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https://www.readbyqxmd.com/read/30531421/fluorescein-angiography-findings-in-unilateral-persistent-fetal-vasculature
#1
Jen-Hsiang Shen, Laura Liu, Nan-Kai Wang, Yih-Shiou Hwang, Kuan-Jen Chen, An-Ning Chao, Chi-Chun Lai, Tun-Lu Chen, Wei-Chi Wu
OBJECTIVE: This study aims to examine retinal vascular findings for affected eyes and contralateral eyes as well in typical cases of unilateral persistent fetal vasculature. METHODS: We retrospectively reviewed all patients evaluated at Chang Gung Memorial Hospital, Linkou, for unilateral persistent fetal vasculature between January 2008 and July 2017. All patients underwent fluorescein angiography (FA) examination under general anesthesia. FA was performed using RetCam 3 (Clarity Medical Systems, Inc, Pleasanton, CA)...
November 28, 2018: Retina
https://www.readbyqxmd.com/read/30531188/glaucoma-work-up-in-congenital-zika-syndrome
#2
Daniela R de Oliveira, Camila V Ventura, Bruno L B Esporcatte, Carolina P B Gracitelli, Natalia de Carvalho Dias, Liana O Ventura, Rubens Belfort, Christiane Rolim-de-Moura
PURPOSE: To perform a glaucoma work-up in infants with congenital Zika syndrome (CZS). PATIENT AND METHODS: This cross-sectional study included 188 eyes of 107 children (1.1 ± 0.3▒y [range, 0.3-1.8▒y]) with CZS. The confirmation of the syndrome was possible in 77/107 (72.0%) of the enrolled infants based on positive immunoglobulin M antibody capture enzyme-linked immunosorbent assay for Zika virus in the cerebrospinal fluid. All infants underwent a complete ophthalmic examination and bilateral fundus imaging was captured using a wide-angle digital fundus camera (RetCam™; Natus Medical Inc...
December 10, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/30508927/central-corneal-thickness-changes-and-horizontal-corneal-diameter-in-premature-infants-a-prospective-analysis
#3
May May Choo, Choo Mee Yeong, John R Grigg, Nurliza Khaliddin, Azida Juana Kadir, Elizabeth H Barnes, Tengku Ain Kamalden, Stephanie L Watson
To report observations of horizontal corneal diameter (HCD) and central corneal thickness (CCT) changes in premature infants with stable optic disc cupping and intraocular pressures (IOPs). The HCD and CCT at term serve as a baseline for premature infants.Sixty-three premature infants were enrolled in a prospective case series. HCD, CCT, and IOP were measured. RetCam images of the optic discs were used to evaluate the cup-disc ratio (CDR) and read by an independent masked observer. Data were collected at between preterm (32-36 weeks) and again at term (37-41 weeks) postconceptual age...
November 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30442486/screening-for-retinopathy-of-prematurity-by-telemedicine-in-a-tertiary-level-neonatal-intensive-care-unit-in-france-review-of-a-six-year-period
#4
H Chan, A Cougnard-Grégoire, J F Korobelnik, M N Delyfer, D Touboul, V Coste, J Sarlangue, C Dutheil, C Paya
PURPOSE: To analyze the prevalence and risk factors for retinopathy of prematurity (ROP) and severe (treatment-requiring) ROP. METHODS: A retrospective study was conducted in a level III neonatal unit in Bordeaux, France, from 2009 to 2015. Four hundred and nineteen preterm infants who were screened for ROP exclusively by RetCam were included. RESULTS: ROP of any degree was diagnosed in 27.68% of infants. Stages 1, 2, 3 and 4 ROP was found in 44%, 46%, 9% and 1% of subjects, respectively...
November 12, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/30126460/the-efficacy-and-safety-of-retcam-in-detecting-neonatal-retinal-hemorrhages
#5
Feng Chen, Dan Cheng, Jiandong Pan, Chongbin Huang, Xingxing Cai, Zhongxu Tian, Fan Lu, Lijun Shen
BACKGROUND: To investigate the ability of characterizing neonatal retinal hemorrhage (RH) using RetCam in healthy newborns and the systemic effects during the procedure. METHODS: This prospective study enrolled 68 healthy newborns aged 2 to 4 days old. The RH was imaged and classified according to the location and numbers of hemorrhages. The heart rate (HR), respiration rate (RR), and oxygen saturation (OS) were recorded at 4 time points before (Phase 1, P1), during (P2 and P3) and after the examination (P4)...
August 20, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/30120130/fundus-examination-of-199-851-newborns-by-digital-imaging-in-china-a-multicentre-cross-sectional-study
#6
He Tang, Na Li, Zhan Li, Meiju Zhang, Meirong Wei, Changbing Huang, Jihong Wang, Fuxin Li, Hong Wang, Zijiang Liu, Liying He, Yangyang Cheng, Wei Chen, Liwen Jin, Limin Gong, Jun Lu, Yan Xue, Manxiang Su, Yanhong Wang, Haiming Mo, Zhenwen Chen, Wei Guo, Yun Li, Hong Pan, Wei Zhang, Xu Ma, Xi Jin, Binbin Wang
BACKGROUND: The prevalence of ocular abnormalities of newborn in China has seldom been reported. To report the implementation of digital imaging in ocular screening of all newborns in multiple centres in China and to describe the abnormal findings of fundus examination, we did the cross-sectional study. METHODS: Fundus examinations were performed on newborns within the 42 days after birth using a RetCam wide-field digital imaging system. Digital images of the posterior pole, superior, nasal and temporal retinal fields of each participant were taken...
August 17, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/30080144/automated-analysis-for-retinopathy-of-prematurity-by-deep-neural-networks
#7
Junjie Hu, Yuanyuan Chen, Jie Zhong, Rong Ju, Zhang Yi
Retinopathy of Prematurity (ROP) is a retinal vasproliferative disorder disease principally observed in infants born prematurely with low birth weight. ROP is an important cause of childhood blindness. Although automatic or semiautomatic diagnosis of ROP has been conducted, most previous studies have focused on "plus" disease, which is indicated by abnormalities of retinal vasculature. Few studies have reported methods for identifying the "stage" of ROP disease. Deep neural networks have achieved impressive results in many computer vision and medical image analysis problems, raising expectations that it might be a promising tool in automatic diagnosis of ROP...
August 6, 2018: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/30063746/diagnostic-accuracy-of-a-digital-fundus-photographic-system-for-detection-of-retinopathy-of-prematurity-requiring-treatment-rop-rt
#8
Phanthipha Wongwai, Sirinya Suwannaraj, Somkiat Asawaphureekorn
OBJECTIVES: To evaluate the diagnostic accuracy of a digital fundus photographic system that consists of taking fundus photographs by a trained technician using a RetCam® shuttle and interpreting fundus images by an expert to detect Retinotapthy of Prematurity requiring treatment (ROP-RT) which defined as type I ROP according to the Early Treatment for ROP study (ETROP). MATERIALS AND METHODS: One hundred infants were examined by (1) an expert ophthalmologist experienced in ROP care using indirect ophthalmoscopy; (2) digital wide-field imaging by a trained technician using a RetCam® shuttle and images were sent remotely for interpretation by two ophthalmologists experienced in ROP care (Reader A, and Reader B); and (3) local ophthalmologists using indirect ophthalmoscopy...
2018: PloS One
https://www.readbyqxmd.com/read/30021036/findings-in-persistent-retinopathy-of-prematurity
#9
Clinton C Warren, Jonathon B Young, Mara R Goldberg, Thomas B Connor, Iris S Kassem, Deborah M Costakos
BACKGROUND AND OBJECTIVE: To determine whether retinopathy of prematurity (ROP) that persists beyond a postmenstrual age (PMA) of 45 weeks has abnormalities that can be documented by fundus photography or fluorescein angiography (FA). PATIENTS AND METHODS: Fundus photographs and FAs were reviewed for all premature infants who underwent FA for persistent ROP after 45 weeks PMA. RESULTS: Of the 487 infants who were screened for ROP, 16 (3.3%) demonstrated ROP beyond 45 weeks...
July 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29548839/comparison-of-the-characteristics-of-retinal-hemorrhages-in-abusive-head-trauma-versus-normal-vaginal-delivery
#10
So Young Kim, Linda A Morgan, Andrew J Baldwin, Donny W Suh
BACKGROUND: Retinal hemorrhage (RH) is one of the hallmarks of abusive head trauma (AHT); however, RH is also encountered with normal vaginal deliveries (NVD) and thus presents the clinician with a diagnostic dilemma. The purpose of this study was to compare RHs in AHT with those of NVD. METHODS: Records of with AHT and NVD infants with RH evaluated from 2013 to 2015 were reviewed retrospectively. Pattern, size, extent, and severity were compared using RetCam images...
April 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29540871/clinical-pattern-of-retinoblastoma-in-pakistani-population-review-of-403-eyes-in-295-patients
#11
Mohammad Idrees Adhi, Sumbul Kashif, Kashif Muhammed, Nisar Siyal
OBJECTIVE: To document clinical pattern of retinoblastoma in Pakistani population. METHODS: This retrospective study, which was conducted at Department of Ophthalmology, Dow University of Health Sciences, Karachi, reviewed clinical records of patients with retinoblastoma from 1997 to 2012. Staging of disease was done by referring to retinal diagrams, RetCam images, and first magnetic resonance imaging. Ophthalmic notes, imaging reports and histopathology reports of enucleated eyes established optic nerve involvement...
March 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/29253301/full-term-neonatal-ophthalmic-screening-in-china-a-review-of-4-year-outcomes
#12
Li-Hong Li, Wei-Chi Wu, Na Li, Jun Lu, Guo-Ming Zhang, Jun-Yang Zhao, Yan Ma
BACKGROUND AND OBJECTIVE: To report the 4-year outcomes of a neonatal ophthalmic screening program in the Kunming Maternity and Child Care Hospital of Kunming City, Kunming, China. PATIENTS AND METHODS: This was a retrospective, observational case series study. Newborns who underwent neonatal eye screening using the RetCam system (Clarity Medical Systems, Pleasanton, CA) at the authors' hospital from March 2010 to February 2014 were included. RESULTS: Of the 15,284 full-term infants who participated in the program, 21% (3,171 of 15,284) had some ocular abnormalities...
December 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29095074/evaluation-of-retinopathy-of-prematurity-incidence-with-telemedicine-confirmation-in-gansu-china-a-pilot-study
#13
Xinxin Zhang, Yuping Wang, J Niklas Ulrich, Yi Yang, Leona Ding, Yi Yang, Ding Xu, Kristina Tarczy-Hornoch, Michelle T Cabrera
PURPOSE: To determine the incidence of retinopathy of prematurity (ROP) in Gansu, China by combining bedside examinations with remote RetCam (Clarity Medical Systems, Pleasanton, CA, USA) diagnosis. METHODS: ROP screening via indirect ophthalmoscopy followed by RetCam imaging was performed from 2014 to 2015. Three ROP-experienced ophthalmologists interpreted images remotely. Incidence of ROP was determined by combining bedside and telemedicine diagnoses. RESULTS: Of 139 examined infants and 137 complete records, 20 (14...
November 2, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/29022295/retinopathy-of-prematurity-assist-novel-software-for-detecting-plus-disease
#14
Elias Khalili Pour, Hamidreza Pourreza, Kambiz Ameli Zamani, Alireza Mahmoudi, Arash Mir Mohammad Sadeghi, Mahla Shadravan, Reza Karkhaneh, Ramak Rouhi Pour, Mohammad Riazi Esfahani
PURPOSE: To design software with a novel algorithm, which analyzes the tortuosity and vascular dilatation in fundal images of retinopathy of prematurity (ROP) patients with an acceptable accuracy for detecting plus disease. METHODS: Eighty-seven well-focused fundal images taken with RetCam were classified to three groups of plus, non-plus, and pre-plus by agreement between three ROP experts. Automated algorithms in this study were designed based on two methods: the curvature measure and distance transform for assessment of tortuosity and vascular dilatation, respectively as two major parameters of plus disease detection...
December 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28905829/variation-in-the-vitreoretinal-configuration-of-stage-4-retinopathy-of-prematurity-in-photocoagulated-and-treatment-naive-eyes-undergoing-vitrectomy
#15
Salil Sharad Gadkari, Madan Deshpande
PURPOSE: We sought to document the difference in the vitreoretinal configuration of Stage 4 retinopathy of prematurity (ROP) in photocoagulated and treatment naive eyes undergoing vitrectomy and to correlate it with surgical complexity. METHODS: Consecutive eyes posted for vitrectomy with Stage 4 ROP were documented preoperatively using a RetCam for the presence of peripheral traction (PT), presence of central traction just outside the arcades, and presence of traction extending to the lens...
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28780616/the-analysis-of-posterior-segment-findings-in-term-and-premature-infants-using-retcam-images
#16
Huseyin Gursoy, Mustafa Deger Bilgec, Nazmiye Erol, Hikmet Basmak, Ertugrul Colak
OBJECTIVE: To analyze posterior segment findings in term and premature infants using the RetCam image database. METHODS: RetCam images taken of infants born between January 2012 and December 2015 were reviewed. Group 1 included infants with posterior segment findings other than retinopathy of prematurity (ROP). Group 2 included infants with mild-to-severe ROP. The baseline characteristics, anterior segment findings, and percentage of infants who received treatment were compared among the 2 groups...
October 2018: International Ophthalmology
https://www.readbyqxmd.com/read/28752837/an-international-comparison-of-retinopathy-of-prematurity-grading-performance-within-the-benefits-of-oxygen-saturation-targeting-ii-trials
#17
RANDOMIZED CONTROLLED TRIAL
B W Fleck, C Williams, E Juszczak, K Cocker, B J Stenson, B A Darlow, S Dai, G A Gole, G E Quinn, D K Wallace, A Ells, S Carden, L Butler, D Clark, J Elder, C Wilson, S Biswas, A Shafiq, A King, P Brocklehurst, A R Fielder
PurposeTo investigate whether the observed international differences in retinopathy of prematurity (ROP) treatment rates within the Benefits of Oxygen Saturation Targeting (BOOST) II trials might have been caused by international variation in ROP disease grading.MethodsGroups of BOOST II trial ophthalmologists in UK, Australia, and New Zealand (ANZ), and an international reference group (INT) used a web based system to grade a selection of RetCam images of ROP acquired during the BOOST II UK trial. Rates of decisions to treat, plus disease grading, ROP stage grading, ROP zone grading, inter-observer variation within groups and intra-observer variation within groups were measured...
January 2018: Eye
https://www.readbyqxmd.com/read/28737759/outcome-of-universal-newborn-eye-screening-with-wide-field-digital-retinal-image-acquisition-system-a-pilot-study
#18
P Goyal, T R Padhi, T Das, L Pradhan, S Sutar, S Butola, U C Behera, L Jain, S Jalali
PurposeTo evaluate the outcome of universal newborn eye screening with wide-field digital retinal imaging (WFDRI) system.MethodsIn this pilot study, we examined 1152 apparently healthy newborn infants in the obstetrics and gynecology ward of a civil hospital in Eastern India over 1.5 years. The examination included external eye examination, red reflex test and fundus imaging by WFDRI (RetCam II, Clarity medical system, Pleasanton, CA, USA) by a trained optometrist. The pathologies detected, net monetary gain and skilled manpower saved were documented...
January 2018: Eye
https://www.readbyqxmd.com/read/28671322/factors-related-to-retinal-haemorrhage-in-infants-born-at-high-risk
#19
Qinglan Pu, Ping Li, Huiqin Jiang, Hong Wang, Qiaoyun Zhou, Jia Liu, Wenhua Zhong, Huafei Huang
PURPOSE: This study aims to determine risk factors for retinal haemorrhage (RH) in high-risk infants. METHODS: A total of 3123 cases with high-risk pregnancy and/or neonatal asphyxia 72 hr after delivery were enrolled into this study. Fundus examinations were performed on newborns utilizing a wide-angle imaging system (RetCam III). Retinal haemorrhage (RH) was classified into three grades. Maternal, obstetric and neonatal parameters from high-risk infants with RH were compared with parameters from infants without RH...
September 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28516002/transplantation-of-human-embryonic-stem-cell-derived-retinal-cells-into-the-subretinal-space-of-a-non-human-primate
#20
Jennifer R Chao, Deepak A Lamba, Todd R Klesert, Anna La Torre, Akina Hoshino, Russell J Taylor, Anu Jayabalu, Abbi L Engel, Thomas H Khuu, Ruikang K Wang, Maureen Neitz, Jay Neitz, Thomas A Reh
PURPOSE: Previous studies have demonstrated the ability of retinal cells derived from human embryonic stem cells (hESCs) to survive, integrate into the host retina, and mediate light responses in murine mouse models. Our aim is to determine whether these cells can also survive and integrate into the retina of a nonhuman primate, Saimiri sciureus, following transplantation into the subretinal space. METHODS: hESCs were differentiated toward retinal neuronal fates using our previously published technique and cultured for 60 to 70 days...
May 2017: Translational Vision Science & Technology
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