examined a cohort of 256 subjects with prolonged occupational SHS exposure and preserved spirometry...
2018: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/29754079/urban-stormwater-treatment-by-a-constructed-wetland-seasonality-impacts-on-hydraulic-efficiency-physico-chemical-behavior-and-heavy-metal-occurrence
#15
M Walaszek, P Bois, J Laurent, E Lenormand, A Wanko
Urban stormwater affects the general quality of water bodies because of their hydraulic and pollution impacts. Stormwater discharges modify stream water flow and are reported as major source of heavy metals (HMs) in urban streams. Stormwater Constructed Wetlands (SCWs) have been built worldwide to manage stormwater before it is released into hydrosystems. In SCWs, stormwater is stored, evaporated and sometimes infiltrated. Subsequently, the HMs in stormwater can be settled, filtered and bioassimilated by microorganisms...
May 9, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29751198/price-to-pay-portal-vein-arterialization-for-hepatic-artery-thrombosis-after-living-donor-liver-transplantation-a-case-report
#16
Worakitti Lapisatepun, Anon Chotirosniramit, Trichak Sandhu, Kanya Udomsin, Wasana Ko-Iam, Phuriphong Chanthima, Warangkana Lapisatepun, Settapong Boonsri, Suraphong Lorsomradee, Quanhathai Kaewpoowat, Sunhawit Junrungsee
OBJECTIVE: Hepatic artery thrombosis (HAT) is one of the most serious complications of liver transplantation that can potentially lead to loss of the allograft. Retransplantation is the only option when revascularization can't be performed but the donor may be not available in the short period of time. We report the technique of using portal vein arterialization (PVA) for bridging before retransplantation. There are few reports in living donor setting. CASE DESCRIPTION: The recipient of the liver was a 59 year old male who received an extended right lobe graft from his son...
May 2, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29750833/high-flow-oxygen-therapy-is-safe-and-effective-in-infants-with-bronchiolitis
#17
EDITORIAL
Matti Korppi, Terhi Tapiainen
No abstract text is available yet for this article.
May 11, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29750694/impact-of-2-distinct-levels-of-mean-arterial-pressure-on-near-infrared-spectroscopy-during-cardiac-surgery-secondary-outcome-from-a-randomized-clinical-trial
#18
Frederik Holmgaard, Anne G Vedel, Theis Lange, Jens C Nilsson, Hanne B Ravn
BACKGROUND: Near-infrared spectroscopy (NIRS) is used worldwide to monitor regional cerebral oxygenation (rScO2) during cardiopulmonary bypass (CPB). Intervention protocols meant to mitigate cerebral desaturation advocate to increase mean arterial pressure (MAP) when cerebral desaturation occurs. However, the isolated effect of MAP on rScO2 is uncertain. The aim of the present study was in a randomized, blinded design to elucidate the effect of 2 distinct levels of MAP on rScO2 values during CPB...
May 9, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29750296/hyperoside-protects-human-kidney%C3%A2-2-cells-against-oxidative-damage-induced-by-oxalic-acid
#19
Yongliang Chen, Lihong Ye, Wangjian Li, Dongzhang Li, Feng Li
The majority of renal calculi (kidney stones) are calcium stones. Oxidative damage to renal tubular epithelial cells induced by reactive oxygen species (ROS) is the predominant cause of calcium oxalate stone formation. Hyperoside (Hyp) is a flavonol glycoside extracted from medicinal plants and appears to exhibit potent antioxidant activity in various cells. The aim of the present study was to investigate the protective effect of Hyp on renal cells exposed to oxidative stress simulated by oxalic acid (OA), and to determine whether the underlying mechanism involves the nuclear factor E2‑related factor2 (Nrf2)‑antioxidative response element signaling pathway...
May 2, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29750294/lncrna-uc-48-is-involved-in-the-diabetic-immune-and-inflammatory-responses-mediated-by-p2x7-receptor-in-raw264-7-macrophages
#20
Hong Wu, Fang Wen, Mei Jiang, Qiang Liu, Yijun Nie
High glucose combined with high FFAs can contribute to the unfavorable development of type 2 diabetes mellitus (T2DM) and monocytes/macrophages are important in the occurrence and development of T2DM, which is regarded as a type of low‑grade inflammation. Although our previous study demonstrated that increased expression of P2X7 receptor (P2X7R) in peripheral blood monocytes may alter the innate immune system and that long non‑coding (lnc)RNA uc.48+ was involved in diabetic neuropathic pain, the involvement of uc...
May 9, 2018: International Journal of Molecular Medicine
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